Acta Paediatrica最新文献_第8页

Has the Rise of Celiac Disease Incidence in Estonian Children Stopped? 爱沙尼亚儿童乳糜泻发病率的上升已经停止了吗？

IF 2.4 4区医学

Acta Paediatrica Pub Date : 2025-04-11 DOI: 10.1111/apa.70092

Kärt Simre, Heti Pisarev, Mari-Liis Kumm, Marie Kaivo, Oivi Uibo

{"title":"Has the Rise of Celiac Disease Incidence in Estonian Children Stopped?","authors":"Kärt Simre, Heti Pisarev, Mari-Liis Kumm, Marie Kaivo, Oivi Uibo","doi":"10.1111/apa.70092","DOIUrl":"https://doi.org/10.1111/apa.70092","url":null,"abstract":"Aim: The aim of this study was to analyse the incidence and clinical presentation of childhood CD from 2011 to 2020 in Estonia and to compare the incidence with earlier published results of a 35-year period (1976-2010).Methods: Data was collected retrospectively about children up to 19 years of age who were newly diagnosed with CD from 2011 to 2020 in all of Estonia. CD was diagnosed mostly by biopsy and in only two cases by serology.Results: From 2011 to 2020, 189 new CD cases were diagnosed (113 girls, 60%, M/F ratio 1:1.49). The median age at diagnosis was 8.6 years. For comparison, from 1976 to 2010, the median age was 2.3 years. There were no differences between boys and girls (p = 0.93). Most frequently, the patients had atypical gastrointestinal symptoms. The incidence rate per 100 000 person-years in 2011-2020 was 6.89 (95% CI: 5.94-7.94). For comparison, in 1976-1980, the incidence rate per 100 000 person-years was 0.1.Conclusion: The median age at diagnosis increased markedly during the study period. From 1976 onward, there has been almost a 70-fold increase in the incidence rate of CD.","PeriodicalId":55562,"journal":{"name":"Acta Paediatrica","volume":" ","pages":""},"PeriodicalIF":2.4,"publicationDate":"2025-04-11","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144054815","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Urination Stimulation Techniques for Collecting Clean Urine Samples in Infants Under One Year: Systematic Review and Meta-Analysis. 1岁以下婴儿收集干净尿液样本的排尿刺激技术：系统回顾和荟萃分析。

IF 2.4 4区医学

Acta Paediatrica Pub Date : 2025-04-11 DOI: 10.1111/apa.70091

Francisco Javier Gómez-Manzano, Esperanza Barroso-Corroto, José Alberto Laredo-Aguilera, Rosa María Molina-Madueño, Sergio Rodríguez-Cañamero, Juan Manuel Carmona-Torres

{"title":"Urination Stimulation Techniques for Collecting Clean Urine Samples in Infants Under One Year: Systematic Review and Meta-Analysis.","authors":"Francisco Javier Gómez-Manzano, Esperanza Barroso-Corroto, José Alberto Laredo-Aguilera, Rosa María Molina-Madueño, Sergio Rodríguez-Cañamero, Juan Manuel Carmona-Torres","doi":"10.1111/apa.70091","DOIUrl":"https://doi.org/10.1111/apa.70091","url":null,"abstract":"Aim: To evaluate the efficacy of spontaneous urination stimulation techniques in infants under 1 year to obtain a clean and valid urine sample for analysis.Methods: Systematic review of randomised clinical trials. The databases consulted were PUBMED, SCOPUS, WEB OF SCIENCE, CINALH and the Virtual Health Library. The risk of bias was assessed via the RoB2 scale. A meta-analysis was performed to analyse the success rate of urine collection for both techniques and the contamination rate of the urine samples.Results: Seven studies were included in this review. The participants included 1122 infants, of whom a stimulation technique was performed in 667 (the technique of Herreros et al. was performed in 419 infants, and the \"Quick-Wee\" technique was performed in 248 infants). Success was measured by obtaining a midstream urine sample in less than 5 min. Urination stimulation is effective in obtaining a urine sample, especially at < 6 months of age.Conclusion: Stimulation of urination in infants is a noninvasive, fast, safe, economic and effective procedure that allows the capture of a valid urine sample in the middle of the stream for analysis.","PeriodicalId":55562,"journal":{"name":"Acta Paediatrica","volume":" ","pages":""},"PeriodicalIF":2.4,"publicationDate":"2025-04-11","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143996476","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Preterm Infants Who Did Not Need Positive Pressure Ventilation Had a Lower Heart Rate Immediately After Birth Than Healthy Term Infants. 不需要正压通气的早产儿在出生后立即心率低于健康足月婴儿。

IF 2.4 4区医学

Acta Paediatrica Pub Date : 2025-04-09 DOI: 10.1111/apa.70079

Line Norman Kvenshagen, Anne Lee Solevåg, Siren Rettedal, Amalie Kibsgaard, Joar Eilevstjønn, Kari Holte, Ketil Størdal

{"title":"Preterm Infants Who Did Not Need Positive Pressure Ventilation Had a Lower Heart Rate Immediately After Birth Than Healthy Term Infants.","authors":"Line Norman Kvenshagen, Anne Lee Solevåg, Siren Rettedal, Amalie Kibsgaard, Joar Eilevstjønn, Kari Holte, Ketil Størdal","doi":"10.1111/apa.70079","DOIUrl":"https://doi.org/10.1111/apa.70079","url":null,"abstract":"Aim: Our aim was to use electrocardiograms immediately after birth to determine the heart rates of healthy newborn infants by gestational age and mode of delivery.Methods: This prospective observational study was performed in two Norwegian hospitals from March 2019 to June 2021. We included infants with gestational ages of ≥ 28 weeks and no need for positive pressure ventilation. Continuous heart rate data were collected using dry electrode technology and were used to create percentile charts and compare heart rates by groups.Results: We enrolled 214 preterm and 2191 term newborn infants. The median (quartiles) heart rate at 60 s of age was 166 (150-181) beats per minute for preterm infants and 174 (158-187) for term infants (p < 0.05). Term infants born using vacuum extraction, forceps or emergency Caesarean sections had significantly higher heart rates than term infants born by unassisted vaginal deliveries or planned Caesarean sections. The median heart rates of the groups were all within the normal range.Conclusion: This study provided normative heart rate data for healthy newborn infants, by gestational age and delivery mode. Although the differences between the groups were statistically significant, they were of limited clinical significance and would not support changes in neonatal resuscitation measures.","PeriodicalId":55562,"journal":{"name":"Acta Paediatrica","volume":" ","pages":""},"PeriodicalIF":2.4,"publicationDate":"2025-04-09","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144042779","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Has the Misuse of Antibiotics Compromised a Vital 20th-Century Medical Advancement. 抗生素的滥用是否损害了20世纪重要的医学进步？

IF 2.4 4区医学

Acta Paediatrica Pub Date : 2025-04-08 DOI: 10.1111/apa.70061

Ian K Hewitt

引用次数: 0

A New Way of Knowing When a Newborn's Jaundice Is Dangerous: Are We Ready for 'R'? 一种了解新生儿黄疸危险的新方法：我们准备好“R”了吗？

IF 2.4 4区医学

Acta Paediatrica Pub Date : 2025-04-08 DOI: 10.1111/apa.70088

David K Stevenson, Ronald J Wong

引用次数: 0

Brain Activity Study Showed the Benefits of Parents Reading Printed Books to Their Children Rather Than Using Tablets. 大脑活动研究表明，父母为孩子阅读印刷书籍比使用平板电脑更有益。

IF 2.4 4区医学

Acta Paediatrica Pub Date : 2025-04-08 DOI: 10.1111/apa.70083

Mikael Heimann

引用次数: 0

Clinical Outcomes and Follow-Up in Children With Prenatally Detected Unilateral Ureteropelvic Junction Obstruction. 产前发现单侧肾盂输尿管连接处梗阻患儿的临床结局及随访。

IF 2.4 4区医学

Acta Paediatrica Pub Date : 2025-04-07 DOI: 10.1111/apa.70086

Tim Malmström, Zivile Bekassy, Martin Salö, Anna Röckert Tjernberg, Pernilla Stenström

{"title":"Clinical Outcomes and Follow-Up in Children With Prenatally Detected Unilateral Ureteropelvic Junction Obstruction.","authors":"Tim Malmström, Zivile Bekassy, Martin Salö, Anna Röckert Tjernberg, Pernilla Stenström","doi":"10.1111/apa.70086","DOIUrl":"https://doi.org/10.1111/apa.70086","url":null,"abstract":"Aim: To explore the possibility of reducing the diagnostic burden in children with prenatally detected unilateral ureteropelvic junction obstruction.Methods: Children with unilateral ureteropelvic junction obstruction (2012-2020) were identified from a prenatal hydronephrosis registry. The frequency of adverse events, predictors for event-free follow-up beyond 1 year of age, and examination burden in children with conservatively managed unilateral ureteropelvic junction obstruction were assessed. Adverse events included febrile urinary tract infections, > 10% decline in differential renal function, or both, leading to surgery. Follow-up ended at clinical conclusion or surgical decision.Results: Forty-seven children were included, with a follow-up of median 22.5 (2-115, min-max) months. Overall, 43% (20/47) had no adverse events. Adverse events occurred within 2 years in 85% (23/27). Predictors of event-free follow-up beyond 1 year were a postnatal anteroposterior diameter < 15 mm at 12 months (p < 0.001) or a stable anteroposterior diameter during the first year (p = 0.04). Patients without adverse events underwent a median of eight (3-26, min-max) diagnostic imaging examinations.Conclusions: In children with antenatally detected ureteropelvic junction obstruction, 43% had no adverse events, but a substantial examination burden. Predictors of a non-eventful trace, useful in guidelines, were a postnatal anteroposterior diameter < 15 mm or stable at 12 months.","PeriodicalId":55562,"journal":{"name":"Acta Paediatrica","volume":" ","pages":""},"PeriodicalIF":2.4,"publicationDate":"2025-04-07","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143796881","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Issue Highlights 问题突出

IF 2.4 4区医学

Acta Paediatrica Pub Date : 2025-04-07 DOI: 10.1111/apa.70068

Anna Käll, Hugo Lagercrantz

引用次数: 0

Oral Doxycycline Was a Safe and Feasible Treatment in Young Children With Neuroborreliosis. 口服强力霉素对患有神经源性疾病的幼儿是一种安全可行的治疗方法

IF 2.4 4区医学

Acta Paediatrica Pub Date : 2025-04-05 DOI: 10.1111/apa.70085

Joakim Bloch, Lisbeth Schmidt, Nadja Vissing, Jonathan Peter Glenthøj, Birgitte Smith, Alfred Peter Born, Anja Poulsen, Anne-Mette Lebech, Ulrikka Nygaard

{"title":"Oral Doxycycline Was a Safe and Feasible Treatment in Young Children With Neuroborreliosis.","authors":"Joakim Bloch, Lisbeth Schmidt, Nadja Vissing, Jonathan Peter Glenthøj, Birgitte Smith, Alfred Peter Born, Anja Poulsen, Anne-Mette Lebech, Ulrikka Nygaard","doi":"10.1111/apa.70085","DOIUrl":"https://doi.org/10.1111/apa.70085","url":null,"abstract":"Aim: There is limited evidence on the use of oral doxycycline in young children. We evaluated the feasibility and effectiveness of doxycycline in children under 9 years with neuroborreliosis.Methods: This retrospective study included all children under 9 years of age treated for neuroborreliosis in the Capital Region of Denmark from 2019 to 2023. Patients were identified through Borrelia burgdorferi antibody tests and International Classification of Disease, 10th revision codes. Outcomes were change of treatment route, intolerable adverse effects of oral doxycycline, progression of symptoms after treatment cessation, continuous symptoms of neuroborreliosis exceeding 6 months, and relapse of neuroborreliosis.Results: Of 116 children, 63 (54%) received doxycycline initially, 4 (6%) of whom switched to intravenous treatment due to adverse effects or symptom worsening during treatment. Of 46 (40%) receiving intravenous antibiotics followed by doxycycline, 45 (98%) completed the remaining treatment on doxycycline. Seven (6%) patients received intravenous antibiotics only. Of 109 patients receiving doxycycline, two (2%) experienced photosensitivity rash. Symptoms lasting over 6 months were observed in two patients. No patients had symptom progression or relapse during the follow-up period (median 41 months, range 12-66).Conclusion: Oral doxycycline was effective and feasible in children under 9 years with neuroborreliosis.","PeriodicalId":55562,"journal":{"name":"Acta Paediatrica","volume":" ","pages":""},"PeriodicalIF":2.4,"publicationDate":"2025-04-05","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143789441","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Medical Partnership Between Two Children's Hospitals in Ukraine and Sweden. 乌克兰和瑞典两家儿童医院之间的医疗伙伴关系。

IF 2.4 4区医学

Acta Paediatrica Pub Date : 2025-04-05 DOI: 10.1111/apa.70087

Zhovnir Volodymyr, Svante Norgren

引用次数: 0