Acta Paediatrica最新文献_第7页

The LMS method should not be used to construct velocity centiles in puberty. LMS 方法不应用于构建青春期的速度百分位数。

IF 2.4 4区医学

Acta Paediatrica Pub Date : 2024-11-21 DOI: 10.1111/apa.17511

T J Cole

引用次数: 0

Infectious morbidity and white blood cell count associated with grade repetition and school absenteeism. 与留级和旷课有关的传染病发病率和白细胞计数。

IF 2.4 4区医学

Acta Paediatrica Pub Date : 2024-11-21 DOI: 10.1111/apa.17513

Eduardo Villamor, Rachael J Beer, Allison L Seeley, Sandra López-Arana, Constanza Marín, Mercedes Mora-Plazas

{"title":"Infectious morbidity and white blood cell count associated with grade repetition and school absenteeism.","authors":"Eduardo Villamor, Rachael J Beer, Allison L Seeley, Sandra López-Arana, Constanza Marín, Mercedes Mora-Plazas","doi":"10.1111/apa.17513","DOIUrl":"https://doi.org/10.1111/apa.17513","url":null,"abstract":"Aim: Infections can impair cognitive development, but their role on adverse childhood educational outcomes is unknown. We examined the associations of infectious morbidity and inflammatory biomarkers with grade repetition and school absenteeism.Methods: We followed 2762 Colombian children aged 5-12 years for a school year. We quantified inflammatory biomarkers at enrolment and prospectively recorded incidence of gastrointestinal and respiratory infections, doctor visits and absent days from school using pictorial diaries. We estimated adjusted relative risks (ARR) with 95% confidence intervals (CI) for grade repetition and absenteeism by infectious morbidity burden and inflammatory biomarker categories, and percentages of the associations mediated through absenteeism.Results: Morbidity was associated with increased risk of grade repetition. ARR (95% CI) of grade repetition comparing high versus no incidence of gastrointestinal, respiratory and ear infections were, respectively, 2.17 (1.00, 4.72), 2.31 (1.28, 4.16) and 2.57 (1.13, 5.86). Infections also predicted school absenteeism, which mediated 35%, 31% and 38% of the corresponding morbidity-grade repetition associations. Elevated white blood cells (WBC), especially granulocytes, were related to increased grade repetition and school absenteeism risks.Conclusion: Childhood infections and elevated WBC are associated with grade repetition and school absenteeism. Absenteeism does not fully explain the morbidity-grade repetition associations.","PeriodicalId":55562,"journal":{"name":"Acta Paediatrica","volume":" ","pages":""},"PeriodicalIF":2.4,"publicationDate":"2024-11-21","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142683734","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Serum bone turnover markers were associated with bone mass in late prepuberty and early puberty. 血清骨转换标志物与青春前期晚期和青春期早期的骨量有关。

IF 2.4 4区医学

Acta Paediatrica Pub Date : 2024-11-21 DOI: 10.1111/apa.17510

Jakob Rempe, Björn E Rosengren, Lars Jehpsson, Per Swärd, Magnus Dencker, Magnus K Karlsson

{"title":"Serum bone turnover markers were associated with bone mass in late prepuberty and early puberty.","authors":"Jakob Rempe, Björn E Rosengren, Lars Jehpsson, Per Swärd, Magnus Dencker, Magnus K Karlsson","doi":"10.1111/apa.17510","DOIUrl":"https://doi.org/10.1111/apa.17510","url":null,"abstract":"Aim: To analyse the association between bone turnover markers and bone mass in children and young adults.Methods: This descriptive study followed 132 children (68 boys/64 girls) from Malmö, Sweden, as controls in a school-based intervention study (2000-2017). Height, weight, Tanner stage and bone mass were measured annually from ages 8 to 15 years, with follow-ups at 19 and 23 years of age. Serum markers for bone formation (bone-specific alkaline phosphatase (bALP), N-terminal propeptide of collagen type 1 (PINP), osteocalcin) and resorption (C-terminal telopeptide crosslinks (CTX), tartrate-resistant acid phosphatase (TRAcP 5b)) were collected at ages 9.9 ± 0.6 (mean ± SD) (n = 78), 12.0 ± 0.6 (n = 64), 14.9 ± 0.8 (n = 52), 18.8 ± 0.3 (n = 34) and 23.3 ± 0.6 years (n = 56).Results: Compared to girls, boys showed higher bone turnover markers at ages 15, 19 and 23 years (all p < 0.05). At 10 years of age (Tanner stage 1 and 2), bALP and TRAcP 5b correlated with current bone mass (adjusted for age and sex), while bALP, PINP, osteocalcin and CTX correlated with bone mass change over the next 2 years (adjusted for age, sex and interval) (all p < 0.05).Conclusion: Bone turnover markers in early Tanner stages predicted both current bone mass and subsequent bone mass changes.","PeriodicalId":55562,"journal":{"name":"Acta Paediatrica","volume":" ","pages":""},"PeriodicalIF":2.4,"publicationDate":"2024-11-21","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142689619","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

The Family Snapshot-Innovation to integrate family context into daily interactions in the NICU. 家庭快照--将家庭背景融入新生儿重症监护室日常互动的创新。

IF 2.4 4区医学

Acta Paediatrica Pub Date : 2024-11-21 DOI: 10.1111/apa.17503

Maya Dahan, Leahora Rotteau, Asaph Rolnitsky, Shelley Higazi, Ophelia Kwakye, Giselle W S Lai, Wendy Moulsdale, Lisa Sampson, Jennifer Stannard, Karel O'Brien, Paige Terrien Church

{"title":"The Family Snapshot-Innovation to integrate family context into daily interactions in the NICU.","authors":"Maya Dahan, Leahora Rotteau, Asaph Rolnitsky, Shelley Higazi, Ophelia Kwakye, Giselle W S Lai, Wendy Moulsdale, Lisa Sampson, Jennifer Stannard, Karel O'Brien, Paige Terrien Church","doi":"10.1111/apa.17503","DOIUrl":"https://doi.org/10.1111/apa.17503","url":null,"abstract":"Aim: Current literature favours individualised decision making, an approach that requires understanding patients within their context and tailoring treatment and recommendations to their unique needs. In neonatology, family context becomes synonymous with patient context. In the neonatal intensive care unit (NICU), the team may be challenged to understand the intricacies of the family context, paramount for both families and clinicians. However, a significant gap exists between the intent to share information about the family context and the process of doing so. The transformational goal of this project was to embed an understanding of the family context into all interactions that occur in the NICU between clinicians and families, and between clinicians when discussing patients.Methods: We designed and implemented the Family Snapshot (FS), an innovation to bridge the gap between the intent and the process to share the family context.Results: Two groups of process measures have been collected to understand workflow integration: (1) whether the forms are being used and (2) how the forms are being used. Overall, completion of at least some part of the FS was >90%.Conclusion: This manuscript describes our process, its feasibility and impact and presents two tools, the FS antenatal consultations and the FS tab.","PeriodicalId":55562,"journal":{"name":"Acta Paediatrica","volume":" ","pages":""},"PeriodicalIF":2.4,"publicationDate":"2024-11-21","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142683736","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Impact of antibiotic duration and type on short- and long-term outcomes in very-low-birthweight infants. 抗生素使用时间和类型对极低出生体重儿短期和长期预后的影响。

IF 2.4 4区医学

Acta Paediatrica Pub Date : 2024-11-19 DOI: 10.1111/apa.17509

Marcus Wing Choy Loe, Rehena Sultana, Guan Lin Goh, Selina Wan Xuan Lim, Kee Thai Yeo

{"title":"Impact of antibiotic duration and type on short- and long-term outcomes in very-low-birthweight infants.","authors":"Marcus Wing Choy Loe, Rehena Sultana, Guan Lin Goh, Selina Wan Xuan Lim, Kee Thai Yeo","doi":"10.1111/apa.17509","DOIUrl":"10.1111/apa.17509","url":null,"abstract":"Aim: To determine the association between the duration and types of antibiotic exposure and the occurrence of short- and long-term outcomes among preterm, very-low-birthweight (VLBW) infants.Methods: Retrospective cohort study of VLBW infants born <32 weeks gestation between January 2017-December 2021. Association between antibiotic exposure and the occurrence of death and/or major morbidities, and neurodevelopmental impairment (NDI) at 18-24 months corrected age, was evaluated.Results: A total of 728 infants were included-median gestation 28 weeks (IQR 26, 30) and median birthweight 1070g (IQR 850, 1300). Compared to no antibiotics, antibiotics exposure >3 days was significantly associated with increased risk of mortality and/or bronchopulmonary dysplasia (BPD)-adjusted odds ratio (AOR) 2.0 (95% CI 1.1-3.8; p=0.03), 3.5 (95% CI 1.6-7.8; p=0.01) and 3.8 (95% CI 1.6-9.0; p<0.001) corresponding to antibiotic exposure of 4-7 days, 8-14 and >14 days, respectively. Additional exposure to broad-spectrum antibiotics was associated with AOR of 3.2 (95% CI 1.6-6.5; p<0.01) for death and/or BPD. There was no significant association between antibiotic exposure and NDI.Conclusion: Infants who received >3 days of antibiotics and/or additional broad-spectrum antibiotics had significantly increased odds of death and/or BPD compared to no exposure. Antibiotic exposure was not significantly associated with NDI in our population.","PeriodicalId":55562,"journal":{"name":"Acta Paediatrica","volume":" ","pages":""},"PeriodicalIF":2.4,"publicationDate":"2024-11-19","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142669975","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

The four horsemen of clinical language. 临床语言的四骑士

IF 2.4 4区医学

Acta Paediatrica Pub Date : 2024-11-19 DOI: 10.1111/apa.17507

Jennifer Cobelli Kett, Luke Mosley, Aaron Wightman

引用次数: 0

Clinical outcomes in febrile children with a positive urine culture without pyuria: Implications for antibiotics. 尿培养阳性但无脓毒症的发热儿童的临床结果：对抗生素的影响。

IF 2.4 4区医学

Acta Paediatrica Pub Date : 2024-11-19 DOI: 10.1111/apa.17508

Rei Miyake, Hiroshi Hataya

{"title":"Clinical outcomes in febrile children with a positive urine culture without pyuria: Implications for antibiotics.","authors":"Rei Miyake, Hiroshi Hataya","doi":"10.1111/apa.17508","DOIUrl":"10.1111/apa.17508","url":null,"abstract":"Aim: This study aimed to investigate whether antibiotics should be administered to patients aged <2 years with a positive urine culture without pyuria by identifying their clinical characteristics and outcomes in the absence of antibiotic treatment.Methods: This retrospective, observational study included children aged <2 years with positive findings on a culture of urine obtained using a catheter in the paediatric emergency department between 2016 and 2021. The primary outcome was the spontaneous resolution of fever without antibiotics in patients with a positive urine culture without pyuria. The clinical characteristics of the patients with and without pyuria were also compared.Results: Of 391 patients, 86 (22%) were negative for pyuria. Of these, 63 (73%) received no antibiotics, and 56 (89%) had spontaneous defervescence and no symptom recurrence. The patients without pyuria had a higher proportion of other possible causes of fever, lower inflammatory markers, fewer cultured bacteria, and a higher proportion of multiple, bacterial species in their culture than the patients with pyuria.Conclusions: Most of the patients with a positive urine culture without pyuria may not require antibiotics if their fever resolves spontaneously.","PeriodicalId":55562,"journal":{"name":"Acta Paediatrica","volume":" ","pages":""},"PeriodicalIF":2.4,"publicationDate":"2024-11-19","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142669968","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Breastfeeding supports growth in small for gestational age infants: A systematic review and meta-analysis. 母乳喂养有助于小胎龄婴儿的生长：系统回顾和荟萃分析。

IF 2.4 4区医学

Acta Paediatrica Pub Date : 2024-11-19 DOI: 10.1111/apa.17490

Heather Resvick, Amber Foster, Brenda Hartman, Orlando DaSilva, Kevin Coughlin, Janet Madill

{"title":"Breastfeeding supports growth in small for gestational age infants: A systematic review and meta-analysis.","authors":"Heather Resvick, Amber Foster, Brenda Hartman, Orlando DaSilva, Kevin Coughlin, Janet Madill","doi":"10.1111/apa.17490","DOIUrl":"10.1111/apa.17490","url":null,"abstract":"Aim: Small for gestational age is defined as birthweight <10th percentile on standardised age and sex-specific growth charts. Rapid catch-up growth seen post-natal is associated with adiposity and cardiometabolic syndromes later in life. Breastfeeding has positive effects on growth in premature and low-birthweight infants. Therefore, examining the impact of exclusive breastfeeding on growth parameters in small for gestational age infants is important.Methods: The Preferred Reporting Items for Systematic Reviews and Meta-Analyses statement and checklist guided review and meta-analysis. Four databases were searched.Results: Five articles (4702 infants) met inclusion criteria. The effect of 4-6 months of breastfeeding on growth was measured using weight, length, head circumference, z-scores and change between timepoints. Study quality was considered very low using Grading of Recommendations, Assessment, Development and Evaluation tool. Random effects models assessed the effect of breastfeeding on weight and length catch-up growth. Differences in weight and length were seen (-8.36, 95%CI: -11.26 to -5.46 and -7.50, 95%CI: -1.92 to -4.18, p < 0.001), with substantial heterogeneity (I2 > 90%).Conclusions: Breastmilk supports growth in small for gestational age infants, though limited evidence exists for catch-up growth in the first 6 months. The magnitude and direction of the effect could not be determined.","PeriodicalId":55562,"journal":{"name":"Acta Paediatrica","volume":" ","pages":""},"PeriodicalIF":2.4,"publicationDate":"2024-11-19","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142669962","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Charting the history of premature birth in France from the 17th century to modern state-of-the art care. 介绍法国从 17 世纪到现代先进护理技术的早产史。

IF 2.4 4区医学

Acta Paediatrica Pub Date : 2024-11-19 DOI: 10.1111/apa.17506

Agathe Houzé de l'Aulnoit, Marie-Laure Charkaluk, Emmanuel Drouin

{"title":"Charting the history of premature birth in France from the 17th century to modern state-of-the art care.","authors":"Agathe Houzé de l'Aulnoit, Marie-Laure Charkaluk, Emmanuel Drouin","doi":"10.1111/apa.17506","DOIUrl":"10.1111/apa.17506","url":null,"abstract":"Aim: To describe the concept of preterm birth in the history of medicine in France, from the 17th century up until the end of the 20th century, on the basis of old medical textbooks.Methods: Historical manuscripts and books held in medical libraries and from our personal collection were examined. Digital copies of medical textbooks online were also studied.Results: Premature deliveries were often referred to as spontaneous abortions or miscarriages, irrespective of the infant's condition at birth. The difference between growth restriction and prematurity was not known. At the end of the 18th century, care for newborn infants entered the age of modern medicine, with observations of the newborn infant and its illnesses and experiments concerning nutrition and thermoregulation treatments. The responsibility for newborn infants, long allocated to midwives and obstetricians, was passed to neonatologists and paediatricians in the 1960s, thanks to developments in our knowledge of neonatal physiology in general and respiration, nutrition and thermoregulation in particular.Conclusion: This article delays the history of medicine concerned the care of preterm infants by obstetricians and then neonatologists, from the 17th century to modern period.","PeriodicalId":55562,"journal":{"name":"Acta Paediatrica","volume":" ","pages":""},"PeriodicalIF":2.4,"publicationDate":"2024-11-19","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142669964","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Impact of a music intervention on heart rate variability in very preterm infants. 音乐干预对早产儿心率变异性的影响。

IF 2.4 4区医学

Acta Paediatrica Pub Date : 2024-11-19 DOI: 10.1111/apa.17500

Francisca Barcos-Munoz, Alfredo I Hernández, Marlene A Abreu De Araujo, Sébastien Fau, Manuela Filippa, Petra S Hüppi, Alain Beuchée, Olivier Baud

{"title":"Impact of a music intervention on heart rate variability in very preterm infants.","authors":"Francisca Barcos-Munoz, Alfredo I Hernández, Marlene A Abreu De Araujo, Sébastien Fau, Manuela Filippa, Petra S Hüppi, Alain Beuchée, Olivier Baud","doi":"10.1111/apa.17500","DOIUrl":"10.1111/apa.17500","url":null,"abstract":"Aim: Infants born very preterm spend their early postnatal life in a neonatal intensive care unit, where irregular and unpredictable sounds replace the structured and familiar intrauterine auditory environment. Music interventions may contribute to alleviate these deleterious effects by reducing stress and providing a form of environmental enrichment.Material and methods: This was an ancillary study as part of a blinded randomised controlled clinical trial entitled the effect of music on preterm infant's brain development. It measured the impact of music listening on the autonomic nervous system (ANS), we assessed heart rate variability (HRV) through high-resolution recordings of heart rate monitoring, at three specific postmenstrual ages in premature infants.Results: From 29 included subjects, 18 were assessed for complete HRV dataset, including nine assigned to the music intervention and nine to the control group. Postmenstrual age appeared to be the main factor influencing HRV from 33 weeks to term equivalent age. Further analyses did not reveal any detectable effect of music intervention on ANS response.Conclusion: This study found that ANS responses were not modified by recorded music intervention in very preterm infants during wakefulness or sleep onset. Further research is warranted to explore other factors influencing ANS development in this population.","PeriodicalId":55562,"journal":{"name":"Acta Paediatrica","volume":" ","pages":""},"PeriodicalIF":2.4,"publicationDate":"2024-11-19","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142669972","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0