Acta Paediatrica最新文献_第2页

Parental Consent to a Neonatal Clinical Study: The Roles of Uncertainty, Burden of Sample Collection and Societal Expectations. 父母同意新生儿临床研究：不确定性，样本收集负担和社会期望的作用。

IF 2.1 4区医学

Acta Paediatrica Pub Date : 2025-10-06 DOI: 10.1111/apa.70333

Susanne Soendergaard Kappel, Gustav Riemer Jakobsen, Kija Lin Oestergaard, Anders Brunse, Dennis Sandris Nielsen, Lise Aunsholt

{"title":"Parental Consent to a Neonatal Clinical Study: The Roles of Uncertainty, Burden of Sample Collection and Societal Expectations.","authors":"Susanne Soendergaard Kappel, Gustav Riemer Jakobsen, Kija Lin Oestergaard, Anders Brunse, Dennis Sandris Nielsen, Lise Aunsholt","doi":"10.1111/apa.70333","DOIUrl":"https://doi.org/10.1111/apa.70333","url":null,"abstract":"Aim: Recruiting participants for neonatal clinical studies may be challenging because parental consent is required shortly after birth. This study aimed to explore reasons for parental decline of participation in a neonatal study.Method: This qualitative sub-study was conducted in the Capital Region of Denmark between June 2022 and April 2023. Parents of healthy term newborn infants who declined participation in the PrePhage study, a study investigating the transfer of faecal filtrate for the prevention of necrotising enterocolitis, were included. These parents were interviewed through semi-structured telephone interviews. Data were analysed using thematic analysis.Results: Ten parents (five mothers and five fathers of 10 different newborn infants) participated. All were first-time parents. Three themes were identified: the first theme, uncertainty of the unknown, captured how early parenthood influenced willingness to engage. The second theme, challenges and discomfort related to sample collection, reflected logistical burdens and discomfort associated with faecal samples. The third theme, balancing societal expectations, described the tension between the social value of research and expressed guilt for declining participation.Conclusion: Emotional, logistical and societal factors influenced parents' decision to decline participation in neonatal research. Future enrolment strategies should consider the timing of approach and aim to minimise participation burden.Trial registration: ClinicalTrials.gov identifier: NCT05272579 and NCT05272566.","PeriodicalId":55562,"journal":{"name":"Acta Paediatrica","volume":" ","pages":""},"PeriodicalIF":2.1,"publicationDate":"2025-10-06","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145233581","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Persistent Neonatal Risks in Maternal Type 1 Diabetes: A Call for Improved Maternal Care. 孕产妇1型糖尿病的持续新生儿风险：呼吁改善孕产妇保健。

IF 2.1 4区医学

Acta Paediatrica Pub Date : 2025-10-03 DOI: 10.1111/apa.70323

Sophia Brismar Wendel

引用次数: 0

Growth Charts: From Pen and Paper to Computerised Algorithms to Detect Aberrant Growth. 增长图表：从纸笔到计算机化算法检测异常增长。

IF 2.1 4区医学

Acta Paediatrica Pub Date : 2025-10-03 DOI: 10.1111/apa.70328

Petur B Juliusson, Mathieu Roelants

引用次数: 0

A National Sample of Swedish Young Children Shows Sociodemographic Variations in Physical Activity and Screen Time. 瑞典幼儿的全国样本显示了社会人口在体育活动和屏幕时间方面的差异。

IF 2.1 4区医学

Acta Paediatrica Pub Date : 2025-10-02 DOI: 10.1111/apa.70321

Gisela Nyberg, Björg Helgadóttir, Lotta Moraeus, Jessica Petrelius Sipinen, Anna-Karin Lindroos, Andreas Fröberg

{"title":"A National Sample of Swedish Young Children Shows Sociodemographic Variations in Physical Activity and Screen Time.","authors":"Gisela Nyberg, Björg Helgadóttir, Lotta Moraeus, Jessica Petrelius Sipinen, Anna-Karin Lindroos, Andreas Fröberg","doi":"10.1111/apa.70321","DOIUrl":"https://doi.org/10.1111/apa.70321","url":null,"abstract":"Aim: To investigate physical activity (PA), sedentary time, and screen time by age, sex, and parental education in a national sample of young children.Method: This cross-sectional study, conducted 2021-2024, of Swedish children recruited via their parents, included 1078 children aged 18 months, mean 1.5 ± 0.1 years, and 750 aged four, mean 4.1 ± 0.1 years. PA, sedentary time, and screen time were measured with accelerometry and questionnaire.Results: PA guidelines were met by 94% of the 18-month-old children and 51% of those 4 years old. Among 18-month-old children, 22% met screen time guidelines on weekdays and 17% on weekends; corresponding percentages among children 4 years old were 60% and 28%. Device-measured PA levels were consistently lower for girls than boys at age four, but sex differences were small among 18-month-old children. More children whose parents were highly educated participated in organised activities and used active transport modes; they also had lower screen time than children whose parents had low education.Conclusion: Nearly all 18-month-old children met PA guidelines, versus only half of those aged 4 years. Many children in both age groups exceeded screen time guidelines. Age, sex, and parental education were associated with children's PA and screen time, suggesting targeted interventions.","PeriodicalId":55562,"journal":{"name":"Acta Paediatrica","volume":" ","pages":""},"PeriodicalIF":2.1,"publicationDate":"2025-10-02","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145214153","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Chronic Lung Disease-Related Pulmonary Hypertension in Children. 儿童慢性肺病相关肺动脉高压

IF 2.1 4区医学

Acta Paediatrica Pub Date : 2025-09-30 DOI: 10.1111/apa.70320

Jason E Lang, Kevin D Hill

{"title":"Chronic Lung Disease-Related Pulmonary Hypertension in Children.","authors":"Jason E Lang, Kevin D Hill","doi":"10.1111/apa.70320","DOIUrl":"https://doi.org/10.1111/apa.70320","url":null,"abstract":"Aim: Pulmonary hypertension (PH) is characterised by elevated pressures in the pulmonary arterial system. Despite its high mortality, paediatric PH has few approved treatments. Our aim was to review the latest diagnostic and treatment considerations for paediatric PH, with particular emphasis on WHO group 3 chronic lung disease/hypoxia-related pulmonary hypertension (CLD-PH).Methods: Two subspecialists caring for children with CLD-PH conducted a narrative review of the latest expert guidelines and published pharmacotherapeutic data relevant to CLD-PH.Results: Bronchopulmonary dysplasia (BPD) is the leading cause of CLD-PH; up to 30% of infants with BPD develop PH. Extreme prematurity, mechanical ventilation, infection and genetic predisposition contribute to vascular growth arrest, remodelling and increased pulmonary vascular resistance. Other conditions with lung hypoplasia and CLD-PH include congenital diaphragmatic hernia (CDH) and Down syndrome. Children with PH should be monitored by a specialised team experienced in cardiac monitoring, lung function/exercise testing, PH pharmacotherapy and the typical CLD-PH comorbidities. The most common therapy options include supplemental oxygen, phosphodiesterase inhibitors, endothelin receptor antagonists and prostacyclin agonists.Conclusion: CLD-PH in children is a complex condition that requires a thorough understanding of its aetiology, assessment methods, management strategies and supportive, family-centred care to improve outcomes for children with CLD-PH.","PeriodicalId":55562,"journal":{"name":"Acta Paediatrica","volume":" ","pages":""},"PeriodicalIF":2.1,"publicationDate":"2025-09-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145202083","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Utilising Cot-Side Cameras in Neonatal Intensive Care Unit for Deep Learning-Assisted General Movement Assessment. 在新生儿重症监护病房使用床边摄像头进行深度学习辅助的一般运动评估。

IF 2.1 4区医学

Acta Paediatrica Pub Date : 2025-09-30 DOI: 10.1111/apa.70319

Stephanie Baker, Meegan Kilcullen, Yogavijayan Kandasamy

{"title":"Utilising Cot-Side Cameras in Neonatal Intensive Care Unit for Deep Learning-Assisted General Movement Assessment.","authors":"Stephanie Baker, Meegan Kilcullen, Yogavijayan Kandasamy","doi":"10.1111/apa.70319","DOIUrl":"https://doi.org/10.1111/apa.70319","url":null,"abstract":"Aim: Neonatal units are increasingly utilising cot-side cameras to connect parents with their infants. Combined with deep learning, video obtained through cot-side cameras could assist clinicians in conducting seamless general movement assessment (GMA) of the writhing age.Method: A literature search was conducted using PubMed, Embase and SCOPUS with the following keywords: cot-side cameras, deep learning, artificial intelligence, general movement assessment and writhing age.Results: Methods for acquiring and classifying human movement are categorised into contact, non-contact and hybrid approaches. Contact modalities typically include wearable sensors placed on the body to represent human posture, while hybrid modalities combine wearable sensors or markers with non-contact sensors. Non-contact approaches include radar-based and vision-based methods, which are the most common and accessible for motion capture, employing standard or specialised cameras to capture video data. Cot-side cameras used in neonatal clinics are primarily standard red-green-blue (RGB) devices and are the leading candidates for automated GMA. Advances in deep learning can enhance motion assessment with video data through appearance- and pose-based methods, supporting computer-aided GMA.Conclusion: Advances in deep learning can enhance the motion assessment of RGB video data, offering a scalable and non-invasive solution for computer-aided GMA that could reshape early neurodevelopmental screening.","PeriodicalId":55562,"journal":{"name":"Acta Paediatrica","volume":" ","pages":""},"PeriodicalIF":2.1,"publicationDate":"2025-09-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145193893","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Adrenal Insufficiency in Children With Nephrotic Syndrome Treated With High Doses of Glucocorticoids. 高剂量糖皮质激素治疗肾病综合征患儿肾上腺功能不全。

IF 2.1 4区医学

Acta Paediatrica Pub Date : 2025-09-30 DOI: 10.1111/apa.70317

Claudia Mau Kai, Hanne Nørgaard, Line Thousig Sehested, Katharina M Main, Ida Maria Schmidt

引用次数: 0

Impact of the Transition Council in Type 1 Diabetes: Bridging the Gap to Adult Care. 1型糖尿病过渡委员会的影响：弥合成人护理的差距。

IF 2.1 4区医学

Acta Paediatrica Pub Date : 2025-09-30 DOI: 10.1111/apa.70324

Erhan Hocaoglu, Hatice Nursoy, Filiz Mercan Saridas, Muge Yasar, Kadircan Karatoprak, Yasemin Denkboy Ongen, Ozen Oz Gul, Canan Ersoy, Erdal Eren, Soner Cander

{"title":"Impact of the Transition Council in Type 1 Diabetes: Bridging the Gap to Adult Care.","authors":"Erhan Hocaoglu, Hatice Nursoy, Filiz Mercan Saridas, Muge Yasar, Kadircan Karatoprak, Yasemin Denkboy Ongen, Ozen Oz Gul, Canan Ersoy, Erdal Eren, Soner Cander","doi":"10.1111/apa.70324","DOIUrl":"https://doi.org/10.1111/apa.70324","url":null,"abstract":"Aim: This retrospective study evaluates the impact of the transition council on clinic attendance, glycaemic control and complications in type 1 diabetes.Methods: Since 2015, monthly multidisciplinary transition meetings (transition councils) have been held involving paediatric and adult endocrinology departments at Bursa Uludag University Hospital, Turkey. The study retrospectively compared outcomes of type 1 diabetes patients who transitioned to adult care via the council versus standard transition. A total of 180 patients (90 in each group) aged at transition 18-21 years (58.9% male) were included.Results: Within 6 months post-transition, 84.9% of council patients (exposed group) and 54.1% of the standard care group attended at least one visit (p < 0.001). Regular follow-up during the first year was significantly higher in the exposed group (58.1% vs. 29.7%, p < 0.001); rates were similar between groups in subsequent years. HbA1c levels increased significantly 1 year after transition in the standard care group (p = 0.025), while the exposed group remained stable (p = 0.719). No significant differences were observed in hospitalisation or diabetic ketoacidosis.Conclusion: This transition model may improve regular follow-up rates during the challenging first year of transition and help prevent additional deterioration in glycaemic control compared to standard care. Prospective randomised trials could strengthen these findings.","PeriodicalId":55562,"journal":{"name":"Acta Paediatrica","volume":" ","pages":""},"PeriodicalIF":2.1,"publicationDate":"2025-09-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145193934","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

EBNEO Commentary: Early Administration of Hydrocortisone Versus Placebo in Neonatal Shock-A Double Blind Randomised Controlled Trial. EBNEO评论：早期给予氢化可的松与安慰剂治疗新生儿休克——一项双盲随机对照试验。

IF 2.1 4区医学

Acta Paediatrica Pub Date : 2025-09-28 DOI: 10.1111/apa.70318

Prakash Kannan Loganathan, Su Wei Ng

引用次数: 0

Estimated Prevalence of Compliance With Muscle-Strengthening Activity Recommendations in Children and Adolescents: A Meta-Analysis. 儿童和青少年肌肉强化活动建议依从性的估计患病率：一项荟萃分析。

IF 2.1 4区医学

Acta Paediatrica Pub Date : 2025-09-27 DOI: 10.1111/apa.70315

Antonio García-Hermoso, Jacinto Muñoz-Pardeza, Ignacio Hormazábal-Aguayo, Yasmin Ezzatvar

{"title":"Estimated Prevalence of Compliance With Muscle-Strengthening Activity Recommendations in Children and Adolescents: A Meta-Analysis.","authors":"Antonio García-Hermoso, Jacinto Muñoz-Pardeza, Ignacio Hormazábal-Aguayo, Yasmin Ezzatvar","doi":"10.1111/apa.70315","DOIUrl":"https://doi.org/10.1111/apa.70315","url":null,"abstract":"Aim: To estimate the prevalence of meeting the World Health Organization (WHO) guidelines for muscle-strengthening activities in children and adolescents, specifically engaging in these activities at least 3 days per week, and explore, whenever possible, this prevalence according to sociodemographic and healthy habits factors.Methods: Four databases were systematically searched for studies published from inception to January 2025. Eligible studies included articles with samples of children and adolescents reporting the prevalence of meeting the muscle-strengthening activities guidelines.Results: Twenty-nine studies comprising 1 273 544 children and adolescents (49.40% girls; mean age: 13.40 years) from 36 countries were included. Estimated prevalence of muscle-strengthening activities was 38.51% (95% CI, 34.35% to 42.75%), based primarily on studies involving adolescent populations, with limited data available for children aged 6 to 12 years. According to the subgroup analyses, the predictors that favour compliance with the muscle-strengthening activity guidelines are being a boy, having normal weight, meeting the aerobic physical activity recommendations and receiving high family support for engaging in physical activity.Conclusion: Only 4 out of 10 children and adolescents meet the WHO muscle-strengthening activity guidelines. Targeted efforts are needed, particularly for girls and those with lower support or physical activity levels, to improve participation and youth fitness.Trial registration: PROSPERO Registration Number: CRD42025648274.","PeriodicalId":55562,"journal":{"name":"Acta Paediatrica","volume":" ","pages":""},"PeriodicalIF":2.1,"publicationDate":"2025-09-27","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145179975","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0