Acta Paediatrica最新文献_第2页

Vaginal Deliveries Were as Safe as Cesarean Sections for the Long-Term Cardiovascular Health of Preterm Twins. 对于早产双胞胎的长期心血管健康而言，阴道分娩与剖宫产一样安全。

IF 2.4 4区医学

Acta Paediatrica Pub Date : 2025-04-03 DOI: 10.1111/apa.70081

Dor Nissim, Eyal Sheiner, Tamar Wainstock, Shayna Miodownik, Gali Pariente

{"title":"Vaginal Deliveries Were as Safe as Cesarean Sections for the Long-Term Cardiovascular Health of Preterm Twins.","authors":"Dor Nissim, Eyal Sheiner, Tamar Wainstock, Shayna Miodownik, Gali Pariente","doi":"10.1111/apa.70081","DOIUrl":"https://doi.org/10.1111/apa.70081","url":null,"abstract":"Aim: There is no established consensus on the safest or most beneficial delivery mode for preterm twins. We assessed the associations between how premature twins were delivered and their long-term cardiovascular morbidity during childhood.Methods: A retrospective cohort study was conducted at the Soroka University Medical Center, the only tertiary hospital in southern Israel, which provides obstetric services to the whole country. Twins born between 1991 and 2021 were included, and their cardiovascular morbidity was followed up until 18 years of age. Data was collected from the hospital's databases. A Kaplan-Meier survival curve compared cumulative cardiovascular morbidity between the groups, and a Cox proportional hazard model adjusted the data for confounders.Results: The study comprised 6856 premature twins: 3986 (58.1%) were born via Caesarean delivery and the other 2870 (41.9%) were born by vaginal delivery. Long-term cardiovascular morbidity rates were comparable between twins born vaginally and via Cesarean delivery. Likewise, the cumulative incidence of long-term cardiovascular morbidity did not differ. The Cox proportional hazard model, which controlled for maternal age, diabetes mellitus and hypertensive disorders, showed no associations with the two delivery groups.Conclusion: No associations were documented between delivery mode in preterm twins and childhood cardiovascular morbidity.","PeriodicalId":55562,"journal":{"name":"Acta Paediatrica","volume":" ","pages":""},"PeriodicalIF":2.4,"publicationDate":"2025-04-03","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143775025","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Responding to Comments on Neonatal Transport for Outborn Extremely Preterm Infants. 对超出生极早产儿新生儿转运的评论回应。

IF 2.4 4区医学

Acta Paediatrica Pub Date : 2025-04-02 DOI: 10.1111/apa.70063

Christian Gadsbøll, Lars Björklund, David Ley

引用次数: 0

Parents Are Willing to Support Future Studies: A Cross-Sectional Study on Involvement in Neonatal Research. 父母愿意支持未来的研究：参与新生儿研究的横断面研究。

IF 2.4 4区医学

Acta Paediatrica Pub Date : 2025-03-30 DOI: 10.1111/apa.70078

Christine Arnold, Dina Hediger, Julian Eychmüller, Stephanie Vanessa Schmid, Sophie Jaisli, Carmen Haschke, Lisa Marie Bünte, André Kidszun

{"title":"Parents Are Willing to Support Future Studies: A Cross-Sectional Study on Involvement in Neonatal Research.","authors":"Christine Arnold, Dina Hediger, Julian Eychmüller, Stephanie Vanessa Schmid, Sophie Jaisli, Carmen Haschke, Lisa Marie Bünte, André Kidszun","doi":"10.1111/apa.70078","DOIUrl":"https://doi.org/10.1111/apa.70078","url":null,"abstract":"Aim: The aim of the study was to explore the views of parents of preterm infants regarding their involvement in neonatal research for quality improvement.Methods: This cross-sectional observational study included German-speaking parents of preterm infants who had previously participated in a web-based randomised controlled trial. The self-developed questionnaire included nine questions about parental involvement in neonatal research in four areas: research priorities, research tasks, availability of participants, and reimbursement of expenses. Data analysis was descriptive.Results: In total, 187 parents participated. Suggestions for research priorities were primarily related to three areas: infant neurodevelopment, support for parents during their time in the neonatal unit, and parental mental health. In terms of research tasks, the most frequently mentioned were feedback on study material (n = 91, 48.7%) and support for data collection (n = 43, 23.0%). In total, 59 (31.6%) parents indicated their willingness to attend two meetings per year. With regard to reimbursement of expenses, 117 (62.6%) parents indicated that covering travel and parking costs was a priority.Conclusion: Parents who have participated in clinical trials are a good source for patient and public involvement. They are willing to participate and have specific ideas about neonatal research with a focus on neurodevelopment.","PeriodicalId":55562,"journal":{"name":"Acta Paediatrica","volume":" ","pages":""},"PeriodicalIF":2.4,"publicationDate":"2025-03-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143756002","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Swedish Nationwide Study Found That Prematurity Was Associated With Kawasaki Disease. 瑞典全国性研究发现早产与川崎病有关。

IF 2.4 4区医学

Acta Paediatrica Pub Date : 2025-03-28 DOI: 10.1111/apa.70071

Anna Frisk, André Rudolph, Håkan Eliasson, Felicia Nordenstam, Gunnar Bergman, Marie Wahren-Herlenius, Johannes Mofors

{"title":"Swedish Nationwide Study Found That Prematurity Was Associated With Kawasaki Disease.","authors":"Anna Frisk, André Rudolph, Håkan Eliasson, Felicia Nordenstam, Gunnar Bergman, Marie Wahren-Herlenius, Johannes Mofors","doi":"10.1111/apa.70071","DOIUrl":"https://doi.org/10.1111/apa.70071","url":null,"abstract":"Aim: Our aim was to identify perinatal and parental risk factors for Kawasaki disease (KD).Methods: Swedish patient and population registers were used to identify children diagnosed with KD and unaffected matched controls from 1987 to 2018. Logistic regression models were used to estimate odds ratios (OR) and 95% confidence intervals (CI) following exposure to perinatal and parental factors.Results: We identified 1645 cases (61% male) and 15 463 matched controls. The median age of KD diagnoses was 2.6 years. Preterm birth was significantly associated with increased odds of developing KD (OR 1.24, 95% CI 1.01-1.53), particularly for children diagnosed before 1 year of age (OR 1.82, 95% CI 1.15-2.86). Prenatal maternal smoking was also associated with diagnoses before 1 year of age and the risk was increased in males if their mothers were 35 years of age or older at the time of delivery. The risk was higher among children of Asian or African descent. Perinatal factors had a higher impact on the risk of KD in children with Asian parents.Conclusion: Prematurity was significantly associated with an increased risk of developing KD. Other risks were prenatal maternal smoking, advanced maternal age, and being of Asian or African descent.","PeriodicalId":55562,"journal":{"name":"Acta Paediatrica","volume":" ","pages":""},"PeriodicalIF":2.4,"publicationDate":"2025-03-28","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143733131","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Early Career Progression in Young Adults With Coeliac Disease-A Register-Based Retrospective Cohort Study. 患有乳糜泻的年轻成年人的早期职业发展——基于登记的回顾性队列研究

IF 2.4 4区医学

Acta Paediatrica Pub Date : 2025-03-27 DOI: 10.1111/apa.70073

Katarina Johansson, Fredrik Norström, Anneli Ivarsson, Linda Richter Sundberg, Anders Själander, Amelie Therrien, Jocelyn Silvester, Anna Myleus

{"title":"Early Career Progression in Young Adults With Coeliac Disease-A Register-Based Retrospective Cohort Study.","authors":"Katarina Johansson, Fredrik Norström, Anneli Ivarsson, Linda Richter Sundberg, Anders Själander, Amelie Therrien, Jocelyn Silvester, Anna Myleus","doi":"10.1111/apa.70073","DOIUrl":"https://doi.org/10.1111/apa.70073","url":null,"abstract":"Aim: To investigate early career progression and national insurance use in young adults with paediatric coeliac disease.Methods: We performed a register study of a population born in Sweden between 1976 and 1992. Coeliac disease was diagnosed before 15 years of age. The comparison population was matched 4:1 by sex, region of residence at birth and birth year/month. We analysed education, employment, income, job position and national insurance use (sickness benefits, parental leave benefits and social welfare provision) at 25 and 30 years of age.Results: We identified 1812 individuals with coeliac disease (6888 comparison population) at 25 years of age and 263 individuals (984 comparison population) at 30 years of age. No statistically significant differences were seen in education, employment, income, job position, use of parental leave benefits or social welfare provision. More individuals with coeliac disease used sickness benefits at age 25 years (OR 1.34 [95% CI 1.12-1.59]).Conclusion: In this register study, we showed that coeliac disease diagnosed in childhood does not cause disadvantages on career progression on a population level. However, findings suggest that coeliac disease increases the risk for sickness benefit use.","PeriodicalId":55562,"journal":{"name":"Acta Paediatrica","volume":" ","pages":""},"PeriodicalIF":2.4,"publicationDate":"2025-03-27","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143733104","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Persisting Motor Function Problems in Children With Oesophageal Atresia Associated With Surgical Approach and Sports. 与手术入路和运动相关的食管闭锁儿童的持续运动功能问题。

IF 2.4 4区医学

Acta Paediatrica Pub Date : 2025-03-26 DOI: 10.1111/apa.70074

Anne-Fleur R L van Hal, Sophie de Munck, Tabitha P L Zanen-van den Adel, Joost van Rosmalen, Saskia J Gischler, Hanneke IJsselstijn, John Vlot, Leontien C C Toussaint-Duyster

{"title":"Persisting Motor Function Problems in Children With Oesophageal Atresia Associated With Surgical Approach and Sports.","authors":"Anne-Fleur R L van Hal, Sophie de Munck, Tabitha P L Zanen-van den Adel, Joost van Rosmalen, Saskia J Gischler, Hanneke IJsselstijn, John Vlot, Leontien C C Toussaint-Duyster","doi":"10.1111/apa.70074","DOIUrl":"https://doi.org/10.1111/apa.70074","url":null,"abstract":"Aim: Children born with oesophageal atresia are at risk for impaired motor function, yet longitudinal data are lacking. This study aimed to assess overall motor functioning, motor domains and potential predictors at school age over time.Methods: A prospective observational cohort study conducted within a tertiary university hospital's follow-up programme. Outcomes included overall motor performance and specific subdomains: manual dexterity, ball skills and balance.Results: Data from 161 children (84% oesophageal atresia type C) assessed at 5, 8 and 12 years showed estimated mean (95% CI) z-scores of -0.61 (-0.79 to -0.44), -0.35 (-0.53 to -0.16) and -0.56 (-0.77 to -0.34), respectively. At all ages and across subdomains, the proportion of children with definite motor impairments was significantly higher than the normative population (all p < 0.05). Univariable analyses identified lower gestational age, longer anaesthetic exposure, no sports participation and lower socio-economic status (all p < 0.05) as risk factors for impaired motor functioning. Multivariable analyses identified sports participation (p = 0.005) and, at 8 years, absence of thoracotomy (p < 0.001) as independent predictors.Conclusion: School-aged children born with oesophageal atresia remain at risk for persistent motor impairments. Encouraging sports participation is recommended, and further research is needed to explore the underlying mechanisms of motor impairment.","PeriodicalId":55562,"journal":{"name":"Acta Paediatrica","volume":" ","pages":""},"PeriodicalIF":2.4,"publicationDate":"2025-03-26","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143712253","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Nirsevimab Immunisation Significantly Reduces Respiratory Syncytial Virus-Associated Bronchiolitis Hospitalisations and Alters Seasonal Patterns. 尼西维单抗免疫显著减少呼吸道合胞病毒相关的毛细支气管炎住院治疗并改变季节性模式。

IF 2.4 4区医学

Acta Paediatrica Pub Date : 2025-03-26 DOI: 10.1111/apa.70066

Juan Manuel Rius-Peris, Enrique Palomo-Atance, Eva Muro-Díaz, Cristina Llorente-Ruiz, Laura Murcia-Clemente, Raúl Alcaraz

{"title":"Nirsevimab Immunisation Significantly Reduces Respiratory Syncytial Virus-Associated Bronchiolitis Hospitalisations and Alters Seasonal Patterns.","authors":"Juan Manuel Rius-Peris, Enrique Palomo-Atance, Eva Muro-Díaz, Cristina Llorente-Ruiz, Laura Murcia-Clemente, Raúl Alcaraz","doi":"10.1111/apa.70066","DOIUrl":"https://doi.org/10.1111/apa.70066","url":null,"abstract":"Aim: This work was performed to assess the impact of nirsevimab immunisation on acute bronchiolitis hospitalisations during nearly the entire 2023-2024 epidemic year.Methods: An observational, multicentre, prospective study was conducted from 1 September 2021 to 15 June 2024 across 20 hospitals in two Spanish regions. Infants up to 12 months old admitted for acute bronchiolitis were included. Demographic, clinical and microbiological data were analysed across three epidemic years (2021-2022, 2022-2023 and 2023-2024). Statistical analyses were performed to evaluate the effectiveness of nirsevimab in preventing respiratory syncytial virus (RSV)-associated hospitalisations.Results: In total, 2656 patients were included. Bronchiolitis hospitalisations significantly declined in the post-nirsevimab epidemic year compared with previous years. The 2023-2024 season displayed a bimodal distribution, with the first peak dominated by RSV cases and the second by rhinoviruses and metapneumovirus. The proportion of RSV-associated bronchiolitis hospitalisations decreased by 20%-30%, while rhinovirus- and metapneumovirus-associated bronchiolitis cases increased by 10%-20%. The effectiveness of nirsevimab in preventing RSV-associated admissions was estimated to be approximately 70%.Conclusion: Nirsevimab immunisation significantly reduced RSV-associated bronchiolitis admissions, though an increase in rhinovirus- and metapneumovirus-associated cases was observed.","PeriodicalId":55562,"journal":{"name":"Acta Paediatrica","volume":" ","pages":""},"PeriodicalIF":2.4,"publicationDate":"2025-03-26","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143712252","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Recurrence Rate in Children With Arterial Ischemic Stroke: A Systematic Review. 儿童动脉缺血性脑卒中的复发率：一项系统综述。

IF 2.4 4区医学

Acta Paediatrica Pub Date : 2025-03-26 DOI: 10.1111/apa.70075

Jacob Bastrup, Thomas Truelsen, Julie Brix Bindslev, Christina Engel Hoei-Hansen

{"title":"Recurrence Rate in Children With Arterial Ischemic Stroke: A Systematic Review.","authors":"Jacob Bastrup, Thomas Truelsen, Julie Brix Bindslev, Christina Engel Hoei-Hansen","doi":"10.1111/apa.70075","DOIUrl":"https://doi.org/10.1111/apa.70075","url":null,"abstract":"Aim: We conducted a systematic review to examine the recurrence rate in children with arterial ischemic stroke, including the recurrence rate according to stroke aetiology.Methods: This systematic review was conducted in accordance with the Preferred Reporting Items for Systematic Reviews and Meta-analyses statement. PubMed and Embase were searched for English-language cohort studies published between 1 January 2000 and 19 January 2023, reporting the recurrence rate in children with AIS. Identified studies were screened by two researchers on title/abstract level and full-text level. The risk of bias was assessed using the modified Critical Appraisal Skills Programme checklist.Results: The search yielded 28 studies, including 5546 children and 684 neonates. The studies were from 14 different countries with two international cohorts. Reported recurrence rates ranged from 0.0% to 1.9% for neonatal cohorts and 1.1% to 51.9% for childhood cohorts. The median recurrence rate was 10.6% for childhood AIS cohorts. Arteriopathies represented a high-risk aetiology associated with recurrence rates of 0.0%-52.2% with a median recurrence rate of 21.8%.Conclusion: These findings indicated that subgroups of patients possess a higher recurrence risk than others. Differences between studies highlighted the need for systematic approaches to future research on predictors of recurrent AIS.","PeriodicalId":55562,"journal":{"name":"Acta Paediatrica","volume":" ","pages":""},"PeriodicalIF":2.4,"publicationDate":"2025-03-26","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143722618","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

First Immunisations as per UK Schedule in Extreme Preterm Infants-Are They That Scary? 根据英国时间表对极度早产儿进行首次免疫接种-他们有那么可怕吗？

IF 2.4 4区医学

Acta Paediatrica Pub Date : 2025-03-26 DOI: 10.1111/apa.70077

Elise Peever, Rishini Wanigasekara, Vennila Ponnusamy

引用次数: 0

A National Survey on Paediatric Gastroenterologists' Role in Caring for Anorectal Malformations and Hirschsprung's Disease. 全国儿科胃肠病学家在肛肠畸形和巨结肠病护理中的作用调查。

IF 2.4 4区医学

Acta Paediatrica Pub Date : 2025-03-25 DOI: 10.1111/apa.70076

Anders Telle Hoel, Charlotte Kristensen Knatten, Kristin Bjørnland

{"title":"A National Survey on Paediatric Gastroenterologists' Role in Caring for Anorectal Malformations and Hirschsprung's Disease.","authors":"Anders Telle Hoel, Charlotte Kristensen Knatten, Kristin Bjørnland","doi":"10.1111/apa.70076","DOIUrl":"https://doi.org/10.1111/apa.70076","url":null,"abstract":"Aim: Most paediatric surgeons regard themselves as crucial and responsible for the follow-up of patients with anorectal malformations (ARM) and Hirschsprung's disease (HD). In this study, we explored to what extent paediatric gastroenterologists (PG) want to be involved in the care, if they experienced any knowledge gaps, and how they preferred to increase their knowledge.Methods: All Norwegian paediatric departments received a questionnaire covering different aspects of follow-up of patients with ARM and HD. One PG was asked to answer on behalf of the department.Results: 13/18 (72%) departments answered, 6/6 (100%) university- and 7/12 (58%) regional hospitals. The PG strongly disagreed that paediatric surgeons should have main responsibility for the follow-up on HD and ARM patients. The PG regarded the information provided by paediatric surgeons on main diagnosis, associated anomalies and recommendations for paediatric follow-up as insufficient. The PG listed surgical treatment, bowel management and long-term outcomes as knowledge gaps, and preferred national paediatric guidelines and paediatric meetings as sources to increase knowledge.Conclusion: PG want more involvement in the follow-up of ARM and HD patients. To increase their knowledge, they recommend improved information from paediatric surgeons, national guidelines and a focus on ARM and HD at national paediatric meetings.","PeriodicalId":55562,"journal":{"name":"Acta Paediatrica","volume":" ","pages":""},"PeriodicalIF":2.4,"publicationDate":"2025-03-25","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143702180","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0