极早产儿的发育轨迹及其对常规神经发育随访的影响。

IF 2.1 4区 医学 Q1 PEDIATRICS
Acta Paediatrica Pub Date : 2025-09-24 DOI:10.1111/apa.70306
Nina Gande, Michael Bloching, Christoph Hochmayr, Anna Staudt, Ulrike Pupp Peglow, Ursula Kiechl-Kohlendorfer, Elke Griesmaier
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引用次数: 0

摘要

目的:我们旨在评估1-5岁纠正的极早产儿的纵向轨迹,并检查1岁和2岁时婴儿和(幼儿)发育贝利量表(BSI(T)D)的表现如何预测学龄前的认知结果。方法:对2011年至2018年因斯布鲁克医科大学收治的499例极早产儿进行评估。用BSID-II/BSITD-III测量1岁和2岁时的认知结果,5岁时评估全量表智商(IQ)。结果:在499名婴儿中,345名(69.1%)完成了所有三个时间点的评估。大多数人的认知结果正常:1年时为92.2%,2年时为80.3%,5年时为80.9%。2年评估比1年评估显示出更强的预测价值,无论是在5岁时识别认知延迟(2 = 46% vs. 36%)。结论:1年评估的预测价值有限,2年评估对学龄前儿童认知结局的预测更有效。1岁和2岁时的BSITD组合对学龄前儿童的预测效果最好。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
Developmental Trajectories of Very Preterm Infants and Implications for Routine Neurodevelopmental Follow-Up.

Aim: We aimed to assess a longitudinal trajectory of very preterm infants from corrected 1-5 years and examined how well performances on the Bayley Scales of Infant and (Toddler) Development (BSI(T)D) at 1 and 2 years predict cognitive outcome at preschool age.

Methods: From 2011 to 2018, 499 very preterm infants admitted to the Medical University of Innsbruck were assessed. Cognitive outcomes at 1 and 2 years were measured with BSID-II/BSITD-III, and at 5 years, full scale intelligence quotient (IQ) was evaluated.

Results: Of the 499 infants, 345 (69.1%) completed assessments at all three time points. Most had normal cognitive outcomes: 92.2% at 1 year, 80.3% at 2 years and 80.9% at 5 years. The 2-year assessment demonstrated a stronger predictive value than the 1-year assessment, both for identifying cognitive delay at 5 years (< 85 points; AUC 0.88 vs. 0.77) and for predicting full-scale IQ scores in linear regression models (R2 = 46% vs. 36%).

Conclusion: The 1-year assessment had limited predictive value, whereas the 2-year assessment more effectively predicted preschool cognitive outcomes. A combination of BSITD at 1 and 2 years gave the best prediction at preschool age.

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来源期刊
Acta Paediatrica
Acta Paediatrica 医学-小儿科
CiteScore
6.50
自引率
5.30%
发文量
384
审稿时长
2-4 weeks
期刊介绍: Acta Paediatrica is a peer-reviewed monthly journal at the forefront of international pediatric research. It covers both clinical and experimental research in all areas of pediatrics including: neonatal medicine developmental medicine adolescent medicine child health and environment psychosomatic pediatrics child health in developing countries
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