AdiccionesPub Date : 2023-09-01DOI: 10.20882/adicciones.1694
Manuel Isorna, Francisco Pascual, Ester Aso, Francisco Arias
{"title":"Impact of the legalisation of recreational cannabis use.","authors":"Manuel Isorna, Francisco Pascual, Ester Aso, Francisco Arias","doi":"10.20882/adicciones.1694","DOIUrl":"https://doi.org/10.20882/adicciones.1694","url":null,"abstract":"<p><p>In recent years, there have been important legislative changes in many countries regarding the use of cannabis for medicinal and/or recreational purposes, which have facilitated access to it. Uruguay, Canada and some of the US states are the only jurisdictions that have legalised recreational consumption, applying different legislative models. The aim of this review is to analyse the effects that the legalisation of recreational cannabis has had on its use and its consequences. In general, the evidence accumulated to date indicates that the legalisation of cannabis has been associated with a decrease in the price of the substance, higher concentration of THC (potency), greater diversity of presentations for consumption, lower risk perception and an increase in consumption in adults and moderately in adolescents (even though it is illegal for them to consume), as well as an increase in the adverse consequences derived from cannabis consumption on public health. There has been a decrease in drug-related arrests, but the illegal market continues to be frequently used. No increase in the demand for treatment due to cannabis consumption has been detected. Therefore, these legislative changes have so far failed to achieve their main objectives, which were to suppress the illegal market and protect the most vulnerable groups, while on the contrary, they seem to imply an increase in some of the negative aspects associated with cannabis consumption. However, taking into account that most of these legislative changes have entered into force relatively recently, a longer follow-up period is required to be able to draw definitive conclusions.</p>","PeriodicalId":55560,"journal":{"name":"Adicciones","volume":"35 3","pages":"349-376"},"PeriodicalIF":3.0,"publicationDate":"2023-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"49694259","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
AdiccionesPub Date : 2023-09-01DOI: 10.20882/adicciones.1630
Inmaculada Santos-Álvarez, Pilar Pérez-Lloret, Juncal González-Soriano, Manuel Pérez-Moreno
{"title":"An approach to the evaluation of the potency of cannabis resin in Madrid: A health hazard?","authors":"Inmaculada Santos-Álvarez, Pilar Pérez-Lloret, Juncal González-Soriano, Manuel Pérez-Moreno","doi":"10.20882/adicciones.1630","DOIUrl":"10.20882/adicciones.1630","url":null,"abstract":"<p><p>The present study investigates the concentration of Delta (9)-tetrahidrocannabinol (THC), cannabidiol (CBD) and cannabinol (CBN) in 60 samples of cannabis resin acquired on the streets of Madrid region and its potential danger to consumers' health. Additionally, we study the possible correlation between the potency of samples and their organoleptic characteristics. The analysis of cannabinoids was carried out using a high performance liquid chromatography (RP-HPLC-UV). To classify samples, a strength scale based on THC content was established. THC content in 76.7% of the samples was higher than 15%. This potency allows these samples to be classified as Schedule I or drugs with \"unacceptable risk\" for human health. THC content in 36.7% of the samples was 28.8% on average, which means very high potency. The mean CBD content was 5%, while the correlation between the CBD/THC ratio and potency was negative. The mean content of CBN was 1.74% and the CBN/THC ratio also showed a negative correlation in respect to potency. When investigating the possible correlation between sample potency and organoleptic characteristics, those samples which simultaneously presented sticky texture, high elasticity and light brown colour had very high potency, with an average THC content of 28.7%. Our study shows that the THC content of most of the cannabis that can be purchased in Madrid region is over 15% and poses a health hazard. Additionally, we demonstrate for the first time that only those samples with very high potency can be directly associated with certain organoleptic characteristics.</p>","PeriodicalId":55560,"journal":{"name":"Adicciones","volume":"0 0","pages":"279-288"},"PeriodicalIF":3.0,"publicationDate":"2023-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"25528282","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
AdiccionesPub Date : 2023-09-01DOI: 10.20882/adicciones.1550
Rafael Aleixandre-Benavent, Víctor Agulló-Calatayud, Adolfo Alonso-Arroyo, Francisco-Jesús Bueno-Cañigral, Lourdes Castelló-Cogollos, Rut Lucas-Domínguez, David Melero-Fuentes, Andrea Sixto-Costoya, Antonio Vidal-Infer, Juan-Carlos Valderrama-Zurián
{"title":"Financed research from Government Delegation grants for the National Plan on Drugs: Research assessment and scientific impact.","authors":"Rafael Aleixandre-Benavent, Víctor Agulló-Calatayud, Adolfo Alonso-Arroyo, Francisco-Jesús Bueno-Cañigral, Lourdes Castelló-Cogollos, Rut Lucas-Domínguez, David Melero-Fuentes, Andrea Sixto-Costoya, Antonio Vidal-Infer, Juan-Carlos Valderrama-Zurián","doi":"10.20882/adicciones.1550","DOIUrl":"10.20882/adicciones.1550","url":null,"abstract":"<p><p>Addictive disorders are a serious health problem to which large amounts of research resources are devoted. This study aims to analyze the evolution and scientific impact of the publications derived from the funding of research projects by the Spanish National Plan on Drugs (PNSD). The list of grants awarded was provided by the PNSD. Derived publications were obtained by asking the principal investigators of the grants and searching in the Web of Science and Scopus. Bibliometric indicators and evolutive trends of scientific production per project were calculated. On average, the PNSD conferred 15 annual grants to research projects, with an annual amount close to one million euros (€944,200.64) and an average amount per grant of just over €60,000, being higher in basic research and in alcohol. 71,9% of the grants had derived publications and almost half of them produced between one and three publications, with basic research being the most prolific. The international journal in which most articles were published was Psychopharmacology (50) and among Spanish journals, Adicciones stood out (28). A high level of co-authorship and international collaboration was identified. Most of the PNSD-funded projects produced research articles, many of them in journals belonging to the first and second quartiles of the Journal Citation Reports. The results of this study have revealed the scientific impact of the PNSD research projects funding and may contribute to determining future funding priorities.</p>","PeriodicalId":55560,"journal":{"name":"Adicciones","volume":"0 0","pages":"249-264"},"PeriodicalIF":3.0,"publicationDate":"2023-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"25528278","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
AdiccionesPub Date : 2023-07-01DOI: 10.20882/adicciones.1680
Beltrán Jiménez-Fernández, Cristina Calomarde-Gómez, Ana López-Lazcano, Anna Lligoña, Antoni Gual, Hugo López-Pelayo
{"title":"Systematic review on the clinical management of chronic pain and comorbid opioid use disorder.","authors":"Beltrán Jiménez-Fernández, Cristina Calomarde-Gómez, Ana López-Lazcano, Anna Lligoña, Antoni Gual, Hugo López-Pelayo","doi":"10.20882/adicciones.1680","DOIUrl":"https://doi.org/10.20882/adicciones.1680","url":null,"abstract":"<p><p>The crisis caused by prescribed opioids and their related side effects are a public health problem worldwide. Most of these are prescribed for coping with chronic pain. The coexistence of opioid use disorder (OUD) in patients with chronic pain represents a complex challenge due to the need for managing both pain and OUD. The aim of this systematic review is to evaluate the efficacy of feasible treatments for this population with OUD and comorbid chronic pain for both conditions. A systematic database search has been performed using Cochrane Library, MEDLINE, PsycINFO and ClinicalTrials.gov in compliance with PRISMA guidelines. Eligible articles addressed the outcomes in chronic pain patients with comorbid opioid use disorder after treatment interventions were applied. Of 593 identified articles, nine were eligible for qualitative review (n = 7 pharmacological interventions; n = 2 psychological interventions). Methadone, buprenorphine, cognitive-behavioral and mindfulness showed promising results, but data were inconclusive (<2 RCT with low risk of bias). It is unclear whether the opioid agonist treatment should be maintained or tapered and which drug should be prescribed for the opioid substitution therapy (methadone or buprenorphine/naloxone). Mindfulness and cognitive behavioral therapy have a discrete effect on improving negative affect but not pain. The therapeutic approach might be individualized under a shared decision-making basis.</p>","PeriodicalId":55560,"journal":{"name":"Adicciones","volume":"35 2","pages":"197-212"},"PeriodicalIF":3.0,"publicationDate":"2023-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"10160596","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
AdiccionesPub Date : 2023-07-01DOI: 10.20882/adicciones.1291
Julia Cambra Almerge, Sergio Sánchez-Romero, Francisco Arias Horcajadas
{"title":"Differences between substance-induced psychotic disorders and non-substance-induced psychotic disorders and diagnostic stability.","authors":"Julia Cambra Almerge, Sergio Sánchez-Romero, Francisco Arias Horcajadas","doi":"10.20882/adicciones.1291","DOIUrl":"https://doi.org/10.20882/adicciones.1291","url":null,"abstract":"<p><p>Several hypotheses have been proposed to explain the comorbidity between psychotic disorders and substance use, one of them being the capacity of some to induce psychotic symptoms, although the transition from psychotic episodes induced by substances to schizophrenia has been less studied. In this study, differential variables between patients with induced and non-induced psychosis are determined, and the evolution and change of diagnosis of those induced to schizophrenia in the follow-up is analyzed. This is an observational case-control study with 238 patients admitted to the acute care unit for psychotic episodes between December 2003 and September 2011. The group of non-substance-induced psychotic disorders (NSIPD) included 127 patients, with 111 in the substance-induced (SIPD) group, according to the International Classification of Diseases. Sociodemographic and clinical characteristics, personal and family history, substance use, diagnostic stability and progression were compared. The NSIPD group showed higher scores in severity and in negative symptoms and more family history of psychosis. The SIPD group presented more personal history of personality disorder and family history of addictions and more positive symptoms At 6 years of follow-up, 40.9% of ISDP changed to a diagnosis of schizophrenia, presenting more family history of psychotic disorders and worse progression with more visits to the emergency department and readmissions, than subjects who maintained diagnostic stability. Therefore, special attention should be paid to this group of patients because of the potential severity and the increased risk of developing a chronic psychotic disorder.</p>","PeriodicalId":55560,"journal":{"name":"Adicciones","volume":"35 2","pages":"95-106"},"PeriodicalIF":3.0,"publicationDate":"2023-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"9845347","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
AdiccionesPub Date : 2023-07-01DOI: 10.20882/adicciones.1494
Juan Manuel Machimbarrena, Marta Beranuy, Esperanza Vergara-Moragues, Liria Fernández-González, Esther Calvete, Joaquín González-Cabrera
{"title":"Problematic Internet use and Internet gaming disorder: Overlap and relationship with health-related quality of life in adolescents.","authors":"Juan Manuel Machimbarrena, Marta Beranuy, Esperanza Vergara-Moragues, Liria Fernández-González, Esther Calvete, Joaquín González-Cabrera","doi":"10.20882/adicciones.1494","DOIUrl":"https://doi.org/10.20882/adicciones.1494","url":null,"abstract":"<p><p>General Problematic Internet Use (GPIU) is a dysfunctional use of Internet handling and management in general. In contrast, Internet Gaming Disorder (IGD) is a specific behaviour linked to online videogames. Both problems are becoming common in adolescents, but they have hardly been studied simultaneously, and the joint relationship of the two constructs with Health-Related Quality of Life (HRQoL) is unknown. The general objective of this study is to analyse the relationship between GPIU and IGD and their association with HRQoL. The study is analytical and cross-sectional with 2,024 participants (46.4% boys, n = 939) from 16 schools of 7 Spanish regions. The mean age and standard deviation were 14.20±1.42, with a range of 11-18 years. The Spanish versions of the KIDSCREEN-10, the Revised Generalized and Problematic Internet Use Scale 2 and the Internet Gaming Disorder Scale were used. Of the total sample evaluated, 15.5% of the participants had high levels of GPIU, and 3.3% of video game players presented IGD. The dimensions of GPIU are strongly associated with those of IGD. HRQoL correlated significantly and negatively with all the dimensions of GPIU and IGD (p <.001). Participants who reported problems with GPIU or IGD, individually or conjointly, had significantly lower scores in HRQoL than those with no problems.</p>","PeriodicalId":55560,"journal":{"name":"Adicciones","volume":"35 2","pages":"107-118"},"PeriodicalIF":3.0,"publicationDate":"2023-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"10143732","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
AdiccionesPub Date : 2023-07-01DOI: 10.20882/adicciones.1941
Mariano Chóliz Montañés
{"title":"On the issue of unconstitutionality raised by the Supreme Court regarding gambling advertising.","authors":"Mariano Chóliz Montañés","doi":"10.20882/adicciones.1941","DOIUrl":"https://doi.org/10.20882/adicciones.1941","url":null,"abstract":"","PeriodicalId":55560,"journal":{"name":"Adicciones","volume":"35 2","pages":"91-94"},"PeriodicalIF":3.0,"publicationDate":"2023-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"9948941","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Self-reported increase in alcohol and drugs intake as a coping strategy in hospital workers during COVID-19 outbreak: A cross-sectional study.","authors":"Agustín Madoz-Gúrpide, Mónica Leira-Sanmartín, Ángela Ibañez, Enriqueta Ochoa-Mangado","doi":"10.20882/adicciones.1643","DOIUrl":"https://doi.org/10.20882/adicciones.1643","url":null,"abstract":"<p><p>Situations of psychological stress, such as the current COVID-19 pandemic, could lead to an increase in the consumption of alcohol and other drugs of abuse as an inadequate coping strategy in health workers. This study aimed to investigate the intake of alcohol and drugs of abuse in hospital workers during the first wave of COVID-19. A further focus was to define the worker profile most vulnerable to this behavior through a logistic regression analysis. A cross-sectional study in a tertiary hospital in Madrid, Spain, during the first wave of COVID-19 was designed. Information was collected from a sample (n = 657) of healthcare workers (n = 536) and non-healthcare workers (n = 121). An online survey (including questions about basic health habits, working environment conditions, sociodemographic data, and the 12-item version of the General Health Questionnaire as a measure of psychological well-being) was conducted. Increased consumption of alcohol and/or drugs of abuse during the analyzed period of the pandemic was reported by 17.1% of workers. The following variables were associated with a higher probability of increased consumption of alcohol and/or drugs of abuse: male gender (p = .044), living alone or without dependents (p = .005), staff physician or resident (p = .010), having worked on the COVID frontline (p = .058), poor nutritional habits (p = .004) and self-prescription of psychotropic drugs to manage anxiety and insomnia (p = .003). A significant percentage of hospital workers increased their consumption of alcohol and drugs of abuse during the first wave of the COVID-19 pandemic. A professional risk profile can be defined for this practice.</p>","PeriodicalId":55560,"journal":{"name":"Adicciones","volume":"35 2","pages":"143-150"},"PeriodicalIF":3.0,"publicationDate":"2023-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"9784525","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
AdiccionesPub Date : 2023-07-01DOI: 10.20882/adicciones.1510
Lucía Moure-Rodríguez, Carina Carbia, Montserrat Corral Varela, Ainara Díaz-Geada, Fernando Cadaveira, Francisco Caamaño-Isorna
{"title":"Percepción del consumo de alcohol propio y de allegados en universitarios de primer curso como predictor del consumo a 10 años.","authors":"Lucía Moure-Rodríguez, Carina Carbia, Montserrat Corral Varela, Ainara Díaz-Geada, Fernando Cadaveira, Francisco Caamaño-Isorna","doi":"10.20882/adicciones.1510","DOIUrl":"https://doi.org/10.20882/adicciones.1510","url":null,"abstract":"<p><p>The alcohol use perceptions young people have of those close to them can affect their expectations regarding alcohol and, thus, their own drinking. We aim to identify the predictive ability of own and significant others' perceived drinking at age 18-19 in the alcohol use patterns at 27-28. A cohort study was carried out among university students in Spain (n=1,382). Binge Drinking (BD) and Risky Consumption (RC) were measured with the Alcohol Use Disorders Identification Test at ages 18, 20, 22, 24 and 27. Multilevel logistic regression for repeated measures was used to calculate the adjusted Odds Ratios (ORs). College students perceive their family's alcohol consumption as very low or nothing, while the perception of their own alcohol use or that of their friends is higher. Perceiving higher alcohol use among their siblings and friends increases the risk of BD for both sexes and RC for women. Living away from the parental home increases the risk of RC and BD. In conclusion, the perception of their friend's alcohol use at age 18-19 is the most influential variable in BD among both sexes and in RC among men throughout 10 years of follow-up. Parental alcohol consumption does not affect college student drinking patterns when friends and siblings are considered. Living with one's family acts as a protective factor. Preventive measures focused on young people should take a contextual approach and include those closest to them.</p>","PeriodicalId":55560,"journal":{"name":"Adicciones","volume":"35 2","pages":"119-134"},"PeriodicalIF":3.0,"publicationDate":"2023-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"10158541","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
AdiccionesPub Date : 2023-07-01DOI: 10.20882/adicciones.1612
Marta Donat, Luis Sordo, María José Belza, Juan Hoyos, Enrique Regidor, Gregorio Barrio
{"title":"Evolution of mortality attributable to alcohol in Spain according to age, sex, cause of death and type of drinker (2001-2017).","authors":"Marta Donat, Luis Sordo, María José Belza, Juan Hoyos, Enrique Regidor, Gregorio Barrio","doi":"10.20882/adicciones.1612","DOIUrl":"https://doi.org/10.20882/adicciones.1612","url":null,"abstract":"<p><p>There are no recent estimates of alcohol-attributable mortality in Spain with Spanish alcohol consumption data. The objective is to estimate it and know its evolution between 2001 and 2017 in people ≥15 years, according to sex, age, period, cause of death and type of drinker. The cause-specific approach and Levin's equation were used. Survey consumption was corrected for underestimation with respect to sales statistics, and past consumption and binge drinking were considered. The average annual number of deaths attributable to alcohol in 2010-2017 was 14,927, 58.6% of which were premature (<75 years). The age-standardized alcohol-attributable mortality rate was 39.4/100,000 inhabitants, representing 3.9% of overall mortality. Using standardized percentages, 68.7% corresponded to heavy drinkers. The most frequent causes of alcohol-attributable mortality were cancer (44.7%) and digestive diseases (33.2%). The rate of alcohol-attributable mortality was 3.5 times higher in men than in women (with higher ratios for young people and external causes). Between 2001-2009 and 2010-2017, the average annual rate decreased 16.8% (60.7% in 15-34 years; 19.4% in men and 9.8% in women). The contribution of heavy drinkers, digestive diseases and external causes to the risk of alcohol-attributable mortality decreased slightly between the two periods, while the contribution of cancer and circulatory diseases increased. These estimates are conservative. The contribution of alcohol to overall mortality is significant in Spain, requiring collective action to reduce it.</p>","PeriodicalId":55560,"journal":{"name":"Adicciones","volume":"35 2","pages":"165-176"},"PeriodicalIF":3.0,"publicationDate":"2023-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"9786067","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}