Differences between substance-induced psychotic disorders and non-substance-induced psychotic disorders and diagnostic stability.

IF 2.2 4区 医学 Q3 SUBSTANCE ABUSE
Julia Cambra Almerge, Sergio Sánchez-Romero, Francisco Arias Horcajadas
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引用次数: 1

Abstract

Several hypotheses have been proposed to explain the comorbidity between psychotic disorders and substance use, one of them being the capacity of some to induce psychotic symptoms, although the transition from psychotic episodes induced by substances to schizophrenia has been less studied. In this study, differential variables between patients with induced and non-induced psychosis are determined, and the evolution and change of diagnosis of those induced to schizophrenia in the follow-up is analyzed. This is an observational case-control study with 238 patients admitted to the acute care unit for psychotic episodes between December 2003 and September 2011. The group of non-substance-induced psychotic disorders (NSIPD) included 127 patients, with 111 in the substance-induced (SIPD) group, according to the International Classification of Diseases. Sociodemographic and clinical characteristics, personal and family history, substance use, diagnostic stability and progression were compared. The NSIPD group showed higher scores in severity and in negative symptoms and more family history of psychosis. The SIPD group presented more personal history of personality disorder and family history of addictions and more positive symptoms At 6 years of follow-up, 40.9% of ISDP changed to a diagnosis of schizophrenia, presenting more family history of psychotic disorders and worse progression with more visits to the emergency department and readmissions, than subjects who maintained diagnostic stability. Therefore, special attention should be paid to this group of patients because of the potential severity and the increased risk of developing a chronic psychotic disorder.

物质诱发性精神障碍与非物质诱发性精神障碍的差异及诊断稳定性。
人们提出了几种假说来解释精神障碍和物质使用之间的共病,其中一种假说是一些物质诱发精神症状的能力,尽管从物质诱发的精神发作到精神分裂症的过渡研究较少。本研究确定诱发性和非诱发性精神分裂症患者的差异变量,并分析诱发性精神分裂症患者在随访中诊断的演变和变化。这是一项观察性病例对照研究,研究对象是2003年12月至2011年9月期间因精神病发作而入住急性护理病房的238例患者。根据《国际疾病分类》,非物质诱发性精神障碍(NSIPD)组包括127名患者,物质诱发性(SIPD)组有111名患者。比较社会人口学和临床特征、个人和家族史、药物使用、诊断稳定性和进展。NSIPD组在严重程度和阴性症状方面得分更高,并且有更多的精神病家族史。SIPD组表现出更多的个人人格障碍史和成瘾家族史以及更多的阳性症状,在6年的随访中,40.9%的ISDP转变为精神分裂症的诊断,表现出更多的精神障碍家族史,并且与保持诊断稳定的受试者相比,出现更多的急诊科就诊和再入院,病情进展更糟。因此,由于潜在的严重程度和发展为慢性精神障碍的风险增加,应特别注意这组患者。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
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来源期刊
Adicciones
Adicciones SUBSTANCE ABUSE-
CiteScore
4.00
自引率
10.00%
发文量
36
审稿时长
>12 weeks
期刊介绍: Adicciones publica artículos originales sobre el tratamiento, la prevención, estudios básicos y descriptivos en el campo de las adicciones, como son las drogas ilegales, el alcohol, el tabaco o cualquier otra adicción, procedentes de distintas disciplinas (medicina, psicología, investigación básica, investigación social, etc.). Todos los artículos son seleccionados después de pasar un proceso de revisión anónimo hecho por expertos en ese tema.
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