Asian Pacific Journal of Cancer Prevention最新文献

{"title":"Understanding the Role of Rho GTPase Activating Protein and Bone Marrow Kinase X: A Novel Target in Gastric Cancer Treatment.","authors":"Zakari Shaibu, Zhihong Chen, Fumeng Yang, Xiaofeng Xu, Yong Ji, Wei Zhu","doi":"10.31557/APJCP.2025.26.3.725","DOIUrl":"https://doi.org/10.31557/APJCP.2025.26.3.725","url":null,"abstract":"<p><strong>Objective: </strong>To review the role of Rho GTPase Activating Protein (ARHGAP) and Bone Marrow Kinase X (BMX) in the progression and development of gastric cancer (GC), and to highlight their potential as therapeutic targets.</p><p><strong>Method: </strong>A comprehensive literature review was conducted to assess current evidence regarding the involvement of ARHGAP and BMX in GC, focusing on their expression levels, association with prognosis, and impact on tumor behavior.</p><p><strong>Results: </strong>Current research indicates that both ARHGAP and BMX are up-regulated in GC tissues, correlating with poor prognosis and aggressive tumor characteristics. These findings suggest that they play significant roles in the mechanisms underlying GC progression.</p><p><strong>Conclusion: </strong>The evidence supports the critical involvement of ARHGAP and BMX in GC, suggesting their potential as therapeutic targets. Further research is essential to clarify the mechanisms by which these proteins influence gastric cancer progression and to evaluate their viability as targets for new therapeutic strategies.</p>","PeriodicalId":55451,"journal":{"name":"Asian Pacific Journal of Cancer Prevention","volume":"26 3","pages":"725-733"},"PeriodicalIF":0.0,"publicationDate":"2025-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143744491","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Effect of Exercise Therapy, Systemic Acupuncture and Silicon Oxide Tablets on Muscular Strength, Lymphedema, and Quality of Life in Breast Cancer Survivors: Randomized Clinical Trial.","authors":"Patricia Santolia Giron, Cinira Assad Simão Haddad, Samantha Karlla Lopes De Almeida Rizzi, Simone Elias, Afonso Celso Pinto Nazário, Gil Facina","doi":"10.31557/APJCP.2025.26.3.799","DOIUrl":"https://doi.org/10.31557/APJCP.2025.26.3.799","url":null,"abstract":"<p><strong>Objective: </strong>The purpose of this study was to compare the effectiveness of three different rehabilitation treatments (exercise therapy, acupuncture, and silicon oxide tablets (Stiper®) in women who have undergone breast cancer surgery. The study assessed the impact of these treatments on strength, lymphedema, and quality of life.</p><p><strong>Methods: </strong>The study included seventy-nine women who reported pain levels above 3 on the visual analog pain scale (VAS) and had undergone surgery more than 90 days prior. Group I received exercise therapy for 30 minutes, Group II received acupuncture for 30 minutes using predefined points, and Group III received acupuncture at the same points as Group II using silicon oxide instead of needles at the same points as Group II.</p><p><strong>Results: </strong>The results showed an improvement in upper limb muscle strength over time in all groups, except for abduction and internal rotation movements. During treatment, there was no increase in the number of patients with lymphedema, and there was no statistical difference between the groups. Nine out of the fifteen factors analyzed in the EORTC QLQ-C30 quality of life questionnaire showed significant differences between sessions. The factors that did not show significant differences between the three groups were Social Function, Nausea and Vomiting, Dyspnea, Loss of Appetite, Constipation, and Diarrhea.</p><p><strong>Conclusion: </strong>The rehabilitation of physical dysfunctions in women who survived breast cancer through exercise therapy, acupuncture, and silicon oxide tablets in upper limb muscle strength, lymphedema, and quality of life, proved to be effective, without difference between groups.</p>","PeriodicalId":55451,"journal":{"name":"Asian Pacific Journal of Cancer Prevention","volume":"26 3","pages":"799-808"},"PeriodicalIF":0.0,"publicationDate":"2025-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143744554","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Exploring The Prevalence of Telomerase Reverse Transcriptase Promoter Mutations in Bladder Cancer Patients and Their Correlation with Tumor Characteristics.","authors":"Hanan H Ramadhan, Omar F Abdul-Rasheed, Safaa A Mohssin Alhamedi, Safaa G Mezban","doi":"10.31557/APJCP.2025.26.3.1053","DOIUrl":"https://doi.org/10.31557/APJCP.2025.26.3.1053","url":null,"abstract":"<p><strong>Objective: </strong>This work aimed to find the incidence of TERT promoter mutations in a specific patient population and to analyze their association with various tumor characteristics.</p><p><strong>Methods: </strong>This study, conducted from April to November 2023, involved collecting 67 formalin-fixed, paraffin-embedded (FFPE) tissue samples from patients undergoing transurethral bladder resection or radical cystectomy at the Urology Department of Almawaddah Private Hospital, Basra, Iraq. The extraction of DNA was achieved through the use of purification Promega kits. TERT gene promoter mutations, C228T AND C250T were determined by Sanger sequencing using an automated DNA sequencer, by Macrogen Corporation - Korea.</p><p><strong>Result: </strong>Among 67 bladder cancer patients, valid pTERT molecular analysis was completed in 59 cases. Of these, 30 patients (50.85%) were found to have pTERT mutations. The most common mutation was C228T, identified in 70% (21/30) of cases, followed by C250T in 33.3% (10/30), with one patient exhibiting both mutations. No significant associations were found between TERT mutations and factors such as age, sex, or smoking status. However, these mutations were more frequently observed in low-grade tumors, occurring in 63.3% (19/30) of cases. Additionally, the prevalence of TERT mutations differed significantly between non-muscle-invasive bladder cancer (NMIBC) and muscle-invasive bladder cancer (MIBC), with mutations detected in 60.4% (26/42) of NMIBC cases and 23.5% (4/17) of MIBC cases (p = 0.027). Although a slight difference in mutation frequency was noted between newly diagnosed and recurrent tumors, it did not reach statistical significance.</p><p><strong>Conclusion: </strong>this study demonstrates a substantial prevalence of TERT promoter mutations particularly the C228T variant in bladder cancer, which was more frequently found in NMIBC compared to MIBC. No correlations were identified between TERT mutations and demographic factors such as age, sex, or smoking history.</p>","PeriodicalId":55451,"journal":{"name":"Asian Pacific Journal of Cancer Prevention","volume":"26 3","pages":"1053-1058"},"PeriodicalIF":0.0,"publicationDate":"2025-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143744391","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Counselling to Screening: Honing an Institutional Cervical Cancer Screening Program.","authors":"Latika Chawla, Shalini Rajaram, Ipshita Sahoo, Shilpa Panta, Ayush Heda, Anupama Bahadur, Amrita Gaurav, Rajlaxmi Mundhra, Kavita Khoiwal, Ravi Kajal, Jaya Chaturvedi","doi":"10.31557/APJCP.2025.26.3.785","DOIUrl":"https://doi.org/10.31557/APJCP.2025.26.3.785","url":null,"abstract":"<p><strong>Objective: </strong>Cervical cancer screening is an important tool in WHO's global strategy for cervical cancer elimination. The objective of the study was to suggest and study the impact of capacity building interventions to increase cervical cancer screening rates in women aged 30-49 years attending the gynecological OPD.</p><p><strong>Methods: </strong>As part of a multicentric study, qualitative research was carried out at a tertiary care institute (from September 2021 to June 2022) to gather information regarding the existing cervical cancer screening practices, analyze factors preventing universal screening, and develop troubleshooting strategies. A fishbone analysis was done to identify barriers to cervical cancer screening. Stepwise sequential implementation of seven Plan-Do-Study-Act (PDSA) cycles which included; doctors training, policy formation, dedicated counsellor and reminders on social network groups, OPD card stamps, reading and educational material, screening in all OPD rooms and finally establishment of dedicated screening room. The effect of each on counselling and screening of eligible women was noted.</p><p><strong>Results: </strong>With the implementation of these PDSA cycles, the rates of eligible women being screened increased from 10.6% at baseline to 44.8% at the end of the study period. The percentage of counselled women increased to 70% and it was observed that counselled women were more likely to get screened.</p><p><strong>Conclusion: </strong>Educating women about the importance of cervical cancer screening and the creation of a dedicated screening room were the two most important quality improvement interventions.</p>","PeriodicalId":55451,"journal":{"name":"Asian Pacific Journal of Cancer Prevention","volume":"26 3","pages":"785-789"},"PeriodicalIF":0.0,"publicationDate":"2025-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143744534","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Development and Characterization of Curcumin Loaded PEGylated Niosomal Nanoparticles: Potential Anti-Cancer Effect on Breast Cancer Cells through RFC Gene Expression.","authors":"Neda Iranpoor, Davoud Jafari-Gharabaghlou, Siham Abdulzehra, Mohammad Reza Dashti, Fatemeh Gorbanzadeh, Nosratollah Zarghami","doi":"10.31557/APJCP.2025.26.3.1017","DOIUrl":"https://doi.org/10.31557/APJCP.2025.26.3.1017","url":null,"abstract":"<p><strong>Background: </strong>Breast cancer is the second leading cause of cancer deaths among women. Recent studies emphasize the significant role of folate metabolic pathways in cancer progression. The Reduced Folate Carrier (RFC), a folate transporter in cell membranes, plays an essential role in transporting folate receptor-dependent drugs. Curcumin, a bioactive compound with anticancer and anti-inflammatory effects, is hindered by low stability and a short half-life. Niosomes are versatile nanoparticles that can deliver both hydrophilic and hydrophobic drugs.</p><p><strong>Objective: </strong>This study aims to evaluate the anticancer effects of curcumin-loaded niosomal nanoparticles, focusing on their impact on RFC, BAX, and BCL-2 gene expression in MDA-MB-231 breast cancer cells.</p><p><strong>Methods: </strong>Curcumin-loaded noisomal nanoparticles were synthesized by the thin-film hydration method. Then, the morphology, size, and physico-chemical nanoparticles were determined by FE-SEM, DLS, and FT-IR methods, respectively. The MTT results determined the cytotoxicity of free and nano-formulated curcumin; also, the gene expression of RFC, BCL-2, and BAX was evaluated using the Real-Time PCR method. Furthermore, apoptosis and cell cycle analysis were investigated by Flow cytometry.  Results: The results of the physicochemical characteristics of the nanoparticles showed that curcumin was appropriately loaded in niosomal NPs. The MTT results showed that curcumin loaded in niosomal NPs has a higher anti-proliferative effect than free curcumin. Real-time PCR results showed increased RFC and BAX gene expression and decreased BCL-2 gene expression; this change was more significant in the treatment with nano-formulated curcumin. The apoptosis and cell cycle analysis also confirmed that free and nano-formulated curcumin induces apoptosis and cell cycle arrest.  Conclusion: Overall, the results suggested that curcumin loaded in niosomal nanoparticles effectively improves the anticancer effect and could be a capable approach for treating breast cancer.</p>","PeriodicalId":55451,"journal":{"name":"Asian Pacific Journal of Cancer Prevention","volume":"26 3","pages":"1017-1026"},"PeriodicalIF":0.0,"publicationDate":"2025-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143744547","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"CORRECTION TO: The Inhibition Mechanism of Pancreatic Ductal Adenocarcinoma via LXR Receptors: A Multifaceted Approach Integrating Molecular Docking, Molecular Dynamics and Post-MD Inter- Molecular Contact Analysis.","authors":"","doi":"10.31557/APJCP.2025.26.3.1099","DOIUrl":"https://doi.org/10.31557/APJCP.2025.26.3.1099","url":null,"abstract":"","PeriodicalId":55451,"journal":{"name":"Asian Pacific Journal of Cancer Prevention","volume":"26 3","pages":"1099"},"PeriodicalIF":0.0,"publicationDate":"2025-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143744527","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Resveratrol-Induced Modulation of Key Genes and DNA Fragmentation in Chronic Myeloid Leukemia Cells.","authors":"Laith Alhawamdeh, Belal Almajali, Ali M Atoom, Hanan Kamel M Saad, Razan Madi, Hamid Ali Nagi Al-Jamal","doi":"10.31557/APJCP.2025.26.3.905","DOIUrl":"https://doi.org/10.31557/APJCP.2025.26.3.905","url":null,"abstract":"<p><strong>Objective: </strong>Chronic myeloid leukemia (CML) is a hematologic malignancy characterized by the BCR-ABL1 fusion gene, which drives the uncontrolled proliferation of myeloid cells. Despite advancements in treatment, resistance to conventional therapies remains a significant challenge. Resveratrol, a natural polyphenol, has garnered attention for its potential therapeutic properties, including its ability to modulate key genes and induce apoptosis in cancer cells. This study investigated the effects of resveratrol on apoptosis, cell cycle regulation, and DNA fragmentation in CML cells.</p><p><strong>Methods: </strong>K562 CML cells were treated with resveratrol, and their effects were analyzed through CCK-8 assay for cell viability, TUNEL assay for DNA fragmentation, and real-time PCR for gene expression. Key apoptotic genes (BCL-2, AIF, BAX) were assessed alongside survival-related genes (CASP3, PGC1α, Cyclin-D1, p53) to evaluate resveratrol's anti-proliferative and pro-apoptotic potential.</p><p><strong>Result: </strong>Resveratrol exhibited a time-dependent reduction in K562 cell viability, with IC₅₀ values decreasing from 282.2 µM at 24 hours to 107.1 µM and 102.4 µM at 48 and 72 hours, respectively. Apoptotic activity, assessed via the TUNEL assay, revealed significant DNA fragmentation in 55 ± 5% of treated cells, while control cells showed no fragmentation. Gene expression analysis demonstrated upregulation of pro-apoptotic genes, including BCL-2, AIF (p < 0.05), BAX (p < 0.01), and VDAC1 (4.5-fold, p < 0.001). Conversely, genes linked to cell survival and metabolism, such as CASP3, PGC1α, NDUFA9, Cyclin-D1, and p53, were slightly downregulated (p < 0.05), highlighting resveratrol's dual role in promoting apoptosis and inhibiting cell survival.</p><p><strong>Conclusion: </strong>These findings suggest that resveratrol exerts anti-proliferative and pro-apoptotic effects in CML cells by modulating key genes and induction of DNA fragmentation, highlighting its potential as a therapeutic agent for CML treatment.</p>","PeriodicalId":55451,"journal":{"name":"Asian Pacific Journal of Cancer Prevention","volume":"26 3","pages":"905-911"},"PeriodicalIF":0.0,"publicationDate":"2025-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143744450","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Behavioural and Social Drivers (BeSD) of HPV vaccination in Zimbabwe: A Rapid Scoping Review of Literature.","authors":"Denford Munyaradzi Chuma, Ransom Machacha, Alex O Adjagba, James January","doi":"10.31557/APJCP.2025.26.3.775","DOIUrl":"https://doi.org/10.31557/APJCP.2025.26.3.775","url":null,"abstract":"<p><strong>Background: </strong>Regardless of the World Health Organization's recommendation for human papillomavirus (HPV) vaccination, Zimbabwe still faces challenges in achieving optimal vaccination coverage among female adolescents and young adults.</p><p><strong>Objectives: </strong>This rapid scoping review of literature aims to identify the behavioural and social drivers (BeSD) influencing HPV vaccination uptake in Zimbabwe over the past ten-year period.</p><p><strong>Methods: </strong>A scoping review of published and grey literature from 2014 to 2024 was conducted. Data analysis was guided by theoretical frameworks.</p><p><strong>Eligibility criteria: </strong> English language published and grey literature relevant to public health, vaccination, and social and behavioural sciences from Zimbabwe from 2014 to 2024.</p><p><strong>Sources of evidence: </strong>Ministry of Health & Child Care archives, African Journals Online, PubMed, Google Scholar, Scopus, and Web of Science.</p><p><strong>Charting methods: </strong>Tables with author information, year of publication, and relevant findings were used to chart the results.</p><p><strong>Results: </strong>Twenty-eight articles and grey literature sources were included. Key themes encompassed knowledge and attitudes, costs, vaccine uptake, healthcare provider perspectives, and feasibility of delivery methods. High knowledge levels regarding HPV and vaccination coexisted with misinformation and fears, impacting uptake. Socioeconomic factors and religious beliefs influenced HPV vaccination decisions. School-based vaccination was deemed feasible but faced challenges such as misinformation. Communication strategies, including a \"Communication for Development\" (C4D) approach, were crucial for addressing barriers and fostering community engagement.</p><p><strong>Discussion: </strong>The findings align with numerous theoretical frameworks including the Health Belief Model, Theory of Planned Behaviour, and Social Ecological Model. Addressing barriers at multiple levels, promoting cultural competence, and integrating HPV vaccination into existing healthcare activities are recommended.</p><p><strong>Conclusion: </strong>To enhance HPV vaccination uptake in Zimbabwe, tailored health literacy campaigns, leveraging existing healthcare infrastructure, increased political commitment, and integration into national immunization programmes are crucial. Implementation should draw on existing policies and guidelines to ensure sustainability and equity in vaccination efforts.</p>","PeriodicalId":55451,"journal":{"name":"Asian Pacific Journal of Cancer Prevention","volume":"26 3","pages":"775-783"},"PeriodicalIF":0.0,"publicationDate":"2025-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143744506","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"CD 14 Expression in Urothelial Carcinoma of The Urinary Bladder (Histopathological and Immunohistochemical Study).","authors":"Nora T El-Zohery, Yousra R Shalaby, Ayman I Kasem, Rasha R Mostafa","doi":"10.31557/APJCP.2025.26.3.889","DOIUrl":"https://doi.org/10.31557/APJCP.2025.26.3.889","url":null,"abstract":"<p><strong>Background: </strong>Egypt has a significantly higher prevalence of cancer bladder than the rest of the world. CD-14 antigen is involved in Toll-like receptor-mediated signaling pathways in inflammatory tumor microenvironment which promote tumor development and proliferation. There have been few studies on CD14 antigen effect on urothelial carcinoma of the urinary bladder. This study  aimed to evaluate the role of CD14 in prognosis of uurothelial carcinoma of the urinary bladder and its association with the tumor progression.</p><p><strong>Material and methods: </strong>This retrospective cross-sectional study included fifty-one cases of urothelial carcinoma obtained either by cystoscopic biopsies or radical cystectomies. They were immunohistochemically stained using anti- CD14 antibody. Statistical correlations between CD14 expression and available clinicopathological data were done.</p><p><strong>Results: </strong>Positive immunoexpression of CD14 was noted in 84.3% of all cases, showing scores 1, 2 & 3 in 9.8%, 29.4%, and 45.1% of cases, respectively. While negative immunoexpression was noted in 15.7% of cases and was scored as 0. A statistically significant correlation was noticed between CD14 immunohistochemical expression and each of the tumor grade, pathological tumor stage, status of muscle invasion, and pathological lymph node stage (P value=0.045, 0.030, 0.001, and 0.008 respectively). However, no statistically significant correlation was noted between CD14 immunohistochemical expression and each of the two-year survival rates in radical cystectomy cases and the mortality rate after exclusion of the postoperative complications (P value = 0.114 & 0.156 respectively).</p><p><strong>Conclusion: </strong>The intensity of CD14 expression was weak and even lost in high-grade and late-stage urothelial bladder carcinoma cases, while low-grade urothelial carcinoma cases showed CD14 overexpression. Accordingly, the significance of therapeutic approaches targeting CD14 in high-grade and late-stage urothelial bladder carcinoma shall be questionable.</p>","PeriodicalId":55451,"journal":{"name":"Asian Pacific Journal of Cancer Prevention","volume":"26 3","pages":"889-897"},"PeriodicalIF":0.0,"publicationDate":"2025-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143744510","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"CORRECTION TO: The Inhibition of RXRα and RXRβ Receptors Provides Valuable Insights for Potential Prostate Cancer Treatment, in silico Molecular Docking and Molecular Dynamics Studies.","authors":"","doi":"10.31557/APJCP.2025.26.3.1100","DOIUrl":"https://doi.org/10.31557/APJCP.2025.26.3.1100","url":null,"abstract":"","PeriodicalId":55451,"journal":{"name":"Asian Pacific Journal of Cancer Prevention","volume":"26 3","pages":"1100"},"PeriodicalIF":0.0,"publicationDate":"2025-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143744530","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}