Brain Topography最新文献

{"title":"An Efficient Approach for Detection of Various Epileptic Waves Having Diverse Forms in Long Term EEG Based on Deep Learning.","authors":"Zeinab Oghabian, Reza Ghaderi, Mahmoud Mohammadi, Sedighe Nikbakht","doi":"10.1007/s10548-025-01111-4","DOIUrl":"10.1007/s10548-025-01111-4","url":null,"abstract":"<p><p>EEG is the most powerful tool for epilepsy discharge detection in brain. Visual evaluation is hard in long term monitoring EEG data as huge amount of data needs to be inspected. Considering the fast and efficient results from deep learning networks especially convolutional networks, and its capability for detection of complex epileptic wave forms, inspired us to evaluate YOLO network for spike detection solution.The most used versions of YOLO (V3, V4 and V7) were evaluated for various epileptic signals. The epileptic discharge wave-forms were first labeled to 9 different signal types, but classified to four group combinations based on their features. EEG data from 20 patients were used under guidance of expert epileptologist. The YOLO networks were all trained for four various class-grouping strategies. The most suitable network to recommend was found to be YOLO-V4, for all four classifying methods giving average sensitivity, specificity, and accuracy of 96.7, 94.3, and 92.8, respectively. YOLO networks have shown promising results in detection of epileptic signals, which by adding some extra measurements this can become a great assistant tool for epileptologists. In addition, besides YOLO's High speed and accuracy in detection of epileptic signals in EEG, it can classify these signals to different morphologies.</p>","PeriodicalId":55329,"journal":{"name":"Brain Topography","volume":"38 3","pages":"35"},"PeriodicalIF":2.3,"publicationDate":"2025-03-04","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143544581","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Does the Cortical-Depth Dependence of the Hemodynamic Response Function Differ Between Age Groups?","authors":"Luisa Raimondo, Jurjen Heij, Tomas Knapen, Jeroen C W Siero, Wietske van der Zwaag, Serge O Dumoulin","doi":"10.1007/s10548-025-01107-0","DOIUrl":"10.1007/s10548-025-01107-0","url":null,"abstract":"<p><p>Functional magnetic resonance imaging (fMRI) is a widely used tool to investigate the functional brain responses in living humans. Valid comparisons of fMRI results depend on consistency of the blood-oxygen-level-dependent (BOLD) hemodynamic response function (HRF). Although common statistical approaches assume a single HRF across the entire brain, the HRF differs across individuals, regions of the brain, and cortical depth. Here, we measure HRF properties in primary visual cortex (V1) using 7 T fMRI with ultra-high spatiotemporal resolution line-scanning (250 μm in laminar direction, sampled every 105 ms). Line-scanning allowed us to investigate age-related HRF changes as a function of cortical depth. Eleven young and eleven middle-aged healthy participants participated in the experiments. We estimated the HRFs using a smooth basis function deconvolution approach. We also compared the results with conventional resolutions. From these HRFs, we extracted properties related to response magnitude and temporal dynamics. The cortical depth dependent HRFs were similar to the HRFs extracted using conventional resolutions validating the cortical depth dependent approach. We found that the properties of the HRF in the two age groups are similar across cortical depth. In other words, the variance between participants is larger than the variance between age groups. This suggests that middle-aged individuals can participate in cortical depth dependent studies free of bias in HRF properties.</p>","PeriodicalId":55329,"journal":{"name":"Brain Topography","volume":"38 3","pages":"34"},"PeriodicalIF":2.3,"publicationDate":"2025-02-28","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11870980/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143525388","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Electroencephalogram (EEG) Based Fuzzy Logic and Spiking Neural Networks (FLSNN) for Advanced Multiple Neurological Disorder Diagnosis.","authors":"Shraddha Jain, Rajeev Srivastava","doi":"10.1007/s10548-025-01106-1","DOIUrl":"10.1007/s10548-025-01106-1","url":null,"abstract":"<p><p>Neurological disorders are a major global health concern that have a substantial impact on death rates and quality of life. accurately identifying a number of diseases Due to inherent data uncertainties and Electroencephalogram (EEG) pattern overlap, conventional EEG diagnosis methods frequently encounter difficulties. This paper proposes a novel framework that integrates FLSNN to enhance the accuracy and robustness of multiple neurological disorder disease detection from EEG signals. In multiple neurological disorders, the primary motivation is to overcome the limitations of existing methods that are unable to handle the complex and overlapping nature of EEG signals. The key aim is to provide a unified, automated solution for detecting multiple neurological disorders such as epilepsy, Parkinson's, Alzheimer's, schizophrenia, and stroke in a single framework. In the Fuzzy Logic and Spiking Neural Networks (FLSNN) framework, EEG data is preprocessed to eliminate noise and artifacts, while a fuzzy logic model is applied to handling uncertainties prior to applying spike neural networking to analyze the temporal and dynamics of the signals. Processes EEG data three times faster than traditional techniques. This framework achieves 97.46% accuracy in binary classification and 98.87% accuracy in multi-class classification, indicating increased efficiency. This research provides a significant advancement in the diagnosis of multiple neurological disorders using EEG and enhances both the quality and speed of diagnostics from the EEG signal and the advancement of AI-based medical diagnostics. at https://github.com/jainshraddha12/FLSNN , the source code will be available to the public.</p>","PeriodicalId":55329,"journal":{"name":"Brain Topography","volume":"38 3","pages":"33"},"PeriodicalIF":2.3,"publicationDate":"2025-02-24","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143484634","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Efficient Neural Network Classification of Parkinson's Disease and Schizophrenia Using Resting-State EEG Data.","authors":"Wenjing Xiong, Lin Ma, Haifeng Li","doi":"10.1007/s10548-025-01102-5","DOIUrl":"10.1007/s10548-025-01102-5","url":null,"abstract":"<p><p>Timely identification of Parkinson's disease and schizophrenia is crucial for the effective management and enhancement of patients' quality of life. The utilization of electroencephalogram (EEG) monitoring applications has proven instrumental in diagnosing various brain disorders. Prior research has predominantly relied on predefined knowledge of physiological alterations associated with different diseases, employing feature extraction to discern brain conditions. This study introduces SwiftBrainNet, a neural network designed for the classification of Parkinson's disease and schizophrenia using short resting-state EEG segments. SwiftBrainNet aims to minimize reliance on manual feature extraction, relying solely on short EEG segments. Functioning as a single-input, dual-output neural network, SwiftBrainNet incorporates a deep supervisory mechanism facilitated by an auxiliary decoder, which enhances its classification performance by guiding the network in extracting shallow features. Our study conducts a clinical application-oriented experiment that uses continuous multi-segment EEG voting classification. This experiment demonstrates a noticeable improvement in accuracy compared to leave-one-out cross-validation (LOOCV), especially when combined with our data augmentation techniques. These findings underscore the method's practical value in clinical settings, where continuous data frames and enhanced generalization across subjects can significantly improve diagnostic accuracy. Additionally, the high accuracy observed in subject-dependent classification with very short data segments suggests that SwiftBrainNet might capture subject-specific EEG patterns, which could be further explored to enhance disease-related feature learning. This paper provides new evidence supporting the use of short-term EEG data for neurodiagnostic applications, making SwiftBrainNet a promising tool for the early detection of neurological disorders.</p>","PeriodicalId":55329,"journal":{"name":"Brain Topography","volume":"38 3","pages":"32"},"PeriodicalIF":2.3,"publicationDate":"2025-02-17","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143441861","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Brain Dynamics of Speech Modes Encoding: Loud and Whispered Speech Versus Standard Speech.","authors":"Bryan Sanders, Monica Lancheros, Marion Bourqui, Marina Laganaro","doi":"10.1007/s10548-025-01108-z","DOIUrl":"10.1007/s10548-025-01108-z","url":null,"abstract":"<p><p>Loud speech and whispered speech are two distinct speech modes that are part of daily verbal exchanges, but that involve a different employment of the speech apparatus. However, a clear account of whether and when the motor speech (or phonetic) encoding of these speech modes differs from standard speech has not been provided yet. Here, we addressed this question using Electroencephalography (EEG)/Event related potential (ERP) approaches during a delayed production task to contrast the production of speech sequences (pseudowords) when speaking normally or under a specific speech mode: loud speech in experiment 1 and whispered speech in experiment 2. Behavioral results demonstrated that non-standard speech modes entail a behavioral encoding cost in terms of production latency. Standard speech and speech modes' ERPs were characterized by the same sequence of microstate maps, suggesting that the same brain processes are involved to produce speech under a specific speech mode. Only loud speech entailed electrophysiological modulations relative to standard speech in terms of waveform amplitudes but also temporal distribution and strength of neural recruitment of the same sequence of microstates during a large time window (from approximatively - 220 ms to - 100 ms) preceding the vocal onset. Alternatively, the electrophysiological activity of whispered speech was similar in nature to standard speech. On the whole, speech modes and standard speech seem to be encoded through the same brain processes but the degree of adjustments required seem to vary subsequently across speech modes.</p>","PeriodicalId":55329,"journal":{"name":"Brain Topography","volume":"38 2","pages":"31"},"PeriodicalIF":2.3,"publicationDate":"2025-02-15","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11829918/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143426666","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Impact of EEG Reference Schemes on Event-Related Potential Outcomes: A Corollary Discharge Study Using a Talk/Listen Paradigm.","authors":"Subham Samantaray, Nishant Goyal, Muralidharan Kesavan, Ganesan Venkatasubramanian, Anushree Bose, Umesh Shreekantiah, Vanteemar S Sreeraj, Manul Das, Justin Raj, Sujeet Kumar","doi":"10.1007/s10548-025-01103-4","DOIUrl":"10.1007/s10548-025-01103-4","url":null,"abstract":"<p><p>The selection of an appropriate virtual reference schema is pivotal in determining the outcomes of event-related potential (ERP) studies, particularly within the widely utilized Talk/Listen ERP paradigm, which is employed to non-invasively explore the corollary discharge phenomenon in the speech-auditory system. This research centers on examining the effects of prevalent EEG reference schemas-linked mastoids (LM), common average reference (CAR), and reference electrode standardization technique (REST)-through statistical analysis, statistical parametric scalp mapping (SPSM), and source localization techniques. Our ANOVA findings indicate significant main effects for both the reference and the experimental condition on the amplitude of N1 ERPs. Depending on the reference used, the polarity and amplitude of the N1 ERPs demonstrate systematic variations: LM is associated with pronounced frontocentral activity, whereas both CAR and REST exhibit patterns of frontocentral and occipitotemporal activity. The significance of SPSM results is confined to regions exhibiting prominent N1 activity for each reference schema. Source analysis provides corroborative evidence more aligned with the SPSM results for CAR and REST than for LM, suggesting that results under CAR and REST are more objective and reliable. Therefore, the CAR and REST reference are recommended for future studies involving Talk/Listen ERP paradigms.</p>","PeriodicalId":55329,"journal":{"name":"Brain Topography","volume":"38 2","pages":"30"},"PeriodicalIF":2.3,"publicationDate":"2025-02-12","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143400743","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Neurophysiological Markers of Auditory Verbal Hallucinations in Patients with Schizophrenia: An EEG Microstates Study.","authors":"Shaobing Li, Ruxin Hu, Huiming Yan, Lijun Chu, Yuying Qiu, Ying Gao, Meijuan Li, Jie Li","doi":"10.1007/s10548-025-01105-2","DOIUrl":"10.1007/s10548-025-01105-2","url":null,"abstract":"<p><p>Alterations in the temporal characteristics of EEG microstates in patients with schizophrenia (SCZ) have been repeatedly found in previous studies. Nevertheless, altered temporal characteristics of EEG microstates in auditory verbal hallucinations (AVHs) SCZ are still unknown. This study aimed to investigate whether SCZ patients with sAVHs exhibit abnormal EEG microstates. We analyzed high-density electroencephalography data that from 79 SCZ patients, including 38 severe AVHs patients (sAVH group), 17 moderate auditory verbal hallucinations patients (mid-AVH group), and 24 without auditory verbal hallucinations patients (non-AVH group). Microstates were compared between three groups. Microstate C exhibited significant differences in duration and coverage and microstate B exhibited significant differences in occurrence between patients with sAVHs and without AVHs. There was a significant negative correlation between the coverage in microstate C and the severity of sAVH. Microstate C in duration, microstate B in occurrence were efficient in detecting sAVH patients. The decreased class C microstates in duration and coverage and increased class B microstates in occurrence may contribute to the severity of symptoms in AVH patients. Furthermore, we have identified that microstates C could serve as potential neurophysiological markers for detecting AVHs in SCZ patients. These results can provide potential avenues for therapeutic intervention of AVHs.</p>","PeriodicalId":55329,"journal":{"name":"Brain Topography","volume":"38 2","pages":"29"},"PeriodicalIF":2.3,"publicationDate":"2025-02-07","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143371285","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Abnormal Alterations of the White Matter Structural Network in Patients with Herpes Zoster and Postherpetic Neuralgia.","authors":"Zihan Li, Lili Gu, Xiaofeng Jiang, Jiaqi Liu, Jiahao Li, Yangyang Xie, Jiaxin Xiong, Huiting Lv, Wanqing Zou, Suhong Qin, Jing Lu, Jian Jiang","doi":"10.1007/s10548-025-01104-3","DOIUrl":"10.1007/s10548-025-01104-3","url":null,"abstract":"<p><p>PHN is one of the most common clinical complications of herpes zoster (HZ), the pathogenesis of which is unclear and poorly treated clinically, and many studies now suggest that postherpetic neuralgia (PHN) pain may be related to central neurologic mechanisms. This study aimed to investigate the white matter structural networks and changes in the organization of the rich-club in HZ and PHN. Diffusion imaging (DTI) data from 89 PHN patients, 76 HZ patients, and 66 healthy controls (HCs) were used to construct corresponding structural networks. Using graph-theoretic analysis, changes in the overall and local characteristics of the structural networks and rich-club organization were analyzed, and their correlations with clinical scales were analyzed. Compared with HCs, PHN patients had reduced global efficiency (Eg), reduced local efficiency (Eloc), a reduced clustering coefficient (Cp), a longer characteristic path length (Lp), and reduced nodal efficiency (Ne) in several brain regions, including the right posterior cingulate gyrus, the right supraoccipital gyrus, the bilateral postcentral gyrus, and the right precuneus; HZ patients had reduced Eg, a longer Lp, and reduced right orbital frontalis suprachiasmatic Ne. Moreover, HZ and PHN patients showed a significant reduction in the strength of rich-club connections. Compared with HZ patients, the intensities of the rich-club and feeder connections were lower in the PHN patients. Moreover, the changes in the structural networks and rich-club organization topology indices of the patients in the HZ and PHN patients were significantly correlated with disease duration, pain scores, and emotional changes. The structural networks of HZ and PHN patients exhibited reduced network transmission efficiency and rich-club connectivity, possibly due to structural damage to the white matter, and this was more obvious in PHN patients. The rich-club connectivity of HZ patients showed incomplete compensation in the acute pain stage.</p>","PeriodicalId":55329,"journal":{"name":"Brain Topography","volume":"38 2","pages":"28"},"PeriodicalIF":2.3,"publicationDate":"2025-02-06","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143257361","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"How Interoception and the Insula Shape Mental Imagery and Aphantasia.","authors":"Juha Silvanto, Yoko Nagai","doi":"10.1007/s10548-025-01101-6","DOIUrl":"10.1007/s10548-025-01101-6","url":null,"abstract":"<p><p>A major question in cognitive neuroscience is understanding the neural basis of mental imagery, particularly in cases of its absence, known as aphantasia. While research in this field has focused on the role of sensory domains, we propose that the key to understanding imagery lies in the intertwining of sensory processing and autonomic responses. Interoception plays a crucial role in mental imagery by anchoring experiences in first-person physiological signals, providing a self-referential perspective, and grounding the imagery in the body while also enabling its emotional aspects. Moreover, interoception contributes to the sense of agency and volitional control, as well as body schema-hallmarks of voluntary mental imagery. Therefore, imagery should be approached as an integrated phenomenon that combines sensory-specific information with interoceptive signals. At the neural level, this process engages the insula and anterior cingulate cortex (ACC), regions vital for synthesizing information across cognitive, emotional, and physical domains, as well as for supporting self-awareness. From this perspective, aphantasia may reflect a suboptimal functioning of the insula/ACC, which can account for its associations with deficits in autobiographical memory, emotion perception, and conditions such as autism and dyspraxia.</p>","PeriodicalId":55329,"journal":{"name":"Brain Topography","volume":"38 2","pages":"27"},"PeriodicalIF":2.3,"publicationDate":"2025-02-06","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143257347","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"How does Independent Component Analysis Preprocessing Affect EEG Microstates?","authors":"Fiorenzo Artoni, Christoph M Michel","doi":"10.1007/s10548-024-01098-4","DOIUrl":"10.1007/s10548-024-01098-4","url":null,"abstract":"<p><p>Over recent years, electroencephalographic (EEG) microstates have been increasingly used to investigate, at a millisecond scale, the temporal dynamics of large-scale brain networks. By studying their topography and chronological sequence, microstates research has contributed to the understanding of the brain's functional organization at rest and its alteration in neurological or mental disorders. Artifact removal strategies, which differ from study to study, may alter microstates topographies and features, possibly reducing the generalizability and comparability of results across research groups. The aim of this work was therefore to test the reliability of the microstate extraction process and the stability of microstate features against different strategies of EEG data preprocessing with Independent Component Analysis (ICA) to remove artifacts embedded in the data. A normative resting state EEG dataset was used where subjects alternate eyes-open (EO) and eyes-closed (EC) periods. Four strategies were tested: (i) avoiding ICA preprocessing altogether, (ii) removing ocular artifacts only, (iii) removing all reliably identified physiological/non physiological artifacts, (iv) retaining only reliably identified brain ICs. Results show that skipping the removal of ocular artifacts affects the stability of microstate evaluation criteria, microstate topographies and greatly reduces the statistical power of EO/EC microstate features comparisons, however differences are not as prominent with more aggressive preprocessing. Provided a good-quality dataset is recorded, and ocular artifacts are removed, microstates topographies and features can capture brain-related physiological data and are robust to artifacts, independently of the level of preprocessing, paving the way to automatized microstate extraction pipelines.</p>","PeriodicalId":55329,"journal":{"name":"Brain Topography","volume":"38 2","pages":"26"},"PeriodicalIF":2.3,"publicationDate":"2025-02-04","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11794336/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143191082","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}