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Exercise-Induced MYC as an Epigenetic Reprogramming Factor That Combats Skeletal Muscle Aging. 运动诱导的 MYC 是一种表观遗传重编程因子，可对抗骨骼肌老化。
IF 4.9 2区 医学
Exercise and Sport Sciences Reviews Pub Date : 2024-04-01 Epub Date: 2024-02-23 DOI: 10.1249/JES.0000000000000333
Ronald G Jones, Ferdinand von Walden, Kevin A Murach
{"title":"Exercise-Induced MYC as an Epigenetic Reprogramming Factor That Combats Skeletal Muscle Aging.","authors":"Ronald G Jones, Ferdinand von Walden, Kevin A Murach","doi":"10.1249/JES.0000000000000333","DOIUrl":"10.1249/JES.0000000000000333","url":null,"abstract":"<p><p>Of the \"Yamanaka factors\" Oct3/4 , Sox2 , Klf4 , and c-Myc (OSKM), the transcription factor c-Myc ( Myc ) is the most responsive to exercise in skeletal muscle and is enriched within the muscle fiber. We hypothesize that the pulsatile induction of MYC protein after bouts of exercise can serve to epigenetically reprogram skeletal muscle toward a more resilient and functional state.</p>","PeriodicalId":55157,"journal":{"name":"Exercise and Sport Sciences Reviews","volume":" ","pages":"63-67"},"PeriodicalIF":4.9,"publicationDate":"2024-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10963142/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"139934352","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Sex Differences in Neuromuscular Aging: The Role of Sex Hormones. 神经肌肉老化的性别差异：性激素的作用。
IF 4.9 2区 医学
Exercise and Sport Sciences Reviews Pub Date : 2024-04-01 Epub Date: 2024-02-08 DOI: 10.1249/JES.0000000000000335
Jessica Piasecki, Jakob Škarabot, Padraig Spillane, Mathew Piasecki, Paul Ansdell
{"title":"Sex Differences in Neuromuscular Aging: The Role of Sex Hormones.","authors":"Jessica Piasecki, Jakob Škarabot, Padraig Spillane, Mathew Piasecki, Paul Ansdell","doi":"10.1249/JES.0000000000000335","DOIUrl":"10.1249/JES.0000000000000335","url":null,"abstract":"<p><p>Males and females experience different trajectories of neuromuscular function across the lifespan, with females demonstrating accelerated deconditioning in later life. We hypothesize that the menopause is a critical period in the female lifespan, during which the dramatic reduction in sex hormone concentrations negatively impacts synaptic input to the motoneuron pool, as well as motor unit discharge properties.</p>","PeriodicalId":55157,"journal":{"name":"Exercise and Sport Sciences Reviews","volume":" ","pages":"54-62"},"PeriodicalIF":4.9,"publicationDate":"2024-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"139704094","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Vascular Responses to Acute Induced Inflammation With Aging: Does Fitness Matter? 随着年龄增长，血管对急性炎症的反应：体质重要吗？
IF 4.9 2区 医学
Exercise and Sport Sciences Reviews Pub Date : 2024-04-01 Epub Date: 2024-02-16 DOI: 10.1249/JES.0000000000000334
Elizabeth C Lefferts, Sushant M Ranadive
{"title":"Vascular Responses to Acute Induced Inflammation With Aging: Does Fitness Matter?","authors":"Elizabeth C Lefferts, Sushant M Ranadive","doi":"10.1249/JES.0000000000000334","DOIUrl":"10.1249/JES.0000000000000334","url":null,"abstract":"<p><p>Acute inflammation impairs vascular function in an age-dependent manner and affects cardiovascular event risk. Regular aerobic exercise preserves vascular function with aging and potentially modifies how acute inflammation affects the vasculature. We hypothesize high cardiorespiratory fitness may accompany greater arterial responsiveness post-acute inflammation in older adults.</p>","PeriodicalId":55157,"journal":{"name":"Exercise and Sport Sciences Reviews","volume":" ","pages":"68-75"},"PeriodicalIF":4.9,"publicationDate":"2024-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"139914083","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
A Novel Conceptual Model for Human Heat Tolerance. 人类耐热性的新概念模型
IF 4.9 2区 医学
Exercise and Sport Sciences Reviews Pub Date : 2024-04-01 Epub Date: 2024-01-30 DOI: 10.1249/JES.0000000000000332
Thomas E Bernard, S Tony Wolf, W Larry Kenney
{"title":"A Novel Conceptual Model for Human Heat Tolerance.","authors":"Thomas E Bernard, S Tony Wolf, W Larry Kenney","doi":"10.1249/JES.0000000000000332","DOIUrl":"10.1249/JES.0000000000000332","url":null,"abstract":"<p><p>Human \"heat tolerance\" has no accepted definition or physiological underpinnings; rather, it is almost always discussed in relative or comparative terms. We propose to use environmental limits to heat balance accounting for metabolic rate and clothing, that is, the environments for which heat stress becomes uncompensable for a specified metabolic rate and clothing, as a novel metric for quantifying heat tolerance.</p>","PeriodicalId":55157,"journal":{"name":"Exercise and Sport Sciences Reviews","volume":" ","pages":"39-46"},"PeriodicalIF":4.9,"publicationDate":"2024-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10963138/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"139643447","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Translating In Vitro Models of Exercise in Human Muscle Cells: A Mitocentric View. 在人类肌肉细胞中转化体外运动模型：以有丝分裂为中心的观点
IF 4.9 2区 医学
Exercise and Sport Sciences Reviews Pub Date : 2024-01-01 Epub Date: 2023-11-13 DOI: 10.1249/JES.0000000000000330
Reichelle X Yeo, John Noone, Lauren M Sparks
{"title":"Translating In Vitro Models of Exercise in Human Muscle Cells: A Mitocentric View.","authors":"Reichelle X Yeo, John Noone, Lauren M Sparks","doi":"10.1249/JES.0000000000000330","DOIUrl":"10.1249/JES.0000000000000330","url":null,"abstract":"<p><p>Human skeletal muscle cell (HSkMC) models provide the opportunity to examine in vivo training-induced muscle-specific mitochondrial adaptations, additionally allowing for deeper interrogation into the effect of in vitro exercise models on myocellular mitochondrial quality and quantity. As such, this review will compare and contrast the effects of in vivo and in vitro models of exercise on mitochondrial adaptations in HSkMCs.</p>","PeriodicalId":55157,"journal":{"name":"Exercise and Sport Sciences Reviews","volume":"52 1","pages":"3-12"},"PeriodicalIF":4.9,"publicationDate":"2024-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"138833115","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
From the Editor. 编辑的话
IF 5.7 2区 医学
Exercise and Sport Sciences Reviews Pub Date : 2024-01-01 Epub Date: 2023-05-10 DOI: 10.1249/JES.0000000000000327
Sandra K Hunter
{"title":"From the Editor.","authors":"Sandra K Hunter","doi":"10.1249/JES.0000000000000327","DOIUrl":"https://doi.org/10.1249/JES.0000000000000327","url":null,"abstract":"","PeriodicalId":55157,"journal":{"name":"Exercise and Sport Sciences Reviews","volume":"52 1","pages":"1-2"},"PeriodicalIF":5.7,"publicationDate":"2024-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"138833113","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
The Interaction of Duchenne Muscular Dystrophy and Insulin Resistance. 杜兴氏肌肉萎缩症与胰岛素抵抗的相互作用
IF 4.9 2区 医学
Exercise and Sport Sciences Reviews Pub Date : 2024-01-01 Epub Date: 2023-10-05 DOI: 10.1249/JES.0000000000000328
Swathy Krishna, John C Quindry, Rudy J Valentine, Joshua T Selsby
{"title":"The Interaction of Duchenne Muscular Dystrophy and Insulin Resistance.","authors":"Swathy Krishna, John C Quindry, Rudy J Valentine, Joshua T Selsby","doi":"10.1249/JES.0000000000000328","DOIUrl":"10.1249/JES.0000000000000328","url":null,"abstract":"<p><p>Duchenne muscular dystrophy (DMD), caused by deficiency of functional dystrophin protein, is a fatal, progressive muscle disease that frequently includes metabolic dysregulation. Herein, we explore the physiologic consequences of dystrophin deficiency within the context of obesity and insulin resistance. We hypothesized that dystrophin deficiency increases the frequency of insulin resistance, and insulin resistance potentiates muscle pathology caused by dystrophin deficiency.</p>","PeriodicalId":55157,"journal":{"name":"Exercise and Sport Sciences Reviews","volume":"52 1","pages":"31-38"},"PeriodicalIF":4.9,"publicationDate":"2024-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"138833114","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Translating Physical Activity Intentions into Behavior: Reflective, Regulatory, and Reflexive Processes. 将体育锻炼意向转化为行为：反思、调节和反射过程。
IF 4.9 2区 医学
Exercise and Sport Sciences Reviews Pub Date : 2024-01-01 Epub Date: 2023-11-07 DOI: 10.1249/JES.0000000000000329
Ryan E Rhodes
{"title":"Translating Physical Activity Intentions into Behavior: Reflective, Regulatory, and Reflexive Processes.","authors":"Ryan E Rhodes","doi":"10.1249/JES.0000000000000329","DOIUrl":"10.1249/JES.0000000000000329","url":null,"abstract":"<p><p>The purpose of this article was to review predictors of the physical activity (PA) intention-behavior relationship. The review provides evidence for the hypothesis that reflective (consciously deliberated expectations of PA), regulatory (tactics used to enact intentions), and reflexive (stimulus-based associative motivation) processes represent independent determinants of translating PA intentions into action, yet differ in relative contribution across time and circumstance.</p>","PeriodicalId":55157,"journal":{"name":"Exercise and Sport Sciences Reviews","volume":"52 1","pages":"13-22"},"PeriodicalIF":4.9,"publicationDate":"2024-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"138833116","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Using Martial Arts Training as Exercise Therapy Can Benefit All Ages. 将武术训练作为运动疗法可使所有年龄段的人受益。
IF 4.9 2区 医学
Exercise and Sport Sciences Reviews Pub Date : 2024-01-01 Epub Date: 2023-09-08 DOI: 10.1249/JES.0000000000000326
Yao Sun, Roza Tabeshian, Hajer Mustafa, E Paul Zehr
{"title":"Using Martial Arts Training as Exercise Therapy Can Benefit All Ages.","authors":"Yao Sun, Roza Tabeshian, Hajer Mustafa, E Paul Zehr","doi":"10.1249/JES.0000000000000326","DOIUrl":"10.1249/JES.0000000000000326","url":null,"abstract":"<p><p>Martial arts training focuses on whole-body movement patterning, philosophy, interpersonal interactions, and functional self-defense. Such training has positive impacts on physical, psychological, and cognitive well-being in older adults and children with and without clinical conditions. We hypothesize that martial arts training can be delivered as a form of exercise therapy for people at all ages to enhance overall health.</p>","PeriodicalId":55157,"journal":{"name":"Exercise and Sport Sciences Reviews","volume":" ","pages":"23-30"},"PeriodicalIF":4.9,"publicationDate":"2024-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"10220576","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Low Response to Aerobic Training in Metabolic Disease: Role of Skeletal Muscle. 代谢性疾病患者对有氧训练的低反应：骨骼肌的作用。
IF 5.7 2区 医学
Exercise and Sport Sciences Reviews Pub Date : 2023-12-18 DOI: 10.1249/jes.0000000000000331
Rogerio Nogueira Soares, Sarah J Lessard
{"title":"Low Response to Aerobic Training in Metabolic Disease: Role of Skeletal Muscle.","authors":"Rogerio Nogueira Soares, Sarah J Lessard","doi":"10.1249/jes.0000000000000331","DOIUrl":"https://doi.org/10.1249/jes.0000000000000331","url":null,"abstract":"Aerobic exercise is established to increase cardiorespiratory fitness (CRF), which is linked to reduced morbidity and mortality. However, people with metabolic diseases such as type 1 and type 2 diabetes may be more likely to display blunted improvements in CRF with training. Here, we present evidence supporting the hypothesis that altered skeletal muscle signaling and remodeling may contribute to low CRF with metabolic disease.","PeriodicalId":55157,"journal":{"name":"Exercise and Sport Sciences Reviews","volume":"42 1","pages":""},"PeriodicalIF":5.7,"publicationDate":"2023-12-18","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"138816457","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
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