Fungal Genetics and Biology最新文献

{"title":"The sensor protein VdSLN1 is involved in regulating melanin biosynthesis and pathogenicity via MAPK pathway in Verticillium dahliae","authors":"XiaYu Wang ,&nbsp;JunJiao Li ,&nbsp;XiaoBin Ji ,&nbsp;Dan Wang ,&nbsp;ZhiQiang Kong ,&nbsp;XiaoFeng Dai ,&nbsp;JieYin Chen ,&nbsp;DanDan Zhang","doi":"10.1016/j.fgb.2025.103960","DOIUrl":"10.1016/j.fgb.2025.103960","url":null,"abstract":"<div><div>The vascular wilt fungus <em>Verticillium dahliae</em> is a destructive soil-borne pathogen that causes yield loss on various economically important crops. Membrane-spanning sensor protein SLN1 have been demonstrated to contribute to virulence in varying degrees among numerous devastating fungal pathogens. However, the biological function of SLN1 in <em>V. dahliae</em> remains unclear. In this study, we identified the membrane-spanning sensor protein encoding gene <em>VdSLN1</em> and it interacts physically with Vst50 and regulates the expression of MAPK module Vst50-Vst11-Vst7. The expression of <em>VdSLN1</em> was also positively regulated by the MAPK signaling pathways transmembrane-associated members <em>VdSho1</em> and <em>VdMsb2</em>, suggesting that the expression of <em>VdSLN1</em> is associated with <em>VdSho1</em> and <em>VdMsb2</em>. In addition, we found that VdSLN1, similar to VdSho1 and VdMsb2, is not required for <em>V. dahliae</em> vegetative growth and response to various abiotic stresses. While, Δ<em>VdSLN1</em> mutant exhibited slightly reduced ability to penetrate a cellophane membrane and melanin synthesis compared with the wild type strain. Further experiments indicate that VdSLN1, VdSho1 and VdMsb2 has an additive effect on the virulence, cellophane penetration and melanin biosynthesis and of <em>V. dahliae</em>. In short, VdSLN1, though not essential, plays a role in cellophane penetration, melanin biosynthesis, also contributes to the virulence, as the downstream factor of VdSho1 and VdMsb2.</div></div>","PeriodicalId":55135,"journal":{"name":"Fungal Genetics and Biology","volume":"176 ","pages":"Article 103960"},"PeriodicalIF":2.4,"publicationDate":"2025-02-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142958981","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"生物学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"New saga in Finland: The rise of Diplodia sapinea in Scots pine","authors":"Eeva Terhonen ,&nbsp;Tiina Ylioja ,&nbsp;Tuija Hytönen ,&nbsp;Katri Leino ,&nbsp;Linda Mutanen ,&nbsp;Markus Melin ,&nbsp;Eeva Vaahtera ,&nbsp;Suvi Sutela","doi":"10.1016/j.fgb.2024.103955","DOIUrl":"10.1016/j.fgb.2024.103955","url":null,"abstract":"<div><div>The intensity of fungal virulence is likely to increase in northern forests as climate change alters environmental conditions, favoring pathogen proliferation in existing ecosystems while also facilitating their expansion into new geographic areas. In Finland, <em>Diplodia sapinea</em>, the causal agent of disease called “Diplodia tip blight”, has emerged as a new pathogen within the past few years. To reveal the current distribution of the novel fungal pathogen, and the effect of temperature and rainfall on its distribution, we utilized citizen science for the detection and collection of symptomatic Scots pine (<em>Pinus sylvestris</em>) shoots. The Finnish culture collection of <em>D. sapinea</em> was initiated using in vitro cultured symptomatic samples, and selected strains were studied for their virulence and disease cycle. Furthermore, the mycobiome of selected symptomatic and asymptomatic Scots pine shoots was studied using amplicon sequencing and the presence of <em>D. sapinea</em> was confirmed with culturing, qPCR, and species-specific PCR. Based on over 500 Scots pine shoots testing positive for <em>D. sapinea</em>, the distribution of this fungal pathogen is concentrated along the coastal areas of Finland, extending up to 200 km inland from the coastline. The observed presence of <em>D. sapinea</em> followed the period of highest average temperatures recorded in Finland in 2023 and was also found to be related to less precipitation. The amplicon sequencing showed that abundance of <em>D. sapinea</em> was higher in the healthy tissues of symptomatic shoots compared to visually healthy shoots. Similarly, the abundance was higher in samples collected from coastal areas in Southwestern Finland, which are the most heavily impacted by this disease. Here, we show that the presence of <em>D</em>. <em>sapinea</em> is more extensive than previously assumed, and lastly illustrate the hypothesized disease cycle of the fungal pathogen in Finland based on observations made in the field from 2021 to 2024 and in vivo and in vitro studies.</div></div>","PeriodicalId":55135,"journal":{"name":"Fungal Genetics and Biology","volume":"176 ","pages":"Article 103955"},"PeriodicalIF":2.4,"publicationDate":"2025-02-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142873560","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"生物学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Exploring endophytic fungi from Cynodon dactylon: GC–MS profiling and biological activity","authors":"Aishwarya K. Kamunkar ,&nbsp;R. Nischitha","doi":"10.1016/j.fgb.2024.103959","DOIUrl":"10.1016/j.fgb.2024.103959","url":null,"abstract":"<div><div>The rapid decline of significant plant species due to deforestation and slow regrowth has endangered many trees that are crucial for producing life-saving medications. This dual crisis of conserving plant biodiversity while meeting pharmaceutical demands necessitates innovative solutions. Endophytic fungi, naturally occurring symbionts within plants, present an eco-friendly and economically viable alternative. These fungi can produce a wide range of bioactive compounds, offering a sustainable source of pharmaceuticals. This study investigated endophytic fungi isolated from the inflorescence, leaf, and culm of <em>Cynodon dactylon,</em> a perennial medicinal grass. The research involved the isolation of endophytic fungi on potato dextrose agar (PDA) and water agar (WA), extracting secondary metabolites, and performing antimicrobial and antioxidant assays and gas chromatography-mass spectroscopy (GC–MS) profiling. A total of 21 endophytic fungi were isolated, with species of <em>Alternaria</em>, <em>Aspergillus</em>, and <em>Cladosporium</em> being predominant. These fungi were identified through morphological and molecular (internal transcribed sequences-ITS) characterization. Based on factors such as fungal dominance and specificity, five fungi (<em>Aspergillus chevalieri</em>, <em>Aspergillus stellatus</em>, <em>Hypoxylon</em> sp., and <em>Xylaria apiculate</em>) were selected and they exhibited significant activity against plant pathogens (<em>Sclerotium rolfsii</em> and <em>Aspergillus niger</em>) and radical scavenging properties in DPPH assays. GC–MS analysis revealed over twenty bioactive compounds in each fungal extract. These findings underscore the potential of endophytic fungi as sustainable sources of novel pharmaceuticals and effective biocontrol agents, offering a promising approach to address the current ecological and medicinal challenges.</div></div>","PeriodicalId":55135,"journal":{"name":"Fungal Genetics and Biology","volume":"176 ","pages":"Article 103959"},"PeriodicalIF":2.4,"publicationDate":"2025-02-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142904040","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"生物学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"FungANI, a BLAST-based program for analyzing average nucleotide identity (ANI) between two fungal genomes, enables easy fungal species delimitation","authors":"Christophe Lalanne ,&nbsp;Philippe Silar","doi":"10.1016/j.fgb.2025.103969","DOIUrl":"10.1016/j.fgb.2025.103969","url":null,"abstract":"<div><div>Fungal species delimitation and phylogeny will likely rely in the future upon whole genome sequence comparison, as the costs of such sequences are rapidly decreasing. <u>A</u>verage <u>N</u>ucleotide <u>I</u>dentity (ANI) between genomes is a convenient metric that can be rapidly calculated for species delimitation. However, there is presently no easy-to-use program calculating the ANI between two fungal genomes and providing easy-to interpret results that can be help mycologists having limited access to bioinformatic facilities. Here, we present FungANI, a customizable BLAST-based program that calculate ANI between genomes. The program primarily targets Linux workstations or servers but it can be run on the latest Windows, macOS and Linux 64-Bit operating systems as a standalone desktop application. It was tested with various publicly-available genomes from species belonging to the <em>Sordariales</em> order. It proved efficient to differentiate closely related species and retrace their possible phylogenetic relationships. However, FungANI did not perform well for phylogenetic reconstruction on a broader evolutionary scale such as inferring relationships between distant genera. The program is freely available at <span><span>https://github.com/podo-gec/fungani</span><svg><path></path></svg></span>.</div></div>","PeriodicalId":55135,"journal":{"name":"Fungal Genetics and Biology","volume":"177 ","pages":"Article 103969"},"PeriodicalIF":2.4,"publicationDate":"2025-01-31","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143082239","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"生物学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Physical forces supporting hyphal growth","authors":"Nicholas P. Money","doi":"10.1016/j.fgb.2025.103961","DOIUrl":"10.1016/j.fgb.2025.103961","url":null,"abstract":"<div><div>Hyphae are viscoelastic tubes whose internal pressure pushes the cell membrane against the inner surface of the cell wall. Catalytic yielding of the wall allows this turgor to force its polymers apart as new materials are added to the surface of the growing tip. Turgor drops slightly as the wall expands, creating a pressure gradient that causes the cytoplasm to flow toward the tip. These physiological processes affect the rate of extension of the hypha and determine the magnitude of the force that it uses for invasive growth. This paper provides an overview of the experimental basis for this description of hyphal mechanics and explains the wider significance of biophysical studies on fungi and water molds.</div></div>","PeriodicalId":55135,"journal":{"name":"Fungal Genetics and Biology","volume":"177 ","pages":"Article 103961"},"PeriodicalIF":2.4,"publicationDate":"2025-01-27","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143047521","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"生物学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Efficient genome editing using CRISPR/Cas9 technology and its application for identifying Sesquiterpene synthases involved in the biosynthesis of Steperoxides in Steccherinum ochraceum","authors":"Jia-Yu Shen ,&nbsp;Fei-Hong Mao ,&nbsp;Qiwen Wang ,&nbsp;Pei-Pei Ou ,&nbsp;Ji-Kai Liu ,&nbsp;Qunfei Zhao ,&nbsp;Qing-Li He","doi":"10.1016/j.fgb.2024.103944","DOIUrl":"10.1016/j.fgb.2024.103944","url":null,"abstract":"<div><div>CRISPR technology has been widely used for gene editing in various species，but the genetic manipulation in basidiomycete mushrooms is still notoriously difficult for unknown endogenous promoters and inefficient DNA delivery. <em>Steccherinum ochraceum</em> is a white rot basidiomycete fungus with abundant secondary metabolites and plays an important ecological role worldwide. To facilitate the study of gene function in <em>S. ochraceum</em>, an effective CRISPR/Cas9 system was successfully developed by identifying highly efficient endogenous promoters, and utilizing the <em>Agrobacterium</em>-transformation method. Two efficient endogenous RNA polymerase II promoters (P<em>sogpd</em> and P<em>sotef1</em>) and one efficient RNA polymerase III promoter (P<em>u6-d</em>) were identified and characterized, with an editing efficiency of 61.5 % at the <em>ura3</em> locus. Using this optimized system, the sesquiterpene gene <em>A0064</em>, which could produce 10 possible sesquiterpenes in the heterologous expression system of <em>A. oryzae</em>, was knocked out to obtain <em>A0064</em> knockout strain <em>S. ochraceum</em> (∆A0064). Steperoxide A could not be detected in <em>S. ochraceum</em> (∆A0064), demonstrating that A0064 was the only enzyme responsible for the biosynthesis of β-chamigrene (the sesquiterpene skeleton of steperoxide A) in <em>S. ochraceum</em>. This efficient system will enable precise targeting and multiplex editing of <em>S. ochraceum</em> genes, facilitating functional studies of genes involved in lignin degradation and natural product biosynthesis in <em>S. ochraceum</em>, and providing some valuable guidance for gene editing in tens of thousands of macrofungi.</div></div>","PeriodicalId":55135,"journal":{"name":"Fungal Genetics and Biology","volume":"175 ","pages":"Article 103944"},"PeriodicalIF":2.4,"publicationDate":"2024-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142734851","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"生物学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Physiological function of hydrophobin Hydph16 in cell wall formation in agaricomycete Pleurotus ostreatus","authors":"Junxian Han ,&nbsp;Moriyuki Kawauchi ,&nbsp;Yuki Terauchi ,&nbsp;Kenya Tsuji ,&nbsp;Akira Yoshimi ,&nbsp;Chihiro Tanaka ,&nbsp;Takehito Nakazawa ,&nbsp;Yoichi Honda","doi":"10.1016/j.fgb.2024.103943","DOIUrl":"10.1016/j.fgb.2024.103943","url":null,"abstract":"<div><div>Hydrophobins are small-secreted proteins with both hydrophobic and hydrophilic regions, enabling the mycelium to break through the air-medium interface by reducing the medium surface tension. Over 20 putative hydrophobin-encoding genes have been predicted in the agaricomycete <em>Pleurotus ostreatus</em>. Three hydrophobin-encoding genes, <em>vmh2</em>, <em>vmh3</em>, and <em>hydph1</em>6, were predominantly expressed in the vegetative mycelium. Despite these common properties, we have previously demonstrated the distinct functions of Vmh2 and Vmh3 in environmental stress resistance. In this study, we focused on <em>hydph16</em> and found that Δ<em>hydph16</em> strains had sparser aerial mycelium than control strains. The cell wall thickness of Δ<em>hydph16</em> strains reduced by 40 % compared to that of control strains, but no significant differences were found in the relative chitin and glucan percentages or relative putative cell wall synthesis-related gene expression levels. Furthermore, unlike <em>vmh2</em> and <em>vmh3</em>, <em>hydph16</em> deletion did not change the hydrophobicity of the aerial mycelium. This study is the first to report that the lack of hydrophobin can lead to a significant change in aerial hyphae cell wall formation without altering the major cell wall polysaccharide composition. Additionally, this study revealed multiple roles for Hydph16, distinct from those of other highly expressed hydrophobins, Vmh2 and Vmh3. These results suggested that agaricomycetes, including <em>P. ostreatu</em>s, have evolved to possess multiple hydrophobins with different functions.</div></div>","PeriodicalId":55135,"journal":{"name":"Fungal Genetics and Biology","volume":"176 ","pages":"Article 103943"},"PeriodicalIF":2.4,"publicationDate":"2024-11-28","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142755797","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"生物学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"The impact of glutamine synthetase PbgsA on the growth, conidiation and mycophenolic acid production of Penicillium brevicompactum","authors":"TingTing Hu ,&nbsp;Jishou Wu ,&nbsp;Zixuan Lin ,&nbsp;Yi Lin ,&nbsp;Lin Lin ,&nbsp;Wei Wei ,&nbsp;Dongzhi Wei","doi":"10.1016/j.fgb.2024.103941","DOIUrl":"10.1016/j.fgb.2024.103941","url":null,"abstract":"<div><div>Glutamine synthetase (GS) is a critical enzyme in nitrogen metabolism regulation and plays an essential role in the metabolic pathways involved in microbial growth and development. <em>Penicillium brevicompactum</em>, known for its rich repertoire of secondary metabolites, including mycophenolic acid (MPA), lacks research on the regulatory mechanisms of GS within this species. This study aimed to investigate the influence of GS on the growth, sporulation, and secondary metabolism of <em>P. brevicompactum</em> to elucidate the biological function of GS in this organism. We identified the glutamine synthetase gene (<em>PbgsA</em>) from <em>P. brevicompactum</em> and constructed <em>PbgsA</em> gene-overexpression and gene-silencing transformants. The impact of PbgsA on growth and sporulation was evaluated, revealing that <em>PbgsA</em> gene-overexpression transformants exhibited enhanced growth and significantly increased the expression levels of sporulation pathway genes (<em>brlA</em>, <em>abaA</em>, and <em>wetA</em>). Additionally, <em>PbgsA</em> gene-overexpression transformants produced higher MPA yields, with a maximum of 4.78 g/L, representing a 54.19 % increase compared to the wild type (WT). Conversely, <em>PbgsA</em> gene-silencing transformants showed reduced MPA production, with a minimum yield of 1.13 g/L, a 63.55 % decrease relative to the WT. Transcriptional analysis of the MPA biosynthetic gene cluster indicated that PbgsA exerted regulatory effects on certain biosynthetic pathway genes, such as <em>mpaA</em> and <em>mpaB</em>. This study demostrated the potential positive regulatory role of glutamine synthetase PbgsA in the growth, spore development, and secondary metabolism of <em>P. brevicompactum</em>, which provided a new strategy for genetic regulation in filamentous fungal.</div></div>","PeriodicalId":55135,"journal":{"name":"Fungal Genetics and Biology","volume":"175 ","pages":"Article 103941"},"PeriodicalIF":2.4,"publicationDate":"2024-11-16","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142669729","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"生物学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Screens for mutants defective in UapA trafficking highlight the importance of ER-exit as a primary control point in transporter biogenesis","authors":"Effie Demos ,&nbsp;Sofia Dimou ,&nbsp;Claudio Scazzocchio ,&nbsp;George Diallinas","doi":"10.1016/j.fgb.2024.103940","DOIUrl":"10.1016/j.fgb.2024.103940","url":null,"abstract":"<div><div>Most transmembrane membrane proteins are thought to traffic to the plasma membrane (PM) via the conventional secretory pathway through sorting from the Golgi. However, our recent work has shown that in the filamentous fungus <em>Aspergillus nidulans</em> several nutrient transporters and other major membrane proteins traffic to the PM via Golgi-bypass and independently of known post-Golgi secretory mechanisms. Here in an effort to dissect the molecular mechanism underlying membrane cargo trafficking via Golgi-bypass we design and use unbiased genetic screens, based on the UapA uric acid-xanthine transporter, which allowed the isolation of mutants defective in UapA translocation to the plasma membrane. Analyses of these mutants highlight the importance of ER-exit as the primary control point in transporter trafficking via Golgi-bypass. Most mutants isolated concerned mutations within the <em>uapA</em> gene, albeit we also obtained <em>uapA</em> extragenetic mutants affecting secretion and growth pleiotropically or leading on apparent activation of an efflux transporter related to purine-detoxification. Our work paves the way to use genetic approaches targeting specifically trafficking mutations affecting Golgi-bypass.</div></div>","PeriodicalId":55135,"journal":{"name":"Fungal Genetics and Biology","volume":"175 ","pages":"Article 103940"},"PeriodicalIF":2.4,"publicationDate":"2024-11-07","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142632912","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"生物学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Candida albicans strains adapted to the mouse gut are resistant to bile salts via a Flo8-dependent mechanism","authors":"Susana Hidalgo-Vico ,&nbsp;Daniel Prieto ,&nbsp;Rebeca Alonso-Monge ,&nbsp;Elvira Román ,&nbsp;Corinne Maufrais ,&nbsp;Christophe d’Enfert ,&nbsp;Jesús Pla","doi":"10.1016/j.fgb.2024.103939","DOIUrl":"10.1016/j.fgb.2024.103939","url":null,"abstract":"<div><div><em>Candida<!--> <!-->albicans</em> normally colonizes the human gastrointestinal tract as a commensal. Studying fungal factors involved in colonizing the mammalian gastrointestinal tract requires mouse models with altered microbiota. We have obtained strains of <em>C.<!--> <!-->albicans</em> through microevolution in the mouse gut for a prolonged period (one year) that display a substantial increase in fitness in this niche. These strains show resistance to bile salts, an increase in their adhesion to the intestinal mucosa, and are unable to filament in response to serum. Genetic analysis revealed some alterations, mainly a triploidy of chr7, a whole chr6 homozygosis, and an SNP in the <em>FLO8</em> gene (located in the chr6), resulting in a truncated protein version. A wild type <em>FLO8</em> gene complemented filamentation and bile salt sensitivity but showed an intermediate fitness phenotype in colonization. Alterations in bile salt sensitivity were also evident in <em>bmt</em> mutants, defective in β-mannosylation, and transcriptional targets of Flo8, suggesting a link between the fungal cell wall and mammalian gut colonization via the Flo8 transcriptional regulator.</div></div>","PeriodicalId":55135,"journal":{"name":"Fungal Genetics and Biology","volume":"175 ","pages":"Article 103939"},"PeriodicalIF":2.4,"publicationDate":"2024-10-31","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142565144","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"生物学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}