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Post-COVID-19 exaggerated exertional tachycardia: Relationship with pulmonary and cardiac sequelae covid -19后夸张的运动性心动过速:与肺和心脏后遗症的关系
IF 2.4 4区 医学
Heart & Lung Pub Date : 2025-06-06 DOI: 10.1016/j.hrtlng.2025.05.017
Giovanna Pelà , Annalisa Frizzelli , Roberta Pisi , Luigino Calzetta , Alessandra Marchese , Alfredo Chetta , Marina Aiello
{"title":"Post-COVID-19 exaggerated exertional tachycardia: Relationship with pulmonary and cardiac sequelae","authors":"Giovanna Pelà ,&nbsp;Annalisa Frizzelli ,&nbsp;Roberta Pisi ,&nbsp;Luigino Calzetta ,&nbsp;Alessandra Marchese ,&nbsp;Alfredo Chetta ,&nbsp;Marina Aiello","doi":"10.1016/j.hrtlng.2025.05.017","DOIUrl":"10.1016/j.hrtlng.2025.05.017","url":null,"abstract":"<div><h3>Background</h3><div>Long-COVID patients frequently complain of an Exaggerated Exertional Tachycardia (EET) and may represent a specific phenotype of post-COVID tachycardia syndrome. So far, no studies have investigated the factors contributing to EET.</div></div><div><h3>Objectives</h3><div>To determine the predictor factors of EET, seventy-nine Long-COVID-19 patients underwent comprehensive cardiologic and respiratory evaluations at follow-up visit after a median of 23 weeks from the acute phase of the disease. <em>Methods:</em> The heart rate (HR) response to exercise was assessed by the 6-minute walk test (6MWT), stratifying patients into two groups: EET and NET (normal exertional tachycardia). <em>Results:</em> The EET group was older, had higher body mass index and systolic blood pressure, with more comorbidities and lower resting HR, when compared to the NET group. The EET group also showed higher High-Resolution computed tomography scores and D-dimer levels during the acute phase compared to NET. At follow-up visit EET patients exhibited higher left ventricular mass and reduced systolic and diastolic function in both ventricles, as assessed by Doppler tissue echocardiography (myocardial S and E’ waves). We found a significant reduction in lung diffusion capacity and in mean oxygen saturation during the 6MWT in EET patients compared to NET ones. Stepwise logistic regression analysis identified the mean oxygen saturation during the 6MWT as the predictor of abnormal HR response to exercise.</div></div><div><h3>Conclusions</h3><div>We found that the exaggerated heart response to exercise in Long COVID-19 patients is associated to an impaired pulmonary function at rest and is predicted by the oxygen exercise-induced desaturation.</div></div>","PeriodicalId":55064,"journal":{"name":"Heart & Lung","volume":"73 ","pages":"Pages 228-235"},"PeriodicalIF":2.4,"publicationDate":"2025-06-06","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144229954","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Procalcitonin in acute exacerbation of interstitial lung disease: A systematic review of current evidence 降钙素原在间质性肺疾病急性加重中的作用:对现有证据的系统回顾
IF 2.4 4区 医学
Heart & Lung Pub Date : 2025-06-06 DOI: 10.1016/j.hrtlng.2025.05.014
Narat Srivali , Federica De Giacomi
{"title":"Procalcitonin in acute exacerbation of interstitial lung disease: A systematic review of current evidence","authors":"Narat Srivali ,&nbsp;Federica De Giacomi","doi":"10.1016/j.hrtlng.2025.05.014","DOIUrl":"10.1016/j.hrtlng.2025.05.014","url":null,"abstract":"<div><h3>Background</h3><div>Acute exacerbation of interstitial lung disease (AE-ILD) is a severe respiratory complication with overlapping clinical features that make distinguishing it from bacterial infections challenging.</div></div><div><h3>Objectives</h3><div>Evaluate procalcitonin's (PCT) diagnostic performance in differentiating AE-ILD from bacterial infections, focusing on sensitivity, specificity, and clinical applications.</div></div><div><h3>Methods</h3><div>Systematic literature review of Medline, Embase, and Cochrane Central databases through January 2025. Included clinical trials and observational studies assessing PCT levels in patients with interstitial lung disease experiencing acute respiratory decompensation, following PRISMA guidelines.</div></div><div><h3>Results</h3><div>Three studies involving 122 patients demonstrated consistent PCT diagnostic performance. Sensitivity ranged from 88.9 % to 95.5 %, specificity from 77.3 % to 100 %. Receiver operating characteristic analysis showed strong discriminatory power, with areas under the curve up to 0.85. Initial evidence suggested correlations between PCT levels and bacterial culture positivity and potential prognostic implications.</div></div><div><h3>Conclusions</h3><div>This first systematic review reveals promising diagnostic potential of PCT in AE-ILD, though current evidence is preliminary. While PCT appears effective in differentiating bacterial infections from non-infectious exacerbations, larger multicenter studies are needed to validate these findings and address identified knowledge gaps.</div></div>","PeriodicalId":55064,"journal":{"name":"Heart & Lung","volume":"73 ","pages":"Pages 221-227"},"PeriodicalIF":2.4,"publicationDate":"2025-06-06","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144221515","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Long-term effectiveness of SGLT2 inhibitors in type 2 diabetes patients with myocardial injury: A population-based study SGLT2抑制剂对2型糖尿病合并心肌损伤患者的长期疗效:一项基于人群的研究
IF 2.4 4区 医学
Heart & Lung Pub Date : 2025-06-06 DOI: 10.1016/j.hrtlng.2025.05.020
Matteo Ponzoni MD , Federico Rea PhD , Giovanni Corrao PhD , David J Barron MD , Anna Cantarutti PhD , Gabriella Morabito Msc
{"title":"Long-term effectiveness of SGLT2 inhibitors in type 2 diabetes patients with myocardial injury: A population-based study","authors":"Matteo Ponzoni MD ,&nbsp;Federico Rea PhD ,&nbsp;Giovanni Corrao PhD ,&nbsp;David J Barron MD ,&nbsp;Anna Cantarutti PhD ,&nbsp;Gabriella Morabito Msc","doi":"10.1016/j.hrtlng.2025.05.020","DOIUrl":"10.1016/j.hrtlng.2025.05.020","url":null,"abstract":"<div><h3>Background</h3><div>Sodium-glucose cotransporter 2 (SGLT2) inhibitors have demonstrated cardiovascular benefits in randomized trials. However, real-world evidence on their cardioprotective effect in high-risk populations with documented myocardial injury—such as heart failure (HF), acute coronary syndrome (ACS), myocardial revascularization, or cardiac surgery—is still limited.</div></div><div><h3>Objective</h3><div>To evaluate the impact of SGLT2 inhibitor adherence on cardiovascular outcomes in patients with type 2 diabetes mellitus (T2DM) and a history of myocardial injury, in a real-world setting.</div></div><div><h3>Methods</h3><div>We retrospectively reviewed the healthcare utilization databases of the Lombardy region (Italy) to identify all patients with T2DM who were dispensed SGLT2 inhibitors between 2014–2020, and had one hospitalization for HF, myocardial revascularization, ACS or cardiac surgery in the previous 10 years. Adherence was calculated as the proportion of days covered by therapy during follow-up. Cox regression analysis was performed to estimate the hazard ratios (HR) for cardiovascular hospitalizations and death.</div></div><div><h3>Results</h3><div>Among 1789 HF, 5759 revascularization, 3986 ACS, and 4580 cardiac surgery patients, higher adherence to SGLT2i therapy was consistently associated with a lower risk of CV events or death. Adjusted HRs for high vs. very low adherence were: HF, 0.65 (95 %CI:0.52–0.82); revascularization, 0.70 (95 %CI:0.59–0.84); ACS, 0.76 (95 %CI:0.62–0.93); and cardiac surgery, 0.69 (95 %CI:0.57–0.84). A dose-response trend was observed across adherence levels.</div></div><div><h3>Conclusion</h3><div>High adherence to SGLT2 inhibitors therapy can significantly decrease the risk of cardiovascular-related hospitalization and death in patients with T2DM and several forms of myocardial injury, such as HF, ACS, myocardial revascularization, and cardiac surgery.</div></div>","PeriodicalId":55064,"journal":{"name":"Heart & Lung","volume":"73 ","pages":"Pages 236-242"},"PeriodicalIF":2.4,"publicationDate":"2025-06-06","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144250880","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Fear of disease progression in patients after open-heart surgery: A cross-sectional study 心内直视手术后患者对疾病进展的恐惧:一项横断面研究
IF 2.4 4区 医学
Heart & Lung Pub Date : 2025-06-05 DOI: 10.1016/j.hrtlng.2025.05.018
Zilu Liang , Shaoyan Lin , Huimei Sun , Yingying Liao , Cuishan Chen , Muchen Zhang , Huijuan Song
{"title":"Fear of disease progression in patients after open-heart surgery: A cross-sectional study","authors":"Zilu Liang ,&nbsp;Shaoyan Lin ,&nbsp;Huimei Sun ,&nbsp;Yingying Liao ,&nbsp;Cuishan Chen ,&nbsp;Muchen Zhang ,&nbsp;Huijuan Song","doi":"10.1016/j.hrtlng.2025.05.018","DOIUrl":"10.1016/j.hrtlng.2025.05.018","url":null,"abstract":"<div><h3>Background</h3><div>Fear of disease progression (FoP) is an emerging issue in patients after open-heart surgery (OHS), but data on this phenomenon are scarce and require further investigation.</div></div><div><h3>Objectives</h3><div>This study aims to explore the current status of FoP in patients after OHS and to detect potential factors associated with FoP.</div></div><div><h3>Methods</h3><div>A cross-sectional design with convenience sampling was conducted on 210 patients who experienced OHS in the Department of Cardiovascular Surgery of a tertiary hospital in China from March 2024 to April 2025 by the demographic and clinical characteristics questionnaire, the Fear of Progression Questionnaire-Short Form, the Medical Coping Modes Questionnaire, the Social Support Rating Scale, the Brief Illness Perception Questionnaire, and the Hospital Anxiety and Depression Scale. Data were analyzed by using correlation analysis, univariate analysis, and multiple linear regression.</div></div><div><h3>Results</h3><div>The average score of FoP was 34.55 ± 6.34, with 94 patients (44.76 %) having clinically abnormal FoP levels (score ≥ 34). The results of multiple linear regression analysis showed that age, educational level, family history of CVD, number of disease episodes, postoperative complications, anxiety and depression, coping modes (confrontation and avoidance), social support, illness perception were factors influencing FoP, accounting for 75.20 % of the total variance.</div></div><div><h3>Conclusion</h3><div>FoP is a commonly observed issue among patients after OHS. It is necessary to develop specialized psychological interventions and tailored assistance based on patient-specific factors to reduce FoP.</div></div>","PeriodicalId":55064,"journal":{"name":"Heart & Lung","volume":"73 ","pages":"Pages 214-220"},"PeriodicalIF":2.4,"publicationDate":"2025-06-05","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144212085","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Association of albumin-bilirubin score with cardiovascular risk among adults in the US 美国成人白蛋白-胆红素评分与心血管风险的关系
IF 2.4 4区 医学
Heart & Lung Pub Date : 2025-06-04 DOI: 10.1016/j.hrtlng.2025.05.019
Tao Tang MD , Yu Feng MD , Aline M. Thomas PhD , Shen Li MD, PhD
{"title":"Association of albumin-bilirubin score with cardiovascular risk among adults in the US","authors":"Tao Tang MD ,&nbsp;Yu Feng MD ,&nbsp;Aline M. Thomas PhD ,&nbsp;Shen Li MD, PhD","doi":"10.1016/j.hrtlng.2025.05.019","DOIUrl":"10.1016/j.hrtlng.2025.05.019","url":null,"abstract":"<div><h3>Background</h3><div>Liver dysfunction plays a significant role in cardiovascular disease (CVD), yet it lacks effective and practical clinical biomarkers for CVD screening. Albumin-bilirubin (ALBI) score, a novel liver impairment biomarker, has demonstrated significant prognostic value in heart failure.</div></div><div><h3>Objective</h3><div>To evaluate the association between the ALBI score and cardiovascular risk.</div></div><div><h3>Methods</h3><div>This nationally representative study included adults 20 years or older in age from the National Health and Nutritional Examination Survey 2001–2018. ALBI score was calculated using the formula (log<sub>10</sub> bilirubin [umol/L] * 0.66 - 0.85 * albumin [g/dL]). Outcomes were CVD prevalence and mortality. Weighted multivariable regression analyses were performed to determine the associations between ALBI score and outcomes.</div></div><div><h3>Results</h3><div>Data for 43194 adults were analyzed. A total of 4923 CVD were initially identified, and 1878 CVD-related deaths occurred over an average follow-up period of 8.9 years. A per standard deviation higher ALBI score was associated with an elevated CVD prevalence (OR 1.18, 95 % CI 1.13–1.23) and mortality (HR 1.25, 95 % CI 1.17–1.33). The odds ratios for CVD prevalence comparing the second or highest tertile to the lowest tertile of ALBI scores were 1.12 (95 % CI 0.99–1.26) and 1.35 (95 % CI 1.21–1.51), respectively (<em>P</em> for trend &lt; 0.001). The corresponding hazard ratios for CVD mortality were 1.05 (95 % CI 0.88–1.26) and 1.31 (95 % CI 1.12–1.53), respectively (<em>P</em> for trend &lt; 0.001).</div></div><div><h3>Conclusions</h3><div>A higher ALBI score was associated with an increased risk of CVD prevalence and mortality among US adults. The ALBI score of liver dysfunction may serve as an effective marker for CVD risk stratification.</div></div>","PeriodicalId":55064,"journal":{"name":"Heart & Lung","volume":"73 ","pages":"Pages 207-213"},"PeriodicalIF":2.4,"publicationDate":"2025-06-04","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144212353","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Evolving Trends in Antihypertensive Therapy for Heritable Thoracic Aortic Disease:A 28-Year Retrospective Analysis 遗传性胸主动脉疾病降压治疗的发展趋势:28年回顾性分析
IF 2.4 4区 医学
Heart & Lung Pub Date : 2025-05-30 DOI: 10.1016/j.hrtlng.2025.04.015
Brittany D. Rhoades (she/her/hers) PhD, APRN, CCNS, CCTN, FCNS, Gilda E. Martinez (she/her/hers) MSN, APRN, FNP-C, Veronica Glover (she/her/hers) PhD, Susan Green (she/her/hers) MPH, Lynna Nguyen (she/her/hers) MSC, Marc R. Moon (he/him/his) MD, Joseph Coselli (he/him/his) MD
{"title":"Evolving Trends in Antihypertensive Therapy for Heritable Thoracic Aortic Disease:A 28-Year Retrospective Analysis","authors":"Brittany D. Rhoades (she/her/hers) PhD, APRN, CCNS, CCTN, FCNS,&nbsp;Gilda E. Martinez (she/her/hers) MSN, APRN, FNP-C,&nbsp;Veronica Glover (she/her/hers) PhD,&nbsp;Susan Green (she/her/hers) MPH,&nbsp;Lynna Nguyen (she/her/hers) MSC,&nbsp;Marc R. Moon (he/him/his) MD,&nbsp;Joseph Coselli (he/him/his) MD","doi":"10.1016/j.hrtlng.2025.04.015","DOIUrl":"10.1016/j.hrtlng.2025.04.015","url":null,"abstract":"&lt;div&gt;&lt;h3&gt;Background&lt;/h3&gt;&lt;div&gt;Aortic aneurysms, dissections, and ruptures rank as the 19th leading cause of death in the United States, contributing to nearly 50,000 fatalities annually. These conditions often remain silent until catastrophic events occur, underscoring the importance of early detection, including clinical and phenotypic recognition, and proactive management. In contrast to age-related abdominal aortic disease, 20% of thoracic aortic aneurysms are attributed to heritable thoracic aortic disease (HTAD). Typically, HTAD is identified in young patients by surviving an acute aortic event, detecting an incidental imaging finding or phenotypic concern, or investigating familial relationships.&lt;/div&gt;&lt;div&gt;Optimizing medical management of hypertension is essential for mitigating the progression of aortic disease and reducing the risk of dissection and rupture. Beta-blockers (BBs) and angiotensin II receptor blockers (ARBs), specifically Losartan, can decrease hemodynamic stress on the aortic wall, potentially slowing aneurysmal expansion and minimizing life-threatening events.&lt;/div&gt;&lt;/div&gt;&lt;div&gt;&lt;h3&gt;Aim&lt;/h3&gt;&lt;div&gt;This study aims to evaluate a 28-year trend in antihypertensive therapy among HTAD patients undergoing elective aortic repair at a robust aortic center in the Southwest.&lt;/div&gt;&lt;/div&gt;&lt;div&gt;&lt;h3&gt;Methods&lt;/h3&gt;&lt;div&gt;We included 990 HTAD patients ≥18 years (median age, 43 years; quartile 1-quartile 3, 36-49) who underwent elective aortic surgery within a high-volume practice in the Southwest United States (1996-2024). Patients were categorized into one of four groups based on antihypertensive medication regimen at the time of surgery: no medication (NoMeds, n=98), beta-blockers only (BBs only, n=675), angiotensin II receptor blockers only (ARBs only, n=70), or both BBs and ARBs (BBs+ARBs, n=147). Descriptive statistics and group comparisons were performed to retrospectively evaluate trends and outcomes.&lt;/div&gt;&lt;/div&gt;&lt;div&gt;&lt;h3&gt;Results&lt;/h3&gt;&lt;div&gt;Overall, most patients were male (68%, n=668), had hypertension (75%, n=744), and were ≤50 years of age (84%, n=827). Notably, nearly 10% of patients (n=98) were not receiving any antihypertensive medication. Over time, there has been a significant decline in the proportion of patients managed without antihypertensive therapy or with beta blockers (BBs) alone. Specifically, the use of BBs as monotherapy decreased by nearly 24% (p&lt; 0.01) as clinical practice evolved toward greater adoption of angiotensin receptor blockers (ARBs), either alone or in combination with BBs (Figure 1). This shift highlights advancements in evidence-based strategies for optimizing perioperative hypertensive medical management of HTAD patients (Figure 2).&lt;/div&gt;&lt;/div&gt;&lt;div&gt;&lt;h3&gt;Conclusions&lt;/h3&gt;&lt;div&gt;Managing hypertension is essential for reducing the risk of aortic disease progression, dissection, and rupture; beta-blockers (BBs) and angiotensin II receptor blockers (ARBs) are effective treatments. This analysis underscores significant ","PeriodicalId":55064,"journal":{"name":"Heart & Lung","volume":"72 ","pages":"Pages 98-99"},"PeriodicalIF":2.4,"publicationDate":"2025-05-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144170327","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Optimizing Volume in Ambulatory Heart Failure Patients: Beyond Oral Diuretics 优化门诊心力衰竭患者的容积:超越口服利尿剂
IF 2.4 4区 医学
Heart & Lung Pub Date : 2025-05-30 DOI: 10.1016/j.hrtlng.2025.04.016
Donna Moser BSN RN CHFN
{"title":"Optimizing Volume in Ambulatory Heart Failure Patients: Beyond Oral Diuretics","authors":"Donna Moser BSN RN CHFN","doi":"10.1016/j.hrtlng.2025.04.016","DOIUrl":"10.1016/j.hrtlng.2025.04.016","url":null,"abstract":"&lt;div&gt;&lt;h3&gt;Background&lt;/h3&gt;&lt;div&gt;Heart failure (HF) is a chronic, progressive disease that effects over 6 million Americans. Despite growing options in the Guideline Directed Medical Therapy and innovative technology, 25% may return to the hospital within 30 days for IV diuresis. This results in CMS financial penalties for the hospital and personal cost to the patient in reduced quality of life and mortality.&lt;/div&gt;&lt;/div&gt;&lt;div&gt;&lt;h3&gt;Aim&lt;/h3&gt;&lt;div&gt;The purpose of this study is to examine effectiveness of appropriate options for patients that may be resistant to standard oral diuretic volume management utilizing a nurse-run outpatient diuresis center and/or home diuresis with subcutaneous furosemide (Furoscix(R)).&lt;/div&gt;&lt;/div&gt;&lt;div&gt;&lt;h3&gt;Methods&lt;/h3&gt;&lt;div&gt;HF specialists and HF physician assistants (PAs) identify inpatient or outpatient HF clinic patients as volume overloaded and at high risk for readmission. Referral to the nurse-supervised Outpatient Diuresis Clinic by an order set is placed in the Electronic Medical Record for serial weekly infusions (Bumetanide 2 mg or Furosemide 80 mg IVP) with standard lab work (BMP, Magnesium level). After insurance authorization is determined, the appointment is scheduled. A hospital van service provides transportation within a 6-mile radius. When the patient arrives, they are provided a comfortable recliner in a private curtained area. Weight and vital signs are recorded, an IV access placed, and the IV diuretic given. HF provider or CHFN is notified by the infusion nurse if a patient is hypotensive, hypertensive or has a serious lab results requiring Emergency Department evaluation. Labs are reviewed after 2 hours. Oral potassium and magnesium are provided if needed per order set and IV access removed. If distance to the Outpatient Diuresis Center is prohibitive or the patient has difficulty ambulating, Furoscix(R) 80 mg subcutaneous is an effective option. Coverage by insurance is investigated, and the medication ordered through Furoscixdirect.com. Our patients and carepartners are instructed in application in clinic or a trained homecare nurse is ordered for application, clinical assessment and HF education in the home. The collaboration of the CHFN, the HF PAs and MDs with the Diuresis Center and homecare nurses is key to the success of this model.&lt;/div&gt;&lt;/div&gt;&lt;div&gt;&lt;h3&gt;Results&lt;/h3&gt;&lt;div&gt;Between Jan 2022 and November 2024, 74 men and 55 women with HF (N=129), age 30-91, with insurance (Medicare N=100, Medicaid N=24, Commercial N=5) were identified and agreed to Outpatient Diuresis. Thirty-six-point four percent (36.4% N=47) did not go to any Outpatient Diuresis sessions. Of these 47 patients, 36% (N=16) were readmitted in less than 30 days (Average 10.4 days). Adherent patients (63.6%. N=82) attended at least 1 to 4 weekly sessions. Only 6% (N=5) of these patients were readmitted within 30 days (Average 17.2 days). Average hospitalization-free time of the 82 adherent patients utilizing outpatient diuresis and/or Furoscix","PeriodicalId":55064,"journal":{"name":"Heart & Lung","volume":"72 ","pages":"Page 99"},"PeriodicalIF":2.4,"publicationDate":"2025-05-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144170626","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
The Impact of the GEtting iNTo Light Exercise for Heart Failure (GENTLE-HF) Randomized Controlled Trial on Physical-Psychological Outcomes and Exercise Adherence 轻度运动治疗心力衰竭(GENTLE-HF)随机对照试验对生理-心理结局和运动坚持性的影响
IF 2.4 4区 医学
Heart & Lung Pub Date : 2025-05-30 DOI: 10.1016/j.hrtlng.2025.04.017
Jane Kim (she/her/hers) BSN, RN
{"title":"The Impact of the GEtting iNTo Light Exercise for Heart Failure (GENTLE-HF) Randomized Controlled Trial on Physical-Psychological Outcomes and Exercise Adherence","authors":"Jane Kim (she/her/hers) BSN, RN","doi":"10.1016/j.hrtlng.2025.04.017","DOIUrl":"10.1016/j.hrtlng.2025.04.017","url":null,"abstract":"<div><h3>Background</h3><div>Exercise is recommended to improve the lives of patients with heart failure (HF), but numerous barriers prevent exercise engagement and long-term exercise adherence. Yoga has been studied as a complementary therapy for patients with HF. Small pilot studies show short-term benefits of yoga-like gentle exercise for individuals with HF. Few investigators have examined the effect of online yoga exercise interventions on long-term benefits and exercise adherence.</div></div><div><h3>Aim</h3><div>The study aims were to: 1) Evaluate the efficacy of a 6-month online yoga and educational intervention on physical and psychological function, 2) Evaluate whether age or sex moderated the efficacy of the intervention on physical function, and 3) Determine the relationship between quality of life scores and exercise adherence in patients with HF.</div></div><div><h3>Methods</h3><div>Data from the Getting iNTo Light Exercise for HF (GENTLE-HF) randomized control trial (n = 61) was analyzed. Measures included physical function (tests of flexibility, upper/lower body strength, agility, balance, endurance, waist circumference), psychological function (depression and anxiety), quality of life, and exercise adherence. A general linear ANCOVA-approach model was used to examine physical and psychological function, adjusting for age, years of education, baseline study scores, and grouping (control or intervention). Pearson correlation analysis was used to examine the relationship between baseline quality of life scores and yoga intervention adherence.</div></div><div><h3>Results</h3><div>Compared to control, the intervention group had improved upper body strength (p = .004), lower body strength (p = .002), and endurance (p = .003). Age moderated the effect of the intervention on upper body strength (p = .012) and endurance (p = .028). Psychological (depression and anxiety) function did not significantly differ between the groups. Adherence was high at 62.5%. Greater quality of life scores were associated with higher exercise adherence (p = .039).</div></div><div><h3>Conclusions</h3><div>The online yoga intervention led to significant improvements in upper/lower body strength and endurance among participants, had a stronger, additional effect for participants over 65 years, and had high adherence rates. The study also demonstrated that greater quality of life was associated with higher exercise adherence. Online exercise programs incorporating yoga can increase exercise accessibility and improve exercise adherence rates. The findings from this study can impact HF exercise guidelines with potential recommendations for gentle types of exercise, inform future large-scale yoga studies, and improve outcomes among patients with HF.</div></div>","PeriodicalId":55064,"journal":{"name":"Heart & Lung","volume":"72 ","pages":"Pages 100-101"},"PeriodicalIF":2.4,"publicationDate":"2025-05-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144170627","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Board of Directors 董事会
IF 2.4 4区 医学
Heart & Lung Pub Date : 2025-05-30 DOI: 10.1016/S0147-9563(25)00098-6
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引用次数: 0
The Effects of Exercise on Depression in Patients Diagnosed with Heart Failure with Preserved Ejection Fraction 运动对保留射血分数心力衰竭患者抑郁的影响
IF 2.4 4区 医学
Heart & Lung Pub Date : 2025-05-30 DOI: 10.1016/j.hrtlng.2025.04.014
Harrison L. Krebs (he/him/his) MSN, RN, CCRN, Marilyn A. Prasun PhD, CCNS, CNL, CHFN, FAHA, John Blakeman PhD, RN, PCCN, Annette Hubbell PhD, RN, Matthew Hesson-McInnis PhD
{"title":"The Effects of Exercise on Depression in Patients Diagnosed with Heart Failure with Preserved Ejection Fraction","authors":"Harrison L. Krebs (he/him/his) MSN, RN, CCRN,&nbsp;Marilyn A. Prasun PhD, CCNS, CNL, CHFN, FAHA,&nbsp;John Blakeman PhD, RN, PCCN,&nbsp;Annette Hubbell PhD, RN,&nbsp;Matthew Hesson-McInnis PhD","doi":"10.1016/j.hrtlng.2025.04.014","DOIUrl":"10.1016/j.hrtlng.2025.04.014","url":null,"abstract":"&lt;div&gt;&lt;h3&gt;Background&lt;/h3&gt;&lt;div&gt;Millions of Americans are living with heart failure in the United States, and about 50% of those individuals have a preserved ejection fraction (HFpEF). Many patients living with heart failure may deal with managing depression. Depression, combined with HFpEF, puts individuals at risk for increased mortality rates and hospital admissions—making the management of these diseases of the utmost importance. Exercise is recommended for individuals with HFpEF. However, exercise to manage depressive symptoms in individuals with HFpEF has yet to be fully explored.&lt;/div&gt;&lt;/div&gt;&lt;div&gt;&lt;h3&gt;Aim&lt;/h3&gt;&lt;div&gt;This systematic literature review aimed to examine the effects of exercise therapy on depression reported by individuals diagnosed with HFpEF.&lt;/div&gt;&lt;/div&gt;&lt;div&gt;&lt;h3&gt;Methods&lt;/h3&gt;&lt;div&gt;A systematic literature search was conducted following the Preferred Reporting Items for Systematic Reviews and Meta-Analyses (PRISMA) methodology in five electronic databases: SPORTDiscus, PubMed, Cumulative Index to Nursing and Allied Health Literature, Academic Search Complete, and the Joanna Briggs Institute Evidence-Based Practice Database, using specific terms for research studies published between 2010 and 2024. The Joanna Briggs Institute critical appraisal tool was used to assess the quality of the included studies. Inclusion criteria consisted of original human subjects’ peer-reviewed research, studies that enrolled adults diagnosed with HFpEF, studies using exercise as a form of treatment, studies published in the English language, and studies that used depression as an outcome measure. Exclusion criteria consisted of nonhuman subjects research, studies with participants younger than 18 years of age, studies that did not include patients with HFpHF, studies that did not use exercise as a treatment, studies that used no valid measure of depression, or incomplete studies.&lt;/div&gt;&lt;/div&gt;&lt;div&gt;&lt;h3&gt;Results&lt;/h3&gt;&lt;div&gt;Sixty-seven studies were identified, but only five (totaling 306 participants) met the inclusion criteria. Exercise therapy consisted of strength, endurance training, and Tai Chi. Depression was measured using various validated instruments: the Patient Health Questionnaire (PHQ-9), Geriatric Depression Scale-15, Profile of Mood States, and the Hare-Davis Cardiac Depression Scale. All five studies showed improved depression scores following exercise therapy, with four studies reporting statistically significant improvements. Depression scores improved significantly in four of the five included studies. Specifically, depression was reduced by 0.8 points (measured with the Geriatric Depression Scale-15), 2 points (measured with the PHQ-9 tool), 1.7 points (measured with the subscale of Depression in Profile of Mood State), and 3.95 points (measured with the PHQ-9) in these 4 studies. The fifth study demonstrated a 7-point improvement in depression (measured with the Hare-Davis Cardiac Depression Scale), though this change was not statistically sign","PeriodicalId":55064,"journal":{"name":"Heart & Lung","volume":"72 ","pages":"Pages 97-98"},"PeriodicalIF":2.4,"publicationDate":"2025-05-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144170625","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
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