Heart & Lung最新文献

{"title":"The association between posttraumatic stress symptoms and hope following intensive care unit discharge: Findings from a longitudinal cohort study.","authors":"Klara Friberg, Kristin Hofsø, Tone Rustøen, Johan Ræder, Milada Hagen, Kathleen Puntillo, Brita Fosser Olsen","doi":"10.1016/j.hrtlng.2024.12.003","DOIUrl":"https://doi.org/10.1016/j.hrtlng.2024.12.003","url":null,"abstract":"<p><strong>Background: </strong>Hope is essential for mental health in general and for recovery following severe illness. However, the associations between posttraumatic stress symptoms (PTSS) and hope among intensive care unit (ICU) survivors has not been investigated.</p><p><strong>Objectives: </strong>To assess hope at 3, 6 and 12 months after ICU admission and examine possible associations between hope and selected demographic data, clinical characteristics, and 3-month PTSS-levels among ICU patients.</p><p><strong>Methods: </strong>ICU-patients from Norway self-reported on hope using Herth Hope Index. Data on demographics and clinical characteristics were collected from patient reports and medical records. PTSS were analysed 3 months after admission, using descriptive statistics and linear mixed model regression analyses.</p><p><strong>Results: </strong>A total of 73 adult ICU survivors were included (male n = 45 (61.6%); median age 66 years [IQR: 51.0;74.0]). Median hope scores were 41, 40, and 42 at 3, 6 and 12 months, respectively. A clinically minor but statistically significant reduction in hope was registered at 6 months (B = -1.24; 95% confidence interval [CI]: -2.25, -0.23; p = 0.016). Lower levels of PTSS 3 months after admission (B = -0.13; 95% CI [-0.23, -0.03]; p = 0.015) and being employed before admission (B = 5.87; 95% CI [1.85, 9.88]; p = 0.004) were significantly associated with higher hope during the first year after admission. A small but statistically significant association was also found between higher hope and a more extended hospital stay (B = 0.08; 95% CI [0.00, 0.15]; p = 0.042).</p><p><strong>Conclusions: </strong>Hope scores remained stable during the first year after ICU admission. Lower levels of PTSS at 3 months after admission, being employed prior to admission, and having longer hospital stay were associated with higher hope during the first year after admission. Given the small sample, more research in larger samples is needed to enhance the clinical relevance of these findings.</p>","PeriodicalId":55064,"journal":{"name":"Heart & Lung","volume":"70 ","pages":"223-229"},"PeriodicalIF":2.4,"publicationDate":"2024-12-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142911156","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Methamphetamine-associated heart failure: Clinical characteristics and outcomes in a safety net population.","authors":"Anjali B Thakkar, Matthew S Durstenfeld, Yifei Ma, Sithu Win, Priscilla Y Hsue","doi":"10.1016/j.hrtlng.2024.11.012","DOIUrl":"https://doi.org/10.1016/j.hrtlng.2024.11.012","url":null,"abstract":"<p><strong>Background: </strong>Methamphetamine use is increasing and is associated with development of heart failure (HF). However, clinical characteristics and outcomes have not been well-described.</p><p><strong>Objective: </strong>To compare outcomes among individuals with HF with and without methamphetamine use in a safety-net setting.</p><p><strong>Methods: </strong>This retrospective matched cohort study included individuals with HF with history of methamphetamine use and age, gender-, and year-matched controls without history of methamphetamine use in a municipal health system from 2001 to 2019. One thousand seven hundred seventy-one individuals with methamphetamine use and HF and 3,542 age, sex, and year-of-HF-diagnosis matched controls with HF without methamphetamine use were included. The primary outcome was all-cause mortality. Secondary outcomes included time to HF hospitalization, 30-day, 90-day, and one-year HF, and all-cause readmissions.</p><p><strong>Results: </strong>The median age of the cohort was 52.1 years and 22.6 % were female. Black/African American was the most common racial identity (methamphetamine: 49.1 %; no methamphetamine: 33 %). There was no significant difference in mortality between groups (40% vs 36.6 %,HR 1.00,95 % CI 0.91,1.10,p = 1.00). A subset had an index HF hospitalization (n = 1,404, 26.4 %) during the study period, including 637 (35.9 %) with history of methamphetamine use and 767 (21.7 %) without history of methamphetamine use (relative risk 1.66,95 % CI 1.52-1.81,p < 0.0001). Among those who were ever hospitalized for HF, individuals with methamphetamine use had increased risk of HF and all-cause readmission at 30 days (RR 1.92,95 % CI 1.36-2.70,p < 0.001), 90 days (RR 1.69,95 % CI 1.35-2.12,p < 0.001), and one year (RR 1.61,95 % CI 1.36-1.91,p < 0.001).</p><p><strong>Conclusion: </strong>Despite having higher all-cause and HF readmission risk, individuals with methamphetamine-associated HF did not have higher mortality risk.</p>","PeriodicalId":55064,"journal":{"name":"Heart & Lung","volume":"70 ","pages":"214-222"},"PeriodicalIF":2.4,"publicationDate":"2024-12-28","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142904023","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Corrigendum to \"Latent profile analysis of dyspnea-related kinesiophobia in older adults with chronic obstructive pulmonary disease\" [Heart & lung: The Journal of Critical Care 69 (2024) 241247/PMID: 39522284].","authors":"Li-Chen Peng, Min Xu, Ying Wang, Run-Ling Guo, Liang Wang, Xin-Xin Wang, Li-Ling Xu","doi":"10.1016/j.hrtlng.2024.11.016","DOIUrl":"https://doi.org/10.1016/j.hrtlng.2024.11.016","url":null,"abstract":"","PeriodicalId":55064,"journal":{"name":"Heart & Lung","volume":"70 ","pages":"213"},"PeriodicalIF":2.4,"publicationDate":"2024-12-26","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142900454","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"PTX 3 (pentraxin3) is associated with lung function among people with stable-stage smoking-related chronic obstructive pulmonary disease.","authors":"Xincheng Liu, Rui Li, Maoxu Xia, Yuanyuan Gao, Jiuqi Wang, Li Pan, Zhengjin Xie, Mingming Shen, Guangcui Feng","doi":"10.1016/j.hrtlng.2024.11.010","DOIUrl":"https://doi.org/10.1016/j.hrtlng.2024.11.010","url":null,"abstract":"<p><strong>Background: </strong>Chronic obstructive pulmonary disease (COPD) is a prevalent chronic respiratory illness. Pentraxin-3 (PTX3) is abnormally elevated in the plasma of patients with acute exacerbation of COPD. However, the role and significance of PTX3 in the clinical diagnosis of COPD remain unclear.</p><p><strong>Objectives: </strong>This study was to explore the functional role of plasma PTX3 in COPD and its relationship with lung function metrics and influence on the severity of the disease.</p><p><strong>Methods: </strong>We prospectively recruited 170 patients with stable-stage COPD admitted to our hospital between June 2020 and May 2023 and healthy study participants as study participants. Based on their smoking history, all participants were classified into those with a history of smoking and those without a smoking history.</p><p><strong>Results: </strong>Stable-stage smoking-related COPD patients exhibited lower values for FEV1(% predicted) and reduced FEV1/FVC ratios, with increased values for smoking index, red cell distribution width, fibrinogen, d-dimer, white blood cell counts, neutrophil to lymphocyte ratio (NLR), Medical Research Council (mMRC) scores, COPD assessment test (CAT) score, and plasma PTX3 level. There was a positive correlation of PTX3 levels with mMRC and CAT scores and a negative correlation with FEV1 % predicted and FEV1/FVC. Increased smoking index and plasma PTX3 and NLR were independent risk factors for exacerbation in stable smoking-related COPD patients. The area under the curve (AUC) for plasma PTX3 in predicting severe COPD was 0.831.</p><p><strong>Conclusions: </strong>A plasma PTX3 level > 246.2 ng/mL could be a valuable indicator for predicting exacerbations in patients with stable-stage smoking-associated COPD exacerbation.</p>","PeriodicalId":55064,"journal":{"name":"Heart & Lung","volume":"70 ","pages":"197-203"},"PeriodicalIF":2.4,"publicationDate":"2024-12-21","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142878326","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Establishment of a prediction model for extubation failure risk in ICU patients using bedside ultrasound technology.","authors":"Jun Liu, Qianhui Yao, Pengfei Du, Dong Han, Donghui Jiang, Hongyan Qiao, Ming Huang","doi":"10.1016/j.hrtlng.2024.12.007","DOIUrl":"https://doi.org/10.1016/j.hrtlng.2024.12.007","url":null,"abstract":"<p><strong>Background: </strong>Mechanical ventilation (MV) is crucial for managing critically ill patients; however, extubation failure, associated with adverse outcomes, continues to pose a significant challenge.</p><p><strong>Objective: </strong>The purpose of this prospective observational study was to develop and validate a predictive numerical model utilizing bedside ultrasound to forecast extubation outcomes in ICU patients.</p><p><strong>Methods: </strong>We enrolled 300 patients undergoing MV, from whom clinical variables, biomarkers, and ultrasound parameters were collected. Patients were randomly assigned to two groups at a 6:4 ratio: the derivation cohort (n = 180) and the validation cohort (n = 120). A nomogram prediction model was developed using significant predictors identified through multivariate analysis and its performance was assessed and validated by evaluating its discrimination, calibration, and clinical utility.</p><p><strong>Results: </strong>A total of 300 patients (mean age 72 years; 57.3 % male) were included, with an extubation failure rate of 26.7 %. The model, including diaphragm thickening fraction (OR: 0.890, P = 0.009), modified lung ultrasound score (OR: 1.371, P < 0.001), peak relaxation velocity (OR: 1.515, P = 0.015), and APACHE II (OR: 1.181, P = 0.006), demonstrated substantial discriminative capability, as indicated by an area under the receiver operating characteristic curve (AUC) of 0.886 (95 % CI: 0.830-0.942) for the derivation cohort and 0.846 (95 % CI: 0.827-0.945) for the validation cohort. Hosmer-Lemeshow tests yielded P-values of 0.224 and 0.212 for the derivation and validation cohorts.</p><p><strong>Conclusions: </strong>We have established a risk prediction model for extubation failure in mechanically ventilated ICU patients. This risk model base on bedside ultrasound parameters provides valuable insights for identifying high-risk patients and preventing extubation failure.</p>","PeriodicalId":55064,"journal":{"name":"Heart & Lung","volume":"70 ","pages":"204-212"},"PeriodicalIF":2.4,"publicationDate":"2024-12-21","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142878119","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Visceral fat as the main tomographic risk factor for COVID-19 mortality.","authors":"Luis Ricardo Hinojosa-Gutiérrez, Adriana Lizbeth González-Sánchez, Jair Antonio Rios-Muñoz, Rodolfo Aguilar-Guerrero, Hilda Elizabeth Macías-Cervantes","doi":"10.1016/j.hrtlng.2024.12.005","DOIUrl":"https://doi.org/10.1016/j.hrtlng.2024.12.005","url":null,"abstract":"<p><strong>Background: </strong>Obesity is a risk factor for COVID-19 mortality; a BMI >35 increases the risk of death up to 12-fold; two previous studies have examined the association between visceral fat quantified by tomography and the risk of severe COVID-19, but not its association with mortality.</p><p><strong>Objective: </strong>Examine whether tomographic findings differentiated data from patients who died of COVID-19 pneumonia from those who survived in a cohort of patients at a tertiary hospital.</p><p><strong>Methods: </strong>This was a case-control study (1:1) in which we recruited data from patients at a tertiary care hospital in Mexico. Cases (N = 213) were data from patients with COVID-19 pneumonia discharged due to death, and controls (N = 216) were data from patients discharged due to improvement. All had chest computed tomography (CT) scans in the Picture Archiving and Communication System (PACS) platform. Multivariate analysis was used to identify tomographic variables associated with mortality, and odds ratios were calculated. As tomographic variables, we refer to the total severity score, the total percentage of pulmonary involvement, the pattern of involvement, the location of the lesions, and subcutaneous and visceral fat.</p><p><strong>Results: </strong>A total of 429 sets of data from Mexican patients were analyzed, with an overall age of 57 years (18-93). Sixty-three percent were male, and arterial hypertension was the most common comorbidity in 48.3 %. An odds ratio (OR) of 8.79 (95 % CI 1.44-53.73) was found for visceral fat and mortality; the rest of the tomographic variables did not show a statistically significant association.</p><p><strong>Conclusion: </strong>Visceral fat was the most significant tomographic risk factor for mortality in patients with COVID-19 pneumonia.</p>","PeriodicalId":55064,"journal":{"name":"Heart & Lung","volume":"70 ","pages":"191-196"},"PeriodicalIF":2.4,"publicationDate":"2024-12-19","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142873547","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"The impact of social frailty on mortality in older patients with chronic heart failure: A prospective cohort study.","authors":"Zongke Long, Jian Liu, Simeng Zhang, Peiyun Zhou, Bingyan Zhang, Jiurui Wang, Huimin Wei, Wenran Qu, Xiaorong Luan","doi":"10.1016/j.hrtlng.2024.12.004","DOIUrl":"https://doi.org/10.1016/j.hrtlng.2024.12.004","url":null,"abstract":"<p><strong>Background: </strong>There is still insufficient longitudinal evidence regarding the risk of mortality in older patients with chronic heart failure (CHF) and social frailty (SF).</p><p><strong>Objectives: </strong>The purpose of study was to describe the incidence rate of non-SF, pre-SF, and SF in older patients with CHF and explore its impact on mortality.</p><p><strong>Methods: </strong>The observational study was conducted at a tertiary hospital in China. According on the Help, Participation, Loneliness, Financial, Talk scale (HALFT) scores, they were divided into three groups: non-SF (0 points), pre-SF(1-2points), and SF groups(≥3points). Follow up for 6 months, observation indicator was mortality. Kaplan Meier survival analysis and the Log-rank test were used to compare the mortality of the three groups of patients. Apply the Cox proportional hazards regression model to analyze the related factors associated with mortality.</p><p><strong>Results: </strong>A total of 297 patients completed the baseline survey.The average age was 69.99±6.47, with 59.26 % men and 40.74 % women. In the 6-month follow-up, nine patients were lost to follow-up, and 35 patients died. The mortality rate of the SF group was higher than that of the non-SF group (χ²=14.805, P < 0.01). Using a multivariate Cox proportional hazards regression model, our results showed that SF, age, and marital status were risk factors for mortality.</p><p><strong>Conclusion: </strong>SF can increase the risk of mortality in older patients with CHF and is a risk factor for mortality. Healthcare providers should enhance patients' social adjustment to aid early prevention and intervention in the occurrence and development of SF to reduce the risk of mortality in older patients with CHF.</p>","PeriodicalId":55064,"journal":{"name":"Heart & Lung","volume":"70 ","pages":"177-182"},"PeriodicalIF":2.4,"publicationDate":"2024-12-19","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142873546","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Relationship between older coronary heart disease patients' phase II cardiac rehabilitation intentions, illness perceptions, and family caregivers' illness perceptions.","authors":"Yantong Xie, Xinyi Li, Min Xie, Chunxi Lin, Zhiqi Yang, Mingfang Li, Jing Chen, Meng Zhao, Zijun Guo, Jun Yan","doi":"10.1016/j.hrtlng.2024.12.006","DOIUrl":"https://doi.org/10.1016/j.hrtlng.2024.12.006","url":null,"abstract":"<p><strong>Background: </strong>Intention is an important factor in encouraging patients to receive cardiac rehabilitation. Illness perceptions of patients and individuals around them, such as family caregivers, may influence intention. However, no study has explored how family caregivers' illness perceptions enhance older coronary heart disease (CHD) patients' phase II cardiac rehabilitation intentions.</p><p><strong>Objectives: </strong>To describe older CHD patients' phase II cardiac rehabilitation intentions and their relationship with family caregivers' illness perceptions and to examine the mediating role of patients' illness perceptions.</p><p><strong>Methods: </strong>A descriptive cross-sectional study was conducted among 202 older CHD patient‒family caregiver dyads. The Chinese versions of the Revised Illness Perception Questionnaire, Willingness to Participate in Cardiac Rehabilitation Questionnaire (WPCRQ), and Cardiac Rehabilitation Inventory (CRI) were adopted. Data analysis included descriptive statistics, Pearson correlations, and structural equation modeling. Reporting followed the STROBE checklist.</p><p><strong>Results: </strong>Patients were 69.81 years and mostly male (64.85 %); family caregivers were 52.58 years and mostly female (55.94 %). Family caregivers' personal control had a direct effect on patients' phase II cardiac rehabilitation intentions (β_WPCRQ = -0.217, β_CRI = -0.228; P = 0.001). Family caregivers' personal control, treatment control, and timeline acute/chronic had indirect effects on patients' cardiac rehabilitation intentions through patients' corresponding dimensions of illness perceptions (|β|_WPCRQ = 0.086∼0.098, |β|_CRI = 0.062∼0.097; P < 0.05).</p><p><strong>Conclusion: </strong>Family caregivers' illness perceptions can affect patients' phase II cardiac rehabilitation intentions directly and indirectly through patients' illness perceptions. Interventions targeting illness perceptions in both older CHD patients and their family caregivers could be provided to improve patients' phase II cardiac rehabilitation intentions.</p>","PeriodicalId":55064,"journal":{"name":"Heart & Lung","volume":"70 ","pages":"183-190"},"PeriodicalIF":2.4,"publicationDate":"2024-12-19","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142873506","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Instruments used by physiotherapists to assess functional capacity in hospitalized patients with COVID-19: An online survey.","authors":"Ana Carolina Otoni Oliveira, Raquel Annoni, Marcia Souza Volpe, Fernando Silva Guimaraes, Camila Ferreira Leite, Flavia Marini Paro, Letícia Marcelino Sotelo Dias, Marilita Falangola Accioly","doi":"10.1016/j.hrtlng.2024.12.001","DOIUrl":"https://doi.org/10.1016/j.hrtlng.2024.12.001","url":null,"abstract":"<p><strong>Background: </strong>Assessing functional capacity in hospitalized patients with COVID-19 may have been neglected due to a great demand for resources at the height of pandemic and the lack of specific assessment instruments for this population.</p><p><strong>Objectives: </strong>To identify the instruments used to evaluate functional capacity in COVID-19 patients hospitalized in COVID-19 wards and ICUs and the associations between use of assessment instruments and physiotherapist characteristics METHODS: The survey was conducted using REDCap web-based application, following the Consensus-Based Checklist for Reporting of Survey Studies guidelines. A non-probability recruitment approach aimed at physiotherapists who had treated hospitalized patients with COVID-19 in Brazil. The instruments were classified into four domains: muscle strength, mobility, activities of daily living, and physical performance, as for the International Classification of Functioning, Disability, and Health RESULTS: Overall, 485 physiotherapists responded to the survey, 81.9% of whom used one or more instruments to assess functional capacity. The Medical Research Council (59.6%) and the Six-Minute Walk Test (21.7%) were the most commonly used instruments in COVID-19 wards; the MRC (63.9%) and the Intensive Care Mobility Scale (33.1%), in ICUs. In COVID-19 wards, higher probability of using assessment instruments was associated with being male, having training on COVID-19 management, and working > 50 h/week. In ICUs, having training on COVID-19 management and working in university hospitals were associated with higher probability of using these instruments CONCLUSIONS: Most physiotherapists used one or more instruments to assess functional capacity, assessed more than one physical domain, and used the obtained results to plan interventions.</p>","PeriodicalId":55064,"journal":{"name":"Heart & Lung","volume":"70 ","pages":"170-176"},"PeriodicalIF":2.4,"publicationDate":"2024-12-18","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142866496","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Associations between mindfulness and symptom severity among adults living with chronic obstructive pulmonary disease (COPD).","authors":"Tania T Von Visger, Kayla Wardlaw, Chin-Shang Li, Yu-Ping Chang, Lea Ann Matura","doi":"10.1016/j.hrtlng.2024.12.002","DOIUrl":"https://doi.org/10.1016/j.hrtlng.2024.12.002","url":null,"abstract":"<p><strong>Background: </strong>Mindfulness-based interventions (MBI) benefit adults with chronic obstructive pulmonary disease (COPD) by helping them manage their symptoms and improve their quality of life. Little is known about their baseline mindfulness knowledge and practice and how these may relate to symptom management.</p><p><strong>Objectives: </strong>To 1) compare symptom severity scores of depression, anxiety, dyspnea, fatigue, and insomnia between those who know and practice mindfulness and those who do not, and 2) construct phenotype profile characteristics of COPD patients based on their levels of mindfulness.</p><p><strong>Methods: </strong>339 community-dwelling adults (mean age 53.43±13.48 years, 61.28 % male, and 48.21 % White) completed an online cross-sectional survey study indicating their mindfulness knowledge, practice, level, and COPD symptom severity. After adjusting for multiple comparisons among the three groups, we used Kruskal-Wallis, Fisher's exact, and Chi-squared tests to compare variables' differences among these three mindfulness levels.</p><p><strong>Results: </strong>Participants who self-identified as knowledgeable about mindfulness (n = 315) reported significantly lower severity of dyspnea and fatigue. Participants who self-identified as current practitioners of mindfulness (n = 282) reported substantially lower symptom severity. Among the different mindfulness groups, levels of phenotype profile analysis showed statistically significant differences in demographic and clinical characteristics, including depressive symptoms, age, ethnicity, education level, and years living with COPD. We found no differences in gender or disease severity levels.</p><p><strong>Conclusions: </strong>Community-dwelling adults with COPD who practiced mindfulness reported lower symptom severity than those who did not. This suggests the potential benefits of MBI integration as a complementary health approach to symptom management. The mindfulness level phenotype profile is critical to tailoring MBIs. It can guide the design and delivery of MBIs with optimal feasibility, acceptability, effectiveness, and sustained adherence for adults with COPD according to their mindfulness level profiles.</p>","PeriodicalId":55064,"journal":{"name":"Heart & Lung","volume":"70 ","pages":"163-169"},"PeriodicalIF":2.4,"publicationDate":"2024-12-13","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142824917","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}