{"title":"Waist circumference and body surface area and the risk of developing new-onset atrial fibrillation: A systematic review and meta-analysis of observational studies","authors":"Shayan Shojaei , Hanieh Radkhah MD , Iman Akhlaghipour , Arya Nasimi Shad , Alireza Azarboo , Asma Mousavi","doi":"10.1016/j.hrtlng.2025.02.008","DOIUrl":null,"url":null,"abstract":"<div><h3>Background</h3><div>Atrial fibrillation (AF) is a prevalent cardiac arrhythmia with significant health consequences. Identifying modifiable risk factors, such as obesity, is crucial. While body mass index (BMI) is linked to increased AF risk, the association between new-onset AF (NOAF) and other anthropometric measures like waist circumference (WC) and body surface area (BSA) warrants further investigation.</div></div><div><h3>Objectives</h3><div>This systematic review and meta-analysis aimed to compare mean WC and BSA between individuals who developed NOAF and those who did not.</div></div><div><h3>Methods</h3><div>We conducted a comprehensive search up to February 2024 for studies comparing mean WC and BSA in groups with and without incident NOAF. Participants had no prior AF history. We used a random-effects model to calculate standardized mean differences (SMDs) and 95 % confidence intervals (CIs). Subgroup analyses explored NOAF occurrence following coronary artery bypass graft (CABG) surgery, in the absence of any preceding procedure, and after other cardiac procedures.</div></div><div><h3>Results</h3><div>Our analysis of 34 studies revealed that adults with NOAF had significantly higher WC (SMD = 0.20, 95 % CI 0.01; 0.39) and BSA (SMD = 0.06, 95 % CI 0.01; 0.11) compared to those without NOAF. Subgroup analysis showed a more pronounced association in individuals developing NOAF after CABG (SMD = 0.33, 95 % CI 0.17; 0.48) and in those without any prior procedure before NOAF diagnosis (SMD = 0.23, 95 % CI 0.08; 0.38) versus those without NOAF.</div></div><div><h3>Conclusion</h3><div>Higher WC and BSA appear to be significantly associated with an increased risk of NOAF, with the relations being more pronounced in specific subgroups.</div></div>","PeriodicalId":55064,"journal":{"name":"Heart & Lung","volume":"72 ","pages":"Pages 1-12"},"PeriodicalIF":2.4000,"publicationDate":"2025-03-14","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"0","resultStr":null,"platform":"Semanticscholar","paperid":null,"PeriodicalName":"Heart & Lung","FirstCategoryId":"3","ListUrlMain":"https://www.sciencedirect.com/science/article/pii/S0147956325000354","RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"Q2","JCRName":"CARDIAC & CARDIOVASCULAR SYSTEMS","Score":null,"Total":0}
引用次数: 0
摘要
背景心房颤动(房颤)是一种普遍存在的心律失常,对健康有重大影响。确定肥胖等可改变的风险因素至关重要。虽然体重指数(BMI)与房颤风险增加有关,但新发房颤(NOAF)与腰围(WC)和体表面积(BSA)等其他人体测量指标之间的关联值得进一步研究。方法我们对比较发生和未发生NOAF人群的平均WC和BSA的研究进行了全面检索,检索期截至2024年2月。参与者之前没有房颤病史。我们使用随机效应模型计算标准化平均差 (SMD) 和 95 % 置信区间 (CI)。结果我们对 34 项研究进行的分析表明,与无房颤的成人相比,有房颤的成人的 WC(SMD = 0.20,95 % CI 0.01; 0.39)和 BSA(SMD = 0.06,95 % CI 0.01; 0.11)显著更高。亚组分析显示,与无NOAF者相比,CABG术后发生NOAF者(SMD = 0.33, 95 % CI 0.17; 0.48)和NOAF诊断前未进行任何手术者(SMD = 0.23, 95 % CI 0.08; 0.38)的相关性更明显。
Waist circumference and body surface area and the risk of developing new-onset atrial fibrillation: A systematic review and meta-analysis of observational studies
Background
Atrial fibrillation (AF) is a prevalent cardiac arrhythmia with significant health consequences. Identifying modifiable risk factors, such as obesity, is crucial. While body mass index (BMI) is linked to increased AF risk, the association between new-onset AF (NOAF) and other anthropometric measures like waist circumference (WC) and body surface area (BSA) warrants further investigation.
Objectives
This systematic review and meta-analysis aimed to compare mean WC and BSA between individuals who developed NOAF and those who did not.
Methods
We conducted a comprehensive search up to February 2024 for studies comparing mean WC and BSA in groups with and without incident NOAF. Participants had no prior AF history. We used a random-effects model to calculate standardized mean differences (SMDs) and 95 % confidence intervals (CIs). Subgroup analyses explored NOAF occurrence following coronary artery bypass graft (CABG) surgery, in the absence of any preceding procedure, and after other cardiac procedures.
Results
Our analysis of 34 studies revealed that adults with NOAF had significantly higher WC (SMD = 0.20, 95 % CI 0.01; 0.39) and BSA (SMD = 0.06, 95 % CI 0.01; 0.11) compared to those without NOAF. Subgroup analysis showed a more pronounced association in individuals developing NOAF after CABG (SMD = 0.33, 95 % CI 0.17; 0.48) and in those without any prior procedure before NOAF diagnosis (SMD = 0.23, 95 % CI 0.08; 0.38) versus those without NOAF.
Conclusion
Higher WC and BSA appear to be significantly associated with an increased risk of NOAF, with the relations being more pronounced in specific subgroups.
期刊介绍:
Heart & Lung: The Journal of Cardiopulmonary and Acute Care, the official publication of The American Association of Heart Failure Nurses, presents original, peer-reviewed articles on techniques, advances, investigations, and observations related to the care of patients with acute and critical illness and patients with chronic cardiac or pulmonary disorders.
The Journal''s acute care articles focus on the care of hospitalized patients, including those in the critical and acute care settings. Because most patients who are hospitalized in acute and critical care settings have chronic conditions, we are also interested in the chronically critically ill, the care of patients with chronic cardiopulmonary disorders, their rehabilitation, and disease prevention. The Journal''s heart failure articles focus on all aspects of the care of patients with this condition. Manuscripts that are relevant to populations across the human lifespan are welcome.