European Biophysics Journal最新文献_第2页

Molecular mechanisms of mitochondrial uncoupling: focus on 2,4-dinitrophenol. 线粒体解偶联的分子机制：聚焦于2,4-二硝基苯酚。

IF 2.4 4区生物学

European Biophysics Journal Pub Date : 2026-03-16 DOI: 10.1007/s00249-026-01827-6

Elena E Pohl, Olga Jovanović

引用次数: 0

Fluorescent bionanosensor for picomolar detection of biomarkers in fluids. 用于液体中生物标志物皮摩尔检测的荧光生物纳米传感器。

IF 2.4 4区生物学

European Biophysics Journal Pub Date : 2026-03-16 DOI: 10.1007/s00249-026-01825-8

Aleksei Pashchenko, Marie Pospíšilová, Johana Šternová, Leontýna Varvařovská, Romana Široká, Hana Kalábová, Taťána Jarošíková, Šarka Beková, Sara Cruciani, Alois Nečas, Petr Novotný, Jiří Rulc, Gracian Tejral, Bruno Sopko, Margherita Maioli, Evzen Amler

引用次数: 0

Sedimentation velocity analytical ultracentrifugation (SV-AUC) for adeno-associated virus characterization: impact of cell alignment. 沉淀速度分析超离心（SV-AUC）用于腺相关病毒表征：细胞排列的影响。

IF 2.4 4区生物学

European Biophysics Journal Pub Date : 2026-03-14 DOI: 10.1007/s00249-026-01836-5

Qianyi Luo, Brandon L Doyle, Ivan L Budyak

引用次数: 0

Evidence from computational infrared spectroscopy against vibrational detection of propionate by human olfactory receptor OR51E2. 计算红外光谱对人嗅觉受体OR51E2振动检测丙酸盐的证据。

IF 2.4 4区生物学

European Biophysics Journal Pub Date : 2026-03-13 DOI: 10.1007/s00249-026-01832-9

Jacob Z Williams, Piotr E Marszalek, Weitao Yang

{"title":"Evidence from computational infrared spectroscopy against vibrational detection of propionate by human olfactory receptor OR51E2.","authors":"Jacob Z Williams, Piotr E Marszalek, Weitao Yang","doi":"10.1007/s00249-026-01832-9","DOIUrl":"https://doi.org/10.1007/s00249-026-01832-9","url":null,"abstract":"<p><p>Despite its ubiquity in nature, some details of the animal olfactory system remain unclear. One such mystery is the mechanism by which olfactory receptors (ORs) recognize the olfactant molecules they bind to. Some evidence indicates that ORs can distinguish between molecules that differ only in isotopic composition, suggesting that olfactants' vibrational modes may play a role in their recognition. In 2023, the first experimental structure of a human olfactory receptor-OR51E2-was produced, providing opportunity to shed additional light on this problem computationally. We simulate the infrared spectrum of the olfactant propionate ([Formula: see text]), as well as all its possible deuterations, in the OR51E2 binding site by quantum mechanics/molecular mechanics, with atomic positions taken at 25 time points over a 500 ns molecular dynamics simulation. The protein environment does not change the vibrational spectrum qualitatively, even at physiological temperature. The high-frequency C-H modes are about [Formula: see text] higher in energy than their deuterated counterparts, while the modes associated with the carboxyl group are almost unaffected by the C/H isotopic substitution. Because [Formula: see text] binds to OR51E2 primarily via the carboxyl end, this result means that a vibrational component to propionate detection is unlikely.</p>","PeriodicalId":548,"journal":{"name":"European Biophysics Journal","volume":" ","pages":""},"PeriodicalIF":2.4,"publicationDate":"2026-03-13","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147455154","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"生物学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Charged membrane interfaces reshape the nucleation landscape of RIPK3 amyloid variants. 带电膜界面重塑RIPK3淀粉样变异体的成核景观。

IF 2.4 4区生物学

European Biophysics Journal Pub Date : 2026-03-10 DOI: 10.1007/s00249-026-01833-8

Fátima C Escobedo-González, Andrea Gelardo, Gustavo A Titaux-Delgado, Miguel Mompeán

引用次数: 0

Biophysical insights into plasmid DNA binding by deinococcus grandis Dps nanocage. 巨球菌Dps纳米笼对质粒DNA结合的生物物理学见解。

IF 2.4 4区生物学

European Biophysics Journal Pub Date : 2026-03-06 DOI: 10.1007/s00249-026-01830-x

Ana J Carvalho, M Raquel Pacheco, João P L Guerra, Nykola C Jones, Søren V Hoffmann, Tomás Calmeiro, Elvira Fortunato, Alice S Pereira, Pedro Tavares

引用次数: 0

Magnetic field based investigation of Brugada syndrome 基于磁场的Brugada综合征研究。

IF 2.4 4区生物学

European Biophysics Journal Pub Date : 2026-03-04 DOI: 10.1007/s00249-026-01826-7

Martina Nicoletti, Anna Crispino, Alessandro Loppini, Alessio Gizzi, Letizia Chiodo, Christian Cherubini, Simonetta Filippi

{"title":"Magnetic field based investigation of Brugada syndrome","authors":"Martina Nicoletti, Anna Crispino, Alessandro Loppini, Alessio Gizzi, Letizia Chiodo, Christian Cherubini, Simonetta Filippi","doi":"10.1007/s00249-026-01826-7","DOIUrl":"10.1007/s00249-026-01826-7","url":null,"abstract":"<div>\u0000 \u0000 <p>Brugada syndrome (BrS) is an inherited cardiac disorder associated with and increased risk of sudden cardiac death. The syndrome is associated with a complex current distribution and repolarization dispersion. The traditional methods for the diagnosis rely on standard electrocardiographic (ECG) assessment of the cardiac dynamics. Recent advancements in magnetocardiography suggest that the magnetic-field based investigation of cardiac electrophysiology could offer novel perspectives for the investigation of current abnormalities in BrS patients which go beyond the conventional ECG capabilities to capture intricate current distributions. In this work, we propose a framework for the magnetic analysis of action potential disturbances in Brugada syndrome. We exploit a 1D reduced-order cable geometry for analyzing the relation between the pathological electrical activity in saddleback and coved type BrS and the corresponding magnetic field. Also, we compute transmural pseudo-magnetocardiograms and demonstrate their capabilities of detecting both types of BrS. Overall, our result highlight the potential of magnetic-field oriented investigation of cardiac disturbances related to BrS.</p>\u0000 </div>","PeriodicalId":548,"journal":{"name":"European Biophysics Journal","volume":"55 :","pages":"187 - 197"},"PeriodicalIF":2.4,"publicationDate":"2026-03-04","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://link.springer.com/content/pdf/10.1007/s00249-026-01826-7.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147353228","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"生物学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Weak protein-bicelle binding quantification via surface-based DNA nanolevers. 基于表面DNA纳米试剂的弱蛋白-单细胞结合定量研究。

IF 2.4 4区生物学

European Biophysics Journal Pub Date : 2026-03-02 DOI: 10.1007/s00249-026-01829-4

Sophie Combet, Raphael Dos Santos Morais, Audrey Comte, Angélique Cheron, Emeline Barbet-Massin, Hanna Müller-Landau, Olivier Delalande, Jean-François Hubert, Jean-Baptiste Charbonnier, Paloma Fernández Varela

引用次数: 0

Effects of synergistic/antagonistic interactions between spermidine (3+) and putrescine (2+) on gene expression through higher-order DNA structural modification. 亚精胺（3+）和腐胺（2+）协同/拮抗作用通过高阶DNA结构修饰对基因表达的影响

IF 2.4 4区生物学

European Biophysics Journal Pub Date : 2026-03-02 DOI: 10.1007/s00249-026-01831-w

Haruto Ogawa, Takashi Nishio, Yuko Yoshikawa, Takahiro Kenmotsu, Kenichi Yoshikawa

引用次数: 0

Clinical use of electrodermal activity and current developments. 皮电活动的临床应用及最新进展。

IF 2.4 4区生物学

European Biophysics Journal Pub Date : 2026-02-25 DOI: 10.1007/s00249-026-01820-z

Ali Yucel Kara, Nazan Dolu, Ferhan Esen

引用次数: 0