Nutrition Research Reviews最新文献

Sleep deprivation in development of obesity, effects on appetite regulation, energy metabolism, and dietary choices. 睡眠不足与肥胖的发展、对食欲调节、能量代谢和饮食选择的影响。

IF 5.1 2区医学

Nutrition Research Reviews Pub Date : 2025-06-01 Epub Date: 2023-10-31 DOI: 10.1017/S0954422423000264

Masoumeh Akhlaghi, Ali Kohanmoo

{"title":"Sleep deprivation in development of obesity, effects on appetite regulation, energy metabolism, and dietary choices.","authors":"Masoumeh Akhlaghi, Ali Kohanmoo","doi":"10.1017/S0954422423000264","DOIUrl":"10.1017/S0954422423000264","url":null,"abstract":"Sleep deprivation, which is a decrease in duration and quality of sleep, is a common problem in today's life. Epidemiological and interventional investigations have suggested a link between sleep deprivation and overweight/obesity. Sleep deprivation affects homeostatic and non-homoeostatic regulation of appetite, with the food reward system playing a dominant role. Factors such as sex and weight status affect this regulation; men and individuals with excess weight seem to be more sensitive to reward-driven and hedonistic regulation of food intake. Sleep deprivation may also affect weight through affecting physical activity and energy expenditure. In addition, sleep deprivation influences food selection and eating behaviours, which are mainly managed by the food reward system. Sleep-deprived individuals mostly crave for palatable energy-dense foods and have low desire for fruit and vegetables. Consumption of meals may not change but energy intake from snacks increases. The individuals have more desire for snacks with high sugar and saturated fat content. The relationship between sleep and the diet is mutual, implying that diet and eating behaviours also affect sleep duration and quality. Consuming healthy diets containing fruit and vegetables and food sources of protein and unsaturated fats and low quantities of saturated fat and sugar may be used as a diet strategy to improve sleep. Since the effects of sleep deficiency differ between animals and humans, only evidence from human subject studies has been included, controversies are discussed and the need for future investigations is highlighted.","PeriodicalId":54703,"journal":{"name":"Nutrition Research Reviews","volume":" ","pages":"4-24"},"PeriodicalIF":5.1,"publicationDate":"2025-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"71415322","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Nutritional considerations in major depressive disorder: current evidence and functional testing for clinical practice. 重度抑郁障碍的营养考虑:临床实践的现有证据和功能测试。

IF 5.1 2区医学

Nutrition Research Reviews Pub Date : 2025-06-01 Epub Date: 2023-11-15 DOI: 10.1017/S0954422423000276

Kathryn Khiroya, Eric Sekyere, Bradley McEwen, Jessica Bayes

{"title":"Nutritional considerations in major depressive disorder: current evidence and functional testing for clinical practice.","authors":"Kathryn Khiroya, Eric Sekyere, Bradley McEwen, Jessica Bayes","doi":"10.1017/S0954422423000276","DOIUrl":"10.1017/S0954422423000276","url":null,"abstract":"Depression is a multifaceted condition with diverse underlying causes. Several contributing and inter-related factors such as genetic, nutritional, neurological, physiological, gut-brain-axis, metabolic and psychological stress factors play a role in the pathophysiology of depression. This review aims to highlight the role that nutritional factors play in the aetiology of depression. Secondly, we discuss the biomedical and functional pathology tests which measure these factors, and the current evidence supporting their use. Lastly, we make recommendations on how practitioners can incorporate the latest evidence-based research findings into clinical practice. This review highlights that diet and nutrition greatly affect the pathophysiology of depression. Nutrients influence gene expression, with folate and vitamin B12 playing vital roles in methylation reactions and homocysteine regulation. Nutrients are also involved in the tryptophan/kynurenine pathway and the expression of brain-derived neurotrophic factor (BDNF). Additionally, diet influences the hypothalamic-pituitary-adrenal (HPA) response and the composition and diversity of the gut microbiome, both of which have been implicated in depression. A comprehensive dietary assessment, combined with appropriate evaluation of biochemistry and blood pathology, may help uncover contributing factors to depressive symptoms. By employing such an approach, a more targeted and personalised treatment strategy can be devised, ultimately leading to improved patient outcomes.","PeriodicalId":54703,"journal":{"name":"Nutrition Research Reviews","volume":" ","pages":"25-36"},"PeriodicalIF":5.1,"publicationDate":"2025-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"107592819","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Military rations: Nutritional, sensorial and technological quality and their effects on military physical exercise in extreme environments. 军用口粮：营养、感官和技术质量及其对极端环境下军事体育锻炼的影响。

IF 5.1 2区医学

Nutrition Research Reviews Pub Date : 2025-06-01 Epub Date: 2024-09-26 DOI: 10.1017/S0954422424000246

Vitor Andre Silva Vidal, Ida-Johanne Jensen, Øyvind Sandbakk, Pål Haugnes, Martin Winge Austeen, Rune Gjeldnes, Birger Svihus, Jørgen Lerfall

{"title":"Military rations: Nutritional, sensorial and technological quality and their effects on military physical exercise in extreme environments.","authors":"Vitor Andre Silva Vidal, Ida-Johanne Jensen, Øyvind Sandbakk, Pål Haugnes, Martin Winge Austeen, Rune Gjeldnes, Birger Svihus, Jørgen Lerfall","doi":"10.1017/S0954422424000246","DOIUrl":"10.1017/S0954422424000246","url":null,"abstract":"In recent years, many countries have significantly increased military spending, mainly due to geopolitical instability in several regions and the potential risk of armed conflicts spreading worldwide. In this context, understanding the nutritional needs of soldiers in different climates (warm, cold and high altitude) is important and directly impacts the performance and health of soldiers, especially in extreme environments. The amount of liquids, calories, and macro- and micronutrients contained in military rations must be determined considering the type of exercise, duration and environment. Military rations, in addition to being nutritionally adequate, must be practical, sustainable and easy to consume at any temperature and situation. Given these considerations, this study aimed to review scientific knowledge regarding the convenience, sensory attributes and nutritional components of military rations. Furthermore, this review studied the factors influencing soldiers' appetite, gut microbiota and nutritional needs during training or combat in extreme environments (warm, cold and high altitude). This exploration further advances our understanding of contemporary nutritional strategies for military personnel, contributing to future research and highlighting areas that must be developed.","PeriodicalId":54703,"journal":{"name":"Nutrition Research Reviews","volume":" ","pages":"324-337"},"PeriodicalIF":5.1,"publicationDate":"2025-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142332504","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

An overview of nutritional factors in the aetiopathogenesis of myocardial fibrosis in great apes. 类人猿心肌纤维化发病机制中的营养因素概述。

IF 5.1 2区医学

Nutrition Research Reviews Pub Date : 2025-06-01 Epub Date: 2024-02-12 DOI: 10.1017/S0954422424000076

Laurens Van Mulders, Laurent Locquet, Christine Kaandorp, Geert P J Janssens

{"title":"An overview of nutritional factors in the aetiopathogenesis of myocardial fibrosis in great apes.","authors":"Laurens Van Mulders, Laurent Locquet, Christine Kaandorp, Geert P J Janssens","doi":"10.1017/S0954422424000076","DOIUrl":"10.1017/S0954422424000076","url":null,"abstract":"The main cause of mortality in great apes in zoological settings is cardiovascular disease (CVD), affecting all four taxa: chimpanzee (Pan troglodytes), bonobo (Pan paniscus), gorilla (Gorilla spp.) and orangutan (Pongo spp.). Myocardial fibrosis, the most typical histological characterisation of CVD in great apes, is non-specific, making it challenging to understand the aetiopathogenesis. A multifactorial origin of disease is assumed whereby many potential causative factors are directly or indirectly related to the diet, which in wild-living great apes mainly consists of high-fibre, low-carbohydrate and very low-sodium components. Diets of great apes housed in zoological settings are often different compared with the situation in the wild. Moreover, low circulating vitamin D levels have recently been recognised in great apes housed in more northern regions. Evaluation of current supplementation guidelines shows that, despite implementation of different dietary strategies, animals stay vitamin D insufficient. Therefore, recent hypotheses designate vitamin D deficiency as a potential underlying factor in the pathogenesis of myocardial fibrosis. The aim of this literature review is to: (i) examine important differences in nutritional factors between zoological and wild great ape populations; (ii) explain the potential detrimental effects of the highlighted dietary discrepancies on cardiovascular function in great apes; and (iii) elucidate specific nutrition-related pathophysiological mechanisms that may underlie the development of myocardial fibrosis. This information may contribute to understanding the aetiopathogenesis of myocardial fibrosis in great apes and pave the way for future clinical studies and a more preventive approach to great ape CVD management.","PeriodicalId":54703,"journal":{"name":"Nutrition Research Reviews","volume":" ","pages":"37-52"},"PeriodicalIF":5.1,"publicationDate":"2025-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"139725059","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

A narrative review on dietary components and patterns and age-related macular degeneration. 关于膳食成分和模式与老年性黄斑变性的叙述性综述。

IF 5.1 2区医学

Nutrition Research Reviews Pub Date : 2025-06-01 Epub Date: 2024-01-15 DOI: 10.1017/S0954422424000015

Emine Koçyiğit, Nazlıcan Erdoğan Gövez, Sabriye Arslan, Duygu Ağagündüz

{"title":"A narrative review on dietary components and patterns and age-related macular degeneration.","authors":"Emine Koçyiğit, Nazlıcan Erdoğan Gövez, Sabriye Arslan, Duygu Ağagündüz","doi":"10.1017/S0954422424000015","DOIUrl":"10.1017/S0954422424000015","url":null,"abstract":"Age-related macular degeneration (AMD) is one of the most prevalent eye diseases among the ageing population worldwide. It is a leading cause of blindness in individuals over 55, particularly in industrialised Western countries. The prevalence of AMD increases with age, and genetic factors and environmental influences are believed to contribute to its development. Among the environmental factors, diet plays a significant role in AMD. This review explores the association between dietary components, dietary patterns and AMD. Various nutrients, non-nutrient substances and dietary models that have the potential to counteract oxidative stress and inflammation, which are underlying mechanisms of AMD, are discussed. Consuming fruits, vegetables, fish and seafood, whole grains, olive oil, nuts and low-glycaemic-index foods has been highlighted as beneficial for reducing the risk of AMD. Adhering to the Mediterranean diet, which encompasses these elements, can be recommended as a dietary pattern for AMD. Furthermore, the modulation of the gut microbiota through dietary interventions and probiotics has shown promise in managing AMD.","PeriodicalId":54703,"journal":{"name":"Nutrition Research Reviews","volume":" ","pages":"143-170"},"PeriodicalIF":5.1,"publicationDate":"2025-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"139467170","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Selenium supplementation in chronic kidney disease patients undergoing haemodialysis: a systematic review of the effects on plasma selenium, antioxidant and inflammatory markers, immunological parameters and thyroid hormones. 接受血液透析的慢性肾病患者补硒：对血浆硒、抗氧化和炎症标志物、免疫学参数和甲状腺激素影响的系统综述。

IF 5.1 2区医学

Nutrition Research Reviews Pub Date : 2025-06-01 Epub Date: 2024-09-25 DOI: 10.1017/S0954422424000222

Pricilla de C Trigueira, Viviane de O Leal, Barbara R Cardoso, Denise Mafra, Marina C Araujo, Milena B Stockler-Pinto

{"title":"Selenium supplementation in chronic kidney disease patients undergoing haemodialysis: a systematic review of the effects on plasma selenium, antioxidant and inflammatory markers, immunological parameters and thyroid hormones.","authors":"Pricilla de C Trigueira, Viviane de O Leal, Barbara R Cardoso, Denise Mafra, Marina C Araujo, Milena B Stockler-Pinto","doi":"10.1017/S0954422424000222","DOIUrl":"10.1017/S0954422424000222","url":null,"abstract":"Selenium (Se) is a mineral with several biological functions, and studies have shown that its deficiency can be linked to many complications in patients with chronic kidney disease (CKD). This study aims to systematically review the effects of Se supplementation in patients with CKD undergoing haemodialysis (HD). This systematic review was carried out according to the PRISMA statement. Clinical trials were searched in PubMed, Lilacs, Embase, Scopus and Cochrane Library databases from inception to July 2021 and updated in July 2024. The protocol was registered on PROSPERO (CRD42021231444). Two independent reviewers performed the study screening and data extraction, and the risk of bias was evaluated using the Cochrane Collaboration tool. Thirteen studies were included in this review. Only nine studies showed results on Se levels; in all, reduced Se levels were observed before supplementation. A positive effect of supplementation on plasma Se level was demonstrated. Of the ten studies analysed, six demonstrated positive effects on antioxidant and inflammatory markers. Only one study analysed immunological parameters, showing a positive impact. From two studies that analysed thyroid hormones, only one showed positive results. All studies were classified as high risk of bias. The findings suggest that Se supplementation significantly increases plasma Se levels in these patients; however, there are still not enough studies to clarify the effects of Se supplementation on the antioxidant and inflammatory markers, immune system and thyroid hormones. Further studies are needed to elucidate the effects of Se supplementation and to provide a recommendation for patients with CKD undergoing HD.","PeriodicalId":54703,"journal":{"name":"Nutrition Research Reviews","volume":" ","pages":"294-305"},"PeriodicalIF":5.1,"publicationDate":"2025-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142332506","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Mollusc and crustacean consumption in the first 1000 days: a scoping review. 头 1,000 天的软体动物和甲壳类动物消费：范围审查。

IF 5.1 2区医学

Nutrition Research Reviews Pub Date : 2025-06-01 Epub Date: 2024-02-12 DOI: 10.1017/S0954422424000064

Brietta M Oaks, Emmanuel A Gyimah, Eliza Kleban, Kathleen Ragsdale, Lora L Iannotti

{"title":"Mollusc and crustacean consumption in the first 1000 days: a scoping review.","authors":"Brietta M Oaks, Emmanuel A Gyimah, Eliza Kleban, Kathleen Ragsdale, Lora L Iannotti","doi":"10.1017/S0954422424000064","DOIUrl":"10.1017/S0954422424000064","url":null,"abstract":"Mollusc and crustacean consumption in the first 1000 d may improve maternal and child health by providing essential nutrients. However, in some contexts, molluscs and crustaceans have been associated with allergies and environmental contamination, potentially leading to adverse health and development outcomes. It is unclear whether the health benefits of consuming molluscs and crustaceans, collectively classified as shellfish in nutrition, are outweighed by the potential risks to pregnant women and children. We conducted a scoping review (PROSPERO: CRD42022320454) in PubMed, Scopus and EBSCO Global Health of articles published between January 2000 and March 2022 that assessed shellfish consumption during pregnancy, lactation or childhood (0-2 years) in relation to maternal health, child health or child development. A total of forty-six articles were included in this review. Overall, shellfish consumption was associated with higher biomarkers of environmental contaminants, with mercury being the most studied and having the strongest evidence base. The limited research on nutritional biomarker status shows an association between shellfish consumption and iodine status. Preterm birth was not associated with shellfish consumption, but newborn anthropometry showed mixed results, with several studies reporting lower birth weight with higher shellfish consumption. The few studies that examined child development and maternal health outcomes reported no significant associations. This review revealed trade-off health risks and benefits with inclusion of molluscs and crustaceans in the dietary patterns of mothers and young children. More research is needed to understand how these aquatic animal-source foods may be safely consumed and leveraged for improving human nutrition.","PeriodicalId":54703,"journal":{"name":"Nutrition Research Reviews","volume":" ","pages":"181-191"},"PeriodicalIF":5.1,"publicationDate":"2025-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"139725015","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Nutrition and health effects of pectin: A systematic scoping review of human intervention studies. 果胶对营养和健康的影响：人类干预研究的系统性范围界定审查。

IF 5.1 2区医学

Nutrition Research Reviews Pub Date : 2025-06-01 Epub Date: 2024-09-26 DOI: 10.1017/S0954422424000180

Annika M Weber, Nélida Pascale, Fangjie Gu, Elizabeth P Ryan, Frederique Respondek

{"title":"Nutrition and health effects of pectin: A systematic scoping review of human intervention studies.","authors":"Annika M Weber, Nélida Pascale, Fangjie Gu, Elizabeth P Ryan, Frederique Respondek","doi":"10.1017/S0954422424000180","DOIUrl":"10.1017/S0954422424000180","url":null,"abstract":"Pectin is composed of a group of complex polysaccharides that are naturally found in various plants and are associated with a range of beneficial health effects. Health outcomes from dietary pectin can vary depending on botanical origin, dietary dose and structure of pectin. The objective of this scoping review is to build a comprehensive overview of the current evidence available on intervention studies conducted in humans and to better understand the possible knowledge gaps in terms of structure-function relationships across the different health-related effects. PubMed and Embase databases were searched using PRISMA-ScR guidelines, yielding 141 references (from the initial 3704), representing 134 intervention studies performed between 1961 and 2022 that met inclusion criteria. Studies were divided into six categories, which included gut health, glycaemic response and appetite, fat metabolism, bioavailability of micronutrients, immune response and other topics. Review of these human intervention studies identified a variety of cohort characteristics and populations (life stage, health status, country), sources/types of pectin (i.e. citrus, sugarbeet, apple, other and non-defined), intervention timeframes (from one single intake to 168 d) and doses (0.1-50 g/d) that were tested for health outcomes in people. Gut health, post-prandial glucose regulation and maintenance of blood cholesterol represented the largest categories of studied outcomes. Further research to strengthen the structure-function relationships for pectin with health properties and associated outcomes is warranted and will benefit from a more precise description of physico-chemical characteristics and molecular compositions, such as degree of esterification, weight, degree of branching, viscosity, gel formation and solubility.","PeriodicalId":54703,"journal":{"name":"Nutrition Research Reviews","volume":" ","pages":"306-323"},"PeriodicalIF":5.1,"publicationDate":"2025-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142332505","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Effects of energy-restricted diets with or without nuts on weight, body composition and glycaemic control in adults: a scoping review. 含或不含坚果的能量限制饮食对成人体重、身体成分和血糖控制的影响：范围综述。

IF 5.1 2区医学

Nutrition Research Reviews Pub Date : 2025-06-01 Epub Date: 2024-02-23 DOI: 10.1017/S0954422424000106

Lauren C Mead, Alison M Hill, Sharayah Carter, Alison M Coates

{"title":"Effects of energy-restricted diets with or without nuts on weight, body composition and glycaemic control in adults: a scoping review.","authors":"Lauren C Mead, Alison M Hill, Sharayah Carter, Alison M Coates","doi":"10.1017/S0954422424000106","DOIUrl":"10.1017/S0954422424000106","url":null,"abstract":"Energy-restricted (ER) diets promote weight loss and improve body composition and glycaemic control. Nut consumption also improves these parameters. However, less is known about the combined benefit of these two strategies. This scoping review implemented a systematic search of Medline, Embase and Scopus to identify randomised controlled trials evaluating the effect of ER diets with or without nuts on body mass, body composition and glycaemic control in adults. After reviewing titles and abstracts, twenty-nine full-text articles were screened, resulting in seven studies reported in eight papers that met the inclusion criteria. Energy restriction was achieved by prescribing a set energy target or reducing intake by 1000-4200 kJ from daily energy requirements. Interventions ranged from 4 to 52 weeks in duration and contained 42-84 g/d of almonds, peanuts, pistachios or walnuts. While all studies reported that energy restriction resulted in significant weight loss, the addition of nuts to ER diets demonstrated significantly greater weight loss in only approximately half of the included studies (4/7 studies). There was limited evidence to support additional benefits from nuts for body composition measures or glycaemic control. Although improvements in weight loss and glycaemia were not consistent when nuts were included in ER diets, no study revealed an adverse effect of nut consumption on health outcomes. Future studies could explore the effect of consuming different types and amounts of nuts, combined with various levels of energy restriction on weight, body composition and glycaemic control.","PeriodicalId":54703,"journal":{"name":"Nutrition Research Reviews","volume":" ","pages":"202-218"},"PeriodicalIF":5.1,"publicationDate":"2025-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"139934271","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Emerging evidence on selenoneine and its public health relevance in coastal populations: a review and case study of dietary Se among Inuit populations in the Canadian Arctic. 有关硒酮及其在沿海居民中的公共卫生意义的新证据：加拿大北极地区因纽特人膳食中硒含量的回顾与案例研究。

IF 5.1 2区医学

Nutrition Research Reviews Pub Date : 2025-06-01 Epub Date: 2024-02-08 DOI: 10.1017/S0954422424000039

Matthew Little, Adel Achouba, Pierre Ayotte, Mélanie Lemire

{"title":"Emerging evidence on selenoneine and its public health relevance in coastal populations: a review and case study of dietary Se among Inuit populations in the Canadian Arctic.","authors":"Matthew Little, Adel Achouba, Pierre Ayotte, Mélanie Lemire","doi":"10.1017/S0954422424000039","DOIUrl":"10.1017/S0954422424000039","url":null,"abstract":"Selenium is an essential mineral yet both deficiency and excess are associated with adverse health effects. Dietary intake of Se in humans varies greatly between populations due to food availability, dietary preferences, and local geological and ecosystem processes impacting Se accumulation into agricultural products and animal populations. We argue there is a need to evaluate and reconsider the relevance of public health recommendations on Se given recent evidence, including the metabolic pathways and health implications of Se. This argument is particularly pertinent for Inuit populations in Northern Canada, who often exceed dietary tolerable upper intake levels and exhibit very high whole blood Se concentrations due to their dependence on local country foods high in the newly discovered Se compound, selenoneine. Since selenoneine appears to have lower toxicity compared to other Se species and does not contribute to the circulating pools of Se for selenoprotein synthesis, we argue that total dietary Se or total Se in plasma or whole blood are poor indicators of Se adequacy for human health in these populations. Overall, this review provides an overview of the current evidence of Se speciation, deficiency, adequacy, and excess and implications for human health and dietary recommendations, with particular reference to Inuit populations in the Canadian Arctic and other coastal populations consuming marine foods.","PeriodicalId":54703,"journal":{"name":"Nutrition Research Reviews","volume":" ","pages":"171-180"},"PeriodicalIF":5.1,"publicationDate":"2025-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"139704088","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0