Nutrition Research Reviews最新文献_第10页

Dietary protein requirements and recommendations for healthy older adults: a critical narrative review of the scientific evidence - CORRIGENDUM. 健康老年人的膳食蛋白质需求量和建议：科学证据的批判性叙述回顾 - CORRIGENDUM。

IF 5.1 2区医学

Nutrition Research Reviews Pub Date : 2023-06-01 Epub Date: 2021-12-17 DOI: 10.1017/S0954422421000408

Yusuke Nishimura, Grith Højfeldt, Leigh Breen, Inge Tetens, Lars Holm

引用次数: 0

NAFLD and vitamin D: Evidence for intersection of microRNA-regulated pathways. NAFLD和维生素D: microrna调控通路交叉的证据。

IF 5.7 2区医学

Nutrition Research Reviews Pub Date : 2023-06-01 DOI: 10.1017/S095442242100038X

Zixuan Zhang, Rachel Moon, James L Thorne, J Bernadette Moore

{"title":"NAFLD and vitamin D: Evidence for intersection of microRNA-regulated pathways.","authors":"Zixuan Zhang, Rachel Moon, James L Thorne, J Bernadette Moore","doi":"10.1017/S095442242100038X","DOIUrl":"https://doi.org/10.1017/S095442242100038X","url":null,"abstract":"Non-alcoholic fatty liver disease (NAFLD) is now the most common cause of chronic liver disease, worldwide. The molecular pathogenesis of NAFLD is complex, involving numerous signalling molecules, including microRNAs (miRNAs). Dysregulation of miRNA expression is associated with hepatic inflammation, fibrosis and hepatocellular carcinoma. Although miRNAs are also critical to the cellular response to vitamin D, mediating regulation of the vitamin D receptor and vitamin D's anti-cancer effects, the role of vitamin-D-regulated miRNAs in NAFLD pathogenesis has been relatively unexplored. Therefore, this review aims to critically assess the evidence for a potential subset of miRNAs that are both dysregulated in NAFLD and modulated by vitamin D. Comprehensive review of eighty-nine human studies identified twenty-five miRNAs found dysregulated in more than one NAFLD study. In contrast, only seventeen studies, including a protocol for a trial in NAFLD, had examined miRNAs in relation to vitamin D status, response to supplementation, or vitamin D in the context of the liver. This paper summarises these data and reviews the biological roles of six miRNAs (miR-21, miR-30, miR-34, miR-122, miR-146, miR-200) found dysregulated in multiple independent NAFLD studies. While modulation of miRNAs by vitamin D has been understudied, integration of the data suggests seven vitamin-D-modulated miRNAs (miR-27, miR-125, miR-155, miR-192, miR-223, miR-375, miR-378) potentially relevant to NAFLD pathogenesis. Our summary tables provide a significant resource to underpin future hypothesis-driven research, and we conclude that the measurement of serum and hepatic miRNAs in response to vitamin D supplementation in larger trials is warranted.","PeriodicalId":54703,"journal":{"name":"Nutrition Research Reviews","volume":"36 1","pages":"120-139"},"PeriodicalIF":5.7,"publicationDate":"2023-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"9449402","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 9

Functional properties of edible insects: a systematic review. 食用昆虫的功能特性:系统综述。

IF 5.7 2区医学

Nutrition Research Reviews Pub Date : 2023-06-01 DOI: 10.1017/S0954422421000366

V D'Antonio, N Battista, G Sacchetti, C Di Mattia, M Serafini

{"title":"Functional properties of edible insects: a systematic review.","authors":"V D'Antonio, N Battista, G Sacchetti, C Di Mattia, M Serafini","doi":"10.1017/S0954422421000366","DOIUrl":"https://doi.org/10.1017/S0954422421000366","url":null,"abstract":"Consumption of edible insects has been widely suggested as an environmentally sustainable substitute for meat to reduce greenhouse gas emissions. However, the novel research field for edible insects relies on the content of bioactive ingredients and on the ability to induce a functional effect in humans. The goal of this manuscript is to review the available body of evidence on the properties of edible insects in modulating oxidative and inflammatory stress, platelet aggregation, lipid and glucose metabolism and weight control. A search for literature investigating the functional role of edible insects was carried out in the PubMed database using specific keywords. A total of 55 studies, meeting inclusion criteria after screening, were divided on the basis of the experimental approach: in vitro studies, cellular models/ex vivo studies or in vivo studies. In the majority of the studies, insects demonstrated the ability to reduce oxidative stress, modulate antioxidant status, restore the impaired activity of antioxidant enzymes and reduce markers of oxidative damage. Edible insects displayed anti-inflammatory activity reducing cytokines and modulating specific transcription factors. Results from animal studies suggest that edible insects can modulate lipid and glucose metabolism. The limited number of studies focused on the assessment of anti-coagulation activity of edible insects makes it difficult to draw conclusions. More evidence from dietary intervention studies in humans is needed to support the promising evidence from in vitro and animal models about the functional role of edible insect consumption.","PeriodicalId":54703,"journal":{"name":"Nutrition Research Reviews","volume":"36 1","pages":"98-119"},"PeriodicalIF":5.7,"publicationDate":"2023-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"9453020","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 10

Efficacy of resveratrol in male urogenital tract dysfunctions: an evaluation of pre-clinical data. 白藜芦醇治疗男性泌尿生殖道功能障碍的疗效:临床前数据的评估。

IF 5.7 2区医学

Nutrition Research Reviews Pub Date : 2023-06-01 DOI: 10.1017/S0954422421000354

F B Calmasini, F H Silva, E C Alexandre, E Antunes

{"title":"Efficacy of resveratrol in male urogenital tract dysfunctions: an evaluation of pre-clinical data.","authors":"F B Calmasini, F H Silva, E C Alexandre, E Antunes","doi":"10.1017/S0954422421000354","DOIUrl":"https://doi.org/10.1017/S0954422421000354","url":null,"abstract":"Resveratrol is a polyphenol found naturally in fruits and plants. Recently, studies in humans and animal models have suggested beneficial properties of this polyphenol, such as improvements to metabolic and lipid profiles, along with antioxidant, anti-inflammatory and anti-proliferative effects. In the urogenital tract (UGT), resveratrol has also been tested clinically and experimentally as a therapeutic drug in several diseases; however, the translational efficacy of resveratrol, especially in UGT, is still a matter of debate. In the present review, we address the pre-clinical efficacy of resveratrol in UGT-related dysfunctions, focusing on lower urinary tract symptoms, non-cancerous prostatic disease (benign prostatic hyperplasia and prostatitis) and erectile dysfunction. In vitro studies indicate that resveratrol reduces inflammatory markers and oxidative stress, and improves endothelial function in UGT organs and cells isolated from humans and animals. Despite displaying low oral bioavailability, in vivo administration of resveratrol largely improves erectile dysfunction, benign prostatic hyperplasia, prostatitis and voiding impairments, as evidenced in different animal models. Resveratrol also acts as a microbiota modulator, which may explain some of its beneficial effects in vivo. In contrast to the large amount of pre-clinical data, there are insufficient clinical trials to establish resveratrol treatment efficacy in human UGT-related diseases. In summary, we provide an overview of the in vivo and in vitro efficacy of resveratrol in animal and human UGT dysfunctions, which may support future clinical trials.","PeriodicalId":54703,"journal":{"name":"Nutrition Research Reviews","volume":"36 1","pages":"86-97"},"PeriodicalIF":5.7,"publicationDate":"2023-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"9449398","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 1

A scoping review of chronotype and temporal patterns of eating of adults: Tools used, findings, and future directions - CORRIGENDUM. 成人饮食的时间类型和时间模式的范围综述：使用的工具，发现和未来的方向-勘误表。

IF 5.1 2区医学

Nutrition Research Reviews Pub Date : 2023-06-01 Epub Date: 2022-03-14 DOI: 10.1017/S095442242200004X

Yan Yin Phoi, Michelle Rogers, Maxine P Bonham, Jillian Dorrian, Alison M Coates

引用次数: 0

Vitamin D and acute and severe illness - a mechanistic and pharmacokinetic perspective. 维生素D与急性和严重疾病-机制和药代动力学的观点。

IF 5.7 2区医学

Nutrition Research Reviews Pub Date : 2023-06-01 DOI: 10.1017/S0954422421000251

Inez Schoenmakers, William D Fraser, Alastair Forbes

{"title":"Vitamin D and acute and severe illness - a mechanistic and pharmacokinetic perspective.","authors":"Inez Schoenmakers, William D Fraser, Alastair Forbes","doi":"10.1017/S0954422421000251","DOIUrl":"https://doi.org/10.1017/S0954422421000251","url":null,"abstract":"The coronavirus disease 2019 (COVID-19) pandemic has generated high interest in factors modulating risk of infection, disease severity and recovery. Vitamin D has garnered interest since it is known to modulate immune function and vitamin D deficiency is associated with increased risk of respiratory infections and adverse health outcomes in severely ill patients. There are no population representative data on the direct relationship between vitamin D status and severe acute respiratory syndrome coronavirus 2 infection risk and severity of COVID-19. Data from intervention studies are limited to four studies. Here we summarise findings regarding vitamin D status and metabolism and their alterations during severe illness, relevant to COVID-19 patients. Further, we summarise vitamin D intervention studies with respiratory disease outcomes and in critically ill patients and provide an overview of relevant patient and population guidelines. Vitamin D deficiency is highly prevalent in hospitalised patients, particularly when critically ill, including those with COVID-19. Acute and critical illness leads to pronounced changes in vitamin D metabolism and status, suggestive of increased requirements. This needs to be considered in the interpretation of potential links between vitamin D status and disease risk and severity and for patient management. There is some evidence that vitamin D supplementation decreases the risk of respiratory tract infections, while supplementation of intensive care unit patients has shown little effect on disease severity or length of treatment. Considering the high prevalence of deficiency and low risks associated with supplementation, pro-actively applying current population and patient management guidelines to prevent, monitor and correct vitamin D deficiency is appropriate.","PeriodicalId":54703,"journal":{"name":"Nutrition Research Reviews","volume":"36 1","pages":"23-38"},"PeriodicalIF":5.7,"publicationDate":"2023-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"9453012","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 3

Epigenetic linkage of systemic lupus erythematosus and nutrition. 系统性红斑狼疮与营养的表观遗传连锁。

IF 5.7 2区医学

Nutrition Research Reviews Pub Date : 2023-06-01 DOI: 10.1017/S0954422421000287

Tatiana Montoya, María Luisa Castejón, Rocío Muñoz-García, Catalina Alarcón-de-la-Lastra

{"title":"Epigenetic linkage of systemic lupus erythematosus and nutrition.","authors":"Tatiana Montoya, María Luisa Castejón, Rocío Muñoz-García, Catalina Alarcón-de-la-Lastra","doi":"10.1017/S0954422421000287","DOIUrl":"https://doi.org/10.1017/S0954422421000287","url":null,"abstract":"The term 'epigenetics' refers to a series of meiotically/mitotically inheritable alterations in gene expression, related to environmental factors, without disruption on DNA sequences of bases. Recently, the pathophysiology of autoimmune diseases (ADs) has been closely linked to epigenetic modifications. In fact, epigenetic mechanisms can modulate gene expression or repression of targeted cells and tissues involved in autoimmune/inflammatory conditions acting as keys effectors in regulation of adaptive and innate responses. ADs, as systemic lupus erythematosus (SLE), a rare disease that still lacks effective treatment, is characterised by epigenetic marks in affected cells. Taking into account that epigenetic mechanisms have been proposed as a winning strategy in the search of new, more specific and personalised therapeutics agents, pharmacology and pharmaco-epigenetic studies about epigenetic regulations of ADs may provide novel individualised therapies. Focusing on possible implicated factors on development and predisposition of SLE, diet is feasibly one of the most important factors since it is linked directly to epigenetic alterations and these epigenetic changes may augment or diminish the risk of SLE. Nevertheless, several studies have suggested that dietary therapy could be promising to SLE patients via prophylactic actions deprived of side effects of pharmacology, decreasing co-morbidities and improving lifestyle of SLE sufferers. Herein, we review and discuss the cross-link between epigenetic mechanisms on SLE predisposition and development, as well as the influence of dietary factors on regulation of epigenetic modifications that may eventually make a positive impact on SLE patients.","PeriodicalId":54703,"journal":{"name":"Nutrition Research Reviews","volume":"36 1","pages":"39-59"},"PeriodicalIF":5.7,"publicationDate":"2023-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"9447652","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 8

Current perspectives on global sugar consumption: definitions, recommendations, population intakes, challenges and future direction - CORRIGENDUM. 全球食糖消费现状：定义、建议、人口摄入量、挑战和未来方向 - CORRIGENDUM。

IF 5.1 2区医学

Nutrition Research Reviews Pub Date : 2023-06-01 Epub Date: 2023-03-16 DOI: 10.1017/S0954422422000075

Janette Walton, Haley Bell, Roberta Re, Anne P Nugent

引用次数: 0

Olive oil and wine as source of multi-target agents in the prevention of Alzheimer disease. 橄榄油和葡萄酒作为多靶点药物的来源预防阿尔茨海默病。

IF 5.7 2区医学

Nutrition Research Reviews Pub Date : 2023-06-01 DOI: 10.1017/S095442242100041X

Paula Silva, María Rodríguez-Pérez, Óscar Gómez-Torres, Emma Burgos-Ramos

{"title":"Olive oil and wine as source of multi-target agents in the prevention of Alzheimer disease.","authors":"Paula Silva, María Rodríguez-Pérez, Óscar Gómez-Torres, Emma Burgos-Ramos","doi":"10.1017/S095442242100041X","DOIUrl":"https://doi.org/10.1017/S095442242100041X","url":null,"abstract":"Olive oil and wine are consumed daily worldwide, and they constitute the fundamental pillars of the healthy Mediterranean diet. Polyphenolic compounds, naturally present in both olive oil and wine, are responsible for their beneficial properties. Current studies have shown the neuroprotective effects of polyphenols independently of their well-known antioxidant action. In this work, we have focused on reviewing the protective effect of polyphenols from extra virgin olive oil and wine in Alzheimer´s disease (AD), to emphasise that both foods could be a possible therapeutic tool. Beneficial effects have been described in β-aggregation, neurofibrillary tangles, autophagy and mitochondrial function, as well as in cerebral insulin resistance. Furthermore, to date, a harmful dose has not been described. Both pre-clinical and clinical works demonstrate that polyphenols act on neuropathological and cognitive disorders of AD, preventing or stopping the onset of this devastating disease. However, there are certain limitations in these studies, since it is very difficult to research diseases that lead to cognitive impairment. Although all the findings obtained are very encouraging, more studies should be carried out investigating the use of the polyphenols from olive oil and wine as therapeutic agents in the progression of AD. Therefore, more longitudinal studies in humans with a homogeneous cohort of patients are necessary to corroborate the efficacy of these nutraceuticals, as well as determine the most appropriate dose for this purpose.","PeriodicalId":54703,"journal":{"name":"Nutrition Research Reviews","volume":"36 1","pages":"140-154"},"PeriodicalIF":5.7,"publicationDate":"2023-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"9447665","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 6

NRR volume 36 issue 1 Front matter NRR第36卷第1期封面

IF 5.7 2区医学

Nutrition Research Reviews Pub Date : 2023-05-10 DOI: 10.1017/s0954422423000057

引用次数: 0