Environmental Sciences Europe最新文献

{"title":"Recommendations for regulatory coherence and effective management of persistent and mobile substances in the soil-sediment–water system to move the circular economy forward","authors":"Julia Hartmann,&nbsp;Kaitlyn Carter,&nbsp;Millaray Sierra-Olea,&nbsp;Adriana E. Sardi,&nbsp;Peter A. Behnisch,&nbsp;Steffen Kittlaus,&nbsp;Matthias Zessner,&nbsp;Carme Bosch,&nbsp;Veronika Zhiteneva,&nbsp;Amélie Cavelan,&nbsp;Sandrine Andres,&nbsp;Valeria Dulio,&nbsp;Pierre Boucard,&nbsp;Julie Lions,&nbsp;Petra A. M. Hogervorst","doi":"10.1186/s12302-026-01448-y","DOIUrl":"10.1186/s12302-026-01448-y","url":null,"abstract":"<div><p>Persistent, mobile, and toxic (PMT) or very persistent and very mobile (vPvM) substances, such as many per- and polyfluoroalkyl substances (PFAS), pose a significant environmental and regulatory challenge due to their persistence in water, soil, and sediment. These substances bypass conventional treatment methods, endangering human and environmental health and impeding the European Union’s (EU) sustainability agenda, including the Green Deal, the Circular Economy Action Plan (CEAP), the Zero Pollution Action Plan (ZPAP), the Chemicals Strategy for Sustainability (CSS), and the EU Soil Strategy. The recent inclusion of PMT and vPvM hazard classes in the Classification Labeling and Packaging (CLP) regulation 1272/2008, via Delegated Regulation (EU) 2023/707 marks an important step in recognizing these properties. However, the current regulatory landscape for PMT/vPvM substances remains fragmented and complex, with different environmental compartments—soil, sediment, water, and sludge—addressed under separate downstream policies and with the translation of these criteria into coherent measures across environmental legislation still pending. Policy updates, as well as improvements, and additions to current regulations are urgently needed to ensure harmonized management of PMT/vPvM substances across the soil-sediment–water system and to achieve the EU’s circular economy and zero pollution ambitions. To this end, the Horizon 2020 project PROMISCES proposes eight policy recommendations across four policy fields: substance regulations, circular resource management, technology performance and pollution control, and tools and data management. These recommendations integrate PROMISCES research findings, stakeholder input, and regulatory analysis to support the EU circularity and zero pollution ambitions.</p></div>","PeriodicalId":546,"journal":{"name":"Environmental Sciences Europe","volume":"38 1","pages":""},"PeriodicalIF":7.1,"publicationDate":"2026-06-25","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://link.springer.com/content/pdf/10.1186/s12302-026-01448-y.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148927976","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"环境科学与生态学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Integrated assessment of biostimulants with water and fertilizer saving techniques: implications for environmental contamination and health hazard in tomato crops across Europe","authors":"C. Pignata,&nbsp;Si. Bonetta,&nbsp;S. Filippetti,&nbsp;E. Gasparro,&nbsp;V. Porro,&nbsp;E. Fea,&nbsp;G. Gilli,&nbsp;L. Celi,&nbsp;E. Carraro","doi":"10.1186/s12302-026-01446-0","DOIUrl":"10.1186/s12302-026-01446-0","url":null,"abstract":"<div><h3>Background</h3><p>Tomato (<i>Solanum lycopersicum</i> L.) production faces increasing challenges related to water scarcity, intensive input use, and environmental contamination. In this context, biostimulants combined with water- and fertilizer-saving strategies have been proposed to enhance crop performance while reducing environmental impacts. However, their integrated effects on soil contamination and potential health hazards remain insufficiently understood. This study, conducted within the Horizon 2020 TOMRES project, provides a multidisciplinary evaluation of these aspects across different European agroecosystems.</p><h3>Results</h3><p>Results showed that pseudo-total potentially toxic elements (PTE) concentrations varied among sites, occasionally exceeding reference thresholds. However, bioaccessible PTEs generally remained low and below toxicity levels. Biostimulant application and reduced water and nutrient inputs had limited effects on PTE bioaccessibility, although localized increases were observed in soils with higher baseline contamination. Microbiological analyses revealed high variability across sites, with total plate counts (TPCs) influenced more by environmental conditions than by agronomic treatments. Faecal indicators were generally low, and <i>Salmonella</i> spp. was detected only by molecular methods, without clear association with other microbial parameters. Ecotoxicological assays indicated low to moderate toxicity overall, with algae showing the highest sensitivity; biostimulants occasionally mitigated toxic effects, particularly under well-watered conditions. Multivariate analysis confirmed that site-specific factors, including soil properties and baseline conditions, were the primary determinants of chemical, microbiological, and ecotoxicological variability, exceeding the influence of agronomic treatments.</p><h3>Conclusions</h3><p>Despite some methodological limitations inherent in this multidisciplinary study, the results suggest that the integration of biostimulants with water- and fertilizer-saving practices did not result in significant environmental or health hazards under the studied conditions. However, the outcomes highlight the importance of site-specific assessments, particularly in soils with elevated contaminant levels. These findings support the potential of sustainable agronomic strategies in tomato production while emphasizing the need for context-dependent management and further research on long-term impacts and food safety implications. Future research on this topic should be expanded by developing integrated risk assessment frameworks that combine chemical, microbiological, and ecotoxicological factors to support sustainable agriculture and protect public health.</p><h3>Graphical Abstract</h3>\u0000<div><figure><div><div><picture><source><img></source></picture></div></div></figure></div></div>","PeriodicalId":546,"journal":{"name":"Environmental Sciences Europe","volume":"38 1","pages":""},"PeriodicalIF":7.1,"publicationDate":"2026-06-25","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://link.springer.com/content/pdf/10.1186/s12302-026-01446-0.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148927975","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"环境科学与生态学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Export diversification meets environmental innovation: pathways to sustainability","authors":"Elma Satrovic,&nbsp;Ojonugwa Usman,&nbsp;Andrew Adewale Alola,&nbsp;Magdalena Radulescu","doi":"10.1186/s12302-026-01447-z","DOIUrl":"10.1186/s12302-026-01447-z","url":null,"abstract":"<div><p>Export diversification and environmental innovations are widely regarded as key determinants of ecological sustainability. However, the economic gains of export diversification often come at the expense of ecological sustainability, as they tend to drive higher energy consumption through fossil fuel use and other polluting activities. To help address these challenges and add a novel contribution to existing literature, this study analyzes how environmental innovations moderate the impact of export diversification on ecological sustainability via load capacity factor across main trading developing economies (China, India, South Korea, Malaysia, Mexico, Russia, and Singapore) from 1995 to 2020. The empirical results show that export diversification, energy consumption, population, and financial markets efficiency negatively impact ecological sustainability. Regarding the interaction term, environmental innovation plays a significant role in converting the negative ecological effects of export diversification into positive outcomes. Furthermore, the relationship between economic growth and its squared term follows a U-shaped pattern, which validates the load capacity curve assumption. Therefore, this study highlights the importance for main trading developing economies of promoting export diversification and environmental innovation by simultaneously supporting the adoption of renewable energy technologies, low-carbon production techniques, and clean transport to achieve ecological sustainability.</p></div>","PeriodicalId":546,"journal":{"name":"Environmental Sciences Europe","volume":"38 1","pages":""},"PeriodicalIF":7.1,"publicationDate":"2026-06-22","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://link.springer.com/content/pdf/10.1186/s12302-026-01447-z.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148927907","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"环境科学与生态学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Energy taxation, urbanization, and eco-innovation as drivers of biodiversity protection during supply chain disruptions in France: evidence from wavelet quantile cointegration","authors":"Jing Han,&nbsp;Runguo Xu","doi":"10.1186/s12302-026-01439-z","DOIUrl":"10.1186/s12302-026-01439-z","url":null,"abstract":"<div><p>Biodiversity loss has profound impacts on environmental sustainability and a potentially destabilizing effect on the economy, yet few studies have considered the interaction between supply chain shocks and fiscal and innovation-based policies to affect biodiversity from distributional and time–frequency perspectives. This research seeks to examine the influence of supply chain shocks, taxation, human capital, urbanization, and eco-innovation on biodiversity in France between 1990Q1 and 2021Q4. To fill this gap, this research uses a wavelet-based quantile approach, Wavelet Quantile Cointegration (WQC), and Wavelet Granger Causality (WGC) to examine dynamic interactions at different time and distributional levels. Our results show that biodiversity is vulnerable to supply chain disruptions, burdened by energy taxation, and boosted by eco-innovation. Human capital positively impacts biodiversity in the long term, while urbanization negatively impacts it unless urban planning offers a solution. This highlights the importance of a comprehensive approach that includes fiscal, innovation, human capital, and urban planning measures to boost biodiversity resilience.</p></div>","PeriodicalId":546,"journal":{"name":"Environmental Sciences Europe","volume":"38 1","pages":""},"PeriodicalIF":7.1,"publicationDate":"2026-06-18","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://link.springer.com/content/pdf/10.1186/s12302-026-01439-z.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148927809","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"环境科学与生态学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Precision zoning and dominant factor identification of soil lead using a geographical pattern interaction model and POI data","authors":"Junfeng Qu,&nbsp;Xiangyang Feng,&nbsp;Xia Jia,&nbsp;Yaqiu Zhong,&nbsp;Qingwu Yan,&nbsp;Yiyun Chen,&nbsp;Zihao Wu","doi":"10.1186/s12302-026-01438-0","DOIUrl":"10.1186/s12302-026-01438-0","url":null,"abstract":"<div><p>Precision management of soil lead (Pb) in peri-urban areas requires accurately identifying pollution sources and their spatially varying influences. However, traditional land-use data are too coarse to pinpoint high-risk industries, and widely used ensemble learning models typically fail to explicitly reveal spatially varying driver effects, which is crucial for actionable environmental zoning. To address these gaps, this study developed a framework integrating Points of Interest (POI) and PM2.5 data for fine-scale characterization of industrial sources, and applied the Geographical Pattern Interaction (GPI) model for spatial partitioning and dominant factor identification. This framework was applied to Huangpi District, Wuhan city, China, a typical peri-urban area undergoing rapid industrialization. The GPI model demonstrated superior performance, significantly outperforming random forest and extreme gradient boosting in predictive accuracy (predicted R2 = 0.688) and effectively mitigating overfitting. Crucially, the model generated an optimal spatial partition, delineating six homogeneous subregions characterized by distinct Pb contamination level and dominant controlling factors. This partition revealed a clear spatial gradient: from northern uplands dominated by PM2.5 to southern industrial cores controlled by heavy industry emissions derived from POI kernel density, with transitional zones showing mixed influences. Furthermore, the GPI model quantified strong, spatially varying local interactions, particularly between industrial emissions and soil properties. Leveraging these mechanistic insights, we precisely delineated priority control zones and proposed targeted, threshold-based mitigation strategies. This work demonstrates that integrating POI data with the GPI model provides a powerful and interpretable framework for dominant factor identification and zoning management of soil heavy metals in complex peri-urban landscapes.</p></div>","PeriodicalId":546,"journal":{"name":"Environmental Sciences Europe","volume":"38 1","pages":""},"PeriodicalIF":7.1,"publicationDate":"2026-06-17","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://link.springer.com/content/pdf/10.1186/s12302-026-01438-0.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148837628","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"环境科学与生态学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Integrated toposequence-based assessment for sustainable agriculture in the vulnerable region of Bankura district, West Bengal: a GIS approach for food security and policy pathways","authors":"Indrajit Chowdhuri,&nbsp;Subodh Chandra Pal,&nbsp;Chaitanya Baliram Pande,&nbsp;Aznarul Islam,&nbsp;Abu Reza Md. Towfiqul Islam,&nbsp;Edris Alam,&nbsp;Md Kamrul Islam","doi":"10.1186/s12302-026-01444-2","DOIUrl":"10.1186/s12302-026-01444-2","url":null,"abstract":"<div><p>Toposequence analysis is essential for optimizing land use, improving soil and water management, enhancing crop productivity, and promoting climate-resilient agriculture. This study employs an Integrated Toposequence Analysis (ITA) framework to evaluate how variations in topography influence soil characteristics, fertility patterns, and cropping systems in Bankura district, located along the fringe of the Chhota Nagpur Plateau in West Bengal. The landscape was classified into upland, midland, and lowland zones using the weighted sum method, based on elevation, relative relief, and slope. Local soil classifications were further associated with the major Indian soil groups of red and yellow soil, lateritic soil, and alluvial soils. Soil chemical properties were analyzed, and a Soil Fertility (SF) map was generated using logistic regression, while Weaver’s crop combination method was applied to identify dominant cropping patterns. The results reveal a distinct fertility gradient across toposequence units: lowlands exhibit high fertility, uplands show moderate fertility, and midlands demonstrate relatively low fertility. Irrigation availability is most favorable in lowland agricultural fields, whereas upland regions remain predominantly mono-cropped with paddy. However, improved water management, diversification of cropping patterns, and modification of the crop calendar could significantly enhance yield potential in upland areas. The study highlights the importance of incorporating toposequence-based planning into agricultural decision-making and demonstrates that strategic interventions can strengthen soil productivity and food security. Overall, the findings contribute to sustainable agricultural development and support the achievement of UN Sustainable Development Goal 2 (Zero Hunger).</p></div>","PeriodicalId":546,"journal":{"name":"Environmental Sciences Europe","volume":"38 1","pages":""},"PeriodicalIF":7.1,"publicationDate":"2026-06-15","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://link.springer.com/content/pdf/10.1186/s12302-026-01444-2.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148782468","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"环境科学与生态学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Neo-institutional perspectives on academic freedoms and environmental sustainability: the roles of political stability and regulatory quality","authors":"Samuel Amponsah Odei","doi":"10.1186/s12302-026-01440-6","DOIUrl":"10.1186/s12302-026-01440-6","url":null,"abstract":"<div><p>While academic freedom is proven to spur innovation and inquiry, its association with environmental sustainability outcomes, proxied by greenhouse gas (GHG), remains underexplored. This study investigates the association between academic freedom and environmental sustainability and how this association is conditioned by political stability and regulatory quality across Organisation for Economic Co-operation and Development (OECD) countries from 1990 to 2023. Drawing on neo-institutional theory, we use panel data approaches such as fixed effects (FE) and two-step system Generalised Method of Moments (GMM) estimators to control for unobserved heterogeneity and endogeneity. The results reveal a negative association between academic freedom and environmental sustainability, implying that increased academic freedoms are associated with higher emissions. However, this association differs by context: it becomes positive under lower levels of political stability and is attenuated under higher levels of regulatory quality. These results imply that the association between academic freedom and environmental sustainability is contingent on existing institutional environments. The study contributes to the literature by accentuating the importance of considering governance contexts when examining the environmental effects of academic freedom, and proposes that blending institutional frameworks with academic freedom is indispensable for achieving environmental sustainability outcomes.</p></div>","PeriodicalId":546,"journal":{"name":"Environmental Sciences Europe","volume":"38 1","pages":""},"PeriodicalIF":7.1,"publicationDate":"2026-06-14","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://link.springer.com/content/pdf/10.1186/s12302-026-01440-6.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148782497","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"环境科学与生态学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Short-term exposure to polycyclic aromatic hydrocarbons and ocular surface Inflammation in primary school children","authors":"Yini Zhao,&nbsp;Chengpeng Huang,&nbsp;Xuefei Wang,&nbsp;Mingzhe Li,&nbsp;Yan Liu","doi":"10.1186/s12302-026-01437-1","DOIUrl":"10.1186/s12302-026-01437-1","url":null,"abstract":"<div><p>Polycyclic aromatic hydrocarbons (PAHs) are ubiquitous environmental contaminants with oxidative and pro-inflammatory properties. While systemic effects of PAHs have been widely documented, their short-term ocular impacts in children remain poorly understood. We evaluated the association between urinary PAH metabolites and ocular surface inflammation in a large school-based population in Shenyang, China. Between 2023 and 2024, 5100 children aged 7–10 years from 60 primary schools were examined. Eleven urinary hydroxylated PAH metabolites (OH-PAHs) were quantified using HPLC–MS/MS and adjusted for specific gravity. Ocular inflammation was assessed through standardized ophthalmologic examinations, including conjunctival redness, ocular discharge, eyelid swelling, and conjunctival edema. Multivariable logistic regression models estimated odds ratios (ORs) for each metabolite, adjusting for potential confounders. Mixture effects were further analyzed using generalized weighted quantile sum regression (gWQS) and g-computation. Elevated urinary concentrations of 2-hydroxynaphthalene, 1-hydroxynaphthalene, and 2-hydroxyfluorene were significantly associated with conjunctival redness (aOR range: 1.13–1.21, p &lt; 0.001). Ocular discharge was linked to 2-hydroxynaphthalene (aOR = 1.20, 95% CI 1.14–1.25) and 3-hydroxychrysene (aOR = 1.40, 95% CI 1.14–1.71), while eyelid swelling showed the strongest association with 1-hydroxypyrene (aOR = 1.70, 95% CI 1.37–2.11). Mixture analyses confirmed significant combined effects, with g-comp ORs of 1.71, 2.41, 2.31, and 1.43 for redness, discharge, swelling, and edema, respectively (all p &lt; 0.001). These findings indicate that short-term PAH exposure may trigger ocular surface inflammation in children, positioning conjunctivitis-related outcomes as early biomarkers of environmental toxicity. Further longitudinal and mechanistic research is needed to elucidate causal pathways and inform preventive strategies.</p></div>","PeriodicalId":546,"journal":{"name":"Environmental Sciences Europe","volume":"38 1","pages":""},"PeriodicalIF":7.1,"publicationDate":"2026-06-13","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://link.springer.com/content/pdf/10.1186/s12302-026-01437-1.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148837481","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"环境科学与生态学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Exposure to perfluorooctanoic acid promotes lung adenocarcinoma: mechanistic insights from multidimensional network analyses","authors":"Jiahong Hong,&nbsp;Xiaoxiang Rong,&nbsp;Jialin Gao,&nbsp;Xiaolin Li,&nbsp;Zetao Zuo,&nbsp;Rui Zhou,&nbsp;Huiying Sun,&nbsp;Zhenhua Huang","doi":"10.1186/s12302-026-01398-5","DOIUrl":"10.1186/s12302-026-01398-5","url":null,"abstract":"<div><p>Perfluorooctanoic acid (PFOA), a persistent environmental pollutant, has been increasingly implicated in lung cancer development, yet the molecular mechanisms linking PFOA exposure to lung adenocarcinoma (LUAD) remain unclear. This study employed an integrated, multidimensional framework combining epidemiology, computational toxicology, network analysis, machine learning, single-cell transcriptomics, and molecular docking to systematically explore the potential associations between PFOA exposure and LUAD pathogenesis. Serum PFOA and PFOS concentrations were analyzed in 5899 participants from the NHANES 2013–2020 dataset. Weighted logistic regression revealed a significant association between PFOA exposure and lung cancer risk (OR = 1.05 per unit increase in ln-transformed PFOA; 95% CI 1.01–1.09; p = 0.02), whereas PFOS showed no significant relationship. ADMETlab and ProTox predictions indicated multi-organ toxicity and carcinogenic potential of both compounds. Integrative toxicogenomics identified 248 overlapping genes between PFOA targets and LUAD differentially expressed genes, with protein–protein interaction analysis highlighting 20 hub genes. Functional enrichment implicated cell cycle regulation, chromosomal segregation, and p53 signaling as key pathways. A machine learning framework consistently identified CDCA8, TRIP13, CCNB2, and CDC20 as core diagnostic biomarkers with high sensitivity and specificity (AUC &gt; 0.90). Single-cell RNA sequencing revealed these genes were predominantly expressed in malignant epithelial and myeloid cells. Molecular docking confirmed stable, high-affinity interactions between PFOA and the four core proteins. Finally, a prognostic model based on six PFOA-LUAD-associated genes (GJB3, CPS1, EXO1, PLEK2, KRT6A, CDC25C) demonstrated robust predictive performance across multiple independent cohorts (average C-index = 0.763). Collectively, these findings provide novel mechanistic insights into the potential role of environmental PFOA exposure in LUAD development and identify potential diagnostic and prognostic biomarkers. The results have important public health implications, underscoring the need for regulatory measures to reduce PFAS exposure and informing risk assessment, early detection, and targeted intervention strategies.</p></div>","PeriodicalId":546,"journal":{"name":"Environmental Sciences Europe","volume":"38 1","pages":""},"PeriodicalIF":7.1,"publicationDate":"2026-06-12","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://link.springer.com/content/pdf/10.1186/s12302-026-01398-5.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148782353","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"环境科学与生态学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Pesticide accumulation in tissues of cultured Oreochromis niloticus and Mugil cephalus: effects on biochemical biomarkers and associated human health risks","authors":"Asmaa M. El-Agri,&nbsp;Hamed H. E. Saleh,&nbsp;Mohamed A. Elokaby,&nbsp;Hala Saber Khalil,&nbsp;Nehal M. N. Elkhouly,&nbsp;Ahmed Abdelaal,&nbsp;Mohammed F. El Basuini,&nbsp;Abdelaziz M. Nour,&nbsp;Mohamed A. Zaki,&nbsp;Fatma Ragab Abouel Azm,&nbsp;Rasha K. Abdel-Wahed,&nbsp;Gad H. G. Hussein","doi":"10.1186/s12302-026-01432-6","DOIUrl":"10.1186/s12302-026-01432-6","url":null,"abstract":"<div><h3>Background</h3><p>Egypt's food security depends heavily on aquaculture, however fish farmed on farms that receive agricultural drainage water may be subjected to pesticide pollution. Such contamination can impair fish health, alter physiological functions, and pose potential risks to consumers. This study investigated the occurrence and distribution of pesticide residues in water and in the gill, liver, and muscle tissues of two economically important species, <i>Oreochromis niloticus</i> and <i>Mugil cephalus</i>, collected from four fish farms that differ in their water sources in Fayoum Governorate, Egypt. The control farm was irrigated with fresh water, while the other farms were irrigated with agricultural drainage water. It also evaluated the biochemical and stress-related responses in fish and assessed potential risks associated with human consumption.</p><h3>Results</h3><p>Farms supplied with drainage water exhibited higher salinity and nutrient pollution compared to the freshwater control farm. Multiple classes of pesticides, including organochlorine insecticides, pyrethroid insecticides, and herbicides, were detected in both water and fish tissues, with the highest concentrations found at the El-Bats and Dayer El-Berka farms. Pesticide accumulation varied by species and organ: <i>O. niloticus</i> accumulated the highest levels in the liver, whereas <i>M. cephalus</i> accumulated more in the gills. Fish from polluted farms showed reduced activities of the liver enzymes aspartate aminotransferase and alanine aminotransferase, alongside increased concentrations of triglycerides, cholesterol, and total lipids in muscle tissue. Oxidative and cellular stress markers, including malondialdehyde and caspase-12, were elevated in all examined tissues, while catalase activity was reduced.</p><h3>Conclusions</h3><p>Fish raised in agriculture drainage-fed aquaculture systems showed clear evidence of pesticide exposure, organ-specific accumulation patterns, and associated biochemical and stress responses. Despite exceedances of regulatory residue limits for some compounds, the overall dietary risk to consumers was found to be low based on estimated intake calculations. Nevertheless, the high prevalence of pesticide mixtures in water and fish highlights the need for continuous monitoring and management of agricultural runoff to maintain aquaculture productivity and ensure safe consumption.</p></div>","PeriodicalId":546,"journal":{"name":"Environmental Sciences Europe","volume":"38 1","pages":""},"PeriodicalIF":6.0,"publicationDate":"2026-06-11","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://link.springer.com/content/pdf/10.1186/s12302-026-01432-6.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148236646","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"环境科学与生态学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}