Retina-The Journal of Retinal and Vitreous Diseases最新文献_第6页

Purtscher-Like Retinopathy and Acute Macular Neuroretinopathy in a Child with Acute Influenza A. 一名急性甲型流感患儿的紫癜样视网膜病变和急性黄斑神经视网膜病变

IF 2.3 2区医学

Retina-The Journal of Retinal and Vitreous Diseases Pub Date : 2024-10-01 DOI: 10.1097/IAE.0000000000004095

Malcolm M Kates, Timothy P Sipos, Russell W Read, Matthew H Oltmanns

引用次数: 0

Three-dimensional Hill of Vision of Retinal Sensitivity in X-linked Retinitis Pigmentosa Participants under Scotopic and Mesopic Conditions. X 连锁视网膜色素变性参与者在苏格米氏和中视条件下视网膜灵敏度的三维视觉山丘。

IF 2.3 2区医学

Retina-The Journal of Retinal and Vitreous Diseases Pub Date : 2024-09-25 DOI: 10.1097/IAE.0000000000004278

Antonio Yaghy, A Yasin Alibhai, Lucas R De Pretto, Darin Curtiss, David G Birch, Nadia K Waheed

{"title":"Three-dimensional Hill of Vision of Retinal Sensitivity in X-linked Retinitis Pigmentosa Participants under Scotopic and Mesopic Conditions.","authors":"Antonio Yaghy, A Yasin Alibhai, Lucas R De Pretto, Darin Curtiss, David G Birch, Nadia K Waheed","doi":"10.1097/IAE.0000000000004278","DOIUrl":"https://doi.org/10.1097/IAE.0000000000004278","url":null,"abstract":"Purpose: To evaluate the utility of three-dimensional hill of vision (HOV) analysis in assessing retinal sensitivity in X-linked retinitis pigmentosa (XLRP) patients under scotopic cyan, scotopic red, and mesopic microperimetry conditions.Methods: Baseline microperimetry data from 31 eyes of 16 XLRP patients enrolled in the Horizon study were analyzed. HOVs were generated using Thin Plate Spline interpolation. Grid volumes of the central 20 degrees (V20) were compared between lighting conditions using the Wilcoxon Signed-Rank test with Bonferroni correction. Central and global deficits were evaluated across age groups and genotypes.Results: The mesopic group showed the highest mean V20 (1.3 dB-Sr), followed by scotopic red (0.6 dB-Sr) and scotopic cyan (0.5 dB-Sr). Significant differences were found between mesopic and both scotopic conditions (p<0.01), but not between scotopic conditions (p=0.26). Central and global deficits were more prevalent under scotopic conditions and increased with age.Conclusion: HOV analysis provides a comprehensive assessment of retinal sensitivity in XLRP, enabling detection of localized changes and quantification of sensitivity gradients. This volumetric approach offers advantages over traditional methods for diagnosis, monitoring progression, and evaluating treatment response.","PeriodicalId":54486,"journal":{"name":"Retina-The Journal of Retinal and Vitreous Diseases","volume":" ","pages":""},"PeriodicalIF":2.3,"publicationDate":"2024-09-25","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142332470","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Quantification of capillary blood flow speeds in diabetic retinopathy using variable interscan time analysis (VISTA) OCTA. 利用可变扫描间时间分析（VISTA）OCTA 对糖尿病视网膜病变中的毛细血管血流速度进行量化。

IF 2.3 2区医学

Retina-The Journal of Retinal and Vitreous Diseases Pub Date : 2024-09-25 DOI: 10.1097/IAE.0000000000004279

Yunchan Hwang, Hiroyuki Takahashi, Jungeun Won, Antonio Yaghy, Anna Marmalidou, Stephanie M Kaiser, Muhammad Usman Jamil, Caroline R Baumal, Nadia K Waheed, James G Fujimoto

{"title":"Quantification of capillary blood flow speeds in diabetic retinopathy using variable interscan time analysis (VISTA) OCTA.","authors":"Yunchan Hwang, Hiroyuki Takahashi, Jungeun Won, Antonio Yaghy, Anna Marmalidou, Stephanie M Kaiser, Muhammad Usman Jamil, Caroline R Baumal, Nadia K Waheed, James G Fujimoto","doi":"10.1097/IAE.0000000000004279","DOIUrl":"https://doi.org/10.1097/IAE.0000000000004279","url":null,"abstract":"Purpose: To investigate retinal capillary plexus capillary flow speed and vessel density in diabetic retinopathy (DR) and normal subjects using variable interscan time analysis (VISTA) optical coherence tomography angiography (OCTA).Methods: High speed swept source OCTA imaging using multiple interscan times was performed over a 5 mm x 5 mm field-of-view with 600 kHz A-scan rate. Second-generation VISTA OCTA was used to measure a surrogate marker for capillary blood flow speed, VISTA flow speed (VFS), in the superficial and intermediate capillary plexuses, (SCP + ICP)VFS, and deep capillary plexus, DCPVFS. Vessel density was measured using OCTA.Results: Fifty-seven eyes with different DR severity and 37 normal eyes were analyzed. VISTA OCTA provided diverse blood flow speed information, including pseudo-color OCTA and mean flow speed in different regions. Both DCPVFS and DCPVFS/(SCP + ICP)VFS were higher in DR compared to normal eyes. Elevated DCPVFS correlated with decreased DCP vessel density in non-proliferative DR.Conclusion: VISTA OCTA can measure a quantitative biomarker for blood flow speed alterations in DR and normal eyes as well as the association with vessel density in different capillary plexuses. VISTA OCTA is promising for studies of pathogenesis and early flow alterations which may precede non-perfusion.","PeriodicalId":54486,"journal":{"name":"Retina-The Journal of Retinal and Vitreous Diseases","volume":" ","pages":""},"PeriodicalIF":2.3,"publicationDate":"2024-09-25","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142332469","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Macular Hole Surgery and Retinal Tectonics: The Impact of Internal Limiting Membrane Peeling Size on Tangential Retinal Displacement. 黄斑孔手术与视网膜构造：内限制膜剥离尺寸对视网膜切向位移的影响

IF 2.3 2区医学

Retina-The Journal of Retinal and Vitreous Diseases Pub Date : 2024-09-25 DOI: 10.1097/IAE.0000000000004276

Marco Pellegrini, Ginevra Adamo, Chiara Vivarelli, Alice Bizzarri, Riccardo Mondin, Pietro Maria Talli, Francesco Nasini, Giuseppe Giannaccare, Marco Mura

{"title":"Macular Hole Surgery and Retinal Tectonics: The Impact of Internal Limiting Membrane Peeling Size on Tangential Retinal Displacement.","authors":"Marco Pellegrini, Ginevra Adamo, Chiara Vivarelli, Alice Bizzarri, Riccardo Mondin, Pietro Maria Talli, Francesco Nasini, Giuseppe Giannaccare, Marco Mura","doi":"10.1097/IAE.0000000000004276","DOIUrl":"https://doi.org/10.1097/IAE.0000000000004276","url":null,"abstract":"Purpose: The aim of the study was to evaluate the tangential retinal displacement occurring following macular hole surgery, and to assess the impact of the internal limiting membrane (ILM) peeling size on the extent of the retinal movement.Methods: This retrospective study included patients with full-thickness macular hole undergoing 25-gauge pars plana vitrectomy with ILM peeling. Patients received either a small ILM peeling with a size of 2-disc diameters or a large peeling extended up to the vascular arcades. Near-infrared retinal imaging was performed with the Spectralis (Heidelberg Engineering, Carlsbad, Germany) before and 6 months after surgery. The tangential retinal displacement was evaluated comparing the optical flow of near-infrared images with a custom digital image analysis algorithm.Results: 44 eyes of 44 patients undergoing vitrectomy with small (n = 24) or large (n = 20) ILM peeling were included. An average overall displacement of 31.3 ± 22.8 µm towards the optic disc was observed after surgery. Large ILM peeling was associated with a significantly higher overall displacement (P = 0.009), displacement in the central 4-mm circle (P < 0.001) and outer 8-mm ring (P = 0.001). Macular holes closure was achieved in 100% and 83.3% of patients in the large and small peeling group, respectively (P = 0.055).Conclusions: Pars plana vitrectomy with ILM peeling for macular hole results in a tangential retinal displacement towards the optic disc. A larger extent of the ILM peeling leads to a greater tangential movement, possibly improving the macular hole closure rate.","PeriodicalId":54486,"journal":{"name":"Retina-The Journal of Retinal and Vitreous Diseases","volume":" ","pages":""},"PeriodicalIF":2.3,"publicationDate":"2024-09-25","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142332466","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Unilateral Idiopathic Progressive Subretinal fibrosis: Imaging characteristics. 单侧特发性进行性视网膜下纤维化：影像学特征。

IF 2.3 2区医学

Retina-The Journal of Retinal and Vitreous Diseases Pub Date : 2024-09-25 DOI: 10.1097/IAE.0000000000004277

Anamika Patel, Anup Kelgaonkar, Avinash Pathengay

引用次数: 0

Macular Volume Scan as a Marker of Angiographic Uveitic Retinal Vasculitis: A Retrospective Longitudinal Study. 作为血管造影葡萄膜视网膜血管炎标志的黄斑体积扫描：一项回顾性纵向研究

IF 2.3 2区医学

Retina-The Journal of Retinal and Vitreous Diseases Pub Date : 2024-09-24 DOI: 10.1097/IAE.0000000000004275

Akhila Alapati, Saleema Kherani, Tedi Begaj, Timothy M Janetos, Kevin Zhang, Anjum Koreishi, Debra A Goldstein

{"title":"Macular Volume Scan as a Marker of Angiographic Uveitic Retinal Vasculitis: A Retrospective Longitudinal Study.","authors":"Akhila Alapati, Saleema Kherani, Tedi Begaj, Timothy M Janetos, Kevin Zhang, Anjum Koreishi, Debra A Goldstein","doi":"10.1097/IAE.0000000000004275","DOIUrl":"https://doi.org/10.1097/IAE.0000000000004275","url":null,"abstract":"Purpose: To determine whether optical coherence tomography (OCT) thickness values from macular volume scans can be used to detect uveitic retinal vasculitis.Methods: Retrospective study of patients with noninfectious retinal vasculitis. Fluorescein angiogram (FA) and 61-line OCT macular volume scans with an overlying Early Treatment Diabetic Retinopathy study (ETDRS) grid were obtained. Correlation between 1mm and 6mm ETDRS ring values and posterior pole vasculitis was analyzed. A linear longitudinal model was used to assess the relationship between global retinal vasculitis scores and OCT macular thickness parameters.Results: Ninety-nine eyes of 54 patients were included. A total of 460 OCT and fluorescein angiogram pairs were analyzed. Central (1mm) macular thickness was weakly correlated with posterior pole vasculitis (correlation coefficient [rho]=0.09, p=0.06). Both the mean 6mm ring (rho=0.11, p=0.018) and the average of the superior and inferior (S/I) 6mm ring values (rho=0.13, p=0.006) were strongly correlated with posterior pole leakage. The longitudinal model showed that S/I 6mm ring values are associated with vasculitis in the posterior pole, mid and far periphery (p<0.0001).Conclusions: OCT-based macular volume thickness can detect uveitic retinal vasculitis and aid in monitoring disease activity.","PeriodicalId":54486,"journal":{"name":"Retina-The Journal of Retinal and Vitreous Diseases","volume":" ","pages":""},"PeriodicalIF":2.3,"publicationDate":"2024-09-24","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142332467","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Anterior Subtenon Triamcinolone Injection for Refractory Macular Edema: A Retrospective Case Series. 前腱膜下注射曲安奈德治疗难治性黄斑水肿：回顾性病例系列。

IF 2.3 2区医学

Retina-The Journal of Retinal and Vitreous Diseases Pub Date : 2024-09-24 DOI: 10.1097/IAE.0000000000004274

Tina Felfeli, Megan Park, Nathan S Gorfinkel, Robert Shwarzman, John Papanikolaou, Paresh Shah, Alex Kiss, Efrem D Mandelcorn

{"title":"Anterior Subtenon Triamcinolone Injection for Refractory Macular Edema: A Retrospective Case Series.","authors":"Tina Felfeli, Megan Park, Nathan S Gorfinkel, Robert Shwarzman, John Papanikolaou, Paresh Shah, Alex Kiss, Efrem D Mandelcorn","doi":"10.1097/IAE.0000000000004274","DOIUrl":"https://doi.org/10.1097/IAE.0000000000004274","url":null,"abstract":"Purpose: To evaluate the effectiveness of anterior subtenon triamcinolone (AST) injections in the management of refractory macular edema.Methods: This is a retrospective case series of consecutive eyes with refractory macular edema treated with AST at a single vitreoretinal surgeon's practice at Toronto Western Hospital, University of Toronto, Canada in 2018-2023. Refractory was defined as persistent macular edema with a central subfield thickness of 250μm or greater over a 24-week period, receiving at least four intravitreal anti-VEGF injections. Vision outcomes and optical coherence tomography features for all eyes were compared for three visits pre-AST treatment and two visits post-AST treatment.Results: Ninety-three patients (119 eyes; diabetic macular edema (26%), and pseudophakic CME (74%), with a mean follow-up duration of 161 days were included. The presence of subretinal fluid (p=0.0013), central subfield macular thickness (p<0.0001), cube average thickness (p=0.0024) and macular cube volume (p= 0.0017) significantly improved from pre-AST to post-AST treatment. Visual acuity also significantly improved from pre-AST treatment to post-AST treatment (p<0.0001). There was no significant change in the intraocular pressures from pre-AST to post-AST (p=0.7920) and no complications were noted throughout the follow-up period.Conclusion: The findings from this study suggest that AST injections show modest improvement in anatomical and functional outcomes, and are safe for the treatment and management of refractory macular edema.","PeriodicalId":54486,"journal":{"name":"Retina-The Journal of Retinal and Vitreous Diseases","volume":" ","pages":""},"PeriodicalIF":2.3,"publicationDate":"2024-09-24","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142332414","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Optimizing surgical performance and safety in endoresection of uveal melanoma. 优化葡萄膜黑色素瘤内切术的手术性能和安全性。

IF 2.3 2区医学

Retina-The Journal of Retinal and Vitreous Diseases Pub Date : 2024-09-24 DOI: 10.1097/IAE.0000000000004273

Mario R Romano, Mariantonia Ferrara, Alessandro Feo, Anna Merico, Martina Angi

{"title":"Optimizing surgical performance and safety in endoresection of uveal melanoma.","authors":"Mario R Romano, Mariantonia Ferrara, Alessandro Feo, Anna Merico, Martina Angi","doi":"10.1097/IAE.0000000000004273","DOIUrl":"https://doi.org/10.1097/IAE.0000000000004273","url":null,"abstract":"Purpose: To present a standardized surgical technique for endoresection of uveal melanoma (UM) minimizing the risk of serious adverse events, including fatal gas embolism.Methods: Ten UM patients underwent endoresection following proton beam radiotherapy for radiotherapy-related vascular complications. Vortex veins located in correspondence of the tumor base had been cauterized at the time of tantalum markers placement. Endoresection was performed following complete 25G vitrectomy, endolaser and endodiathermy. The tumor was removed using a subretinal or transretinal approach depending on retinal infiltration. If needed, perfluorodecalin (PFD) was injected to stabilise the retina. Fluid-silicone oil (SO) or PFD-SO exchange was performed, avoiding air.Results: Endoresection was successfully performed in all eyes with no intraoperative complications. Mean follow-up (FU) was 10.8 ± 3.2 months. One patient was enucleated due to neovascular glaucoma. At the last FU, the remaining patients had the eye preserved and no signs of local recurrence or neovascular glaucoma.Conclusion: Our standardized surgical technique for UM endoresection appeared to be safe, minimizing the risk of serious intraoperative and postoperative adverse events.","PeriodicalId":54486,"journal":{"name":"Retina-The Journal of Retinal and Vitreous Diseases","volume":" ","pages":""},"PeriodicalIF":2.3,"publicationDate":"2024-09-24","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142332468","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Incidence of Steroid-Related Ocular Hypertension and Cataract Formation After Subtenon Triamcinolone in Non-Uveitic Pediatric Patients. 非葡萄膜炎儿科患者瞳孔下注射曲安奈德后类固醇相关性眼压升高和白内障形成的发生率。

IF 2.3 2区医学

Retina-The Journal of Retinal and Vitreous Diseases Pub Date : 2024-09-19 DOI: 10.1097/IAE.0000000000004272

Nimesh A Patel, Sandra Hoyek, Francisco J López-Font, Serena Shah, Sierra Ha, Natasha F S da Cruz, Daniel M Vu, Ta Chen Chang, Audina M Berrocal

{"title":"Incidence of Steroid-Related Ocular Hypertension and Cataract Formation After Subtenon Triamcinolone in Non-Uveitic Pediatric Patients.","authors":"Nimesh A Patel, Sandra Hoyek, Francisco J López-Font, Serena Shah, Sierra Ha, Natasha F S da Cruz, Daniel M Vu, Ta Chen Chang, Audina M Berrocal","doi":"10.1097/IAE.0000000000004272","DOIUrl":"https://doi.org/10.1097/IAE.0000000000004272","url":null,"abstract":"Purpose: To describe intraocular pressure (IOP) changes after injection of subtenon triamcinolone (STT) during examination under anesthesia (EUA) for pediatric patients.Methods: Multicenter, retrospective case series of pediatric patients STT from three tertiary care ophthalmic services between November 2018 and October 2023.Results: Of 392 patients identified, 59 eyes of 41 patients (10.5%) were included. Laser was administered in 95.1% of the cases. STT dose ranged from 4 to 20 mg. The most common diagnosis was retinopathy of prematurity (43.9%). Two eyes (3.4%) of 2 patients (4.9%) were mild steroid responders. One eye (1.7%) of 1 patient (2.4%) was a moderate responder. There were no high steroid responders, and all eyes with steroid response showed a return of IOP to normal range at next visit without needing any IOP-lowering medications. No patients were diagnosed with glaucoma or required glaucoma surgery. Only 1 eye (1.7%) developed trace posterior subcapsular cataract, while no optic disc cupping or inflammation were noted.Conclusions: Subtenon triamcinolone injection is commonly used to prevent inflammation at the time of retinal photocoagulation treatment in pediatric patients. It has a favorable safety profile in relation to IOP elevation and cataract formation. There was no requirement for IOP lowering medications or surgical interventions.","PeriodicalId":54486,"journal":{"name":"Retina-The Journal of Retinal and Vitreous Diseases","volume":" ","pages":""},"PeriodicalIF":2.3,"publicationDate":"2024-09-19","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142332415","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Letter to the Editor: LIGHTSITE III: 13-Month Efficacy and Safety Evaluation of Multiwavelength Photobiomodulation in Nonexudative (Dry) Age-Related Macular Degeneration Using the LumiTheraTM Valeda Light Delivery System. 致编辑的信LIGHTSITE III：使用 LumiTheraTM Valeda 光传输系统对非渗出性（干性）年龄相关性黄斑变性进行为期 13 个月的多波长光生物调节的疗效和安全性评估。

IF 2.3 2区医学

Retina-The Journal of Retinal and Vitreous Diseases Pub Date : 2024-09-19 DOI: 10.1097/IAE.0000000000004265

Nicolas Feltgen, Thomas Ach, Ulrich Bartz-Schmidt, Nikolaos Bechrakis, Nicole Eter, Lars Hattenbach, Heinrich Heimann, Hans Hoerauf, Albrecht Lommatzsch, Siegfried Priglinger, Andreas Stahl, Peter Walter, Armin Wolf, Focke Ziemssen, Salvatore Grisanti

引用次数: 0