Outcomes of Descemet Membrane Epiretinal Graft for Refractory Macular Hole Closure.

IF 2.3 2区医学 Q2 OPHTHALMOLOGY

Retina-The Journal of Retinal and Vitreous Diseases Pub Date : 2025-03-05 DOI:10.1097/IAE.0000000000004448

Marco Pellegrini, Angeli Christy Yu, Cristina Bovone, Ginevra Adamo, Pietro Maria Talli, Francesco Nasini, Diego Ponzin, Massimo Busin, Marco Mura

{"title":"Outcomes of Descemet Membrane Epiretinal Graft for Refractory Macular Hole Closure.","authors":"Marco Pellegrini, Angeli Christy Yu, Cristina Bovone, Ginevra Adamo, Pietro Maria Talli, Francesco Nasini, Diego Ponzin, Massimo Busin, Marco Mura","doi":"10.1097/IAE.0000000000004448","DOIUrl":null,"url":null,"abstract":"Purpose: To report the visual and anatomical outcomes of Descemet membrane epiretinal graft for refractory full-thickness macular holes (MH).Methods: This interventional case series included patients with refractory MH who previously underwent standard pars plana vitrectomy with internal limiting membrane peeling for repair of MH with no success. Donor corneas unsuitable for keratoplasty were stripped at the Eye Bank. The corneo-scleral button was stained with blue dye, punched to obtain a 2-mm Descemet membrane graft which was positioned over the MH. At the end of surgery, 20% sulfur hexafluoride gas tamponade was administered.Results: Twelve eyes of 12 patients with a mean follow-up of 8 ± 4 months were included. The MH closure rate was 91.7%. Best-corrected visual acuity significantly improved from 1.09 ± 0.56 preoperatively to 0.46 ± 0.54 logMAR (20/63 Snellen) after surgery (P = 0.006). The external limiting membrane and ellipsoid zone recovery rates were 33.3% and 41.7%, respectively.Conclusions: Descemet membrane epiretinal graft leads to satisfactory anatomic and visual outcomes for eyes with refractory MH.","PeriodicalId":54486,"journal":{"name":"Retina-The Journal of Retinal and Vitreous Diseases","volume":" ","pages":""},"PeriodicalIF":2.3000,"publicationDate":"2025-03-05","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"0","resultStr":null,"platform":"Semanticscholar","paperid":null,"PeriodicalName":"Retina-The Journal of Retinal and Vitreous Diseases","FirstCategoryId":"3","ListUrlMain":"https://doi.org/10.1097/IAE.0000000000004448","RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"Q2","JCRName":"OPHTHALMOLOGY","Score":null,"Total":0}

引用次数: 0

Abstract

Purpose: To report the visual and anatomical outcomes of Descemet membrane epiretinal graft for refractory full-thickness macular holes (MH).

Methods: This interventional case series included patients with refractory MH who previously underwent standard pars plana vitrectomy with internal limiting membrane peeling for repair of MH with no success. Donor corneas unsuitable for keratoplasty were stripped at the Eye Bank. The corneo-scleral button was stained with blue dye, punched to obtain a 2-mm Descemet membrane graft which was positioned over the MH. At the end of surgery, 20% sulfur hexafluoride gas tamponade was administered.

Results: Twelve eyes of 12 patients with a mean follow-up of 8 ± 4 months were included. The MH closure rate was 91.7%. Best-corrected visual acuity significantly improved from 1.09 ± 0.56 preoperatively to 0.46 ± 0.54 logMAR (20/63 Snellen) after surgery (P = 0.006). The external limiting membrane and ellipsoid zone recovery rates were 33.3% and 41.7%, respectively.

Conclusions: Descemet membrane epiretinal graft leads to satisfactory anatomic and visual outcomes for eyes with refractory MH.

查看原文本刊更多论文

求助全文

约1分钟内获得全文求助全文

来源期刊

Retina-The Journal of Retinal and Vitreous Diseases 医学-眼科学

CiteScore

5.70

自引率

9.10%

发文量

554

审稿时长

3-6 weeks

期刊介绍： RETINA® focuses exclusively on the growing specialty of vitreoretinal disorders. The Journal provides current information on diagnostic and therapeutic techniques. Its highly specialized and informative, peer-reviewed articles are easily applicable to clinical practice. In addition to regular reports from clinical and basic science investigators, RETINA® publishes special features including periodic review articles on pertinent topics, special articles dealing with surgical and other therapeutic techniques, and abstract cards. Issues are abundantly illustrated in vivid full color. Published 12 times per year, RETINA® is truly a “must have” publication for anyone connected to this field.