Sebastian Nudleman, Ella R Feiner, Stella Affeldt, Jonathan L Prenner
{"title":"Office-Based 25-Gauge Needle Revision of Closed Peripheral Iridotomy in Aphakic Silicone Oil-Filled Eyes.","authors":"Sebastian Nudleman, Ella R Feiner, Stella Affeldt, Jonathan L Prenner","doi":"10.1097/IAE.0000000000004464","DOIUrl":"https://doi.org/10.1097/IAE.0000000000004464","url":null,"abstract":"<p><strong>Purpose: </strong>We present a novel office-based technique using a 25-gauge needle to reopen closed peripheral iridotomies (PIs) in aphakic eyes filled with silicone oil.</p><p><strong>Methods: </strong>We use a 25-gauge needle to enter the clear cornea and reopen the closed PI, allowing for aqueous humor and silicone oil to escape and relieve elevated intraocular pressure (IOP).</p><p><strong>Results: </strong>This minimally invasive office-based approach provides immediate relief of elevated IOP due to silicone oil-induced pupillary block, avoiding the need for more invasive surgical intervention.</p><p><strong>Conclusion: </strong>Our technique is a simple, cost-effective, and accessible way to combat silicone-oil induced pupillary block in aphakic patients and may be a good first-line approach for a difficult-to-manage condition.</p>","PeriodicalId":54486,"journal":{"name":"Retina-The Journal of Retinal and Vitreous Diseases","volume":" ","pages":""},"PeriodicalIF":2.3,"publicationDate":"2025-03-24","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143712133","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Akhila Alapati, Saleema Kherani, Tedi Begaj, Timothy M Janetos, Kevin Zhang, Anjum Koreishi, Debra A Goldstein
{"title":"Re: Letter to Editor: Addressing Inter-eye Correlation in Retinal Image Analysis for Patients with Bilateral Data.","authors":"Akhila Alapati, Saleema Kherani, Tedi Begaj, Timothy M Janetos, Kevin Zhang, Anjum Koreishi, Debra A Goldstein","doi":"10.1097/IAE.0000000000004468","DOIUrl":"https://doi.org/10.1097/IAE.0000000000004468","url":null,"abstract":"","PeriodicalId":54486,"journal":{"name":"Retina-The Journal of Retinal and Vitreous Diseases","volume":" ","pages":""},"PeriodicalIF":2.3,"publicationDate":"2025-03-11","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143671719","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Novel technique for macular hole-associated retinal detachment with inverted internal limiting membrane flap technique under perfluorocarbon liquid.","authors":"Jiro Kogo, Kazuhito Yoneda, Takeshi Iwase","doi":"10.1097/IAE.0000000000004465","DOIUrl":"https://doi.org/10.1097/IAE.0000000000004465","url":null,"abstract":"<p><strong>Purpose: </strong>To describe the technique and surgical outcomes of a modified inverted internal limiting membrane (ILM) flap technique, using perfluorocarbon liquid (PFCL) without creating iatrogenic retinal breaks in the management of macular hole-associated retinal detachment (MHRD).</p><p><strong>Methods: </strong>This retrospective study was approved by the Ethics Committee of Akita University Hospital. Eight patients with MHRD underwent pars plana vitrectomy (PPV) with the novel PFCL-assisted inverted ILM flap technique. Subretinal fluid was drained through the macular hole using a soft-tip needle, and ILM staining was performed after fluid-air exchange. PFCL was applied to stabilize the retina, and ILM peeling was completed under PFCL with improved visibility. The procedure concluded with air-fluid exchange and tamponade using silicone oil or gas. Patients maintained a face-down position postoperatively for one day.</p><p><strong>Results: </strong>All eight patients achieved initial retinal reattachment and macular hole closure without intraoperative or postoperative complications. After over 12 months of follow-up, macular hole closure and retinal reattachment were maintained in all cases.</p><p><strong>Discussion: </strong>Our novel technique avoids iatrogenic breaks, reducing ERM risk and secondary macular hole formation. The PFCL-assisted ILM manipulation ensures stability and minimizes retinal damage. The method is safe, effective, and promising for MHRD treatment in this small series.</p>","PeriodicalId":54486,"journal":{"name":"Retina-The Journal of Retinal and Vitreous Diseases","volume":" ","pages":""},"PeriodicalIF":2.3,"publicationDate":"2025-03-11","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143671619","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Bo-Een Hwang, Mirinae Kim, Young Geun Park, Young-Hoon Park
{"title":"Assessment of Choroidal Vascular Alterations in Branch Retinal Vein Occlusion Using Wide-Field Indocyanine Green and Fluorescein Angiography.","authors":"Bo-Een Hwang, Mirinae Kim, Young Geun Park, Young-Hoon Park","doi":"10.1097/IAE.0000000000004469","DOIUrl":"https://doi.org/10.1097/IAE.0000000000004469","url":null,"abstract":"<p><strong>Purpose: </strong>To quantitatively analyze choroidal vascular characteristics in branch retinal vein occlusion (BRVO) using wide-field indocyanine green angiography (wICG) and fluorescein angiography (wFA).</p><p><strong>Methods: </strong>Retrospective analysis of 66 eyes (33 unilateral BRVO patients, including fellow eyes) was conducted. Quantitative measures included fractal dimension (FD), lacunarity (LAC), choroidal vessel density (CVD), total vessel length (TVL), mean vessel diameter (MVD), and blood vessel tortuosity (BVT). To minimize retinal vessel influence, FD and LAC were calculated using wICG/wFA ratios (FD_r, LAC_r) and wICG-wFA differences (△FD, △LAC). Other parameters were obtained by subtracting wFA from wICG values.</p><p><strong>Results: </strong>In BRVO-affected eyes, FD_r, △FD, CVD, and macular CVI were significantly lower than in fellow eyes (p=0.029, p=0.027, p<0.001, p=0.043). △FD correlated with choroidal thickness (CT) and Haller/Choroid thickness ratio (H/C) (r=-0.380/p=0.029, ρ=0.364/p=0.038). △FD was lower in good responders to intravitreal injection (p=0.041), and final visual acuity correlated with TVL, MVD, and BVT (β/p = 0.481/0.005, -0.386/0.027, 0.430/0.012).</p><p><strong>Conclusion: </strong>Changes in vascular parameters in BRVO suggest choroidal remodeling driven by stromal congestion as an alternative mechanism rather than solely VEGF-driven choroidal alterations. These findings enhance understanding of choroidal dynamics and aid in predicting visual prognosis and treatment response.</p>","PeriodicalId":54486,"journal":{"name":"Retina-The Journal of Retinal and Vitreous Diseases","volume":" ","pages":""},"PeriodicalIF":2.3,"publicationDate":"2025-03-11","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143671600","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Unnikrishnan Nair, Indu Nair, Jay Sheth, Manoj Soman
{"title":"The Imaging Correlation between outer retina-associated hyperreflectivity and outer retinal and choroidal microvascular changes in Macular Telangiectasia type 2.","authors":"Unnikrishnan Nair, Indu Nair, Jay Sheth, Manoj Soman","doi":"10.1097/IAE.0000000000004466","DOIUrl":"https://doi.org/10.1097/IAE.0000000000004466","url":null,"abstract":"<p><strong>Purpose: </strong>To elucidate outer-retinal choroidal microvascular abnormalities (ORCMA) observed in Macular Telangiectasia type 2 (MacTel 2), particularly in association with outer retina-associated hyperreflectivity (ORaH).</p><p><strong>Methods: </strong>Retrospective analysis of 60 eyes with MacTel 2 having ORaH was conducted. OCT and OCTA images were meticulously reviewed to identify ORCMA patterns.</p><p><strong>Results: </strong>All 60 eyes exhibited hyperreflective foci (HRF), with varying incidences of subsidence, ellipsoid zone (EZ) loss, pigment clumps, cystoids, and double-layer sign (DLS). Vascular invasion, retinochoroidal anastomosis (RCA), and macular neovascularization (MNV) were observed, with all cases demonstrating ORaH. OCTA revealed microvascular changes. Subsidence correlated significantly with invasion (P=0.009), while pigment clumps, cystoids, and DLS were not significant. RCA was associated with pigment clumps, cystoids, and DLS (P<0.05), whereas MNV correlated with subsidence (P=0.022).</p><p><strong>Conclusion: </strong>The study delineates ORCMA in MacTel 2, identifying three patterns: vascular invasion, RCA, and MNV. Vascular invasion affects the outer retina, potentially leading to subsidence. RCA, a pre-proliferative stage, involves anastomosis between retinal and choroidal microvasculature, associated with pigment clumps, cystoids, and DLS. MNV, an advanced stage, exhibits extensions below the RPE and exudation, suggesting a continuum from invasion to neovascularization. Recognizing these stages aids in diagnosis, prognosis, and intervention development for MacTel 2.</p>","PeriodicalId":54486,"journal":{"name":"Retina-The Journal of Retinal and Vitreous Diseases","volume":" ","pages":""},"PeriodicalIF":2.3,"publicationDate":"2025-03-10","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143665252","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
S Garrison Dabbs, Jack E Feist, Hency Patel, Richard M Feist
{"title":"Increased Incidence of Asteroid Hyalosis in Bilaterial Macular Telangiectasia Type II Patients.","authors":"S Garrison Dabbs, Jack E Feist, Hency Patel, Richard M Feist","doi":"10.1097/IAE.0000000000004467","DOIUrl":"https://doi.org/10.1097/IAE.0000000000004467","url":null,"abstract":"<p><strong>Purpose: </strong>Investigate the relationship between Bilateral Macular Telangiectasia Type II (MacTel) and Asteroid Hyalosis (AH) and identify the factors that influence this correlation.</p><p><strong>Methods: </strong>A retrospective review utilizing the Retina Consultants of Alabama database from January 2016 to February 28, 2024 was conducted. The charts of 321 patients with retinal telangiectasias were assessed, and 143 were excluded. They were further partitioned into those with AH+MacTel (n=16) versus MacTel only (n=162). The incidence was determined and compared to population-based AH studies with similar patient demographics. Demographic and ocular data were collected and compared between the AH+MacTel and MacTel only groups.</p><p><strong>Results: </strong>AH was more prevalent in our MacTel cohort (9.88%) compared to Beaver Dam (1.20%, p<.001), Blue Mountains (1.01%, p<0.001), UCLA Autopsy (1.96%, p<.001), and Gutenberg Health studies (0.477%, p<0.001). An inverse link was found between AH+MacTel patients and posterior vitreous detachments (p<0.045 univariate, p<0.025 multivariate). AH+MacTel patients presented fewer ocular conditions (1.79±1.12) than MacTel only patients (2.31±1.11) and significantly lower OCT Central Subfield Thickness (224±43.0 μm) versus MacTel alone (249±49.6 μm; unadjusted mean difference: -25 μm, 95% CI: -45.3 to -4.76).</p><p><strong>Conclusion: </strong>There was a statistically significantly higher prevalence of patients with AH who also had a diagnosis of MacTel compared to the general population.</p>","PeriodicalId":54486,"journal":{"name":"Retina-The Journal of Retinal and Vitreous Diseases","volume":" ","pages":""},"PeriodicalIF":2.3,"publicationDate":"2025-03-10","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143665284","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Jay C Buckey, Drue Orwig, Kinjal Sethuraman, Owen O'Neill, Judith Rees, Janet Peacock
{"title":"Conclusions from Kalaw et al. paper are flawed and do a disservice to patients who present early after central retinal artery occlusion and may benefit from hyperbaric oxygen treatment.","authors":"Jay C Buckey, Drue Orwig, Kinjal Sethuraman, Owen O'Neill, Judith Rees, Janet Peacock","doi":"10.1097/IAE.0000000000004453","DOIUrl":"https://doi.org/10.1097/IAE.0000000000004453","url":null,"abstract":"","PeriodicalId":54486,"journal":{"name":"Retina-The Journal of Retinal and Vitreous Diseases","volume":" ","pages":""},"PeriodicalIF":2.3,"publicationDate":"2025-03-07","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143626821","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Giacomo Visioli, Giuseppe Maria Albanese, Luca Lucchino, Marta Armentano, Magda Gharbiya
{"title":"Letter to Editor: Addressing Inter-eye Correlation in Retinal Image Analysis for Patients with Bilateral Data.","authors":"Giacomo Visioli, Giuseppe Maria Albanese, Luca Lucchino, Marta Armentano, Magda Gharbiya","doi":"10.1097/IAE.0000000000004463","DOIUrl":"https://doi.org/10.1097/IAE.0000000000004463","url":null,"abstract":"","PeriodicalId":54486,"journal":{"name":"Retina-The Journal of Retinal and Vitreous Diseases","volume":" ","pages":""},"PeriodicalIF":2.3,"publicationDate":"2025-03-05","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143607134","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Tina Felfeli, Grace S Yin, Robert Shwarzman, Efrem D Mandelcorn
{"title":"The Cloverleaf Internal Limiting Membrane Flap Technique for Repair of Challenging Macular Holes.","authors":"Tina Felfeli, Grace S Yin, Robert Shwarzman, Efrem D Mandelcorn","doi":"10.1097/IAE.0000000000004446","DOIUrl":"https://doi.org/10.1097/IAE.0000000000004446","url":null,"abstract":"<p><strong>Purpose: </strong>This study introduces the Cloverleaf Internal Limiting Membrane (ILM) flap technique for managing challenging macular holes, aiming to enhance ILM flap placement and improve functional and anatomical outcomes.</p><p><strong>Methods: </strong>A retrospective review of cases undergoing the Cloverleaf ILM flap technique was conducted at a single center. This technique involves creating multiple ILM flaps in a cloverleaf configuration in order to enhance the stability and coverage of the macular hole. Clinical characteristics, surgical details, and outcomes were analyzed. Visual acuity measurements were converted to logMAR values.</p><p><strong>Results: </strong>The study included 29 eyes of 29 patients with a mean age of 65.3 years, and 58.6% females. Macular hole aperture and base sizes were 423.7 (± 264.9) µm and 1,017.5 (± 229.0) µm, respectively. Preoperatively, 62.1% of cases were phakic and 37.9% were pseudophakic. The median duration of symptoms was 90 (IQR: 60-300) days, with surgery performed approximately 34 (IQR: 28-69) days after presentation. Anatomical closure was achieved in 93.1% of cases. Patients had a mean 4.5 (± 4.4) Snellen lines of improvement in their visual acuity. The median duration of follow-up was 118 (IQR: 36-1,491) days.</p><p><strong>Conclusions: </strong>The Cloverleaf ILM flap technique may serve as a promising approach for challenging macular holes. By creating a cloverleaf configuration of quadratic ILM flaps folded over the MH, this technique enhances flap stability, potentially improving macular hole closure success.</p>","PeriodicalId":54486,"journal":{"name":"Retina-The Journal of Retinal and Vitreous Diseases","volume":" ","pages":""},"PeriodicalIF":2.3,"publicationDate":"2025-03-05","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143606732","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Response to letter to editor regarding LONG-TERM OUTCOMES OF SUTURELESS INTRASCLERAL INTRAOCULAR LENS FIXATION IN CHILDREN AND ADULTS: Single-Surgeon Case Series With and Without Haptic Flanging With Up to 11 Years of Follow-Up.","authors":"Spencer Moore, Mark Walsh","doi":"10.1097/IAE.0000000000004461","DOIUrl":"https://doi.org/10.1097/IAE.0000000000004461","url":null,"abstract":"","PeriodicalId":54486,"journal":{"name":"Retina-The Journal of Retinal and Vitreous Diseases","volume":" ","pages":""},"PeriodicalIF":2.3,"publicationDate":"2025-03-05","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143606058","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}