Retina-The Journal of Retinal and Vitreous Diseases最新文献_第5页

Investigation of hand tremor suppression by a customized passive surgical support robot during internal limiting membrane peeling. 研究定制的被动式手术支持机器人在内缘膜剥离过程中抑制手部震颤的效果。

IF 2.3 2区医学

Retina-The Journal of Retinal and Vitreous Diseases Pub Date : 2024-08-08 DOI: 10.1097/IAE.0000000000004226

Soichiro Yamamoto, Yuta Taniguchi, Yohei Kuroki, Hidenori Nagahama, Shin Tanaka, Kazuaki Kadonosono, Fumihito Arai, Hiroshi Enaida

{"title":"Investigation of hand tremor suppression by a customized passive surgical support robot during internal limiting membrane peeling.","authors":"Soichiro Yamamoto, Yuta Taniguchi, Yohei Kuroki, Hidenori Nagahama, Shin Tanaka, Kazuaki Kadonosono, Fumihito Arai, Hiroshi Enaida","doi":"10.1097/IAE.0000000000004226","DOIUrl":"https://doi.org/10.1097/IAE.0000000000004226","url":null,"abstract":"Purpose: To construct a quantitative evaluation system for hand tremor during internal limiting membrane (ILM) peeling and investigate changes in hand tremor attributable to the use of the customized passive surgical support robot.Methods: This analytical and experimental study developed a hand tremor evaluation system that synchronizes three elements: surgical microscope images, an artificial eye module with a force sensor to simulate ILM peeling, and microforceps with an inertial measurement unit. Two surgeons used this system to measure hand tremor during ILM peeling with and without the robot.Results: The horizontal, vertical, and combined vertical and horizontal components of hand tremor were 8.1 ± 6.1, 1.7 ± 1.8, and 8.5 ± 6.2 mG, respectively, in the no robot group. These components decreased to 7.2 ± 6.0, 1.5 ± 1.7, and 7.5 ± 6.1 mG, respectively, in the robot group. In particular, hand tremor was significantly suppressed by 11.9% for the horizontal component using the robot (p = 0.0006).Conclusion: The newly constructed system helps to quantitatively evaluate hand tremor during ILM peeling. The customized passive surgical support robot enables to decrease hand tremor during ILM peeling.","PeriodicalId":54486,"journal":{"name":"Retina-The Journal of Retinal and Vitreous Diseases","volume":null,"pages":null},"PeriodicalIF":2.3,"publicationDate":"2024-08-08","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141910123","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Smartphone Augmented En-Face Guided Epiretinal Membrane Peeling: A 3D Ngenuity Tool For Customized Treatment. 智能手机增强型面部引导视网膜外膜剥离术：用于定制治疗的 3D Ngenuity 工具。

IF 2.3 2区医学

Retina-The Journal of Retinal and Vitreous Diseases Pub Date : 2024-08-08 DOI: 10.1097/IAE.0000000000004239

Matteo Mario Carlà, Alessandra Scampoli, Lorenzo Governatori, Giulia Grieco, Tomaso Caporossi

{"title":"Smartphone Augmented En-Face Guided Epiretinal Membrane Peeling: A 3D Ngenuity Tool For Customized Treatment.","authors":"Matteo Mario Carlà, Alessandra Scampoli, Lorenzo Governatori, Giulia Grieco, Tomaso Caporossi","doi":"10.1097/IAE.0000000000004239","DOIUrl":"https://doi.org/10.1097/IAE.0000000000004239","url":null,"abstract":"Purpose: We aimed to introduce a novel visualization technique of en-face scans during epiretinal membrane (ERM) peeling, by using the in-built picture-in-picture (PIP) modality of the Alcon Ngenuity 3D System, connected to a smartphone.Methods: Prospective mono-centric interventional analysis on 20 patients undergoing vitrectomy and peeling for idiopathic ERMs. RTVue XR Avanti device was used perform a 6 × 6 mm optical coherence tomography angiography (OCTA). En-face image from a custom slab from 9 μm upon the internal limiting membrane (ILM) to 30 μm below the ILM was taken and 180° flipped. The smartphone was connected to the Alcon 3D Ngenuity display using an HDMI-to-USB cable and the picture-in-picture modality of the display was chosen in the software menu. ERM peeling was performed without dye stain starting from black linear structures on the en-face, indicating area of weaker adhesion to the ERM and could be used as cleavage point for membrane removal using vitreal forceps.Results: We reported successful peeling initiation and flap lift at the first forceps' grasp in all cases (100%). After ERM peeling, dual blue staining highlighted ILM remnants in 15 cases (75%) and peeling was completed. Total surgical time, including cable connections and projection to the display, was 41.6±9.2 minutes. Intraoperative total peeling time was 11.1±2.6 minutes. Central macular thickness significantly reduced 1 month after surgery (p=0.01).Conclusion: In summary, this is a cheap and easily reproducible surgical technique to optimize ERM management, offering an intraoperative guide for peeling initiation and minimizing un-necessary surgical maneuvers.","PeriodicalId":54486,"journal":{"name":"Retina-The Journal of Retinal and Vitreous Diseases","volume":null,"pages":null},"PeriodicalIF":2.3,"publicationDate":"2024-08-08","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141910127","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Sub retinal pigment epithelium hyporeflective spaces preceding large drusen collapse. 视网膜下色素上皮层反射不足，大块色素斑塌陷。

IF 2.3 2区医学

Retina-The Journal of Retinal and Vitreous Diseases Pub Date : 2024-08-06 DOI: 10.1097/IAE.0000000000004233

Elodie Bousquet, Neda Abraham, Rania Estawro, Simanta Khadka, Shilo Voichanski, Mostafa Mafi, Adrian Au, Ahmad Santina, SriniVas Sadda, David Sarraf

{"title":"Sub retinal pigment epithelium hyporeflective spaces preceding large drusen collapse.","authors":"Elodie Bousquet, Neda Abraham, Rania Estawro, Simanta Khadka, Shilo Voichanski, Mostafa Mafi, Adrian Au, Ahmad Santina, SriniVas Sadda, David Sarraf","doi":"10.1097/IAE.0000000000004233","DOIUrl":"https://doi.org/10.1097/IAE.0000000000004233","url":null,"abstract":"Purpose: To describe and study hyporeflective sub retinal pigment epithelium (RPE) spaces in large drusen and drusenoid pigment epithelial detachment prior to collapse.Method: Retrospective longitudinal study which enrolled patients with large and very large drusen due to intermediate age-related macular degeneration (AMD). The following optical coherence tomography (OCT) parameters were assessed: Drusen size (maximum width and height), OCT biomarkers of RPE atrophy, presence of intraretinal and subretinal fluid (IRF, SRF), acquired vitelliform lesion and sub RPE regions of hyporeflectivity within the PED compartment.Results: Of the 50 eyes from 41 patients (mean age of 77.1 ± 9 years, 78% women) with large and very large drusen, 16 eyes progressed to collapse. Eyes with sub RPE hyporeflective spaces (n=8 eyes, 50%) were associated with greater drusen width and height than eyes without sub RPE hyporeflective spaces. At the collapse visit, eyes with sub RPE hyporeflective spaces displayed poorer visual acuity and greater iRORA (incomplete RPE outer retinal atrophy) and cRORA (complete RORA) length than eyes without sub RPE hyporeflective spaces (p=0.004 and p=0.04, respectively).Conclusion: Sub RPE hyporeflective spaces are a novel OCT finding of large and very large drusen that collapse to atrophy. Progressive RPE dysfunction and failure may lead to reduced drusenoid material formation and progressive degenerative hydration of the large drusen prior to collapse, but this awaits confirmation with histopathological analysis.","PeriodicalId":54486,"journal":{"name":"Retina-The Journal of Retinal and Vitreous Diseases","volume":null,"pages":null},"PeriodicalIF":2.3,"publicationDate":"2024-08-06","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141908329","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Periocular Acupuncture Leading to Retinal Tear and Successful Repairment. 眼周针灸导致视网膜撕裂并成功修复。

IF 2.3 2区医学

Retina-The Journal of Retinal and Vitreous Diseases Pub Date : 2024-08-06 DOI: 10.1097/IAE.0000000000004234

Yi-Chen Huang, Nan-Kai Wang, Pei-Kang Liu

引用次数: 0

Pseudo Retinal Vasculitis in a Preterm Baby. 早产儿假性视网膜血管炎

IF 2.3 2区医学

Retina-The Journal of Retinal and Vitreous Diseases Pub Date : 2024-08-06 DOI: 10.1097/IAE.0000000000004232

Kushal U Agrawal, Abhishek Das, Prema Subramanyam, Parag K Shah, Venkatapathy Narendran

引用次数: 0

Assessment of the effects of two commonly used mydriatics on the macular and peripapillary microvascular systems of healthy children: An Optical Coherence Tomography Angiography Study. 评估两种常用催泪剂对健康儿童黄斑和毛细血管系统的影响：光学相干断层扫描血管造影研究。

IF 2.3 2区医学

Retina-The Journal of Retinal and Vitreous Diseases Pub Date : 2024-08-05 DOI: 10.1097/IAE.0000000000004230

Sevim Ayca Seyyar, Gizem Gürbostan Soysal, Burçak Balyemez

{"title":"Assessment of the effects of two commonly used mydriatics on the macular and peripapillary microvascular systems of healthy children: An Optical Coherence Tomography Angiography Study.","authors":"Sevim Ayca Seyyar, Gizem Gürbostan Soysal, Burçak Balyemez","doi":"10.1097/IAE.0000000000004230","DOIUrl":"https://doi.org/10.1097/IAE.0000000000004230","url":null,"abstract":"Purpose: To evaluate the effects of pupil dilation caused by topical applications of 2.5% phenylephrine and 0.5% tropicamide on retinal microvascularization using optical coherence tomography angiography (OCTA).Methods: Healthy children were included in this prospective observational study. Baseline OCTA measurements were taken for all children before dilatation. Then they were randomly divided into two groups, the tropicamide group given 0.5% tropicamide solution and the phenylephrine group given 2.5% phenylephrine solution. After dilation OCTA images were taken for the second time from all children.Results: The effect of dilation using two different mydriatic agents caused a decrease in mean radial peripapillary capillary density (RPC-VD) and superior RPC-VD (p=0.008 and p=0.001). Remarkably, this reduction due to dilatation was also determined to be caused by the combined effect of both mydriatic agents (p=0.016 and p=0.013). Although phenylephrine showed a slightly greater decrease than tropicamide, the effects of the two mydriatic drugs were not superior to each other (p=0.166 and p=0.167).Conclusion: Dilation with 2.5% phenylephrine or 0.5% tropicamide significantly decreased mean RPC-VD and superior RPC-VD. Although there was no statistically significant difference between the two mydriatic agents, phenylephrine caused a greater reduction than tropicamide. This effect of dilation and phenylephrine on VD should be considered in studies using OCTA and focusing on peripapillary areas.","PeriodicalId":54486,"journal":{"name":"Retina-The Journal of Retinal and Vitreous Diseases","volume":null,"pages":null},"PeriodicalIF":2.3,"publicationDate":"2024-08-05","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141898889","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Dynamic Viral Load Monitoring and Metagenomic Sequencing in Acute Retinal Necrosis Caused by Varicella-Zoster Virus. 水痘-带状疱疹病毒引起的急性视网膜坏死中的动态病毒载量监测和元基因组测序

IF 2.3 2区医学

Retina-The Journal of Retinal and Vitreous Diseases Pub Date : 2024-08-05 DOI: 10.1097/IAE.0000000000004214

Junxiang Gu, Boya Lei, Zhujian Wang, Ting Zhang, Tingting Jiang, Peijun Zhang, Wenwen Chen, Yanqiong Zhang, Rui Jiang, Gezhi Xu, Qing Chang, Min Zhou

{"title":"Dynamic Viral Load Monitoring and Metagenomic Sequencing in Acute Retinal Necrosis Caused by Varicella-Zoster Virus.","authors":"Junxiang Gu, Boya Lei, Zhujian Wang, Ting Zhang, Tingting Jiang, Peijun Zhang, Wenwen Chen, Yanqiong Zhang, Rui Jiang, Gezhi Xu, Qing Chang, Min Zhou","doi":"10.1097/IAE.0000000000004214","DOIUrl":"https://doi.org/10.1097/IAE.0000000000004214","url":null,"abstract":"Purpose: To analyze the trend of intraocular viral load after antiviral treatment in patients with varicella-zoster virus (VZV) induced acute retinal necrosis (ARN), and to explore the effect of viral genotypes on clinical manifestations.Methods: In this case series, viral load was detected using polymerase chain reaction from aqueous humor during treatment; viral load curves were fitted, and the time required to reach the inflection point between plateau phase and logarithmic reduction phase (Tinflection) was estimated. Variations in viral genomes were detected by metagenomic sequencing.Results: Twenty eyes of 20 patients were included. The median (interquartile range) initial viral load was 5.9×107 (1.1×107-1.1×108) copies/mL. The average duration of retinitis was 5±3 weeks. The average Tinflection was 4.2±1.6 days. Tinflection was correlated with the duration of retinitis (P=0.025). Patients with VZVs carrying the p.S715* variation in ribonucleotide reductase (RNR) subunit 1 gene had lower initial viral loads (median 1.3×107 copies/ml) than those without (median 1.1×108 copies/ml; adjusted P=0.030).Conclusions: The inflection of viral load curve is helpful to estimate the length of plateau phase and the duration of retinitis during antiviral treatment in ARN patients. Loss-of-function variation in RNR gene might be correlated with lower virulence of VZV.","PeriodicalId":54486,"journal":{"name":"Retina-The Journal of Retinal and Vitreous Diseases","volume":null,"pages":null},"PeriodicalIF":2.3,"publicationDate":"2024-08-05","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141983978","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Intraocular Pressure and Safety of Vitrectomy with Vitreous Gas Replacement using Low-concentration Nitrous Oxide Gas Anesthesia. 使用低浓度氧化亚氮气体麻醉进行玻璃体气体置换玻璃体切除术的眼压和安全性

IF 2.3 2区医学

Retina-The Journal of Retinal and Vitreous Diseases Pub Date : 2024-08-02 DOI: 10.1097/IAE.0000000000004225

Santaro Noguchi, Shunsuke Nakakura, Asuka Noguchi, Hitoshi Tabuchi

{"title":"Intraocular Pressure and Safety of Vitrectomy with Vitreous Gas Replacement using Low-concentration Nitrous Oxide Gas Anesthesia.","authors":"Santaro Noguchi, Shunsuke Nakakura, Asuka Noguchi, Hitoshi Tabuchi","doi":"10.1097/IAE.0000000000004225","DOIUrl":"https://doi.org/10.1097/IAE.0000000000004225","url":null,"abstract":"Purpose: This study aims to evaluate the efficacy and safety of vitrectomy with vitreous gas replacement using low-concentration nitrous oxide (N2O) gas anesthesia, focusing on intraocular pressure (IOP) changes, pain, anxiety, and safety outcomes.Methods: This retrospective study analyzed 133 patients undergoing fluid-air exchange without use of such as SF6 or C3F8, at Saneikai Tsukazaki Hospital, Japan, from April 2019 to March 2022. Participants were divided into two groups: those receiving low-concentration nitrous oxide gas anesthesia (N2O group) and those receiving local anesthesia with room air inhalation (Air group). IOP, pain, anxiety levels, and intraoperative complications were assessed.Results: No significant differences were found in IOP changes postoperatively between the N2O and Air groups. The N2O group reported significantly lower pain scores and had lower intraoperative systolic blood pressure and heart rate changes compared with the Air group. No significant intraoperative or postoperative complications were observed in either group.Conclusion: Vitrectomy with fluid-air exchange using low-concentration nitrous oxide gas anesthesia is safe, does not increase IOP, and may offer benefits in reducing intraoperative pain and stabilizing vital signs compared with traditional local anesthesia methods. This approach could be considered a viable option for vitreous surgery requiring fluid-air exchange.","PeriodicalId":54486,"journal":{"name":"Retina-The Journal of Retinal and Vitreous Diseases","volume":null,"pages":null},"PeriodicalIF":2.3,"publicationDate":"2024-08-02","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141879812","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Aspergillus niger associated retinitis - a dark diagnostic dilemma. 与黑曲霉相关的视网膜炎--黑暗中的诊断难题。

IF 2.3 2区医学

Retina-The Journal of Retinal and Vitreous Diseases Pub Date : 2024-08-01 DOI: 10.1097/IAE.0000000000004228

Kasturi Chavan, Vishal Jadhav, Himansu Sekhar Behera, Anup Kelgaonkar, Soumyava Basu, Avinash Pathengay

引用次数: 0

Progression of Peripapillary and Macular Chorioretinal Atrophy in Multifocal Choroiditis Is Associated with Periatrophic Inflammatory Plumes. 多灶性脉络膜炎的毛细血管周围和黄斑脉络膜视网膜萎缩的进展与周围炎性羽状细胞有关。

IF 2.3 2区医学

Retina-The Journal of Retinal and Vitreous Diseases Pub Date : 2024-08-01 DOI: 10.1097/IAE.0000000000004227

Jeannette Ossewaarde-van Norel, Richard F Spaide

{"title":"Progression of Peripapillary and Macular Chorioretinal Atrophy in Multifocal Choroiditis Is Associated with Periatrophic Inflammatory Plumes.","authors":"Jeannette Ossewaarde-van Norel, Richard F Spaide","doi":"10.1097/IAE.0000000000004227","DOIUrl":"https://doi.org/10.1097/IAE.0000000000004227","url":null,"abstract":"Purpose: To investigate peripapillary atrophy and macular chorioretinal scars in eyes affected by multifocal choroiditis and panuveitis (MCP).Methods: This retrospective cohort study reviewed the medical records, fundus photographs, and SD-OCT scans of 31 eyes from 19 patients.Results: Patients had a mean age of 45 years (range 24-69 years). The average follow-up duration was 7 years (range 2.5-14.5 years), with 14 patients undergoing immunosuppressive treatment. In the group of 31 eyes, 20 showed peripapillary plumes of ill-defined hyperreflectivity at the termination border of the retinal pigment epithelium (RPE). These plumes, extending from bare Bruch's membrane to the outer nuclear layer, sometimes undermined the adjacent RPE. They responded to corticosteroid treatment and resembled the material under the RPE in acute lesions. Among 20 eyes with these peripapillary inflammatory lesions, 16 (80%) experienced increased atrophy, in contrast to none in the eyes without these lesions (P<0.001). Similar patterns were observed at the edges of macular chorioretinal atrophy. This observation occurred in patients using immunosuppressive medication who were otherwise thought to be under adequate control.Conclusion: In MCP patients, previously unrecognized plumes of smoldering inflammatory activity at the borders of chorioretinal atrophy appears to be linked to atrophy expansion. The recognition of this phenomenon may require a reappraisal of treatment of multifocal choroidopathies to help mitigate expansion of atrophy in these eyes.","PeriodicalId":54486,"journal":{"name":"Retina-The Journal of Retinal and Vitreous Diseases","volume":null,"pages":null},"PeriodicalIF":2.3,"publicationDate":"2024-08-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141876685","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0