Samar A. Salim, Tasneem Abed, Esraa B. Abdelazim, Noura G. Eissa, Mahmoud Elsabahy, Elbadawy A. Kamoun
{"title":"Exploring the Therapeutic Potential of Plant Extract-Loaded Polymeric Nanoparticles for Advanced Wound Healing: A Comprehensive Review","authors":"Samar A. Salim, Tasneem Abed, Esraa B. Abdelazim, Noura G. Eissa, Mahmoud Elsabahy, Elbadawy A. Kamoun","doi":"10.1007/s13369-025-10247-1","DOIUrl":"10.1007/s13369-025-10247-1","url":null,"abstract":"<div><p>Wound healing is a complex biological process that can be hindered by factors such as infection, poor circulation, and chronic conditions. Traditional wound treatments often fall short in providing optimal healing environments and infection control. This review explores the innovative use of plant extract-loaded polymeric nanoparticles (PNPs) in wound care, highlighting their potential to revolutionize wound management. PNPs offer controlled and sustained delivery of therapeutic agents, enhanced antimicrobial properties, and improved wound-healing outcomes. Various types of PNPs, including nanospheres, nanocapsules, dendrimers, micelles, and hydrogels, are discussed for their unique properties and applications. The synthesis, characterization, and in vitro and in vivo evaluations of these nanoparticles are highlighted, emphasizing their efficacy in promoting faster re-epithelialization, angiogenesis, and collagen deposition. Additionally, the therapeutic potential of plant extracts, such as <i>Syzygium cumini</i>, <i>Tamarindus indica</i>, <i>Calendula officinalis</i>, Chamomile oil, and Neem, when encapsulated in nanoparticles, is evaluated for their wound-healing properties. Future research directions include optimizing nanoparticle formulations and conducting clinical trials to validate their safety and effectiveness. This review underscores the promise of plant extract-loaded PNPs in setting new standards in wound care, potentially improving patient outcomes and reducing healthcare costs associated with chronic wounds.</p><h3>Graphical Abstract</h3><div><figure><div><div><picture><source><img></source></picture></div></div></figure></div></div>","PeriodicalId":54354,"journal":{"name":"Arabian Journal for Science and Engineering","volume":"50 18","pages":"14351 - 14369"},"PeriodicalIF":2.9,"publicationDate":"2025-05-13","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145037088","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"综合性期刊","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"A Large Active Inductor Emulator for Biomedical Applications","authors":"Ahmed Reda Mohamed, Muneer A. Al Absi","doi":"10.1007/s13369-025-10204-y","DOIUrl":"10.1007/s13369-025-10204-y","url":null,"abstract":"<div><p>This paper presents a fully integrated and tunable grounded active inductor (GAI) with a high equivalent inductance suitable for biomedical applications such as photoplethysmography (PPG) sensors. The proposed GAI is constructed from a modified <span>(2^{nd})</span> generation current conveyor (M-CCII), a grounded capacitor multiplier (CM), a transconductance amplifier (OTA), and a single resistor. The proposed GAI’s functionality is verified using Cadence in 180-nm TSMC CMOS technology. The simulation results indicate that an equivalent inductance of up to 10 H can be achieved with a relative maximum error of 5 % over an operating frequency range of up to 750 Hz. The proposed GAI occupies a silicon area of 0.0364 <span>(hbox {mm}^2)</span> and consumes a power of 34.2 <span>(mu )</span>W when powered from a 1.8 V supply voltage. The proposed design is exploited in designing a bandpass filter with a high-pass corner frequency of 200 mHz and a low-pass corner frequency of 6.4 Hz to filter out 50–60 Hz power lines and biosignals interferences. Monte Carlo statistical analysis and process–voltage–temperature variations have been used to guarantee prototype operation during prospective manufacturing. Furthermore, the comparative table and the figure of merit (FOM) demonstrate that this work is superior to prior arts.</p></div>","PeriodicalId":54354,"journal":{"name":"Arabian Journal for Science and Engineering","volume":"50 14","pages":"10881 - 10901"},"PeriodicalIF":2.9,"publicationDate":"2025-05-11","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145164065","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"综合性期刊","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Dandi Alvayed, Saad Alafnan, Murtada Saleh Aljawad, Abduljamiu O. Amao
{"title":"Integrative Analysis of Mechanical Heterogeneity in Organic-Rich Shales: Bridging Nano- and Macroscale Properties for an Enhanced Geomechanical Understanding","authors":"Dandi Alvayed, Saad Alafnan, Murtada Saleh Aljawad, Abduljamiu O. Amao","doi":"10.1007/s13369-025-10180-3","DOIUrl":"10.1007/s13369-025-10180-3","url":null,"abstract":"<div><p>Understanding the mechanical properties of shale is critical for hydraulic fracturing and rock physics modeling. However, the complex and heterogeneous nature of the shale matrix poses significant challenges for analyzing its behavior across various scales. This study introduces a method for investigating the mechanical heterogeneity of samples from Eagle Ford shales using a combination of nano-indentation and macroscopic mechanical testing. The results reveal a dual-peak distribution in the nanoscale measurements for Young's modulus and hardness properties, indicating a comparable frequency of soft and hard constituents, validated by SEM mapping. Young's modulus and hardness values exhibit significant mechanical heterogeneity at the nanoscale level, varying between 7–85 GPa and 0.3–4.9 GPa, respectively. Meanwhile, macroscale yield displays a normal distribution for Young's modulus values ranging from 25 to 60 GPa, representing the overall behavior of mechanical properties. The properties at different locations within the core plug at the nanoscale were statistically correlated with macroscopic properties. The study revealed that the macroscopic behavior is influenced by both soft and hard components in proportions corresponding to their frequencies. The reported outcomes provide valuable insights for improved modeling and the design of stimulation processes to exploit shale resources further.</p></div>","PeriodicalId":54354,"journal":{"name":"Arabian Journal for Science and Engineering","volume":"50 13","pages":"10525 - 10539"},"PeriodicalIF":2.9,"publicationDate":"2025-04-27","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145170312","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"综合性期刊","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"A Simplified and Robust Design Procedure for Humidification-Dehumidification Systems with Air Extractions","authors":"M. A. M. Ahmed, Syed M. Zubair","doi":"10.1007/s13369-025-10123-y","DOIUrl":"10.1007/s13369-025-10123-y","url":null,"abstract":"<div><p>This study presents a streamlined methodology for designing thermally optimized humidification-dehumidification systems that operate with zero, one, or two air extractions. The developed method is a direct model that integrates system sizing with performance predictions, emphasizing the correlation between key performance indicators and design parameters. The model requires inputs including saline-water salinity (0–100 ppt), minimum and maximum temperatures (20–40 °C and 60–80 °C), enthalpy pinch (1 kJ/kg to the critical limit), and air extraction count (0–2). It underpins extensive datasets that derive design correlations for evaluating metrics such as gain-output ratio, mass flow rate ratio, recovery ratio, energy efficiency, and critical enthalpy pinch. Additionally, essential elements of design, like the humidifier's volume and the dehumidifier's surface area, are carefully evaluated. Offering broad operational flexibility and achieving accuracy within 5% when validated against literature, this model enhances the applicability of humidification-dehumidification systems in real-world settings. This approach provides a practical and robust predictive tool, offering significant utility to engineers and researchers in designing energy-efficient and adaptable humidification-dehumidification desalination systems across diverse conditions.</p></div>","PeriodicalId":54354,"journal":{"name":"Arabian Journal for Science and Engineering","volume":"50 17","pages":"14301 - 14332"},"PeriodicalIF":2.9,"publicationDate":"2025-04-24","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145128600","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"综合性期刊","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Improvement of the Approximate Method for Determining the Average Vertical Stress Increase Below the Rectangular Foundation Using Differential Evolution Algorithm","authors":"Ugur Dagdeviren","doi":"10.1007/s13369-025-10196-9","DOIUrl":"10.1007/s13369-025-10196-9","url":null,"abstract":"<div><p>External loads transferred from the structure's foundations to the soil induce stress increases in the soil stratum. Since stress increases within the soil mass vary with depth and across the plane at a given depth, approaches that estimate the average stress increase under foundations can be advantageous for effective foundation design. This study aims to develop optimization-based approximate methods for calculating average vertical stress increases with higher accuracy than the conventional 2V:1H method for rectangular foundations with different L/B ratios. For this purpose, vertical stress increases within the foundation projection at 120 different depths for 12 different L/B ratios were numerically calculated using Boussinesq’s stress expressions. The model parameters of the proposed approximate models, such as expansion slopes (k or k<sub>1</sub>, k<sub>2</sub>) and normalized critical depth (z<sub>cr</sub>/B), for each L/B ratio were optimized using the differential evolution algorithm. The proposed three-parameter approximate method achieved the highest accuracy, reducing the RMSE values by an average of 53% compared to the conventional method, while the one-parameter model reduced the RMSE by 9%. The maximum absolute errors in the three-parameter model remained between 0.0217 and 0.0283, with R<sup>2</sup> values greater than 0.9972. Building upon and improving the conventional method, this study presents a practical and novel three-parameter method that provides a more reliable and accurate estimation of the average vertical stress increase under flexible rectangular foundations, significantly reducing errors. This study contributes to geotechnical engineering by improving the accuracy of stress increase prediction models, potentially leading to more economical and safer foundation designs.</p></div>","PeriodicalId":54354,"journal":{"name":"Arabian Journal for Science and Engineering","volume":"50 20","pages":"17133 - 17152"},"PeriodicalIF":2.9,"publicationDate":"2025-04-23","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://link.springer.com/content/pdf/10.1007/s13369-025-10196-9.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145236819","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"综合性期刊","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Effect of Metal Oxide Nanoparticles on the Properties of Nanocomposite Gels for Water Shutoff Applications: A Review","authors":"Tarek Ganat, Saeed Khezerloo-ye, Muhammad Alrumah, Alireza Kazemi, Hamoud Al-Hadrami, Usman Taura","doi":"10.1007/s13369-025-10189-8","DOIUrl":"10.1007/s13369-025-10189-8","url":null,"abstract":"<div><p>This review comprehensively examines the role of metal oxide nanoparticles in enhancing the properties of nanocomposite polymer gels for water shutoff applications in the oil and gas industry. The study highlights the critical importance of optimizing gel formulations to address challenges such as water production, which significantly impacts oil recovery efficiency and operational costs. The review is structured to first discuss the fundamental components of polymer gels, including polymers, crosslinkers, and additives, and their roles in gel synthesis. It then delves into the evaluation methods for key gel properties, such as gelation time, gel strength, viscosity, thermal stability, and syneresis resistance. A significant focus is placed on the impact of metal oxide nanoparticles, such as SiO<sub>2</sub>, Al<sub>2</sub>O<sub>3</sub>, Fe<sub>2</sub>O<sub>3</sub>, and Cr<sub>2</sub>O<sub>3</sub>, on these properties. The review demonstrates that nanoparticles enhance gel strength, thermal stability, and resistance to syneresis without significantly altering gelation time, making them ideal for harsh subsurface conditions. Furthermore, the review explores the morphological and textural characteristics of gels using SEM imaging, emphasizing the importance of nanoparticle dispersion and concentration. The findings underscore the potential of nanocomposite gels to improve water shutoff efficiency, reduce permeability, and enhance oil recovery. By integrating recent research and experimental data, this review provides a detailed roadmap for optimizing nanocomposite gel formulations, offering valuable insights for researchers and industry professionals aiming to develop advanced materials for water shutoff applications.</p></div>","PeriodicalId":54354,"journal":{"name":"Arabian Journal for Science and Engineering","volume":"50 13","pages":"9771 - 9789"},"PeriodicalIF":2.9,"publicationDate":"2025-04-16","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145166044","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"综合性期刊","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Numerical Investigation of Heat and Mass Transfer Enhancement in Ternary Nano-Casson Fluid in the Presence of Cattaneo−Christov Theory with Hall and Ion Slip Effects","authors":"Muhammad Abid, Tayyaba Akhtar, Madiha Bibi","doi":"10.1007/s13369-025-10058-4","DOIUrl":"10.1007/s13369-025-10058-4","url":null,"abstract":"<div><p>This study presents a groundbreaking investigation into the three-dimensional flow of a ternary nanofluid over a stretching surface, integrating advanced models for non-Newtonian fluids, electromagnetic effects, and non-Fourier heat conduction. The combination of <span>(left( Al_{2}O_{3},CuO,TiO_{2}right) )</span> nanoparticles in a water-based Casson fluid, incorporating Hall and ion slip effects within a Cattaneo–Christov double-diffusion framework. The inclusion of nanoparticles significantly enhances heat transfer rates, Hall and ion slip parameters exhibit a pronounced effect on velocity profiles and Cattaneo–Christov model reveals notable deviations in temperature profiles. Employing an enhanced finite-element method, we provide comprehensive numerical solutions, validated against existing literature for special cases. Our results offer new insights into complex nanofluid systems, with direct applications in advanced cooling technologies, biomedical engineering, and next-generation heat exchangers.</p></div>","PeriodicalId":54354,"journal":{"name":"Arabian Journal for Science and Engineering","volume":"50 13","pages":"10245 - 10258"},"PeriodicalIF":2.9,"publicationDate":"2025-04-16","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145165237","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"综合性期刊","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Abdulrahman K. Aluraik, Mohammed Ali Al-Ameer, M. Elmuzafar Ahmed, Madhar Sahib Azad, Mohamed Abdalla, Mustafa Al Ramadan
{"title":"Does Perforated Completion Strategy Aid Water-Based Chemical Flooding to Mitigate Gravity Segregation?","authors":"Abdulrahman K. Aluraik, Mohammed Ali Al-Ameer, M. Elmuzafar Ahmed, Madhar Sahib Azad, Mohamed Abdalla, Mustafa Al Ramadan","doi":"10.1007/s13369-025-10187-w","DOIUrl":"10.1007/s13369-025-10187-w","url":null,"abstract":"<div><p>Chemical flooding is a widely used enhanced oil recovery (EOR) method that involves injecting water-based chemicals into the reservoir. These chemicals are typically denser than oil, leading to gravity segregation, wherein the denser fluid underruns the oil, reducing sweep efficiency and overall recovery. This study evaluates the effectiveness of perforated completion versus open-hole completion in mitigating gravity segregation during surfactant and polymer flooding, two common chemical flooding techniques. While surfactant and polymer solutions have similar densities (1 g/cc), they differ significantly in viscosity and interfacial tension (IFT). Simulations using commercial software were conducted for a quarter of a five-spot pattern with varying reservoir properties, including anisotropy (0.1–0.75), oil viscosity (10–100 cP), and thickness (50–200 ft). Flooding durations of 5 months and 5 years were examined. Recovery and profitability served as metrics for evaluating completion strategies. Results indicate that polymer flooding, due to its higher viscosity, mitigates gravity segregation effectively with both open-hole and perforated completions, rendering the additional cost of perforation ($80,000 per operation) unjustified. Conversely, surfactant flooding benefits significantly from perforated completion under specific conditions. For short flooding periods, perforated completions increased recovery by 1,500–2,000 barrels in reservoirs with lower anisotropy (0.1), higher oil viscosity (100 cP), and greater thickness. This improvement is attributed to the selective slowing of surfactant movement, which enhances vertical sweep efficiency. Economically, perforated completions generate additional revenue ranging from $20,000 to $225,000, justifying their use in short-term surfactant floods but not in polymer floods if the objective is to prevent gravity segregation. The findings suggest that perforated completions are particularly advantageous for flooding with low-viscosity injection fluids (e.g., water or surfactant) in reservoirs characterized by high oil viscosity, significant thickness, and moderate anisotropy. In summary, while polymer floods mitigate gravity segregation well regardless of completion strategy for the studied conditions, surfactant flooding benefits from perforated completions in specific scenarios, emphasizing the importance of tailoring EOR strategies to reservoir characteristics and project duration.</p></div>","PeriodicalId":54354,"journal":{"name":"Arabian Journal for Science and Engineering","volume":"50 13","pages":"10507 - 10523"},"PeriodicalIF":2.9,"publicationDate":"2025-04-16","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145166045","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"综合性期刊","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Study on the Mechanical Properties of Fiber Reinforced Concrete Composite to Cryogenic Temperatures","authors":"Yang Li, Yongqi Chen, Junhui He, Wei Hu, Yifan Wang, Ruolan Peng, Xiaofang Peng","doi":"10.1007/s13369-025-10077-1","DOIUrl":"10.1007/s13369-025-10077-1","url":null,"abstract":"<div><p>This paper investigates the mechanical properties of steel-polypropylene hybrid fiber-reinforced concrete (HFRC) at low temperatures, including 20 ℃, − 40 ℃, − 80 ℃, − 120 ℃, and − 165 ℃. The compressive strength, tensile strength, flexural strength, and stress-strain relationships of the material under these conditions were tested and analyzed. The results indicate that the compressive strength, tensile strength, peak stress, elastic modulus, and flexural strength of HFRC are improved under low temperatures, while the peak strain decreases. Additionally, the mechanical properties and flexural toughness of HFRC are better than normal concrete (NC). Among specimens with different fiber compositions, the HFRC specimen containing 0.5% steel fibers (SF) and 0.1% polypropylene fibers (PF) exhibited optimal mechanical properties. Finally, the test results were used to develop a calculation model for determining the compressive, tensile, and flexural strengths of HFRC. By modifying the parameters of existing stress-strain models, a stress-strain model for HFRC under low-temperature conditions was established.</p></div>","PeriodicalId":54354,"journal":{"name":"Arabian Journal for Science and Engineering","volume":"50 20","pages":"17109 - 17132"},"PeriodicalIF":2.9,"publicationDate":"2025-04-13","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145236912","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"综合性期刊","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Eugene N. Ngouangna, Iskandar B. Dzulkarnain, Mohd Zaidi Jaafar, Jeffrey O. Oseh, Funsho A. Afolabi, Faruk Yakasai, Afeez O. Gbadamosi, Peter Ikechukwu Nwaichi, Augustine Agi
{"title":"Nanoparticles Transport in Porous Media During EOR Operations: A Wide-Ranging Review of Mechanisms, Mathematical Models, Influencing Parameters, Challenges, and Prospects","authors":"Eugene N. Ngouangna, Iskandar B. Dzulkarnain, Mohd Zaidi Jaafar, Jeffrey O. Oseh, Funsho A. Afolabi, Faruk Yakasai, Afeez O. Gbadamosi, Peter Ikechukwu Nwaichi, Augustine Agi","doi":"10.1007/s13369-025-10050-y","DOIUrl":"10.1007/s13369-025-10050-y","url":null,"abstract":"<div><p>Nanofluids’ stability and promise have made nanoparticles (NPs) popular in enhanced oil recovery (EOR) projects. Chemical-EOR solutions composed of polymers and surfactants are extremely effective in oil recovery; nevertheless, they deteriorate and lose efficacy at rising temperatures and salinities, rendering them less effective. Nanofluids may endure these reservoir conditions due to their exceptional properties. Fluids and rocks’ characteristics and interactions in porous media have changed due to NP surface features, promoting EOR. NP behaviour and roles in porous media must be understood before using NPs in subterranean projects. This work aims to improve understanding of NPs in porous medium to help construct NPs-EOR projects. In response to subsurface EOR developments, this paper discusses NP behaviour, mathematical models, and transport mechanisms, influencing factors, challenges encountered and EOR NP application prospects. The work equally addresses NP-based EOR issues, emphasizing the need for more research. The review found that NPs reduce interfacial tension and slipperiness to improve compatibility between incompatible fluids. Through nanofluid movement in porous media and EOR processes, injection rate, NP diameter, chemical composition, surface properties, and nanofluid concentration all affect their transport and oil recovery.</p></div>","PeriodicalId":54354,"journal":{"name":"Arabian Journal for Science and Engineering","volume":"50 13","pages":"9737 - 9769"},"PeriodicalIF":2.9,"publicationDate":"2025-04-11","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145163675","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"综合性期刊","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}