Topics in Current Chemistry最新文献

{"title":"O-Benzoylhydroxylamines: A Versatile Electrophilic Aminating Reagent for Transition Metal-Catalyzed C–N Bond-Forming Reactions","authors":"Sachin Balaso Mohite,&nbsp;Milan Bera,&nbsp;Vishal Kumar,&nbsp;Rajshekhar Karpoormath,&nbsp;Shaik Baji Baba,&nbsp;Arjun S. Kumbhar","doi":"10.1007/s41061-022-00414-5","DOIUrl":"10.1007/s41061-022-00414-5","url":null,"abstract":"<div><p>Owing to the prevalence of nitrogen-containing compounds in natural products and important pharmaceutical agents, chemists, have actively searched for the development of efficient and selective methodologies allowing for the facile construction of carbon–nitrogen bonds. Over the last decade, transition metal-catalyzed C–N bond construction via electrophilic amination reaction has emerged as an attractive approach for the synthesis of various organic molecules and pharmaceuticals. Particularly, <i>O</i>-benzoylhydroxylamines as an electrophilic aminating agent have proven to be the best and most widely used in both academic and industrial research. In this review, we highlight the key contributions to the recent transition metal-catalyzed C–N bond formation reactions using <i>O</i>-benzoylhydroxylamines as an aminating agent and their relevant mechanistic insights.</p><h3>Graphical Abstract</h3>\u0000 <figure><div><div><div><picture><source><img></source></picture></div></div></div></figure>\u0000 </div>","PeriodicalId":54344,"journal":{"name":"Topics in Current Chemistry","volume":"381 1","pages":""},"PeriodicalIF":8.6,"publicationDate":"2022-12-18","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"5006522","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"化学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Water-Soluble Carbon Monoxide-Releasing Molecules (CORMs)","authors":"Huma Khan,&nbsp;Muhammad Faizan,&nbsp;Salamat Ullah Khan Niazi,&nbsp; Madiha,&nbsp;Niaz Muhammad,&nbsp;Weiqiang Zhang","doi":"10.1007/s41061-022-00413-6","DOIUrl":"10.1007/s41061-022-00413-6","url":null,"abstract":"<div><p>Carbon monoxide-releasing molecules (CORMs) are promising candidates for producing carbon monoxide in the mammalian body for therapeutic purposes. At higher concentrations, CO has a harmful effect on the mammalian organism. However, lower doses at a controlled rate can provide cellular signaling for mandatory pharmacokinetic and pathological activities. To date, exploring the therapeutic implications of CO dose as a prodrug has attracted much attention due to its therapeutic significance. There are two different methods of CO insertion, i.e., indirect and direct exogenous insertion. Indirect exogenous insertion of CO suggests an advantage of reduced toxicity over direct exogenous insertion. For indirect exogenous insertion, researchers are facing the issue of tissue selectivity. To solve this issue, developers have considered the newly produced CORMs. Herein, metal carbonyl complexes (MCCs) are covalently linked with CO molecules to produce different CORMs such as CORM-1, CORM-2, and CORM-3, etc. All these CORMs required exogenous CO insertion to achieve the therapeutic targets at the optimized rate under peculiar conditions or/and triggering. Meanwhile, the metal residue was generated from i-CORMs, which can propagate toxicity. Herein, we explain CO administration, water-soluble CORMs, tissue accumulation, and cytotoxicity of depleted CORMs and the kinetic profile of CO release.</p><h3>Graphical Abstract</h3>\u0000 <figure><div><div><div><picture><source><img></source></picture></div></div></div></figure>\u0000 </div>","PeriodicalId":54344,"journal":{"name":"Topics in Current Chemistry","volume":"381 1","pages":""},"PeriodicalIF":8.6,"publicationDate":"2022-12-14","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"4569021","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"化学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Greener Syntheses of Coumarin Derivatives Using Magnetic Nanocatalysts: Recent Advances","authors":"Shohreh Zeinali,&nbsp;Leila Zare Fekri,&nbsp;Mohammad Nikpassand,&nbsp;Rajender S. Varma","doi":"10.1007/s41061-022-00407-4","DOIUrl":"10.1007/s41061-022-00407-4","url":null,"abstract":"<div><p>Coumarins (2<i>H</i>-1-benzopyran-2-ones) are an important group of biological heterocyclic compounds present in various parts of many plant species, encompassing an array of biological and pharmaceutical activities. In view of the importance of coumarins in heterocyclic chemistry and biological sciences and recent advances in the design of magnetic nanocatalysts, we present herein recent developments pertaining to their synthesis exclusively using magnetic nanoparticles, which can be retrieved easily and thus conform to the tenets of greener synthesis. The preparation of various types of coumarins such as Pechmann-based coumarins, bis coumarins, pyranocoumarins, and coumarin derivatives bearing amine moiety, linked to nicotinonitriles, <i>N</i>-coumarin-2-furanone, and pyrrole-linked chromene derivatives using nanocatalysts with a Fe₃O₄ core are described. This review covers the synthetic developments in the recent years 2012–2021 and focuses entirely on the synthesis of coumarins in the presence of magnetic nanocatalysts using greener approaches such as solvent-free conditions or deploying alternative activation methods, namely microwave or ultrasound irradiation.</p></div>","PeriodicalId":54344,"journal":{"name":"Topics in Current Chemistry","volume":"381 1","pages":""},"PeriodicalIF":8.6,"publicationDate":"2022-11-12","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"4507340","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"化学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Recent Advances in the Use of Dimethyl Sulfoxide as a Synthon in Organic Chemistry","authors":"Hao Lu,&nbsp;Zhou Tong,&nbsp;Lifen Peng,&nbsp;Zhiqing Wang,&nbsp;Shuang-Feng Yin,&nbsp;Nobuaki Kambe,&nbsp;Renhua Qiu","doi":"10.1007/s41061-022-00411-8","DOIUrl":"10.1007/s41061-022-00411-8","url":null,"abstract":"<div><p>Dimethyl sulfoxide (DMSO), as extremely important aprotic polar solvent and reaction medium, has attracted widespread attention from chemists in recent years due to its wide range of uses and the multiple functions it displays in various chemical processes. Especially in the past decade, dimethyl sulfoxide has become increasingly favored as a synthon in organic chemistry, resulting in great progress in this research field. In this context, this review provides a comprehensive summary of the literature on the recent progress in organic synthesis using dimethyl sulfoxide as a synthon, covering all the reports from 1 January 2016 to 11 May 2022. This type of reaction is mainly performed by transferring one or more units of dimethyl sulfoxide, such as oxygen (–O–, =O), methyl (–CH₃), methylene (–CH₂–), methylidene (=CH₂), methine (=CH–), donor of formylation (–CHO), sulfur (–S–), methylthio (–SMe), methyl sulfoxide (–SOMe), donor of methyl thiomethylation (–CH₂SMe), or donor of methyl sulfoxide methylation (–CH₂SOMe), to the target molecules. At the same time, we hope that this review will stimulate future studies and promote developments in this area.</p><h3>Graphical Abstract</h3>\u0000 <figure><div><div><div><picture><source><img></source></picture></div></div></div></figure>\u0000 </div>","PeriodicalId":54344,"journal":{"name":"Topics in Current Chemistry","volume":"380 6","pages":""},"PeriodicalIF":8.6,"publicationDate":"2022-10-28","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"5096172","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"化学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Obtaining Water from Air Using Porous Metal–Organic Frameworks (MOFs)","authors":"Brij Mohan,&nbsp;Suresh Kumar,&nbsp;Quansheng Chen","doi":"10.1007/s41061-022-00410-9","DOIUrl":"10.1007/s41061-022-00410-9","url":null,"abstract":"<div><p>Water collection from moisture in air, i.e., atmospheric water harvesting, is an urgent future need for society. It can be used for water production everywhere and anytime as an alternative water source in remote areas. However, water harvesting and collection usually relies on desalination, fog, and dewing harvesting, which are energy intensive. In this respect, metal–organic frameworks (MOFs) have broad applicability for water harvesting in water-scarce areas; therefore, the current discussion focuses on this approach. Furthermore, recent progress on MOFs for moisture harvesters is critically discussed. In addition, the design, operation, and water harvesting mechanisms of MOFs are studied. Finally, we discuss critical points for future research for the design of new MOFs as moisture harvesters for use in practical applications.</p><h3>Graphical Abstract</h3><p>MOF adsorbents offer excellent operating capacity in various temperature and pressure ranges. Rational water harvesters can thus be developed by adjusting structural properties such as the porosity, functionalities, and metal centers, thereby enabling new devices to produce water even in remote areas.</p>\u0000 <figure><div><div><div><picture><source><img></source></picture></div></div></div></figure>\u0000 </div>","PeriodicalId":54344,"journal":{"name":"Topics in Current Chemistry","volume":"380 6","pages":""},"PeriodicalIF":8.6,"publicationDate":"2022-10-21","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"4836358","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"化学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Isocyanide-Based Multicomponent Reactions in Water: Advanced Green Tools for the Synthesis of Heterocyclic Compounds","authors":"Tahereh Nasiriani,&nbsp;Siamak Javanbakht,&nbsp;Mohammad Taghi Nazeri,&nbsp;Hassan Farhid,&nbsp;Vida Khodkari,&nbsp;Ahmad Shaabani","doi":"10.1007/s41061-022-00403-8","DOIUrl":"10.1007/s41061-022-00403-8","url":null,"abstract":"<div><p>Reaction rate acceleration using green methods is an intriguing area of research for chemists. In this regard, water as a “green solvent” plays a crucial role in the acceleration of some organic transformations and reveals exclusive selectivity and reactivity in comparison with conventional organic solvents. In particular, multicomponent reactions (MCRs) as sustainable tools lead to the rapid generation of small-molecule libraries in water and aqueous media due to the prominent role of the hydrophobic effect. MCRs, as diversity-oriented synthesis (DOS) methods, have great efficiency with simple operations, atom, pot, and step economy synthesis, and mechanistic beauty. Among diverse classes of MCRs, isocyanide-based multicomponent reactions (I-MCRs), as sustainable and versatile reactions, have gained considerable attention in the synthesis of diverse heterocycle rings, especially in drug design because of the peculiar nature of isocyanide as a particular active reactant. I-MCRs that are performed in water are mild, environmentally friendly, and easily controlled, and have a reduced number of workup, purification, and extraction steps, which fit well with the advantages of “green” chemistry. Performing these powerful organic transformations in water and aqueous media is accompanied by acceleration owing to negative activation volumes, which originate from connecting several reactants together to generate a single product. It should be noted that the combination of MCR strategy and aqueous phase reaction is of growing interest for the development of sustainable synthetic techniques in organic conversions. However, an exclusive account focusing on the recent progress in eco-friendly I-MCRs for the construction of heterocycles in water and aqueous media is particularly lacking. This review highlights the progress of various kinds of I-MCRs in water and aqueous media as benign methods for the efficient construction of vital heterocyclic scaffolds, with a critical discussion of the subject in the period 2000–2021. We hope that this themed collection will be of interest and beneficial for organic and pharmaceutical chemists and will inspire more reaction development in this fascinating field.</p><h3>Graphical Abstract</h3>\u0000 <figure><div><div><div><picture><source><img></source></picture></div></div></div></figure>\u0000 </div>","PeriodicalId":54344,"journal":{"name":"Topics in Current Chemistry","volume":"380 6","pages":""},"PeriodicalIF":8.6,"publicationDate":"2022-09-22","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"4882689","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"化学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Recent Trends in Photocatalytic Enantioselective Reactions","authors":"Renu Verma,&nbsp;Palvi Jindal,&nbsp;Jagdish Prasad,&nbsp;S. L. Kothari,&nbsp;Narendra Pal Lamba,&nbsp;Anshu Dandia,&nbsp;Rama Kanwar Khangarot,&nbsp;Manmohan Singh Chauhan","doi":"10.1007/s41061-022-00402-9","DOIUrl":"10.1007/s41061-022-00402-9","url":null,"abstract":"<div><p>Enantioselective synthesis through photocatalysis is one of the highly preferred approaches towards preparation of optically active compounds. This review elaborates and critically analyzes the different strategies of photocatalytic enantioselective reactions through H-bonding, transition metal catalysis, phase-transfer catalysis (PTC), chiral Lewis acid catalysis, <i>N</i>-heterocyclic carbene catalysis, and amine catalysis, and also explores ion pairs. In addition, it explains the different catalysis modes with multifunctional approaches for enantioselective photocatalytic reactions.</p></div>","PeriodicalId":54344,"journal":{"name":"Topics in Current Chemistry","volume":"380 6","pages":""},"PeriodicalIF":8.6,"publicationDate":"2022-09-16","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"4663743","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"化学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"In situ and Operando Spectroscopies in Photocatalysis: Powerful Techniques for a Better Understanding of the Performance and the Reaction Mechanism","authors":"Houeida Issa Hamoud,&nbsp;Lukasz Wolski,&nbsp;Ilia Pankin,&nbsp;Miguel A. Bañares,&nbsp;Marco Daturi,&nbsp;Mohamad El-Roz","doi":"10.1007/s41061-022-00387-5","DOIUrl":"10.1007/s41061-022-00387-5","url":null,"abstract":"<div><p>In photocatalysis, a set of elemental steps are involved together at different timescales to govern the overall efficiency of the process. These steps are divided as follow: (1) photon absorption and excitation (in femtoseconds), (2) charge separation (femto- to picoseconds), (3) charge carrier diffusion/transport (nano- to microseconds), and (4 and 5) reactant activation/conversion and mass transfer (micro- to milliseconds). The identification and quantification of these steps, using the appropriate tool/technique, can provide the guidelines to emphasize the most influential key parameter that improve the overall efficiency and to develop the “photocatalyst by design” concept. In this review, the identification/quantification of reactant activation/conversion and mass transfer (steps 4 and 5) is discussed in details using the in situ/<i>operando</i> techniques, especially the infrared (IR), Raman, and X-ray absorption spectroscopy (XAS). The use of these techniques in photocatalysis was highlighted by the most recent and conclusive case studies which allow a better characterization of the active site and reveal the reaction pathways in order to establish a structure–performance relationship. In each case study, the reaction conditions and the reactor design for photocatalysis (pressure, temperature, concentration, etc.) were thoroughly discussed. In the last part, some examples in the use of time-resolved techniques (time-resolved FTIR, photoluminescence, and transient absorption) are also presented as an author’s guideline to study the elemental steps in photocatalysis at shorter timescale (ps, ns, and µs).</p></div>","PeriodicalId":54344,"journal":{"name":"Topics in Current Chemistry","volume":"380 5","pages":""},"PeriodicalIF":8.6,"publicationDate":"2022-08-11","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://link.springer.com/content/pdf/10.1007/s41061-022-00387-5.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"40709579","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"化学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Covalent and Non-covalent Functionalized Nanomaterials for Environmental Restoration","authors":"Shizhong Zhang,&nbsp;Sumeet Malik,&nbsp;Nisar Ali,&nbsp;Adnan Khan,&nbsp;Muhammad Bilal,&nbsp;Kashif Rasool","doi":"10.1007/s41061-022-00397-3","DOIUrl":"10.1007/s41061-022-00397-3","url":null,"abstract":"<div><p>Nanotechnology has emerged as an extraordinary and rapidly developing discipline of science. It has remolded the fate of the whole world by providing diverse horizons in different fields. Nanomaterials are appealing because of their incredibly small size and large surface area. Apart from the naturally occurring nanomaterials, synthetic nanomaterials are being prepared on large scales with different sizes and properties. Such nanomaterials are being utilized as an innovative and green approach in multiple fields. To expand the applications and enhance the properties of the nanomaterials, their functionalization and engineering are being performed on a massive scale. The functionalization helps to add to the existing useful properties of the nanomaterials, hence broadening the scope of their utilization. A large class of covalent and non-covalent functionalized nanomaterials (FNMs) including carbons, metal oxides, quantum dots, and composites of these materials with other organic or inorganic materials are being synthesized and used for environmental remediation applications including wastewater treatment. This review summarizes recent advances in the synthesis, reporting techniques, and applications of FNMs in adsorptive and photocatalytic removal of pollutants from wastewater. Future prospects are also examined, along with suggestions for attaining massive benefits in the areas of FNMs.</p></div>","PeriodicalId":54344,"journal":{"name":"Topics in Current Chemistry","volume":"380 5","pages":""},"PeriodicalIF":8.6,"publicationDate":"2022-08-11","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9372017/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"40709581","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"化学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Plasmonic Hybrid Nanostructures in Photocatalysis: Structures, Mechanisms, and Applications","authors":"Rajeshreddy Ninakanti,&nbsp;Fons Dingenen,&nbsp;Rituraj Borah,&nbsp;Hannelore Peeters,&nbsp;Sammy W. Verbruggen","doi":"10.1007/s41061-022-00390-w","DOIUrl":"10.1007/s41061-022-00390-w","url":null,"abstract":"<div><p>(Sun)Light is an abundantly available sustainable source of energy that has been used in catalyzing chemical reactions for several decades now. In particular, studies related to the interaction of light with plasmonic nanostructures have been receiving increased attention. These structures display the unique property of localized surface plasmon resonance, which converts light of a specific wavelength range into hot charge carriers, along with strong local electromagnetic fields, and/or heat, which may all enhance the reaction efficiency in their own way. These unique properties of plasmonic nanoparticles can be conveniently tuned by varying the metal type, size, shape, and dielectric environment, thus prompting a research focus on rationally designed plasmonic hybrid nanostructures. In this review, the term “hybrid” implies nanomaterials that consist of multiple plasmonic or non-plasmonic materials, forming complex configurations in the geometry and/or at the atomic level. We discuss the synthetic techniques and evolution of such hybrid plasmonic nanostructures giving rise to a wide variety of material and geometric configurations. Bimetallic alloys, which result in a new set of opto-physical parameters, are compared with core–shell configurations. For the latter, the use of metal, semiconductor, and polymer shells is reviewed. Also, more complex structures such as Janus and antenna reactor composites are discussed. This review further summarizes the studies exploiting plasmonic hybrids to elucidate the plasmonic-photocatalytic mechanism. Finally, we review the implementation of these plasmonic hybrids in different photocatalytic application domains such as H₂ generation, CO₂ reduction, water purification, air purification, and disinfection.</p></div>","PeriodicalId":54344,"journal":{"name":"Topics in Current Chemistry","volume":"380 5","pages":""},"PeriodicalIF":8.6,"publicationDate":"2022-08-11","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"40603097","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"化学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}