Topics in Current Chemistry最新文献_第4页

Characterization Methodology and Activity Evaluation of Solar-Driven Catalysts for Environmental Remediation 环境修复用太阳能驱动催化剂的表征方法及活性评价

IF 8.6 2区化学

Topics in Current Chemistry Pub Date : 2022-08-11 DOI: 10.1007/s41061-022-00394-6

Mina Guli, Elsayed T. Helmy, Jenny Schneider, Gui Lu, Jia Hong Pan

引用次数: 5

Glycopolymer-Based Materials: Synthesis, Properties, and Biosensing Applications 基于糖基共聚物的材料:合成、性能和生物传感应用

IF 8.6 2区化学

Topics in Current Chemistry Pub Date : 2022-08-11 DOI: 10.1007/s41061-022-00395-5

Mohammad R. Thalji, Amal Amin Ibrahim, Kwok Feng Chong, Alexander V. Soldatov, Gomaa A. M. Ali

{"title":"Glycopolymer-Based Materials: Synthesis, Properties, and Biosensing Applications","authors":"Mohammad R. Thalji, Amal Amin Ibrahim, Kwok Feng Chong, Alexander V. Soldatov, Gomaa A. M. Ali","doi":"10.1007/s41061-022-00395-5","DOIUrl":"10.1007/s41061-022-00395-5","url":null,"abstract":"<div><p>Glycopolymer materials have emerged as a significant biopolymer class that has piqued the scientific community's attention due to their potential applications. Recently, they have been found to be a unique synthetic biomaterial; glycopolymer materials have also been used for various applications, including direct therapeutic methods, medical adhesives, drug/gene delivery systems, and biosensor applications. Therefore, for the next stage of biomaterial research, it is essential to understand current breakthroughs in glycopolymer-based materials research. This review discusses the most widely utilized synthetic methodologies for glycopolymer-based materials, their properties based on structure–function interactions, and the significance of these materials in biosensing applications, among other topics. When creating glycopolymer materials, contemporary polymerization methods allow precise control over molecular weight, molecular weight distribution, chemical activity, and polymer architecture. This review concludes with a discussion of the challenges and complexities of glycopolymer-based biosensors, in addition to their potential applications in the future.</p><h3>Graphical Abstract</h3>\u0000 <div><figure><div><div><picture><source><img></source></picture></div></div></figure></div>\u0000 </div>","PeriodicalId":54344,"journal":{"name":"Topics in Current Chemistry","volume":"380 5","pages":""},"PeriodicalIF":8.6,"publicationDate":"2022-08-11","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"40685561","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"化学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 7

Phosphorescent Ir(III) Complexes for Biolabeling and Biosensing 用于生物标记和生物传感的磷光Ir(III)配合物

IF 8.6 2区化学

Topics in Current Chemistry Pub Date : 2022-08-10 DOI: 10.1007/s41061-022-00389-3

Byung Hak Jhun, Dayoon Song, Soo Young Park, Youngmin You

{"title":"Phosphorescent Ir(III) Complexes for Biolabeling and Biosensing","authors":"Byung Hak Jhun, Dayoon Song, Soo Young Park, Youngmin You","doi":"10.1007/s41061-022-00389-3","DOIUrl":"10.1007/s41061-022-00389-3","url":null,"abstract":"<div><p>Cyclometalated Ir(III) complexes exhibit strong phosphorescence emission with lifetime of submicroseconds to several microseconds at room temperature. Their synthetic versatility enables broad control of physical properties, such as charge and lipophilicity, as well as emission colors. These favorable properties have motivated the use of Ir(III) complexes in luminescent bioimaging applications. This review examines the recent progress in the development of phosphorescent biolabels and sensors based on Ir(III) complexes. It begins with a brief introduction about the basic principles of the syntheses and photophysical processes of cyclometalated Ir(III) complexes. Focus is placed on illustrating the broad imaging utility of Ir(III) complexes. Phosphorescent labels illuminating intracellular organelles, including mitochondria, lysosomes, and cell membranes, are summarized. Ir(III) complexes capable of visualization of tumor spheroids and parasites are also introduced. Facile chemical modification of the cyclometalating ligands endows the Ir(III) complexes with strong sensing ability. Sensors of temperature, pH, CO<sub>2</sub>, metal ions, anions, biosulfur species, reactive oxygen species, peptides, and viscosity have recently been added to the molecular imaging tools. This diverse utility demonstrates the potential of phosphorescent Ir(III) complexes toward bioimaging applications.</p></div>","PeriodicalId":54344,"journal":{"name":"Topics in Current Chemistry","volume":"380 5","pages":""},"PeriodicalIF":8.6,"publicationDate":"2022-08-10","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"40708023","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"化学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 1

Post-complexation Functionalization of Cyclometalated Iridium(III) Complexes and Applications to Biomedical and Material Sciences 环金属化铱配合物的络合后功能化及其在生物医学和材料科学中的应用

IF 8.6 2区化学

Topics in Current Chemistry Pub Date : 2022-08-10 DOI: 10.1007/s41061-022-00401-w

Shin Aoki, Kenta Yokoi, Yosuke Hisamatsu, Chandrasekar Balachandran, Yuichi Tamura, Tomohiro Tanaka

{"title":"Post-complexation Functionalization of Cyclometalated Iridium(III) Complexes and Applications to Biomedical and Material Sciences","authors":"Shin Aoki, Kenta Yokoi, Yosuke Hisamatsu, Chandrasekar Balachandran, Yuichi Tamura, Tomohiro Tanaka","doi":"10.1007/s41061-022-00401-w","DOIUrl":"10.1007/s41061-022-00401-w","url":null,"abstract":"<div><p>Cyclometalated iridium(III) (Ir(III)) complexes exhibit excellent photophysical properties that include large Stokes shift, high emission quantum yields, and microsecond-order emission lifetimes, due to low-lying metal-to-ligand charge transfer (spin-forbidden singlet–triplet (<sup>3</sup>MLCT) transition). As a result, analogs have been applied for research not only in the material sciences, such as the development of organic light-emitting diodes (OLEDs), but also for photocatalysts, bioimaging probes, and anticancer reagents. Although a variety of methods for the synthesis and the applications of functionalized cyclometalated iridium complexes have been reported, functional groups are generally introduced to the ligands prior to the complexation with Ir salts. Therefore, it is difficult to introduce thermally unstable functional groups such as peptides and sugars due to the harsh reaction conditions such as the high temperatures used in the complexation with Ir salts. In this review, the functionalization of Ir complexes after the formation of cyclometalated Ir complexes and their biological and material applications are described. These methods are referred to as “post-complexation functionalization (PCF).” In this review, applications of PCF to the design and synthesis of Ir(III) complexes that exhibit blue –red and white color emissions, luminescence pH probes, luminescent probes of cancer cells, compounds that induce cell death in cancer cells, and luminescent complexes that have long emission lifetimes are summarized.</p></div>","PeriodicalId":54344,"journal":{"name":"Topics in Current Chemistry","volume":"380 5","pages":""},"PeriodicalIF":8.6,"publicationDate":"2022-08-10","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"40684586","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"化学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 5

Functionalized Triazines and Tetrazines: Synthesis and Applications 功能化三嗪和四嗪:合成及应用

IF 8.6 2区化学

Topics in Current Chemistry Pub Date : 2022-06-23 DOI: 10.1007/s41061-022-00385-7

Joydip Mondal, Akella Sivaramakrishna

{"title":"Functionalized Triazines and Tetrazines: Synthesis and Applications","authors":"Joydip Mondal, Akella Sivaramakrishna","doi":"10.1007/s41061-022-00385-7","DOIUrl":"10.1007/s41061-022-00385-7","url":null,"abstract":"<div><p>The molecules possessing triazine and tetrazine moieties belong to a special class of heterocyclic compounds. Both triazines and tetrazines are building blocks and have provided a new dimension to the design of biologically important organic molecules. Several of their derivatives with fine-tuned electronic properties have been identified as multifunctional, adaptable, switchable, remarkably antifungal, anticancer, antiviral, antitumor, cardiotonic, anti-HIV, analgesic, anti-protozoal, etc. The objective of this review is to comprehensively describe the recent developments in synthesis, coordination properties, and various applications of triazine and tetrazine molecules. The rich literature demonstrates various synthetic routes for a variety of triazines and tetrazines through microwave-assisted, solid-phase, metal-based, [4+2] cycloaddition, and multicomponent one-pot reactions. Synthetic approaches contain linear, angular, and fused triazine and tetrazine heterocycles through a combinatorial method. Notably, the triazines and tetrazines undergo a variety of organic transformations, including electrophilic addition, coupling, nucleophilic displacement, and intramolecular cyclization. The mechanistic aspects of these heterocycles are discussed in a detailed way. The bioorthogonal application of these polyazines with various strained alkenes and alkynes provides a new prospect for investigations in chemical biology. This review systematically encapsulates the recent developments and challenges in the synthesis and possible potential applications of various triazine and tetrazine systems.</p><h3>Graphical Abstract</h3>\u0000 <figure><div><div><div><picture><source><img></source></picture></div></div></div></figure>\u0000 </div>","PeriodicalId":54344,"journal":{"name":"Topics in Current Chemistry","volume":"380 5","pages":""},"PeriodicalIF":8.6,"publicationDate":"2022-06-23","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"4898541","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"化学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 9

Conjugated Polymer Polypyrrole Nanostructures: Synthesis and Photocatalytic Applications 共轭高分子聚吡咯纳米结构:合成及其光催化应用

IF 8.6 2区化学

Topics in Current Chemistry Pub Date : 2022-06-18 DOI: 10.1007/s41061-022-00388-4

Xiaojiao Yuan, Hynd Remita

引用次数: 9

Evolution of the Automatic Rhodopsin Modeling (ARM) Protocol 自动视紫红质建模(ARM)协议的发展

IF 8.6 2区化学

Topics in Current Chemistry Pub Date : 2022-03-15 DOI: 10.1007/s41061-022-00374-w

Laura Pedraza-González, Leonardo Barneschi, Daniele Padula, Luca De Vico, Massimo Olivucci

引用次数: 6

Enantioselective Allylic C–H Bond Oxidation of Olefins Using Copper Complexes of Chiral Oxazoline Based Ligands 手性恶唑啉配体铜配合物对烯丙基碳氢键氧化烯烃的影响

IF 8.6 2区化学

Topics in Current Chemistry Pub Date : 2022-03-10 DOI: 10.1007/s41061-022-00375-9

Saadi Samadi, Hamid Arvinnezhad, Saber Nazari, Shiva Majidian

引用次数: 5

Reaction Space Projector (ReSPer) for Visualizing Dynamic Reaction Routes Based on Reduced-Dimension Space 基于降维空间的动态反应路径可视化反应空间投影(ReSPer)

IF 8.6 2区化学

Topics in Current Chemistry Pub Date : 2022-03-10 DOI: 10.1007/s41061-022-00377-7

Takuro Tsutsumi, Yuriko Ono, Tetsuya Taketsugu

{"title":"Reaction Space Projector (ReSPer) for Visualizing Dynamic Reaction Routes Based on Reduced-Dimension Space","authors":"Takuro Tsutsumi, Yuriko Ono, Tetsuya Taketsugu","doi":"10.1007/s41061-022-00377-7","DOIUrl":"10.1007/s41061-022-00377-7","url":null,"abstract":"<div><p>To analyze chemical reaction dynamics based on a reaction path network, we have developed the “Reaction Space Projector” (ReSPer) method with the aid of the dimensionality reduction method. This program has two functions: the construction of a reduced-dimensionality reaction space from a molecular structure dataset, and the projection of dynamic trajectories into the low-dimensional reaction space. In this paper, we apply ReSPer to isomerization and bifurcation reactions of the Au<sub>5</sub> cluster and succeed in analyzing dynamic reaction routes involved in multiple elementary reaction processes, constructing complicated networks (called “closed islands”) of nuclear permutation-inversion (NPI) isomerization reactions, and elucidating dynamic behaviors in bifurcation reactions with reference to bundles of trajectories. Interestingly, in the second application, we find a correspondence between the contribution ratios in the ability to visualize and the symmetry of the morphology of closed islands. In addition, the third application suggests the existence of boundaries that determine the selectivity in bifurcation reactions, which was discussed in the phase space. The ReSPer program is a versatile and robust tool to clarify dynamic reaction mechanisms based on the reduced-dimensionality reaction space without prior knowledge of target reactions.</p></div>","PeriodicalId":54344,"journal":{"name":"Topics in Current Chemistry","volume":"380 3","pages":""},"PeriodicalIF":8.6,"publicationDate":"2022-03-10","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://link.springer.com/content/pdf/10.1007/s41061-022-00377-7.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"4734309","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"化学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 3

Recent Progress in Indacenodithiophene-Based Acceptor Materials for Non-Fullerene Organic Solar Cells 非富勒烯有机太阳能电池用吲哚二噻吩基受体材料的研究进展

IF 8.6 2区化学

Topics in Current Chemistry Pub Date : 2022-03-05 DOI: 10.1007/s41061-022-00372-y

Rashid Ilmi, Houda Al-Sharji, Muhammad S. Khan

{"title":"Recent Progress in Indacenodithiophene-Based Acceptor Materials for Non-Fullerene Organic Solar Cells","authors":"Rashid Ilmi, Houda Al-Sharji, Muhammad S. Khan","doi":"10.1007/s41061-022-00372-y","DOIUrl":"10.1007/s41061-022-00372-y","url":null,"abstract":"<div><p>Domesticating solar energy by exploiting photovoltaic technology has become a quintessential strategy for future global energy production. Since 2015, non-fullerene organic solar cells (NF-OSC) have attracted a great deal of attention owing to the marvellous properties of non-fullerene acceptors (NFA) such as structural versability, broad absorption, suitable energy levels, tunable charge transport and morphology, leading to remarkable accomplishments in power conversion efficiency (PCE) from 1% to nearly 20%. One class of materials is provided by the fused ring aromatic indacenodithiophene (IDT) and its derivatives, which are emerging continuously as promising next-generation building blocks to construct high performance photovoltaic materials. Encouraging PCEs of more than 15% have been achieved in their binary NF-OSCs, while careful device engineering and proper amalgamation of a third component have led to PCEs of almost 18% in ternary devices. This review surveys recent developments in the area of IDT-based materials for photovoltaic applications. Different strategies to develop efficient IDT-based NFA and factors influencing the bandgaps, molecular energy levels, charge transport properties, and film morphologies, as well as the photovoltaic performance of these materials, are discussed.</p><h3>Graphical abstract</h3>\u0000 <figure><div><div><div><picture><source><img></source></picture></div></div></div></figure>\u0000 </div>","PeriodicalId":54344,"journal":{"name":"Topics in Current Chemistry","volume":"380 3","pages":""},"PeriodicalIF":8.6,"publicationDate":"2022-03-05","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"4220803","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"化学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 6