Topics in Current Chemistry最新文献_第5页

The Role of Metal Nanoparticles in Promoting Photocatalysis by TiO2 金属纳米颗粒在促进TiO2光催化中的作用

IF 8.6 2区化学

Topics in Current Chemistry Pub Date : 2022-03-03 DOI: 10.1007/s41061-022-00373-x

Michael Bowker, Christopher O’Rourke, Andrew Mills

{"title":"The Role of Metal Nanoparticles in Promoting Photocatalysis by TiO2","authors":"Michael Bowker, Christopher O’Rourke, Andrew Mills","doi":"10.1007/s41061-022-00373-x","DOIUrl":"10.1007/s41061-022-00373-x","url":null,"abstract":"<div><p>In this review, we highlight the role played by metal nanoparticles (NPs) in photocatalytic oxidation with titania as a support. This is presented in two parts, namely, partial photo-oxidation in which an organic sacrificial agent is oxidised in anaerobic conditions to produce hydrogen (photo-reforming), and photo-oxidative mineralisation of organics in aerobic conditions. We present some rules for such reactions that dictate which organic molecules can react readily, and which metals are likely to be useful for such reactions. Generally, the presence of metal NPs enhances enormously the ability of titania to yield hydrogen from photo-reforming, and a wide range of molecules can be used, including biomass. The metal NPs most used are those that are easily reduced, that is, the precious metals. The large enhancement in rate seen with metal for hydrogen production is not so extreme for the oxidation reactions, but is still significant. An important factor in all of this catalysis is the nature of the interaction between the metal NPs, which can play a multiplicity of chemical and electronic roles, and the photoactive support. A sharp dependency of rate on loading of metal is found, with maximum rates at ~0.5–2 wt% loading, depending on the metal used. The source of this dependency is the bifunctional nature of the system, in which the intimacy of both materials is crucial to performance. This rate variation is linked to the interface between the two, which is then linked to the size of the metal NPs. In fact, the rate is proportional to an area adjacent to the metal particles that we call the expanding photocatalytic area and overlap (EPAO) kinetic model. This model describes the dependence well. Rising rates with increasing coverage of particles is associated with increase in this total area but, at the maximum, these areas overlap and at higher loadings the available active area diminishes, reproducing the observed behaviour well.</p></div>","PeriodicalId":54344,"journal":{"name":"Topics in Current Chemistry","volume":"380 3","pages":""},"PeriodicalIF":8.6,"publicationDate":"2022-03-03","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://link.springer.com/content/pdf/10.1007/s41061-022-00373-x.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"4133412","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"化学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 10

Total RNA Synthesis and its Covalent Labeling Innovation 总RNA合成及其共价标记创新

IF 8.6 2区化学

Topics in Current Chemistry Pub Date : 2022-02-26 DOI: 10.1007/s41061-022-00371-z

Hongling Zhou, Yuanyuan Li, Youfang Gan, Rui Wang

{"title":"Total RNA Synthesis and its Covalent Labeling Innovation","authors":"Hongling Zhou, Yuanyuan Li, Youfang Gan, Rui Wang","doi":"10.1007/s41061-022-00371-z","DOIUrl":"10.1007/s41061-022-00371-z","url":null,"abstract":"<div><p>RNA plays critical roles in a wide range of physiological processes. For example, it is well known that RNA plays an important role in regulating gene expression, cell proliferation, and differentiation, and many other chemical and biological processes. However, the research community still suffers from limited approaches that can be applied to readily visualize a specific RNA-of-interest (ROI). Several methods can be used to track RNAs; these rely mainly on biological properties, namely, hybridization, aptamer, reporter protein, and protein binding. With respect to covalent approaches, very few cases have been reported. Happily, several new methods for efficient labeling studies of ROIs have been demonstrated successfully in recent years. Additionally, methods employed for the detection of ROIs by RNA modifying enzymes have also proved feasible. Several approaches, namely, phosphoramidite chemistry, in vitro transcription reactions, co-transcription reactions, chemical post-modification, RNA modifying enzymes, ligation, and other methods targeted at RNA labeling have been revealed in the past decades. To illustrate the most recent achievements, this review aims to summarize the most recent research in the field of synthesis of RNAs-of-interest bearing a variety of unnatural nucleosides, the subsequent RNA labeling research via biocompatible ligation, and beyond.</p></div>","PeriodicalId":54344,"journal":{"name":"Topics in Current Chemistry","volume":"380 3","pages":""},"PeriodicalIF":8.6,"publicationDate":"2022-02-26","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"5400303","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"化学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 3

NAST: Nonadiabatic Statistical Theory Package for Predicting Kinetics of Spin-Dependent Processes 用于预测自旋相关过程动力学的非绝热统计理论包

IF 8.6 2区化学

Topics in Current Chemistry Pub Date : 2022-02-24 DOI: 10.1007/s41061-022-00366-w

Vsevolod D. Dergachev, Mitra Rooein, Ilya D. Dergachev, Aleksandr O. Lykhin, Robert C. Mauban, Sergey A. Varganov

{"title":"NAST: Nonadiabatic Statistical Theory Package for Predicting Kinetics of Spin-Dependent Processes","authors":"Vsevolod D. Dergachev, Mitra Rooein, Ilya D. Dergachev, Aleksandr O. Lykhin, Robert C. Mauban, Sergey A. Varganov","doi":"10.1007/s41061-022-00366-w","DOIUrl":"10.1007/s41061-022-00366-w","url":null,"abstract":"<div><p>We present a nonadiabatic statistical theory (NAST) package for predicting kinetics of spin-dependent processes, such as intersystem crossings, spin-forbidden unimolecular reactions, and spin crossovers. The NAST package can calculate the probabilities and rates of transitions between the electronic states of different spin multiplicities. Both the microcanonical (energy-dependent) and canonical (temperature-dependent) rate constants can be obtained. Quantum effects, including tunneling, zero-point vibrational energy, and reaction path interference, can be accounted for. In the limit of an adiabatic unimolecular reaction proceeding on a single electronic state, NAST reduces to the traditional transition state theory. Because NAST requires molecular properties at only a few points on potential energy surfaces, it can be applied to large molecular systems, used with accurate high-level electronic structure methods, and employed to study slow nonadiabatic processes. The essential NAST input data include the nuclear Hessian at the reactant minimum, as well as the nuclear Hessians, energy gradients, and spin–orbit coupling at the minimum energy crossing point (MECP) between two states. The additional computational tools included in the NAST package can be used to extract the required input data from the output files of electronic structure packages, calculate the effective Hessian at the MECP, and fit the reaction coordinate for more advanced NAST calculations. We describe the theory, its implementation, and three examples of application to different molecular systems.</p></div>","PeriodicalId":54344,"journal":{"name":"Topics in Current Chemistry","volume":"380 2","pages":""},"PeriodicalIF":8.6,"publicationDate":"2022-02-24","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"4927269","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"化学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 5

Sonochemical Protocols for Heterocyclic Synthesis: A Representative Review 杂环合成的声化学方法:一个有代表性的综述

IF 8.6 2区化学

Topics in Current Chemistry Pub Date : 2022-02-12 DOI: 10.1007/s41061-022-00369-7

Meena Devi, Rahul Singh, Jayant Sindhu, Ashwani Kumar, Sohan Lal, Ramesh Kumar, Khalid Hussain, Megha Sachdeva, Devender Singh, Parvin Kumar

{"title":"Sonochemical Protocols for Heterocyclic Synthesis: A Representative Review","authors":"Meena Devi, Rahul Singh, Jayant Sindhu, Ashwani Kumar, Sohan Lal, Ramesh Kumar, Khalid Hussain, Megha Sachdeva, Devender Singh, Parvin Kumar","doi":"10.1007/s41061-022-00369-7","DOIUrl":"10.1007/s41061-022-00369-7","url":null,"abstract":"<div><p>In the present era of the industrial revolution, we all are familiar with ever-increasing environmental pollution released from various chemical processes. Chemical production has had a severe impact on the environment and human health. For the betterment of our environment, the chemical community has turned their interest to developing green, harmless and sustainable synthetic processes. To accomplish these goals of green chemistry, the extraordinary properties of sonication play an important role. It is well known that sonochemistry can make decisive contributions to creating high pressures of almost 1000 atm and very high temperatures in the range of 4500–5000 °C. The implementation of ultrasound in chemical transformations somehow fulfils the measures of green chemistry, as it reduces energy consumption, enhances product selectivity, and uses lesser amounts of hazardous chemicals and solvents. Furthermore, heterocyclic synthesis under ultrasonication offers several environmental and process-related advantages compared with conventional methods. The remarkable contribution of ultrasonics to the development of green and sustainable synthetic routes inspired us to write this article. Herein, we have discussed only some of the various synthetic methodologies developed for the construction of heterocyclic cores under ultrasonic irradiation, accompanied by mechanistic insights. In some cases, a comparison between sonochemical conditions and conventional conditions has also been investigated. We emphasized principally ‘up to date’ developments on various sono-accelerated chemical transformations comprising <i>aza</i>-Michael, aldol reactions, C–C couplings, oxidation, cycloadditions, multi-component reactions, etc. for the synthesis of heterocycles.</p></div>","PeriodicalId":54344,"journal":{"name":"Topics in Current Chemistry","volume":"380 2","pages":""},"PeriodicalIF":8.6,"publicationDate":"2022-02-12","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://link.springer.com/content/pdf/10.1007/s41061-022-00369-7.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"4793225","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"化学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 3

Bioactive Chitosan-Based Organometallic Scaffolds for Tissue Engineering and Regeneration 生物活性壳聚糖基有机金属支架用于组织工程和再生

IF 8.6 2区化学

Topics in Current Chemistry Pub Date : 2022-02-12 DOI: 10.1007/s41061-022-00364-y

Solmaz Zakhireh, Jaleh Barar, Khosro Adibkia, Younes Beygi-Khosrowshahi, Marziyeh Fathi, Hossein Omidain, Yadollah Omidi

{"title":"Bioactive Chitosan-Based Organometallic Scaffolds for Tissue Engineering and Regeneration","authors":"Solmaz Zakhireh, Jaleh Barar, Khosro Adibkia, Younes Beygi-Khosrowshahi, Marziyeh Fathi, Hossein Omidain, Yadollah Omidi","doi":"10.1007/s41061-022-00364-y","DOIUrl":"10.1007/s41061-022-00364-y","url":null,"abstract":"<div><p>Captivating achievements in developing advanced hybrid biostructures through integrating natural biopolymers with inorganic materials (e.g., metals and metalloids) have paved the way towards the application of bioactive organometallic scaffolds (OMSs) in tissue engineering and regenerative medicine (TERM). Of various biopolymers, chitosan (CS) has been used widely for the development of bioactive OMSs, in large part due to its unique characteristics (e.g., biocompatibility, biodegradability, surface chemistry, and functionalization potential). In integration with inorganic elements, CS has been used to engineer advanced biomimetic matrices to accommodate both embedded cells and drug molecules and serve as scaffolds in TERM. The use of the CS-based OMSs is envisioned to provide a new pragmatic potential in TERM and even in precision medicine. In this review, we aim to elaborate on recent achievements in a variety of CS/metal, CS/metalloid hybrid scaffolds, and discuss their applications in TERM. We also provide comprehensive insights into the formulation, surface modification, characterization, biocompatibility, and cytotoxicity of different types of CS-based OMSs.</p></div>","PeriodicalId":54344,"journal":{"name":"Topics in Current Chemistry","volume":"380 2","pages":""},"PeriodicalIF":8.6,"publicationDate":"2022-02-12","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"4490417","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"化学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 6

Vision on Synthetic and Medicinal Facets of 1,2,4-Triazolo[3,4-b][1,3,4]thiadiazine Scaffold 1,2,4-三唑[3,4-b][1,3,4]噻二嗪支架的合成及药用研究进展

IF 8.6 2区化学

Topics in Current Chemistry Pub Date : 2022-02-05 DOI: 10.1007/s41061-022-00365-x

Ranjana Aggarwal, Mona Hooda, Prince Kumar, Garima Sumran

{"title":"Vision on Synthetic and Medicinal Facets of 1,2,4-Triazolo[3,4-b][1,3,4]thiadiazine Scaffold","authors":"Ranjana Aggarwal, Mona Hooda, Prince Kumar, Garima Sumran","doi":"10.1007/s41061-022-00365-x","DOIUrl":"10.1007/s41061-022-00365-x","url":null,"abstract":"<div><p>The present review article strives to compile the latest synthetic approaches for the synthesis of triazolothiadiazine and its derivatives, along with their diverse pharmacological activities, viz. anticancer, antimicrobial, analgesic and anti-inflammatory, antioxidant, antiviral, enzyme inhibitors (carbonic anhydrase inhibitors, cholinesterase inhibitors, alkaline phosphatase inhibitors, anti-lipase activity, and aromatase inhibitors) and antitubercular agents. The review focuses particularly on the structure–activity relationship of biologically important 1,2,4-triazolo[3,4-<i>b</i>][1,3,4]thiadiazines, which have profound importance in drug design, discovery and development. In silico pharmacokinetic and molecular modeling studies have also been summarized. It is hoped that this review article will be of help to researchers engaged in the development of new biologically active entities for the rational design and development of new target-oriented 1,2,4-triazolo[3,4-<i>b</i>][1,3,4]thiadiazine-based drugs for the treatment of multifunctional diseases.</p><h3>Graphical Abstract</h3>\u0000 <figure><div><div><div><picture><source><img></source></picture></div></div></div></figure>\u0000 </div>","PeriodicalId":54344,"journal":{"name":"Topics in Current Chemistry","volume":"380 2","pages":""},"PeriodicalIF":8.6,"publicationDate":"2022-02-05","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://link.springer.com/content/pdf/10.1007/s41061-022-00365-x.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"4541970","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"化学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 6

Coupled- and Independent-Trajectory Approaches Based on the Exact Factorization Using the PyUNIxMD Package 基于PyUNIxMD包的精确分解的耦合和独立轨迹方法

IF 8.6 2区化学

Topics in Current Chemistry Pub Date : 2022-01-27 DOI: 10.1007/s41061-021-00361-7

Tae In Kim, Jong-Kwon Ha, Seung Kyu Min

引用次数: 3

Review on Amphiphilic Ionic Liquids as New Surfactants: From Fundamentals to Applications 两亲性离子液体作为新型表面活性剂的研究进展:从基础到应用

IF 8.6 2区化学

Topics in Current Chemistry Pub Date : 2021-11-29 DOI: 10.1007/s41061-021-00362-6

Mona Kharazi, Javad Saien, Simin Asadabadi

{"title":"Review on Amphiphilic Ionic Liquids as New Surfactants: From Fundamentals to Applications","authors":"Mona Kharazi, Javad Saien, Simin Asadabadi","doi":"10.1007/s41061-021-00362-6","DOIUrl":"10.1007/s41061-021-00362-6","url":null,"abstract":"<div><p>The demand for lowering interfacial tension (IFT) in different processes has persuaded researchers to use stable and resistant surfactants with low environmental impact. For this purpose, surface-active ionic liquids (SAILs) have attracted much attention owing to their good amphiphilic nature and prominent properties like recyclability and high performance under harsh conditions. This review initially explains how the IFT and critical micelle concentration of different systems vary in the presence of different SAILs with a variety of alkyl chain lengths, head groups, and counter anions. Towards this aim, some physicochemical properties of SAILs as well as the corresponding theoretical aspects of adsorption are considered. Then, recent advances in utilizing SAILs for reducing IFT of different chemical systems are surveyed. Relevantly, the role of important operating parameters of temperature, pH, presence of electrolytes, and the chemical nature of involved phases are adequately discussed. Further, an overview of different SAILs applications in stabilization, separation, and in petroleum industries is scrutinized. To allow better judgment, precise comparisons between different types of SAILs and conventional surfactants are provided. Finally, challenges and possible directions of future research on SAILs are highlighted.</p></div>","PeriodicalId":54344,"journal":{"name":"Topics in Current Chemistry","volume":"380 1","pages":""},"PeriodicalIF":8.6,"publicationDate":"2021-11-29","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://link.springer.com/content/pdf/10.1007/s41061-021-00362-6.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"5132499","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"化学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 21

Ensemble Density Functional Theory of Neutral and Charged Excitations 中性和带电激励的系综密度泛函理论

IF 8.6 2区化学

Topics in Current Chemistry Pub Date : 2021-11-26 DOI: 10.1007/s41061-021-00359-1

Filip Cernatic, Bruno Senjean, Vincent Robert, Emmanuel Fromager

{"title":"Ensemble Density Functional Theory of Neutral and Charged Excitations","authors":"Filip Cernatic, Bruno Senjean, Vincent Robert, Emmanuel Fromager","doi":"10.1007/s41061-021-00359-1","DOIUrl":"10.1007/s41061-021-00359-1","url":null,"abstract":"<div><p>Recent progress in the field of (time-independent) ensemble density-functional theory (DFT) for excited states are reviewed. Both Gross–Oliveira–Kohn (GOK) and <i>N</i>-centered ensemble formalisms, which are mathematically very similar and allow for an in-principle-exact description of neutral and charged electronic excitations, respectively, are discussed. Key exact results, for example, the equivalence between the infamous derivative discontinuity problem and the description of weight dependencies in the ensemble exchange-correlation density functional, are highlighted. The variational evaluation of orbital-dependent ensemble Hartree-exchange (Hx) energies is discussed in detail. We show in passing that state-averaging individual exact Hx energies can lead to severe (although solvable) <i>v</i>-representability issues. Finally, we explore the possibility of using the concept of density-driven correlation, which has been introduced recently and does not exist in regular ground-state DFT, for improving state-of-the-art correlation density-functional approximations for ensembles. The present review reflects the efforts of a growing community to turn ensemble DFT into a rigorous and reliable low-cost computational method for excited states. We hope that, in the near future, this contribution will stimulate new formal and practical developments in the field.</p></div>","PeriodicalId":54344,"journal":{"name":"Topics in Current Chemistry","volume":"380 1","pages":""},"PeriodicalIF":8.6,"publicationDate":"2021-11-26","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"5019932","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"化学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 10

Alginate-Based Smart Materials and Their Application: Recent Advances and Perspectives 海藻酸盐基智能材料及其应用:最新进展与展望

IF 8.6 2区化学

Topics in Current Chemistry Pub Date : 2021-11-23 DOI: 10.1007/s41061-021-00360-8

Chandan Maity, Nikita Das

{"title":"Alginate-Based Smart Materials and Their Application: Recent Advances and Perspectives","authors":"Chandan Maity, Nikita Das","doi":"10.1007/s41061-021-00360-8","DOIUrl":"10.1007/s41061-021-00360-8","url":null,"abstract":"<div><p>Nature produces materials using available molecular building blocks following a bottom-up approach. These materials are formed with great precision and flexibility in a controlled manner. This approach offers the inspiration for manufacturing new artificial materials and devices. Synthetic artificial materials can find many important applications ranging from personalized therapeutics to solutions for environmental problems. Among these materials, responsive synthetic materials are capable of changing their structure and/or properties in response to external stimuli, and hence are termed “smart” materials. Herein, this review focuses on alginate-based smart materials and their stimuli-responsive preparation, fragmentation, and applications in diverse fields from drug delivery and tissue engineering to water purification and environmental remediation. In the first part of this report, we review stimuli-induced preparation of alginate-based materials. Stimuli-triggered decomposition of alginate materials in a controlled fashion is documented in the second part, followed by the application of smart alginate materials in diverse fields. Because of their biocompatibility, easy accessibility, and simple techniques of material formation, alginates can provide solutions for several present and future problems of humankind. However, new research is needed for novel alginate-based materials with new functionalities and well-defined properties for targeted applications.</p></div>","PeriodicalId":54344,"journal":{"name":"Topics in Current Chemistry","volume":"380 1","pages":""},"PeriodicalIF":8.6,"publicationDate":"2021-11-23","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://link.springer.com/content/pdf/10.1007/s41061-021-00360-8.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"4913491","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"化学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 27