Glycopolymer-Based Materials: Synthesis, Properties, and Biosensing Applications

IF 7.1 2区化学 Q1 CHEMISTRY, MULTIDISCIPLINARY

Topics in Current Chemistry Pub Date : 2022-08-11 DOI:10.1007/s41061-022-00395-5

Mohammad R. Thalji, Amal Amin Ibrahim, Kwok Feng Chong, Alexander V. Soldatov, Gomaa A. M. Ali

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引用次数: 7

Abstract

Glycopolymer materials have emerged as a significant biopolymer class that has piqued the scientific community's attention due to their potential applications. Recently, they have been found to be a unique synthetic biomaterial; glycopolymer materials have also been used for various applications, including direct therapeutic methods, medical adhesives, drug/gene delivery systems, and biosensor applications. Therefore, for the next stage of biomaterial research, it is essential to understand current breakthroughs in glycopolymer-based materials research. This review discusses the most widely utilized synthetic methodologies for glycopolymer-based materials, their properties based on structure–function interactions, and the significance of these materials in biosensing applications, among other topics. When creating glycopolymer materials, contemporary polymerization methods allow precise control over molecular weight, molecular weight distribution, chemical activity, and polymer architecture. This review concludes with a discussion of the challenges and complexities of glycopolymer-based biosensors, in addition to their potential applications in the future.

Graphical Abstract

Abstract Image

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基于糖基共聚物的材料:合成、性能和生物传感应用

由于其潜在的应用前景，甘共聚物材料已经成为一类重要的生物聚合物，引起了科学界的关注。最近，它们被发现是一种独特的合成生物材料;gly共聚物材料也被用于各种应用，包括直接治疗方法、医疗粘合剂、药物/基因传递系统和生物传感器应用。因此，对于下一阶段的生物材料研究，了解当前基于糖共聚物的材料研究的突破是至关重要的。这篇综述讨论了最广泛使用的基于糖共聚物的材料的合成方法，它们基于结构-功能相互作用的特性，以及这些材料在生物传感应用中的意义，以及其他主题。当创建糖共聚物材料时，当代聚合方法可以精确控制分子量，分子量分布，化学活性和聚合物结构。本文最后讨论了基于糖共聚物的生物传感器的挑战和复杂性，以及它们在未来的潜在应用。图形抽象

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来源期刊

Topics in Current Chemistry Chemistry-General Chemistry

CiteScore

13.70

自引率

1.20%

发文量

期刊介绍： Topics in Current Chemistry is a journal that presents critical reviews of present and future trends in modern chemical research. It covers all areas of chemical science, including interactions with related disciplines like biology, medicine, physics, and materials science. The articles in this journal are organized into thematic collections, offering a comprehensive perspective on emerging research to non-specialist readers in academia or industry. Each review article focuses on one aspect of the topic and provides a critical survey, placing it in the context of the collection. Selected examples highlight significant developments from the past 5 to 10 years. Instead of providing an exhaustive summary or extensive data, the articles concentrate on methodological thinking. This approach allows non-specialist readers to understand the information fully and presents the potential prospects for future developments.