{"title":"Relationship between glucagon-like peptide-1 receptor agonist use and incidence of trigger finger in patients with type 2 diabetes","authors":"Kyle Stump , Henry Morar , Alec Talsania , Dianly Centeno , Lasya Sethi , Bradley Wiekrykas","doi":"10.1016/j.hansur.2026.102589","DOIUrl":"10.1016/j.hansur.2026.102589","url":null,"abstract":"<div><h3>Purpose</h3><div>The relationship between glucagon-like peptide-1 receptor agonist (GLP-1 RA) use and trigger finger (TF) remains unknown. This study aims to compare rates of TF, TF release, and complications of TF release between diabetic patients with and without a history of GLP-1 RA use.</div></div><div><h3>Methods</h3><div>This study utilized the TriNetX database to identify adult patients with Type II diabetes mellitus. The primary analysis included patients with and without a history of GLP-1 RA use. The secondary analysis included patients with a history of TF separated by the presence or absence of GLP-1 RA use, respectively. The tertiary analysis included patients with and without a history of GLP-1 RA use within the 6 months prior to TF release. Cohorts were propensity-matched 1:1 based on demographic characteristics and medical comorbidities. The primary outcome was the incidence of TF; the secondary outcome was the incidence of TF release. Tertiary outcomes included postoperative complications within 90 days of surgery.</div></div><div><h3>Results</h3><div>GLP-1 RA use was associated with a significant reduction in the prevalence of trigger finger. In contrast, GLP-1 RA users demonstrated a higher prevalence of TF release and similar rates of surgical site infection, joint stiffness, wound dehiscence, and abscess irrigation and debridement following operative release.</div></div><div><h3>Conclusions</h3><div>Glucagon-like peptide-1 receptor agonist use in patients with type 2 diabetes mellitus is associated with a reduction in the prevalence of trigger finger without an elevation in complication risk following surgical release. Interestingly, we also observed increased prevalence of trigger finger release among glucagon-like peptide-1 receptor agonist users.</div></div>","PeriodicalId":54301,"journal":{"name":"Hand Surgery & Rehabilitation","volume":"45 2","pages":"Article 102589"},"PeriodicalIF":1.0,"publicationDate":"2026-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"146097750","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Kyle Wallace , Charles Furlong , John Etchart , Curtis M. Henn
{"title":"Neuralgic amyotrophy: Incidence, specialty of diagnosing clinician, and delays in treatment","authors":"Kyle Wallace , Charles Furlong , John Etchart , Curtis M. Henn","doi":"10.1016/j.hansur.2026.102591","DOIUrl":"10.1016/j.hansur.2026.102591","url":null,"abstract":"<div><h3>Purpose</h3><div>This study sought to determine the incidence of Neuralgic Amyotrophy (NA) in the United States of America’s health system, most common presenting symptoms, time from symptom onset and time from initial presentation to diagnosis, number and specialty of clinicians seen prior to diagnosis, and specialty of diagnosing clinician.</div></div><div><h3>Methods</h3><div>A retrospective chart review study was conducted to identify all patients diagnosed with ICD-10 G54.5 from September 1, 2016–December 31, 2023.</div></div><div><h3>Results</h3><div>153 patients with NA diagnoses from 2016 to 2023 were included. The average incidence of NA in the United States of America’s healthcare system was 1.77/100,000 per year. The most common chief concern upon presentation was shoulder pain, (<em>n</em> = 57, 37.2%) and the most common secondary or tertiary concern was shoulder weakness (<em>n</em> = 41, 26.7%). Average time from symptom onset to diagnosis was 101.3 days (SD = 155.4; median = 51 days), and from initial presentation to diagnosis was 78.1 days (SD = 145.6; median = 28 days). Sixty-three patients (41.2%) presented to one other clinician with similar symptoms prior to diagnosis, 37 (24.2%) saw two clinicians, 16 (10.5%) saw three, and 7 (4.6%) saw four or more clinicians. Patients most often initially presented to a family medicine, primary care, or urgent care clinician (<em>n</em> = 61, 39.9%). The most common specialties of diagnosing clinicians were orthopaedic surgery (100 diagnoses, 65.4%), neurology (23 diagnoses, 15%) and neurosurgery (15 diagnoses, 10%).</div></div><div><h3>Conclusion</h3><div>Diagnosis of neuralgic amyotrophy is historically rare, but the incidence may be higher than previously thought. Neuralgic amyotrophy is a debilitating disorder that is often initially unrecognized, ultimately leading to a months-long delay in diagnosis. Over 80% of patients were seen by at least one other clinician before diagnosis, and orthopaedic clinicians were most likely to make the diagnosis.</div></div><div><h3>Clinical relevance</h3><div>Maintaining a high clinical suspicion while recognizing the common presenting symptoms along with onset and evolution of symptoms would help facilitate timely referral to specialists trained in identifying and managing neuralgic amyotrophy, prevent unnecessary and unproductive appointments preceding the diagnosis, and allow earlier initiation of treatment.</div></div><div><h3>Level of evidence</h3><div>Diagnostic Type IV.</div></div>","PeriodicalId":54301,"journal":{"name":"Hand Surgery & Rehabilitation","volume":"45 2","pages":"Article 102591"},"PeriodicalIF":1.0,"publicationDate":"2026-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"146133783","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Comment on “Radial nerve at Frohse’s arcade: A new technique of release under total ultrasound guidance. First experience”","authors":"Ruben Dukan , Remy Pichard","doi":"10.1016/j.hansur.2025.102301","DOIUrl":"10.1016/j.hansur.2025.102301","url":null,"abstract":"","PeriodicalId":54301,"journal":{"name":"Hand Surgery & Rehabilitation","volume":"45 2","pages":"Article 102301"},"PeriodicalIF":1.0,"publicationDate":"2026-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147319136","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Ron Gurel, Ofer Mali, Shai Factor, Yishai Rosenblatt, Tamir Pritsch
{"title":"Outcomes after carpal tunnel release in patients with fibromyalgia: A retrospective matched cohort study","authors":"Ron Gurel, Ofer Mali, Shai Factor, Yishai Rosenblatt, Tamir Pritsch","doi":"10.1016/j.hansur.2026.102637","DOIUrl":"10.1016/j.hansur.2026.102637","url":null,"abstract":"<div><h3>Background</h3><div>Fibromyalgia is a centralized pain disorder associated with inferior postoperative outcomes across multiple surgical disciplines. Its impact on outcomes following carpal tunnel release (CTR) was yet to be studied. This study compared postoperative outcomes after CTR in patients with fibromyalgia and matched controls.</div></div><div><h3>Methods</h3><div>A retrospective matched cohort study was performed including adult patients who underwent open CTR between 2010 and 2024. Patients with fibromyalgia were matched 1:1 with controls without fibromyalgia based on age, sex, hand dominance, preoperative CTS-6 score, preoperative pain intensity, and follow-up duration. Outcomes included postoperative Numeric Pain Rating Scale (NPRS) scores, Boston Carpal Tunnel Questionnaire Symptom Severity Scale (BCTQ-SSS) and Functional Status Scale (BCTQ-FSS), early postoperative pain, long-term pain (NPRS ≥ 5), pain improvement, and patient satisfaction.</div></div><div><h3>Results</h3><div>Twenty-seven patients with fibromyalgia were matched to 27 controls. Baseline characteristics did not differ between the groups. Patients with fibromyalgia demonstrated higher postoperative pain (NPRS 3.6 vs 1.8; p = 0.02), worse symptom severity and function (BCTQ-SSS 2.2 vs 1.5; p = 0.004; BCTQ-FSS 2.8 vs 1.8; p = 0.002), and higher rates of both a painful early postoperative period (44.4% vs 7.4%; p = 0.002) and residual long-term pain (48% vs 15%; p = 0.008). Despite this, both groups experienced significant postoperative pain reduction (p < 0.001), with no significant difference in pain improvement rate and magnitude or patient satisfaction. The magnitude of within-group postoperative pain improvement in both cohorts exceeded the minimal clinically important difference.</div></div><div><h3>Conclusion</h3><div>Fibromyalgia is associated with higher postoperative pain and worse patient-reported outcomes after CTR but does not preclude clinically meaningful improvement. CTR remains effective in patients with fibromyalgia, although surgeons should counsel patients regarding a potentially more painful postoperative course and higher rates of residual symptoms.</div></div>","PeriodicalId":54301,"journal":{"name":"Hand Surgery & Rehabilitation","volume":"45 2","pages":"Article 102637"},"PeriodicalIF":1.0,"publicationDate":"2026-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147391256","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Chloe R. Wong , Shawn Khan , Ryan Paul , Kevin J. Zuo , Jonathan Persitz
{"title":"Dorsal wrist capsular impingement: a systematic review of clinical presentation, imaging findings, arthroscopic characteristics, and treatment outcomes","authors":"Chloe R. Wong , Shawn Khan , Ryan Paul , Kevin J. Zuo , Jonathan Persitz","doi":"10.1016/j.hansur.2026.102639","DOIUrl":"10.1016/j.hansur.2026.102639","url":null,"abstract":"<div><h3>Purpose</h3><div>To systematically review the clinical presentation, imaging findings, arthroscopic characteristics, and treatment outcomes of dorsal wrist capsular impingement, a distinct cause of chronic dorsal wrist pain.</div></div><div><h3>Methods</h3><div>A review was performed in accordance with PRISMA guidelines. MEDLINE, EMBASE, CENTRAL, and CINAHL were searched from inception to January 11, 2026. Eligible studies included patients diagnosed with dorsal wrist capsular impingement. Data were synthesized narratively.</div></div><div><h3>Results</h3><div>Six studies comprising 231 patients (233 wrists) met inclusion criteria. Age ranged from 27 to 42 years, and 53% of patients were male (122/231). Follow-up ranged from 6 to 42 months. All patients presented with dorsal-central wrist pain (231/231, 100%). Extension-provoked pain was reported in 177 wrists (77%) and in all patients in the five studies describing this symptom. MRI findings were inconsistently reported and demonstrated limited correlation with intraoperative pathology. Across four studies, hypertrophied or redundant dorsal capsular tissue interposed within the radiocarpal joint was identified in all evaluated wrists (66/66, 100%). Following arthroscopic debridement, most treated wrists demonstrated postoperative pain reduction. QuickDASH scores improved across studies, decreasing from approximately 33–49 preoperatively to 4.8–17 at 3–12 months postoperatively. Recurrence was uncommon (2 wrists, 1%), and complications were rare.</div></div><div><h3>Conclusion</h3><div>Dorsal wrist capsular impingement presents with chronic, extension-provoked dorsal-central wrist pain, often despite nondiagnostic imaging. Arthroscopy may aid diagnosis and management, with reported intraoperative findings and symptomatic improvement in selected patients. Current evidence is limited to small retrospective studies, and prospective research is needed to better define diagnostic criteria and outcomes.</div></div>","PeriodicalId":54301,"journal":{"name":"Hand Surgery & Rehabilitation","volume":"45 2","pages":"Article 102639"},"PeriodicalIF":1.0,"publicationDate":"2026-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147470614","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Joseph Manchon , Christophe Chantelot , Éric Senneville , Marc Saab
{"title":"Risk factors for surgical revision and functional outcomes in 121 Pasteurella hand infections","authors":"Joseph Manchon , Christophe Chantelot , Éric Senneville , Marc Saab","doi":"10.1016/j.hansur.2026.102625","DOIUrl":"10.1016/j.hansur.2026.102625","url":null,"abstract":"<div><h3>Introduction</h3><div><em>Pasteurella</em> spp. are frequently implicated in animal-related hand infections, often presenting with severe local symptoms. Given their frequency and potential severity, we conducted a retrospective study to identify the incidence and risk factors for surgical revision and to evaluate long-term functional outcomes.</div></div><div><h3>Methods</h3><div>This single-center retrospective analytical study included patients operated on in a hand emergency center between November 2011 and June 2024. Eligible patients had deep structural involvement of the hand and intraoperative bacteriological samples positive for <em>Pasteurella</em> spp. Functional outcomes were assessed by telephone or videoconference. Univariate analysis was performed using chi-square or Fisher’s exact tests, with odds ratios (ORs) calculated for each risk factor.</div></div><div><h3>Results</h3><div>121 patients were included. The median interval between surgery and follow-up was 21 months (range 2–152). Fifteen patients (12.4%) required surgical revision. Significant risk factors for revision were diabetes (OR 3.9), septic arthritis (OR 4.0), initial management delay >72 h (OR 4.4), and age 45–65 years (OR 4.6). Functional assessment showed a significant reduction in total active motion of the long fingers and thumb compared with the contralateral side, while the Kapandji score was not significantly affected. Fourteen percent of patients reported mechanical pain and 26% neuropathic pain, although all resumed their usual activities satisfactorily.</div></div><div><h3>Conclusion</h3><div>This study identified four risk factors for emergency surgical revision in <em>Pasteurella</em> spp. hand infections. Functional outcomes demonstrated significant reductions in total active motion of the fingers, with a notable prevalence of residual neuropathic (26.4%) and mechanical pain (14%). Tailoring management to these factors may improve outcomes, pending confirmation by multivariate analysis.</div></div>","PeriodicalId":54301,"journal":{"name":"Hand Surgery & Rehabilitation","volume":"45 2","pages":"Article 102625"},"PeriodicalIF":1.0,"publicationDate":"2026-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"146260585","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Ankit Hirpara , Ansh Shah , Emma Smolev , Kira L. Smith , Logan M. Good , Ian Christman , Kevin J. Malone , Matthew V. Abola
{"title":"Impact of non-tobacco nicotine dependence on outcomes following carpal tunnel release: A retrospective cohort study","authors":"Ankit Hirpara , Ansh Shah , Emma Smolev , Kira L. Smith , Logan M. Good , Ian Christman , Kevin J. Malone , Matthew V. Abola","doi":"10.1016/j.hansur.2026.102588","DOIUrl":"10.1016/j.hansur.2026.102588","url":null,"abstract":"<div><h3>Introduction</h3><div>Non-tobacco nicotine dependence (NTND) from products like e-cigarettes and pouches is rapidly rising. Studies have shown that tobacco can negatively impact outcomes following carpal tunnel release (CTR), but literature focusing specifically on NTND is sparse. As such, the purpose of this study was to compare outcomes following CTR between patients with versus without a history of NTND.</div></div><div><h3>Methods</h3><div>The TriNetX database was queried to identify patients over 18 years old who underwent primary CTR. Patients were stratified based on their history of NTND. Cohorts underwent propensity score matching in a 1:1 ratio using demographics, medical comorbidities, and substance use. The following outcomes were collected: 1) post-operative complications, surgical complications, and healthcare utilization within 90 days, 2) opioid use within 2 years, and 3) revision CTR within 2 years.</div></div><div><h3>Results</h3><div>Within 90 days, patients with NTND (<em>n</em> = 9811), compared to those without (<em>n</em> = 9811), had significantly higher rates of healthcare utilization, including emergency department visits (<em>p</em> < 0.001), and post-operative complications, like pneumonia (OR: 1.372, <em>p</em> = 0.036) and wound complications (OR: 1.501, <em>p</em> = 0.005). There were no differences in surgical complications. More patients with NTND were prescribed opioids at all time points within 2 years of CTR (all <em>p</em> < 0.001). There were no differences in revision surgery rates.</div></div><div><h3>Conclusion</h3><div>Non-tobacco nicotine dependence is associated with higher rates of healthcare utilization, medical complications, and opioid use following carpal tunnel release. Increased clinical awareness, targeted patient counseling, and pre-operative optimization may be warranted for this growing population.</div></div>","PeriodicalId":54301,"journal":{"name":"Hand Surgery & Rehabilitation","volume":"45 2","pages":"Article 102588"},"PeriodicalIF":1.0,"publicationDate":"2026-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"146097768","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Soo Min Cha , Seung Hoo Lee , In Ho Ga , Yong Hwan Kim , Jin Seok Oh
{"title":"Sequential bilateral ulnar shortening osteotomy and arthroscopic triangular fibrocartilage complex foveal repair","authors":"Soo Min Cha , Seung Hoo Lee , In Ho Ga , Yong Hwan Kim , Jin Seok Oh","doi":"10.1016/j.hansur.2026.102598","DOIUrl":"10.1016/j.hansur.2026.102598","url":null,"abstract":"<div><h3>Introduction</h3><div>The purpose of this study was to retrospectively analyze the clinical features and surgical outcomes of a distinct subgroup of patients who underwent sequential bilateral ulnar shortening osteotomy with arthroscopic triangular fibrocartilage complex (TFCC) foveal repair for ulnar impaction syndrome (UIS) associated with distal radioulnar joint (DRUJ) instability, with a particular focus on the development of contralateral symptoms following initial unilateral surgery.</div></div><div><h3>Methods</h3><div>A retrospective review was conducted of 26 patients who underwent bilateral ulnar shortening osteotomy with TFCC foveal repair between 2015 and 2022, with at least 2 years of follow-up for each wrist. The inclusion criteria were radiologically positive ulnar variance (≥3 mm), arthroscopic evidence of lunate chondromalacia, definitive foveal TFCC detachment, and DRUJ instability in both wrists.</div></div><div><h3>Results</h3><div>In 88% of the patients, the initial surgery was performed on the dominant side with the mean age of 34.08 years. All preoperative statuses improved at the final follow-up. Subsequent surgeries were conducted on the contralateral side with a mean interval of 15.7 months. At follow-up, significant improvement from the preoperative status was observed, while the contralateral surgery group showed less preoperative deterioration in grip strength, VAS, MMWS, and DASH scores than at the initial surgery. However, both groups showed comparable improvements in all outcome measures at the final follow-up.</div></div><div><h3>Conclusion</h3><div>Sequential bilateral ulnar shortening osteotomy with TFCC foveal repair yielded consistently favorable outcomes, regardless of surgical side or baseline functional deficit. The interval between surgeries and the absence of a history of trauma suggest that contralateral pathology may develop in the context of degenerative changes, potentially influenced by compensatory overuse during postoperative recovery.</div></div><div><h3>Level of evidence</h3><div>Level IV, retrospective case series.</div></div>","PeriodicalId":54301,"journal":{"name":"Hand Surgery & Rehabilitation","volume":"45 2","pages":"Article 102598"},"PeriodicalIF":1.0,"publicationDate":"2026-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"146195469","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"The biomechanical role of oedema in the development of the “negative hand” posture","authors":"Paolo Boccolari , Pasquale Arcuri , Roberto Tedeschi , Danilo Donati","doi":"10.1016/j.hansur.2025.102528","DOIUrl":"10.1016/j.hansur.2025.102528","url":null,"abstract":"","PeriodicalId":54301,"journal":{"name":"Hand Surgery & Rehabilitation","volume":"45 2","pages":"Article 102528"},"PeriodicalIF":1.0,"publicationDate":"2026-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147636733","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}