Current Medical Imaging Reviews最新文献

{"title":"Development of a Radiomic-clinical Nomogram for Prediction of Survival in Patients with Nasal Extranodal Natural Killer/T-cell Lymphoma.","authors":"Limin Chen, Zhao Wang, Xiaojie Fang, Mingjie Yu, Haimei Ye, Lujun Han, Ying Tian, Chengcheng Guo, Huang He","doi":"10.2174/0115734056319914250605053257","DOIUrl":"https://doi.org/10.2174/0115734056319914250605053257","url":null,"abstract":"<p><strong>Introduction: </strong>An accurate and reliable prognostic model for Nasal Extranodal Natural Killer/T-cell Lymphoma (ENKTL) is critical for survival outcomes and personalized therapy. Currently, there is no Magnetic Resonance Imaging (MRI)- based radiomics analysis in the prognosis model for nasal ENKTL patients.</p><p><strong>Objective: </strong>We aim to explore the value of MRI-based radiomics signature in the prognosis of patients with nasal ENKTL.</p><p><strong>Methods: </strong>A total of 159 nasal ENKTL patients were enrolled and divided into a training cohort (n=81) and a validation cohort (n=78) randomly. Radiomics features from pretreatment MRI examination were extracted, respectively. Then two-sample t-test and Least Absolute Shrinkage and Selection Operator (LASSO) regression were used to select the radiomics signatures and establish the Rad-score. Univariate and multivariate Cox proportional hazards regression models were used to investigate the prognostic value of baseline clinical features and establish clinical models. A radiomics nomogram based on the Rad-score and clinical features was constructed to predict Overall Survival (OS). The predictive efficacy of the three models was evaluated in two cohorts.</p><p><strong>Results: </strong>A total of 1,345 features were extracted from T2-weighted (T2-w) and Contrast-enhanced T1-weighted (CET1-w) images, respectively, and 1,037 features with Intraclass Correlation Coefficient (ICC) >0.7 were selected. Ultimately, 20 features were chosen to construct the Rad-score, which showed a significant association with OS. The C-indexes of the Rad-score were 0.733 (95% confidence interval [CI]: 0.645 to 0.816) and 0.824 (95% CI: 0.766-0.882), respectively, in training and validation cohorts. Through the univariate and multivariate analyses, three independent risk factors for OS were identified: Rad-score (HR: 10.962, 95% CI: 3.417-35.167, P <0.001), lactate dehydrogenase (LDH) level (HR: 3.009, 95% CI: 1.128-8.510, P = 0.028) and distant lymph-node involvement (HR: 2.966, 95% CI: 1.015-8.664, P = 0.047). Patients with distal lymph node involvement and LDH level before treatment were included in the clinical model, which achieved a C-index of 0.707 (95% CI: 0.600-0.814) in the training cohort and 0.635 (95% CI: 0.527-0.743) in the validation cohort. We integrated the Rad-score and clinical variables to establish a radiomics nomogram, which exhibited a satisfactory prediction performance with the C-indexes of 0.849(95% CI: 0.781-0.917) and 0.931(95% CI: 0.882-0.980) in two cohorts, respectively. The radiomics nomogram was more accurate in predicting OS in patients with nasal ENKTL than the other two models. Based on the radiomics nomogram, patients were categorized into low-risk and high-risk groups in two cohorts (P all < 0.05). The high-risk group defined by this nomogram exhibited a shorter OS.</p><p><strong>Conclusion: </strong>The Rad-score was significantly correlated with OS for ","PeriodicalId":54215,"journal":{"name":"Current Medical Imaging Reviews","volume":" ","pages":""},"PeriodicalIF":1.1,"publicationDate":"2025-06-19","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144477846","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Navigating the Diagnostic Maze: A Case Report and Narrative Review of Reversible Cerebral Vasoconstriction Syndrome.","authors":"Xuefan Yao, Yuzhe Li, Aini He, Benke Zhao, Wei Sun, Xiao Wu, Haiqing Song","doi":"10.2174/0115734056366051250604054327","DOIUrl":"10.2174/0115734056366051250604054327","url":null,"abstract":"<p><strong>Introduction: </strong>Reversible cerebral vasoconstriction syndrome (RCVS) is a condition characterized by thunderclap headaches, which are sudden and severe headaches that peak within a few seconds. These headaches present diagnostic difficulties due to their diversity and low specificity, often leading to misdiagnoses and patient dissatisfaction.</p><p><strong>Case presentation: </strong>We present the case of a 52-year-old woman with a 10-day history of recurrent thunderclap headaches. Initial imaging revealed no abnormalities, but she experienced further episodes of thunderclap headaches during hospitalization. Subsequent neurovascular imaging revealed multiple intracranial stenoses with a \"string of beads\" appearance, confirming the diagnosis of reversible cerebral vasoconstriction syndrome. She was treated with nimodipine, and most symptoms had resolved upon discharge, with no recurrence of headache reported during a 3-month follow-up.</p><p><strong>Discussion: </strong>Prior reviews on reversible cerebral vasoconstriction syndrome predominantly emphasized isolated symptoms or advanced neuroimaging findings, offering limited applicability in primary care services. More attention should be given to identifying clinical manifestations warranting heightened reversible cerebral vasoconstriction syndrome suspicion.</p><p><strong>Conclusion: </strong>Early recognition of reversible cerebral vasoconstriction syndrome counts in primary care services. We proposed a revised diagnostic routine that begins with clinical suspicion prompted by typical manifestations, like recurrent thunderclap headaches, female sex, and specific triggers, and recommends advanced neurovascular imaging when accessible. Extreme headache severity or deviation from prior migraine patterns should raise suspicion for reversible cerebral vasoconstriction syndrome, while diagnostic consideration should still remain in patients with transient neurological deficits, seizures, or cerebrovascular events.</p>","PeriodicalId":54215,"journal":{"name":"Current Medical Imaging Reviews","volume":" ","pages":""},"PeriodicalIF":1.1,"publicationDate":"2025-06-17","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144334420","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Research of imaging in left Atrium: A Bibliometric Analysis.","authors":"Can Cui, Jiang-Hua Zhu, Ya-Hong Tao, Zhen-Yi Zhao, Yun Peng, Minjing Zuo","doi":"10.2174/0115734056356151250604021748","DOIUrl":"https://doi.org/10.2174/0115734056356151250604021748","url":null,"abstract":"<p><strong>Background: </strong>The evaluation of the left atrial (LA) by imaging is becoming increasingly essential due to its significant role in numerous diseases. This study aimed to analyze and summarize research on LA imaging in the past 20 years through bibliometric analysis and offer insights into future research prospects.</p><p><strong>Methods: </strong>The Web of Science (WOS) core collection database was retrieved for literature in LA imaging research from 2004 to 2023. Subsequently, the literature was processed and visualized by the VOSviewer and CiteSpace. VOSviewer was used to create cooperation networks for countries/regions and institutions. CiteSpace was used to analyze burst keywords in citation analysis.</p><p><strong>Results: </strong>A total of 3664 articles published in this field between January 2004 and December 2023 were analyzed. The number of published articles is increasing year by year. The USA contributed the most articles (1072). Hugh Calkins (44) was the most productive author with the highest publications.</p><p><strong>Conclusion: </strong>Over the past 20 years, research on LA imaging has grown rapidly. The results of the present study provide insights into the field's status and indicate the research hotspots. In recent years, research on left atrial appendage occlusion (LAAO) and LA strain has been notably focused, which is expected to remain a prominent topic in future research.</p>","PeriodicalId":54215,"journal":{"name":"Current Medical Imaging Reviews","volume":" ","pages":""},"PeriodicalIF":1.1,"publicationDate":"2025-06-10","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144287126","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"A Case Report of Cor Triatriatum Sinister (CTS) in an Asymptomatic Adult with Chronic Adhesive Pericarditis.","authors":"Yuan-Teng Hsu, Chee-Siong Lee, Jui-Sheng Hsu, Che-Lun Hsu, Ding-Kwo Wu","doi":"10.2174/0115734056383803250523070650","DOIUrl":"https://doi.org/10.2174/0115734056383803250523070650","url":null,"abstract":"<p><strong>Introduction: </strong>Cor Triatriatum Sinister (CTS) is a rare congenital anomaly, accounting for 0.1%- 0.4% of congenital heart diseases. While often diagnosed and treated in infancy, some cases remain asymptomatic until adulthood due to large fenestrations. This report presents a unique case of CTS in an adult coexisting with chronic adhesive pericarditis, which may have contributed to chronic atrial dilatation, a condition not previously documented.</p><p><strong>Case presentation: </strong>A 60-year-old asymptomatic Taiwanese male underwent a routine medical examination. Coronary computed tomography angiography revealed a fenestrated septum dividing the left atrium, consistent with CTS. Virtual endoscopy confirmed two wide fenestrations. Notably, chronic adhesive pericarditis, evidenced by curvilinear calcifications, was diagnosed. This condition likely exacerbated the hemodynamic impact of CTS, contributing to left atrial dilation and atrial fibrillation. Atrial fibrillation was identified, and the patient was treated with an anticoagulant for stroke prevention.</p><p><strong>Conclusion: </strong>This is the first reported case of CTS coexisting with chronic adhesive pericarditis. Advanced imaging modalities, including cardiac computed tomography, angiography, and virtual endoscopy, are crucial for diagnosis and anatomical evaluation. Chronic adhesive pericarditis may amplify the effects of CTS, leading to complications, including atrial fibrillation. Anticoagulation is essential for stroke prevention in such cases.</p>","PeriodicalId":54215,"journal":{"name":"Current Medical Imaging Reviews","volume":" ","pages":""},"PeriodicalIF":1.1,"publicationDate":"2025-06-03","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144217525","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"An Unusual Occurrence of Synchronous Squamous Cell Carcinoma and Invasive Ductal Carcinoma in the Ipsilateral Breast: A Case Report.","authors":"Seoyun Choi, Eun Jung Choi, Bo Ram Kim, Kyoung Min Kim","doi":"10.2174/0115734056373786250527105407","DOIUrl":"https://doi.org/10.2174/0115734056373786250527105407","url":null,"abstract":"<p><strong>Background: </strong>The synchronous occurrence of primary pure squamous cell carcinoma (SCC) and invasive ductal carcinoma (IDC) of the breast is rare. Accurate identification of synchronous primary malignancies is crucial because their prognosis and treatment differ significantly from recurrent diseases. Herein, we present an unusual case highlighting the synchronous development of primary SCC and IDC in the ipsilateral breast.</p><p><strong>Case report: </strong>A 48-year-old woman presented with a palpable mass in her right breast. Preoperative dynamic contrast-enhanced magnetic resonance imaging (DCE-MRI) demonstrated an irregularly shaped mass with internal rim enhancement. Surgical resection confirmed IDC of nuclear grade 3 with a high proliferation index (Ki-67: 70%), and the patient underwent adjuvant chemotherapy without radiation. Five months postoperation, a chest computed tomography (CT) revealed a new round-shaped lesion with rim enhancement and relatively circumscribed margins near the previous operation site. Breast ultrasound additionally identified a complex cystic and solid mass with an echogenic rind and increased vascularity. Following total resection, a pure squamous cell carcinoma with prominent keratinization was confirmed.</p><p><strong>Conclusion: </strong>Accurate and early diagnosis of synchronous multiple primary malignancies from recurrence of the primary tumor is critical for improving prognosis by establishing an appropriate treatment and follow-up plan. Recognizing complex cystic and solid masses with relatively circumscribed margins on radiological imaging can assist clinicians in identifying and managing rare cases where IDC and SCC coexist or appear sequentially within a short period.</p>","PeriodicalId":54215,"journal":{"name":"Current Medical Imaging Reviews","volume":" ","pages":""},"PeriodicalIF":1.1,"publicationDate":"2025-06-03","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144217526","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"CT Quantitative Analysis in Evaluating Type 2 Diabetes Mellitus Complicated with Interstitial Lung Abnormalities.","authors":"Li Zhang, Qiu-Ju Fan, Shan Dang, Dong Han, Min Zhang, Shu-Guang Yan, Xiao-Kun Xin, Nan Yu","doi":"10.2174/0115734056343395250526140343","DOIUrl":"https://doi.org/10.2174/0115734056343395250526140343","url":null,"abstract":"<p><strong>Background: </strong>Type 2 diabetes mellitus (T2DM) complicated with interstitial lung abnormalities (ILAs) is often overlooked and can progress to severe diabetesinduced pulmonary fibrosis (DiPF). Therefore, early diagnosis of T2DM complicated with ILAs is crucial. Chest computed tomography (CT) is an important method for diagnosing T2DM complicated with ILAs. Quantitative computed tomography (QCT) is more objective and accurate than visual assessment on CT. However, there are currently limited studies on T2DM complicated with ILAs based on quantitative CT.</p><p><strong>Objective: </strong>This study aimed to explore the utility of quantitative computed tomography for early detection of lung injury in individuals with T2DM by examining CT-derived metrics in T2DM complicated with ILAs.</p><p><strong>Methods: </strong>We collected data from 135 T2DM complicated with ILAs on chest CT scans retrospectively, alongside 135 non-diabetic controls with normal CT findings. Employing digital lung software, chest CT images were processed to extract quantitative parameters: total lung volume (TLV), emphysema index (LAA-950%, the percentage of lung area with attenuation < -950 Hu to total lung volume), pulmonary fibrosis index (LAA-700~-200%, the percentage of lung area with attenuation from -700Hu to -200 Hu to the total lung volume), and pulmonary peripheral vascular index (ratio TAV/TNV, the number of blood vessels TNV, the cross-sectional area of blood vessels TAV). Statistical comparisons between groups utilized Mann-Whitney U or t-tests. Correlations between Hemoglobin A1c (HbA1c) levels and CT parameters were assessed via Pearson or Spearman correlations. Parameters showing statistical significance were further examined through receiver operating characteristic (ROC) analysis.</p><p><strong>Results: </strong>The T2DM-ILAs cohort displayed a significantly higher LAA-700~-200% compared to controls (Z = -7.639, P< 0.001), indicative of increased fibrotic changes. Conversely, TLV (Z =-3.120, P=0.002), TAV/TNV (Z = -9.564, P< 0.001), and LAA-950% (Z = -4.926, P < 0.001) were reduced in T2DM-ILAs patients. The correlation between HbA1c and various CT quantitative indicators was not significant, HbA1c and TLV (r=-0.043, P=0.618), HbA1c and TAV (r=0.143, P=0.099), HbA1c and TNV (r=0.064, P=0.461), HbA1c and LAA-700~-200% (r=0.102, P=0.239), HbA1c and LAA-950% (r=-0.170, P=0.049), HbA1c and TAV/TNV (r=0.175, P=0.043). The peripheral vascular marker, TAV/TNV, excelled in distinguishing T2DM-related lung changes (AUC=0.84, P<0.001), outperforming LAA-700~-200% (AUC=0.77,P<0.001). A composite index incorporating multiple quantitative parameters achieved the highest diagnostic accuracy (AUC = 0.91, P< 0.001).</p><p><strong>Conclusion: </strong>Quantitative CT parameters distinguish T2DM complicated with ILAs from non-diabetic individuals, suggesting a distinct pattern of lung injury. Our findings imply a particular susceptibility of small pulmonary blo","PeriodicalId":54215,"journal":{"name":"Current Medical Imaging Reviews","volume":" ","pages":""},"PeriodicalIF":1.1,"publicationDate":"2025-06-03","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144217528","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Deep Learning for Automated Prediction of Sphenoid Sinus Pneumatization in Computed Tomography.","authors":"Ali Alamer, Omar Salim, Fawaz Alharbi, Fahd Alsaleem, Afnan Almuqbil, Khaled Alhassoon, Fahad Alsunaydih","doi":"10.2174/0115734056363158250429101521","DOIUrl":"https://doi.org/10.2174/0115734056363158250429101521","url":null,"abstract":"<p><strong>Background: </strong>The sphenoid sinus is an important access point for trans-sphenoidal surgeries, but variations in its pneumatization may complicate surgical safety. Deep learning can be used to identify these anatomical variations.</p><p><strong>Methods: </strong>We developed a convolutional neural network (CNN) model for the automated prediction of sphenoid sinus pneumatization patterns in computed tomography (CT) scans. This model was tested on mid-sagittal CT images. Two radiologists labeled all CT images into four pneumatization patterns: Conchal (type I), presellar (type II), sellar (type III), and postsellar (type IV). We then augmented the training set to address the limited size and imbalanced nature of the data.</p><p><strong>Results: </strong>The initial dataset included 249 CT images, divided into training (n = 174) and test (n = 75) datasets. The training dataset was augmented to 378 images. Following augmentation, the overall diagnostic accuracy of the model improved from 76.71% to 84%, with an area under the curve (AUC) of 0.84, indicating very good diagnostic performance. Subgroup analysis showed excellent results for type IV, with the highest AUC of 0.93, perfect sensitivity (100%), and an F1-score of 0.94. The model also performed robustly for type I, achieving an accuracy of 97.33% and high specificity (99%). These metrics highlight the model's potential for reliable clinical application.</p><p><strong>Conclusion: </strong>The proposed CNN model demonstrates very good diagnostic accuracy in identifying various sphenoid sinus pneumatization patterns, particularly excelling in type IV, which is crucial for endoscopic sinus surgery due to its higher risk of surgical complications. By assisting radiologists and surgeons, this model enhances the safety of transsphenoidal surgery, highlighting its value, novelty, and applicability in clinical settings.</p>","PeriodicalId":54215,"journal":{"name":"Current Medical Imaging Reviews","volume":" ","pages":""},"PeriodicalIF":1.1,"publicationDate":"2025-05-22","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144144256","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Prediction of Monosodium Urate Crystal Deposits in the First Metatarsophalangeal Joint Using a Decision Tree Model.","authors":"Jiachun Zhuang, Lin Liu, Yingyi Zhu, Yunyan Zi, Hongjing Leng, Bei Weng, Lina Chen, Haijun Wu","doi":"10.2174/0115734056355443250505051813","DOIUrl":"https://doi.org/10.2174/0115734056355443250505051813","url":null,"abstract":"<p><strong>Background: </strong>Despite the increasing prevalence of hyperuricemia and gout, there remains a relative paucity of research focused on the use of straightforward clinical and laboratory markers to predict urate crystal formation. The identification of such predictive markers is crucial, as they would greatly enhance the ability of clinicians to make timely and accurate diagnoses, leading to more effective and targeted therapeutic interventions.</p><p><strong>Objective: </strong>The aim of this study was to evaluate the diagnostic value of various easily obtainable clinical and laboratory indicators and to establish a decision tree (DT) model to analyze their predictive significance for monosodium urate (MSU) deposition in the first metatarsophalangeal (MTP) joint.</p><p><strong>Methods: </strong>A retrospective study was conducted on 317 patients who presented to the outpatient clinic with a gout flare between January 2023 and June 2024 (181 cases with MSU deposition in the first MTP joint and 136 cases without such deposition). Clinical and laboratory indicators included gender, age, disease course, serum uric acid (SUA), glomerular filtration rate (GFR), serum creatinine (SCR), C-reactive protein (CRP), and erythrocyte sedimentation rate (ESR). Statistical analysis methods, including T-test, logistic regression and decision tree, were used to analyze the predictors of MSU deposition in the first MTP joint. The performance of the DT model was evaluated using receiver operating characteristic (ROC) curves and a 5-fold cross-validation method was used to ensure the robustness of the study results.</p><p><strong>Results: </strong>Disease course, GFR, SUA, age, and SCR emerged as significant predictors of MSU deposition in the first MTP joint in both LR and DT analyses. The DT model exhibited superior diagnostic performance compared to the LR model, with a sensitivity of 83.4% (151/181), specificity of 56.6% (77/136), and overall accuracy of 71.9% (228/317). The importance of predictive variables in the DT model showed disease course, GFR, SUA, age, and SCR as 53.36%, 21.51%, 15.1%, 5.5% and 4.53%, respectively. The area under the ROC curve predicted by the DT model was 0.752 (95% CI: 0.700~0.800).</p><p><strong>Conclusion: </strong>The DT model demonstrates strong predictive capability. Disease duration, GFR, SUA, age, and SCR are pivotal factors for predicting MSU deposition at the first MTP joint, with disease course being the most critical factor.</p>","PeriodicalId":54215,"journal":{"name":"Current Medical Imaging Reviews","volume":" ","pages":""},"PeriodicalIF":1.1,"publicationDate":"2025-05-22","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144144257","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Incidental Myocardial Infarction on Routine Non-Gated Thoracic Computed Tomography.","authors":"Mehrad Rokni, Yasser G Abdelhafez, Lorenzo Nardo, Mohammad H Madani","doi":"10.2174/0115734056363863250509093505","DOIUrl":"https://doi.org/10.2174/0115734056363863250509093505","url":null,"abstract":"<p><strong>Aims: </strong>The aim of this study is to assess the identification of incidental myocardial infarction on non-electrocardiogram-gated computed tomographic scans of the chest and its prognostic significance.</p><p><strong>Background: </strong>The increased utilization and abundance of thoracic computed tomographic (CT) scans have provided a substrate for potential screening purposes.</p><p><strong>Objective: </strong>The objective of this study was to evaluate the detection of incidental myocardial infarction on routine non-gated thoracic CT performed for noncardiac reasons and its associated major cardiovascular events and survival.</p><p><strong>Methods: </strong>We retrospectively assessed routine non-gated thoracic CT scans of all consecutive individuals aged 18 or above who underwent thoracic CT scans as outpatients at the University of California Davis from January 2015 to December 2015. We evaluated the presence and location of incidental MI on non-gated thoracic CT and compared major adverse cardiac events (MACE) and overall survival in CT-positive infarct individuals with a CTnegative infarct control group.</p><p><strong>Results: </strong>We reviewed routine thoracic CT scans of 1157 individuals and identified 12 individuals with incidental MI. The mean age of individuals with infarction was 71.4 ± 14.1 years, and 50% were female. All individuals with incidental MI had coronary calcification. Individuals with incidental MI had a higher rate of MACE endpoint (92% vs. 28%, p=0.0001), number of MACE events (1.1 vs. 0.3, p<0.001), and lower overall survival (median survival of 67 months vs. not reached, p=0.023) compared with age and sex-matched controls without incidental MI.</p><p><strong>Conclusion: </strong>Although small in number relative to the total number of individuals evaluated, subjects with incidental MI on routine non-gated thoracic CT scans have worse cardiovascular outcomes and survival compared with controls without infarction. This study highlights the potential opportunistic screening utility of routine thoracic CTs, which could lead to improved risk stratification and intervention.</p>","PeriodicalId":54215,"journal":{"name":"Current Medical Imaging Reviews","volume":" ","pages":""},"PeriodicalIF":1.1,"publicationDate":"2025-05-19","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144112707","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Magnetic Resonance Enterography of Phlebosclerotic Colitis: A Case Report.","authors":"Yu-Xuan Kho, Chien-Ming Chen, Sung-Yu Chu","doi":"10.2174/0115734056382571250509114555","DOIUrl":"https://doi.org/10.2174/0115734056382571250509114555","url":null,"abstract":"<p><strong>Background: </strong>Phlebosclerotic colitis is a rare type of chronic ischemic colitis, with most documented cases occurring in Asians. Plain-film and computed tomography findings of pericolonic vascular calcifications are diagnostic. However, Magnetic Resonance Enterography (MRE) findings of phlebosclerotic colitis have not yet been reported, and its diagnosis might be overlooked without awareness of this disease.</p><p><strong>Case report: </strong>A 70-year-old female patient without prior systemic disease presented with a 3-month history of nausea, vomiting, abdominal pain, and diarrhea. Personal history was unremarkable except for long-term use of herbal medicine. She was initially investigated at a regional hospital with a colonoscopy and biopsy. Due to the presence of stenosis at the transverse colon and biopsy results suggestive of Inflammatory Bowel Disease (IBD), she was referred to our hospital for further investigation and treatment. MRE was performed as part of the IBD workup, which showed a thickened ascending and transverse colonic wall that was fibrotic, non-edematous, and with triangular projections on the mesenteric aspect. Owing to findings that were inconsistent with IBD, subsequent abdominal plain-film radiography confirmed characteristic linear dendritic serpiginous radiopaque opacities alongside the ascending and transverse colon. Re-biopsy of the affected colon confirmed the diagnosis of phlebosclerotic colitis. The patient's symptoms improved after conservative treatment.</p><p><strong>Conclusion: </strong>MRE of phlebosclerotic colitis appears as symmetrical non-edematous bowel wall thickening with triangular signal voids indicative of venous calcifications.</p>","PeriodicalId":54215,"journal":{"name":"Current Medical Imaging Reviews","volume":" ","pages":""},"PeriodicalIF":1.1,"publicationDate":"2025-05-19","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144112737","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}