Current Medical Imaging Reviews最新文献_第6页

Head and Neck Imaging with a Dental CBCT Device: Comparison of 360° and 180° Rotation Angles in Effective Dose and Quantitative Image Quality in a Phantom Study 使用牙科CBCT设备进行头颈部成像：360°和180°旋转角度在幻象研究中有效剂量和定量图像质量的比较。

IF 1.1 4区医学

Current Medical Imaging Reviews Pub Date : 2025-04-17 DOI: 10.2174/0115734056316438241203095215

Hakan Amasya, Osman Günay, Fatih Kesmezacar, Duygu Tunçman, Nami Yeyin, Eylem Kekeç, Tülin Zengin, Kaan Orhan, Songül Çavdar Karaçam, Mustafa Demir

{"title":"Head and Neck Imaging with a Dental CBCT Device: Comparison of 360° and 180° Rotation Angles in Effective Dose and Quantitative Image Quality in a Phantom Study","authors":"Hakan Amasya, Osman Günay, Fatih Kesmezacar, Duygu Tunçman, Nami Yeyin, Eylem Kekeç, Tülin Zengin, Kaan Orhan, Songül Çavdar Karaçam, Mustafa Demir","doi":"10.2174/0115734056316438241203095215","DOIUrl":"10.2174/0115734056316438241203095215","url":null,"abstract":"Objectives: This study aims to investigate the effect of full- and half-rotation angles on patient radiation dose and quantitative image quality in CBCT imaging of the head and neck region.Methods: A total of 67 TLDs were used for the dosimetry of 16 different regions in the head and neck slices of the anthropometric phantom. The Hyperion X9 Pro (MyRay, Cefla, Imola, Italy) CBCT device was used with a 90 kV pulsed beam and a 13x16e FOV size. Two separate imaging modes (Regular 360 0 and Quick 180 0) were tested, and the mA was determined by the software. Effective doses (EDs) were calculated using the coefficients recommended by ICRP 103 (2007). For the quantitative image quality tests, three VOIs were manually selected for three separate densities in image slices selected from the mandible, maxilla, and paranasal sinus regions of both volumes separately. Pixel values were averaged, and signal-to-noise ratio (SNR), contrast-to-noise ratio (CNR), and uniformity tests were conducted.Results: In 360 0, ED was calculated as 1.903 mSv and the highest absorbed dose was found in the oral mucosa (1.566 mSv). In 180 0, ED was calculated as 1.123 mSv and the highest absorbed dose was found in the right temporal squamous region (0.984 mSv). The reduction in ED was found to be 41% for full- and half-rotation angles. Quick/Regular ratios for SNR and CNR were changed between 0.83-0.91.Conclusion: The magnitude of reduction in ED was found to be higher than the quantitative image quality; however, the impact of this change on diagnosis should be analyzed according to the imaging purpose.","PeriodicalId":54215,"journal":{"name":"Current Medical Imaging Reviews","volume":" ","pages":""},"PeriodicalIF":1.1,"publicationDate":"2025-04-17","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144063293","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

From Cup to Scan: The Impact of Black Tea on Magnetic Resonance Cholangiopancreatography Signal Suppression. 从杯到扫描：红茶对磁共振胆管造影信号抑制的影响。

IF 1.1 4区医学

Current Medical Imaging Reviews Pub Date : 2025-04-17 DOI: 10.2174/0115734056393392250414074014

Sihua Liang, Yiman Wang, Huiyi Liang, Xuefen Yu, Nengwei Wang, Lin Qiu

{"title":"From Cup to Scan: The Impact of Black Tea on Magnetic Resonance Cholangiopancreatography Signal Suppression.","authors":"Sihua Liang, Yiman Wang, Huiyi Liang, Xuefen Yu, Nengwei Wang, Lin Qiu","doi":"10.2174/0115734056393392250414074014","DOIUrl":"https://doi.org/10.2174/0115734056393392250414074014","url":null,"abstract":"Aims: The aim of this study is to evaluate the potential of black tea as a negative oral contrast agent in Magnetic Resonance Cholangiopancreatography (MRCP) to improve image quality by reducing gastrointestinal fluid signals.Background: Retained gastrointestinal fluids can interfere with ductal imaging during MRCP, and suitable oral negative contrast agents are not widely available.Method: Two types of black tea (Lapsang Souchong and Yinghong NO9) were tested in vitro at different concentrations (3g, 6g, and 9g) to assess their T2 signal suppression. The tea with the best signal suppression was selected for a prospective clinical study involving 51 patients undergoing MRCP. Signal intensity, signal-to-noise ratio (SNR), and contrast-to-noise ratio (CNR) were measured before and after black tea administration.Result: In vitro experiments showed that the 9g concentration of Lapsang Souchong tea provided the most effective T2 signal suppression, with manganese and iron ion concentrations of 4.705 mg/L and 0.040 mg/L, respectively. In the clinical study, paired T-tests revealed a significant decrease in gastrointestinal fluid signals after black tea administration, with a mean signal intensity reduction in the stomach and duodenum. The SNR in the duodenal bulb increased significantly, while no significant differences were observed in SNR and CNR in other gastrointestinal segments.Conclusion: Black tea, rich in iron and manganese, effectively reduces gastrointestinal fluid signals, potentially enhancing MRCP image quality. Further research is warranted to explore its clinical application.","PeriodicalId":54215,"journal":{"name":"Current Medical Imaging Reviews","volume":" ","pages":""},"PeriodicalIF":1.1,"publicationDate":"2025-04-17","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143999665","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Research Progress of Dual-Energy CT in Diagnosis and Evaluation of Curative Effect of Liver Cancer: A Review. 双能CT在肝癌诊断及疗效评价中的研究进展

IF 1.1 4区医学

Current Medical Imaging Reviews Pub Date : 2025-04-17 DOI: 10.2174/0115734056335472250310085121

Mingtai Cao, Yumiao Qiao, Xukun Gao, Xinyi Liu, Airu Yang, Rui Fan, Boqi Zhou, Bin Huang, Yuntai Cao

{"title":"Research Progress of Dual-Energy CT in Diagnosis and Evaluation of Curative Effect of Liver Cancer: A Review.","authors":"Mingtai Cao, Yumiao Qiao, Xukun Gao, Xinyi Liu, Airu Yang, Rui Fan, Boqi Zhou, Bin Huang, Yuntai Cao","doi":"10.2174/0115734056335472250310085121","DOIUrl":"https://doi.org/10.2174/0115734056335472250310085121","url":null,"abstract":"Primary liver cancer is the sixth most common cancer and the third leading cause of cancer deaths worldwide, with over 900,000 new cases and more than 800,000 deaths annually. Conventional imaging techniques have improved the diagnosis and assessment of treatment response in patients with Hepatocellular Carcinoma (HCC), but they have many limitations. Introducing Dual-Energy Computed Tomography (DECT) into clinical practice offers an opportunity to address these issues. DECT has unique advantages in diagnosing and evaluating the efficacy of HCC treatment. It can provide quantitative information on various substances and, through multi-parameter and quantitative parameter analysis, can be used for early detection of HCC, identification of benign and malignant lesions, and monitoring of lymph node metastasis and Microvascular Invasion (MVI). Additionally, DECT provides valuable information for evaluating therapeutic efficacy. This review covers the imaging principles of DECT, including its basic principles, scanner design modes, and Image Reconstruction (IR) techniques. It then describes the research progress of DECT in diagnosing HCC and evaluating treatment efficacy. Finally, it briefly discusses some limitations of DECT and its future development directions.","PeriodicalId":54215,"journal":{"name":"Current Medical Imaging Reviews","volume":" ","pages":""},"PeriodicalIF":1.1,"publicationDate":"2025-04-17","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144018388","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

A Retrospective Analysis: CCTA vs. TTE in Diagnosing Coronary Artery Fistula. CCTA与TTE诊断冠状动脉瘘的回顾性分析。

IF 1.1 4区医学

Current Medical Imaging Reviews Pub Date : 2025-04-17 DOI: 10.2174/0115734056333289250311184106

XiaoLi Hu, Jian Shen, ChunLi He, YueMei Li, Shen Gui, YuKun Cao, Ping Han, Jun Xu

{"title":"A Retrospective Analysis: CCTA vs. TTE in Diagnosing Coronary Artery Fistula.","authors":"XiaoLi Hu, Jian Shen, ChunLi He, YueMei Li, Shen Gui, YuKun Cao, Ping Han, Jun Xu","doi":"10.2174/0115734056333289250311184106","DOIUrl":"https://doi.org/10.2174/0115734056333289250311184106","url":null,"abstract":"Objective This study aimed to compare and analyze the diagnostic performance of cardiac computed tomographic angiography (CCTA) and transthoracic echocardiography (TTE) for coronary artery fistula (CAF) and evaluate the effectiveness of these two imaging modalities. Methods We retrospectively collected and analyzed imaging data from 200 patients diagnosed with CAF through surgery or digital subtraction angiography (DSA). These patients underwent CCTA and TTE examinations in our hospital. Finally, the course, origin, number, size, and location of the CAF in all patients were assessed. The diagnostic results of CCTA were compared with those of TTE, using DSA and/or surgical diagnosis as the reference standard. Results Among the 200 patients with CAF, CCTA correctly diagnosed 156 cases, but missed 44 cases, resulting in a diagnostic accuracy of 78.0% (156/200). In contrast, TTE accurately diagnosed 55 cases, but missed 145 cases, yielding a diagnostic accuracy of 27.5% (55/200). The diagnostic accuracy of CCTA was significantly higher than that of TTE in detecting CAF (P < 0.001). Conclusion CCTA demonstrated significantly greater diagnostic value than TTE, demonstrating to be the preferred imaging modality for diagnosing CAF.","PeriodicalId":54215,"journal":{"name":"Current Medical Imaging Reviews","volume":" ","pages":""},"PeriodicalIF":1.1,"publicationDate":"2025-04-17","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144008180","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

The Impact of Therapeutic Ultrasound on Bone Radio Density Following Orthodontic Treatment with Clear Aligners: A Preliminary Study. 正畸清除矫正器治疗后超声对骨密度影响的初步研究。

IF 1.1 4区医学

Current Medical Imaging Reviews Pub Date : 2025-04-17 DOI: 10.2174/0115734056371884250324151755

Mohsen Gholizadeh, Hollis Lai, Lindsey Westover, Tarek El-Bialy

{"title":"The Impact of Therapeutic Ultrasound on Bone Radio Density Following Orthodontic Treatment with Clear Aligners: A Preliminary Study.","authors":"Mohsen Gholizadeh, Hollis Lai, Lindsey Westover, Tarek El-Bialy","doi":"10.2174/0115734056371884250324151755","DOIUrl":"https://doi.org/10.2174/0115734056371884250324151755","url":null,"abstract":"Objective: This study evaluated the impact of Low-Intensity Pulsed Ultrasound (LIPUS) on bone radio density in patients undergoing orthodontic treatment with clear aligners, aiming to enhance bone remodeling and improve treatment stability.Methods: This retrospective study included 68 participants divided into two groups: 34 treated with LIPUS and 34 in a control group. Bone radio density was measured using Hounsfield units from CBCT scans before and after treatment. Statistical analyses included Mann-Whitney U tests and paired ttests.Results: The average age was 29.85 ± 14.85 years in the control group and 36.29 ± 12.78 years in the LIPUS group. Bone radio density in the upper arch of the LIPUS group significantly increased from 444.6 HU to 751.3 HU (p < 0.001), while the control group showed a slight decrease in the upper arch (657.4 HU to 650.5 HU, p = 0.86). In the lower arch, a similar trend was observed in the LIPUS group, with an increase from 767.7 HU to 823.4 HU (p = 0.17), though not statistically significant. There were no significant differences in post-treatment ABO DI scores between groups, suggesting equivalent effectiveness in achieving orthodontic outcomes.Conclusion: LIPUS with clear aligners seems promising in enhancing bone radio density, indicating an improved bone remodeling effect. This highlights LIPUS's potential as a beneficial adjunct in orthodontic treatments.","PeriodicalId":54215,"journal":{"name":"Current Medical Imaging Reviews","volume":" ","pages":""},"PeriodicalIF":1.1,"publicationDate":"2025-04-17","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144059165","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Efficacy of Thrombin Solution Injection Combined with Rapid Biopsy-Side Down Position Technique in CT-guided Lung Biopsy: A Propensity Score Matching Analysis. 凝血酶溶液注射联合快速活检侧下位技术在ct引导下肺活检中的疗效：倾向评分匹配分析。

IF 1.1 4区医学

Current Medical Imaging Reviews Pub Date : 2025-04-09 DOI: 10.2174/0115734056342141250320084906

Baijintao Sun, Bing Li, Chuan Zhang, Yan Liu, Qing Zhang

{"title":"Efficacy of Thrombin Solution Injection Combined with Rapid Biopsy-Side Down Position Technique in CT-guided Lung Biopsy: A Propensity Score Matching Analysis.","authors":"Baijintao Sun, Bing Li, Chuan Zhang, Yan Liu, Qing Zhang","doi":"10.2174/0115734056342141250320084906","DOIUrl":"https://doi.org/10.2174/0115734056342141250320084906","url":null,"abstract":"Objective: The objective of this study is to investigate the effect of thrombin solution injection combined with the rapid biopsy-side down position technique on the incidence of pneumothorax in emphysema patients following computed tomography (CT)-guided lung biopsy based on propensity score matching.Materials & methods: A retrospective study was conducted on emphysema patients who underwent CT-guided percutaneous lung biopsy between May 2022 and July 2023. Patients were divided into two groups based on the use of the rapid biopsy-side-down position technique. Propensity score matching was then applied to explore correlations.Results: A total of 212 patients were included in the study. Before propensity score matching, there were no significant differences between Groups A and B in terms of sex, lesion size, puncture path length, or patient positioning in multivariate logistic regression analysis. After matching with a 1:1 ratio, 41 patients were successfully paired. Logistic regression analysis revealed that the rapid biopsy-side down position technique was significantly correlated with a reduced incidence of pneumothorax (p = 0.027), serving as a protective factor.Conclusion: The combination of thrombin solution injection and the rapid biopsy-side down position technique significantly reduces the incidence of pneumothorax in emphysema patients following CT-guided lung biopsy.","PeriodicalId":54215,"journal":{"name":"Current Medical Imaging Reviews","volume":" ","pages":""},"PeriodicalIF":1.1,"publicationDate":"2025-04-09","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144026683","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Short-term MRI Follow-up and Thin-layer PDWI Sequence without Fat Suppression for Detecting Cartilage Loose Bodies: A Case Report. 短期MRI随访及无脂肪抑制的薄层PDWI序列检测软骨松体1例。

IF 1.1 4区医学

Current Medical Imaging Reviews Pub Date : 2025-04-09 DOI: 10.2174/0115734056354843250321170055

Ying Liu, Lei Gao, Junfei Li, Jujia Li, Jian Zhao

{"title":"Short-term MRI Follow-up and Thin-layer PDWI Sequence without Fat Suppression for Detecting Cartilage Loose Bodies: A Case Report.","authors":"Ying Liu, Lei Gao, Junfei Li, Jujia Li, Jian Zhao","doi":"10.2174/0115734056354843250321170055","DOIUrl":"https://doi.org/10.2174/0115734056354843250321170055","url":null,"abstract":"Background: Osteochondritis Dissecans (OCD) is an idiopathic process and can progress from stable to cartilage fragmentation with the formation of loose bodies in the affected joint capsule. Loose bodies in the knee may wear out the articular cartilage, tendons, and ligaments, leading to a series of problems, such as joint locking, bouncing, joint effusion, and meniscus tear; therefore, early recognition and treatment of intraarticular loose bodies are important to achieve favorable long-term outcomes.Case report: A 49-year-old male presented with a 1-month history of right knee discomfort. The patient underwent a knee MRI scan and was diagnosed with OCD. A short-term MRI follow-up with a thin-layer PDWI sequence without fat suppression detected the cartilage fragments in the knee capsule. Loose body removal, cartilage repair, and microfracture surgery were performed under arthroscopic surgery, and loose bodies of cartilage fragments were removed.Conclusion: Short-term MRI follow-up and thin-layer PDWI sequence without fat suppression are necessary for detecting cartilage loose bodies.","PeriodicalId":54215,"journal":{"name":"Current Medical Imaging Reviews","volume":" ","pages":""},"PeriodicalIF":1.1,"publicationDate":"2025-04-09","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144032394","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Sparse-View CT Joint Reconstruction Strategy with Sparse Sampling Encoding Layer. 基于稀疏采样编码层的稀疏视图CT联合重建策略。

IF 1.1 4区医学

Current Medical Imaging Reviews Pub Date : 2025-03-25 DOI: 10.2174/0115734056354972250221012822

Hu Guo, Minghan Yang, Ziheng Zhang, Haibo Yu, Shuai Chen, Jianye Wang, Minghao Li

{"title":"Sparse-View CT Joint Reconstruction Strategy with Sparse Sampling Encoding Layer.","authors":"Hu Guo, Minghan Yang, Ziheng Zhang, Haibo Yu, Shuai Chen, Jianye Wang, Minghao Li","doi":"10.2174/0115734056354972250221012822","DOIUrl":"https://doi.org/10.2174/0115734056354972250221012822","url":null,"abstract":"Background: Sparse angular projection is an important way to reduce CT dose. It consists of two processes, sparse sampling, and image reconstruction based on sparse projection. Under the traditional reconstruction framework, the sparseness of the projection angle may cause a degradation effect in the reconstructed image. A series of machine learning methods for sparse angle CT reconstruction developed in recent years, especially deep learning methods, can effectively improve the reconstruction quality, however, these methods can only reconstruct CT images based on a certain sparse sampling scheme.Objective: On the other words, they cannot search for an efficient sparse sampling scheme under a certain dose constraint automatically, which became the motivation to develop an end-to-end sparse angular CT reconstruction method.Methods: In this work, we propose a sampling encoding layer for searching sparse sampling schemes and integrate it into a sparse reconstruction neural network model based on projection data. Meanwhile, a joint reconstruction strategy based on both the radon domain and image domain painting is also developed.Results: Experiments based on public CT datasets demonstrate the effectiveness of the method.Conclusion: The results show that the joint reconstruction network based on a sparse sampling coding layer has great application potential.","PeriodicalId":54215,"journal":{"name":"Current Medical Imaging Reviews","volume":" ","pages":""},"PeriodicalIF":1.1,"publicationDate":"2025-03-25","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143722423","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Recurrence of Pleomorphic Adenoma in the Submandibular Gland: A Case Report and Literature Review. 颌下腺多形性腺瘤复发1例并文献复习。

IF 1.1 4区医学

Current Medical Imaging Reviews Pub Date : 2025-03-25 DOI: 10.2174/0115734056333595250226071534

Zhiqiong Li, Guiying Yuan, Ye Zhang, Junbin Huang, Fan Xu, Yuchao Xiong, Xuwen Zeng

{"title":"Recurrence of Pleomorphic Adenoma in the Submandibular Gland: A Case Report and Literature Review.","authors":"Zhiqiong Li, Guiying Yuan, Ye Zhang, Junbin Huang, Fan Xu, Yuchao Xiong, Xuwen Zeng","doi":"10.2174/0115734056333595250226071534","DOIUrl":"https://doi.org/10.2174/0115734056333595250226071534","url":null,"abstract":"Introduction: Recurrent pleomorphic adenoma (PA) in the submandibular gland is a rare tumor that may be misdiagnosed as an inflammatory lesion. The imaging manifestations of the submandibular gland recurrent PA are unclear, with only three case reports reporting CT and MRI imaging, respectively. Our report is the first case report that comprehensively describes the imaging manifestations of recurrent PA in the submandibular gland.Case presentation: A 28-year-old woman had a right submandibular gland pleomorphic adenoma that recurred 5 years after resection and gradually grew larger. She had no special discomfort and was diagnosed with a recurrence of pleomorphic adenoma. The patient underwent CT and MRI examinations and tumor resection, and postoperative pathology showed tumor recurrence.Conclusion: This case report provides substantial and comprehensive CT and MRI data, which is conducive to the diagnosis of the recurrence of submandibular gland pleomorphic adenoma and the avoidance of misdiagnosis to the greatest extent possible.","PeriodicalId":54215,"journal":{"name":"Current Medical Imaging Reviews","volume":" ","pages":""},"PeriodicalIF":1.1,"publicationDate":"2025-03-25","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143722418","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Severe Disseminated Cryptococcosis Leading to Multi-Organ Failure in a Renal Transplant Patient: A Case Report. 肾移植患者严重播散性隐球菌病导致多器官功能衰竭1例报告。

IF 1.1 4区医学

Current Medical Imaging Reviews Pub Date : 2025-03-25 DOI: 10.2174/0115734056353324250302180953

Daniela Sanchez-Lobo, Paulina Espinosa-Zerecero, Ricardo Cebrian-Garcia, Marcos Garcia-Nava, Fernando Cano-Garcia, Maria-Del-Carmen Garcia-Blanco, Ernesto Roldan-Valadez

{"title":"Severe Disseminated Cryptococcosis Leading to Multi-Organ Failure in a Renal Transplant Patient: A Case Report.","authors":"Daniela Sanchez-Lobo, Paulina Espinosa-Zerecero, Ricardo Cebrian-Garcia, Marcos Garcia-Nava, Fernando Cano-Garcia, Maria-Del-Carmen Garcia-Blanco, Ernesto Roldan-Valadez","doi":"10.2174/0115734056353324250302180953","DOIUrl":"https://doi.org/10.2174/0115734056353324250302180953","url":null,"abstract":"Background Cryptococcosis is a severe but rare opportunistic fungal infection predominantly affecting immunocompromised individuals, such as posttransplant patients. The diagnosis is frequently delayed due to non-specific symptoms and lower incidence than other fungal infections. Case Report A case of a 50-year-old male renal transplant recipient who developed disseminated cryptococcosis complicated by multi-organ failure is presented. Despite adherence to international treatment guidelines, the patient's condition rapidly deteriorated due to the extensive immunosuppression required for transplant rejection management. The patient developed pneumonia and was diagnosed with disseminated cryptococcosis on the 10th day of hospitalization, with Cryptococcus gattii identified in the pulmonary system and pleura. The patient underwent multiple interventions, including bronchoscopy, lobectomy, and pneumonectomy. Despite aggressive treatment, the infection progressed, leading to severe complications, such as neurological decline, gastrointestinal bleeding, and ultimately, multi-organ failure. The patient passed away after 53 days of hospitalization. Conclusion This report highlights the importance of early diagnosis and multidisciplinary management in post-transplant patients with suspected opportunistic infections. The high mortality associated with disseminated cryptococcosis, particularly in severely immunosuppressed patients, underscores the need for vigilance and prompt intervention to improve patient outcomes.","PeriodicalId":54215,"journal":{"name":"Current Medical Imaging Reviews","volume":" ","pages":""},"PeriodicalIF":1.1,"publicationDate":"2025-03-25","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143732667","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0