{"title":"Radiomics of Vascular Structures in Pulmonary Ground-Glass Nodules: A Predictor of Invasiveness : Radiomics of Vascular Structures in GGNs for Tumor Invasiveness Prediction.","authors":"Wuling Wang, Xuan Qi, Yongsheng He, Hongkai Yang, Dong Qi, Zhen Tang, Qiong Chen","doi":"10.2174/0115734056385352250410053810","DOIUrl":"https://doi.org/10.2174/0115734056385352250410053810","url":null,"abstract":"<p><p>Objective The global incidence of lung cancer highlights the need for improved assessment of nodule characteristics to enhance early detection of lung adenocarcinoma presenting as ground-glass nodules (GGNs). This study investigated the applicability of radiomics features of vascular structures within GGNs for predicting invasiveness of GGNs. Methods In total, 165 pathologically confirmed pulmonary GGNs were retrospectively analyzed. The nodules were classified into preinvasive and invasive groups and randomly categorized into training and validation sets in a 7:3 ratio. Four models were constructed and evaluated: radiomics-GGN, radiomics-vascular, clinical-radiomics-GGN, and clinical-radiomics-vascular. The predictive performance of these models was assessed using receiver operating characteristic curves, decision curve analysis, calibration curves, and DeLong's test. Results Significant differences were observed between the preinvasive and invasive groups in terms of age, nodule length, average diameter, morphology, and lobulation sign (P = 0.006, 0.038, 0.046, 0.049, and 0.002, respectively). In the radiomics-GGN model, the support vector machine (SVM) approach outperformed logistic regression (LR), achieving an area under the curve (AUC) of 0.958 in the training set and 0.763 in the validation set. Similarly, in the radiomics-vascular model, the SVM approach outperformed LR. Furthermore, the clinical-radiomics-vascular model demonstrated superior predictive performance compared with the clinical-radiomics-GGN model, with an AUC of 0.918 in the training set and 0.864 in the validation set. DeLong's test indicated significant differences in predicting the invasiveness of pulmonary nodules between the clinical-radiomics-vascular model and the clinical-radiomics-GGN model, both in the training and validation sets (P < 0.01). Conclusion The radiomics models based on internal vascular structures of GGNs outperformed those based on GGNs alone, suggesting that incorporating vascular radiomics analysis can improve the noninvasive assessment of GGN invasiveness, thereby aiding in clinical decision-making and guiding biopsy selection and treatment planning.</p>","PeriodicalId":54215,"journal":{"name":"Current Medical Imaging Reviews","volume":" ","pages":""},"PeriodicalIF":1.1,"publicationDate":"2025-04-21","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144058106","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Neuronal Intranuclear Inclusion Disease: A Confirmed Case Report and Analysis of MRI Characteristics in Three Typical Cases.","authors":"Jin Liu, Chuan Zhang, Jiwu Wang, Hanfeng Yang","doi":"10.2174/0115734056335449250407103447","DOIUrl":"https://doi.org/10.2174/0115734056335449250407103447","url":null,"abstract":"<p><strong>Objective: </strong>Neuronal Intranuclear Inclusion Disease (NIID) is a rare and clinically heterogeneous neurodegenerative disorder leading to diagnostic challenges. This study aims to investigate the clinical and characteristic radiological features of four adult female patients, offering insights into the clinical and radiological heterogeneity of NIID and its misdiagnosis potential.</p><p><strong>Case representation: </strong>This case study presents a retrospective analysis of clinical data from four adult female patients, including one confirmed case and three with typical Magnetic Resonance Imaging (MRI) manifestations. The high signal intensity patterns on Diffusion-Weighted Imaging (DWI) and Fluid- Attenuated Inversion Recovery (FLAIR) sequences were reviewed in focus.</p><p><strong>Discussion: </strong>All four patients were adult females with common symptoms of NIID, such as recurrent headaches, cognitive decline, and autonomic dysfunction, accompanied by symptoms like vomiting, slowed responses, behavioral changes, and focal neurological symptoms. Genetic testing revealed a NOTCH2NLC gene mutation with GGC>113 repeats in one patient. Three patients from the same family presented with headaches, followed by vomiting and progressive unresponsiveness with two of them exhibiting abnormal behavior and one experiencing weakness and pain in the right limbs. Neurological assessments revealed peripheral neuropathy and intermittent confusion, among other manifestations. MRI features of all four patients were consistent with NIID, displaying high signals at the corticospinal junction on DWI and FLAIR sequences, with one case involving the vermis of the cerebellum.</p><p><strong>Conclusion: </strong>This case report enhances our understanding of NIID's diverse clinical phenotypes and the critical role of advanced MRI and genetic testing in its diagnosis. The core imaging feature of NIID is the high signal along the corticospinal junction on MRI, which, combined with NOTCH2NLC gene testing, can significantly enhance the early recognition and diagnosis of NIID. Therefore, this study deepens our understanding of the complex clinical phenotypes and imaging characteristics of NIID, providing crucial guidance for clinical practice.</p>","PeriodicalId":54215,"journal":{"name":"Current Medical Imaging Reviews","volume":" ","pages":""},"PeriodicalIF":1.1,"publicationDate":"2025-04-21","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143999715","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Xiaocai Zhang, Hongyue Tao, Zhenqing Liu, Zidong Zhou, Li Huang, Guangbi Song
{"title":"MR Imaging Features of Juvenile Pilocytic Astrocytoma in the Suprasellar Region: A Study on 11 Patients.","authors":"Xiaocai Zhang, Hongyue Tao, Zhenqing Liu, Zidong Zhou, Li Huang, Guangbi Song","doi":"10.2174/0115734056347108250318083203","DOIUrl":"https://doi.org/10.2174/0115734056347108250318083203","url":null,"abstract":"<p><strong>Objective: </strong>This study aimed to characterize the magnetic resonance imaging (MRI) findings of juvenile suprasellar pilocytic astrocytoma (PA) in a sample of 11 children and help neuroradiologists preoperatively differentiate PAs from other suprasellar tumors.</p><p><strong>Methods: </strong>Eleven consecutive children with pathologically confirmed suprasellar PAs in our hospital from May 2015 to November 2021 were enrolled in this study. The clinical data and preoperative MR images were retrospectively reviewed. MRI included T1-weighted imaging (T1WI), T2-weighted imaging (T2WI), fluid-attenuated inversion recovery (FLAIR), and postcontrast T1WI. Six patients underwent diffusion-weighted imaging (DWI). The location, signal features, enhancement pattern, and apparent diffusion coefficient (ADC) of the lesions on MRI were evaluated. The clinical status of the patients 3 years after surgery was noted.</p><p><strong>Results: </strong>The 11 suprasellar PAs were mainly located around the optic chiasma and hypothalamus and invaded adjacent structures. The lesions showed hyperintensity or slight hyperintensity on T2WI and hypointensity on T1WI. Among the 11 patients, 5 had solid tumors with homogeneous enhancement, one had a solid tumor with heterogeneous enhancement, and five had cystic and solid tumors with heterogeneous enhancement. Cerebrospinal fluid (CSF) dissemination foci were observed in 4 patients. The solid components of the lesions were hypointense or isointense on DWI, with high ADC values at a mean of 1.77±0.36 ×10-3 mm2/s. Gross total resection was achieved in only one patient (9.1%), and 10 (90.9%) were subtotally resected. Five patients died during the follow-up period, and the 3-year survival rate was 54.5%.</p><p><strong>Conclusion: </strong>Juvenile suprasellar PAs are characterized by a solid and intermixed cystic and solid appearance, hyperintensity on T2W images, obvious enhancement of the solid component, and relatively high ADC values.</p>","PeriodicalId":54215,"journal":{"name":"Current Medical Imaging Reviews","volume":" ","pages":""},"PeriodicalIF":1.1,"publicationDate":"2025-04-17","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144058090","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Hakan Amasya, Osman Günay, Fatih Kesmezacar, Duygu Tunçman, Nami Yeyin, Eylem Kekeç, Tülin Zengin, Kaan Orhan, Songül Çavdar Karaçam, Mustafa Demir
{"title":"Head and Neck Imaging with a Dental CBCT Device: Comparison of 360° and 180° Rotation Angles in Effective Dose and Quantitative Image Quality in a Phantom Study","authors":"Hakan Amasya, Osman Günay, Fatih Kesmezacar, Duygu Tunçman, Nami Yeyin, Eylem Kekeç, Tülin Zengin, Kaan Orhan, Songül Çavdar Karaçam, Mustafa Demir","doi":"10.2174/0115734056316438241203095215","DOIUrl":"10.2174/0115734056316438241203095215","url":null,"abstract":"<p><strong>Objectives: </strong>This study aims to investigate the effect of full- and half-rotation angles on patient radiation dose and quantitative image quality in CBCT imaging of the head and neck region.</p><p><strong>Methods: </strong>A total of 67 TLDs were used for the dosimetry of 16 different regions in the head and neck slices of the anthropometric phantom. The Hyperion X9 Pro (MyRay, Cefla, Imola, Italy) CBCT device was used with a 90 kV pulsed beam and a 13x16e FOV size. Two separate imaging modes (Regular 360 0 and Quick 180 0) were tested, and the mA was determined by the software. Effective doses (EDs) were calculated using the coefficients recommended by ICRP 103 (2007). For the quantitative image quality tests, three VOIs were manually selected for three separate densities in image slices selected from the mandible, maxilla, and paranasal sinus regions of both volumes separately. Pixel values were averaged, and signal-to-noise ratio (SNR), contrast-to-noise ratio (CNR), and uniformity tests were conducted.</p><p><strong>Results: </strong>In 360 0, ED was calculated as 1.903 mSv and the highest absorbed dose was found in the oral mucosa (1.566 mSv). In 180 0, ED was calculated as 1.123 mSv and the highest absorbed dose was found in the right temporal squamous region (0.984 mSv). The reduction in ED was found to be 41% for full- and half-rotation angles. Quick/Regular ratios for SNR and CNR were changed between 0.83-0.91.</p><p><strong>Conclusion: </strong>The magnitude of reduction in ED was found to be higher than the quantitative image quality; however, the impact of this change on diagnosis should be analyzed according to the imaging purpose.</p>","PeriodicalId":54215,"journal":{"name":"Current Medical Imaging Reviews","volume":" ","pages":""},"PeriodicalIF":1.1,"publicationDate":"2025-04-17","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144063293","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"From Cup to Scan: The Impact of Black Tea on Magnetic Resonance Cholangiopancreatography Signal Suppression.","authors":"Sihua Liang, Yiman Wang, Huiyi Liang, Xuefen Yu, Nengwei Wang, Lin Qiu","doi":"10.2174/0115734056393392250414074014","DOIUrl":"https://doi.org/10.2174/0115734056393392250414074014","url":null,"abstract":"<p><strong>Aims: </strong>The aim of this study is to evaluate the potential of black tea as a negative oral contrast agent in Magnetic Resonance Cholangiopancreatography (MRCP) to improve image quality by reducing gastrointestinal fluid signals.</p><p><strong>Background: </strong>Retained gastrointestinal fluids can interfere with ductal imaging during MRCP, and suitable oral negative contrast agents are not widely available.</p><p><strong>Method: </strong>Two types of black tea (Lapsang Souchong and Yinghong NO9) were tested in vitro at different concentrations (3g, 6g, and 9g) to assess their T2 signal suppression. The tea with the best signal suppression was selected for a prospective clinical study involving 51 patients undergoing MRCP. Signal intensity, signal-to-noise ratio (SNR), and contrast-to-noise ratio (CNR) were measured before and after black tea administration.</p><p><strong>Result: </strong>In vitro experiments showed that the 9g concentration of Lapsang Souchong tea provided the most effective T2 signal suppression, with manganese and iron ion concentrations of 4.705 mg/L and 0.040 mg/L, respectively. In the clinical study, paired T-tests revealed a significant decrease in gastrointestinal fluid signals after black tea administration, with a mean signal intensity reduction in the stomach and duodenum. The SNR in the duodenal bulb increased significantly, while no significant differences were observed in SNR and CNR in other gastrointestinal segments.</p><p><strong>Conclusion: </strong>Black tea, rich in iron and manganese, effectively reduces gastrointestinal fluid signals, potentially enhancing MRCP image quality. Further research is warranted to explore its clinical application.</p>","PeriodicalId":54215,"journal":{"name":"Current Medical Imaging Reviews","volume":" ","pages":""},"PeriodicalIF":1.1,"publicationDate":"2025-04-17","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143999665","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Mingtai Cao, Yumiao Qiao, Xukun Gao, Xinyi Liu, Airu Yang, Rui Fan, Boqi Zhou, Bin Huang, Yuntai Cao
{"title":"Research Progress of Dual-Energy CT in Diagnosis and Evaluation of Curative Effect of Liver Cancer: A Review.","authors":"Mingtai Cao, Yumiao Qiao, Xukun Gao, Xinyi Liu, Airu Yang, Rui Fan, Boqi Zhou, Bin Huang, Yuntai Cao","doi":"10.2174/0115734056335472250310085121","DOIUrl":"https://doi.org/10.2174/0115734056335472250310085121","url":null,"abstract":"<p><p>Primary liver cancer is the sixth most common cancer and the third leading cause of cancer deaths worldwide, with over 900,000 new cases and more than 800,000 deaths annually. Conventional imaging techniques have improved the diagnosis and assessment of treatment response in patients with Hepatocellular Carcinoma (HCC), but they have many limitations. Introducing Dual-Energy Computed Tomography (DECT) into clinical practice offers an opportunity to address these issues. DECT has unique advantages in diagnosing and evaluating the efficacy of HCC treatment. It can provide quantitative information on various substances and, through multi-parameter and quantitative parameter analysis, can be used for early detection of HCC, identification of benign and malignant lesions, and monitoring of lymph node metastasis and Microvascular Invasion (MVI). Additionally, DECT provides valuable information for evaluating therapeutic efficacy. This review covers the imaging principles of DECT, including its basic principles, scanner design modes, and Image Reconstruction (IR) techniques. It then describes the research progress of DECT in diagnosing HCC and evaluating treatment efficacy. Finally, it briefly discusses some limitations of DECT and its future development directions.</p>","PeriodicalId":54215,"journal":{"name":"Current Medical Imaging Reviews","volume":" ","pages":""},"PeriodicalIF":1.1,"publicationDate":"2025-04-17","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144018388","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"A Retrospective Analysis: CCTA <i>vs.</i> TTE in Diagnosing Coronary Artery Fistula.","authors":"XiaoLi Hu, Jian Shen, ChunLi He, YueMei Li, Shen Gui, YuKun Cao, Ping Han, Jun Xu","doi":"10.2174/0115734056333289250311184106","DOIUrl":"https://doi.org/10.2174/0115734056333289250311184106","url":null,"abstract":"<p><p>Objective This study aimed to compare and analyze the diagnostic performance of cardiac computed tomographic angiography (CCTA) and transthoracic echocardiography (TTE) for coronary artery fistula (CAF) and evaluate the effectiveness of these two imaging modalities. Methods We retrospectively collected and analyzed imaging data from 200 patients diagnosed with CAF through surgery or digital subtraction angiography (DSA). These patients underwent CCTA and TTE examinations in our hospital. Finally, the course, origin, number, size, and location of the CAF in all patients were assessed. The diagnostic results of CCTA were compared with those of TTE, using DSA and/or surgical diagnosis as the reference standard. Results Among the 200 patients with CAF, CCTA correctly diagnosed 156 cases, but missed 44 cases, resulting in a diagnostic accuracy of 78.0% (156/200). In contrast, TTE accurately diagnosed 55 cases, but missed 145 cases, yielding a diagnostic accuracy of 27.5% (55/200). The diagnostic accuracy of CCTA was significantly higher than that of TTE in detecting CAF (P < 0.001). Conclusion CCTA demonstrated significantly greater diagnostic value than TTE, demonstrating to be the preferred imaging modality for diagnosing CAF.</p>","PeriodicalId":54215,"journal":{"name":"Current Medical Imaging Reviews","volume":" ","pages":""},"PeriodicalIF":1.1,"publicationDate":"2025-04-17","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144008180","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"The Impact of Therapeutic Ultrasound on Bone Radio Density Following Orthodontic Treatment with Clear Aligners: A Preliminary Study.","authors":"Mohsen Gholizadeh, Hollis Lai, Lindsey Westover, Tarek El-Bialy","doi":"10.2174/0115734056371884250324151755","DOIUrl":"https://doi.org/10.2174/0115734056371884250324151755","url":null,"abstract":"<p><strong>Objective: </strong>This study evaluated the impact of Low-Intensity Pulsed Ultrasound (LIPUS) on bone radio density in patients undergoing orthodontic treatment with clear aligners, aiming to enhance bone remodeling and improve treatment stability.</p><p><strong>Methods: </strong>This retrospective study included 68 participants divided into two groups: 34 treated with LIPUS and 34 in a control group. Bone radio density was measured using Hounsfield units from CBCT scans before and after treatment. Statistical analyses included Mann-Whitney U tests and paired ttests.</p><p><strong>Results: </strong>The average age was 29.85 ± 14.85 years in the control group and 36.29 ± 12.78 years in the LIPUS group. Bone radio density in the upper arch of the LIPUS group significantly increased from 444.6 HU to 751.3 HU (p < 0.001), while the control group showed a slight decrease in the upper arch (657.4 HU to 650.5 HU, p = 0.86). In the lower arch, a similar trend was observed in the LIPUS group, with an increase from 767.7 HU to 823.4 HU (p = 0.17), though not statistically significant. There were no significant differences in post-treatment ABO DI scores between groups, suggesting equivalent effectiveness in achieving orthodontic outcomes.</p><p><strong>Conclusion: </strong>LIPUS with clear aligners seems promising in enhancing bone radio density, indicating an improved bone remodeling effect. This highlights LIPUS's potential as a beneficial adjunct in orthodontic treatments.</p>","PeriodicalId":54215,"journal":{"name":"Current Medical Imaging Reviews","volume":" ","pages":""},"PeriodicalIF":1.1,"publicationDate":"2025-04-17","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144059165","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Baijintao Sun, Bing Li, Chuan Zhang, Yan Liu, Qing Zhang
{"title":"Efficacy of Thrombin Solution Injection Combined with Rapid Biopsy-Side Down Position Technique in CT-guided Lung Biopsy: A Propensity Score Matching Analysis.","authors":"Baijintao Sun, Bing Li, Chuan Zhang, Yan Liu, Qing Zhang","doi":"10.2174/0115734056342141250320084906","DOIUrl":"https://doi.org/10.2174/0115734056342141250320084906","url":null,"abstract":"<p><strong>Objective: </strong>The objective of this study is to investigate the effect of thrombin solution injection combined with the rapid biopsy-side down position technique on the incidence of pneumothorax in emphysema patients following computed tomography (CT)-guided lung biopsy based on propensity score matching.</p><p><strong>Materials & methods: </strong>A retrospective study was conducted on emphysema patients who underwent CT-guided percutaneous lung biopsy between May 2022 and July 2023. Patients were divided into two groups based on the use of the rapid biopsy-side-down position technique. Propensity score matching was then applied to explore correlations.</p><p><strong>Results: </strong>A total of 212 patients were included in the study. Before propensity score matching, there were no significant differences between Groups A and B in terms of sex, lesion size, puncture path length, or patient positioning in multivariate logistic regression analysis. After matching with a 1:1 ratio, 41 patients were successfully paired. Logistic regression analysis revealed that the rapid biopsy-side down position technique was significantly correlated with a reduced incidence of pneumothorax (p = 0.027), serving as a protective factor.</p><p><strong>Conclusion: </strong>The combination of thrombin solution injection and the rapid biopsy-side down position technique significantly reduces the incidence of pneumothorax in emphysema patients following CT-guided lung biopsy.</p>","PeriodicalId":54215,"journal":{"name":"Current Medical Imaging Reviews","volume":" ","pages":""},"PeriodicalIF":1.1,"publicationDate":"2025-04-09","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144026683","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Short-term MRI Follow-up and Thin-layer PDWI Sequence without Fat Suppression for Detecting Cartilage Loose Bodies: A Case Report.","authors":"Ying Liu, Lei Gao, Junfei Li, Jujia Li, Jian Zhao","doi":"10.2174/0115734056354843250321170055","DOIUrl":"https://doi.org/10.2174/0115734056354843250321170055","url":null,"abstract":"<p><strong>Background: </strong>Osteochondritis Dissecans (OCD) is an idiopathic process and can progress from stable to cartilage fragmentation with the formation of loose bodies in the affected joint capsule. Loose bodies in the knee may wear out the articular cartilage, tendons, and ligaments, leading to a series of problems, such as joint locking, bouncing, joint effusion, and meniscus tear; therefore, early recognition and treatment of intraarticular loose bodies are important to achieve favorable long-term outcomes.</p><p><strong>Case report: </strong>A 49-year-old male presented with a 1-month history of right knee discomfort. The patient underwent a knee MRI scan and was diagnosed with OCD. A short-term MRI follow-up with a thin-layer PDWI sequence without fat suppression detected the cartilage fragments in the knee capsule. Loose body removal, cartilage repair, and microfracture surgery were performed under arthroscopic surgery, and loose bodies of cartilage fragments were removed.</p><p><strong>Conclusion: </strong>Short-term MRI follow-up and thin-layer PDWI sequence without fat suppression are necessary for detecting cartilage loose bodies.</p>","PeriodicalId":54215,"journal":{"name":"Current Medical Imaging Reviews","volume":" ","pages":""},"PeriodicalIF":1.1,"publicationDate":"2025-04-09","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144032394","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}