Mehrad Rokni, Yasser G Abdelhafez, Lorenzo Nardo, Mohammad H Madani
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引用次数: 0
Abstract
Aims: The aim of this study is to assess the identification of incidental myocardial infarction on non-electrocardiogram-gated computed tomographic scans of the chest and its prognostic significance.
Background: The increased utilization and abundance of thoracic computed tomographic (CT) scans have provided a substrate for potential screening purposes.
Objective: The objective of this study was to evaluate the detection of incidental myocardial infarction on routine non-gated thoracic CT performed for noncardiac reasons and its associated major cardiovascular events and survival.
Methods: We retrospectively assessed routine non-gated thoracic CT scans of all consecutive individuals aged 18 or above who underwent thoracic CT scans as outpatients at the University of California Davis from January 2015 to December 2015. We evaluated the presence and location of incidental MI on non-gated thoracic CT and compared major adverse cardiac events (MACE) and overall survival in CT-positive infarct individuals with a CTnegative infarct control group.
Results: We reviewed routine thoracic CT scans of 1157 individuals and identified 12 individuals with incidental MI. The mean age of individuals with infarction was 71.4 ± 14.1 years, and 50% were female. All individuals with incidental MI had coronary calcification. Individuals with incidental MI had a higher rate of MACE endpoint (92% vs. 28%, p=0.0001), number of MACE events (1.1 vs. 0.3, p<0.001), and lower overall survival (median survival of 67 months vs. not reached, p=0.023) compared with age and sex-matched controls without incidental MI.
Conclusion: Although small in number relative to the total number of individuals evaluated, subjects with incidental MI on routine non-gated thoracic CT scans have worse cardiovascular outcomes and survival compared with controls without infarction. This study highlights the potential opportunistic screening utility of routine thoracic CTs, which could lead to improved risk stratification and intervention.
期刊介绍：
Current Medical Imaging Reviews publishes frontier review articles, original research articles, drug clinical trial studies and guest edited thematic issues on all the latest advances on medical imaging dedicated to clinical research. All relevant areas are covered by the journal, including advances in the diagnosis, instrumentation and therapeutic applications related to all modern medical imaging techniques.
The journal is essential reading for all clinicians and researchers involved in medical imaging and diagnosis.
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