Current Medical Imaging Reviews最新文献

{"title":"Reconstruction of Heart-related Imaging from Lung Electrical Impedance Tomography Using Semi-Siamese U-Net.","authors":"Yen-Fen Ko, Yue-Der Lin, Po-Lan Su","doi":"10.2174/0115734056408077250610070821","DOIUrl":"https://doi.org/10.2174/0115734056408077250610070821","url":null,"abstract":"<p><strong>Introduction: </strong>Electrical Impedance Tomography (EIT) is widely used for bedside ventilation monitoring but is limited in reconstructing cardiac-related signals due to the dominance of lung impedance changes. This study aims to reconstruct heart-related impedance imaging from lung EIT using a novel semi-Siamese U-Net architecture.</p><p><strong>Methods: </strong>A deep learning model was developed with a shared encoder and two decoders designed to segment lung and heart regions independently. The model was trained and validated on FEM-based EIT simulations and tested on real human EIT data. A weighted binary cross-entropy loss was applied to emphasize cardiac-related learning.</p><p><strong>Results: </strong>The model achieved a Dice coefficient >0.99 and MAE <0.1% on simulation data. It successfully separated lung and heart regions on human EIT frames without additional fine-tuning, demonstrating strong generalization capacity.</p><p><strong>Discussion: </strong>These findings reveal that the semi-Siamese U-Net can overcome signal dominance and improve cardiac-related EIT reconstruction. However, promising results are currently limited to qualitative evaluation of real data and simulation-based training.</p><p><strong>Conclusion: </strong>The proposed method offers a potential pathway for simultaneous lung-heart monitoring in ICU settings. Future work will focus on clinical validation and real-time implementation.</p>","PeriodicalId":54215,"journal":{"name":"Current Medical Imaging Reviews","volume":" ","pages":""},"PeriodicalIF":1.1,"publicationDate":"2025-07-02","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144561959","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"The Dark Corner of the Pituitary Gland: A Case Report and Literature Review of Primary Melanocytoma.","authors":"Jiajing Ni, Jianhua Wang","doi":"10.2174/0115734056359260250623115500","DOIUrl":"https://doi.org/10.2174/0115734056359260250623115500","url":null,"abstract":"<p><strong>Background: </strong>Primary pituitary melanocytoma, an exceedingly rare tumor, may resemble pituitary adenoma with apoplexy owing to its heterogeneous melanin concentration and possible hemorrhagic events. An accurate diagnosis of melanocytoma is, therefore, essential.</p><p><strong>Case presentation: </strong>We present a case of a 31-year-old female patient who exhibited a progressively worsening headache that commenced one month prior. MRI showed a significantly enlarged sella turcica with a gourd-shaped lesion that had a mixture of short T1 and T2 signals. In conjunction with the MRI findings, CT scans, both non-contrast and contrast-enhanced, revealed a circular, dense region in the sellar area, exhibiting heightened enhancement post-contrast administration. Subsequently, this patient was scheduled for endoscopic transnasal skull base tumor resection and skull base reconstruction. Later, histopathological assessment showed red-S-100 (+), red-melanin A (+), red-KI-67 (+5%), red-melanoma (+), P53 (+), red-P53 (+) and Ki-67 (+) and suggested an intermediate-grade melanocytoma, positioning this lesion between benign and malignant on the spectrum of melanocytic neoplasms.</p><p><strong>Conclusion: </strong>This case report evaluated the presentation, key imaging findings, and histopathological features that help differentiate primary melanocytoma from other tumors and discussed key management and prognostic considerations following diagnosis.</p>","PeriodicalId":54215,"journal":{"name":"Current Medical Imaging Reviews","volume":" ","pages":""},"PeriodicalIF":1.1,"publicationDate":"2025-06-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144546156","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Relationshıp between Condylar and Ramal Asymmetrıes and Abo and Rh Blood Groups.","authors":"Mehmet Emrah Polat, Halil Ibrahim Durmus, Mehmet Gul","doi":"10.2174/0115734056378135250618150104","DOIUrl":"https://doi.org/10.2174/0115734056378135250618150104","url":null,"abstract":"<p><strong>Objective: </strong>The association between ABO and Rh blood groups and diseases is an intriguing topic that continues to be studied, but their potential influence on mandibular asymmetry has not been explored. Temporomandibular joint (TMJ) disorders are multifactorial, and subtle anatomical variations may be linked to genetic predispositions. Our study aims to investigate the relationship between ABO and Rh blood groups and mandibular condylar and ramal asymmetries in a healthy adult Turkish population.</p><p><strong>Materials and methods: </strong>This study included 149 adult patients (67 males, 82 females) who had no history of systemic diseases, craniofacial deformities, or TMJ-related complaints. Asymmetry was assessed in panoramic radiographic images using a formula developed in a previous study. The chi-square and Kruskal-Wallis tests were used to analyze differences among ABO groups while the Mann-Whitney U test was used for Rh groups.</p><p><strong>Results: </strong>No significant difference was found in terms of gender distribution, Rh factor or age between ABO or Rh groups. However, there was a significant difference in condylar asymmetry index (CAI) between ABO groups (p < 0.05). Pairwise comparisons revealed that individuals with AB blood type exhibited significantly higher CAI values compared to those with B blood type. No statistically significant differences in asymmetry indices were observed between Rh groups.</p><p><strong>Conclusion: </strong>The findings of our study indicate the existence of a significant relationship between blood groups and asymmetry indices in a healthy population. The significant differences in condylar asymmetry between AB and B blood groups indicate a possible association between blood type and mandibular anatomical variations, rather than a causal relationship. Further studies are needed to confirm these findings and to understand the underlying mechanisms of the relationship between blood groups and mandibular asymmetry.</p>","PeriodicalId":54215,"journal":{"name":"Current Medical Imaging Reviews","volume":" ","pages":""},"PeriodicalIF":1.1,"publicationDate":"2025-06-24","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144546155","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Gd-EOB-DTPA-Enhanced Magnetic Resonance Imaging for Assessing Liver Function in Primary Biliary Cholangitis.","authors":"Zhengjun Li, Fan Zhang, Weiting Lu, Chao Lu, Zheng Yuan, Zhongqiu Wang","doi":"10.2174/0115734056379090250611073434","DOIUrl":"https://doi.org/10.2174/0115734056379090250611073434","url":null,"abstract":"<p><strong>Introduction: </strong>This study aimed to detect the performance of gadolinium ethoxybenzyl diethylenetriamine pentaacetic acid (Gd-EOB-DTPA)-enhanced magnetic resonance imaging (MRI) for assessing primary biliary cholangitis (PBC).</p><p><strong>Methods: </strong>Seventy-five patients with PBC were included in this prospective study. Shear wave elastography (SWE) and Gd-EOB-DTPA-enhanced MRI were conducted, and then the signal intensity ratio (SIR) and contrast enhancement index (CEI) in different phases, including portal venous phase (PVP), equilibrium phase (EP), and hepatobiliary phase (HBP), were calculated. Afterward, the results were compared with Child-Pugh grading and non-invasive liver fibrosis models using the Kruskal-Wallis H test or Chi-squared test. The area under the curve (AUC) was applied to evaluate the diagnostic performance of SIR_HBP, CEI_HBP, and SWE across different Child-Pugh grades.</p><p><strong>Results: </strong>SWE (p<0.001), SIR _HBP (p<0.001), CEI_HBP (p<0.001), APRI (p=0.002), and FIB-4(p<0.001) showed significant differences in different Child-Pugh grades. Statistically significant differences were found in SIRHBP (p=0.005), CEI_HBP (p=0.010), and FIB-4 (p=0.001) of different SWE levels. For the diagnosis of Child-Pugh C, the AUC of SWE, SIR_HBP, and CEI_HBP were 0.889, 0.778, and 0.761, respectively. Correspondingly, the sensitivity was 75.0%, 64.4%, and 54.2%, and the specificity was 94.9%, 100%, and 100%, respectively. For the diagnosis of Child-Pugh B+C, the AUC of SWE, SIR_HBP, and CEI_HBP were 0.919, 0.809, and 0.814, respectively.</p><p><strong>Discussion: </strong>Our study confirmed that Gd-EOB-DTPA-enhanced MRI is an effective and objective method for assessing liver function in patients with PBC.</p><p><strong>Conclusion: </strong>SIR_HBP and CEI_HBP could be regarded as a novel imaging biomarker to evaluate liver function. Gd-EOB-DTPA-enhanced MRI and SWE outperformed serum-based models in sensitivity and specificity, strengthening the value of imaging in clinical decision-making.</p>","PeriodicalId":54215,"journal":{"name":"Current Medical Imaging Reviews","volume":" ","pages":""},"PeriodicalIF":1.1,"publicationDate":"2025-06-23","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144546154","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Efficacy and Related Factors of Ultrasound-guided Lauromacrogol Injection in Treating Symptomatic Hepatic Cysts with a Diameter of <10cm: A Retrospective Study.","authors":"Qingyin Fu, Bin Hu, Jixian Lin, Qiping Liu, Tonghui Yang, Qiong Chen","doi":"10.2174/0115734056356792250610102812","DOIUrl":"https://doi.org/10.2174/0115734056356792250610102812","url":null,"abstract":"<p><strong>Aims: </strong>This study aimed to retrospectively analyze the curative effect and influencing factors of lauromacrogol in the treatment of symptomatic hepatic cysts of <10 cm.</p><p><strong>Methods: </strong>In this study, a total of 51 patients with symptomatic hepatic cysts (maximum diameter ranging from 5 cm to 10 cm) were included. Polycystic Liver Disease Questionnaire (PLD-Q) was used to evaluate the symptoms of patients prior to treatment. The patients were followed up at 1, 3, 6, and 12 months after treatment. At the 12-month follow-up, patients were asked to fill out the PLD-Q to assess their symptoms. The improvement rate of patients' symptoms was evaluated using a 5-point Likert scale (worse, 1; slight difference, 2; roughly the same, 3; good, and 4; better, 5. Volume reduction rate (VRR) was calculated by measuring the volume of the cyst cavity via ultrasound. Treatment success at the 12-month follow-up was determined using two criteria: symptom improvement and changes in cyst volume. Symptom improvement was assessed using a Likert Scale, with a score greater than 3 points indicating significant improvement. Additionally, a volume reduction rate (VRR) of 50% or more in cyst size (VRR ≥ 50%) was considered an effective treatment outcome. The relationship between the clinical factors and the ultrasonographic manifestations of hepatic cysts, including the initial maximum diameter of the cyst (measured using ultrasound before operation), the initial volume of the cyst, and the formation of septa after sclerosis of the cyst, was analyzed.</p><p><strong>Results: </strong>All patients completed at least 12 months of follow-up. After a 12-month follow-up, the effective and ineffective rates were 96.1% (49/51) and 3.9% (2/51), respectively. The logistic regression univariate analysis showed significant differences in the initial cyst volume (p = 0.001), the initial maximum diameter of the cyst (p = 0.005), and the interval formation after cyst sclerosis (p = <0.001) between VRR ≥ 50% and VRR < 50%. Logistic regression analysis demonstrated that septa formation after cyst sclerosis was an independent factor related to treatment failure, with an odds ratio of 3.246 (95% confidence interval, 0.784-4.148).</p><p><strong>Conclusion: </strong>Lauromacrogol is an effective method for hepatic cyst treatment. Septa formation after cyst sclerosis is an independent factor related to ineffective treatment.</p>","PeriodicalId":54215,"journal":{"name":"Current Medical Imaging Reviews","volume":" ","pages":""},"PeriodicalIF":1.1,"publicationDate":"2025-06-23","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144546151","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Low-Field MRI: A Paradigm Shift in Medical Imaging.","authors":"Ayush Dogra","doi":"10.2174/0115734056397346250609162719","DOIUrl":"https://doi.org/10.2174/0115734056397346250609162719","url":null,"abstract":"","PeriodicalId":54215,"journal":{"name":"Current Medical Imaging Reviews","volume":" ","pages":""},"PeriodicalIF":1.1,"publicationDate":"2025-06-20","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144509426","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Optimised Convolution Layers of DnCNN Using Vedic Multiplier and Hyperparameter Tuning in Cancer Detection on Field Programmable Gate Array.","authors":"S Roobini Priya, Prema Vanaja Ranjan, Shanker Nagalingam Rajediran","doi":"10.2174/0115734056400656250616073019","DOIUrl":"https://doi.org/10.2174/0115734056400656250616073019","url":null,"abstract":"<p><strong>Introduction: </strong>Recently, deep learning (DL) algorithms use Arithmetic Units (AU) in CPU/GPU hardware for processing images/data. AU operates in fixed precision and limits the representation of weights and activations in DL. The problem leads to quantization errors, which reduce accuracy during cancer cell segmentation.</p><p><strong>Methods: </strong>In this study, arithmetic multiplication in convolution layers is replaced with Vedic multiplication in the proposed DnCNN algorithm. Next, Vedic multiplication-based convolution layers in the DnCNN architecture are optimized using POA (Pelican Optimization Algorithm), and the resulting POA-DnCNN is implemented on an FPGA device for breast cancer detection, segmentation, and classification of benign and malignant breast lesions.</p><p><strong>Discussion: </strong>In the convolution layer of DnCNN, floating-point operations are performed through the Hybrid-Vedic (HV) multiplier called 'CUTIN,' which is the combination of <i>Urdhva Tryambakam</i> and <i>Nikhilam Sutra</i> with the upasutra '<i>Anurupyena</i>.' Larger image sizes increase processor size and gate count.</p><p><strong>Results: </strong>The proposed HV-FPGA-based breast cancer detection system, employing Vedic multiplication in the convolution layers of DnCNN and hyperparameters optimized by POA, detects stages of breast cancer with an accuracy of 96.3%, precision of 94.54%, specificity of 92.37%, F-score of 93.56%, IoU of 94.78%, and DSC of 95.45%, outperforming existing methods.</p><p><strong>Conclusion: </strong>The proposed CUTIN multiplier uses a CSA (carry save adder) with simplified sum-carry generation logic (CSCGL), achieving lower area-delay, high speed, and improved precision.</p>","PeriodicalId":54215,"journal":{"name":"Current Medical Imaging Reviews","volume":" ","pages":""},"PeriodicalIF":1.1,"publicationDate":"2025-06-20","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144509427","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"The Clinical Significance of Femoral and Tibial Anatomy for Anterior Cruciate Ligament Injury and Reconstruction.","authors":"Fong Fong Liew, Junqing Liang","doi":"10.2174/0115734056361050250605052447","DOIUrl":"https://doi.org/10.2174/0115734056361050250605052447","url":null,"abstract":"<p><p>The anterior cruciate ligament (ACL) is a crucial stabilizer of the knee joint, and its injury risk and surgical outcomes are closely linked to femoral and tibial anatomy. This review focuses on current evidence on how skeletal parameters, such as femoral intercondylar notch morphology, tibial slope, and insertion site variations-influence ACL biomechanics. A narrowed or concave femoral notch raises the risk of impingement, while a higher posterior tibial slope makes anterior tibial translation worse, which increases ACL strain. Gender disparities exist, with females exhibiting smaller notch dimensions, and hormonal fluctuations may contribute to ligament laxity. Anatomical changes that come with getting older make clinical management even harder. Adolescent patients have problems with epiphyseal growth, and older patients have to deal with degenerative notch narrowing and lower bone density. Preoperative imaging (MRI, CT, and 3D reconstruction) enables precise assessment of anatomical variations, guiding individualized surgical strategies. Optimal femoral and tibial tunnel placement during reconstruction is vital to replicate native ACL biomechanics and avoid graft failure. Emerging technologies, including AI-driven segmentation and deep learning models, enhance risk prediction and intraoperative precision. Furthermore, synergistic factors, such as meniscal integrity and posterior oblique ligament anatomy, need to be integrated into comprehensive evaluations. Future directions emphasize personalized approaches, combining advanced imaging, neuromuscular training, and artificial intelligence to optimize prevention, diagnosis, and rehabilitation. Addressing age-specific challenges, such as growth plate preservation in pediatric cases and osteoarthritis management in the elderly, will improve long-term outcomes. Ultimately, a nuanced understanding of skeletal anatomy and technological integration holds promise for reducing ACL reinjury rates and enhancing patient recovery.</p>","PeriodicalId":54215,"journal":{"name":"Current Medical Imaging Reviews","volume":" ","pages":""},"PeriodicalIF":1.1,"publicationDate":"2025-06-19","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144477847","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Development of a Radiomic-clinical Nomogram for Prediction of Survival in Patients with Nasal Extranodal Natural Killer/T-cell Lymphoma.","authors":"Limin Chen, Zhao Wang, Xiaojie Fang, Mingjie Yu, Haimei Ye, Lujun Han, Ying Tian, Chengcheng Guo, Huang He","doi":"10.2174/0115734056319914250605053257","DOIUrl":"https://doi.org/10.2174/0115734056319914250605053257","url":null,"abstract":"&lt;p&gt;&lt;strong&gt;Introduction: &lt;/strong&gt;An accurate and reliable prognostic model for Nasal Extranodal Natural Killer/T-cell Lymphoma (ENKTL) is critical for survival outcomes and personalized therapy. Currently, there is no Magnetic Resonance Imaging (MRI)- based radiomics analysis in the prognosis model for nasal ENKTL patients.&lt;/p&gt;&lt;p&gt;&lt;strong&gt;Objective: &lt;/strong&gt;We aim to explore the value of MRI-based radiomics signature in the prognosis of patients with nasal ENKTL.&lt;/p&gt;&lt;p&gt;&lt;strong&gt;Methods: &lt;/strong&gt;A total of 159 nasal ENKTL patients were enrolled and divided into a training cohort (n=81) and a validation cohort (n=78) randomly. Radiomics features from pretreatment MRI examination were extracted, respectively. Then two-sample t-test and Least Absolute Shrinkage and Selection Operator (LASSO) regression were used to select the radiomics signatures and establish the Rad-score. Univariate and multivariate Cox proportional hazards regression models were used to investigate the prognostic value of baseline clinical features and establish clinical models. A radiomics nomogram based on the Rad-score and clinical features was constructed to predict Overall Survival (OS). The predictive efficacy of the three models was evaluated in two cohorts.&lt;/p&gt;&lt;p&gt;&lt;strong&gt;Results: &lt;/strong&gt;A total of 1,345 features were extracted from T2-weighted (T2-w) and Contrast-enhanced T1-weighted (CET1-w) images, respectively, and 1,037 features with Intraclass Correlation Coefficient (ICC) &gt;0.7 were selected. Ultimately, 20 features were chosen to construct the Rad-score, which showed a significant association with OS. The C-indexes of the Rad-score were 0.733 (95% confidence interval [CI]: 0.645 to 0.816) and 0.824 (95% CI: 0.766-0.882), respectively, in training and validation cohorts. Through the univariate and multivariate analyses, three independent risk factors for OS were identified: Rad-score (HR: 10.962, 95% CI: 3.417-35.167, P &lt;0.001), lactate dehydrogenase (LDH) level (HR: 3.009, 95% CI: 1.128-8.510, P = 0.028) and distant lymph-node involvement (HR: 2.966, 95% CI: 1.015-8.664, P = 0.047). Patients with distal lymph node involvement and LDH level before treatment were included in the clinical model, which achieved a C-index of 0.707 (95% CI: 0.600-0.814) in the training cohort and 0.635 (95% CI: 0.527-0.743) in the validation cohort. We integrated the Rad-score and clinical variables to establish a radiomics nomogram, which exhibited a satisfactory prediction performance with the C-indexes of 0.849(95% CI: 0.781-0.917) and 0.931(95% CI: 0.882-0.980) in two cohorts, respectively. The radiomics nomogram was more accurate in predicting OS in patients with nasal ENKTL than the other two models. Based on the radiomics nomogram, patients were categorized into low-risk and high-risk groups in two cohorts (P all &lt; 0.05). The high-risk group defined by this nomogram exhibited a shorter OS.&lt;/p&gt;&lt;p&gt;&lt;strong&gt;Conclusion: &lt;/strong&gt;The Rad-score was significantly correlated with OS for ","PeriodicalId":54215,"journal":{"name":"Current Medical Imaging Reviews","volume":" ","pages":""},"PeriodicalIF":1.1,"publicationDate":"2025-06-19","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144477846","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Navigating the Diagnostic Maze: A Case Report and Narrative Review of Reversible Cerebral Vasoconstriction Syndrome.","authors":"Xuefan Yao, Yuzhe Li, Aini He, Benke Zhao, Wei Sun, Xiao Wu, Haiqing Song","doi":"10.2174/0115734056366051250604054327","DOIUrl":"10.2174/0115734056366051250604054327","url":null,"abstract":"<p><strong>Introduction: </strong>Reversible cerebral vasoconstriction syndrome (RCVS) is a condition characterized by thunderclap headaches, which are sudden and severe headaches that peak within a few seconds. These headaches present diagnostic difficulties due to their diversity and low specificity, often leading to misdiagnoses and patient dissatisfaction.</p><p><strong>Case presentation: </strong>We present the case of a 52-year-old woman with a 10-day history of recurrent thunderclap headaches. Initial imaging revealed no abnormalities, but she experienced further episodes of thunderclap headaches during hospitalization. Subsequent neurovascular imaging revealed multiple intracranial stenoses with a \"string of beads\" appearance, confirming the diagnosis of reversible cerebral vasoconstriction syndrome. She was treated with nimodipine, and most symptoms had resolved upon discharge, with no recurrence of headache reported during a 3-month follow-up.</p><p><strong>Discussion: </strong>Prior reviews on reversible cerebral vasoconstriction syndrome predominantly emphasized isolated symptoms or advanced neuroimaging findings, offering limited applicability in primary care services. More attention should be given to identifying clinical manifestations warranting heightened reversible cerebral vasoconstriction syndrome suspicion.</p><p><strong>Conclusion: </strong>Early recognition of reversible cerebral vasoconstriction syndrome counts in primary care services. We proposed a revised diagnostic routine that begins with clinical suspicion prompted by typical manifestations, like recurrent thunderclap headaches, female sex, and specific triggers, and recommends advanced neurovascular imaging when accessible. Extreme headache severity or deviation from prior migraine patterns should raise suspicion for reversible cerebral vasoconstriction syndrome, while diagnostic consideration should still remain in patients with transient neurological deficits, seizures, or cerebrovascular events.</p>","PeriodicalId":54215,"journal":{"name":"Current Medical Imaging Reviews","volume":" ","pages":""},"PeriodicalIF":1.1,"publicationDate":"2025-06-17","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144334420","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}