Nano Letters最新文献_第7页

X-ray-Triggered Nanoadjuvant Enabling Spatiotemporal Immunometabolic Modulation for Pyroptosis-Enhanced Radiotherapy x射线触发的纳米佐剂对热疗增强放疗的时空免疫代谢调节

IF 9.1 1区材料科学

Nano Letters Pub Date : 2026-11-04 Epub Date: 2026-10-23 DOI: 10.1021/acs.nanolett.6c04189

Wenjun Liu, Yushi Chen, Yanmin Xiao, Jin Gao, Shanwen Hu, Lanlan Chen, Jibin Song, Huanghao Yang

{"title":"X-ray-Triggered Nanoadjuvant Enabling Spatiotemporal Immunometabolic Modulation for Pyroptosis-Enhanced Radiotherapy","authors":"Wenjun Liu, Yushi Chen, Yanmin Xiao, Jin Gao, Shanwen Hu, Lanlan Chen, Jibin Song, Huanghao Yang","doi":"10.1021/acs.nanolett.6c04189","DOIUrl":"10.1021/acs.nanolett.6c04189","url":null,"abstract":"Radiotherapy efficacy is limited by an immunosuppressivetumormicroenvironment (TME). Current immunometabolic strategies using nonselectiveinhibitors or exogenous stimulus-activated nanomedicines suffer fromoff-target toxicity, insufficient antitumor responses, and proceduralcomplexity. Herein, we developed PLG@OMVs-VP, an X-ray-activatablenanoadjuvant, to remodel the immunosuppressive TME and amplify theradiotherapy efficacy. PLG@OMVs-VP comprises outer membrane vesicles(OMVs) modified with verteporfin (VP) and an indoleamine 2,3-dioxygenaseinhibitor (NLG-919) via a PEGylated singlet oxygen (1O2)-cleavable linker. Upon X-ray radiation, VP absorbs X-raysand generates 1O2, which not only induces immunogenictumor cell death via radiodynamic therapy but also triggers the selectiverelease of NLG-919 for immunometabolic regulation. Moreover, the intrinsiclipopolysaccharide on OMVs activates pyroptosis, further enhancingthe tumor immunogenicity. This strategy integrates pyroptosis-inducedimmunogenicity, radiodynamic therapy, and spatially controlled immunometabolicregulation, synergistically alleviating TME immunosuppression andeliciting antitumor immunity in both primary and distant tumors. ThisX-ray-activatable nanoplatform enables TME remodeling and an enhancedradiotherapy.","PeriodicalId":53,"journal":{"name":"Nano Letters","volume":"26 43","pages":"15146–15158"},"PeriodicalIF":9.1,"publicationDate":"2026-11-04","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"149241851","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"材料科学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Divalent Cations Induce Rigid and Compact Structures in Underwound DNA 二价阳离子诱导下缠绕DNA的刚性和致密结构

IF 10.8 1区材料科学

Nano Letters Pub Date : 2026-11-04 DOI: 10.1021/acs.nanolett.6c03884

Aleksander Klimczyk,Dorothy Aboagye-Mensah,Graeme A. King

引用次数: 0

Structure-Dependent Chemical Order Modification in Strained Alloy Nanoparticles 结构相关的化学有序修饰纳米合金

IF 9.1 1区材料科学

Nano Letters Pub Date : 2026-11-04 Epub Date: 2026-09-11 DOI: 10.1021/acs.nanolett.6c03772

Yue Wang, Zibo Chen, Evropi Toulkeridou, Joseph Kioseoglou, Panagiotis Grammatikopoulos

{"title":"Structure-Dependent Chemical Order Modification in Strained Alloy Nanoparticles","authors":"Yue Wang, Zibo Chen, Evropi Toulkeridou, Joseph Kioseoglou, Panagiotis Grammatikopoulos","doi":"10.1021/acs.nanolett.6c03772","DOIUrl":"10.1021/acs.nanolett.6c03772","url":null,"abstract":"Alloy nanoparticles (nanoalloys) exhibit tunable physicochemicalproperties that depend sensitively on atomic arrangement. While mosttheoretical studies consider nanoalloys in a vacuum, practical systemsare typically supported, where strong cluster–substrate interactionscan introduce significant lattice strain. Here, we investigate strainas a control parameter for chemical ordering in bimetallic nanoalloysusing atomistic simulations. Imposing controlled strain through animplicit anchored interface, we probe the response of NiPt nanoparticleswith distinct structural motifs. For truncated-octahedral particles,chemical ordering remains remarkably robust even under large strains,indicating that intrinsic thermodynamic preferences dominate. Conversely,icosahedral nanoparticles exhibit pronounced strain-induced chemicalredistribution with a significant increase in surface Ni concentrationunder tensile strain, attributed to the combined effects of intrinsicgeometric frustration and a high fraction of undercoordinated sites.Our results demonstrate that strain can selectively modulate chemicalordering in a structure-dependent manner, establishing a general frameworkfor understanding strain-induced chemical ordering in nanoalloys.","PeriodicalId":53,"journal":{"name":"Nano Letters","volume":"26 43","pages":"15022–15029"},"PeriodicalIF":9.1,"publicationDate":"2026-11-04","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148933819","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"材料科学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Deep-Learning-Driven Dual Sensors Based on Single-Trapped Upconverting Particles 基于单捕获上转换粒子的深度学习驱动双传感器

IF 9.1 1区材料科学

Nano Letters Pub Date : 2026-11-04 Epub Date: 2026-10-20 DOI: 10.1021/acs.nanolett.6c03652

Óscar Pérez-Benito, J. Ignacio Echavarría, Javier Hernandez-Rueda

{"title":"Deep-Learning-Driven Dual Sensors Based on Single-Trapped Upconverting Particles","authors":"Óscar Pérez-Benito, J. Ignacio Echavarría, Javier Hernandez-Rueda","doi":"10.1021/acs.nanolett.6c03652","DOIUrl":"10.1021/acs.nanolett.6c03652","url":null,"abstract":"Upconverting lanthanide-dopedparticles are widely usedas nanoscaletemperature sensors, particularly in biological and photonic environments.However, extending their functionality to simultaneously measure temperatureand light intensity remains a challenge, as the luminescent responseis highly sensitive to both the environment composition and its temperature.In this work, we combine deep-learning methods with large-scale spectraldata sets to investigate the reliability of Er/Yb-doped particlesto function as dual sensors. Spectral data are collected from singleparticles levitating in vacuum and ensembles of particles in application-relevantwet and dry media. Although traditional ratiometric methods reliablyretrieve temperature irrespective of the environment and specificexperimental apparatus, they fail to disentangle the complex dependenciesneeded for dual sensing. Our trained models overcome these limitations,accurately predicting both temperature and laser power despite environmentalvariability. This approach opens a new route toward robust, data-drivensensing with upconverting particles in complex or fluctuating conditions.","PeriodicalId":53,"journal":{"name":"Nano Letters","volume":"26 43","pages":"14987–14992"},"PeriodicalIF":9.1,"publicationDate":"2026-11-04","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"149218894","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"材料科学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Intra- and Interlayer Excitonic Fine Structure of the Two-Dimensional Perovskite (PEA)2PbI4 二维钙钛矿（PEA）2PbI4的层内和层间激子精细结构

IF 9.1 1区材料科学

Nano Letters Pub Date : 2026-11-04 Epub Date: 2026-10-20 DOI: 10.1021/acs.nanolett.6c01957

Patrick Grenzer, Fabian Lie, Klaus H. Eckstein, Tobias Hertel, Linn Leppert

{"title":"Intra- and Interlayer Excitonic Fine Structure of the Two-Dimensional Perovskite (PEA)2PbI4","authors":"Patrick Grenzer, Fabian Lie, Klaus H. Eckstein, Tobias Hertel, Linn Leppert","doi":"10.1021/acs.nanolett.6c01957","DOIUrl":"10.1021/acs.nanolett.6c01957","url":null,"abstract":"Two-dimensional halide perovskites host strongly boundexcitonswhose fine structure governs polarization selection rules and radiativerecombination, yet spectral features in phenethylammonium lead iodide((PEA)2PbI4) remain controversially assigned.Here, polarization-resolved low-temperature photoluminescence (PL)combined with first-principles G0W0+BSE calculations probes the intralayer andinterlayer excitonic fine structure of this Ruddlesden–Popperperovskite. The low-energy multiplet is consistent with the intralayerexcitonic fine structure governed by electron–hole exchange,crystal symmetry, and layer inequivalence in the two-layer unit cell,without requiring Rashba effects or exciton–polaron mechanismsas its primary origin. The weak doublet about 40 meV higher is bestaccounted for by interlayer excitons based on its energetics, splitting,and real-space character. Distortion-induced mixing of interlayerexcitons with bright intralayer excitons provides a plausible explanationfor the observed interlayer PL intensities and nearly orthogonal polarizations.These results support a layer-resolved excitonic picture encompassingboth intralayer and interlayer states in (PEA)2PbI4.","PeriodicalId":53,"journal":{"name":"Nano Letters","volume":"26 43","pages":"14821–14828"},"PeriodicalIF":9.1,"publicationDate":"2026-11-04","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"149221737","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"材料科学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Photoinduced Surface Reconstruction Strategy for Enhancing AgBiS2 Quantum Dot Solar Cells 增强AgBiS2量子点太阳能电池的光致表面重建策略

IF 9.1 1区材料科学

Nano Letters Pub Date : 2026-11-04 Epub Date: 2026-10-21 DOI: 10.1021/acs.nanolett.6c03987

Qixuan Zhong, Ruchao Gong, Junxiao Zhang, Lei Xu, Jingzhi Shang, Shuguang Wang, Muhan Cao, Jinxing Chen, Lichen Zhao, Qiao Zhang, Jianpu Wang

{"title":"Photoinduced Surface Reconstruction Strategy for Enhancing AgBiS2 Quantum Dot Solar Cells","authors":"Qixuan Zhong, Ruchao Gong, Junxiao Zhang, Lei Xu, Jingzhi Shang, Shuguang Wang, Muhan Cao, Jinxing Chen, Lichen Zhao, Qiao Zhang, Jianpu Wang","doi":"10.1021/acs.nanolett.6c03987","DOIUrl":"10.1021/acs.nanolett.6c03987","url":null,"abstract":"Silver bismuth sulfide (AgBiS2) quantum dots(QDs) arepromising candidates for eco-friendly solution-based solar cells.However, structural defects in QDs hinder high efficiency. Controllablesynthesis of AgBiS2 QDs remains challenging, often yieldingcrystals with surface and lattice defects that promote nonradiativerecombination. Improving AgBiS2 QD quality before filmformation is crucial, as synthesis-related imperfections often persistin devices and inherently limit effective passivation later on. Thisstudy presents a photoinduced surface reconstruction method for AgBiS2 QDs that achieves nearly perfect ionic ordering with lowerlattice strain, leading to denser films and better band alignmentwith charge layers than the initial AgBiS2 QDs. Correspondingsolar cells achieve a power conversion efficiency of 9.71%, exceeding8.16% for untreated solar cells. By enhancing AgBiS2 QDquality at the source rather than relying solely on downstream passivation,this approach offers a complementary pathway to high-performance QDsolar cells.","PeriodicalId":53,"journal":{"name":"Nano Letters","volume":"26 43","pages":"15080–15087"},"PeriodicalIF":9.1,"publicationDate":"2026-11-04","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"149226576","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"材料科学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Activation-Free Liquid Metal Bioelectronics Enabled by a Reconfigurable Island-Bridge Nanoarchitecture for Machine-Learning-Assisted Activity Recognition 无激活液态金属生物电子学由可重构岛桥纳米结构实现，用于机器学习辅助活动识别

IF 9.1 1区材料科学

Nano Letters Pub Date : 2026-11-04 Epub Date: 2026-10-22 DOI: 10.1021/acs.nanolett.6c03097

Yunpeng Huang, Haitao Huang, Haoxuan Zhu, Yidong Peng, Haoran Liu, Kangjia Geng, Yanqing Gu, Jiancheng Dong, Biao Zhou

{"title":"Activation-Free Liquid Metal Bioelectronics Enabled by a Reconfigurable Island-Bridge Nanoarchitecture for Machine-Learning-Assisted Activity Recognition","authors":"Yunpeng Huang, Haitao Huang, Haoxuan Zhu, Yidong Peng, Haoran Liu, Kangjia Geng, Yanqing Gu, Jiancheng Dong, Biao Zhou","doi":"10.1021/acs.nanolett.6c03097","DOIUrl":"10.1021/acs.nanolett.6c03097","url":null,"abstract":"Patternable liquid metal particle (LMP) conductors withstableperformance under deformation are highly desirable for wearable electronicsbut remain limited by activation-dependent conductivity and structuralinstability. Here, we report an activation-free conductive ink basedon nickel-coated carbon nanotubes (NiCNTs) and nanoscale LMPs. A solvent-mediatedstabilization strategy suppresses droplet coalescence, yielding uniformlydispersed and stable LMPs. Strong interfacial coupling enabled byhydrogen-bond-assisted adsorption and Ni–Ga alloying promotesthe formation of a dynamically reconfigurable “island-bridge”network, where conductive LMP domains are interconnected by compliantNiCNT bridges. This architecture achieves high electrical conductivity(5.9 × 105 S m–1) without externalactivation and maintains excellent electromechanical stability (4.6× 105 S m–1 at 100% strain) andprintability on various soft substrates. Printed epidermal electrodesenable low-impedance electrocardiogram monitoring over 7 days andsupport machine-learning-assisted activity recognition with accuraciesabove 99%, providing a general strategy for intrinsically conductiveand mechanically resilient soft electronics.","PeriodicalId":53,"journal":{"name":"Nano Letters","volume":"26 43","pages":"14890–14899"},"PeriodicalIF":9.1,"publicationDate":"2026-11-04","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"149230240","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"材料科学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Threefold-Symmetric Te Nanoparticles for Stabilizing Zinc Metal Anodes 用于稳定锌金属阳极的三对称纳米粒子

IF 9.1 1区材料科学

Nano Letters Pub Date : 2026-11-04 Epub Date: 2026-10-24 DOI: 10.1021/acs.nanolett.6c02828

Jiawei Su, ChangChun Fan, Zhuoyuan Li, Weiguang Lan, Guoming Lin, Wenhui Wang, Mingjie Liu

引用次数: 0

Reaction-Programmed Interphase Reconstruction by an Ultrathin Zinc Phosphate Nanofilm for Reversible Lithium Metal Anodes 用超薄磷酸锌纳米膜重建可逆锂金属阳极的反应程序界面

IF 10.8 1区材料科学

Nano Letters Pub Date : 2026-11-04 DOI: 10.1021/acs.nanolett.6c03951

Yihan Meng,Junpeng Li,Xuejian Shi,Teng Ma,Junjie Ba,Yue Wang,Ruqian Lian,Yizhan Wang,Yingjin Wei

引用次数: 0

Physics-Consistent Generative Hologram Design for Multifocal Femtosecond Laser Fabrication 多焦飞秒激光制造的物理一致性生成全息图设计

IF 9.1 1区材料科学

Nano Letters Pub Date : 2026-11-04 Epub Date: 2026-10-19 DOI: 10.1021/acs.nanolett.6c03779

Bowen Chen, Hao Wu, Xiaoxu Rao, Wenji Yang, Zeye Li, Jincheng Ni, Jiawen Li, Dong Wu, Yanlei Hu, Chaowei Wang

{"title":"Physics-Consistent Generative Hologram Design for Multifocal Femtosecond Laser Fabrication","authors":"Bowen Chen, Hao Wu, Xiaoxu Rao, Wenji Yang, Zeye Li, Jincheng Ni, Jiawen Li, Dong Wu, Yanlei Hu, Chaowei Wang","doi":"10.1021/acs.nanolett.6c03779","DOIUrl":"10.1021/acs.nanolett.6c03779","url":null,"abstract":"Multifocal phase holography offers a route to parallelfemtosecondlaser micro- and nanofabrication, but conventional weighted Gerchberg–Saxton(GSW) phase retrieval requires target-specific iterations and doesnot jointly optimize the optical quantities governing exposure quality.Here we introduce PhyFlow, a physics-consistent invertible flow modelthat generates phase-only multifocal holograms from target multifocalpatterns in a single inverse pass. A multiscale invertible backbonelearns target-to-phase correspondence, while differentiable Fourieroptics constraints optimize diffraction efficiency, focal uniformity,and target-shape preservation. Across focal numbers and array scales,PhyFlow matches or surpasses GSW in energy concentration, focal balance,and shape fidelity while reducing per-hologram generation time by98.8%. Optical-field measurements and femtosecond laser writing furthershow improved dot-area consistency, narrower line width distributions,and fewer nontarget written features. PhyFlow therefore connects rapidlearned hologram generation with physically optimized fields and moreuniform parallel fabrication.","PeriodicalId":53,"journal":{"name":"Nano Letters","volume":"26 43","pages":"15030–15038"},"PeriodicalIF":9.1,"publicationDate":"2026-11-04","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"149218888","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"材料科学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0