Nano Letters最新文献_第10页

Quantum-Sized Sb@Au Schottky Heterostructure for Sensitized Radioimmunotherapy 致敏放射免疫治疗的量子级Sb@Au肖特基异质结构

IF 10.8 1区材料科学

Nano Letters Pub Date : 2025-05-17 DOI: 10.1021/acs.nanolett.5c01776

Chuang Shen, Xianghong Niu, Jianwei Chen, Fei Xu, Ming Liu, Yefan Duan, Hongfang Du, Qianshi Shang, Xiuyun Zhang, Ying Zhang, Lixing Weng, Zhimin Luo, Lianhui Wang

{"title":"Quantum-Sized Sb@Au Schottky Heterostructure for Sensitized Radioimmunotherapy","authors":"Chuang Shen, Xianghong Niu, Jianwei Chen, Fei Xu, Ming Liu, Yefan Duan, Hongfang Du, Qianshi Shang, Xiuyun Zhang, Ying Zhang, Lixing Weng, Zhimin Luo, Lianhui Wang","doi":"10.1021/acs.nanolett.5c01776","DOIUrl":"https://doi.org/10.1021/acs.nanolett.5c01776","url":null,"abstract":"Radiodynamic therapy (RDT) holds great potential for overcoming radioresistance and enhancing tumor immunogenicity. However, its efficacy is hindered by limited reactive oxygen species (ROS) generation due to insufficient carrier generation and transfer, which often results in tumor metastasis. Here, we report quantum-sized and narrow-bandgap Sb@Au Schottky heterostructures, namely, Sb@Au nanodots (Sb@Au NDs), to improve ROS generation for sensitizing RDT and inhibiting tumor metastasis. Experimental results and density functional theory calculations show that Sb@Au NDs give narrow bandgap and high Schottky potential barrier for promoting carrier generation and separation under X-ray irradiation, and present rich active sites for improving catalytic performance, leading to abundant ROS generation and significantly amplifying intracellular oxidative stress to enhance RDT. Sb@Au ND-sensitized RDT greatly induces immunogenic cell death and thus promotes CD8+ T cell-mediated systemic immunity, ultimately suppressing tumor metastasis. Our finding highlights the potential of narrow-bandgap Sb@Au NDs as an effective sensitizer for radioimmunotherapy.","PeriodicalId":53,"journal":{"name":"Nano Letters","volume":"152 1","pages":""},"PeriodicalIF":10.8,"publicationDate":"2025-05-17","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144067330","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"材料科学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Ferromagnetism in Two-Dimensional Dysprosium–Platinum Surface Alloy 二维镝-铂表面合金的铁磁性

IF 10.8 1区材料科学

Nano Letters Pub Date : 2025-05-17 DOI: 10.1021/acs.nanolett.5c00262

Marta Przychodnia, Maciej Bazarnik

引用次数: 0

Nanoscale Thermomechanical Coupling Study on the Aging of NASICON-Type Solid Electrolytes nasicon型固体电解质老化的纳米尺度热-机耦合研究

IF 9.6 1区材料科学

Nano Letters Pub Date : 2025-05-17 DOI: 10.1021/acs.nanolett.5c0097110.1021/acs.nanolett.5c00971

Xuyang Wang, Fang Wang, Qingfeng Zhu, Mingqiang Cheng, Chunlin Song, Yingzhi Li, Zhouguang Lu, Hongyun Jin* and Boyuan Huang*,

{"title":"Nanoscale Thermomechanical Coupling Study on the Aging of NASICON-Type Solid Electrolytes","authors":"Xuyang Wang, Fang Wang, Qingfeng Zhu, Mingqiang Cheng, Chunlin Song, Yingzhi Li, Zhouguang Lu, Hongyun Jin* and Boyuan Huang*, ","doi":"10.1021/acs.nanolett.5c0097110.1021/acs.nanolett.5c00971","DOIUrl":"https://doi.org/10.1021/acs.nanolett.5c00971https://doi.org/10.1021/acs.nanolett.5c00971","url":null,"abstract":"Previous investigations on the aging mechanism of solid electrolytes (SEs) predominantly focused on electrochemical and mechanical properties, often overlooking their thermal characteristics. In this study, we introduced scanning thermal microscopy and scanning thermo-ionic microscopy to delve into the microscopic aging process of the Li1.4Al0.4Ti1.6(PO4)3 (LATP) SE assembled with Li metal. Our findings revealed the formation of a Li3Al0.4Ti1.6(PO4)3 secondary phase during cycling. Compared with the unreacted LATP, this secondary phase exhibits a remarkable decrease in thermal conductivity (from 1.72 to 0.63 W m–1 K–1), Young’s modulus (from 117.4 to 31.3 GPa), and ionic activity, while demonstrating an increase in thermal expansion response. These mismatches worsen the interfacial contact, contributing to the formation of cracks and a sharp increase in impedance. To the best of our knowledge, this is the first time that the thermomechanical coupling of SEs has been studied at the nanoscale, underscoring the pivotal impact of the thermal properties on SE degradation.","PeriodicalId":53,"journal":{"name":"Nano Letters","volume":"25 21","pages":"8533–8540 8533–8540"},"PeriodicalIF":9.6,"publicationDate":"2025-05-17","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144146397","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"材料科学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Observation of Atomic-Scale Polar Vortex–Antivortex Pairs in Antiferroelectric PbZrO3 Thin Films 反铁电PbZrO3薄膜中原子尺度极性涡-反涡对的观测

IF 9.6 1区材料科学

Nano Letters Pub Date : 2025-05-17 DOI: 10.1021/acs.nanolett.5c0150610.1021/acs.nanolett.5c01506

Xian-Kui Wei*, Ke Xu, Kaushik Vaideeswaran, Joachim Mayer and Houbing Huang*,

{"title":"Observation of Atomic-Scale Polar Vortex–Antivortex Pairs in Antiferroelectric PbZrO3 Thin Films","authors":"Xian-Kui Wei*, Ke Xu, Kaushik Vaideeswaran, Joachim Mayer and Houbing Huang*, ","doi":"10.1021/acs.nanolett.5c0150610.1021/acs.nanolett.5c01506","DOIUrl":"https://doi.org/10.1021/acs.nanolett.5c01506https://doi.org/10.1021/acs.nanolett.5c01506","url":null,"abstract":"Topological polar structures, in analogy to spin vortices and skyrmions, have received tremendous attention for their fascinating prospects in future device applications. However, in the widely studied ferroelectric-based superlattices, the epitaxial heterointerfaces, yielding desired strain, depolarization, and gradient energies, greatly confine the mobility of the topological solitons. Here, we report observation of polar vortex–antivortex pairs near junctions of antiphase boundaries in antiferroelectric PbZrO3 thin films by using atomic-resolution scanning transmission electron microscopy. Our temporal-resolved lattice analysis reveals that the local strain gradient caused by an incommensurate modulation constructs the smallest topological units reported to date. Our phase-field simulations unveil that the Pb–O vacancy-induced random electric fields account for their three-dimensional formation, and the stimulus of electron-beam irradiation can drive their dynamic migration. The findings offer a new approach to comprehend fundamental physics about antiferroelectricity and the design of functional devices based on topological structures in antiferroelectric thin films.","PeriodicalId":53,"journal":{"name":"Nano Letters","volume":"25 21","pages":"8655–8662 8655–8662"},"PeriodicalIF":9.6,"publicationDate":"2025-05-17","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144146400","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"材料科学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Measurement and Modeling of Electron and Hole Injection Dynamics in Quantum-Dot Light-Emitting Diodes: Quantifying Temperature-Dependent Charge Imbalance 量子点发光二极管中电子和空穴注入动力学的测量和建模：量化温度相关电荷不平衡

IF 9.6 1区材料科学

Nano Letters Pub Date : 2025-05-16 DOI: 10.1021/acs.nanolett.5c0122710.1021/acs.nanolett.5c01227

Tianle Fan, Xitong Zhu, Shuai Chang, Xianchang Yan, Yizheng Jin, Shengye Jin, Boning Wu* and Wenming Tian*,

{"title":"Measurement and Modeling of Electron and Hole Injection Dynamics in Quantum-Dot Light-Emitting Diodes: Quantifying Temperature-Dependent Charge Imbalance","authors":"Tianle Fan, Xitong Zhu, Shuai Chang, Xianchang Yan, Yizheng Jin, Shengye Jin, Boning Wu* and Wenming Tian*, ","doi":"10.1021/acs.nanolett.5c0122710.1021/acs.nanolett.5c01227","DOIUrl":"https://doi.org/10.1021/acs.nanolett.5c01227https://doi.org/10.1021/acs.nanolett.5c01227","url":null,"abstract":"The development of quantum-dot light-emitting diodes (QLEDs) has been hindered by an incomplete understanding of their charge injection dynamics. This study systematically investigates electron–hole injection in red, green, and blue QLEDs using electrically pumped transient absorption and time-resolved electroluminescence technologies. Temperature-dependent measurements between 140 and 298 K reveal weak electron injection enhancement versus strong hole injection improvement as temperature increases. Therefore, lower temperatures exacerbate charge imbalance, increasing electron accumulation in quantum dots during the operation. We develop quantitative models using space-charge-limited current and thermionic emission theories for electron and hole injection, respectively, establishing a universal framework for QLED operation. These findings provide critical insights for optimizing the charge balance and device performance in QLEDs.","PeriodicalId":53,"journal":{"name":"Nano Letters","volume":"25 21","pages":"8564–8570 8564–8570"},"PeriodicalIF":9.6,"publicationDate":"2025-05-16","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144146425","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"材料科学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Casimir Force Control Enabled by 3D Nanostructures 三维纳米结构实现卡西米尔力控制

IF 10.8 1区材料科学

Nano Letters Pub Date : 2025-05-16 DOI: 10.1021/acs.nanolett.5c01101

Calum Shelden, Benjamin Spreng, Joseph L. Garrett, Tahmid S. Rahman, Jongbum Kim, Jeremy N. Munday

引用次数: 0

Precise Oligomer Organization Enhanced Electrostatic Interactions for Efficient Cell Membrane Binding. 精确的低聚物组织增强了有效细胞膜结合的静电相互作用。

IF 10.8 1区材料科学

Nano Letters Pub Date : 2025-05-16 DOI: 10.1021/acs.nanolett.5c00651

Yuanyuan Zhao,Yiqian Luo,Yi Chai,Yintung Lam,Yongqing Gong,Ke Chen,Gang Lu,Gang Xia,Yun Chang,Menghao Yang,Yang Xu,John Haozhong Xin

{"title":"Precise Oligomer Organization Enhanced Electrostatic Interactions for Efficient Cell Membrane Binding.","authors":"Yuanyuan Zhao,Yiqian Luo,Yi Chai,Yintung Lam,Yongqing Gong,Ke Chen,Gang Lu,Gang Xia,Yun Chang,Menghao Yang,Yang Xu,John Haozhong Xin","doi":"10.1021/acs.nanolett.5c00651","DOIUrl":"https://doi.org/10.1021/acs.nanolett.5c00651","url":null,"abstract":"Efficient binding of cell membranes onto nanomaterials is essential for biomedical applications such as diagnostics and cellular engineering. We find that fine control over oligomer orientation led to enhanced electrostatic interactions with the cell membrane and improved cell membrane capture. Specifically, we designed polycation oligomers incorporating positively charged imidazole heads and alkyl tails synthesized through the reversible addition-fragmentation chain transfer (RAFT) reaction. These oligomers spontaneously self-assemble through head-to-head π-π interactions, and their spatial arrangement markedly accelerates the interaction with negatively charged cell membranes. Experimental results indicate that these oriented oligomers produce a large decrease in the time required to kill bacteria compared to unmodified nanostructures (3 min versus 100 min). This is attributed to locally concentrated electrostatic attraction, which enhances the attraction between nanostructures and negatively charged cell surfaces. Our findings suggest that molecular orientation control could be a promising approach to enhancing interactions between biomaterials and live cells.","PeriodicalId":53,"journal":{"name":"Nano Letters","volume":"15 1","pages":""},"PeriodicalIF":10.8,"publicationDate":"2025-05-16","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144065776","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"材料科学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Artificial Axon with Dendritic-like Plasticity by Biomimetic Interface Engineering of Anisotropic Two-Dimensional Tellurium 基于各向异性二维碲仿生界面工程的树状可塑性人工轴突

IF 9.6 1区材料科学

Nano Letters Pub Date : 2025-05-16 DOI: 10.1021/acs.nanolett.5c0147810.1021/acs.nanolett.5c01478

Jiwei Chen, Changjian Zhou*, Yingjie Luo, Wenbo Li, Xiankai Lin, Chunlei Zhang, Siyu Liao, Ruolan Wen, Guitian Qiu, Qian Zhang, Jianxian Yi, Wenhan Lei, Lin Wang, Syed Rizwan, Pei Lin and Qijie Liang*,

{"title":"Artificial Axon with Dendritic-like Plasticity by Biomimetic Interface Engineering of Anisotropic Two-Dimensional Tellurium","authors":"Jiwei Chen, Changjian Zhou*, Yingjie Luo, Wenbo Li, Xiankai Lin, Chunlei Zhang, Siyu Liao, Ruolan Wen, Guitian Qiu, Qian Zhang, Jianxian Yi, Wenhan Lei, Lin Wang, Syed Rizwan, Pei Lin and Qijie Liang*, ","doi":"10.1021/acs.nanolett.5c0147810.1021/acs.nanolett.5c01478","DOIUrl":"https://doi.org/10.1021/acs.nanolett.5c01478https://doi.org/10.1021/acs.nanolett.5c01478","url":null,"abstract":"Spiking neural network (SNN) hardware relies on implicit assumptions that prioritize dendritic/synaptic learning above axon/synaptic concerns, compromising performances in signal capacity, accuracy, and compactness of SNN systems. Herein, we develop an artificial axon by utilizing the heterogeneity and interface state tunability in anisotropic two-dimensional (2D) tellurium (Te). By operating a multiterminal axon under the bioelectricity level, the device achieved neuron-like heterogeneous axon dynamics expansion (∼258%). An excellent dendritic-like tunability (∼197%) exhibits gain on the axons. The synergistic axon–dendrite optimization device exhibits 5-bit programmable conductance, signal filtering, and input enhancing. The accuracy of recognizing data sets based on the SNN algorithm demonstrates efficient optimization (5.2% higher accuracy) of networks by the device features, especially in the case of performing image preprocessing. This artificial neuron solution with anisotropic 2D materials utilizing biomimetic interface engineering provides a universal strategy for compact, high-precision parallel architecture of SNN hardware.","PeriodicalId":53,"journal":{"name":"Nano Letters","volume":"25 21","pages":"8619–8627 8619–8627"},"PeriodicalIF":9.6,"publicationDate":"2025-05-16","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144146383","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"材料科学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Stabilizing Gold Nanotetrapods via in Situ Polymerization for Superior Photoacoustic and Photothermal Applications. 通过原位聚合稳定金纳米四足体用于优越的光声和光热应用。

IF 10.8 1区材料科学

Nano Letters Pub Date : 2025-05-16 DOI: 10.1021/acs.nanolett.5c01764

Jing Wang,Huazhen Chen,Dazhi Chen,Yuchao Luo,Zhi-Li Shen,Ning-Ning Zhang,Biqin Dong,Wenjing Tian,Kun Liu,Bin Xu

{"title":"Stabilizing Gold Nanotetrapods via in Situ Polymerization for Superior Photoacoustic and Photothermal Applications.","authors":"Jing Wang,Huazhen Chen,Dazhi Chen,Yuchao Luo,Zhi-Li Shen,Ning-Ning Zhang,Biqin Dong,Wenjing Tian,Kun Liu,Bin Xu","doi":"10.1021/acs.nanolett.5c01764","DOIUrl":"https://doi.org/10.1021/acs.nanolett.5c01764","url":null,"abstract":"Gold nanotetrapods (NTPs) possess sharp branched tips, high surface-to-volume ratios, and strong localized surface plasmon resonance in the near-infrared (NIR) region, making them candidates for biomedical applications. However, their practical use is limited by structural instability and inadequate biocompatibility in complex physiological environments. In this study, we developed an innovative in situ radical polymerization technique to encapsulate NTPs with a thin, cross-linked zwitterionic polymer shell, forming highly stable and biocompatible nanoparticles (NTP@XP). The polymer shell preserved the tetrapod structure and endowed NTPs with tunable surface properties through the polymerization of different monomers. Under NIR irradiation, NTP@XP exhibited enhanced photoacoustic imaging and a photothermal conversion performance in vitro. In vivo, the antifouling and biocompatible coating of NTP@XP allowed durable imaging and suppressed tumor regrowth in mice. This work establishes in situ polymerization as a robust strategy to stabilize NTPs, paving the way for various biomedical fields.","PeriodicalId":53,"journal":{"name":"Nano Letters","volume":"53 1","pages":""},"PeriodicalIF":10.8,"publicationDate":"2025-05-16","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144065777","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"材料科学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Measurement and Modeling of Electron and Hole Injection Dynamics in Quantum-Dot Light-Emitting Diodes: Quantifying Temperature-Dependent Charge Imbalance. 量子点发光二极管中电子和空穴注入动力学的测量和建模：量化温度相关电荷不平衡。

IF 10.8 1区材料科学

Nano Letters Pub Date : 2025-05-16 DOI: 10.1021/acs.nanolett.5c01227

Tianle Fan,Xitong Zhu,Shuai Chang,Xianchang Yan,Yizheng Jin,Shengye Jin,Boning Wu,Wenming Tian

引用次数: 0