Retinal Cases and Brief Reports最新文献

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RETINAL PHAKOMATOSIS AND VON HIPPEL-LINDAU PERIPHERAL CAPILLARY HEMANGIOBLASTOMA: PROPOSAL FOR STAGED SURGERY. 视网膜法孔症和 Von Hippel-Lindau 周围毛细血管血管母细胞瘤:分期手术建议。
Retinal Cases and Brief Reports Pub Date : 2025-03-01 DOI: 10.1097/ICB.0000000000001550
Carla E Gallenga, Lucia Zeppa, Ilaria De Pascale, Giulio Salerno, Paolo Tassinari, Paolo Perri, Lucio Zeppa
{"title":"RETINAL PHAKOMATOSIS AND VON HIPPEL-LINDAU PERIPHERAL CAPILLARY HEMANGIOBLASTOMA: PROPOSAL FOR STAGED SURGERY.","authors":"Carla E Gallenga, Lucia Zeppa, Ilaria De Pascale, Giulio Salerno, Paolo Tassinari, Paolo Perri, Lucio Zeppa","doi":"10.1097/ICB.0000000000001550","DOIUrl":"10.1097/ICB.0000000000001550","url":null,"abstract":"<p><strong>Purpose: </strong>Retinal capillary hemangioblastoma is present in about half of the carriers of the von Hippel-Lindau gene mutation and can lead to the evolution of blindness. Herewith is a proposal for surgical intraretinal feeder vessel ligature to induce ischemia of the phakoma and to resolve the exudative secondary retinal detachment, with satisfying results at the 6-month follow-up endpoint.</p><p><strong>Methods: </strong>The patient underwent a chandelier-assisted 23-gauge pars plana vitrectomy with valved trocars. A bimanual transretinal ligature of the feeder vessel of hemangioblastoma was performed, followed by localized endolaser to ablate the surrounding retina and capillaries, and a polydimethylsiloxane 1,000 final tamponade. After 3 months, exchange of polydimethylsiloxane/air/balanced salt solution, phacoemulsification, and in-the-bag intraocular lens implantation were performed.</p><p><strong>Results: </strong>At the sixth month, fundus fluorescein angiography showed a significant reduction of blood flow in the phakoma. The final best-corrected visual acuity was 6/6 (9 lines gain obtained compared with the baseline time).</p><p><strong>Conclusion: </strong>This surgical technique seems to be effective and promising for the treatment of von Hippel-Lindau retinal capillary hemangioblastomas and their related retinal complications.</p>","PeriodicalId":53580,"journal":{"name":"Retinal Cases and Brief Reports","volume":" ","pages":"205-209"},"PeriodicalIF":0.0,"publicationDate":"2025-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"139106812","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
POTASSIUM IODATE RETINOTOXICITY AFTER AN OVERDOSE OF ANTIRADIATION PILLS: A CASE OF APOCALYPTIC RETINOPATHY. 过量服用抗辐射药片后的碘酸钾视网膜毒性:一个世界末日视网膜病变的病例。
Retinal Cases and Brief Reports Pub Date : 2025-03-01 DOI: 10.1097/ICB.0000000000001548
Paul S Bernstein
{"title":"POTASSIUM IODATE RETINOTOXICITY AFTER AN OVERDOSE OF ANTIRADIATION PILLS: A CASE OF APOCALYPTIC RETINOPATHY.","authors":"Paul S Bernstein","doi":"10.1097/ICB.0000000000001548","DOIUrl":"10.1097/ICB.0000000000001548","url":null,"abstract":"<p><strong>Purpose: </strong>The aim of this study was to report a case of severe retinal toxicity after an attempted suicidal overdose of antiradiation pills containing a well-known retinal pigment epithelial toxin, potassium iodate.</p><p><strong>Methods: </strong>Clinical examination and multimodal imaging are provided from a clinic visit 11 years after the suicide attempt.</p><p><strong>Results: </strong>A 42-year-old patient had widespread retinal atrophy in both eyes with near-complete absence of the retinal pigment epithelium and severe retinal thinning. A few remaining areas of preserved photoreceptors provided her with 20/60 and 20/200 vision in her right and left eyes, respectively, with very constricted visual fields.</p><p><strong>Conclusion: </strong>Despite being first described over 100 years ago, few cases of iodate retinotoxicity have been reported in the published literature, and most are related to accidental or intentional ingestion of iodate salts used to iodize table salt. This unique case of iodate retinotoxicity secondary to antiradiation tablets highlights the risks of unregulated sale of these agents marketed in the United States as essential components of nuclear apocalypse \"go bags\" because they have a poor margin of safety and no specific warnings of the risk of permanent blindness with overdosage.</p>","PeriodicalId":53580,"journal":{"name":"Retinal Cases and Brief Reports","volume":"19 2","pages":"145-147"},"PeriodicalIF":0.0,"publicationDate":"2025-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11217146/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143505950","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
POOR VISUAL OUTCOMES IN SYPHILITIC UVEITIS ASSOCIATED WITH METHAMPHETAMINE USE: A CASE SERIES. 与吸食甲基苯丙胺有关的梅毒性葡萄膜炎视力不佳:病例系列。
Retinal Cases and Brief Reports Pub Date : 2025-03-01 DOI: 10.1097/ICB.0000000000001524
Jonathan Thomas, Harris Ahmed, Kathryn Halbritter, Moises Enghelberg
{"title":"POOR VISUAL OUTCOMES IN SYPHILITIC UVEITIS ASSOCIATED WITH METHAMPHETAMINE USE: A CASE SERIES.","authors":"Jonathan Thomas, Harris Ahmed, Kathryn Halbritter, Moises Enghelberg","doi":"10.1097/ICB.0000000000001524","DOIUrl":"10.1097/ICB.0000000000001524","url":null,"abstract":"<p><strong>Purpose: </strong>This study aimed to investigate the potential link between methamphetamine use and infectious syphilitic uveitis through a retrospective chart review of four patients with both conditions.</p><p><strong>Methods: </strong>A retrospective chart review was conducted on four patients with a history of methamphetamine use and presented with vision loss at an emergency department or clinic that was ultimately diagnosed as syphilitic uveitis.</p><p><strong>Results: </strong>The average age of the four patients was 41.5 ± 9.8 years, and each presented with symptoms of blurry vision after an average of 3 weeks. Clinical and serologic examinations revealed variable severity of syphilitic uveitis in each patient, and a confirmed history of methamphetamine use was found on a review of social history. Each patient had worsening visual outcomes after the initial presentation and diagnosis.</p><p><strong>Conclusion: </strong>Syphilitic uveitis is a challenging diagnosis because of its similarity with other ocular pathologies. This case series highlights the importance of maintaining a high level of suspicion for syphilis in patients with a history of methamphetamine use and uveitis to enable rapid treatment and prevent visual decline. The poor visual outcomes observed in these four patients underscore the significance of identifying and treating syphilitic uveitis promptly in this population and the barriers to treatment completion.</p>","PeriodicalId":53580,"journal":{"name":"Retinal Cases and Brief Reports","volume":" ","pages":"196-201"},"PeriodicalIF":0.0,"publicationDate":"2025-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"138804385","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
BILATERAL UVEITIS, RETINAL PERIPHLEBITIS, AND OPTIC NEURITIS ASSOCIATED WITH NON-PINEAL CENTRAL NERVOUS SYSTEM GERMINOMA. 双侧葡萄膜炎、视网膜静脉周围炎和视神经炎与非松果体中枢神经系统胚芽肿有关。
Retinal Cases and Brief Reports Pub Date : 2025-03-01 DOI: 10.1097/ICB.0000000000001523
Tianyu Liu, Apoorv P Chebolu, Caroline W Chung, Adam M Kruszewski, Nirali Bhatt, Alexander J Brucker
{"title":"BILATERAL UVEITIS, RETINAL PERIPHLEBITIS, AND OPTIC NEURITIS ASSOCIATED WITH NON-PINEAL CENTRAL NERVOUS SYSTEM GERMINOMA.","authors":"Tianyu Liu, Apoorv P Chebolu, Caroline W Chung, Adam M Kruszewski, Nirali Bhatt, Alexander J Brucker","doi":"10.1097/ICB.0000000000001523","DOIUrl":"10.1097/ICB.0000000000001523","url":null,"abstract":"<p><strong>Purpose: </strong>The aim of this study was to report a case of bilateral uveitis, retinal periphlebitis, and optic neuritis associated with a non-pineal central nervous system germinoma.</p><p><strong>Methods: </strong>This is a case report.</p><p><strong>Results: </strong>A 32-year-old man presented with episodes of acute painless visual disturbance in each eye and was found to have decreased VA, abnormal color vision, an afferent pupillary defect in the left eye, bilateral optic disc edema, perivenous sheathing, and candle-wax dripping exudates. Optical coherence tomography revealed bilateral intraretinal fluid and posterior vitreous hyperreflective opacities. Fluorescein angiography revealed bilateral optic disc leakage without active small vessel leakage. Magnetic resonance imaging of the brain and orbits revealed enhancing periventricular lesions and enhancement of the left optic nerve and bilateral perioptic nerve sheaths, posterior globes, and optic nerve heads. Brain biopsy was consistent with a central nervous system germinoma. His ocular signs and symptoms improved with chemotherapy for the germinoma.</p><p><strong>Conclusion: </strong>Central nervous system germinomas, including those located outside the pineal region, can be associated with optic neuritis, uveitis, and periphlebitis including characteristic candle-wax dripping exudates. Ocular signs and symptoms typically improve with treatment of the underlying germinoma.</p>","PeriodicalId":53580,"journal":{"name":"Retinal Cases and Brief Reports","volume":" ","pages":"182-186"},"PeriodicalIF":0.0,"publicationDate":"2025-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"138801359","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
CASE SERIES OF PROGRESSIVE RETINAL DETACHMENTS IN PERSISTENT FETAL VASCULATURE. 胎儿血管持续存在的进行性视网膜脱离病例系列。
Retinal Cases and Brief Reports Pub Date : 2025-03-01 DOI: 10.1097/ICB.0000000000001547
Nicole Somani, Jiwei Sheng, Prethy Rao, Emmanuel Chang
{"title":"CASE SERIES OF PROGRESSIVE RETINAL DETACHMENTS IN PERSISTENT FETAL VASCULATURE.","authors":"Nicole Somani, Jiwei Sheng, Prethy Rao, Emmanuel Chang","doi":"10.1097/ICB.0000000000001547","DOIUrl":"10.1097/ICB.0000000000001547","url":null,"abstract":"<p><strong>Purpose: </strong>Persistent fetal vasculature may be associated with tractional retinal detachment due to tractional contraction of the fibrovascular stalk. Persistent fetal vasculature is often believed to be congenital and nonprogressive. A rhegmatogenous component is far less common and is typically identified as a postoperative complication and has not been spontaneously reported. The authors present five cases illustrating potential progressive changes and complications that may arise in nonoperated persistent fetal vasculature.</p><p><strong>Methods: </strong>This was a retrospective case series of five patients who presented with progressive retinal detachments from persistent fetal vasculature.</p><p><strong>Results: </strong>Five unique cases of persistent fetal vasculature with significant progression from time of initial presentation, four of which included development of rhegmatogenous components.</p><p><strong>Conclusion: </strong>Patients with persistent fetal vasculature and a seemingly stable tractional detachment should undergo evaluation with a retinal specialist for risk stratification and management because rhegmatogenous detachments may occur due to ocular growth and stretch breaks, and tractional detachments can continue to progress over time.</p>","PeriodicalId":53580,"journal":{"name":"Retinal Cases and Brief Reports","volume":" ","pages":"267-272"},"PeriodicalIF":0.0,"publicationDate":"2025-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"139081040","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
OCCLUSIVE RETINAL VASCULITIS AS A PRESENTING FEATURE OF PRIMARY VITREORETINAL LYMPHOMA RELAPSE. 闭塞性视网膜血管炎是原发性玻璃体视网膜淋巴瘤复发的一种表现特征。
Retinal Cases and Brief Reports Pub Date : 2025-03-01 DOI: 10.1097/ICB.0000000000001551
Manasi Ketkar, Niroj Sahoo, Vishal Raval
{"title":"OCCLUSIVE RETINAL VASCULITIS AS A PRESENTING FEATURE OF PRIMARY VITREORETINAL LYMPHOMA RELAPSE.","authors":"Manasi Ketkar, Niroj Sahoo, Vishal Raval","doi":"10.1097/ICB.0000000000001551","DOIUrl":"10.1097/ICB.0000000000001551","url":null,"abstract":"<p><strong>Purpose: </strong>The aim of this study was to report a case of primary vitreoretinal lymphoma (PVRL) relapse presenting as occlusive retinal vasculitis with secondary neovascularization.</p><p><strong>Methods: </strong>This study was a retrospective case report.</p><p><strong>Results: </strong>A 40-year-old woman presented to the clinic with complaints of blurring of vision in the left eye for 4 months. Her best-corrected VA (BCVA) was 20/20 and 20/500 in the right and left eye, respectively. The vitreous cavities of both eyes showed vitreous opacities (2+). Both eyes fundus showed multifocal yellowish-white subretinal infiltration. A diagnostic vitreous and subretinal biopsy of the left eye revealed large lymphoid cells with CD-20 positivity, confirming the diagnosis of PVRL. The patient received 12 intravitreal methotrexate injections in both eyes over a course of 2 months, after which the lesions completely resolved. However, after 5 months, the left eye showed characteristic subretinal lesions along with perivascular exudates and retinal hemorrhages, diagnosed as PVRL relapse presenting as occlusive retinal vasculitis. Fluorescein angiography revealed retinal neovascularization, for which panretinal photocoagulation was performed along with repeated intravitreal methotrexate injections.</p><p><strong>Conclusion: </strong>Primary vitreoretinal lymphoma is a great masquerader, and although rare, PVRL relapse can present as occlusive retinal vasculitis with secondary neovascularization, thereby delaying diagnosis and subsequent treatment.</p>","PeriodicalId":53580,"journal":{"name":"Retinal Cases and Brief Reports","volume":" ","pages":"210-213"},"PeriodicalIF":0.0,"publicationDate":"2025-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"139081043","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
THE SPECTRUM OF RELENTLESS PLACOID AND ACUTE POSTERIOR MULTIFOCAL PLACOID PIGMENT EPITHELIOPATHY: A MULTIMODAL IMAGING ANALYSIS. 无鳞屑性和急性后多灶性鳞屑色素上皮病(APMPPE)的病变范围:多模态成像分析。
Retinal Cases and Brief Reports Pub Date : 2025-03-01 DOI: 10.1097/ICB.0000000000001555
Xavier Chan, Johnell Renz Amoroso, Quan V Hoang, Jesse J Jung
{"title":"THE SPECTRUM OF RELENTLESS PLACOID AND ACUTE POSTERIOR MULTIFOCAL PLACOID PIGMENT EPITHELIOPATHY: A MULTIMODAL IMAGING ANALYSIS.","authors":"Xavier Chan, Johnell Renz Amoroso, Quan V Hoang, Jesse J Jung","doi":"10.1097/ICB.0000000000001555","DOIUrl":"10.1097/ICB.0000000000001555","url":null,"abstract":"<p><strong>Purpose: </strong>The objective of this study was to showcase the spectrum between acute posterior multifocal placoid pigment epitheliopathy and relentless placoid utilizing ultra-widefield imaging findings of a case of acute posterior multifocal placoid pigment epitheliopathy progressing to relentless placoid chorioretinitis.</p><p><strong>Methods: </strong>A 23-year-old White woman presented with worsening vision in both eyes. Clinical examination and multimodal imaging modalities including fundus photographs, fundus autofluorescence, fluorescein angiography, indocyanine green angiography, and spectral domain optical coherence tomography and angiography were utilized to diagnose acute posterior multifocal placoid pigment epitheliopathy and clinically follow the patient.</p><p><strong>Results: </strong>Clinical examination of the patient initially revealed posterior lesions consistent with acute posterior multifocal placoid pigment epitheliopathy, but subsequent multimodal images including ultra-widefield fluorescein angiography and indocyanine green angiography revealed newer, more peripheral lesions more typical of relentless placoid chorioretinitis.</p><p><strong>Conclusion: </strong>When compared with standard multimodal imaging, ultra-widefield imaging is an effective tool to delineate nuances between acute posterior multifocal placoid pigment epitheliopathy and relentless placoid chorioretinitis through identification of peripheral lesions, which may be of clinical importance when determining management and therapeutics for patients.</p>","PeriodicalId":53580,"journal":{"name":"Retinal Cases and Brief Reports","volume":" ","pages":"148-151"},"PeriodicalIF":0.0,"publicationDate":"2025-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140029590","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
ACUTE ATROPHIC EVOLUTION OF DRUSENOID PIGMENT EPITHELIUM DETACHMENT AFTER PHOTOBIOMODULATION. 光生物调节术后类绒毛膜色素上皮脱落的急性萎缩性演变。
Retinal Cases and Brief Reports Pub Date : 2025-03-01 DOI: 10.1097/ICB.0000000000001529
Maurizio Battaglia Parodi, Alessio Antropoli, Alessandro Arrigo, Maria Vittoria Cicinelli, Lorenzo Bianco, Andrea Saladino, Enea Moretti, Francesco Bandello, Ahmad Mansour
{"title":"ACUTE ATROPHIC EVOLUTION OF DRUSENOID PIGMENT EPITHELIUM DETACHMENT AFTER PHOTOBIOMODULATION.","authors":"Maurizio Battaglia Parodi, Alessio Antropoli, Alessandro Arrigo, Maria Vittoria Cicinelli, Lorenzo Bianco, Andrea Saladino, Enea Moretti, Francesco Bandello, Ahmad Mansour","doi":"10.1097/ICB.0000000000001529","DOIUrl":"10.1097/ICB.0000000000001529","url":null,"abstract":"<p><strong>Purpose: </strong>The aim of this study was to report the acute onset of macular atrophy soon after photobiomodulation (PBM) administration in a patient with intermediate age-related macular degeneration.</p><p><strong>Methods: </strong>Optical coherence tomography was performed in the study eye before and after PBM.</p><p><strong>Results: </strong>A patient with drusenoid pigment epithelium detachment (D-PED) underwent PBM. A few weeks after PBM, the D-PED collapsed, resulting in complete retinal pigment epithelium and outer retinal atrophy with visual acuity worsening.</p><p><strong>Conclusion: </strong>Thinning of the outer retinal layers over a D-PED and posterior hypertransmission may represent bad prognostic factors for PBM, accelerating the lesion's natural history toward atrophic evolution.</p>","PeriodicalId":53580,"journal":{"name":"Retinal Cases and Brief Reports","volume":" ","pages":"225-227"},"PeriodicalIF":0.0,"publicationDate":"2025-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"138801144","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
INDOCYANINE GREEN ANGIOGRAPHY OF OPTIC DISK GRANULOMA IN OCULAR SARCOIDOSIS. 眼肉样瘤病视盘肉芽肿的吲哚菁绿血管造影。
Retinal Cases and Brief Reports Pub Date : 2025-03-01 DOI: 10.1097/ICB.0000000000001534
Matias Soifer, Nam V Nguyen, Boonkit Purt, Sunil Bellur, Shilpa Kodati
{"title":"INDOCYANINE GREEN ANGIOGRAPHY OF OPTIC DISK GRANULOMA IN OCULAR SARCOIDOSIS.","authors":"Matias Soifer, Nam V Nguyen, Boonkit Purt, Sunil Bellur, Shilpa Kodati","doi":"10.1097/ICB.0000000000001534","DOIUrl":"10.1097/ICB.0000000000001534","url":null,"abstract":"<p><strong>Purpose: </strong>The aim of this study was to report novel indocyanine green angiography findings of optic disk granulomas secondary to sarcoidosis.</p><p><strong>Methods: </strong>This was an observational case report.</p><p><strong>Results: </strong>A 36-year-old White man, who had previously been evaluated for birdshot chorioretinopathy and tested HLA-A29 negative, was referred for evaluation of choroidal lesions in both eyes. Fundus examination revealed ovoid choroidal lesions bilaterally in the posterior pole. Optical coherence tomography demonstrated bilateral focal choroidal elevations in the posterior pole and optic disks consistent with granulomas. Indocyanine green angiography revealed diffuse choroidal hypocyanescent spots with late-phase focal hypercyanescence of the optic disks in both eyes corresponding to the granulomas. After 3 months of prednisone and immunomodulatory treatment, the granulomas improved, and the optic disk hypercyanescence resolved.</p><p><strong>Conclusion: </strong>The authors describe a case of ocular sarcoidosis mimicking birdshot-like lesions, and indocyanine green angiography findings revealed late hypercyanescence, which resolved with treatment.</p>","PeriodicalId":53580,"journal":{"name":"Retinal Cases and Brief Reports","volume":" ","pages":"193-195"},"PeriodicalIF":0.0,"publicationDate":"2025-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11166885/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"138802195","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
A CASE REPORT OF TEMPORAL MACULAR THINNING ASSOCIATED WITH ALPORT SYNDROME. 颞部黄斑变薄合并alport综合征1例报告。
Retinal Cases and Brief Reports Pub Date : 2025-03-01 DOI: 10.1097/ICB.0000000000001593
Paul S Bernstein
{"title":"A CASE REPORT OF TEMPORAL MACULAR THINNING ASSOCIATED WITH ALPORT SYNDROME.","authors":"Paul S Bernstein","doi":"10.1097/ICB.0000000000001593","DOIUrl":"10.1097/ICB.0000000000001593","url":null,"abstract":"<p><strong>Purpose: </strong>The objective of this study was to report a case of severe temporal macular thinning in a patient with Alport syndrome. Bilateral temporal thinning is rarely associated with any other systemic conditions, so it is important that ophthalmologists be aware of the significance of this finding and refer for further internal medicine evaluation appropriately.</p><p><strong>Methods: </strong>Clinical examination and multimodal imaging are provided from a clinic visit one month after inpatient treatment for a hypertensive crisis associated with renal failure.</p><p><strong>Results: </strong>The 19-year-old patient had resolving hypertensive retinopathy. High-resolution optical coherence tomography confirmed that he had temporal thinning indices consistent with his underlying clinical diagnosis of Alport syndrome.</p><p><strong>Conclusion: </strong>This case report emphasizes the important role of optical coherence tomography as a commonly available noninvasive retinal imaging modality that can readily demonstrate the temporal macular thinning that is characteristic of Alport syndrome and just a few other conditions. Optical coherence tomography can be an attractive alternative to the much more invasive renal biopsy testing for Alport syndrome when genetic testing is ambiguous or when renal biopsy is considered too risky for the patient.</p>","PeriodicalId":53580,"journal":{"name":"Retinal Cases and Brief Reports","volume":"19 2","pages":"157-159"},"PeriodicalIF":0.0,"publicationDate":"2025-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143505948","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
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