Retinal Cases and Brief Reports最新文献_第4页

Management of Perifoveal Exudative Vascular Anomalous Complex. 眼底渗出性血管异常复合体的处理方法

Retinal Cases and Brief Reports Pub Date : 2024-08-05 DOI: 10.1097/ICB.0000000000001649

Maria Cristina Savastano, Claudia Fossataro, Gianni Gravina, Francesca Coccimiglio, Clara Rizzo, Stanislao Rizzo

{"title":"Management of Perifoveal Exudative Vascular Anomalous Complex.","authors":"Maria Cristina Savastano, Claudia Fossataro, Gianni Gravina, Francesca Coccimiglio, Clara Rizzo, Stanislao Rizzo","doi":"10.1097/ICB.0000000000001649","DOIUrl":"https://doi.org/10.1097/ICB.0000000000001649","url":null,"abstract":"Purpose: To report a case of a patient with perifoveal exudative vascular anomalous complex (PEVAC) and to analyze morphological and vascular changes by OCT and OCTA before and after treatment.Materials and methods: In this case we reported a case which received multiple treatment for unresponsive effect to Repeated Aflibercept intravitreal injections, subthreshold micropulse laser therapy (SMPL) duty cycle 5%. At last the focal fully dose yellow laser was performed.Results: A 57-year-old male patient presented with best corrected visual acuity (BCVA) of 20/50 in his right eye (RE) The fundoscopic evaluation, structural optical coherence tomography (OCT) and OCT angiography (OCTA) deposed for a diagnosis of PEVAC. The patient underwent three Aflibercept intravitreal injections in the RE. Since no changes were detected, we opted for multiple sessions of yellow subthreshold micropulse laser therapy (SMPL) duty cycle 5%, however no signs of regression were registered. Only after a fully dose yellow laser, signs of edema regression were observed. Stuctural OCT B-scan showed complete restitutio of retinal profile, in absence of any intraretinal or subretinal fluid and PEVAC lesion, while the OCTA showed a slight flow deficit at the previous lesion site.Conclusions: and Importance: The PEVAC treatment is still unknown. In our experience, we reported a case of multiple treatments for unresponsive effect to: Aflibercept intravitreal injections, subthreshold micropulse laser therapy (SMPL) duty cycle 5%. At list the focal fully dose yellow laser was the only effective in our patient. We proposed our management to share the heterogeneous response at PEVAC entity.","PeriodicalId":53580,"journal":{"name":"Retinal Cases and Brief Reports","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2024-08-05","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141898906","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Treatment of Nocardia Chorioretinitis Related Choroidal Neovascularization with Aflibercept: A Case of Unveiled Immunocompromise with anti-GM-CSF Antibodies. 用 Aflibercept 治疗诺卡氏脉络膜视网膜炎相关脉络膜新生血管：抗GM-CSF抗体揭示免疫功能低下的病例。

Retinal Cases and Brief Reports Pub Date : 2024-08-02 DOI: 10.1097/ICB.0000000000001646

Edward Korot, Katherine E Jaje, Neena Singhal, Maria C Miglio

{"title":"Treatment of Nocardia Chorioretinitis Related Choroidal Neovascularization with Aflibercept: A Case of Unveiled Immunocompromise with anti-GM-CSF Antibodies.","authors":"Edward Korot, Katherine E Jaje, Neena Singhal, Maria C Miglio","doi":"10.1097/ICB.0000000000001646","DOIUrl":"https://doi.org/10.1097/ICB.0000000000001646","url":null,"abstract":"Purpose: The purpose of this study was to describe a case of Nocardia chorioretinitis-related choroidal neovascularization (CNV) in a patient with anti-GM-CSF antibodies with resolution of choroidal neovascularization and visual recovery following a series of intravitreal anti-vascular endothelial growth factor.Methods: This study is a case report.Results: In our case, a 50-year-old female, thought to be immunocompetent, presented with metamorphopsia and decreased visual acuity in the left eye in the setting of disseminated Nocardiosis. She had evidence of a subfoveal Nocardia lesion with subretinal fluid and CNV. Following a series of off-label injections with aflibercept, the patient had improvement in lesion size, exudation, and visual acuity. Extensive workup yielded underlying immunocompromise due to presence of anti-GM-CSF antibodies, likely predisposing her to disseminated Nocardiosis.Conclusion: The use of aflibercept in Nocardia chorioretinitis led to resolution of neovascular activity with visual recovery in a patient with disseminated Nocardiosis.","PeriodicalId":53580,"journal":{"name":"Retinal Cases and Brief Reports","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2024-08-02","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141879775","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Secondary Multiple Evanescent White Dot Syndrome Following Blunt Trauma. 钝器创伤后的继发性多发白点综合征

Retinal Cases and Brief Reports Pub Date : 2024-08-02 DOI: 10.1097/ICB.0000000000001648

Samantha R Goldburg, Jennifer Adeghate, Gaetano R Barile, Talia R Kaden

{"title":"Secondary Multiple Evanescent White Dot Syndrome Following Blunt Trauma.","authors":"Samantha R Goldburg, Jennifer Adeghate, Gaetano R Barile, Talia R Kaden","doi":"10.1097/ICB.0000000000001648","DOIUrl":"https://doi.org/10.1097/ICB.0000000000001648","url":null,"abstract":"Purpose: To report a case of secondary unilateral MEWDS following blunt trauma to the eye.Methods: Observational case report of one patient.Results: A 25-year-old male initially presented after being hit in the left eye with a football, with visual acuity of 20/50, traumatic iritis, commotio retinae, vitreous hemorrhage, and a large pigment epithelial detachment in the superior macula. He was lost to follow-up for two years before presenting with a sudden decrease in vision. On exam, best corrected VA (BCVA) was counting fingers and clinical exam demonstrated fibrosis in the superior macula, small white lesions around the optic disc and throughout the posterior pole, and ellipsoid zone disruption on OCT. Given the clinical appearance, a diagnosis of Multiple Evanescent White Dot Syndrome was made and the decision was made to observe. Two months later, without treatment, BCVA improved to 20/20, and there was resolution of the white lesions in the posterior pole as well as improved continuity of the ellipsoid zone on OCT.Discussion: We describe a case of Multiple Evanescent White Dot Syndrome two years after blunt trauma to the eye; a far longer latency than previously reported cases of MEWDS secondary to blunt trauma.","PeriodicalId":53580,"journal":{"name":"Retinal Cases and Brief Reports","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2024-08-02","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141879774","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Improvement of Tamoxifen Induced Foveal Cavitation with Topical Dorzolamide Therapy. 使用局部多佐胺疗法改善他莫昔芬诱发的眼窝凹陷。

Retinal Cases and Brief Reports Pub Date : 2024-07-29 DOI: 10.1097/ICB.0000000000001645

Khalil Ghasemi Falavarjani, David Sarraf

引用次数: 0

Autologous Tenon's capsule graft for the management of subfoveal detachment due to myopic paracentral macular break. 自体腱膜囊移植治疗近视旁中心黄斑破裂引起的眼底脱离。

Retinal Cases and Brief Reports Pub Date : 2024-07-25 DOI: 10.1097/ICB.0000000000001635

Jorge Fernández-Engroba, Ester Roquet, Pedro Tañá-Sanz, Bernat Nadal, Jeroni Nadal

引用次数: 0

A case of AZOOR under immunomodulatory treatment. 一个接受免疫调节治疗的 AZOOR 病例。

Retinal Cases and Brief Reports Pub Date : 2024-07-23 DOI: 10.1097/ICB.0000000000001643

David A Merle, Lasse Wolfram, Emil Nasyrov, Milda Reith, Martin Kowalski, Melanie Kempf, Lisa Strudel, Deshka Doycheva, Christoph Deuter, Katarina Stingl, Laura Kühlewein

{"title":"A case of AZOOR under immunomodulatory treatment.","authors":"David A Merle, Lasse Wolfram, Emil Nasyrov, Milda Reith, Martin Kowalski, Melanie Kempf, Lisa Strudel, Deshka Doycheva, Christoph Deuter, Katarina Stingl, Laura Kühlewein","doi":"10.1097/ICB.0000000000001643","DOIUrl":"10.1097/ICB.0000000000001643","url":null,"abstract":"Purpose: To describe the clinical course and treatment response of a case of Acute Zonal Occult Outer Retinopathy (AZOOR).Methods: This is an observational case report. The examinations included ophthalmic examination, longitudinal multimodal imaging, visual field testing, electrophysiological recordings, serologic analyses and whole genome sequencing.Results: In this report, the authors present the case of an otherwise healthy 33-year-old female with bilateral AZOOR manifestation. Other possible causes of the observed retinal lesions were ruled out by extensive diagnostic work-up. Treatment with oral prednisolone therapy led to temporal disease control but progression was observed after prednisolone discontinuation. A tapered oral prednisolone therapy in combination with adalimumab initiation prevented further progression for at least 21 months.Conclusion: Diagnosis of AZOOR is frequently complicated by the unspecific symptoms of the disease and significant number of differential diagnoses. Complete diagnostic work-up is important to rule out other etiologies. Due to the lack of randomized controlled trials, therapeutic decisions obligatorily rely on empiric treatment decisions in combination with frequent follow-up examinations.","PeriodicalId":53580,"journal":{"name":"Retinal Cases and Brief Reports","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2024-07-23","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141767986","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Severe Circulatory Disturbance in Optic Disc, Retina, and Choroid Following Sub-Tenon Triamcinolone Acetonide Injection for Posterior Scleritis. 瞳孔下注射曲安奈德（Triamcinolone Acetonide）治疗后巩膜炎后，视盘、视网膜和脉络膜出现严重循环障碍。

Retinal Cases and Brief Reports Pub Date : 2024-07-23 DOI: 10.1097/ICB.0000000000001642

Masahiro Akada, Yuki Muraoka, Satoshi Morooka, Kenji Ishihara, Masayuki Hata, Akitaka Tsujikawa

{"title":"Severe Circulatory Disturbance in Optic Disc, Retina, and Choroid Following Sub-Tenon Triamcinolone Acetonide Injection for Posterior Scleritis.","authors":"Masahiro Akada, Yuki Muraoka, Satoshi Morooka, Kenji Ishihara, Masayuki Hata, Akitaka Tsujikawa","doi":"10.1097/ICB.0000000000001642","DOIUrl":"10.1097/ICB.0000000000001642","url":null,"abstract":"Purpose: To report a rare case of optic disc and chorioretinal vascular occlusions in the right eye following sub-Tenon injection of triamcinolone acetonide (STTA) in an older male patient with scleritis and to discuss the associated risk factors and potential alternative therapies.Methods: The medical history and clinical examination, including fundoscopy, fluorescein angiography (FA), and indocyanine green angiography (ICGA), were conducted to diagnose and evaluate the extent of vascular occlusion after STTA. An extensive literature review was undertaken to ascertain the associated risks and consider other treatment options for scleritis.Results: Severe circulatory disturbances in the optic disc and chorioretinal regions of the right eye developed after STTA for exacerbated scleritis, as confirmed by FA and ICGA, resulting in a significant decrease in visual acuity. A complex medical history encompassing ophthalmic and systemic health issues may have contributed to this negative outcome. A literature review pointed out the potential complications of STTA and highlighted alternative approaches to scleritis management.Conclusions: Cautious application of STTA in treating scleritis is crucial, especially in patients with pre-existing vascular or ocular conditions. Thus, a multidisciplinary approach and a careful assessment of various treatment options are vital to minimize the risk of severe complications and improve patient outcomes.","PeriodicalId":53580,"journal":{"name":"Retinal Cases and Brief Reports","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2024-07-23","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141767988","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Ocular Sarcoidosis Masquerading as Acute Retinal Necrosis: Two Case Reports. 伪装成急性视网膜坏死的眼肉样瘤病：两个病例报告

Retinal Cases and Brief Reports Pub Date : 2024-07-19 DOI: 10.1097/ICB.0000000000001639

Hsin-Ming Liu, Yung-Jen Lai, Fang-Yi Chiu, Wei-Chun Chan

{"title":"Ocular Sarcoidosis Masquerading as Acute Retinal Necrosis: Two Case Reports.","authors":"Hsin-Ming Liu, Yung-Jen Lai, Fang-Yi Chiu, Wei-Chun Chan","doi":"10.1097/ICB.0000000000001639","DOIUrl":"https://doi.org/10.1097/ICB.0000000000001639","url":null,"abstract":"Purpose: To report two cases of ocular sarcoidosis (OS) initially presenting as unilateral acute retinitis, which mimicked acute retinal necrosis.Methods: Retrospective descriptive case reports.Results: Two middle-aged healthy Asian women experienced progressive vision loss in their left eyes over a one-month period. Anterior uveitis, vitritis, and diffuse peripheral retinal infiltration were observed. Comprehensive diagnostic evaluations were conducted, including blood work-up, viral polymerase chain reaction of anterior chamber paracentesis samples, and chest X-ray, all yielding negative results. Despite prompt initiation of antiviral therapy, retinal infiltrations remained unchanged within the first 10 days. Chest CT imaging revealed multiple lymphadenopathies consistent with sarcoidosis. Case 1 was presumed OS, and case 2 was definite OS based on lung and lymph node biopsy results in accordance with the 2017 revised international workshop on OS (IWOS) criteria. In both cases, the retinal lesions gradually resolved after several weeks of systemic corticosteroids, and the best corrected vision of the affected eye improved to 20/25 at the 12 and 6-month follow-ups, respectively.Conclusion: Acute unilateral retinal infiltration in the peripheral region, exhibiting rapid progression resembling acute retinal necrosis, can be a rare manifestation of OS. Chest CT imaging can provide valuable assistance in the diagnostic process, especially when systemic examinations yield no significant findings.","PeriodicalId":53580,"journal":{"name":"Retinal Cases and Brief Reports","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2024-07-19","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141728293","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

PUNCTATE INNER CHOROIDOPATHY FOLLOWING PARS PLANA VITRECTOMY FOR HIGH MYOPIC FULL THICKNESS MACULAR HOLE. 高度近视全厚黄斑孔玻璃体旁切除术后的点状内脉络膜病变。

Retinal Cases and Brief Reports Pub Date : 2024-07-19 DOI: 10.1097/ICB.0000000000001641

Alessandro Feo, Enrico Giacomotti, Francesco Santoru, Lorenzo Crepaldi, Daniele Criscuolo, Davide Allegrini, Mario R Romano

{"title":"PUNCTATE INNER CHOROIDOPATHY FOLLOWING PARS PLANA VITRECTOMY FOR HIGH MYOPIC FULL THICKNESS MACULAR HOLE.","authors":"Alessandro Feo, Enrico Giacomotti, Francesco Santoru, Lorenzo Crepaldi, Daniele Criscuolo, Davide Allegrini, Mario R Romano","doi":"10.1097/ICB.0000000000001641","DOIUrl":"https://doi.org/10.1097/ICB.0000000000001641","url":null,"abstract":"Purpose: To describe a case of punctate inner choroidopathy (PIC) and secondary or epiphenomenon multiple evanescent white dot syndrome (EpiMEWDS) following surgery for high myopic full-thickness macular hole (FTMH).Methods: Case report.Results: A 57-year-old high myopic female was diagnosed with cataract and FTMH in the left eye. Her initial best-corrected visual acuity (BCVA) was 20/20 in her right eye and 20/80 in the left eye. She underwent routine combined phacoemulsification and 25-gauge pars plana vitrectomy (PPV) with the inverted internal limiting membrane (ILM) technique and twice-repeated epiretinal membrane (ERM) and ILM staining in the left eye. Two weeks postoperatively, the patient reported significant visual decline and photopsia in her left eye. BCVA decreased to counting fingers. Anterior segment examination was unremarkable. Ophthalmoscopic examination showed multiple whitish-yellow lesions in the macular region compatible with PIC lesions in the left eye. Optical coherence tomography (OCT), blue-light fundus autofluorescence (BAF), fluorescein angiography, and indocyanine green angiography were performed and confirmed the diagnosis. The patient underwent oral steroid therapy for PIC treatment. One week after treatment initiation, BAF showed the occurrence of EpiMEWDS. After one month, all lesions resolved and BCVA improved to 20/100.Conclusions: We report a rare case of PIC and EpiMEWDS development following surgery for FTMH. We hypothesize that several causes, including individual susceptibility (high myopia and female gender), post-surgical inflammation, and/or dye toxicity due to repeated staining could have amplified this inflammatory chorioretinal response. Larger studies are needed to better understand the potential triggers of PIC development after surgery.","PeriodicalId":53580,"journal":{"name":"Retinal Cases and Brief Reports","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2024-07-19","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141728294","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Bilateral Central serous chorioretinopathy in a case of surgically treated Optic Disc Pit maculopathy. 一例经手术治疗的视盘凹陷性黄斑病变患者的双侧中央浆液性脉络膜视网膜病变。

Retinal Cases and Brief Reports Pub Date : 2024-07-19 DOI: 10.1097/ICB.0000000000001630

Urvashi Kala, Ahana Sen, Bristi Majumdar, Pragya Shambhawi, Aarzoo Juneja, N Sai Divya, Ruchira Chowdhury, Kumar Saurabh, Rupak Roy

{"title":"Bilateral Central serous chorioretinopathy in a case of surgically treated Optic Disc Pit maculopathy.","authors":"Urvashi Kala, Ahana Sen, Bristi Majumdar, Pragya Shambhawi, Aarzoo Juneja, N Sai Divya, Ruchira Chowdhury, Kumar Saurabh, Rupak Roy","doi":"10.1097/ICB.0000000000001630","DOIUrl":"https://doi.org/10.1097/ICB.0000000000001630","url":null,"abstract":"Purpose: To report occurrence of central serous chorioretinopathy(CSCR) which mimicked recurrence of ODP maculopathy in a young adult in whom surgery for the same had been done.Methods: Clinical fundus examination and multimodal imaging which included optical coherence tomography(OCT) and fundus autofluorescence(FFA) was done.Results: Patient had undergone surgery for ODP maculopathy. At 1 year follow up, there was recurrence of subretinal fluid at the macula. Fundus fluorescein angiography was done and the presence of ink blot pattern leakage clinched the diagnosis of CSCR, ruling out ODP maculopathy.Conclusion: CSCR is a great masquerade and correct diagnosis is very important to prevent permanent visual impairment. Subretinal fluid(SRF) associated with ODP must be examined carefully to rule out other pathologies like CSCR. Serous macular detachment after surgery for ODP maculopathy has been done, does not necessarily mean recurrence of the maculopathy. Other pathologies like CSCR should be ruled out. This case highlights the importance of multimodal imaging along with clinical signs in correct diagnosis and treatment of conditions with overlapping features like CSCR and ODP maculopathy.","PeriodicalId":53580,"journal":{"name":"Retinal Cases and Brief Reports","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2024-07-19","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141728287","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0