Maurizio Battaglia Parodi, Alessio Antropoli, Alessandro Arrigo, Maria Vittoria Cicinelli, Lorenzo Bianco, Andrea Saladino, Enea Moretti, Francesco Bandello, Ahmad Mansour
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Abstract
Purpose: The aim of this study was to report the acute onset of macular atrophy soon after photobiomodulation (PBM) administration in a patient with intermediate age-related macular degeneration.
Methods: Optical coherence tomography was performed in the study eye before and after PBM.
Results: A patient with drusenoid pigment epithelium detachment (D-PED) underwent PBM. A few weeks after PBM, the D-PED collapsed, resulting in complete retinal pigment epithelium and outer retinal atrophy with visual acuity worsening.
Conclusion: Thinning of the outer retinal layers over a D-PED and posterior hypertransmission may represent bad prognostic factors for PBM, accelerating the lesion's natural history toward atrophic evolution.
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