Retinal Cases and Brief Reports最新文献

PATCHY ATROPHIC PERIVASCULAR LESIONS IN VITREORETINAL LYMPHOMAS: A CASES SERIES. 玻璃体视网膜淋巴瘤的斑片状萎缩性血管周围病变：1例系列。

Retinal Cases and Brief Reports Pub Date : 2025-04-07 DOI: 10.1097/ICB.0000000000001761

Maxime Desira, Thibault Ruiz, Magali Sampo, Thierry David, Pierre Gascon

{"title":"PATCHY ATROPHIC PERIVASCULAR LESIONS IN VITREORETINAL LYMPHOMAS: A CASES SERIES.","authors":"Maxime Desira, Thibault Ruiz, Magali Sampo, Thierry David, Pierre Gascon","doi":"10.1097/ICB.0000000000001761","DOIUrl":"https://doi.org/10.1097/ICB.0000000000001761","url":null,"abstract":"Purpose: Vitreoretinal lymphoma (VRL) is a rare but aggressive intraocular malignancy, often presenting diagnostic challenges due to its masquerade syndrome characteristics. This study reports on two atypical cases of VRL, highlighting the presence of patchy atrophic perivascular retinal lesions, a feature not commonly emphasized in the literature.Methods: Cases series.Results: The first case involves an 83-year-old woman with primary VRL in her right eye, where progressive atrophic retinal lesions were noted despite systemic chemotherapy. The second case describes a 77-year-old woman with secondary VRL, previously in remission from cerebral lymphoma, who also developed perivascular atrophic lesions in her right eye. These lesions were observed to increase in both number and size over time, even in the absence of active vitreoretinal infiltration or systemic disease relapse.Conclusion: These cases suggest that the patchy atrophic perivascular lesions may be indicative of VRL. The atrophic progression, despite local disease control, underscores the importance of recognizing such patterns as part of the broader spectrum of VRL manifestations. It contributes to the ongoing discussion of minimal residual disease in VRL management.","PeriodicalId":53580,"journal":{"name":"Retinal Cases and Brief Reports","volume":" ","pages":""},"PeriodicalIF":0.0,"publicationDate":"2025-04-07","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143813060","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Retinal dystrophy as an unusual manifestation of trichothiodystrophy. 视网膜营养不良是毛硫营养不良的一种不寻常的表现。

Retinal Cases and Brief Reports Pub Date : 2025-04-02 DOI: 10.1097/ICB.0000000000001756

Fernanda Galante Dourado, Daniel Queiroz Omote, Paula Dandara Correia de Pinho, Sergio Luis Gianotti Pimentel

引用次数: 0

A Novel Case Study of Unilateral Serous Retinal Detachment in a Glaucoma Patient with Nephrotic Syndrome. 肾病综合征青光眼患者单侧浆液性视网膜脱离的新病例研究。

Retinal Cases and Brief Reports Pub Date : 2025-04-02 DOI: 10.1097/ICB.0000000000001755

Robert D Nguyen, Martin Dionson, Emmanuel Agu, John A Gonzales

{"title":"A Novel Case Study of Unilateral Serous Retinal Detachment in a Glaucoma Patient with Nephrotic Syndrome.","authors":"Robert D Nguyen, Martin Dionson, Emmanuel Agu, John A Gonzales","doi":"10.1097/ICB.0000000000001755","DOIUrl":"https://doi.org/10.1097/ICB.0000000000001755","url":null,"abstract":"Purpose: To present a case of a unilateral serous retinal detachment in a patient with nephrotic syndrome following Ahmed valve implantation.Methods: Retrospective descriptive case report.Results: A 63-year-old male with a history of Ahmed valve implantation, diabetes, and hypertension presented with progressive corneal edema and decreased vison who developed a serous retinal detachment in the right eye. There was no view of the fundus due to the massive retinal detachment. B-scan ultrasound revealed a serous retinal detachment with mild choroidal thickening. Along with the development of anasarca, laboratory testing revealed significant proteinuria and hypoalbuminemia, consistent with nephrotic syndrome. Fluid restriction and treatment with diuretics and anti-hypertensives resulted in rapid resolution of the serous retinal detachment.Conclusions: Though nephrotic syndrome can cause central serous retinal detachment, the presentation is almost always bilateral. A unilateral serous retinal detachment presentation can occur in patients with risk factors such as a history of Ahmed valve implantation and conditions that alter intravascular fluid hydrostatic and oncotic pressures. Prompt recognition of nephrotic syndrome in patients with kidney disease who develop serous retinal detachment is critical. Early treatment with diuretic therapy can significantly resolve ocular complications and potentially improve patient outcomes.","PeriodicalId":53580,"journal":{"name":"Retinal Cases and Brief Reports","volume":" ","pages":""},"PeriodicalIF":0.0,"publicationDate":"2025-04-02","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143784500","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

First report of Raoultella ornithinolytica endophthalmitis. 溶鸟膜拉乌尔氏菌眼内炎首例报道。

Retinal Cases and Brief Reports Pub Date : 2025-04-02 DOI: 10.1097/ICB.0000000000001758

Mannat Giran, Himansu Sekhar Behera, Ridham Nanda, Srikanta Kumar Padhy

{"title":"First report of Raoultella ornithinolytica endophthalmitis.","authors":"Mannat Giran, Himansu Sekhar Behera, Ridham Nanda, Srikanta Kumar Padhy","doi":"10.1097/ICB.0000000000001758","DOIUrl":"https://doi.org/10.1097/ICB.0000000000001758","url":null,"abstract":"Purpose: This report aims to document a rare case of endophthalmitis caused by Raoultella ornithinolytica, emphasizing its clinical presentation, diagnostic considerations, and the challenges encountered in managing this emerging ocular pathogen.Methods: Clinical examination, imaging studies, surgical interventions, microbiological analysis, and antibiotic susceptibility testing were employed to diagnose and manage the case.Results: A 50-year-old male presented with severe pain and vision loss following a projectile injury to the right eye. Initial examination revealed a self-sealed full-thickness corneal laceration, posterior subluxation of the lens, and the presence of a hyperdense intraocular foreign body (IOFB). The patient underwent vitreoretina interventions, including anterior chamber wash, vitreous biopsy, pars plana lensectomy, and vitrectomy with silicone oil injection, during which the metallic IOFB was removed. Raoultella ornithinolytica was identified through vitreous fluid culture, presenting a unique challenge due to limited literature on its ocular manifestations. Despite prompt surgical interventions and tailored antibiotic therapy, the infection was effectively managed, but the retina remained detached under oil at 2 months postoperatively.Conclusion: This case highlights the importance of recognizing and managing uncommon pathogens such as Raoultella ornithinolytica in ocular infections, underscoring the need for vigilant diagnostic and therapeutic approaches tailored to antimicrobial susceptibility profiles.","PeriodicalId":53580,"journal":{"name":"Retinal Cases and Brief Reports","volume":" ","pages":""},"PeriodicalIF":0.0,"publicationDate":"2025-04-02","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143784503","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Occlusive Retinal Vasculitis After Aflibercept 8mg Injection for Wet Macular Degeneration. 注射阿非利赛8mg治疗湿性黄斑变性后视网膜血管闭塞性炎。

Retinal Cases and Brief Reports Pub Date : 2025-04-02 DOI: 10.1097/ICB.0000000000001757

Robert A Sisk

{"title":"Occlusive Retinal Vasculitis After Aflibercept 8mg Injection for Wet Macular Degeneration.","authors":"Robert A Sisk","doi":"10.1097/ICB.0000000000001757","DOIUrl":"https://doi.org/10.1097/ICB.0000000000001757","url":null,"abstract":"Purpose: To describe a case of occlusive retinal vasculitis (ORV) following intravitreal aflibercept 8mg injection for wet macular degeneration.Methods: Retrospective, interventional case report.Results: A 72-year-old female presented with classic ORV 11 days after intravitreal aflibercept 8mg injection in her left eye for wet macular degeneration. Visual acuity (VA) declined from 20/30 to 20/400. Laboratory investigations including Gram stain and cultures of vitreous aspirate, studies for infectious and non-infectious uveitis and hypercoagulable state were all negative. Oral prednisone, sub-Tenon's triamcinolone acetonide (STTA), intravitreal dexamethasone and antibiotic injections, and topical steroids resulted in visual and anatomic improvement. ORV recurred when prednisone was tapered to 10mg/day and was controlled with additional STTA, oral solumedrol, and a 0.18mg fluocinolone acetonide implant. Subsequently exudation from wet macular degeneration recurred and responded to intravitreal faricimab with recovery to 20/30.Conclusions: ORV is a rare complication of some intravitreal anti-VEGF medications and infectious causes of endophthalmitis. It can be managed with aggressive steroid treatment for an excellent visual outcome in some cases, although the disease may be chronic or recurrent.","PeriodicalId":53580,"journal":{"name":"Retinal Cases and Brief Reports","volume":" ","pages":""},"PeriodicalIF":0.0,"publicationDate":"2025-04-02","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143784506","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

DELAYED ONSET OF SPONTANEOUS LARGE FULL THICKNESS MACULAR HOLE CLOSURE. 自发性大全层黄斑孔闭合延迟发生。

Retinal Cases and Brief Reports Pub Date : 2025-03-31 DOI: 10.1097/ICB.0000000000001750

Muntadher Al Karam, Rike Michels, Stephan Michels

引用次数: 0

Occult invasive fungal sinusitis in a patient with acute Vogt-Koyanagi-Harada Disease (VKHD). 急性Vogt-Koyanagi-Harada病隐匿性侵袭性鼻窦炎1例。

Retinal Cases and Brief Reports Pub Date : 2025-03-31 DOI: 10.1097/ICB.0000000000001754

Emily C Davis, Akshay S Thomas

{"title":"Occult invasive fungal sinusitis in a patient with acute Vogt-Koyanagi-Harada Disease (VKHD).","authors":"Emily C Davis, Akshay S Thomas","doi":"10.1097/ICB.0000000000001754","DOIUrl":"https://doi.org/10.1097/ICB.0000000000001754","url":null,"abstract":"Purpose: We present a case of the development of invasive fungal sinusitis in a patient with acute Vogt-Koyanagi-Harada Disease (VKHD).Methods: Observational case report.Results: A 39-year-old African American female presented with acute vision loss in both eyes and reported pain around her left eye. Examination revealed a bilateral posterior uveitis with significant macular edema and subretinal fluid in both eyes. Systemic and ocular findings were consistent with complete VKHD and the patient was put on oral glucocorticoids. At follow-up 2 weeks later, blood sugars were found to be severely elevated, and the patient was hospitalized. During hospitalization, the patient was taken off steroids. At follow-up, the uveitis appeared quiescent, but vision was still poor in the left eye. The patient reported a continued sense of pressure and now numbness around the left eye. An MRI revealed occult invasive fungal sinusitis and the patient was hospitalized for treatment. The patient recovered after surgery for debridement of the sinuses and several weeks of treatment with amphotericin B. At the most recent follow up, 18 months following the initial visit, the patient's visual acuity was 20/20 OD and 20/50 with eccentric viewing OS.Conclusion: Many forms of uveitis such as acute VKHD require use of oral glucocorticoids. However, proper use of glucocorticoids involves patient counseling on potential side-effects and the prescribing physician to identify potential life-threatening complications. In this case, failure to identify either the severely elevated blood sugars or occult fungal sinusitis could have resulted in significant patient morbidity or even mortality.","PeriodicalId":53580,"journal":{"name":"Retinal Cases and Brief Reports","volume":" ","pages":""},"PeriodicalIF":0.0,"publicationDate":"2025-03-31","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143774878","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Polarization-sensitive optical coherence tomography features of the repair tissue following retinal pigment epithelium tear and functional correlation with visual outcomes. 视网膜色素上皮撕裂后修复组织的偏振敏感光学相干断层扫描特征及其与视力结果的功能相关性。

Retinal Cases and Brief Reports Pub Date : 2025-03-31 DOI: 10.1097/ICB.0000000000001752

Keiko Azuma, Daisuke Santo, Satoshi Sugiyama, Nobuyori Aoki, Shuichiro Aoki, Kohdai Kitamoto, Ryo Terao, Tatsuya Inoue, Ryo Obata

{"title":"Polarization-sensitive optical coherence tomography features of the repair tissue following retinal pigment epithelium tear and functional correlation with visual outcomes.","authors":"Keiko Azuma, Daisuke Santo, Satoshi Sugiyama, Nobuyori Aoki, Shuichiro Aoki, Kohdai Kitamoto, Ryo Terao, Tatsuya Inoue, Ryo Obata","doi":"10.1097/ICB.0000000000001752","DOIUrl":"https://doi.org/10.1097/ICB.0000000000001752","url":null,"abstract":"Purpose: To investigate changes in melanin distribution and retinal sensitivity following a retinal pigment epithelium (RPE) tear in neovascular age-related macular degeneration (nAMD).Methods: Five cases of nAMD with RPE tears involving the fovea within 1 month of onset were examined. Using polarization-sensitive optical coherence tomography, entropy-a quantitative indicator of melanin distribution-was measured at baseline and 6 months at the level of Bruch's membrane. Retinal sensitivity was assessed with a microperimeter, and entropy was averaged across 25 grids within a 6-degree radius. The relationship between changes in entropy and retinal sensitivity was analyzed.Results: Entropy significantly increased in the tear area (from 0.19 to 0.22, p=0.026), whereas it decreased in the non-tear area. Retinal sensitivity also significantly increased in the tear area (from 12.7 to 16.3 dB, p=0.002). Although entropy and retinal sensitivity were not directly correlated in each area, their changes were significantly correlated, regardless of area type. Changes in central grid entropy were associated with changes in logarithm of the minimum angle of resolution visual acuity.Conclusion: Six months post RPE tear, entropy and retinal sensitivity increased in tear areas; entropy changes were linked to retinal sensitivity and visual acuity, indicating functional adjustments following the tear.","PeriodicalId":53580,"journal":{"name":"Retinal Cases and Brief Reports","volume":" ","pages":""},"PeriodicalIF":0.0,"publicationDate":"2025-03-31","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143774879","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

A case of successful ciliary body suture for recurrent membranous deposits around the intraocular lens in a patient with cyclodialysis. 睫状体缝合成功治疗睫状体透析患者睫状体周围复发性膜沉积一例。

Retinal Cases and Brief Reports Pub Date : 2025-03-31 DOI: 10.1097/ICB.0000000000001753

Mitsuru Otsubo, Kouji Takarada, Tatsurou Taneda, Yuki Kamiya, Taiji Nagaoka

引用次数: 0

SANDWICH TAMPONADE TECHNIQUE FOR THE MANAGEMENT OF GIANT RETINAL TEAR RETINAL DETACHMENT. 夹心填塞技术治疗巨大视网膜撕裂性视网膜脱离。

Retinal Cases and Brief Reports Pub Date : 2025-03-26 DOI: 10.1097/ICB.0000000000001751

Beatrice Gallo, Aman Chandra

{"title":"SANDWICH TAMPONADE TECHNIQUE FOR THE MANAGEMENT OF GIANT RETINAL TEAR RETINAL DETACHMENT.","authors":"Beatrice Gallo, Aman Chandra","doi":"10.1097/ICB.0000000000001751","DOIUrl":"https://doi.org/10.1097/ICB.0000000000001751","url":null,"abstract":"Purpose: Controversy exists regarding the best intraocular tamponade for the management of giant retinal tear rhegmatogenous retinal detachment (GRT-RRD). We describe the 'sandwich' technique for the short-term post-operative tamponade of RRD associated with GRT.Methods: Description of surgical technique and retrospective case series of eyes with GRT-RRD. Surgery consisted of 25-gauge pars plana vitrectomy (PPV) with heavy liquid (perfluoro-n-octane) and sulphur hexafluoride (100% SF6, 0.5 mL) gas used as post-operative intraocular tamponade, and removed after a mean of 11 (range 10-14) days with a second PPV with air tamponade.Results: three eyes of three patients (mean age 64 years) with GRT-RRD involving the inferior retina (2 fovea sparing and 1 fovea involving) were treated with PPV and 'sandwich' tamponade. In all cases best corrected visual acuity improved, successful retinal reattachment was achieved, and there were no intraoperative and post-operative complications.Conclusion: The 'sandwich' tamponade is a safe and effective short-term post-operative tamponade for GRT-RRD extending beyond the superior and inferior meridians. It has the advantage of providing tamponade to a large extensive GRT with no posturing requirement, and of avoiding ocular toxicity associated with the use of silicone oil.","PeriodicalId":53580,"journal":{"name":"Retinal Cases and Brief Reports","volume":" ","pages":""},"PeriodicalIF":0.0,"publicationDate":"2025-03-26","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143733194","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0