Suganeswari Ganesan, Henna V Valakkadavil, Charanya C
{"title":"玻璃体内抗血管内皮生长因子（雷尼单抗）后眼内炎表现为霜状支血管炎。","authors":"Suganeswari Ganesan, Henna V Valakkadavil, Charanya C","doi":"10.1097/ICB.0000000000001820","DOIUrl":null,"url":null,"abstract":"<p><strong>Purpose: </strong>To report a case of a 43-year-old female with post intravitreal injection endophthalmitis who presented with segmental perivascular sheathing simulating frosted branch angiitis.</p><p><strong>Methods: </strong>We promptly suspected and treated the atypical presentation of post anti-VEGF bacterial endophthalmitis with pars plana vitrectomy and intraocular and oral antibiotics.</p><p><strong>Results: </strong>Patient showed dramatic response to the treatment and made full visual recovery with resolution of clinical signs.</p><p><strong>Conclusion: </strong>Frosted branch angiitis (FBA), though typically associated with autoimmune conditions, malignancies, or certain viral infections, may also present as an early manifestation of bacterial endophthalmitis. Prompt initiation of treatment can significantly improve visual outcomes.</p>","PeriodicalId":53580,"journal":{"name":"Retinal Cases and Brief Reports","volume":" ","pages":""},"PeriodicalIF":0.0000,"publicationDate":"2025-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"0","resultStr":"{\"title\":\"Presentation of post intravitreal anti-Vascular Endothelial Growth Factor (ranibizumab) endophthalmitis as frosted branch angiitis.\",\"authors\":\"Suganeswari Ganesan, Henna V Valakkadavil, Charanya C\",\"doi\":\"10.1097/ICB.0000000000001820\",\"DOIUrl\":null,\"url\":null,\"abstract\":\"<p><strong>Purpose: </strong>To report a case of a 43-year-old female with post intravitreal injection endophthalmitis who presented with segmental perivascular sheathing simulating frosted branch angiitis.</p><p><strong>Methods: </strong>We promptly suspected and treated the atypical presentation of post anti-VEGF bacterial endophthalmitis with pars plana vitrectomy and intraocular and oral antibiotics.</p><p><strong>Results: </strong>Patient showed dramatic response to the treatment and made full visual recovery with resolution of clinical signs.</p><p><strong>Conclusion: </strong>Frosted branch angiitis (FBA), though typically associated with autoimmune conditions, malignancies, or certain viral infections, may also present as an early manifestation of bacterial endophthalmitis. Prompt initiation of treatment can significantly improve visual outcomes.</p>\",\"PeriodicalId\":53580,\"journal\":{\"name\":\"Retinal Cases and Brief Reports\",\"volume\":\" \",\"pages\":\"\"},\"PeriodicalIF\":0.0000,\"publicationDate\":\"2025-10-01\",\"publicationTypes\":\"Journal Article\",\"fieldsOfStudy\":null,\"isOpenAccess\":false,\"openAccessPdf\":\"\",\"citationCount\":\"0\",\"resultStr\":null,\"platform\":\"Semanticscholar\",\"paperid\":null,\"PeriodicalName\":\"Retinal Cases and Brief Reports\",\"FirstCategoryId\":\"1085\",\"ListUrlMain\":\"https://doi.org/10.1097/ICB.0000000000001820\",\"RegionNum\":0,\"RegionCategory\":null,\"ArticlePicture\":[],\"TitleCN\":null,\"AbstractTextCN\":null,\"PMCID\":null,\"EPubDate\":\"\",\"PubModel\":\"\",\"JCR\":\"Q3\",\"JCRName\":\"Medicine\",\"Score\":null,\"Total\":0}","platform":"Semanticscholar","paperid":null,"PeriodicalName":"Retinal Cases and Brief Reports","FirstCategoryId":"1085","ListUrlMain":"https://doi.org/10.1097/ICB.0000000000001820","RegionNum":0,"RegionCategory":null,"ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"Q3","JCRName":"Medicine","Score":null,"Total":0}
Presentation of post intravitreal anti-Vascular Endothelial Growth Factor (ranibizumab) endophthalmitis as frosted branch angiitis.
Purpose: To report a case of a 43-year-old female with post intravitreal injection endophthalmitis who presented with segmental perivascular sheathing simulating frosted branch angiitis.
Methods: We promptly suspected and treated the atypical presentation of post anti-VEGF bacterial endophthalmitis with pars plana vitrectomy and intraocular and oral antibiotics.
Results: Patient showed dramatic response to the treatment and made full visual recovery with resolution of clinical signs.
Conclusion: Frosted branch angiitis (FBA), though typically associated with autoimmune conditions, malignancies, or certain viral infections, may also present as an early manifestation of bacterial endophthalmitis. Prompt initiation of treatment can significantly improve visual outcomes.
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