Retinal Cases and Brief Reports最新文献_第2页

CHOROIDAL SYNPHLEBIA IN A PATIENT WITH CENTRAL SEROUS CHORIORETINOPATHY. 中枢性浆液性脉络膜视网膜病变患者的脉络膜综合征。

Retinal Cases and Brief Reports Pub Date : 2026-05-01 DOI: 10.1097/ICB.0000000000001728

Amirreza Naderi, Richard F Spaide

{"title":"CHOROIDAL SYNPHLEBIA IN A PATIENT WITH CENTRAL SEROUS CHORIORETINOPATHY.","authors":"Amirreza Naderi, Richard F Spaide","doi":"10.1097/ICB.0000000000001728","DOIUrl":"10.1097/ICB.0000000000001728","url":null,"abstract":"Purpose: The purpose of this study was to describe the choroidal vascular abnormality of conjoined choroidal vessels, synphlebia, in a patient with central serous chorioretinopathy.Methods: A patient initially referred for pigmentary retinal dystrophy later developed central serous retinopathy and underwent a comprehensive examination with multimodal imaging.Results: A 30-year-old man had an undiagnosed pigmentary retinopathy, and nyctalopia was found to have a dehydrodolichyl diphosphate synthase mutation, confirming a retinitis pigmentosa diagnosis. A year later, he presented with bilateral central serous chorioretinopathy. During the venous phase of indocyanine green angiography, individual vessels could not be differentiated in the posterior pole. Swept source optical coherence tomography revealed an abnormally thick choroid with enormous vascular channels that did not appear to have separation into individual tubular structures. These abnormal vessels nearly occupied the entire thickness of the choroid in the macular region. There was little sign of any intermediate-sized choroidal vessels in the posterior pole. A review of other patients with dehydrodolichyl diphosphate synthase mutation showed no similar choroidal vascular changes.Conclusion: Large, conjoined veins, which we termed synphlebia, were seen in an eye with central serous chorioretinopathy. Loading of the choriocapillaris from these enlarged vascular channels may have contributed to hyperpermeability and formation of serous fluid. Observation of this choroidal vascular pattern suggests that a central serous chorioretinopathy phenotype may develop through more than one pathway.","PeriodicalId":53580,"journal":{"name":"Retinal Cases and Brief Reports","volume":" ","pages":"289-293"},"PeriodicalIF":0.0,"publicationDate":"2026-05-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143392573","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

OCCULT INVASIVE FUNGAL SINUSITIS IN A PATIENT WITH ACUTE VOGT-KOYANAGI-HARADA DISEASE. 急性Vogt-Koyanagi-Harada病隐匿性侵袭性鼻窦炎1例。

Retinal Cases and Brief Reports Pub Date : 2026-05-01 DOI: 10.1097/ICB.0000000000001754

Emily C Davis, Akshay S Thomas

{"title":"OCCULT INVASIVE FUNGAL SINUSITIS IN A PATIENT WITH ACUTE VOGT-KOYANAGI-HARADA DISEASE.","authors":"Emily C Davis, Akshay S Thomas","doi":"10.1097/ICB.0000000000001754","DOIUrl":"10.1097/ICB.0000000000001754","url":null,"abstract":"Purpose: We present a case of the development of invasive fungal sinusitis in a patient with acute Vogt-Koyanagi-Harada Disease (VKHD).Methods: Observational case report.Results: A 39-year-old African American woman presented with acute vision loss in both eyes and reported pain around her left eye. Examination revealed a bilateral posterior uveitis with significant macular edema and subretinal fluid in both eyes. Systemic and ocular findings were consistent with complete VKHD and the patient was put on oral glucocorticoids. At follow-up 2 weeks later, blood sugars were found to be severely elevated, and the patient was hospitalized. During hospitalization, the patient was taken off steroids. At follow-up, the uveitis appeared quiescent, but vision was still poor in the left eye. The patient reported a continued sense of pressure and now numbness around the left eye. An MRI revealed occult invasive fungal sinusitis and the patient was hospitalized for treatment. The patient recovered after surgery for debridement of the sinuses and several weeks of treatment with amphotericin B. At the most recent follow-up, 18 months after the initial visit, the patient's VA was 20/20 OD and 20/50 with eccentric viewing OS.Conclusion: Many forms of uveitis such as acute VKHD require use of oral glucocorticoids. However, proper use of glucocorticoids involves patient counseling on potential side effects and the prescribing physician to identify potential life-threatening complications. In this case, failure to identify either the severely elevated blood sugars or occult fungal sinusitis could have resulted in significant patient morbidity or even mortality.","PeriodicalId":53580,"journal":{"name":"Retinal Cases and Brief Reports","volume":" ","pages":"457-461"},"PeriodicalIF":0.0,"publicationDate":"2026-05-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143774878","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

A NOVEL CASE STUDY OF UNILATERAL SEROUS RETINAL DETACHMENT IN A GLAUCOMA PATIENT WITH NEPHROTIC SYNDROME. 肾病综合征青光眼患者单侧浆液性视网膜脱离的新病例研究。

Retinal Cases and Brief Reports Pub Date : 2026-05-01 DOI: 10.1097/ICB.0000000000001755

Robert D Nguyen, Martin Dionson, Emmanuel Agu, John A Gonzales

{"title":"A NOVEL CASE STUDY OF UNILATERAL SEROUS RETINAL DETACHMENT IN A GLAUCOMA PATIENT WITH NEPHROTIC SYNDROME.","authors":"Robert D Nguyen, Martin Dionson, Emmanuel Agu, John A Gonzales","doi":"10.1097/ICB.0000000000001755","DOIUrl":"10.1097/ICB.0000000000001755","url":null,"abstract":"Purpose: To present a case of a unilateral serous retinal detachment in a patient with nephrotic syndrome after Ahmed valve implantation.Methods: Retrospective descriptive case report.Results: A 63-year-old man with a history of Ahmed valve implantation, diabetes, and hypertension presented with progressive corneal edema and decreased vison who developed a serous retinal detachment in the right eye. There was no view of the fundus because of the massive retinal detachment. B-scan ultrasonography revealed a serous retinal detachment with mild choroidal thickening. Along with the development of anasarca, laboratory testing revealed significant proteinuria and hypoalbuminemia, consistent with nephrotic syndrome. Fluid restriction and treatment with diuretics and antihypertensives resulted in rapid resolution of the serous retinal detachment.Conclusion: Although nephrotic syndrome can cause central serous retinal detachment, the presentation is almost always bilateral. A unilateral serous retinal detachment presentation can occur in patients with risk factors such as a history of Ahmed valve implantation and conditions that alter intravascular fluid hydrostatic and oncotic pressures. Prompt recognition of nephrotic syndrome in patients with kidney disease who develop serous retinal detachment is critical. Early treatment with diuretic therapy can significantly resolve ocular complications and potentially improve patient outcomes.","PeriodicalId":53580,"journal":{"name":"Retinal Cases and Brief Reports","volume":" ","pages":"401-405"},"PeriodicalIF":0.0,"publicationDate":"2026-05-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143784500","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

A HEAD-TO-HEAD COMPARISON OF EFFICIENCY IN TWO MODERN VITREORETINAL SURGERY PLATFORMS. 两种现代玻璃体视网膜手术平台的疗效比较。

Retinal Cases and Brief Reports Pub Date : 2026-05-01 DOI: 10.1097/ICB.0000000000001878

Federica Mirabella, Nicola C D'Onofrio, Stanislao Rizzo

引用次数: 0

POLARIZATION-SENSITIVE OPTICAL COHERENCE TOMOGRAPHY FEATURES OF THE REPAIR TISSUE AFTER RETINAL PIGMENT EPITHELIUM TEAR AND FUNCTIONAL CORRELATION WITH VISUAL OUTCOMES. 视网膜色素上皮撕裂后修复组织的偏振敏感光学相干断层扫描特征及其与视力结果的功能相关性。

Retinal Cases and Brief Reports Pub Date : 2026-05-01 DOI: 10.1097/ICB.0000000000001752

Keiko Azuma, Daisuke Santo, Satoshi Sugiyama, Nobuyori Aoki, Shuichiro Aoki, Kohdai Kitamoto, Ryo Terao, Tatsuya Inoue, Ryo Obata

{"title":"POLARIZATION-SENSITIVE OPTICAL COHERENCE TOMOGRAPHY FEATURES OF THE REPAIR TISSUE AFTER RETINAL PIGMENT EPITHELIUM TEAR AND FUNCTIONAL CORRELATION WITH VISUAL OUTCOMES.","authors":"Keiko Azuma, Daisuke Santo, Satoshi Sugiyama, Nobuyori Aoki, Shuichiro Aoki, Kohdai Kitamoto, Ryo Terao, Tatsuya Inoue, Ryo Obata","doi":"10.1097/ICB.0000000000001752","DOIUrl":"10.1097/ICB.0000000000001752","url":null,"abstract":"Purpose: To investigate changes in melanin distribution and retinal sensitivity after a retinal pigment epithelium tear in neovascular age-related macular degeneration.Methods: Five cases of neovascular age-related macular degeneration with retinal pigment epithelium tears involving the fovea within 1 month of onset were examined. Using polarization-sensitive optical coherence tomography, entropy-a quantitative indicator of melanin distribution-was measured at baseline and 6 months at the level of Bruch membrane. Retinal sensitivity was assessed with a microperimeter, and entropy was averaged across 25 grids within a 6° radius. The relationship between changes in entropy and retinal sensitivity was analyzed.Results: Entropy significantly increased in the tear area (from 0.18 to 0.22, P< 0.0001), whereas it decreased in the nontear area. Retinal sensitivity also significantly increased in the tear area (from 12.7 to 16.3 dB, P <0.0001). Although entropy and retinal sensitivity were not directly correlated in each area, their changes were significantly correlated, regardless of area type. Changes in central grid entropy were associated with changes in logarithm of the minimum angle of resolution visual acuity.Conclusion: Six months postretinal pigment epithelium tear, entropy and retinal sensitivity increased in tear areas; entropy changes were linked to retinal sensitivity and visual acuity, indicating functional adjustments after the tear.","PeriodicalId":53580,"journal":{"name":"Retinal Cases and Brief Reports","volume":" ","pages":"423-429"},"PeriodicalIF":0.0,"publicationDate":"2026-05-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143774879","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

ACTIVE EXTERNAL DRAINAGE OF SUBRETINAL FLUID WITHOUT VITRECTOMY TO TREAT ADVANCED COATS DISEASE WITH EXUDATIVE RETINAL DETACHMENT-A CASE REPORT AND LITERATURE REVIEW. 主动外引流视网膜下液治疗晚期Coats病伴渗出性视网膜脱离1例并文献复习。

Retinal Cases and Brief Reports Pub Date : 2026-05-01 DOI: 10.1097/ICB.0000000000001745

Prabu Baskaran, Savithri Palanivel, Yeshwanth Kumar

引用次数: 0

A CASE OF UVEAL MELANOMA MASQUERADING AS CHOROIDAL LYMPHOMA. 葡萄膜黑色素瘤伪装成脉络膜淋巴瘤1例。

Retinal Cases and Brief Reports Pub Date : 2026-05-01 DOI: 10.1097/ICB.0000000000001738

Sahal H Saleh, Rima Stepanian, Joseph D Juliano, Robert Folberg, Lau-Sickon Laurie, Lisa J Faia, Adam J Weiner

{"title":"A CASE OF UVEAL MELANOMA MASQUERADING AS CHOROIDAL LYMPHOMA.","authors":"Sahal H Saleh, Rima Stepanian, Joseph D Juliano, Robert Folberg, Lau-Sickon Laurie, Lisa J Faia, Adam J Weiner","doi":"10.1097/ICB.0000000000001738","DOIUrl":"10.1097/ICB.0000000000001738","url":null,"abstract":"Purpose: To present a case of uveal melanoma masquerading as choroidal lymphoma.Methods: A retrospective case report in which medical and imaging records, including fundus photography, optical coherence tomography, fundus autofluorescence, fluorescein angiography, and ultrasonography, were reviewed.Results: A 77-year-old woman presenting with decreased vision was found to have a diffuse, shallow, yellow choroidal mass associated with retinal pigment epithelium pigmentary changes and exudative detachment in her right eye. Multimodal imaging demonstrated thickened choroid with a \"lumpy-bumpy\" appearance on optical coherence tomography, \"leopard-spotting\" on fundus autofluorescence, and a shallow \"table-top\" configuration on B scan. Systemic workup was unremarkable. The patient elected to undergo treatment with low-dose external beam radiation for presumed choroidal lymphoma. There was no response to radiation prompting retinochoroidal biopsy, which revealed spindle-cell uveal melanoma and resulted in enucleation.Conclusion: We present a case of uveal melanoma masquerading as choroidal lymphoma. This case highlights that uveal melanoma can rarely masquerade as other entities, including uveal lymphoma.","PeriodicalId":53580,"journal":{"name":"Retinal Cases and Brief Reports","volume":" ","pages":"364-368"},"PeriodicalIF":0.0,"publicationDate":"2026-05-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143473179","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

INFUSION-INDUCED MACULAR HOLES IN PARS PLANA VITRECTOMY: A CASE SERIES OF SIX PATIENTS. 玻璃体部分切除术中输液引起的黄斑孔洞：附6例病例分析。

Retinal Cases and Brief Reports Pub Date : 2026-05-01 DOI: 10.1097/ICB.0000000000001731

Hannah Shuman, Vichar Trivedi, Dhir Patwa, Patrick S Y Lee, David V Tran, Jacob Im, Rao Me, Jack Komro, Chinwenwa Okeagu, Kim Le, Xihui Lin

{"title":"INFUSION-INDUCED MACULAR HOLES IN PARS PLANA VITRECTOMY: A CASE SERIES OF SIX PATIENTS.","authors":"Hannah Shuman, Vichar Trivedi, Dhir Patwa, Patrick S Y Lee, David V Tran, Jacob Im, Rao Me, Jack Komro, Chinwenwa Okeagu, Kim Le, Xihui Lin","doi":"10.1097/ICB.0000000000001731","DOIUrl":"10.1097/ICB.0000000000001731","url":null,"abstract":"Purpose: The purpose of this study was to describe a series of six cases in which iatrogenic macular holes were induced by the infusion fluid flow of a 25-gauge pars plana vitrectomy system.Methods: This is a retrospective case series of six patients treated at Kresge Eye Institute between 2018 and 2024.Results: Iatrogenic macular holes caused by infusion fluid flow are a rare complication of pars plana vitrectomy. In this series, five of six patients had a history of diabetes mellitus and proliferative diabetic retinopathy. Most of these patients were undergoing repair of tractional retinal detachments when the complication occurred. The average patient age was 47 years (range: 32-66 years). Four patients were pseudophakic, and only one had undergone prior vitrectomy. Preoperative visual acuity ranged from 20/50 to hand motion, while postoperative visual acuity ranged from 20/80 to hand motion. Two patients experienced an improvement in visual acuity postoperatively.Conclusion: This case series highlights the potential risk of macular hole formation due to infusion fluid dynamics during pars plana vitrectomy. In diabetic patients with tractional retinal detachments or significant macular ischemia, we recommend positioning the infusion cannula away from the posterior pole to mitigate the risk of this complication.","PeriodicalId":53580,"journal":{"name":"Retinal Cases and Brief Reports","volume":" ","pages":"332-335"},"PeriodicalIF":0.0,"publicationDate":"2026-05-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143400509","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

CHORIORETINITIS AFTER BACILLUS CALMETTE-GUERIN TREATMENT FOR BLADDER CANCER. 卡介苗治疗膀胱癌后的绒毛膜视网膜炎。

Retinal Cases and Brief Reports Pub Date : 2026-05-01 DOI: 10.1097/ICB.0000000000001736

Nithya Boopathiraj, Isabella V Wagner, Ross Powers, Arman Mashayekhi

{"title":"CHORIORETINITIS AFTER BACILLUS CALMETTE-GUERIN TREATMENT FOR BLADDER CANCER.","authors":"Nithya Boopathiraj, Isabella V Wagner, Ross Powers, Arman Mashayekhi","doi":"10.1097/ICB.0000000000001736","DOIUrl":"10.1097/ICB.0000000000001736","url":null,"abstract":"Purpose: To report a rare case of multifocal chorioretinitis subsequent to intravesical Bacillus Calmette-Guerin therapy for bladder cancer.Methods: Case report.Results: A 74-year-old man presented with ill-defined visual changes in his right eye, along with constitutional symptoms such as low-grade fever, chills with rigors, night sweats, headache, dry cough, memory problems, and unintentional weight loss. These symptoms occurred 11 months after receiving intravesical Bacillus Calmette-Guerin treatment for bladder cancer. His visual acuity in the right eye was 20/30. Examination of his right eye revealed multiple yellow white chorioretinal lesions, and optical coherence tomography imaging showed focal involvement of the choroid and overlying neurosensory retina. Blood-based testing using next-generation sequencing for detection of microbial cell free DNA (Karius test) was positive for Mycobacterium tuberculosis complex. The patient was treated with 12 months of triple therapy consisting of isoniazid, rifampin, and ethambutol. The chorioretinal lesions showed complete regression to flat scars, with no evidence of recurrence 15 months after discontinuation of systemic treatment.Conclusion: Despite being rare, the possibility of mycobacterial chorioretinitis should be considered in patients with new-onset visual symptoms after intravesical Bacillus Calmette-Guerin treatment for bladder cancer.","PeriodicalId":53580,"journal":{"name":"Retinal Cases and Brief Reports","volume":" ","pages":"351-354"},"PeriodicalIF":0.0,"publicationDate":"2026-05-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143473180","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

BILATERAL GIANT RETINAL TEAR DETACHMENTS IN AN INFANT WITH DONNAI-BARROW SYNDROME: A CASE REPORT AND REVIEW OF LITERATURE. 多奈-巴罗综合征婴儿双侧巨大视网膜撕裂脱离一例报告及文献复习。

Retinal Cases and Brief Reports Pub Date : 2026-05-01 DOI: 10.1097/ICB.0000000000001744

Alan Y Huang, Sonny Caplash, Drew Scoles

{"title":"BILATERAL GIANT RETINAL TEAR DETACHMENTS IN AN INFANT WITH DONNAI-BARROW SYNDROME: A CASE REPORT AND REVIEW OF LITERATURE.","authors":"Alan Y Huang, Sonny Caplash, Drew Scoles","doi":"10.1097/ICB.0000000000001744","DOIUrl":"10.1097/ICB.0000000000001744","url":null,"abstract":"Purpose: The objective of this study was to report a rare case of bilateral giant retinal tear-related retinal detachments in a 24-month-old man with Donnai-Barrow syndrome (DBS) and to review the current literature on this disorder.Methods: Clinical information was obtained from the medical records of a patient with DBS seen at the Children's Hospital of Philadelphia. A literature review was conducted to identify all published cases of genetically or clinically diagnosed DBS.Results: We report a case of a 24-month-old man with a history of DBS presenting with sudden loss of vision in both eyes. Ophthalmic examination revealed bilateral retinal detachments with giant retinal tears, complicated by grade C proliferative vitreoretinopathy in the right eye. The patient underwent sequential scleral buckling, pars plana vitrectomy, membrane peeling, perfluoron, endolaser, fluid-air exchange, and silicone oil placement in both eyes. Both eyes developed redetachment, requiring repeat pars plana vitrectomy. Literature review revealed 10 reported cases of retinal detachments out of 38 patients with DBS who survived past 1 year (26.3%).Conclusion: This case highlights the early presentation and complexity of giant retinal tear-related retinal detachment in patients with DBS. Early, aggressive management using prophylactic laser retinopexy or scleral buckling may be essential in improving visual outcomes in patients with DBS.","PeriodicalId":53580,"journal":{"name":"Retinal Cases and Brief Reports","volume":" ","pages":"375-383"},"PeriodicalIF":0.0,"publicationDate":"2026-05-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143527979","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0