Retinal Cases and Brief Reports最新文献_第2页

LATE DIAGNOSIS OF Cutibacterium acnes (FORMERLY Propionibacterium acnes ) ENDOPHTHALMITIS AND THE IMPORTANCE OF DUAL TESTING WITH BACTERIAL CULTURE AND POLYMERASE CHAIN REACTION. 痤疮棒状杆菌（原痤疮丙酸杆菌）眼底病的晚期诊断以及细菌培养和聚合酶链反应双重检测的重要性。

Retinal Cases and Brief Reports Pub Date : 2024-09-01 DOI: 10.1097/ICB.0000000000001458

Christopher R Rosenberg, Rebekah H Gensure, David Tri Ta Kim, Marika Yumang, Eric B Suhler, Phoebe Lin, Christina J Flaxel

{"title":"LATE DIAGNOSIS OF Cutibacterium acnes (FORMERLY Propionibacterium acnes ) ENDOPHTHALMITIS AND THE IMPORTANCE OF DUAL TESTING WITH BACTERIAL CULTURE AND POLYMERASE CHAIN REACTION.","authors":"Christopher R Rosenberg, Rebekah H Gensure, David Tri Ta Kim, Marika Yumang, Eric B Suhler, Phoebe Lin, Christina J Flaxel","doi":"10.1097/ICB.0000000000001458","DOIUrl":"10.1097/ICB.0000000000001458","url":null,"abstract":"Purpose: The purpose of this study was to describe two cases of Cutibacterium acnes endophthalmitis that reinforce the importance of performing both bacterial culture and 16S polymerase chain reaction when the causative pathogen is unclear or difficult to culture, such as C. acnes . A case of C. acnes endophthalmitis complicated by subbuckle scleral perforation is illustrated with intraoperative photography.Methods: This is a two-case series.Results: Case 1 describes a case of C. acnes endophthalmitis in a longstanding pseudophakic patient after multiple vitrectomies for recurrent retinal detachment, complicated by subbuckle scleral perforation. Bacterial culture revealed C. acnes while 16S PCR was negative. Conversely, Case 2 demonstrates a case of chronic endophthalmitis diagnosed one year after cataract surgery. PCR (with repeat tap for confirmation) revealed C. acnes with a negative culture.Conclusion: When the causative pathogen of endophthalmitis is unclear, dual testing of microbial culture and C. acnes 16S PCR improves the diagnostic yield of investigations for fastidious pathogens. C. acnes can present as an indolent or virulent endophthalmitis.","PeriodicalId":53580,"journal":{"name":"Retinal Cases and Brief Reports","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2024-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10909904/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"10189893","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

HYPERACUTE CUTIBACTERIUM ACNES ENDOPHTHALMITIS AFTER CATARACT SURGERY. 白内障手术后的急性痤疮杆菌眼内炎。

Retinal Cases and Brief Reports Pub Date : 2024-09-01 DOI: 10.1097/ICB.0000000000001450

Blake M Hauser, Sandra Hoyek, Scott H Greenstein, Nimesh A Patel

{"title":"HYPERACUTE CUTIBACTERIUM ACNES ENDOPHTHALMITIS AFTER CATARACT SURGERY.","authors":"Blake M Hauser, Sandra Hoyek, Scott H Greenstein, Nimesh A Patel","doi":"10.1097/ICB.0000000000001450","DOIUrl":"https://doi.org/10.1097/ICB.0000000000001450","url":null,"abstract":"Purpose: Postoperative endophthalmitis is a relatively uncommon, but potentially visually devastating, complication associated with cataract surgery. Specific microbial causes of endophthalmitis are characteristically associated with particular disease time courses. Although Cutibacterium acnes is typically associated with an indolent course of inflammation, we report a case of C. acnes endophthalmitis with onset on postoperative day (POD) 1 and a positive culture from POD 2.Methods: This is a case report.Results: A 56-year-old man underwent cataract extraction and posterior chamber intraocular lens placement in his left eye. On POD 1, he presented with severe discomfort, reduced visual acuity, and significant inflammation. On POD 2, his anterior chamber was tapped and injected with broad-spectrum antibiotics and steroids. The inflammation ultimately resolved, and his visual acuity improved to 20/20.Conclusion: C. acnes is a rare cause of hyperacute-onset postoperative endophthalmitis. Maintaining a high clinical suspicion and initiating prompt treatment can help to optimize long-term visual outcomes.","PeriodicalId":53580,"journal":{"name":"Retinal Cases and Brief Reports","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2024-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142300764","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

FOVEA PLANA AND FUNDUS HYPOPIGMENTATION IN PRADER-WILLI SYNDROME. 普拉德-威利综合征的眼底和眼窝色素沉着。

Retinal Cases and Brief Reports Pub Date : 2024-09-01 DOI: 10.1097/ICB.0000000000001441

Priscille de Laage de Meux, Héléna Mosbah, Anne Cotton-Viard, Salomon Y Cohen

引用次数: 0

MULTIPLYING BROWN SPOTS. 褐斑增多。

Retinal Cases and Brief Reports Pub Date : 2024-09-01 DOI: 10.1097/ICB.0000000000001443

Amer F Alsoudi, Matthew N Parvus, Jose Pulido, Patricia Chevez-Barrios, Bin S Teh, Eric Bernicker, Sarah Miles, Amy Schefler

{"title":"MULTIPLYING BROWN SPOTS.","authors":"Amer F Alsoudi, Matthew N Parvus, Jose Pulido, Patricia Chevez-Barrios, Bin S Teh, Eric Bernicker, Sarah Miles, Amy Schefler","doi":"10.1097/ICB.0000000000001443","DOIUrl":"10.1097/ICB.0000000000001443","url":null,"abstract":"Background/purpose: Bilateral diffuse uveal melanocytic proliferation is a paraneoplastic syndrome affecting the eye that is a sign of poor prognosis of underlying malignancy. This is the first documented case to show serial and sustained improvement of bilateral diffuse uveal melanocytic proliferation after immunotherapy in the setting of primary non-small-cell carcinoma of the lung.Methods: Single-center, case report.Results: A 65-year-old man reported a gradual decrease in vision and floaters in the right eye after cataract surgery. Fundus examination demonstrated diffuse multiple brown subretinal lesions bilaterally. Next-generation sequencing of melanocytic tissue of the patient described in this case revealed a specific RB1 c.411A>T (p.Glu137Asp) variant with an allele frequency of 44.8%, consistent with heterozygosity. Plasma samples from the patient and a control patient with no history of cancer and/or paraneoplastic syndrome were cultured with neonatal melanocytes, which revealed a >180% increase in proliferation of normal neonatal melanocytes compared with the control. Pembrolizumab therapy was initiated, which resulted in shrinkage and stabilization of the lesions documented in serial diagnostic testing.Conclusion: In conclusion, we report a cytologically and serologically confirmed case of bilateral diffuse uveal melanocytic proliferation in a patient with a primary non-small-cell carcinoma of the lung. Next-generation sequencing of melanocytic tissue of the patient described in this case revealed a specific RB1 c.411A>T (p.Glu137Asp) variant with an allele frequency of 44.8%, consistent with heterozygosity. Furthermore, we show documented serial improvement in the patient's ocular and systemic disease with treatment. This case as one of the longest surviving confirmed cases of a patient with bilateral diffuse uveal melanocytic proliferation.","PeriodicalId":53580,"journal":{"name":"Retinal Cases and Brief Reports","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2024-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"9621800","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

PNEUMATIC DISPLACEMENT OF HEMORRHAGIC BACILLARY LAYER DETACHMENT. 出血性杆菌层脱落的气动移位。

Retinal Cases and Brief Reports Pub Date : 2024-09-01 DOI: 10.1097/ICB.0000000000001463

David R B Alderman, Peter Bracha

引用次数: 0

USE OF ADDITIONAL FACEDOWN POSITIONING WITH SILICONE OIL TAMPONADE FOR THE TREATMENT OF RETINAL REDETACHMENT. 使用额外的面朝下定位和硅油填塞法治疗视网膜剥离。

Retinal Cases and Brief Reports Pub Date : 2024-09-01 DOI: 10.1097/ICB.0000000000001461

Aditya Somisetty, Sandra Hoyek, Melissa Yuan, Swathi Somisetty, Leo A Kim, Nimesh A Patel

{"title":"USE OF ADDITIONAL FACEDOWN POSITIONING WITH SILICONE OIL TAMPONADE FOR THE TREATMENT OF RETINAL REDETACHMENT.","authors":"Aditya Somisetty, Sandra Hoyek, Melissa Yuan, Swathi Somisetty, Leo A Kim, Nimesh A Patel","doi":"10.1097/ICB.0000000000001461","DOIUrl":"10.1097/ICB.0000000000001461","url":null,"abstract":"Purpose: The purpose of this study was to highlight a potential alternative to additional surgery for management of retinal redetachment through the use of additional facedown positioning with silicone oil tamponade.Methods: Retrospective case series of two patients evaluated with examination, multimodal imaging, including fundus photography, optical coherence tomography, and fluorescein angiography.Results: In Case 1, a 70-year-old female patient underwent surgery for a full-thickness macular hole with associated macula-off retinal detachment, but experienced a recurrent detachment and underwent a second surgery with silicone oil placement. Another recurrent detachment was found. The case was managed conservatively with facedown positioning, resulting in resolution of subretinal fluid and improvement in vision. At follow-up, the retina remained attached with stable vision. In Case 2, a 25-year-old male patient underwent a surgical repair for proliferative vitreoretinopathy retinal detachment with a scleral buckle, cryotherapy, and external drainage. After multiple redetachment surgeries with retinectomy and oil placement, another tractional redetachment of the fovea was noted. Management was with facedown positioning, and follow-up evaluation showed resolution of the subretinal fluid and improvement in vision with stability for greater than 2 months.Conclusion: For recurrent retinal redetachments with silicone oil in place, an additional week of facedown positioning can result in anatomical success and be a viable alternative or bridge to invasive surgical interventions. This approach may have greatest utility for patients who are poor surgical candidates without new peripheral pathology.","PeriodicalId":53580,"journal":{"name":"Retinal Cases and Brief Reports","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2024-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"10228664","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

MACULAR SLING: A CUSTOMIZABLE METHOD FOR MACULAR BUCKLING USING AVAILABLE ELEMENTS. 黄斑吊带:一种可定制的方法黄斑屈曲使用可用的元素。

Retinal Cases and Brief Reports Pub Date : 2024-09-01 DOI: 10.1097/ICB.0000000000001438

Andrew Clark, Erik A Souverein, Daniel B Rootman, Dong Yang, Allan E Kreiger, Aaron Nagiel

{"title":"MACULAR SLING: A CUSTOMIZABLE METHOD FOR MACULAR BUCKLING USING AVAILABLE ELEMENTS.","authors":"Andrew Clark, Erik A Souverein, Daniel B Rootman, Dong Yang, Allan E Kreiger, Aaron Nagiel","doi":"10.1097/ICB.0000000000001438","DOIUrl":"10.1097/ICB.0000000000001438","url":null,"abstract":"Purpose: Macular buckling surgery is used to treat certain cases of myopic traction maculopathy but is rarely performed in the United States. One of the main factors limiting its use is the lack of commercially available buckling elements. Here, we describe a novel technique for creating an effective macular buckle using readily obtainable buckling materials.Methods: By using a traditional circumferential 41 band as the anchoring point around the globe, a 240 band can then be attached and oriented posteriorly along the superonasal-inferotemporal axis. This posterior 240 band is then used to guide a grooved sponge (509G) under the macula to create a customizable and titratable tamponade effect along the posterior pole. This approach was used to provide external support in the case of a recurrent, complex tractional retinal detachment which had failed multiple prior vitrectomy-based repairs.Results: Placement of the macular sling resolved the patient's recurrent retinal detachment with return of the visual acuity to her preoperative baseline. There have been no adverse effects related to the surgery aside from a large hyperopic shift due to the buckle effect on the macula. We believe the technical and material complexity of this technique is comparable with that of more common scleral buckling techniques.Conclusion: This macular sling technique can be used to create an effective posterior buckle without requiring specialized materials.","PeriodicalId":53580,"journal":{"name":"Retinal Cases and Brief Reports","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2024-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10663378/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"9570458","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

TECLISTAMAB-ASSOCIATED SCLEROUVEITIS WITH HYPOPYON. 特克司他单抗相关性硬膜炎伴有眼睑下垂。

Retinal Cases and Brief Reports Pub Date : 2024-09-01 DOI: 10.1097/ICB.0000000000001449

Tianyu Liu, Turner Schwartz, Apoorv P Chebolu, Jonathan C Tsui, Nirali Bhatt, Drew Scoles

引用次数: 0

SPONTANEOUS IMPROVEMENT OF MYOPIC RETINOSCHISIS AFTER A LONG-TERM OBSERVATIONAL PERIOD: A CASE SERIES. 经过长期观察，近视性视网膜裂孔自发好转：病例系列。

Retinal Cases and Brief Reports Pub Date : 2024-09-01 DOI: 10.1097/ICB.0000000000001453

Musse Hussein, Olufunmilola Adeleye, Olufemi E Adams, Guneet S Sodhi, Zeeshan Haq, Polly A Quiram, Peter H Tang, Edwin H Ryan

{"title":"SPONTANEOUS IMPROVEMENT OF MYOPIC RETINOSCHISIS AFTER A LONG-TERM OBSERVATIONAL PERIOD: A CASE SERIES.","authors":"Musse Hussein, Olufunmilola Adeleye, Olufemi E Adams, Guneet S Sodhi, Zeeshan Haq, Polly A Quiram, Peter H Tang, Edwin H Ryan","doi":"10.1097/ICB.0000000000001453","DOIUrl":"10.1097/ICB.0000000000001453","url":null,"abstract":"Purpose: To highlight spontaneous resolution or improvement of myopic retinoschisis (MR) in actively surveilled patients.Methods: Case series of five patients diagnosed with MR who did not undergo pars plana vitrectomy and were carefully monitored by a single retina specialist. Ocular and medical history were reviewed, and clinical characteristics including visual acuity and the status of the MR were monitored with spectral domain optical coherence tomography (SD-OCT) at each clinic visit.Results: Five patients were identified to have MR without vitreomacular traction, or macular hole formation. Two patients exhibited spontaneous and complete resolution of MR without surgical intervention over an average observation time of 52.5 months. In these cases, a clinical posterior vitreous detachment was documented preceding the resolution of MR over an average time of 26.5 months. Snellen best-corrected visual acuity in these patients improved (Case 1 from 20/50 to 20/40, Case 2 from 20/30 to 20/25). The remaining three patients were monitored for an average of 52 months and showed improvement of MR via OCT imaging. Snellen best-corrected visual acuity either remained stable or improved from baseline (Case 3 stable at 20/30, Case 4 improved from 20/40 to 20/30, and Case 5 stable at 20/20).Conclusion: These findings suggest that conservative management of MR with observation can be considered especially in patients with challenging comorbidities (such as monocular status), and with a clinically identified posterior vitreous detachment without vitreomacular traction.","PeriodicalId":53580,"journal":{"name":"Retinal Cases and Brief Reports","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2024-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"9831417","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

RETINAL DIALYSIS AND ASSOCIATED RHEGMATOGENOUS RETINAL DETACHMENT IN PATIENTS WITH NEUROFIBROMATOSIS TYPE 1: A CASE SERIES. 神经纤维瘤病 1 型患者的视网膜透析和相关流变性视网膜脱离：病例系列。

Retinal Cases and Brief Reports Pub Date : 2024-09-01 DOI: 10.1097/ICB.0000000000001455

Ronak M Shah, Robin A Vora, Amar P Patel

{"title":"RETINAL DIALYSIS AND ASSOCIATED RHEGMATOGENOUS RETINAL DETACHMENT IN PATIENTS WITH NEUROFIBROMATOSIS TYPE 1: A CASE SERIES.","authors":"Ronak M Shah, Robin A Vora, Amar P Patel","doi":"10.1097/ICB.0000000000001455","DOIUrl":"10.1097/ICB.0000000000001455","url":null,"abstract":"Purpose: Although ophthalmic manifestations of neurofibromatosis Type 1 (NF1), including iris Lisch nodules and optic gliomas, have been well described, retinal involvement in these patients has yet to be established. Characterizing the relationship between NF1 and the retina is necessary to optimize outcomes for these patients.Methods: Independent chart review of NF1 patients was conducted.Results: Chart review yielded four patients, with a history of NF1, with subsequent retinal dialysis and rhegmatogenous retinal detachment. These four patients presented to our institution with a rhegmatogenous retinal detachment secondary to a retinal dialysis with no history of trauma. These patients also demonstrated hyperreflective choroidal abnormalities on near-infrared reflectance imaging and optical coherence tomography.Conclusion: Seeing that patients diagnosed with NF1 are susceptible to various ocular manifestations and pathological abnormalities, routine ophthalmic examinations are essential in maintaining their ocular health and minimizing morbidity.","PeriodicalId":53580,"journal":{"name":"Retinal Cases and Brief Reports","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2024-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"9833871","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0