Retinal Cases and Brief Reports最新文献_第2页

HEMORRHAGIC UNILATERAL RETINOPATHY: A REPORT OF MULTIMODAL IMAGING IN THREE CASES. 出血性单侧视网膜病变：三例多模态成像报告。

Retinal Cases and Brief Reports Pub Date : 2025-05-01 DOI: 10.1097/ICB.0000000000001557

Nuria Torrell-Belzach, Alexandra Miere, Eric H Souied, Alain Gaudric, Salomon Y Cohen

{"title":"HEMORRHAGIC UNILATERAL RETINOPATHY: A REPORT OF MULTIMODAL IMAGING IN THREE CASES.","authors":"Nuria Torrell-Belzach, Alexandra Miere, Eric H Souied, Alain Gaudric, Salomon Y Cohen","doi":"10.1097/ICB.0000000000001557","DOIUrl":"10.1097/ICB.0000000000001557","url":null,"abstract":"Purpose: The objective of this study was to report three cases of hemorrhagic unilateral retinopathy, diagnosed by multimodal imaging.Methods: This was a case report of three patients, two women and one man, aged 51, 74, and 52 years, respectively.Results: Symptoms were acute floaters, blurred vision, or central scotoma, unilateral in all cases. The best-corrected visual acuity was 20/20 in the affected eye in two patients with a paracentral scotoma and 20/160 in the third patient. Funduscopic examination revealed multiple unilateral posterior hemorrhages located in the Henle fiber layer in the macula and beneath the internal limiting membrane around the optic disc on spectral domain optical coherence tomography. Fluorescein angiography and indocyanine green angiography did not show any vascular abnormalities. Spectral domain optical coherence tomography angiography did not show any capillary dropout or choroidal abnormalities. In all patients, the visual symptoms completely disappeared within a few weeks, with spontaneous regression of the hemorrhages.Conclusion: Hemorrhagic unilateral retinopathy is a rarely reported and poorly understood disorder. Indocyanine green angiography and spectral domain optical coherence tomography angiography did not allow better understanding the condition. No etiology has been associated with this entity so far. The spontaneous resolution of the present cases confirmed the favorable visual prognosis of the condition.","PeriodicalId":53580,"journal":{"name":"Retinal Cases and Brief Reports","volume":" ","pages":"358-362"},"PeriodicalIF":0.0,"publicationDate":"2025-05-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140013746","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

EARLY RETINAL MANIFESTATIONS PRECEDING ACUTE SYPHILITIC POSTERIOR PLACOID CHORIORETINITIS. 急性梅毒性后胎盘状脉络膜视网膜炎前的早期视网膜表现。

Retinal Cases and Brief Reports Pub Date : 2025-05-01 DOI: 10.1097/ICB.0000000000001566

Michael Harrell, Alessandro Marchese, Lee M Jampol

引用次数: 0

NONSURGICAL CLOSURE OF FULL-THICKNESS MACULAR HOLE UNDER TOPICAL THERAPY IN TWO EYES WITH PATHOLOGIC MYOPIA. 两只病理性近视眼在局部治疗下以非手术方式闭合全厚黄斑孔。

Retinal Cases and Brief Reports Pub Date : 2025-05-01 DOI: 10.1097/ICB.0000000000001569

Mana Miyata, Takashi Ueta, Shuichiro Aoki, Kohdai Kitamoto, Keiko Azuma, Ryo Obata

{"title":"NONSURGICAL CLOSURE OF FULL-THICKNESS MACULAR HOLE UNDER TOPICAL THERAPY IN TWO EYES WITH PATHOLOGIC MYOPIA.","authors":"Mana Miyata, Takashi Ueta, Shuichiro Aoki, Kohdai Kitamoto, Keiko Azuma, Ryo Obata","doi":"10.1097/ICB.0000000000001569","DOIUrl":"10.1097/ICB.0000000000001569","url":null,"abstract":"Background/purpose: Nonsurgical closure of a full-thickness macular hole (FTMH) with eye drops has recently been reported, but there are few similar reports on cases with pathologic myopia.Methods: Case report.Results: (Case 1) The right eye of a 75-year-old female patient with an axial length of 28.83 mm had undergone anti-vascular endothelial growth factor treatment for choroidal neovascularization presented with FTMH. Topical betamethasone, bromfenac, and brinzolamide treatments were started, and the FTMH was closed with visual improvement (20/32 to 20/20) after 5 weeks. (Case 2) In the right eye of a 55-year-old male patient with an axial length of 30.81 mm and lacquer cracks, subretinal hyperreflective material and FTMH developed. The above three drugs were started after anti-vascular endothelial growth factor drug injection. After 16 weeks, the FTMH was closed with visual improvement (20/63 to 20/20).Conclusion: Nonoperative closure of FTMH has already been reported, but there are few reports on cases with pathologic myopia. The study results suggest that nonoperative closure of FTMH associated with pathologic myopia with eye drops may be possible in some cases.","PeriodicalId":53580,"journal":{"name":"Retinal Cases and Brief Reports","volume":" ","pages":"390-395"},"PeriodicalIF":0.0,"publicationDate":"2025-05-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140112188","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

RETINAL VASCULITIS IN A PATIENT WITH HANSEN DISEASE. 一名汉森氏病患者的视网膜血管炎。

Retinal Cases and Brief Reports Pub Date : 2025-05-01 DOI: 10.1097/ICB.0000000000001560

Shravan V Savant, Sarkis H Soukiasian, Richard F Spaide, Kendra A Klein-Mascia

{"title":"RETINAL VASCULITIS IN A PATIENT WITH HANSEN DISEASE.","authors":"Shravan V Savant, Sarkis H Soukiasian, Richard F Spaide, Kendra A Klein-Mascia","doi":"10.1097/ICB.0000000000001560","DOIUrl":"10.1097/ICB.0000000000001560","url":null,"abstract":"Purpose: Hansen disease is endemic in over 140 countries worldwide and a potentially blinding condition. The authors describe a case of retinal vasculitis in a patient with Hansen disease with concomitant positive antiphospholipid antibody serology, a potentially underreported complication in this setting.Methods: A 37-year-old Brazilian man systemically stable on triple therapy (clofazimine, rifampin, and dapsone) for Hansen disease presented for a comprehensive ophthalmic evaluation.Results: Dilated examination revealed diffuse peripheral intraretinal hemorrhages in his right eye. Fluorescein angiography showed peripheral nonperfusion, abnormal shunt vessels and leakage from the retinal veins in the right eye, and peripheral nonperfusion and vascular leakage in the fellow eye, consistent with vasculitis. Laboratory workup was notable for positive antiphospholipid antibodies (lupus anticoagulant, anticardiolipin immunoglobulin M (IgM), and anti-beta-2 glycoprotein 1 IgM) and normocytic anemia.Conclusion: As antiphospholipid antibodies are present in a large proportion of patients with Hansen disease, it is possible that retinal vasculitis may be more common than previously thought. The extent to which retinal vasculitis occurs in patients with Hansen disease remains uncertain and possibly underestimated due to the frequency of anterior segment scarring, which impedes retinal evaluation. Heightened surveillance for potential retinal vascular complications is warranted.","PeriodicalId":53580,"journal":{"name":"Retinal Cases and Brief Reports","volume":" ","pages":"323-327"},"PeriodicalIF":0.0,"publicationDate":"2025-05-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140050984","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

A RARE PRESENTATION OF NOCARDIA CHOROIDAL ABSCESS AFTER GLIOBLASTOMA SURGERY. 胶质母细胞瘤手术后出现脉络膜脓肿的罕见病例。

Retinal Cases and Brief Reports Pub Date : 2025-05-01 DOI: 10.1097/ICB.0000000000001573

Giacomo Visioli, Alessandro Beccia, Luca Lucchino, Davide Mastromarino, Maria Pia Pirraglia

{"title":"A RARE PRESENTATION OF NOCARDIA CHOROIDAL ABSCESS AFTER GLIOBLASTOMA SURGERY.","authors":"Giacomo Visioli, Alessandro Beccia, Luca Lucchino, Davide Mastromarino, Maria Pia Pirraglia","doi":"10.1097/ICB.0000000000001573","DOIUrl":"10.1097/ICB.0000000000001573","url":null,"abstract":"Purpose: The aim of this study was to report the natural history of a rare ocular manifestation of endogenous Nocardia farcinica infection in a patient with compromised immune system, with involvement observed in both the anterior and posterior segments of the eye.Methods and results: Given the patient's limited mobility, a handheld fundus camera was utilized for bedside anterior segment and ocular fundus examinations. The findings included visual acuity of hand motion, posterior synechiae, vitreal opacity, and a large choroidal abscess. The authors monitored the lesion's progression through a series of follow-ups. Despite not employing intravitreal drug therapy, they noted a significant reduction in the lesion's size until the patient's overall health deteriorated.Conclusion: This case contributes valuable information to our understanding of the natural history of a rare condition like Nocardia endophthalmitis. The authors highlighted the usefulness of a handheld fundus camera in aiding infectious disease specialists in assessing the immediate response to systemic treatment.","PeriodicalId":53580,"journal":{"name":"Retinal Cases and Brief Reports","volume":" ","pages":"338-341"},"PeriodicalIF":0.0,"publicationDate":"2025-05-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140061234","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

THE PERIPAPILLARY RETINA: A COMMON JUNCTURE IN STARGARDT DISEASE AND IDIOPATHIC INTRACRANIAL HYPERTENSION. 视网膜毛周--Stargardt 病和特发性颅内高压症的共同关口。

Retinal Cases and Brief Reports Pub Date : 2025-05-01 DOI: 10.1097/ICB.0000000000001561

Jin Kyun Oh, Meital Ben Dov, Stephen H Tsang, Jeffrey G Odel

{"title":"THE PERIPAPILLARY RETINA: A COMMON JUNCTURE IN STARGARDT DISEASE AND IDIOPATHIC INTRACRANIAL HYPERTENSION.","authors":"Jin Kyun Oh, Meital Ben Dov, Stephen H Tsang, Jeffrey G Odel","doi":"10.1097/ICB.0000000000001561","DOIUrl":"10.1097/ICB.0000000000001561","url":null,"abstract":"Purpose: The objective of this study was to present the multimodal imaging and functional examination findings in a case of combined Stargardt disease and idiopathic intracranial hypertension.Methods: The patient was evaluated with multimodal imaging including color fundus photography, short-wavelength autofluorescence, spectral domain optical coherence tomography, and functional testing such as Humphrey visual fields and full-field electroretinogram.Results: A 35-year-old woman was referred for evaluation of bilateral transient visual obscurations over the course of 2 months. Optic disc edema was observed in both eyes and a bull's-eye maculopathy with pisciform flecks. Magnetic resonance imaging and subsequent lumbar puncture confirmed a diagnosis of idiopathic intracranial hypertension. Fundus autofluorescence demonstrated hyperautofluorescent flecks surrounding both the macula and the disc. Genetic testing and full-field electroretinogram confirmed a diagnosis of Stargardt disease. Notably, the peripapillary retina was not spared as is frequently seen in Stargardt disease, possibly due to the impact of disc edema in the area. The patient was treated with increasing doses of acetazolamide, and familial testing for Stargardt disease was recommended.Conclusion: Both Stargardt disease and idiopathic intracranial hypertension are separately rare diseases with common anatomic intersection at the peripapillary retina. Stargardt disease typically spares the peripapillary retina; however, the presented case shows some evidence of peripapillary involvement. This finding suggests some relationship between disc edema due to idiopathic intracranial hypertension and the natural history of Stargardt disease.","PeriodicalId":53580,"journal":{"name":"Retinal Cases and Brief Reports","volume":" ","pages":"372-375"},"PeriodicalIF":0.0,"publicationDate":"2025-05-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11366037/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140013747","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

SCLERAL FIXATION OF THE SMALLER-INCISION NEW-GENERATION IMPLANTABLE MINIATURE TELESCOPE USING GORE-TEX SUTURE. 使用 GoreTex 缝合线固定小切口新一代植入式微型望远镜（SING IMT ™）的巩膜。

Retinal Cases and Brief Reports Pub Date : 2025-05-01 DOI: 10.1097/ICB.0000000000001572

Alfonso Savastano, Leonardo Andrea Sammarco, Giuseppe Francione, Paola Sasso, Stanislao Rizzo

{"title":"SCLERAL FIXATION OF THE SMALLER-INCISION NEW-GENERATION IMPLANTABLE MINIATURE TELESCOPE USING GORE-TEX SUTURE.","authors":"Alfonso Savastano, Leonardo Andrea Sammarco, Giuseppe Francione, Paola Sasso, Stanislao Rizzo","doi":"10.1097/ICB.0000000000001572","DOIUrl":"10.1097/ICB.0000000000001572","url":null,"abstract":"Purpose: In this case report, the authors describe a surgical technique for scleral fixation of the smaller-incision new-generation implantable miniature telescope (SING-IMT). Using this surgical technique, the patient's eye that undergoes surgery for the SING-IMT could still have a safe SING IMT implant despite the anatomical conditions of the capsular bag or in cases of intraoperative complications.Methods: The surgery was performed at Policlinico A. Gemelli, Rome, Italy. The patient's eye underwent a first surgery for an artificial intraocular lens explant and SING-IMT implant at the same time. The authors observed SING IMT dislocation into the vitreous chamber 90 days after surgery. Therefore, they carried out a 23-gauge vitrectomy, and after SING IMT recovery from the vitreous chamber, they fixed one of its haptic to the sclera using an 8.0 Gore-Tex suture.Conclusion: Scleral fixation of SING-IMT haptics might be useful in eyes with dislocated or not stable SING IMT. The authors believe that reporting our experience can help surgeons fix SING IMT in complicated cases where a capsular bag rupture or disinsertion (like our case) can cause SING IMT decentration or worse its drop into the vitreous chamber. They speculate that the Gore-Tex suture could assure firm fixation of the SING IMT and could reduce the risk of recurrent dislocations.","PeriodicalId":53580,"journal":{"name":"Retinal Cases and Brief Reports","volume":" ","pages":"410-412"},"PeriodicalIF":0.0,"publicationDate":"2025-05-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140307806","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

RAHNELLA AQUATILIS ENDOPHTHALMITIS AFTER INTRAVITREAL INJECTION IN AN IMMUNOCOMPETENT PATIENT. 一名免疫功能正常的患者在接受玻璃体内注射后发生水蛭眼内炎

Retinal Cases and Brief Reports Pub Date : 2025-05-01 DOI: 10.1097/ICB.0000000000001567

Parker J Williams, Gilbert Xue, Bing X Ross, Erika White, Lisa Shammas, Pradeepa Yoganathan, Christopher Chapman, Xihui Lin

{"title":"RAHNELLA AQUATILIS ENDOPHTHALMITIS AFTER INTRAVITREAL INJECTION IN AN IMMUNOCOMPETENT PATIENT.","authors":"Parker J Williams, Gilbert Xue, Bing X Ross, Erika White, Lisa Shammas, Pradeepa Yoganathan, Christopher Chapman, Xihui Lin","doi":"10.1097/ICB.0000000000001567","DOIUrl":"10.1097/ICB.0000000000001567","url":null,"abstract":"Purpose: The objective of this study was to present a novel case of exogenous Rahnella aquatilis endophthalmitis following an intravitreal injection.Methods: This was a case report.Results: A 74-year-old man presented with acute progressive vision loss and pain in the left eye, 5 days after an intravitreal injection for diabetic macular edema. The patient was diagnosed with exogenous endophthalmitis and empirically treated with intravitreal injections of vancomycin and ceftazidime as well as topical and oral ciprofloxacin. At follow-up 2 days later, the patient was treated with preoperative povidone-iodine, followed by prompt vitrectomy with additional vancomycin and ceftazidime due to pharmacy sterile hood issues that delayed antibiotic availability. Microbiological cultures and two mass spectrometry identification tests confirmed the diagnosis of exogenous R. aquatilis endophthalmitis. Despite the presence of scattered retinal hemorrhagic infarcts involving the macula and subsequent full-thickness atrophic macular holes seen in follow-up, the patient achieved a favorable anatomical and functional outcome of best corrected visual acuity 20/80 at 1-year follow-up.Conclusion: This case highlights the occurrence of exogenous R. aquatilis endophthalmitis following an intravitreal injection for diabetic macular edema. Prompt diagnosis and treatment produced a favorable outcome relative to other typical gram-negative Enterobacteriaceae organisms.","PeriodicalId":53580,"journal":{"name":"Retinal Cases and Brief Reports","volume":" ","pages":"311-314"},"PeriodicalIF":0.0,"publicationDate":"2025-05-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140029587","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

A NOVEL RLBP1 GENE MUTATION ASSOCIATED WITH RETINAL FLECKS. 一种与斑点视网膜综合征相关的新型 RLBP1 基因突变。

Retinal Cases and Brief Reports Pub Date : 2025-05-01 DOI: 10.1097/ICB.0000000000001574

Mohamad Issa, Georges Sukkarieh, Sebastien Bruneau, Ramin Tadayoni

引用次数: 0

A CASE OF ALSTRÖM SYNDROME WITH A NOVEL VARIANT IN ALMS1 GENE PRESENTING WITH CONE ROD DYSTROPHY AS FIRST FINDING. 一例alström综合征病例，首次发现其患有锥杆营养不良症，并伴有alström1基因的新型变异。

Retinal Cases and Brief Reports Pub Date : 2025-05-01 DOI: 10.1097/ICB.0000000000001578

Busra Yen, Mukaddes Damla Ciftci, Filiz Afrashi, Huseyin Onay, Damla Goksen

{"title":"A CASE OF ALSTRÖM SYNDROME WITH A NOVEL VARIANT IN ALMS1 GENE PRESENTING WITH CONE ROD DYSTROPHY AS FIRST FINDING.","authors":"Busra Yen, Mukaddes Damla Ciftci, Filiz Afrashi, Huseyin Onay, Damla Goksen","doi":"10.1097/ICB.0000000000001578","DOIUrl":"10.1097/ICB.0000000000001578","url":null,"abstract":"Purpose: Alström syndrome is a rare autosomal recessive monogenic ciliopathy, which is caused by a mutation of the Alström syndrome 1 gene. It is a multisystemic disorder characterized by insulin resistance, childhood obesity, cardiomyopathy, progressive hepatic and renal failure, sensorineural hearing loss, and retinal degeneration. In this study, we aimed to report a novel variant in Alström syndrome 1 gene causing Alström syndrome in a patient presenting with visual impairment.Methods: This was a case report.Results: A 10-year-old male patient presented with photophobia and visual impairment in both eyes. Anterior and posterior segment examinations were unremarkable bilaterally. Optical coherence tomography showed attenuated ellipsoid zone. Electroretinography revealed diminished cone and rod responses consistent with cone-rod dystrophy. Genetic testing demonstrated a novel homozygous variant in Alström syndrome 1 (NM_015120.4) gene. The patient also was found to have early stage dilated cardiomyopathy through systemic evaluation after the diagnosis of Alström syndrome.Conclusion: Cone-rod dystrophy in pediatric population is relatively rare condition that can be associated with syndromic ciliopathies. The authors presented a case of Alström syndrome with a novel variant in Alström syndrome 1 gene based on ophthalmic findings. Ophthalmologists play an important role in the diagnosis of this syndrome and early detection of systemic manifestations.","PeriodicalId":53580,"journal":{"name":"Retinal Cases and Brief Reports","volume":" ","pages":"413-417"},"PeriodicalIF":0.0,"publicationDate":"2025-05-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140871780","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0