{"title":"CARTRIDGE-ASSISTED SCLERAL FIXATION OF A FOUR-LOOPED HAPTICS INTRAOCULAR LENS USING LOOPED SUTURES.","authors":"Chengye Tan, Qingru Wang, Yanqiu Liu, Tianhua Xie, Miao Zhuang, Yong Yao","doi":"10.1097/ICB.0000000000001847","DOIUrl":"10.1097/ICB.0000000000001847","url":null,"abstract":"<p><strong>Purpose: </strong>To describe a modified scleral fixation technique for a four-haptic foldable intraocular lens using 10-0 looped polypropylene sutures, aimed at reducing suture exposure risks and enhancing centration stability in eyes with inadequate capsular support.</p><p><strong>Methods: </strong>This retrospective interventional study included nine eyes of nine patients, who underwent modified scleral fixation of a four-haptic foldable intraocular lens between January 2023 and January 2024.</p><p><strong>Results: </strong>Over a mean follow-up period of 10.89 months, postoperative logarithm of the minimum angle of resolution best-corrected visual acuity improved significantly (20/43 vs. 20/130 preoperatively). The mean intraocular lens tilt was 0.27 ± 0.09 µ m, with acceptable endothelial cell loss (9.96%). No intraoperative or postoperative complications were observed.</p><p><strong>Conclusion: </strong>This technique performed through a small incision, achieves reliable intraocular lens positioning and visual improvement via four-point fixation while effectively eliminating suture-related complications.</p>","PeriodicalId":53580,"journal":{"name":"Retinal Cases and Brief Reports","volume":" ","pages":"466-470"},"PeriodicalIF":0.0,"publicationDate":"2026-05-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145688727","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Elizabeth Y Wei, Marko M Popovic, Panos G Christakis
{"title":"SYSTEMIC LYMPHOMA MASQUERADING AS BIRDSHOT CHORIORETINOPATHY.","authors":"Elizabeth Y Wei, Marko M Popovic, Panos G Christakis","doi":"10.1097/ICB.0000000000001743","DOIUrl":"10.1097/ICB.0000000000001743","url":null,"abstract":"<p><strong>Purpose: </strong>To report a rare case of systemic lymphoma causing a birdshot-like chorioretinopathy in a histocompatibility leukocyte antigen-A29-negative patient.</p><p><strong>Methods: </strong>A 58-year-old man presented with a 1-year history of blurry vision and intermittent floaters. He had evidence of bilateral choroidal birdshot-like lesions that appeared atrophic without any vitritis. He had a history of low-grade B-cell lymphoma and chronic myeloid leukemia, both of which were diagnosed >10 years before presentation and treated with chemotherapy.</p><p><strong>Results: </strong>The differential diagnosis of these birdshot-like lesions included autoimmune, neoplastic, and infectious etiologies. Work-up revealed a negative histocompatibility leukocyte antigen-A29 and negative results for syphilis and tuberculosis. Magnetic resonance imaging revealed enhancement of the trigeminal and oculomotor nerve cisternal segments but no overt evidence of malignancy. Full-field electroretinogram and multifocal electroretinogram tests were within normal limits. Serial follow-up clinical examinations, retinal imaging, full-field electroretinogram, and multifocal electroretinogram demonstrated no disease progression. Two years after his initial consultation, he developed a paraspinal mass that was biopsied and found to be diffuse large B-cell lymphoma and was treated with chemotherapy.</p><p><strong>Conclusion: </strong>Clinicians should consider birdshot-like chorioretinopathy masquerade syndromes in patients who present with birdshot-like choroidal lesions with negative histocompatibility leukocyte antigen-A29, a history of lymphoma, or atypical characteristics. In this case, the authors suspect the patient's past low-grade B-cell lymphoma, and chemotherapy resulted in the chronic choroidal findings. It is unclear whether choroidal involvement predisposes a patient to high-grade transformation to diffuse large B-cell lymphoma. His ocular findings remained inactive throughout the treatment of his diffuse large B-cell lymphoma.</p>","PeriodicalId":53580,"journal":{"name":"Retinal Cases and Brief Reports","volume":" ","pages":"360-363"},"PeriodicalIF":0.0,"publicationDate":"2026-05-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143528005","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Fernanda Galante Dourado, Daniel Queiroz Omote, Paula Dandara Correia de Pinho, Sergio Luis Gianotti Pimentel
{"title":"RETINAL DYSTROPHY AS AN UNUSUAL MANIFESTATION OF TRICHOTHIODYSTROPHY.","authors":"Fernanda Galante Dourado, Daniel Queiroz Omote, Paula Dandara Correia de Pinho, Sergio Luis Gianotti Pimentel","doi":"10.1097/ICB.0000000000001756","DOIUrl":"10.1097/ICB.0000000000001756","url":null,"abstract":"<p><strong>Purpose: </strong>Describe a case of retinal dystrophy as an ophthalmologic manifestation of trichothiodystrophy in a young patient.</p><p><strong>Methods: </strong>Multimodal retinal imaging evaluation was performed, with color fundus photograph, fundus autofluorescence, fluorescein angiography, optical coherence tomography, and electroretinogram. Genetic testing confirmed the systemic diagnosis.</p><p><strong>Results: </strong>Genetic testing confirmed the diagnosis of trichothiodystrophy, and retinal dystrophy was considered a rare manifestation of the systemic disease.</p><p><strong>Conclusion: </strong>Ophthalmologic manifestations in trichothiodystrophy are variable, with cataracts and refractive errors being the most reported, although our case had a retinal dystrophy. Retinal degeneration is not typically considered a hallmark of trichothiodystrophy but should be considered as a rare ophthalmologic manifestation in this syndromic disease.</p>","PeriodicalId":53580,"journal":{"name":"Retinal Cases and Brief Reports","volume":" ","pages":"410-413"},"PeriodicalIF":0.0,"publicationDate":"2026-05-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143784509","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Michael Mann, Da Meng, Renee Liu, Henry W Zhou, Yandong Bian, Joseph J Raevis, Lucia Sobrin, Michael Leukam
{"title":"CANCER-ASSOCIATED RETINOPATHY AFTER CHIMERIC ANTIGEN RECEPTOR T-CELL THERAPY.","authors":"Michael Mann, Da Meng, Renee Liu, Henry W Zhou, Yandong Bian, Joseph J Raevis, Lucia Sobrin, Michael Leukam","doi":"10.1097/ICB.0000000000001737","DOIUrl":"10.1097/ICB.0000000000001737","url":null,"abstract":"<p><strong>Purpose: </strong>To describe a case of cancer-associated retinopathy (CAR) after chimeric antigen receptor T (CART)-cell therapy.</p><p><strong>Methods: </strong>Retrospective case report.</p><p><strong>Results: </strong>A 71-year-old man with follicular lymphoma refractory to multiple chemotherapies underwent CART-cell therapy. Two weeks after CART initiation, he presented with rapid-onset decreased peripheral vision in both eyes. Fluorescein angiography showed attenuation of peripheral vessel filling, and optical coherence tomography showed loss of ellipsoid zone with foveal sparing. Electroretinography revealed nondetectable rod responses and severely prolonged and diminished cone responses. Antiretinal antibody testing showed positive antienolase and antiheat shock protein 60 antibodies on Western blot with strong staining of the outer segments on immunohistochemistry. The patient was diagnosed with CAR and is currently on monthly IV immunoglobulin (IVIg) with stable central visual acuity.</p><p><strong>Conclusion: </strong>This patient developed CAR immediately after receiving CART-cell therapy, which depletes B cells. This suggests that CAR pathophysiology may not be purely autoantibody mediated as typically believed.</p>","PeriodicalId":53580,"journal":{"name":"Retinal Cases and Brief Reports","volume":"20 3","pages":"355-359"},"PeriodicalIF":0.0,"publicationDate":"2026-05-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147823413","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Melissa M Medina Melo, Laura Quintero Arciniegas, Santiago Morales Orozco
{"title":"IN VIVO SURGICAL APPROACH OF SUBRETINAL CYSTICERCOSIS: A CASE REPORT.","authors":"Melissa M Medina Melo, Laura Quintero Arciniegas, Santiago Morales Orozco","doi":"10.1097/ICB.0000000000001748","DOIUrl":"10.1097/ICB.0000000000001748","url":null,"abstract":"<p><strong>Purpose: </strong>To report the clinical and imaging findings of a patient with right eye progressive vision loss, in whom ocular neurocysticercosis was diagnosed. The patient underwent vitreoretinal surgery with previous antihelmintic treatment, resulting in a successful extraction of the subretinal cyst.</p><p><strong>Methods: </strong>A patient with subretinal neurocysticercosis underwent a combination of ophthalmic examination, fundus photography, ocular ultrasonography, brain MRI, and surgery.</p><p><strong>Results: </strong>A 57-year-old woman from La Guajira, Colombia, presented with a 2-year history of unilateral subretinal neurocysticercosis and an overlying exudative inferior retinal detachment with multiple areas of retinal pigment epithelium atrophy. Different methods of surgery were contemplated to achieve a favorable outcome, until deciding on a microincision vitrectomy surgery.</p><p><strong>Conclusion: </strong>An \"in vivo\" minimally invasive pars plana approach should be considered, given it has proven to be successful in removing intraocular cysts with no postoperative inflammatory response, preserving anatomic and functional integrity.</p>","PeriodicalId":53580,"journal":{"name":"Retinal Cases and Brief Reports","volume":" ","pages":"447-451"},"PeriodicalIF":0.0,"publicationDate":"2026-05-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC13166057/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143607270","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"CHOROIDAL SYNPHLEBIA IN A PATIENT WITH CENTRAL SEROUS CHORIORETINOPATHY.","authors":"Amirreza Naderi, Richard F Spaide","doi":"10.1097/ICB.0000000000001728","DOIUrl":"10.1097/ICB.0000000000001728","url":null,"abstract":"<p><strong>Purpose: </strong>The purpose of this study was to describe the choroidal vascular abnormality of conjoined choroidal vessels, synphlebia, in a patient with central serous chorioretinopathy.</p><p><strong>Methods: </strong>A patient initially referred for pigmentary retinal dystrophy later developed central serous retinopathy and underwent a comprehensive examination with multimodal imaging.</p><p><strong>Results: </strong>A 30-year-old man had an undiagnosed pigmentary retinopathy, and nyctalopia was found to have a dehydrodolichyl diphosphate synthase mutation, confirming a retinitis pigmentosa diagnosis. A year later, he presented with bilateral central serous chorioretinopathy. During the venous phase of indocyanine green angiography, individual vessels could not be differentiated in the posterior pole. Swept source optical coherence tomography revealed an abnormally thick choroid with enormous vascular channels that did not appear to have separation into individual tubular structures. These abnormal vessels nearly occupied the entire thickness of the choroid in the macular region. There was little sign of any intermediate-sized choroidal vessels in the posterior pole. A review of other patients with dehydrodolichyl diphosphate synthase mutation showed no similar choroidal vascular changes.</p><p><strong>Conclusion: </strong>Large, conjoined veins, which we termed synphlebia, were seen in an eye with central serous chorioretinopathy. Loading of the choriocapillaris from these enlarged vascular channels may have contributed to hyperpermeability and formation of serous fluid. Observation of this choroidal vascular pattern suggests that a central serous chorioretinopathy phenotype may develop through more than one pathway.</p>","PeriodicalId":53580,"journal":{"name":"Retinal Cases and Brief Reports","volume":" ","pages":"289-293"},"PeriodicalIF":0.0,"publicationDate":"2026-05-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143392573","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"OCCULT INVASIVE FUNGAL SINUSITIS IN A PATIENT WITH ACUTE VOGT-KOYANAGI-HARADA DISEASE.","authors":"Emily C Davis, Akshay S Thomas","doi":"10.1097/ICB.0000000000001754","DOIUrl":"10.1097/ICB.0000000000001754","url":null,"abstract":"<p><strong>Purpose: </strong>We present a case of the development of invasive fungal sinusitis in a patient with acute Vogt-Koyanagi-Harada Disease (VKHD).</p><p><strong>Methods: </strong>Observational case report.</p><p><strong>Results: </strong>A 39-year-old African American woman presented with acute vision loss in both eyes and reported pain around her left eye. Examination revealed a bilateral posterior uveitis with significant macular edema and subretinal fluid in both eyes. Systemic and ocular findings were consistent with complete VKHD and the patient was put on oral glucocorticoids. At follow-up 2 weeks later, blood sugars were found to be severely elevated, and the patient was hospitalized. During hospitalization, the patient was taken off steroids. At follow-up, the uveitis appeared quiescent, but vision was still poor in the left eye. The patient reported a continued sense of pressure and now numbness around the left eye. An MRI revealed occult invasive fungal sinusitis and the patient was hospitalized for treatment. The patient recovered after surgery for debridement of the sinuses and several weeks of treatment with amphotericin B. At the most recent follow-up, 18 months after the initial visit, the patient's VA was 20/20 OD and 20/50 with eccentric viewing OS.</p><p><strong>Conclusion: </strong>Many forms of uveitis such as acute VKHD require use of oral glucocorticoids. However, proper use of glucocorticoids involves patient counseling on potential side effects and the prescribing physician to identify potential life-threatening complications. In this case, failure to identify either the severely elevated blood sugars or occult fungal sinusitis could have resulted in significant patient morbidity or even mortality.</p>","PeriodicalId":53580,"journal":{"name":"Retinal Cases and Brief Reports","volume":" ","pages":"457-461"},"PeriodicalIF":0.0,"publicationDate":"2026-05-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143774878","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Robert D Nguyen, Martin Dionson, Emmanuel Agu, John A Gonzales
{"title":"A NOVEL CASE STUDY OF UNILATERAL SEROUS RETINAL DETACHMENT IN A GLAUCOMA PATIENT WITH NEPHROTIC SYNDROME.","authors":"Robert D Nguyen, Martin Dionson, Emmanuel Agu, John A Gonzales","doi":"10.1097/ICB.0000000000001755","DOIUrl":"10.1097/ICB.0000000000001755","url":null,"abstract":"<p><strong>Purpose: </strong>To present a case of a unilateral serous retinal detachment in a patient with nephrotic syndrome after Ahmed valve implantation.</p><p><strong>Methods: </strong>Retrospective descriptive case report.</p><p><strong>Results: </strong>A 63-year-old man with a history of Ahmed valve implantation, diabetes, and hypertension presented with progressive corneal edema and decreased vison who developed a serous retinal detachment in the right eye. There was no view of the fundus because of the massive retinal detachment. B-scan ultrasonography revealed a serous retinal detachment with mild choroidal thickening. Along with the development of anasarca, laboratory testing revealed significant proteinuria and hypoalbuminemia, consistent with nephrotic syndrome. Fluid restriction and treatment with diuretics and antihypertensives resulted in rapid resolution of the serous retinal detachment.</p><p><strong>Conclusion: </strong>Although nephrotic syndrome can cause central serous retinal detachment, the presentation is almost always bilateral. A unilateral serous retinal detachment presentation can occur in patients with risk factors such as a history of Ahmed valve implantation and conditions that alter intravascular fluid hydrostatic and oncotic pressures. Prompt recognition of nephrotic syndrome in patients with kidney disease who develop serous retinal detachment is critical. Early treatment with diuretic therapy can significantly resolve ocular complications and potentially improve patient outcomes.</p>","PeriodicalId":53580,"journal":{"name":"Retinal Cases and Brief Reports","volume":" ","pages":"401-405"},"PeriodicalIF":0.0,"publicationDate":"2026-05-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143784500","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Federica Mirabella, Nicola C D'Onofrio, Stanislao Rizzo
{"title":"A HEAD-TO-HEAD COMPARISON OF EFFICIENCY IN TWO MODERN VITREORETINAL SURGERY PLATFORMS.","authors":"Federica Mirabella, Nicola C D'Onofrio, Stanislao Rizzo","doi":"10.1097/ICB.0000000000001878","DOIUrl":"10.1097/ICB.0000000000001878","url":null,"abstract":"","PeriodicalId":53580,"journal":{"name":"Retinal Cases and Brief Reports","volume":" ","pages":"471-478"},"PeriodicalIF":0.0,"publicationDate":"2026-05-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"146167757","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Prabu Baskaran, Savithri Palanivel, Yeshwanth Kumar
{"title":"ACTIVE EXTERNAL DRAINAGE OF SUBRETINAL FLUID WITHOUT VITRECTOMY TO TREAT ADVANCED COATS DISEASE WITH EXUDATIVE RETINAL DETACHMENT-A CASE REPORT AND LITERATURE REVIEW.","authors":"Prabu Baskaran, Savithri Palanivel, Yeshwanth Kumar","doi":"10.1097/ICB.0000000000001745","DOIUrl":"10.1097/ICB.0000000000001745","url":null,"abstract":"<p><strong>Purpose: </strong>The purpose of this study was to illustrate the successful management of advanced Coats disease with exudative retinal detachment with posterior lens touch in a 3-year-old young boy using the subretinal drainage technique using an extrusion cannula.</p><p><strong>Methods: </strong>Under general anesthesia, external drainage of subretinal fluid was performed using an active extrusion cannula. Concurrent cryotherapy and endolaser treatment were administered, with cytological analysis of subretinal fluid to exclude retinoblastoma.</p><p><strong>Results: </strong>The retina achieved near-complete reattachment on the first postoperative day and maintained stability during the 6-month follow-up period.</p><p><strong>Conclusion: </strong>Active extrusion cannula-based subretinal drainage technique might be helpful to achieve quicker reattachment of the retina in advanced Coats disease with massive exudative retinal detachment.</p>","PeriodicalId":53580,"journal":{"name":"Retinal Cases and Brief Reports","volume":" ","pages":"414-418"},"PeriodicalIF":0.0,"publicationDate":"2026-05-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143607268","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}