Retinal Cases and Brief Reports最新文献_第9页

Central retinal artery and Common Carotid artery occlusions following COVID-19 infection: A case report. COVID-19感染后视网膜中央动脉和颈总动脉闭塞：病例报告。

Retinal Cases and Brief Reports Pub Date : 2024-08-19 DOI: 10.1097/ICB.0000000000001651

Mohamed Eldakkak, Dimitrios Kalogeropoulos, Andrew J Lotery

引用次数: 0

Long Term Follow Up of a Family with A3243G Mitochondrial Syndrome. 一个 A3243G 线粒体综合征家庭的长期随访。

Retinal Cases and Brief Reports Pub Date : 2024-08-14 DOI: 10.1097/ICB.0000000000001647

Alessandro Feo, Claudia Fossataro, Néda Abraham, Shilo Voichanski, Jack D Lemon, David Sarraf

{"title":"Long Term Follow Up of a Family with A3243G Mitochondrial Syndrome.","authors":"Alessandro Feo, Claudia Fossataro, Néda Abraham, Shilo Voichanski, Jack D Lemon, David Sarraf","doi":"10.1097/ICB.0000000000001647","DOIUrl":"https://doi.org/10.1097/ICB.0000000000001647","url":null,"abstract":"Purpose: To describe the clinical and multimodal imaging (MMI) features of a family (proband, sister and mother) with A3243G mitochondrial retinopathy and long-term follow up.Methods: Medical and imaging records were retrospectively evaluated. Multimodal imaging included ultra-widefield color fundus photography, fundus autofluorescence, and spectral-domain optical coherence tomography. Long-term MMI follow up ranged from 6 to 15 years and was available for each member.Results: The proband (Case 1) exhibited rapidly progressive bilateral macular atrophy, corneal endothelial polymegathism, and an A3243G mutation in the mitochondrial DNA. The proband also endorsed a history of early-onset myocardial infarction (MI) ten years prior at the age of 42. The proband's sister (Case 2) only exhibited unilateral focal macular atrophy but admitted to a history of severe multiorgan systemic disease, including multiple sclerosis and major depression disorder. The proband's mother (Case 3), the only one with diabetes mellitus and hearing loss, originally presented with branch retinal vein occlusion in the right eye and pattern dystrophy in the left eye which evolved to geographic atrophy, OD > OS, 15 years later.Conclusion: A3243G mitochondrial syndrome can exhibit heterogenous ocular and systemic features, even within members of the same family. The development of the characteristic maculopathy with early-onset MI warrants genetic testing. Early cardiac and systemic screening may be recommended in individuals with characteristic retinal findings and genetic confirmation.","PeriodicalId":53580,"journal":{"name":"Retinal Cases and Brief Reports","volume":" ","pages":""},"PeriodicalIF":0.0,"publicationDate":"2024-08-14","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141992498","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Serous Choroidal Detachment Associated with Suspected Contralateral Cavernous Sinus Thrombosis. 疑似对侧海绵窦血栓形成导致的浆液性脉络膜脱离

Retinal Cases and Brief Reports Pub Date : 2024-08-09 DOI: 10.1097/ICB.0000000000001650

Dominic M Choo, Arjun G Merchant, Angeline L Wang

{"title":"Serous Choroidal Detachment Associated with Suspected Contralateral Cavernous Sinus Thrombosis.","authors":"Dominic M Choo, Arjun G Merchant, Angeline L Wang","doi":"10.1097/ICB.0000000000001650","DOIUrl":"https://doi.org/10.1097/ICB.0000000000001650","url":null,"abstract":"Purpose: To describe a case of choroidal detachment (CD) secondary to cavernous sinus thrombosis (CST).Methods: Case report.Results: A 73-year-old male with a history of primary open angle glaucoma and pseudophakia presented with retrobulbar pain, blurred vision, and diplopia of the right eye. Exam revealed severe non-hemorrhagic bullous chemosis, tortuous retinal vessels, and elevated intraocular pressure (IOP) in the right eye. Although computed tomography venography findings initially raised suspicion of a carotid-cavernous fistula (CCF), the diagnostic angiogram showed no such evidence, instead raising concern for cavernous sinus thrombosis (CST). Dilated fundus exam and MRI were notable for multiple serous choroidal detachments in the right eye, which resolved with systemic management of CST and topical steroids.Conclusion: The possibility of choroidal detachment during the clinical course of a CST should be recognized. CST may be related to impaired venous drainage that forces transudate into perivascular spaces and results in choroidal effusion.","PeriodicalId":53580,"journal":{"name":"Retinal Cases and Brief Reports","volume":" ","pages":""},"PeriodicalIF":0.0,"publicationDate":"2024-08-09","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141910177","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Paenibacillus lautus: A new foe in endogenous endophthalmitis. 猪链球菌：内源性眼内炎的新敌人。

Retinal Cases and Brief Reports Pub Date : 2024-08-06 DOI: 10.1097/ICB.0000000000001636

Aditi Joshi, Chetan Rao, Parthopratim Dutta Majumder, A R Anand

{"title":"Paenibacillus lautus: A new foe in endogenous endophthalmitis.","authors":"Aditi Joshi, Chetan Rao, Parthopratim Dutta Majumder, A R Anand","doi":"10.1097/ICB.0000000000001636","DOIUrl":"https://doi.org/10.1097/ICB.0000000000001636","url":null,"abstract":"Purpose: To discuss the diagnosis and management of a rare case of endogenous endophthalmitis (EE) caused by Paenibacillus lautus mimicking granulomatous uveitis in a child, highlighting the use of 16S rRNA gene amplicon sequencing as an accurate method to identify rare pathogens.Method: A retrospective chart review of the clinical presentation, microbiologic workup-including microscopy, culture, antibiotic susceptibility, and polymerase chain reaction for pathogen DNA of clinical samples-and the clinical management of the case were recorded.Result: A 13-year-old boy presented with decreased vision in the right eye for one month. On examination, he had uveitis with hypopyon and complicated cataract. The case underwent an anterior chamber tap followed by vitrectomy and lensectomy. The culture of the vitreous aspirate grew Gram-variable bacilli that could not be identified by conventional microbiological techniques. However, PCR-based sequencing of the 16S rRNA gene was performed, and the bacterium was identified as P. lautus. The patient subsequently developed rhegmatogenous retinal detachment, for which he underwent endo laser photocoagulation and oil tamponade. Four months later, silicone oil was removed, and an intraocular lens was implanted. At six weeks follow-up, the retina remained well attached, and intraocular pressure was maintained.Conclusion: P. lautus can cause EE and mimic granulomatous uveitis. Techniques such as 16S rRNA gene sequencing can significantly facilitate aetiological diagnosis in cases where conventional methods fail.","PeriodicalId":53580,"journal":{"name":"Retinal Cases and Brief Reports","volume":" ","pages":""},"PeriodicalIF":0.0,"publicationDate":"2024-08-06","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141910176","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Management of Perifoveal Exudative Vascular Anomalous Complex. 眼底渗出性血管异常复合体的处理方法

Retinal Cases and Brief Reports Pub Date : 2024-08-05 DOI: 10.1097/ICB.0000000000001649

Maria Cristina Savastano, Claudia Fossataro, Gianni Gravina, Francesca Coccimiglio, Clara Rizzo, Stanislao Rizzo

{"title":"Management of Perifoveal Exudative Vascular Anomalous Complex.","authors":"Maria Cristina Savastano, Claudia Fossataro, Gianni Gravina, Francesca Coccimiglio, Clara Rizzo, Stanislao Rizzo","doi":"10.1097/ICB.0000000000001649","DOIUrl":"https://doi.org/10.1097/ICB.0000000000001649","url":null,"abstract":"Purpose: To report a case of a patient with perifoveal exudative vascular anomalous complex (PEVAC) and to analyze morphological and vascular changes by OCT and OCTA before and after treatment.Materials and methods: In this case we reported a case which received multiple treatment for unresponsive effect to Repeated Aflibercept intravitreal injections, subthreshold micropulse laser therapy (SMPL) duty cycle 5%. At last the focal fully dose yellow laser was performed.Results: A 57-year-old male patient presented with best corrected visual acuity (BCVA) of 20/50 in his right eye (RE) The fundoscopic evaluation, structural optical coherence tomography (OCT) and OCT angiography (OCTA) deposed for a diagnosis of PEVAC. The patient underwent three Aflibercept intravitreal injections in the RE. Since no changes were detected, we opted for multiple sessions of yellow subthreshold micropulse laser therapy (SMPL) duty cycle 5%, however no signs of regression were registered. Only after a fully dose yellow laser, signs of edema regression were observed. Stuctural OCT B-scan showed complete restitutio of retinal profile, in absence of any intraretinal or subretinal fluid and PEVAC lesion, while the OCTA showed a slight flow deficit at the previous lesion site.Conclusions: and Importance: The PEVAC treatment is still unknown. In our experience, we reported a case of multiple treatments for unresponsive effect to: Aflibercept intravitreal injections, subthreshold micropulse laser therapy (SMPL) duty cycle 5%. At list the focal fully dose yellow laser was the only effective in our patient. We proposed our management to share the heterogeneous response at PEVAC entity.","PeriodicalId":53580,"journal":{"name":"Retinal Cases and Brief Reports","volume":" ","pages":""},"PeriodicalIF":0.0,"publicationDate":"2024-08-05","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141898906","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Treatment of Nocardia Chorioretinitis Related Choroidal Neovascularization with Aflibercept: A Case of Unveiled Immunocompromise with anti-GM-CSF Antibodies. 用 Aflibercept 治疗诺卡氏脉络膜视网膜炎相关脉络膜新生血管：抗GM-CSF抗体揭示免疫功能低下的病例。

Retinal Cases and Brief Reports Pub Date : 2024-08-02 DOI: 10.1097/ICB.0000000000001646

Edward Korot, Katherine E Jaje, Neena Singhal, Maria C Miglio

{"title":"Treatment of Nocardia Chorioretinitis Related Choroidal Neovascularization with Aflibercept: A Case of Unveiled Immunocompromise with anti-GM-CSF Antibodies.","authors":"Edward Korot, Katherine E Jaje, Neena Singhal, Maria C Miglio","doi":"10.1097/ICB.0000000000001646","DOIUrl":"https://doi.org/10.1097/ICB.0000000000001646","url":null,"abstract":"Purpose: The purpose of this study was to describe a case of Nocardia chorioretinitis-related choroidal neovascularization (CNV) in a patient with anti-GM-CSF antibodies with resolution of choroidal neovascularization and visual recovery following a series of intravitreal anti-vascular endothelial growth factor.Methods: This study is a case report.Results: In our case, a 50-year-old female, thought to be immunocompetent, presented with metamorphopsia and decreased visual acuity in the left eye in the setting of disseminated Nocardiosis. She had evidence of a subfoveal Nocardia lesion with subretinal fluid and CNV. Following a series of off-label injections with aflibercept, the patient had improvement in lesion size, exudation, and visual acuity. Extensive workup yielded underlying immunocompromise due to presence of anti-GM-CSF antibodies, likely predisposing her to disseminated Nocardiosis.Conclusion: The use of aflibercept in Nocardia chorioretinitis led to resolution of neovascular activity with visual recovery in a patient with disseminated Nocardiosis.","PeriodicalId":53580,"journal":{"name":"Retinal Cases and Brief Reports","volume":" ","pages":""},"PeriodicalIF":0.0,"publicationDate":"2024-08-02","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141879775","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Secondary Multiple Evanescent White Dot Syndrome Following Blunt Trauma. 钝器创伤后的继发性多发白点综合征

Retinal Cases and Brief Reports Pub Date : 2024-08-02 DOI: 10.1097/ICB.0000000000001648

Samantha R Goldburg, Jennifer Adeghate, Gaetano R Barile, Talia R Kaden

{"title":"Secondary Multiple Evanescent White Dot Syndrome Following Blunt Trauma.","authors":"Samantha R Goldburg, Jennifer Adeghate, Gaetano R Barile, Talia R Kaden","doi":"10.1097/ICB.0000000000001648","DOIUrl":"https://doi.org/10.1097/ICB.0000000000001648","url":null,"abstract":"Purpose: To report a case of secondary unilateral MEWDS following blunt trauma to the eye.Methods: Observational case report of one patient.Results: A 25-year-old male initially presented after being hit in the left eye with a football, with visual acuity of 20/50, traumatic iritis, commotio retinae, vitreous hemorrhage, and a large pigment epithelial detachment in the superior macula. He was lost to follow-up for two years before presenting with a sudden decrease in vision. On exam, best corrected VA (BCVA) was counting fingers and clinical exam demonstrated fibrosis in the superior macula, small white lesions around the optic disc and throughout the posterior pole, and ellipsoid zone disruption on OCT. Given the clinical appearance, a diagnosis of Multiple Evanescent White Dot Syndrome was made and the decision was made to observe. Two months later, without treatment, BCVA improved to 20/20, and there was resolution of the white lesions in the posterior pole as well as improved continuity of the ellipsoid zone on OCT.Discussion: We describe a case of Multiple Evanescent White Dot Syndrome two years after blunt trauma to the eye; a far longer latency than previously reported cases of MEWDS secondary to blunt trauma.","PeriodicalId":53580,"journal":{"name":"Retinal Cases and Brief Reports","volume":" ","pages":""},"PeriodicalIF":0.0,"publicationDate":"2024-08-02","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141879774","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Improvement of Tamoxifen Induced Foveal Cavitation with Topical Dorzolamide Therapy. 使用局部多佐胺疗法改善他莫昔芬诱发的眼窝凹陷。

Retinal Cases and Brief Reports Pub Date : 2024-07-29 DOI: 10.1097/ICB.0000000000001645

Khalil Ghasemi Falavarjani, David Sarraf

引用次数: 0

Autologous Tenon's capsule graft for the management of subfoveal detachment due to myopic paracentral macular break. 自体腱膜囊移植治疗近视旁中心黄斑破裂引起的眼底脱离。

Retinal Cases and Brief Reports Pub Date : 2024-07-25 DOI: 10.1097/ICB.0000000000001635

Jorge Fernández-Engroba, Ester Roquet, Pedro Tañá-Sanz, Bernat Nadal, Jeroni Nadal

引用次数: 0

A case of AZOOR under immunomodulatory treatment. 一个接受免疫调节治疗的 AZOOR 病例。

Retinal Cases and Brief Reports Pub Date : 2024-07-23 DOI: 10.1097/ICB.0000000000001643

David A Merle, Lasse Wolfram, Emil Nasyrov, Milda Reith, Martin Kowalski, Melanie Kempf, Lisa Strudel, Deshka Doycheva, Christoph Deuter, Katarina Stingl, Laura Kühlewein

{"title":"A case of AZOOR under immunomodulatory treatment.","authors":"David A Merle, Lasse Wolfram, Emil Nasyrov, Milda Reith, Martin Kowalski, Melanie Kempf, Lisa Strudel, Deshka Doycheva, Christoph Deuter, Katarina Stingl, Laura Kühlewein","doi":"10.1097/ICB.0000000000001643","DOIUrl":"10.1097/ICB.0000000000001643","url":null,"abstract":"Purpose: To describe the clinical course and treatment response of a case of Acute Zonal Occult Outer Retinopathy (AZOOR).Methods: This is an observational case report. The examinations included ophthalmic examination, longitudinal multimodal imaging, visual field testing, electrophysiological recordings, serologic analyses and whole genome sequencing.Results: In this report, the authors present the case of an otherwise healthy 33-year-old female with bilateral AZOOR manifestation. Other possible causes of the observed retinal lesions were ruled out by extensive diagnostic work-up. Treatment with oral prednisolone therapy led to temporal disease control but progression was observed after prednisolone discontinuation. A tapered oral prednisolone therapy in combination with adalimumab initiation prevented further progression for at least 21 months.Conclusion: Diagnosis of AZOOR is frequently complicated by the unspecific symptoms of the disease and significant number of differential diagnoses. Complete diagnostic work-up is important to rule out other etiologies. Due to the lack of randomized controlled trials, therapeutic decisions obligatorily rely on empiric treatment decisions in combination with frequent follow-up examinations.","PeriodicalId":53580,"journal":{"name":"Retinal Cases and Brief Reports","volume":" ","pages":""},"PeriodicalIF":0.0,"publicationDate":"2024-07-23","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141767986","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0