Nour Boungab, Adélaïde Toutee, Youssef Gourinda, Michel Paques, Sarah Mrejen
{"title":"AZOOR患者脉络膜新生血管。","authors":"Nour Boungab, Adélaïde Toutee, Youssef Gourinda, Michel Paques, Sarah Mrejen","doi":"10.1097/ICB.0000000000001815","DOIUrl":null,"url":null,"abstract":"<p><strong>Purpose: </strong>To report mul4modal imaging features in a case of an acute zonal occult outer re4nopathy (AZOOR) complicated with choroidal neovascularization during a follow-up of 18 months.</p><p><strong>Methods: </strong>A 53-year-old woman was referred for bilateral decreased vision and photopsia.Fundus examina4on showed a circular posterior lesion with a far-peripheral lesion in the right eye and a single peripapillary lesion in the leb eye. The lesions were depigmented in both eyes, bordered by an interrupted yellow-orange line in a beaded appearance. The right eye featured macular atrophy with pigmentary migra4on.</p><p><strong>Results: </strong>Clinical examina4on, autofluorescence and angiography confirmed the diagnosis of AZOOR. OCT-B scan and angiography OCT confirmed the presence of an ac4ve choroidal neovascularization in the right eye. Intravitreal an4-VEGF was injected in the right eye with a favorable response.</p><p><strong>Conclusion: </strong>AZOOR is a rare re4nal en4ty with a poorly understood pathogenic mechanism. Choroidal neovascularization is an extremely rare complica4on in AZOOR. We describe mul4modal imaging features of AZOOR with choroidal neovascularization treated by an4-VEGF.</p>","PeriodicalId":53580,"journal":{"name":"Retinal Cases and Brief Reports","volume":" ","pages":""},"PeriodicalIF":0.0000,"publicationDate":"2025-09-23","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"0","resultStr":"{\"title\":\"Choroidal neovascularization in AZOOR.\",\"authors\":\"Nour Boungab, Adélaïde Toutee, Youssef Gourinda, Michel Paques, Sarah Mrejen\",\"doi\":\"10.1097/ICB.0000000000001815\",\"DOIUrl\":null,\"url\":null,\"abstract\":\"<p><strong>Purpose: </strong>To report mul4modal imaging features in a case of an acute zonal occult outer re4nopathy (AZOOR) complicated with choroidal neovascularization during a follow-up of 18 months.</p><p><strong>Methods: </strong>A 53-year-old woman was referred for bilateral decreased vision and photopsia.Fundus examina4on showed a circular posterior lesion with a far-peripheral lesion in the right eye and a single peripapillary lesion in the leb eye. The lesions were depigmented in both eyes, bordered by an interrupted yellow-orange line in a beaded appearance. The right eye featured macular atrophy with pigmentary migra4on.</p><p><strong>Results: </strong>Clinical examina4on, autofluorescence and angiography confirmed the diagnosis of AZOOR. OCT-B scan and angiography OCT confirmed the presence of an ac4ve choroidal neovascularization in the right eye. Intravitreal an4-VEGF was injected in the right eye with a favorable response.</p><p><strong>Conclusion: </strong>AZOOR is a rare re4nal en4ty with a poorly understood pathogenic mechanism. Choroidal neovascularization is an extremely rare complica4on in AZOOR. We describe mul4modal imaging features of AZOOR with choroidal neovascularization treated by an4-VEGF.</p>\",\"PeriodicalId\":53580,\"journal\":{\"name\":\"Retinal Cases and Brief Reports\",\"volume\":\" \",\"pages\":\"\"},\"PeriodicalIF\":0.0000,\"publicationDate\":\"2025-09-23\",\"publicationTypes\":\"Journal Article\",\"fieldsOfStudy\":null,\"isOpenAccess\":false,\"openAccessPdf\":\"\",\"citationCount\":\"0\",\"resultStr\":null,\"platform\":\"Semanticscholar\",\"paperid\":null,\"PeriodicalName\":\"Retinal Cases and Brief Reports\",\"FirstCategoryId\":\"1085\",\"ListUrlMain\":\"https://doi.org/10.1097/ICB.0000000000001815\",\"RegionNum\":0,\"RegionCategory\":null,\"ArticlePicture\":[],\"TitleCN\":null,\"AbstractTextCN\":null,\"PMCID\":null,\"EPubDate\":\"\",\"PubModel\":\"\",\"JCR\":\"Q3\",\"JCRName\":\"Medicine\",\"Score\":null,\"Total\":0}","platform":"Semanticscholar","paperid":null,"PeriodicalName":"Retinal Cases and Brief Reports","FirstCategoryId":"1085","ListUrlMain":"https://doi.org/10.1097/ICB.0000000000001815","RegionNum":0,"RegionCategory":null,"ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"Q3","JCRName":"Medicine","Score":null,"Total":0}
Purpose: To report mul4modal imaging features in a case of an acute zonal occult outer re4nopathy (AZOOR) complicated with choroidal neovascularization during a follow-up of 18 months.
Methods: A 53-year-old woman was referred for bilateral decreased vision and photopsia.Fundus examina4on showed a circular posterior lesion with a far-peripheral lesion in the right eye and a single peripapillary lesion in the leb eye. The lesions were depigmented in both eyes, bordered by an interrupted yellow-orange line in a beaded appearance. The right eye featured macular atrophy with pigmentary migra4on.
Results: Clinical examina4on, autofluorescence and angiography confirmed the diagnosis of AZOOR. OCT-B scan and angiography OCT confirmed the presence of an ac4ve choroidal neovascularization in the right eye. Intravitreal an4-VEGF was injected in the right eye with a favorable response.
Conclusion: AZOOR is a rare re4nal en4ty with a poorly understood pathogenic mechanism. Choroidal neovascularization is an extremely rare complica4on in AZOOR. We describe mul4modal imaging features of AZOOR with choroidal neovascularization treated by an4-VEGF.