Retinal Cases and Brief Reports最新文献

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A CASE OF RHEGMATOGENOUS RETINAL DETACHMENT IN CHRONIC MYELOID LEUKEMIA. 一例慢性髓性白血病血红蛋白性视网膜脱离病例
Retinal Cases and Brief Reports Pub Date : 2025-05-01 DOI: 10.1097/ICB.0000000000001562
Nenita Maganti, Gordon S Crabtree, Jonathan S Chang, Kathleen R Schildroth
{"title":"A CASE OF RHEGMATOGENOUS RETINAL DETACHMENT IN CHRONIC MYELOID LEUKEMIA.","authors":"Nenita Maganti, Gordon S Crabtree, Jonathan S Chang, Kathleen R Schildroth","doi":"10.1097/ICB.0000000000001562","DOIUrl":"10.1097/ICB.0000000000001562","url":null,"abstract":"<p><strong>Purpose: </strong>Chronic myeloid leukemia (CML) is a myeloproliferative neoplasm characterized by uncontrolled proliferation of granulocytes, caused the BCR-ABL1 fusion gene. While ocular manifestations of CML are rare, the presentations can range from asymptomatic to sudden vision loss. Chronic myeloid leukemia-associated ocular findings that have been reported include retinal hemorrhages, leukemic infiltrates, and optic disc edema, but a rhegmatogenous retinal detachment in the setting of CML has not been described.</p><p><strong>Methods: </strong>This was a case report.</p><p><strong>Results: </strong>A 21-year-old man presented with intermittent vision loss in his right eye, tinnitus in the right ear, and abdominal distension. Workup revealed significant leukocytosis, splenomegaly, and a positive BCR-ABL1 mutation. He was diagnosed with CML and started on systemic therapy. Examination of the right eye revealed a large intraocular mass. After 2 weeks of systemic treatment, the large elevation in the right eye had improved, allowing visualization of diffuse subretinal whitening. At follow-up, a rhegmatogenous retinal detachment secondary to an atrophic hole in an area of prior subretinal infiltrates was noted. He underwent repair with a scleral buckle. Postoperative course was complicated by redetachment with proliferative vitreoretinopathy, which led to an unrepairable detachment, despite multiple surgeries with silicone oil tamponade.</p><p><strong>Conclusion: </strong>Ocular findings related to CML are rare, with the lowest incidence when compared with other leukemias, and are associated with worse outcomes. Posterior segment findings include intraretinal hemorrhages, Roth spots, and retinal infiltrates. This unique case describes a rhegmatogenous retinal detachment in CML retinopathy with an aggressive course and poor anatomical result.</p>","PeriodicalId":53580,"journal":{"name":"Retinal Cases and Brief Reports","volume":" ","pages":"346-348"},"PeriodicalIF":0.0,"publicationDate":"2025-05-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140029585","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
CENTRAL RETINAL ARTERY OCCLUSION AFTER CARDIOVERSION OF ATRIAL FIBRILLATION. 心房颤动心脏复律后视网膜中央动脉闭塞。
Retinal Cases and Brief Reports Pub Date : 2025-05-01 DOI: 10.1097/ICB.0000000000001559
Lilia Lagha, Dimitrios Kalogeropoulos, Srinivas Goverdhan, Andrew J Lotery
{"title":"CENTRAL RETINAL ARTERY OCCLUSION AFTER CARDIOVERSION OF ATRIAL FIBRILLATION.","authors":"Lilia Lagha, Dimitrios Kalogeropoulos, Srinivas Goverdhan, Andrew J Lotery","doi":"10.1097/ICB.0000000000001559","DOIUrl":"10.1097/ICB.0000000000001559","url":null,"abstract":"<p><strong>Purpose: </strong>To describe a rare case of unilateral central retinal artery occlusion in the postprocedural period of electrical cardioversion (CV) for atrial fibrillation.</p><p><strong>Methods: </strong>History and ophthalmic examination.</p><p><strong>Results: </strong>A 79-year-old female underwent electrical cardioversion. This resulted in the restoration of sinus rhythm. Ten days after the cardioversion, the patient experienced sudden vision loss in her right eye. She was diagnosed with a right occipital infarct. and a right central retinal artery occlusion.</p><p><strong>Conclusion: </strong>Central retinal artery occlusion is a rare complication of cardioversion that can lead to severe visual loss in the affected eye.</p>","PeriodicalId":53580,"journal":{"name":"Retinal Cases and Brief Reports","volume":" ","pages":"294-296"},"PeriodicalIF":0.0,"publicationDate":"2025-05-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140121385","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
BILATERAL CHOROIDAL DETACHMENTS FOLLOWING NOVEL CHIMERIC ANTIGEN RECEPTOR T-CELL IMMUNOTHERAPY REGIMEN. 新型 CAR T 细胞免疫疗法治疗后的双侧脉络膜脱离。
Retinal Cases and Brief Reports Pub Date : 2025-05-01 DOI: 10.1097/ICB.0000000000001558
Timothy J Goblirsch, Vincent Huang, Albert Maguire, Apoorv P Chebolu
{"title":"BILATERAL CHOROIDAL DETACHMENTS FOLLOWING NOVEL CHIMERIC ANTIGEN RECEPTOR T-CELL IMMUNOTHERAPY REGIMEN.","authors":"Timothy J Goblirsch, Vincent Huang, Albert Maguire, Apoorv P Chebolu","doi":"10.1097/ICB.0000000000001558","DOIUrl":"10.1097/ICB.0000000000001558","url":null,"abstract":"<p><strong>Background/purpose: </strong>The aim of this study was to describe a vision-threatening adverse event of a novel chimeric antigen receptor T-cell immunotherapy for metastatic prostate cancer.</p><p><strong>Methods: </strong>This was an observational case report.</p><p><strong>Results: </strong>A 77-year-old male patient with a history of metastatic prostate cancer and pulmonary embolism enrolled in a clinical trial investigating the use of chimeric antigen receptor T-cell immunotherapy for treatment of metastatic prostate cancer presented with a subjective left temporal visual disturbance. The patient was found to have bilateral extensive choroidal detachments on examination. Optical coherence tomography macula demonstrated no intraretinal fluid or supraretinal fluid in both eyes. B-scan of both eyes redemonstrated choroidal detachments in both eyes and no retinal detachment in either eye. The patient was initiated on a topical and systemic steroid regimen and experienced symptomatic and clinical improvement.</p><p><strong>Conclusion: </strong>The authors exhibit a case of bilateral choroidal detachments secondary to systemic reaction to a novel immunotherapy for metastatic cancer successfully treated with systemic and topical steroids. A close follow-up may be required for patients receiving similar novel immunotherapeutic regimens.</p>","PeriodicalId":53580,"journal":{"name":"Retinal Cases and Brief Reports","volume":" ","pages":"342-345"},"PeriodicalIF":0.0,"publicationDate":"2025-05-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140029586","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
EN FACE DEPTH-RESOLVED OPTICAL COHERENCE TOMOGRAPHY ANGIOGRAPHY MONITORING OF MACULAR OUTER RETINAL DEPOSITS IN A CASE OF MULTIFOCAL CHOROIDITIS MIMICKING SYPHILITIC UVEITIS. 模拟梅毒性葡萄膜炎的多局点脉络膜炎的面深分辨光学相干断层血管造影监测黄斑外视网膜沉积物。
Retinal Cases and Brief Reports Pub Date : 2025-05-01 Epub Date: 2024-03-27 DOI: 10.1097/ICB.0000000000001576
Christian Akotoye, Sandra Hoyek, Itika Garg, Nakul Singh, John B Miller, Lucia Sobrin, Nimesh A Patel
{"title":"EN FACE DEPTH-RESOLVED OPTICAL COHERENCE TOMOGRAPHY ANGIOGRAPHY MONITORING OF MACULAR OUTER RETINAL DEPOSITS IN A CASE OF MULTIFOCAL CHOROIDITIS MIMICKING SYPHILITIC UVEITIS.","authors":"Christian Akotoye, Sandra Hoyek, Itika Garg, Nakul Singh, John B Miller, Lucia Sobrin, Nimesh A Patel","doi":"10.1097/ICB.0000000000001576","DOIUrl":"https://doi.org/10.1097/ICB.0000000000001576","url":null,"abstract":"<p><strong>Purpose: </strong>Multifocal choroiditis is a rare inflammatory condition characterized by retinal and choroidal lesions that may present similarly to ocular pathology of various etiologies. Here, we present a case of multifocal choroiditis mimicking syphilitic uveitis with unique en face optical coherence tomography angiography imaging characteristics.</p><p><strong>Methods: </strong>This was a case report.</p><p><strong>Results: </strong>A 61-year-old woman presented with blurry vision, floaters, and multiple whitish subretinal deposits on en face swept-source optical coherence tomography angiography in the left eye. Fluorescent treponemal antibody test absorption was positive, which led to the initial diagnosis of syphilitic uveitis and subsequent treatment with IV penicillin. During follow-up, optical coherence tomography angiography of the left eye revealed the development of a new choroidal neovascular membrane and new punched-out lesions in the posterior pole. The patient was eventually diagnosed with multifocal choroiditis and treated with aflibercept injections.</p><p><strong>Conclusion: </strong>Immune-mediated uveitis can simulate infectious and neoplastic uveitis. En face optical coherence tomography angiography is a unique imaging modality that allowed for the complete characterization and monitoring of the submacular deposits. This expands the clinical spectrum of multifocal choroiditis.</p>","PeriodicalId":53580,"journal":{"name":"Retinal Cases and Brief Reports","volume":"19 3","pages":"304-310"},"PeriodicalIF":0.0,"publicationDate":"2025-05-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144043074","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
BOUCHER-NEUHAUSER SYNDROME: CHORIORETINAL CHANGES IN A SINGLE CASE OVER TIME. 布歇-诺伊豪泽综合征:单个病例随着时间推移发生的脉络膜视网膜变化
Retinal Cases and Brief Reports Pub Date : 2025-05-01 DOI: 10.1097/ICB.0000000000001556
Jennifer O Adeghate, Jerome Sherman, Sherry Bass, James Liu, Robert B Hufnagel, Lawrence A Yannuzzi
{"title":"BOUCHER-NEUHAUSER SYNDROME: CHORIORETINAL CHANGES IN A SINGLE CASE OVER TIME.","authors":"Jennifer O Adeghate, Jerome Sherman, Sherry Bass, James Liu, Robert B Hufnagel, Lawrence A Yannuzzi","doi":"10.1097/ICB.0000000000001556","DOIUrl":"10.1097/ICB.0000000000001556","url":null,"abstract":"<p><strong>Purpose: </strong>The aim of this study was to describe chorioretinal changes in a single case of Boucher-Neuhauser syndrome over 45 years of follow-up.</p><p><strong>Methods: </strong>Retrospective chart review was performed. Color fundus photography from 1977 to 2003 was obtained and digitized. Current fundus photography was obtained with widefield imaging. High-resolution spectral-domain optical coherence tomography was performed. Genetic analysis was performed using an inherited retinal disorders panel.</p><p><strong>Results: </strong>Fundus examination demonstrated central chorioretinal atrophy with sclerotic choroidal vessels. Short posterior ciliary arteries became more prominent and tortuous over time. Mid-peripheral atrophy extends to the equator and demonstrates a scalloped pattern with islands of atrophy intervening with areas of normal retina. The far periphery remained minimally affected. High-resolution optical coherence tomography demonstrated outer retinal atrophy and choriocapillaris loss. Genetic testing showed a homozygous variant for patatin-like phospholipase domain-containing 6 and a heterozygous variant for tyrosinase-related protein 1.</p><p><strong>Conclusion: </strong>Chorioretinal changes in Boucher-Neuhauser syndrome vary in onset and severity. It is important to diagnose this condition to begin timely management of visual and systemic sequelae.</p>","PeriodicalId":53580,"journal":{"name":"Retinal Cases and Brief Reports","volume":" ","pages":"366-371"},"PeriodicalIF":0.0,"publicationDate":"2025-05-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11377864/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140050983","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Intrafamilial Variability of IMPG1-Associated Vitelliform Dystrophy. impg1相关卵黄营养不良的家族内变异性。
Retinal Cases and Brief Reports Pub Date : 2025-04-25 DOI: 10.1097/ICB.0000000000001772
Lilian Chan, Mattie Adams, Tomas S Aleman, Steven M Bloom
{"title":"Intrafamilial Variability of IMPG1-Associated Vitelliform Dystrophy.","authors":"Lilian Chan, Mattie Adams, Tomas S Aleman, Steven M Bloom","doi":"10.1097/ICB.0000000000001772","DOIUrl":"https://doi.org/10.1097/ICB.0000000000001772","url":null,"abstract":"<p><strong>Purpose: </strong>To describe the clinical and multimodal imaging findings of two siblings with different vitelliform phenotypes associated with a novel IMPG1 gene deletion.</p><p><strong>Methods: </strong>Case series of two siblings. Patients underwent standard optical coherence tomography (OCT), fundus color and short-wavelength fundus autofluorescence (SW-FAF) imaging, fluorescein angiography, and genetic testing for a panel of inherited retinal disorders.</p><p><strong>Results: </strong>A 43-year-old brother and his 41-year-old sister were found to have bilateral vitelliform lesions. The brother presented with single bilateral foveal lesions whereas his asymptomatic sister had multifocal extrafoveal lesions. OCT imaging demonstrated classic subretinal vitelliform lesions in various stages. SW-FAF confirmed that the lesions were hyperautofluorescent. Genetic testing identified an identical heterozygous exon 7 deletion of IMPG1 in both patients.</p><p><strong>Conclusion: </strong>Segregation of a novel deletion in exon 7 of IMPG1 in a family with a vitelliform macular dystrophy, together with a previously reported similar phenotype in patients with heterozygous nucleotide changes within this region of the gene supports the pathogenicity of this variant. Intrafamilial variability in the topography of the lesions with multifocality in one of the siblings suggests retina-wide abnormalities with individual modifiers modulating disease expression.</p>","PeriodicalId":53580,"journal":{"name":"Retinal Cases and Brief Reports","volume":" ","pages":""},"PeriodicalIF":0.0,"publicationDate":"2025-04-25","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144058034","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Intraretinal Fibrosis in Macular Telangiectasia Type-2 (MacTel): Clinical and Multimodal Imaging Features. 黄斑毛细血管扩张2型(MacTel)的视网膜内纤维化:临床和多模式成像特征。
Retinal Cases and Brief Reports Pub Date : 2025-04-24 DOI: 10.1097/ICB.0000000000001768
Kiran Chandran, Anantharaman Giridhar, Mahesh Gopalakrishnan, Sobha Sivaprasad
{"title":"Intraretinal Fibrosis in Macular Telangiectasia Type-2 (MacTel): Clinical and Multimodal Imaging Features.","authors":"Kiran Chandran, Anantharaman Giridhar, Mahesh Gopalakrishnan, Sobha Sivaprasad","doi":"10.1097/ICB.0000000000001768","DOIUrl":"https://doi.org/10.1097/ICB.0000000000001768","url":null,"abstract":"<p><strong>Purpose: </strong>To explore the clinical and multimodal imaging characteristics of Intraretinal Fibrosis (IRFib) in Macular Telangiectasia Type-2 (MacTel).</p><p><strong>Methods: </strong>MacTel eyes with IRFib that had multimodal imaging with color fundus photography, multicolor (MC), blue reflectance, spectral-domain optical coherence tomography (OCT), OCT-angiography (OCTA) and fluorescein angiography.</p><p><strong>Results: </strong>Seven eyes of 6 patients were included. Clinically, all cases had grayish-white fibrosis at macula, with retinal vessel tortuosity in two cases best characterized on MC. Two eyes each belonged to Gass and Blodi stages 3 and 4, three eyes were stage 5 MacTel. The mean lesion area at presentation was 1.36 ± 0.81 mm2 (range 0.56-2.99 mm2). The defining OCT finding for IRFib was hyper-reflective distortion intraretinally (involving different layers). Other accompanying findings in decreasing order were collapse sign (7 eyes); epiretinal membrane (6 eyes); pigment clumping and migration (5 eyes); serrated internal limiting membrane and outer-retinal hyper-reflectivity (4 eyes); and lamellar macular hole (1 eye). On OCTA, IRFib was associated with right-angled vessels, vascular invasion and distortion of foveal avascular zone (FAZ), and vessel dilatation and tortuosity in superficial vascular complex; telangiectasia, FAZ distortion and invasion, vessel drag, capillary looping, and abnormal vascular structures in deep capillary plexus; and nodular tuft or twig-like hyper-reflective vascular lesions in outer-retina choriocapillaris slab.</p><p><strong>Conclusion: </strong>The incidence of IRFib on MC in our MacTel cohort was 1.75% with characteristic findings on OCT and OCTA. They are associated with advanced MacTel and probably implicate Müller cell dysfunction, activated glial cells, and vascular changes during the disease process.</p>","PeriodicalId":53580,"journal":{"name":"Retinal Cases and Brief Reports","volume":" ","pages":""},"PeriodicalIF":0.0,"publicationDate":"2025-04-24","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144058521","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Optic disc pit: A trigger for secondary multiple evanescent white dot syndrome. 视盘窝:继发性多发消失性白点综合征的诱因。
Retinal Cases and Brief Reports Pub Date : 2025-04-23 DOI: 10.1097/ICB.0000000000001771
Shivesh Varma, Royce W S Chen, Jeffrey M Liebmann, Lawrence A Yannuzzi
{"title":"Optic disc pit: A trigger for secondary multiple evanescent white dot syndrome.","authors":"Shivesh Varma, Royce W S Chen, Jeffrey M Liebmann, Lawrence A Yannuzzi","doi":"10.1097/ICB.0000000000001771","DOIUrl":"https://doi.org/10.1097/ICB.0000000000001771","url":null,"abstract":"<p><strong>Purpose: </strong>We describe a case of secondary multiple evanescent white dot syndrome (MEWDS) with optic disc pit as the underlying triggering pathology.</p><p><strong>Methods: </strong>Observational case report.</p><p><strong>Results: </strong>A 41-year-old well man with a background of right optic disc pit presented with right eye loss of vision and photopsia. Visual acuity at presentation was 20/100. He was found to have clinical and multimodal imaging features consistent with right unilateral MEWDS, and the spatial distribution of lesions made it likely that the optic disc pit was the trigger. Fundus autofluorescence revealed hyperautofluorescent 'spots' that gradually faded over serial imaging, with the complete absence of hyperautofluorescent 'dots'. Over three months of follow-up visual acuity recovered to 20/25.</p><p><strong>Conclusion: </strong>Optic disc pit may act as a trigger for secondary MEWDS, which is an increasingly recognized epiphenomenon. Secondary MEWDS may present as 'spots without dots', and we hypothesize that this feature may differentiate it from primary MEWDS.</p>","PeriodicalId":53580,"journal":{"name":"Retinal Cases and Brief Reports","volume":" ","pages":""},"PeriodicalIF":0.0,"publicationDate":"2025-04-23","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144017763","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Subretinal lavage during diagnostic vitrectomy: an adjunctive technique for cell sampling in suspected vitreoretinal lymphoma. 诊断性玻璃体切除术期间视网膜下灌洗:一种疑似玻璃体视网膜淋巴瘤细胞取样的辅助技术。
Retinal Cases and Brief Reports Pub Date : 2025-04-23 DOI: 10.1097/ICB.0000000000001766
Lorenzo Iuliano, Alessandro Marchese, Elisabetta Miserocchi, Eleonora Corbelli, Lucia Bongiovanni, Maurilio Ponzoni, Francesco Bandello, Marco Codenotti
{"title":"Subretinal lavage during diagnostic vitrectomy: an adjunctive technique for cell sampling in suspected vitreoretinal lymphoma.","authors":"Lorenzo Iuliano, Alessandro Marchese, Elisabetta Miserocchi, Eleonora Corbelli, Lucia Bongiovanni, Maurilio Ponzoni, Francesco Bandello, Marco Codenotti","doi":"10.1097/ICB.0000000000001766","DOIUrl":"https://doi.org/10.1097/ICB.0000000000001766","url":null,"abstract":"<p><strong>Purpose: </strong>Current diagnostic methods for vitreoretinal lymphoma (VRL) with predominant subretinal involvement exhibit limited sensitivity. We introduce a novel subretinal lavage technique intended to enhance diagnostic yields during vitrectomy procedures.</p><p><strong>Methods: </strong>During diagnostic vitrectomy, 0.1-0.3 ml of balanced saline solution (BSS) is injected into the subretinal space, creating a localized retinal detachment. Immediately thereafter, the diluted cellular suspension is gently aspirated manually using a 41-gauge extendable soft needle.</p><p><strong>Results: </strong>The technique was successfully performed in three patients without complications, consistently yielding approximately 0.3 ml of lymphoma cell-enriched fluid. Cytological analysis confirmed the presence of CD20-positive B lymphocytes and the MYD88 L265P mutation in all cases. Vitreous cytology was concurrently positive in two out of the three patients.</p><p><strong>Conclusions: </strong>Subretinal lavage is a safe, straightforward, and effective adjunct to standard vitreous biopsy, significantly improving diagnostic accuracy in VRL cases characterized by predominant subretinal infiltration. Implementation of this technique may lead to improved clinical decision-making and patient outcomes.</p>","PeriodicalId":53580,"journal":{"name":"Retinal Cases and Brief Reports","volume":" ","pages":""},"PeriodicalIF":0.0,"publicationDate":"2025-04-23","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144008393","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
WHIPLASH MACULOPATHY: STRUCTURAL SEQUELAE AND THE CORRESPONDING VISUAL IMPAIRMENT, DOCUMENTED WITH OPTICAL COHERENCE TOMOGRAPHY. 鞭状黄斑病变:结构后遗症和相应的视觉损害,用光学相干断层扫描记录。
Retinal Cases and Brief Reports Pub Date : 2025-04-21 DOI: 10.1097/ICB.0000000000001769
Julia Cañas-Martín, Catalina Esmerado, Antonia Sierra, Óscar Segura, Natalia Procházka, Mercè Fossas
{"title":"WHIPLASH MACULOPATHY: STRUCTURAL SEQUELAE AND THE CORRESPONDING VISUAL IMPAIRMENT, DOCUMENTED WITH OPTICAL COHERENCE TOMOGRAPHY.","authors":"Julia Cañas-Martín, Catalina Esmerado, Antonia Sierra, Óscar Segura, Natalia Procházka, Mercè Fossas","doi":"10.1097/ICB.0000000000001769","DOIUrl":"https://doi.org/10.1097/ICB.0000000000001769","url":null,"abstract":"<p><strong>Purpose: </strong>To explore the natural history of whiplash maculopathy through a clinical case report, emphasizing the role of optical coherence tomography (OCT) in diagnosing and understanding this ocular condition.</p><p><strong>Methods: </strong>A 55-year-old woman presented to the Emergency Service after a head-on collision, reporting decreased visual acuity (VA) in her left eye. VA was 20/20 in the right eye and 20/40 in the left. Funduscopic examination revealed subtle retinal pigment epithelium (RPE) disruption, and OCT showed neurosensory detachment (NSD) with intraretinal cysts.</p><p><strong>Results: </strong>One week later, OCT indicated a slightly unstructured RPE, with no NSD or cysts. Fluorescein angiography was normal, and VA improved to 20/25. A central scotoma was noted in visual field (VF) testing 10 days post-accident. Although VA and OCT nearly normalized two months later, infrared imaging (IR) revealed a hypo-reflective macular area correlating with VF defects. Eight years later, the patient continues exhibiting a persistent central scotoma and subtle outer retinal irregularity on OCT.</p><p><strong>Conclusions: </strong>Whiplash maculopathy, a form of indirect ocular trauma, typically results in temporary visual impairment and central scotoma. Its natural history includes spontaneous improvement, with changes likely arising from vitreoretinal traction forces. This case underscores the long-term retinal changes associated with whiplash injuries.</p>","PeriodicalId":53580,"journal":{"name":"Retinal Cases and Brief Reports","volume":" ","pages":""},"PeriodicalIF":0.0,"publicationDate":"2025-04-21","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144026522","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
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