Retinal Cases and Brief Reports最新文献_第5页

CHOROIDAL NEOVASCULARIZATION AS A LATE COMPLICATION OF SYPHILITIC CHORIORETINITIS MANAGED WITH INTRAVITREAL AFLIBERCEPT. 作为梅毒性脉络膜视网膜炎晚期并发症的脉络膜新生血管，使用玻璃体内阿弗利贝赛普进行治疗。

Retinal Cases and Brief Reports Pub Date : 2024-07-19 DOI: 10.1097/ICB.0000000000001638

Ana Paula Couto, Giovanna Provenzano, Raul N G Vianna

{"title":"CHOROIDAL NEOVASCULARIZATION AS A LATE COMPLICATION OF SYPHILITIC CHORIORETINITIS MANAGED WITH INTRAVITREAL AFLIBERCEPT.","authors":"Ana Paula Couto, Giovanna Provenzano, Raul N G Vianna","doi":"10.1097/ICB.0000000000001638","DOIUrl":"https://doi.org/10.1097/ICB.0000000000001638","url":null,"abstract":"Purpose: To report a rare case of choroidal neovascular membrane (CNV) developed three years after acquired syphilitic chorioretinitis successfully treated with intravitreal aflibercept.Methods: Case report.Results: A 44-year-old woman with bilateral decreased vision and a history of syphilitic chorioretinitis 3 years prior to presentation. Her best-corrected visual acuity was <20/400 in the right eye and 20/70 in the left eye. There was no evidence of anterior chamber or vitreous inflammation. Fundoscopy revealed a fibrovascular macular lesion associated with hemorrhages in both eyes. Optical coherence tomography (OCT) and OCT angiography confirmed the diagnosis of bilateral CNV. After ruling out other systemic diseases, the diagnosis of CNV as a late complication of syphilitic chorioretinitis was established. Although treatment was not recommended in the right eye, the left eye was treated with 3 monthly intravitreal injections of aflibercept as a solo therapy. Three weeks after the last injection, the visual acuity improved to 20/25 and remained stable at the 6-month follow-up with no evidence of CNV reactivation.Conclusion: Choroidal neovascular membranes can occur as a late complication of syphilitic chorioretinitis. Solo treatment with intravitreal injections of the anti-vascular endothelial growth factor aflibercept effectively controlled CNV activity and improved visual acuity.","PeriodicalId":53580,"journal":{"name":"Retinal Cases and Brief Reports","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2024-07-19","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141728289","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Bilateral cystoid macular edema as the presenting feature of chronic myeloid leukemia. 双侧囊样黄斑水肿是慢性髓性白血病的表现特征。

Retinal Cases and Brief Reports Pub Date : 2024-07-19 DOI: 10.1097/ICB.0000000000001640

Ffion E Brown, Ahmed Al-Janabi, Kevin Gallagher

{"title":"Bilateral cystoid macular edema as the presenting feature of chronic myeloid leukemia.","authors":"Ffion E Brown, Ahmed Al-Janabi, Kevin Gallagher","doi":"10.1097/ICB.0000000000001640","DOIUrl":"https://doi.org/10.1097/ICB.0000000000001640","url":null,"abstract":"Purpose: Ophthalmic disease may rarely be a presenting feature of chronic myeloid leukemia (CML).Methods: We report a case of a 53-year-old man with type 1 diabetes mellitus who presented with a rapid onset of bilateral blurred vision.Results: He was noted to have bilateral macular edema and was initially treated for presumed diabetic macular edema (DME) with intravitreal alifbercept injections. One month later, there was complete resolution of his macular edema. Review of his history and imaging revealed features atypical for DME, specifically; the rapid onset of bilateral blurred vision over 2-3 weeks, numerous cotton wool spots within the macula, the absence of any exudates, the symmetrical macular edema with a \"vaulted ceiling\" appearance (more typical of cystoid macular edema) and the dramatic response to a single intravitreal aflibercept injection. One week after his intravitreal injection, the patient was diagnosed with CML following marked leucocytosis on a routine blood test by his general practitioner. Although uncommon, sudden onset bilateral edema in the absence of other chronic diabetic changes should prompt consideration of an underlying haematological cause.Conclusion: This case highlights the importance of considering CML as a differential diagnosis in patients presenting with sudden onset, bilateral cystoid macular oedema. Vigilance is especially important in patients with co-existing diabetic retinopathy as the clinical features of leukemic retinopathy can overlap. Furthermore, the diagnosis of CML in a patient with diabetes mellitus should prompt extra observation for accelerated worsening of diabetic retinopathy.","PeriodicalId":53580,"journal":{"name":"Retinal Cases and Brief Reports","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2024-07-19","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141728288","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Uveal effusion in Waldenstrom's macroglobulinemia. 瓦尔登斯特罗姆巨球蛋白血症的葡萄膜渗出。

Retinal Cases and Brief Reports Pub Date : 2024-07-19 DOI: 10.1097/ICB.0000000000001631

Johanna Darmon, Mickael Anjou, Denis Georgelin, Antoine P Brezin, Dominique Bremond-Gignac

引用次数: 0

Combined 41- gauge surgically induced macular detachment and free internal limiting membrane flap technique for management of refractory full-thickness macular hole. 联合使用 41 号手术诱导黄斑脱离和游离内缘膜瓣技术治疗难治性全厚黄斑孔。

Retinal Cases and Brief Reports Pub Date : 2024-07-19 DOI: 10.1097/ICB.0000000000001637

Laura Di Leo, Beatrice Tombolini, Ilenia Gallo Afflitto, Andrea Vulpetti, Rino Frisina

{"title":"Combined 41- gauge surgically induced macular detachment and free internal limiting membrane flap technique for management of refractory full-thickness macular hole.","authors":"Laura Di Leo, Beatrice Tombolini, Ilenia Gallo Afflitto, Andrea Vulpetti, Rino Frisina","doi":"10.1097/ICB.0000000000001637","DOIUrl":"https://doi.org/10.1097/ICB.0000000000001637","url":null,"abstract":"Purpose: To report a case of anatomic closure and functional improvement in a patient affected by refractory full-thickness macular hole (FTMH) undergone a combined 41-gauge (g) surgically induced macular detachment and free internal limiting membrane (ILM) flap technique.Methods: This is a retrospective case-report of a 70-years-olded woman affected by refractory FTMH who referred to Ophthalmology Unit of Guglielmo da Saliceto Hospital, Piacenza (Italy) in April 2023. The patient underwent a combined 41-g surgically induced macular detachment and free ILM flap. Macular detachment was induced by multiple subretinal injections of balanced salt solution (BSS) by 41-g needle through three retinotomies. Spectral-domain optical coherence tomography (SD-OCT) and best-corrected visual acuity (BCVA) were performed preoperatively and postoperatively at 7th day, 1st and 6th month.Results: On 7th postoperative day, FTMH showed complete closure. BCVA improved from preoperative 20/400 to 20/70 at 6th postoperative month.Discussion: BSS subretinal injection allowed the mobilization and relaxation of retina at the posterior pole. Although the edges of the hole were still detectable, their diameters were inferior to preoperative measurements. Autologous free ILM flap allowed to fill the residual gap into the hole.Conclusion: The final anatomic closure, and the postoperative functional improvement demonstrated the effectiveness of this approach, supporting its indication for refractory FTHM.","PeriodicalId":53580,"journal":{"name":"Retinal Cases and Brief Reports","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2024-07-19","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141728290","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Endoscopic Surgery for Congenital or Acquired Cataract Associated with Persistent Fetal Vasculature: A Case Series. 内窥镜手术治疗与胎儿血管持续存在有关的先天性或后天性白内障：病例系列。

Retinal Cases and Brief Reports Pub Date : 2024-07-19 DOI: 10.1097/ICB.0000000000001634

Mitsuru Otsubo, Tatsushi Kaga, Yoshimi Yokoyama, Takashi Kojima

{"title":"Endoscopic Surgery for Congenital or Acquired Cataract Associated with Persistent Fetal Vasculature: A Case Series.","authors":"Mitsuru Otsubo, Tatsushi Kaga, Yoshimi Yokoyama, Takashi Kojima","doi":"10.1097/ICB.0000000000001634","DOIUrl":"https://doi.org/10.1097/ICB.0000000000001634","url":null,"abstract":"Purpose: Persistent fetal vasculature (PFV) is a congenital malformation caused by a failure in regression of the primary vitreous and hyaloid vessels. An abnormal PFV occurs in the anterior and posterior segments of the eye. Surgery for PFV carries the risk of retinal detachment. We report four cases of cataracts associated with PFV, in which our novel surgical technique with an intraocular endoscope was safely performed.Methods: Lensectomy and vitrectomy were performed in cases 1, 3, and 4, while lensectomy, vitrectomy, and intraocular lens implantation using an endoscope were performed in case 2. In all cases, after lens removal, a slit at the posterior lens capsule was created to avoid the retrolental fibrovascular membrane using underwater electric coagulation. Moreover, the endoscope was inserted, by which the intraocular region was observed to determine the treatment method for the fibrovascular membrane and vitreous stalk. No additional surgeries were required for complications before or after any of the surgeries.Results: Using an endoscope during cataract surgery associated with PFV, observing the vitreous stalk at high magnification and ensuring safe treatment were possible.Conclusions: Endoscopic surgery could be considered an effective method for treating PFV-associated cataracts.","PeriodicalId":53580,"journal":{"name":"Retinal Cases and Brief Reports","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2024-07-19","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141728291","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Intermediate uveitis in common variable immunodeficiency (CVID) associated with a heterozygous variant in the TNFRSF13B gene. 与 TNFRSF13B 基因杂合子变异有关的常见变异性免疫缺陷症（CVID）中级葡萄膜炎。

Retinal Cases and Brief Reports Pub Date : 2024-07-19 DOI: 10.1097/ICB.0000000000001632

Mathijs Osaer, Wim Terryn, Elfride De Baere, Ciel De Vriendt, Filomeen Haerynck, Tessa Kerre, Elke O Kreps

{"title":"Intermediate uveitis in common variable immunodeficiency (CVID) associated with a heterozygous variant in the TNFRSF13B gene.","authors":"Mathijs Osaer, Wim Terryn, Elfride De Baere, Ciel De Vriendt, Filomeen Haerynck, Tessa Kerre, Elke O Kreps","doi":"10.1097/ICB.0000000000001632","DOIUrl":"https://doi.org/10.1097/ICB.0000000000001632","url":null,"abstract":"Purpose: To report on a rare case of intermediate uveitis occurring in a patient with common variable immunodeficiency (CVID) and a heterozygous TNFRSF13B variant.Methods: Observational case report.Results: A 23-year-old male presented with a 3-month history of increasing floaters and blurred vision to both eyes. He had been treated with topical and intravitreal corticosteroids by his local ophthalmologist nine months before. Ocular examination demonstrated bilateral intermediate uveitis with retinal vasculitis. He had been treated with intravenous immunoglobulins during childhood, due to primary humoral immunodeficiency. Systemic work-up for other causes of intermediate uveitis was unremarkable, notably no features of systemic sarcoid-like disease were detected. Initial treatment with mycophenolate mofetil showed insufficient response, and upon switching to adalimumab, clinical remission was achieved. Immunocytometry and genetic work-up revealed a smB+CD21norm subtype of CVID and a heterozygous TNFRSF13B variant.Conclusion: This report of CVID-associated intermediate uveitis in a patient with a heterozygous TNFRSF13B variant highlights the potential involvement of the eye within CVID-associated autoimmunity and the role for anti-TNF blockade in this challenging group of patients.","PeriodicalId":53580,"journal":{"name":"Retinal Cases and Brief Reports","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2024-07-19","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141728292","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Aspergillus Endophthalmitis Secondary to Infectious Scleritis: Utility of Diagnostic PCR. 继发于感染性巩膜炎的眼底曲霉菌病：诊断性 PCR 的实用性。

Retinal Cases and Brief Reports Pub Date : 2024-07-19 DOI: 10.1097/ICB.0000000000001633

Kevin F Elwood, Evan J Warner, Jonathan S Chang, Laura J Kopplin

{"title":"Aspergillus Endophthalmitis Secondary to Infectious Scleritis: Utility of Diagnostic PCR.","authors":"Kevin F Elwood, Evan J Warner, Jonathan S Chang, Laura J Kopplin","doi":"10.1097/ICB.0000000000001633","DOIUrl":"https://doi.org/10.1097/ICB.0000000000001633","url":null,"abstract":"Purpose: To describe a case of delayed-onset Aspergillus fumigatus endophthalmitis secondary to infectious fungal scleritis diagnosed with broad range polymerase chain reaction (PCR) from scleral nodular debridement and vitreous sampling during vitrectomy.Methods: Retrospective case report with slit lamp photography, optical coherence tomography, and fundus photography.Results: A 76-year-old man presented with right eye worsening vision and pain concerning for progressive nodular scleritis and endophthalmitis eight months following a reportedly innocuous tree branch injury. Following the injury, he underwent an MRI, surgical exploration, subconjunctival antibiotic administration, and culturing due to persistent foreign body sensation. Cultures were negative, and the patient was started on oral NSAIDs, oral prednisone, and periocular triamcinolone injections following negative/normal infectious and rheumatologic workup for scleritis. The patient was referred for worsened scleritis with development of endophthalmitis. He underwent lamellar sclerectomy, debridement, and culture of purulent material from scleral nodules in coordination with diagnostic vitrectomy, vitreous sampling, and subconjunctival and intravitreal antibiotic and antifungal treatment. Broad range PCR was positive for Aspergillus fumigatus and targeted antifungal treatment initiated. The eye did not regain visual function and was enucleated for progressive pain six months following diagnosis.Conclusion: Fungal scleritis and endophthalmitis results in significant morbidity. Diagnostic vitrectomy and broad range PCR can aid in prompt diagnosis and targeted treatment, and may be useful in refractory cases.","PeriodicalId":53580,"journal":{"name":"Retinal Cases and Brief Reports","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2024-07-19","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141728286","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

AMNIOTIC MEMBRANE GRAFTING FOR A CASE OF BILATERAL GIANT FULL-THICKNESS MACULAR HOLE IN ALPORT SYNDROME AFTER CATARACT SURGERY. 羊膜移植治疗白内障手术后Alport综合征双侧巨大全层黄斑裂孔一例。

Retinal Cases and Brief Reports Pub Date : 2024-07-01 Epub Date: 2023-10-09 DOI: 10.1097/ICB.0000000000001428

François-Philippe Roubelat, Vincent Gualino, Pierre R Fournié, Vincent J Soler

{"title":"AMNIOTIC MEMBRANE GRAFTING FOR A CASE OF BILATERAL GIANT FULL-THICKNESS MACULAR HOLE IN ALPORT SYNDROME AFTER CATARACT SURGERY.","authors":"François-Philippe Roubelat, Vincent Gualino, Pierre R Fournié, Vincent J Soler","doi":"10.1097/ICB.0000000000001428","DOIUrl":"10.1097/ICB.0000000000001428","url":null,"abstract":"Purpose: The purpose of this study was to describe the surgical management of bilateral giant full-thickness macular hole with sudden onset two months after cataract surgery in a patient with Alport syndrome.Methods: This was an observational, single-case report.Results: A 54-year-old woman with a history of Alport syndrome presented with severe bilateral visual loss two months after cataract surgery. The diagnosis of bilateral giant full-thickness macular hole was made. We found the absence of the internal limiting membrane and the inability to lift and peel a continuous posterior hyaloid sheet during surgical management with 25-gauge pars plana vitrectomy (left eye). Amniotic membrane grafting followed by gas tamponade were performed for hole closure. The hole remained closed but vision was poorly restored two months after.Conclusion: Cataract surgery in patients with Alport syndrome could promote early development of giant full-thickness macular hole. Collagen defects could underlie internal limiting membrane absence and the inability to properly peel the posterior hyaloid.","PeriodicalId":53580,"journal":{"name":"Retinal Cases and Brief Reports","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2024-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11191552/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"41219921","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

A CASE OF HERPES SIMPLEX VIRUS AND CYTOMEGALOVIRUS RETINITIS COINFECTION. 一例单纯疱疹病毒和巨细胞病毒视网膜炎合并感染病例。

Retinal Cases and Brief Reports Pub Date : 2024-07-01 DOI: 10.1097/ICB.0000000000001424

Jennifer Lopez, Hong-Uyen Hua, Brian C Toy

引用次数: 0

FLUID-FLUID EXCHANGE AND EXTERNAL NEEDLE DRAINAGE WITH MINIMAL GAS VITRECTOMY ASSOCIATED WITH RETINAL DISPLACEMENT. 在视网膜移位的情况下进行液体-液体交换和外部针头引流，同时进行微量气体玻璃体切除术。

Retinal Cases and Brief Reports Pub Date : 2024-07-01 DOI: 10.1097/ICB.0000000000001410

Aditya Bansal, Luis C Escaf, Wei Wei Lee, Rajeev H Muni

{"title":"FLUID-FLUID EXCHANGE AND EXTERNAL NEEDLE DRAINAGE WITH MINIMAL GAS VITRECTOMY ASSOCIATED WITH RETINAL DISPLACEMENT.","authors":"Aditya Bansal, Luis C Escaf, Wei Wei Lee, Rajeev H Muni","doi":"10.1097/ICB.0000000000001410","DOIUrl":"10.1097/ICB.0000000000001410","url":null,"abstract":"Purpose: To determine whether fluid-fluid exchange (endodrainage) or external needle drainage can result in retinal displacement following minimal gas vitrectomy (MGV) with no fluid-air exchange for rhegmatogenous retinal detachment repair.Methods: Two patients with macula-off rhegmatogenous retinal detachment underwent MGV with and without segmental buckle. First case had MGV with segmental buckle (MGV-SB), along with endodrainage, whereas the second case had MGV only with external fluid drainage. At the completion of surgery, the patient was immediately log rolled to face down for 6 hours followed by positioning to the break.Results: Both patients achieved retinal reattachment, and postoperative widefield fundus autofluorescence imaging demonstrated a low-integrity retinal attachment with retinal displacement.Conclusion: Iatrogenic fluid drainage techniques, such as fluid-fluid exchange or external needle drainage during MGV (without fluid-air exchange), may result in retinal displacement. Allowing the retinal pigment epithelial pump to reabsorb the fluid naturally may reduce the risk of retinal displacement.","PeriodicalId":53580,"journal":{"name":"Retinal Cases and Brief Reports","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2024-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"9104741","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0