Retinal Cases and Brief Reports最新文献

{"title":"Real-Time Resolution of Bacillary Layer Detachment in Rhegmatogenous Retinal Detachment Following Pneumatic Retinopexy.","authors":"Miguel Cruz-Pimentel, Sueellen Demian, Tomás Minelli, Rajeev H Muni","doi":"10.1097/ICB.0000000000001958","DOIUrl":"10.1097/ICB.0000000000001958","url":null,"abstract":"<p><strong>Purpose: </strong>To describe the in vivo hourly resolution of a bacillary layer detachment (BALAD) with an intact anterior wall in a patient with fovea-off rhegmatogenous retinal detachment (RRD).</p><p><strong>Methods: </strong>Case report.</p><p><strong>Results: </strong>A 58-year-old female patient presented with a fovea-off RRD and foveal BALAD with an intact anterior wall, with visual acuity of counting fingers at 3 feet. She underwent pneumatic retinopexy with an anterior chamber paracentesis and intravitreal injection of 0.6 cc of pure sulfur hexafluoride gas and was instructed to maintain face-down positioning for 6 hours. Hourly swept-source optical coherence tomography (SS-OCT) imaging with the PLEX Elite 9000 (Carl Zeiss, Dublin, California, USA) with high-definition horizontal spotlight scans and 12×12 mm raster scans demonstrated excellent structural recovery of the fovea. At the one-month follow-up, the retina remained attached with visual acuity improving to 20/100. Two months later, visual acuity improved to 20/30. The OCT showed significant recovery of the outer retinal bands, although a small sub foveal defect in the interdigitation zone (IZ) remained.</p><p><strong>Conclusion: </strong>This case highlights the importance of recognizing fovea-off RRD associated with BALAD, particularly when the anterior wall is intact. Urgent intervention can allow for foveal structural recovery potentially preventing the development of a BALAD-lamellar hole and full-thickness macular hole.</p>","PeriodicalId":53580,"journal":{"name":"Retinal Cases and Brief Reports","volume":" ","pages":""},"PeriodicalIF":0.0,"publicationDate":"2026-07-16","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148474153","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Congenital stationary night blindness with a fundus albipunctatus-like yellow-dotted retina associated with compound heterozygous RPE65 variants: A case report.","authors":"Adriana P Pérez Negron, Tamara Juvier-Riesgo, Henar Albertos-Arranz, Audina Berrocal, Carlos E Mendoza-Santiesteban","doi":"10.1097/ICB.0000000000001955","DOIUrl":"10.1097/ICB.0000000000001955","url":null,"abstract":"<p><strong>Purpose: </strong>This case describes congenital stationary night blindness (CSNB) with a fundus albipunctatus-like phenotype linked to compound heterozygous RPE65 variants, highlighting the diagnostic value of multimodal imaging and evidence-based variant interpretation.</p><p><strong>Methods: </strong>A retrospective case review including best-corrected visual acuity (BCVA), color vision testing, fundus photography, spectral-domain optical coherence tomography (SD-OCT), full-field electroretinography (ERG), and next-generation sequencing with parental segregation analysis. Variant pathogenicity was assessed using in-silico prediction models (PolyPhen-2 HumDiv and HumVar), and findings were integrated with clinical and imaging data.</p><p><strong>Results: </strong>A sixteen-year-old male reported lifelong nyctalopia and stable difficulty seeing in dim.</p><p><strong>Environments: </strong>BCVA was 20/30 OD and 20/25 OS with normal color vision. Fundus examination revealed multiple white-yellow flecks along the arcades and mid-periphery with macular sparing. SD-OCT demonstrated preserved outer retinal architecture and an intact ellipsoid zone, and full-field ERG showed preserved rod and cone responses. Genetic testing identified two RPE65 missense variants: c.433G>A (p.Ala145Thr), likely pathogenic, and c.946A>G (p.Asn316Asp), reported as a VUS. PolyPhen-2 analysis classified p.Asn316Asp as damaging (HumDiv/HumVar score 1.000), and parental segregation demonstrated the variants in trans. Integration of genotype and phenotype supports p.Asn316Asp as likely pathogenic.</p><p><strong>Conclusion: </strong>Compound heterozygosity for hypomorphic RPE65 variants can produce a stationary fundus albipunctatus-like phenotype rather than progressive retinal degeneration. Careful integration of multimodal phenotyping and variant interpretation was essential for confirming disease causality.</p>","PeriodicalId":53580,"journal":{"name":"Retinal Cases and Brief Reports","volume":" ","pages":""},"PeriodicalIF":0.0,"publicationDate":"2026-07-14","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148450465","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Acute Paracentral Scotoma Following Cosmetic Penile Filler Injection.","authors":"Samuel Y Lee, A Itzam Marin, Alessandro Feo, Prashant D Tailor, Shahin Faghihi, Kim A Firn, David Sarraf","doi":"10.1097/ICB.0000000000001954","DOIUrl":"https://doi.org/10.1097/ICB.0000000000001954","url":null,"abstract":"<p><strong>Purpose: </strong>To describe macular ischemia following cosmetic penile filler injection due to presumed branch retinal artery occlusion from embolization through a patent foramen ovale (PFO).</p><p><strong>Methods: </strong>Multimodal imaging, including fundus photography, spectral domain optical coherence tomography (OCT), OCT angiography (OCTA), and fluorescein angiography (FA) were performed.</p><p><strong>Results: </strong>A 33-year-old healthy male presented with an acute paracentral scotoma of the left eye (OS) shortly after undergoing an elective cosmetic penile filler injection. Retinal examination and color fundus photography illustrated a cotton wool spot corresponding to the acute scotoma OS. Spectral domain OCT showed corresponding hyperreflectivity of the inner and middle retina OS and paracentral acute middle maculopathy (PAMM). OCTA of the superficial and deep capillary plexus showed corresponding flow deficit and fluorescein angiography illustrated corresponding segmental staining of the retinal arterioles in the macula suggestive of branch retinal artery occlusion (BRAO) OS. Extensive systemic evaluation was unremarkable except for transthoracic echocardiography, which revealed a PFO. Brain magnetic resonance imaging (MRI) was normal and infectious, inflammatory, and hypercoagulable workups were negative.</p><p><strong>Conclusion: </strong>and Importance: This report highlights a case of occlusive vascular maculopathy following distal cosmetic filler injection likely mediated by embolization through a PFO. Arterial occlusive events can occur after elective cosmetic procedures and patients should be counselled accordingly.</p>","PeriodicalId":53580,"journal":{"name":"Retinal Cases and Brief Reports","volume":" ","pages":""},"PeriodicalIF":0.0,"publicationDate":"2026-07-02","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148370993","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"INTRAFAMILIAL VARIABILITY OF IMPG1 -ASSOCIATED VITELLIFORM DYSTROPHY.","authors":"Lilian Chan, Mattie Adams, Tomas S Aleman, Steven M Bloom","doi":"10.1097/ICB.0000000000001772","DOIUrl":"10.1097/ICB.0000000000001772","url":null,"abstract":"<p><strong>Purpose: </strong>To describe the clinical and multimodal imaging findings of two siblings with different vitelliform phenotypes associated with a novel IMPG1 gene deletion.</p><p><strong>Methods: </strong>Case series of two siblings. Patients underwent standard optical coherence tomography, fundus color and short-wavelength fundus autofluorescence imaging, fluorescein angiography, and genetic testing for a panel of inherited retinal disorders.</p><p><strong>Results: </strong>A 43-year-old brother and his 41-year-old sister were found to have bilateral vitelliform lesions. The brother presented with single bilateral foveal lesions whereas his asymptomatic sister had multifocal extrafoveal lesions. Optical coherence tomography imaging demonstrated classic subretinal vitelliform lesions in various stages. Short-wavelength fundus autofluorescence confirmed that the lesions were hyperautofluorescent. Genetic testing identified an identical heterozygous exon 7 deletion of IMPG1 in both patients.</p><p><strong>Conclusion: </strong>Segregation of a novel deletion in exon 7 of IMPG1 in a family with a vitelliform macular dystrophy, together with a previously reported similar phenotype in patients with heterozygous nucleotide changes within this region of the gene supports the pathogenicity of this variant. Intrafamilial variability in the topography of the lesions with multifocality in one of the siblings suggests retina-wide abnormalities with individual modifiers modulating disease expression.</p>","PeriodicalId":53580,"journal":{"name":"Retinal Cases and Brief Reports","volume":" ","pages":"510-514"},"PeriodicalIF":0.0,"publicationDate":"2026-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144058034","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"MEMBRANE RICH IN GROWTH FACTORS FOR THE TREATMENT OF REFRACTORY MACULAR HOLES AND ITS EFFECTS ON RETINAL VASCULATURE AND ANATOMY PRGFM FOR REFRACTORY MACULAR HOLE.","authors":"Brahim A Khouri, Joaquín A Sosa, Yazmín M Báez, Juan Audrey, Jeannette Domínguez, Juan F Batlle, Nassim Abreu","doi":"10.1097/ICB.0000000000001765","DOIUrl":"10.1097/ICB.0000000000001765","url":null,"abstract":"<p><strong>Purpose: </strong>Evaluate the safety and efficacy of membrane rich in growth factors (mPRGF) and its effects on retinal vasculature and anatomy in refractory and poor-prognosis macular holes.</p><p><strong>Methods: </strong>Retrospective, interventional, longitudinal, case series, and single-center study conducted at Dr. Elías Santana Hospital, Dominican Republic. Patients with macular hole larger than 400 μm, refractory or with poor prognosis, were treated with posterior pars plana vitrectomy plus adjuvant therapy mPRGF. A total of seven eyes were included: refractory macular hole (n = 6) and traumatic macular hole (n = 1). The anatomical closure was evaluated by optical coherence tomography and foveal avascular zone, and foveal density was measured with optical coherence tomography angiography pre- and postsurgery. Also, the corrected visual acuity was compared pre- and postintervention.</p><p><strong>Results: </strong>A total of seven eyes were intervened and a surgical-anatomic closure rate was 85.7%. The average corrected visual acuity resulted in an improvement of more than six lines in Snellen notation that was statistically significant ( P = 0.036). Foveal avascular zone and foveal density showed a decrease ( P = 0.002) and increase ( P = 0.043), respectively, after surgery.</p><p><strong>Conclusion: </strong>In conclusion, this clinical research provides compelling evidence supporting the efficacy and safety of mPRGF in achieving the anatomical closure of refractory or traumatic macular holes larger than 400 μm. Notably, mPRGF treatment demonstrated significant improvements in patients' visual acuity and contributed to the restoration of normal retinal vasculature. These exciting results pave the way for the potential utilization of mPRGF as a reproducible and cost-effective adjuvant therapy in the surgical management of macular holes.</p>","PeriodicalId":53580,"journal":{"name":"Retinal Cases and Brief Reports","volume":" ","pages":"545-551"},"PeriodicalIF":0.0,"publicationDate":"2026-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144058522","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"UNILATERAL RETINAL PIGMENT EPITHELIUM DYSGENESIS: NEW CASES, LITERATURE REVIEW, AND CONSIDERATIONS OF THE SIMILARITIES AND DIFFERENCES WITH COMBINED HAMARTOMA OF THE RETINA AND RETINAL PIGMENT EPITHELIUM.","authors":"Salomon Y Cohen, Thomas Lathiere, Victoria Marechal, Francesco Rodriguez, Eric Souied, Carol L Shields","doi":"10.1097/ICB.0000000000001785","DOIUrl":"10.1097/ICB.0000000000001785","url":null,"abstract":"<p><strong>Purpose: </strong>To report new cases of unilateral retinal pigment epithelium dysgenesis (URPED), review the literature, and compare its characteristics with other conditions, including combined hamartoma of the retina and retinal pigment epithelium.</p><p><strong>Methods: </strong>Case reports and analysis of multimodal imaging findings, and complications of URPED.</p><p><strong>Results: </strong>Three new male patients of typical URPED, aged 40 to 75 years, were described. With these new cases, in addition to those previously published, 26 cases in total were reported, highlighting the value of clinical and imaging tools. Clinically, URPED was detected at a mean age of 31 years, mainly in men (15/26, 57%), as a flat pigmented lesion (19/26, 73%), sometimes with a honeycomb pattern of the entire lesion (4/26, 15%), but systematically with spiculated or fringe-like margins (26/26, 100%). The tumor was systematically located at the posterior pole, generally contiguous with the optic disk (23/26, 88%). Fundus autofluorescence and fluorescein angiography systematically showed a characteristic inversion (black/white) of URPED at the spiculated margins. Indocyanine green angiography, electrophysiology, B-scan ultrasonography, and functional tests seemed to be of lesser diagnostic value. Optical coherence tomography showed a normal overlying retina, although retinal thinning with photoreceptor disruption and/or internal limiting membrane irregularities were sometimes observed. Other conditions, including combined hamartoma of the retina and retinal pigment epithelium, retinal hemangioblastoma, RPE adenoma/adenocarcinoma, and ocular trauma sequelae may present with a similar small area of spiculated border, usually associated with retinal thickening and folding, and a dense epiretinal membrane.</p><p><strong>Conclusion: </strong>Unilateral retinal pigment epithelium dysgenesis has typical clinical and imaging features allowing differentiating it from other ocular conditions.</p>","PeriodicalId":53580,"journal":{"name":"Retinal Cases and Brief Reports","volume":" ","pages":"499-509"},"PeriodicalIF":0.0,"publicationDate":"2026-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144683541","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"SINGLE-PORT ILLUMINATED ENDOLASER FOR A LARGE RETINAL BREAK WITH LOCALIZED RETINAL DETACHMENT UNDER WIDE-ANGLE VISUALIZATION WITHOUT VITRECTOMY.","authors":"Young Je Choi, Min Kim","doi":"10.1097/ICB.0000000000001776","DOIUrl":"10.1097/ICB.0000000000001776","url":null,"abstract":"<p><strong>Purpose: </strong>To evaluate the feasibility of single-port illuminated endolaser photocoagulation using wide-angle visualization with BIOM as a nonvitrectomy approach for treating peripheral large retinal tears with localized retinal detachment.</p><p><strong>Methods: </strong>A 60-year-old patient presented with a peripheral large retinal tear and localized retinal detachment (RD). Owing to media opacity and far peripheral location, barrier laser could not be completed with conventional laser delivery systems. Because of the potential risk of aggravating RD in the setting of a large retinal break with overlying vitreoretinal traction, external cryotherapy was not used. Instead, we used 25g single-port illuminated endolaser probe to complete the barrier laser photocoagulation around the retinal break and localized RD area with the assistance of scleral indentation using a 150° wide-angle BIOM system without vitrectomy.</p><p><strong>Results: </strong>The single-port illuminated endolaser approach provided enhanced visualization including extreme peripheral location of the retina while depressing the sclera, allowing for comprehensive laser coverage of the lesion. This effectively prevented the progression of RD and facilitated fluid absorption, ultimately leading to the resolution of the localized RD. At 4 months postlaser treatment, the patient's retina is stable with well-formed chorioretinal adhesion.</p><p><strong>Conclusion: </strong>When retinal breaks are located in the far periphery with severe VR traction and media opacity is present, completion of conventional laser treatment may be challenging. A 25 g single-port illuminated endolaser photocoagulation without vitrectomy under BIOM may serve as an effective treatment option.</p>","PeriodicalId":53580,"journal":{"name":"Retinal Cases and Brief Reports","volume":"20 4","pages":"529-532"},"PeriodicalIF":0.0,"publicationDate":"2026-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148310432","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"CHOROIDAL ISCHEMIA IN PATIENTS WITH CATASTROPHIC ANTIPHOSPHOLIPID SYNDROME: A CASE SERIES.","authors":"Melvin Gerardy, Alain Gaudric, Pierre Duraffour, Vanessa Sentis, Francine Behar-Cohen, Nathalie Costedoat Chalumeau, Véronique Le Guern, Nathalie Morel, Vincent Soler, Elodie Bousquet","doi":"10.1097/ICB.0000000000001779","DOIUrl":"10.1097/ICB.0000000000001779","url":null,"abstract":"<p><strong>Purpose: </strong>To report three cases of acute choroidal ischemia in patients diagnosed with catastrophic antiphospholipid syndrome.</p><p><strong>Methods: </strong>The medical and imaging records of patients with catastrophic antiphospholipid syndrome were retrospectively reviewed. Patients underwent retinal imaging, including fundus photography, spectral-domain optical coherence tomography, fluorescein and indocyanine green angiography.</p><p><strong>Results: </strong>This report summarizes three cases of pregnant women (six eyes) with catastrophic antiphospholipid syndrome and posterior ocular involvement. Spectral-domain optical coherence tomography revealed multiple subretinal detachments. Fluorescein and indocyanine green angiography showed triangular nonperfused areas consistent with Amalric triangular choroidal infarction and multiple spots of subretinal leakage. Patients were hospitalized in intensive care unit for treatment with corticosteroids, anticoagulants, and plasma exchanges/intravenous immunoglobulins. Full recovery was observed in all cases.</p><p><strong>Conclusion: </strong>The presence of acute choroidal ischemia in patients with antiphospholipid syndrome should alert ophthalmologists to the possibility of catastrophic antiphospholipid syndrome, which is a life-threatening disease. Patients should immediately be referred to a specialist.</p>","PeriodicalId":53580,"journal":{"name":"Retinal Cases and Brief Reports","volume":" ","pages":"568-574"},"PeriodicalIF":0.0,"publicationDate":"2026-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144531038","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"IMPACT OF NEONATAL FAMILY SCREENING IN EARLY-ONSET MANAGEMENT OF TSPAN 12 POSITIVE FAMILIAL EXUDATIVE VITREORETINOPATHY: A CASE REPORT.","authors":"Manoj P Shettigar, Subhadra Jalali, Komal Agarwal, Akash Belenje","doi":"10.1097/ICB.0000000000001764","DOIUrl":"10.1097/ICB.0000000000001764","url":null,"abstract":"<p><strong>Purpose: </strong>To report a case of familial exudative vitreoretinopathy (FEVR) where both the mother and the daughter had the same genetic mutation in TSPAN 12, and the daughter had treatable retinal detachment at birth.</p><p><strong>Methods: </strong>This is an interventional case report.</p><p><strong>Results: </strong>A 28-year-old primi gravida, a known case of FEVR presented to our OPD in the first trimester. Targeted imaging for fetal anomalies scan ruled out any anomalies. A planned near-term, but early elective delivery was done at the 36th week of gestational age, and the child was brought for early neonatal screening for FEVR at age 10 days. The birth weight was 3.6 kg. Fundus evaluation showed bilateral disc and arcade drag due to a highly vascular temporal peripheral tractional retinal detachment. Diagnosis of bilateral FEVR Stage 3A retinal detachment was made. A bilateral lens-sparing vitrectomy with endolaser was performed to mitigate the traction onto the retina. The child did well postoperatively. Genetic testing of the mother and the child showed the same TSPAN12 (c.738G>A) gene mutation.</p><p><strong>Conclusion: </strong>Surgical success in FEVR can hinge on the timely screening of the new family member. Progression of FEVR to more advanced stages may be prevented with laser photocoagulation and prompt surgery whenever indicated. It is imperative to educate FEVR patients about the risk to the next generation and the importance of good antenatal monitoring, early delivery, and immediate postnatal ophthalmic fundoscopic examination of newborns.</p>","PeriodicalId":53580,"journal":{"name":"Retinal Cases and Brief Reports","volume":" ","pages":"536-539"},"PeriodicalIF":0.0,"publicationDate":"2026-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144057839","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Management of Anteriorly Migrated Fluocinolone 0.18- & 0.19-mg Implants Using Scleral Suture Fixation With and Without Concomitant Implantation of A Fluocinolone 0.59-mg Implant.","authors":"Tiffany C Nguyen, Cynthia K McClard, Christopher D Riemann","doi":"10.1097/ICB.0000000000001856","DOIUrl":"10.1097/ICB.0000000000001856","url":null,"abstract":"<p><strong>Purpose: </strong>To demonstrate two surgical fixation techniques to salvage anteriorly migrated fluocinolone acetonide implants (Yutiq; Alimera Sciences Limited, Alpharetta, GA) (Iluvien; Alimera Sciences Limited, Alpharetta, GA - Both assets were acquired by ANI Pharmaceuticals, Princeton, NJ, since this artical was initially written).</p><p><strong>Methods: </strong>Anteriorly dislocated steroid implant pellets were retrieved and successfully suture-fixated to the pars plana or to a newly implanted 0.59-mg fluocinolone acetonide implant (Retisert; Bausch & Lomb, Rochester, NY) with nonabsorbable suture to securely reposition them into the vitreous compartment.</p><p><strong>Results: </strong>Both presented techniques successfully refixated implants, which remained fixated at long-term follow-up for all patients. All patients tolerated the procedures well with no adverse outcomes or complications from refixation.</p><p><strong>Conclusions: </strong>The presented surgical techniques offer novel and effective methods to manage anteriorly migrated steroid implants.</p>","PeriodicalId":53580,"journal":{"name":"Retinal Cases and Brief Reports","volume":" ","pages":"596-601"},"PeriodicalIF":0.0,"publicationDate":"2026-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145946818","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}