Retinal Cases and Brief Reports最新文献

筛选
英文 中文
INDETERMINATE CELL HISTIOCYTOSIS WITH OCULAR INVOLVEMENT IN A NEONATE: A CASE REPORT. 新生儿眼部受累的不定形细胞组织细胞增生症:病例报告。
Retinal Cases and Brief Reports Pub Date : 2025-03-01 DOI: 10.1097/ICB.0000000000001545
Alexis Kassotis, Lauren Yeager, Dmitry Bogomolny, Brian Marr
{"title":"INDETERMINATE CELL HISTIOCYTOSIS WITH OCULAR INVOLVEMENT IN A NEONATE: A CASE REPORT.","authors":"Alexis Kassotis, Lauren Yeager, Dmitry Bogomolny, Brian Marr","doi":"10.1097/ICB.0000000000001545","DOIUrl":"10.1097/ICB.0000000000001545","url":null,"abstract":"<p><strong>Purpose: </strong>The authors describe a case of Indeterminate cell histiocytosis, a rare disease of histiocytic proliferation on the spectrum of Langerhans cell histiocytosis.</p><p><strong>Methods: </strong>Data were collected through retrospective chart review.</p><p><strong>Results: </strong>The authors present a novel case of congenital Indeterminate cell histiocytosis with multisystem disease, including significant pan-ocular involvement. The neonate was successfully treated with the BRAF-kinase inhibitor dabrafenib, local anti-VEGF, and corticosteroid.</p><p><strong>Conclusions: </strong>The present case expands on the current ocular presentations of Indeterminate cell histiocytosis.</p>","PeriodicalId":53580,"journal":{"name":"Retinal Cases and Brief Reports","volume":" ","pages":"174-176"},"PeriodicalIF":0.0,"publicationDate":"2025-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"139081041","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
AUTOIMMUNE RETINOPATHY IN A PATIENT WITH STIFF-PERSON SYNDROME: A CASE REPORT. 僵人综合征患者的自身免疫性视网膜病变:病例报告。
Retinal Cases and Brief Reports Pub Date : 2025-03-01 DOI: 10.1097/ICB.0000000000001543
Ronak M Shah, Maya H Maloney, Aubrey L Gilbert, Amar P Patel, Robin A Vora
{"title":"AUTOIMMUNE RETINOPATHY IN A PATIENT WITH STIFF-PERSON SYNDROME: A CASE REPORT.","authors":"Ronak M Shah, Maya H Maloney, Aubrey L Gilbert, Amar P Patel, Robin A Vora","doi":"10.1097/ICB.0000000000001543","DOIUrl":"10.1097/ICB.0000000000001543","url":null,"abstract":"<p><strong>Purpose: </strong>The aim of this study was to describe a patient who developed retinal degeneration associated with autoimmune retinopathy and who was also found to have anti-glutamic acid decarboxylase (GAD65) autoantibodies and the diagnosis of stiff-person syndrome.</p><p><strong>Methods: </strong>Ophthalmologic workup consisted of clinical examination, multimodality retinal imaging, and electrophysiologic testing. Further neurologic assessment including relevant serum and cerebrospinal fluid studies was also conducted.</p><p><strong>Results: </strong>We highlight the case of a 45-year-old patient who developed subacute, sequential vision loss, along with bilateral lower extremity weakness. On initial presentation, optical coherence tomography of the left eye was notable for diffuse attenuation of the outer retinal bands. Fundus autofluorescence demonstrated a ring of hyperautofluorescence encircling the fovea of the left eye. At 15-month follow-up, the right eye also became similarly affected. He was found to have elevated serum and cerebrospinal anti-GAD65 autoantibodies and was diagnosed with both stiff-person syndrome and autoimmune retinopathy.</p><p><strong>Conclusion: </strong>There is a potential association of anti-GAD65 autoantibodies with the development of autoimmune retinopathy.</p>","PeriodicalId":53580,"journal":{"name":"Retinal Cases and Brief Reports","volume":" ","pages":"139-144"},"PeriodicalIF":0.0,"publicationDate":"2025-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"138832976","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
SUCCESSFUL TREATMENT OF CANCER-ASSOCIATED RETINOPATHY WITH INTRAVITREAL DEXAMETHASONE IMPLANT FOLLOWED BY A 0.18-MG FLUOCINOLONE IMPLANT WITHOUT SYSTEMIC IMMUNOSUPPRESSION. 在不使用全身免疫抑制剂的情况下,使用玻璃体内地塞米松植入剂和 0.18 毫克氟西诺龙植入剂成功治疗临床诊断的癌症相关视网膜病变。
Retinal Cases and Brief Reports Pub Date : 2025-03-01 DOI: 10.1097/ICB.0000000000001552
Lingling Huang, Paul Yang, Christina Flaxel, Eric Suhler, Phoebe Lin
{"title":"SUCCESSFUL TREATMENT OF CANCER-ASSOCIATED RETINOPATHY WITH INTRAVITREAL DEXAMETHASONE IMPLANT FOLLOWED BY A 0.18-MG FLUOCINOLONE IMPLANT WITHOUT SYSTEMIC IMMUNOSUPPRESSION.","authors":"Lingling Huang, Paul Yang, Christina Flaxel, Eric Suhler, Phoebe Lin","doi":"10.1097/ICB.0000000000001552","DOIUrl":"10.1097/ICB.0000000000001552","url":null,"abstract":"<p><strong>Purpose: </strong>The aim of the study was to report a case of clinically diagnosed cancer-associated retinopathy successfully treated with intravitreal corticosteroid implants without systemic immunosuppression.</p><p><strong>Methods: </strong>This was a case report with multimodal imaging.</p><p><strong>Results: </strong>An 80-year-old man without known systemic malignancy presented with debilitating shimmering, hemeralopia, and rapidly progressive bilateral vision loss following uncomplicated cataract surgery. Mild vitritis, extensive photoreceptor loss, mottling of retinal pigment epithelium, and mild vascular attenuation were found in both eyes. Full-field electroretinogram showed severe bilateral rod-cone dysfunction. Infectious etiologies and vitreoretinal lymphoma were ruled out. During cancer workup, intravitreal corticosteroid treatment was offered. Significant anatomical improvement with reconstitution of the ellipsoid zone, improved retinal pigment epithelium irregularities, and functional improvement were observed 3 weeks after bilateral intravitreal dexamethasone implants (Ozurdex). After 2 months, the patient received bilateral intravitreal 0.18-mg fluocinolone acetonide implants (YUTIQ). Later, a colonic adenocarcinoma was found (pathologic stage pT3 pN0). The patient recovered well from surgery, and no chemotherapy was needed. Nine months since bilateral intravitreal fluocinolone acetonide implants (11 months since bilateral intravitreal dexamethasone implants), best-corrected vision maintained at 20/25-2 in the right eye and 20/20 in the left eye without ongoing treatments. Bilateral reconstitution of ellipsoid zones and near resolution of retinal pigment epithelium irregularities remained stable. Repeat full-field electroretinogram demonstrated improved cone response in the left eye and stable diminished rod response in both eyes. The patient reported resolution of ocular symptoms.</p><p><strong>Conclusion: </strong>The sustained improvements with intravitreal corticosteroid monotherapy suggest potential advantages using local therapy over systemic treatment. A long-term follow-up is warranted. Further research is needed to evaluate the efficacy of using the 0.18-mg fluocinolone implant (YUTIQ) to treat cancer-associated retinopathy.</p>","PeriodicalId":53580,"journal":{"name":"Retinal Cases and Brief Reports","volume":" ","pages":"214-220"},"PeriodicalIF":0.0,"publicationDate":"2025-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"139934195","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
THE ROLE OF OPTICAL COHERENCE TOMOGRAPHY ANGIOGRAPHY IN DOME-SHAPED MACULOPATHY. 光学相干断层血管造影在穹隆状黄斑病变中的作用。
Retinal Cases and Brief Reports Pub Date : 2025-03-01 DOI: 10.1097/ICB.0000000000001530
Daniel Milad, Fares Antaki, Andrea Dahoud, Andrew Farah, Karim Hammamji, Marc Saab
{"title":"THE ROLE OF OPTICAL COHERENCE TOMOGRAPHY ANGIOGRAPHY IN DOME-SHAPED MACULOPATHY.","authors":"Daniel Milad, Fares Antaki, Andrea Dahoud, Andrew Farah, Karim Hammamji, Marc Saab","doi":"10.1097/ICB.0000000000001530","DOIUrl":"10.1097/ICB.0000000000001530","url":null,"abstract":"<p><strong>Purpose: </strong>The aim of this study was to demonstrate the role of optical coherence tomography angiography in the management of dome-shaped maculopathy.</p><p><strong>Methods: </strong>This was a retrospective case review.</p><p><strong>Results: </strong>A 52-year-old woman was referred to the authors' retinal service for potential bilateral choroidal neovascular membrane (CNVM) and blurry vision bilaterally. Initial spectacle-corrected visual acuity was 20/30-2 in the right eye and 20/30 + 2 in the left eye. Dome-shaped maculopathy was diagnosed on optical coherence tomography. In both eyes, optical coherence tomography B-scan passing through the fovea showed shallow irregular retinal pigment epithelium elevation suspicious of occult (type 1) CNVM. The outer retinal and choriocapillaris angiograms showed a zone of nonexudative CNVM in the right eye and exudative CNVM in the left eye. Given the persistent subretinal fluid with CNVM in the left eye, the authors elected to perform intravitreal injections of ranibizumab 0.5 mg on a treat and extend regimen. On the most recent follow-up, the best-corrected visual acuity improved to 20/20 in the left eye with no persisting subretinal fluid.</p><p><strong>Conclusion: </strong>The authors present a case where assessing disease progression and the development of CNVM and evaluating the efficiency of therapies were realized through the application of novel optical coherence tomography angiography technology. This diagnostic tool may be used to guide clinicians in their management of dome-shaped maculopathy, as demonstrated through the authors' experience. Optical coherence tomography angiography can also make it possible to visualize nonexudative CNVM lesions that may be missed on traditional imaging assessments.</p>","PeriodicalId":53580,"journal":{"name":"Retinal Cases and Brief Reports","volume":" ","pages":"248-252"},"PeriodicalIF":0.0,"publicationDate":"2025-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"138804484","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
INTRAVITREAL FARICIMAB AS AN ADJUVANT IN THE MANAGEMENT OF TUBERCULAR UVEITIS. 将玻璃体内法尼单抗作为治疗结核性葡萄膜炎的辅助药物。
Retinal Cases and Brief Reports Pub Date : 2025-03-01 DOI: 10.1097/ICB.0000000000001542
Yasmine Alcibahy, Karina Julian, Maria Fernanda Bonilla, Ali Mohamed, Sarah Amrani, Aniruddha Agarwal
{"title":"INTRAVITREAL FARICIMAB AS AN ADJUVANT IN THE MANAGEMENT OF TUBERCULAR UVEITIS.","authors":"Yasmine Alcibahy, Karina Julian, Maria Fernanda Bonilla, Ali Mohamed, Sarah Amrani, Aniruddha Agarwal","doi":"10.1097/ICB.0000000000001542","DOIUrl":"10.1097/ICB.0000000000001542","url":null,"abstract":"<p><strong>Purpose: </strong>The objective of this study was to report the use of intravitreal faricimab used as an adjunct in the management of intraocular tuberculosis in a patient with occlusive retinal vasculitis and choroiditis.</p><p><strong>Methods: </strong>This is a case report.</p><p><strong>Results: </strong>A 27-year-old Asian man presented with bilateral choroiditis and occlusive retinal vasculitis complicated by retinal neovascularization and vitreous hemorrhage in one eye. The patient had a positive tuberculin skin test, indeterminate interferon-gamma release assay, and Ghon focus on chest radiography. With a diagnosis of intraocular tuberculosis, the patient was treated with antitubercular therapy. Owing to the significant vitreous hemorrhage, he underwent pars plana vitrectomy in one eye. The patient received bilateral faricimab. Within a week of the injection, he had a near-complete resolution of the extensive choroidal and retinal vascular inflammation.</p><p><strong>Conclusion: </strong>Intravitreal faricimab, given its angiopoietin-2 inhibition and antivascular endothelial growth factor action, maybe a helpful adjunct in intraocular tuberculosis. Whether angiopoietin-2 inhibition provides any additional benefit needs further evaluation in extensive studies.</p>","PeriodicalId":53580,"journal":{"name":"Retinal Cases and Brief Reports","volume":" ","pages":"177-181"},"PeriodicalIF":0.0,"publicationDate":"2025-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"138832977","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
DISAPPEARING CHOROIDAL MASS: OPHTHALMIC MANIFESTATIONS OF A PRESUMED KIKUCHI-FUJIMOTO DISEASE. 消失的脉络膜肿块:推测为菊地-藤本氏病的眼部表现。
Retinal Cases and Brief Reports Pub Date : 2025-03-01 DOI: 10.1097/ICB.0000000000001544
Selene Rodríguez-Castro, Jans Fromow-Guerra, Salvador Garza-González, Angela Pinilla-Monroy, Vidal Soberon
{"title":"DISAPPEARING CHOROIDAL MASS: OPHTHALMIC MANIFESTATIONS OF A PRESUMED KIKUCHI-FUJIMOTO DISEASE.","authors":"Selene Rodríguez-Castro, Jans Fromow-Guerra, Salvador Garza-González, Angela Pinilla-Monroy, Vidal Soberon","doi":"10.1097/ICB.0000000000001544","DOIUrl":"10.1097/ICB.0000000000001544","url":null,"abstract":"<p><strong>Purpose: </strong>To report our findings in a patient with presumed Kikuchi-Fujimoto disease.</p><p><strong>Methods: </strong>Report of clinical findings, fundus images, optical coherence tomography, and ultrasonography.</p><p><strong>Results: </strong>A 19-year-old female patient who presented with an unusual form of symptoms that fit a disease called Kikuchi-Fujimoto disease. A large choroidal mass was observed in the posterior pole; a month later, the mass was completely gone.</p><p><strong>Conclusion: </strong>Large choroidal masses can occur in patients with Kikuchi-Fujimoto disease, and these do not warrant treatment as they are self-limiting.</p>","PeriodicalId":53580,"journal":{"name":"Retinal Cases and Brief Reports","volume":" ","pages":"228-231"},"PeriodicalIF":0.0,"publicationDate":"2025-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"139485873","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
SWEEPING TECHNIQUE FOR THE REMOVAL OF EMULSIFIED SILICONE OIL DROPLETS FROM THE ANTERIOR SURFACE OF THE IRIS USING AN OPHTHALMIC ABSORPTION SPONGE. 使用眼科吸收海绵清除虹膜前表面乳化硅油滴的清扫技术。
Retinal Cases and Brief Reports Pub Date : 2025-03-01 DOI: 10.1097/ICB.0000000000001539
Tomoki Kurihara, Chiharu Iwahashi, Fukutaro Mano, Shunji Kusaka
{"title":"SWEEPING TECHNIQUE FOR THE REMOVAL OF EMULSIFIED SILICONE OIL DROPLETS FROM THE ANTERIOR SURFACE OF THE IRIS USING AN OPHTHALMIC ABSORPTION SPONGE.","authors":"Tomoki Kurihara, Chiharu Iwahashi, Fukutaro Mano, Shunji Kusaka","doi":"10.1097/ICB.0000000000001539","DOIUrl":"10.1097/ICB.0000000000001539","url":null,"abstract":"<p><strong>Purpose: </strong>Silicone oil (SO) tamponade is frequently used in complex vitreoretinal surgeries, and SO migration into the anterior chamber can lead to complications, such as glaucoma and corneal decompensation. A new technique is described for the efficient removal of emulsified SO droplets, which can adhere strongly to the anterior surface of the iris.</p><p><strong>Methods: </strong>The tip of an ophthalmic absorption sponge was cut to an approximately 1 mm × 1 mm size. Using forceps, the sponge was inserted through a 25-gauge trocar and then through a corneal paracentesis to gently scrape the surface of the iris to dislodge the adherent SO droplets, which were subsequently aspirated.</p><p><strong>Results: </strong>This technique efficiently and effectively dislodged and mobilized most emulsified SO droplets, thereby allowing removal through aspiration using a vitrector. Two months after surgery, the retina remained attached, the intraocular pressure decreased from 18 mm Hg to 15 mm Hg, and there were no visible SO droplets in the anterior chamber.</p><p><strong>Conclusion: </strong>The sweeping technique is a safe and efficient method to dislodge, mobilize, and aspirate emulsified SO droplets that are adherent to the anterior surface of the iris, thereby decreasing the risk of future SO-related complications.</p>","PeriodicalId":53580,"journal":{"name":"Retinal Cases and Brief Reports","volume":" ","pages":"283-285"},"PeriodicalIF":0.0,"publicationDate":"2025-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"139040901","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
RETINAL PHAKOMATOSIS AND VON HIPPEL-LINDAU PERIPHERAL CAPILLARY HEMANGIOBLASTOMA: PROPOSAL FOR STAGED SURGERY. 视网膜法孔症和 Von Hippel-Lindau 周围毛细血管血管母细胞瘤:分期手术建议。
Retinal Cases and Brief Reports Pub Date : 2025-03-01 DOI: 10.1097/ICB.0000000000001550
Carla E Gallenga, Lucia Zeppa, Ilaria De Pascale, Giulio Salerno, Paolo Tassinari, Paolo Perri, Lucio Zeppa
{"title":"RETINAL PHAKOMATOSIS AND VON HIPPEL-LINDAU PERIPHERAL CAPILLARY HEMANGIOBLASTOMA: PROPOSAL FOR STAGED SURGERY.","authors":"Carla E Gallenga, Lucia Zeppa, Ilaria De Pascale, Giulio Salerno, Paolo Tassinari, Paolo Perri, Lucio Zeppa","doi":"10.1097/ICB.0000000000001550","DOIUrl":"10.1097/ICB.0000000000001550","url":null,"abstract":"<p><strong>Purpose: </strong>Retinal capillary hemangioblastoma is present in about half of the carriers of the von Hippel-Lindau gene mutation and can lead to the evolution of blindness. Herewith is a proposal for surgical intraretinal feeder vessel ligature to induce ischemia of the phakoma and to resolve the exudative secondary retinal detachment, with satisfying results at the 6-month follow-up endpoint.</p><p><strong>Methods: </strong>The patient underwent a chandelier-assisted 23-gauge pars plana vitrectomy with valved trocars. A bimanual transretinal ligature of the feeder vessel of hemangioblastoma was performed, followed by localized endolaser to ablate the surrounding retina and capillaries, and a polydimethylsiloxane 1,000 final tamponade. After 3 months, exchange of polydimethylsiloxane/air/balanced salt solution, phacoemulsification, and in-the-bag intraocular lens implantation were performed.</p><p><strong>Results: </strong>At the sixth month, fundus fluorescein angiography showed a significant reduction of blood flow in the phakoma. The final best-corrected visual acuity was 6/6 (9 lines gain obtained compared with the baseline time).</p><p><strong>Conclusion: </strong>This surgical technique seems to be effective and promising for the treatment of von Hippel-Lindau retinal capillary hemangioblastomas and their related retinal complications.</p>","PeriodicalId":53580,"journal":{"name":"Retinal Cases and Brief Reports","volume":" ","pages":"205-209"},"PeriodicalIF":0.0,"publicationDate":"2025-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"139106812","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
POTASSIUM IODATE RETINOTOXICITY AFTER AN OVERDOSE OF ANTIRADIATION PILLS: A CASE OF APOCALYPTIC RETINOPATHY. 过量服用抗辐射药片后的碘酸钾视网膜毒性:一个世界末日视网膜病变的病例。
Retinal Cases and Brief Reports Pub Date : 2025-03-01 DOI: 10.1097/ICB.0000000000001548
Paul S Bernstein
{"title":"POTASSIUM IODATE RETINOTOXICITY AFTER AN OVERDOSE OF ANTIRADIATION PILLS: A CASE OF APOCALYPTIC RETINOPATHY.","authors":"Paul S Bernstein","doi":"10.1097/ICB.0000000000001548","DOIUrl":"10.1097/ICB.0000000000001548","url":null,"abstract":"<p><strong>Purpose: </strong>The aim of this study was to report a case of severe retinal toxicity after an attempted suicidal overdose of antiradiation pills containing a well-known retinal pigment epithelial toxin, potassium iodate.</p><p><strong>Methods: </strong>Clinical examination and multimodal imaging are provided from a clinic visit 11 years after the suicide attempt.</p><p><strong>Results: </strong>A 42-year-old patient had widespread retinal atrophy in both eyes with near-complete absence of the retinal pigment epithelium and severe retinal thinning. A few remaining areas of preserved photoreceptors provided her with 20/60 and 20/200 vision in her right and left eyes, respectively, with very constricted visual fields.</p><p><strong>Conclusion: </strong>Despite being first described over 100 years ago, few cases of iodate retinotoxicity have been reported in the published literature, and most are related to accidental or intentional ingestion of iodate salts used to iodize table salt. This unique case of iodate retinotoxicity secondary to antiradiation tablets highlights the risks of unregulated sale of these agents marketed in the United States as essential components of nuclear apocalypse \"go bags\" because they have a poor margin of safety and no specific warnings of the risk of permanent blindness with overdosage.</p>","PeriodicalId":53580,"journal":{"name":"Retinal Cases and Brief Reports","volume":"19 2","pages":"145-147"},"PeriodicalIF":0.0,"publicationDate":"2025-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11217146/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143505950","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
IDENTIFICATION OF CHOROIDAL VASCULAR ABNORMALITIES IN PATIENTS WITH HEREDITARY HEMORRHAGIC TELANGIECTASIA. 遗传性出血性远端血管扩张症(HHT)患者脉络膜血管异常的鉴定。
Retinal Cases and Brief Reports Pub Date : 2025-03-01 DOI: 10.1097/ICB.0000000000001532
Hanna N Luong, Odette M Houghton
{"title":"IDENTIFICATION OF CHOROIDAL VASCULAR ABNORMALITIES IN PATIENTS WITH HEREDITARY HEMORRHAGIC TELANGIECTASIA.","authors":"Hanna N Luong, Odette M Houghton","doi":"10.1097/ICB.0000000000001532","DOIUrl":"10.1097/ICB.0000000000001532","url":null,"abstract":"<p><strong>Purpose: </strong>The aim of this study was to evaluate the frequency of ocular imaging in patients with hereditary hemorrhagic telangiectasia (HHT) at a large academic medical institution, characterize the choroidal vascular changes on indocyanine green angiography and optical coherence tomography, and explore the relationship of these ocular features with HHT genotypes and systemic manifestations.</p><p><strong>Methods: </strong>This is a retrospective review of patients with HHT who were seen in the Mayo Clinic ophthalmology department between 2011 and 2021.</p><p><strong>Results: </strong>Of the 71 patients with HHT identified, 7 patients (10%) had qualifying imaging defined as radial or raster spectral-domain optical coherence tomography scans and/or indocyanine green angiography. Four patients (57%) had enlarged choroidal vessels detected on optical coherence tomography and/or indocyanine green angiography. Three patients (43%) had retinal telangiectasias. Patients with choroidal changes (mean age 67 years) had the endoglin gene mutation, gastrointestinal arteriovenous malformations, and facial and mucocutaneous telangiectasias. By contrast, patients without choroidal changes (mean age 45 years) included the activin A receptor-like kinase 1 gene mutation.</p><p><strong>Conclusion: </strong>Only a small proportion of patients with HHT undergo ophthalmic imaging at the authors' institution. The presence of choroidal abnormalities is associated with the endoglin gene mutation, older age, corroborating retinal vascular changes, and increased systemic manifestations.</p>","PeriodicalId":53580,"journal":{"name":"Retinal Cases and Brief Reports","volume":" ","pages":"232-235"},"PeriodicalIF":0.0,"publicationDate":"2025-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"138802108","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
0
×
引用
GB/T 7714-2015
复制
MLA
复制
APA
复制
导出至
BibTeX EndNote RefMan NoteFirst NoteExpress
×
提示
您的信息不完整,为了账户安全,请先补充。
现在去补充
×
提示
您因"违规操作"
具体请查看互助需知
我知道了
×
提示
确定
请完成安全验证×
相关产品
×
本文献相关产品
联系我们:info@booksci.cn Book学术提供免费学术资源搜索服务,方便国内外学者检索中英文文献。致力于提供最便捷和优质的服务体验。 Copyright © 2023 布克学术 All rights reserved.
京ICP备2023020795号-1
ghs 京公网安备 11010802042870号
Book学术文献互助
Book学术文献互助群
群 号:481959085
Book学术官方微信