Retinal Cases and Brief Reports最新文献_第7页

OPTICAL COHERENCE TOMOGRAPHY INTERFACE REFLECTION IMAGE ASSOCIATED WITH INTRAVITREAL GAS. 与玻璃体内气体相关的光学相干层析成像界面反射图像。

Retinal Cases and Brief Reports Pub Date : 2026-07-01 DOI: 10.1097/ICB.0000000000001770

Michael Colucciello

引用次数: 0

RETINAL TOXICITY ASSOCIATED WITH NAB-PACLITAXEL AND GEMCITABINE WITH SBP-101. nab -紫杉醇和吉西他滨联合SBP-101的视网膜毒性。

Retinal Cases and Brief Reports Pub Date : 2026-07-01 DOI: 10.1097/ICB.0000000000001767

Ashley Z Zhou, Jin Kyun Oh, Stephen H Tsang, Jason D Horowitz, Vlad Diaconita

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HOME OPTICAL COHERENCE TOMOGRAPHY-GUIDED MANAGEMENT OF TYPE 3 MACULAR NEOVASCULARIZATION. 家用光学相干层析成像引导下治疗3型黄斑新生血管。

Retinal Cases and Brief Reports Pub Date : 2026-07-01 DOI: 10.1097/ICB.0000000000001792

Livia Faes, Nancy Holekamp, Gidi Benyamini, Kester Nahen, Nishant Mohan, K Bailey Freund

{"title":"HOME OPTICAL COHERENCE TOMOGRAPHY-GUIDED MANAGEMENT OF TYPE 3 MACULAR NEOVASCULARIZATION.","authors":"Livia Faes, Nancy Holekamp, Gidi Benyamini, Kester Nahen, Nishant Mohan, K Bailey Freund","doi":"10.1097/ICB.0000000000001792","DOIUrl":"10.1097/ICB.0000000000001792","url":null,"abstract":"Purpose: To explore the impact of home optical coherence tomography (OCT)-guided treatment personalization for type 3 macular neovascularization in age-related macular degeneration.Methods: A prospective home OCT trial of a patient with a 1-month history of type 3 macular neovascularization under antiangiogenic treatment (2 \"loading\" injections). During the 23.4-week study period, the patient's treatment regimen was managed through regular self-imaging, enabling continuous monitoring of retinal fluid dynamics.Results: During the observation period, the patient performed 143 home OCT measurements (mean 6.1 per week, SD 1), which prompted 3 in-office visits where 3 antiangiogenic injections were delivered at the discretion of the investigator. The mean individualized treatment intervals established through home OCT were 8 weeks, with the patient maintaining stable visual acuity at 20/20 Snellen. Complete resolution of intraretinal fluid was noted between injections. Notably, home OCT revealed unexpected fluctuations in retinal fluid measured as hyporeflective spaces in the absence of treatment. Two out of 3 injections were administered after the retinal fluid volume had decreased by more than half within 2 and 8 days after an initial transient spike.Conclusion: The neovascular subtype as defined by the Consensus Nomenclature for Reporting Neovascular AMD Data may serve as a useful management framework when approaching home OCT-guided treatment decisions. In type 3 disease, home OCT-guided management demonstrates significant potential for optimizing treatment. Further research is warranted to elucidate the dynamics of retinal fluid variations in different macular neovascularization subtypes.","PeriodicalId":53580,"journal":{"name":"Retinal Cases and Brief Reports","volume":" ","pages":"515-522"},"PeriodicalIF":0.0,"publicationDate":"2026-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144700281","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

SPONTANEOUS RESOLUTION OF PTOSIS AFTER SCLERAL BUCKLING. 巩膜屈曲后上睑下垂的自发消退。

Retinal Cases and Brief Reports Pub Date : 2026-07-01 DOI: 10.1097/ICB.0000000000001786

Justin C Muste, Catherine J Hwang, Joseph Abraham, Devon A Cohen, Sumit Sharma

引用次数: 0

Endogenous Streptococcus Anginosus Endophthalmitis: A Case Report and Review of the Literature. 内源性心绞痛链球菌眼内炎1例并文献复习。

Retinal Cases and Brief Reports Pub Date : 2026-06-25 DOI: 10.1097/ICB.0000000000001908

Nish Patel, Tejaswini Matsyaraja, Marten R Hawkins, Shilpa Kodati

{"title":"Endogenous Streptococcus Anginosus Endophthalmitis: A Case Report and Review of the Literature.","authors":"Nish Patel, Tejaswini Matsyaraja, Marten R Hawkins, Shilpa Kodati","doi":"10.1097/ICB.0000000000001908","DOIUrl":"10.1097/ICB.0000000000001908","url":null,"abstract":"Purpose: To report a case of unilateral endogenous Streptococcus anginosus endophthalmitis in order to improve timely recognition and treatment strategies for similar presentations.Methods: A retrospective review of the electronic medical record of one patient was performed from September 2024 through December 2024.Results: A 50-year-old healthy male presented with a unilateral hypopyon and dense vitreous opacities. The patient was found to have evidence of systemic infection and endophthalmitis secondary to S. anginosus; specifically, the patient was found to have a large subcarinal mass as well as abscesses in the left cerebrum, both of which were positive for S. anginosus. The patient underwent treatment with intravitreal and systemic antibiotics as well as pars plana vitrectomy.Conclusion: S. anginosus endophthalmitis in the setting of a confirmed primary mediastinal infection has not previously been reported. Our patient had a particularly virulent presentation of S. anginosus endophthalmitis, and the ophthalmic findings led to the diagnosis of a systemic infection. A thorough systemic evaluation of patients with suspected endogenous endophthalmitis should be pursued, and a seemingly noncontributory medical history can prove to be significant.","PeriodicalId":53580,"journal":{"name":"Retinal Cases and Brief Reports","volume":" ","pages":""},"PeriodicalIF":0.0,"publicationDate":"2026-06-25","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148320689","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Kenny-Caffey syndrome: nanophthalmos complicated by uveal effusion, presentation and treatment. 肯尼-卡菲综合征：纳米眼并发葡萄膜积液，表现和治疗。

Retinal Cases and Brief Reports Pub Date : 2026-06-23 DOI: 10.1097/ICB.0000000000001950

Alessandra Romano, Carlo Bellucci, Antonio De Santis, Elio Spaggiari, Paolo Mora

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Cancer-Associated Retinopathy Worsening After Tumor Resection: Case Report and Review of the Literature. 肿瘤切除后癌症相关视网膜病变恶化：病例报告及文献回顾。

Retinal Cases and Brief Reports Pub Date : 2026-06-23 DOI: 10.1097/ICB.0000000000001948

Melissa M Warne, Pawan Bhatnagar, Matthew M Habib

{"title":"Cancer-Associated Retinopathy Worsening After Tumor Resection: Case Report and Review of the Literature.","authors":"Melissa M Warne, Pawan Bhatnagar, Matthew M Habib","doi":"10.1097/ICB.0000000000001948","DOIUrl":"10.1097/ICB.0000000000001948","url":null,"abstract":"Purpose: To report an unusual presentation of cancer associated retinopathy and review the current literature for diagnostic consensus and recommended management.Methods: A single case report of a patient with cancer associated retinopathy that presented as bilateral severe anterior and intermediate uveitis that initially improved with high-dose steroids and IVIG. The patient was assessed via serum laboratory testing, optical coherence tomography, fundus auto-fluorescence, magnetic resonance imaging, lumbar puncture, computed tomography, and Humphrey visual field testing. A targeted literature review was conducted to evaluate visual outcomes in cancer-associated retinopathy (CAR) following tumor-directed therapy by searching Google Scholar from 2022 through April 2026. Studies reporting visual outcomes after tumor resection were included.Results: The patient initially greatly improved after initiation of IV methylprednisolone and IVIG and was stable for four months, but after the patient stopped IVIG due to insurance issues and was tapered off steroids, her vision acutely worsened after undergoing extensive resection of her pelvic mass.Conclusion: Though tumor resection is paramount to patient survival, it may negatively impact the course of cancer-associated retinopathy, particularly in the setting of withdrawal of immunosuppressive therapy. A review of the literature demonstrates heterogeneous visual outcomes following tumor removal, emphasizing the need for careful perioperative management.","PeriodicalId":53580,"journal":{"name":"Retinal Cases and Brief Reports","volume":" ","pages":""},"PeriodicalIF":0.0,"publicationDate":"2026-06-23","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148297299","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Spontaneous Branch Retinal Artery Occlusion Secondary to Aneurysmal Fibrosis in an Adult with Coats Disease: A Case Report. 成人Coats病继发于动脉瘤纤维化的自发性视网膜分支动脉闭塞1例报告。

Retinal Cases and Brief Reports Pub Date : 2026-06-23 DOI: 10.1097/ICB.0000000000001953

Nemer Sayed Ahmad, Adiel Barak, Eric Nudleman, Dinah Zur

{"title":"Spontaneous Branch Retinal Artery Occlusion Secondary to Aneurysmal Fibrosis in an Adult with Coats Disease: A Case Report.","authors":"Nemer Sayed Ahmad, Adiel Barak, Eric Nudleman, Dinah Zur","doi":"10.1097/ICB.0000000000001953","DOIUrl":"10.1097/ICB.0000000000001953","url":null,"abstract":"Purpose: To describe a case of branch retinal artery occlusion (BRAO) in an adult with Coats disease, documented using ultra-widefield fluorescein angiography (UW-FA).Methods: Observational case report with longitudinal evaluation using optical coherence tomography (OCT) and ultra-widefield fluorescein angiography.Results: A 21-year-old male with a childhood diagnosis of Coats disease presented with recalcitrant macular edema and best-corrected visual acuity (BCVA) of 6/40 in the right eye. Baseline UW-FA demonstrated multiple microaneurysms and a patent, tortuous temporal arteriole with focal aneurysmal distention. At a 10-month follow-up, the patient's BCVA remained entirely unchanged. However, repeated UW-FA revealed a new extensive area of retinal nonperfusion extending from the temporal macula to the periphery. Comparison with baseline imaging identified that the previously patent arteriole had become completely occluded at the site of the proximal aneurysm. The absence of prior laser application at this specific site confirms that the subsequent fibrotic closure and arterial occlusion were entirely spontaneous.Conclusion: Sudden arterial occlusion may occur in adult Coats disease due to spontaneous aneurysmal fibrosis. This highlights a vascular remodeling pathway distinct from classic exudative progression. Ultra-widefield imaging may aid in detecting and monitoring these ischemic changes.","PeriodicalId":53580,"journal":{"name":"Retinal Cases and Brief Reports","volume":" ","pages":""},"PeriodicalIF":0.0,"publicationDate":"2026-06-23","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148297282","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Bilateral Giant Pigment Epithelial Detachments and Unilateral RPE Tear and Exudative Retinal Detachment After Tadalafil Exposure: Case Report and Review of the Literature. 他达拉非暴露后双侧巨大色素上皮脱离和单侧RPE撕裂及渗出性视网膜脱离：病例报告及文献回顾。

Retinal Cases and Brief Reports Pub Date : 2026-06-23 DOI: 10.1097/ICB.0000000000001947

Catarina Xavier, Adelaïde Toutée, Thomas Sales de Gauzy, Francesc March de Ribot, Pierre-Antoine Forte, Bahram Bodaghi, Elodie Bousquet, Sara Touhami

{"title":"Bilateral Giant Pigment Epithelial Detachments and Unilateral RPE Tear and Exudative Retinal Detachment After Tadalafil Exposure: Case Report and Review of the Literature.","authors":"Catarina Xavier, Adelaïde Toutée, Thomas Sales de Gauzy, Francesc March de Ribot, Pierre-Antoine Forte, Bahram Bodaghi, Elodie Bousquet, Sara Touhami","doi":"10.1097/ICB.0000000000001947","DOIUrl":"10.1097/ICB.0000000000001947","url":null,"abstract":"Purpose: To describe a case of bilateral giant pigment epithelial detachments (PEDs) complicated by unilateral giant retinal pigment epithelium (RPE) tear and macula-off exudative retinal detachment (RD) in the context of tadalafil exposure, and to place it in the spectrum of reported non-AMD giant RPE tears.Methods: Case report with multimodal imaging and comprehensive systemic work-up, combined with a focused literature review of exudative RD associated with giant RPE tears unrelated to age-related macular degeneration.Results: A 62-year-old man presented with blurred vision in the left eye. Examination revealed bilateral giant temporal PEDs and, in the left eye, a crescent-shaped giant RPE tear contiguous with an inferior macula-off exudative RD and bilateral pachychoroid on OCT. Extensive systemic and ocular investigations were unremarkable except for regular tadalafil use. Discontinuation of tadalafil led to rapid resolution of subretinal fluid and improvement of BCVA to 20/25 OS at one year, whereas re-exposure triggered recurrence of serous macular detachment. Using the Naranjo scale, the causal relationship between tadalafil and the ocular event was rated as \"certain\". Literature review identified 33 published patients (43 eyes) with exudative RD and giant RPE tears without AMD, most commonly associated with bullous CSC and other pachychoroid entities.Conclusion: Bilateral giant PEDs with unilateral giant RPE tear and macula-off exudative RD can occur in the setting of tadalafil-associated bullous CSC. This case underscores the importance of systematically reviewing systemic medications, including phosphodiesterase-5 inhibitors, in patients with atypical serous retinal detachments and RPE tears.","PeriodicalId":53580,"journal":{"name":"Retinal Cases and Brief Reports","volume":" ","pages":""},"PeriodicalIF":0.0,"publicationDate":"2026-06-23","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148297357","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Bilateral panuveitis associated with letrozole therapy. 双侧全葡萄膜炎与来曲唑治疗相关。

Retinal Cases and Brief Reports Pub Date : 2026-06-23 DOI: 10.1097/ICB.0000000000001952

Brian T Cheng, Justin C Muste, Sidra Zafar, Mak B Djulbegovic, Eric D Kim, Flavius A Beca, James P Dunn, Sunir J Garg, Jordan D Deaner

{"title":"Bilateral panuveitis associated with letrozole therapy.","authors":"Brian T Cheng, Justin C Muste, Sidra Zafar, Mak B Djulbegovic, Eric D Kim, Flavius A Beca, James P Dunn, Sunir J Garg, Jordan D Deaner","doi":"10.1097/ICB.0000000000001952","DOIUrl":"10.1097/ICB.0000000000001952","url":null,"abstract":"Purpose: Letrozole is a non-steroidal aromatase inhibitor commonly used for the treatment of postmenopausal estrogen receptor-positive breast cancer. We report a novel case of bilateral panuveitis associated with letrozole therapy.Methods: Retrospective chart review.Results: A 39-year-old female with a history of breast cancer presented with bilateral anterior chamber and vitreous inflammation, perivenular sheathing, retinal hemorrhages, and a focal area of retinal whitening in the left eye six weeks after starting letrozole therapy. Extensive infectious and systemic inflammatory work-up was negative. With letrozole cessation and corticosteroid therapy, the inflammation resolved, and the visual acuity improved to 20/20 bilaterally.Discussion and conclusion: Letrozole-associated panuveitis has not previously been reported. This case highlights the importance of detailed medication history as well as the need for interdisciplinary collaboration when managing drug-induced uveitis. Early recognition and appropriate therapy can result in favorable visual outcomes.","PeriodicalId":53580,"journal":{"name":"Retinal Cases and Brief Reports","volume":" ","pages":""},"PeriodicalIF":0.0,"publicationDate":"2026-06-23","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148297308","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0