International Journal of High Risk Behaviors and Addiction最新文献

{"title":"Evaluation of Salivary Lipid Peroxidation in Paan Users","authors":"L. Farhad-Mollashahi, Z. Dalirsani, A. Nakhaee, Vahid Sahraie","doi":"10.5812/ijhrba-123907","DOIUrl":"https://doi.org/10.5812/ijhrba-123907","url":null,"abstract":"Background: One known risk factor for oral cancer is chewing smokeless tobacco, which is common in southeastern Iran. Smokeless tobacco-related oral complications can be evaluated by assessing parameters of oxidative stress. Objectives: This study evaluated salivary malondialdehyde (MDA) levels in paan users and compared them with nonusers. Patients and Methods: In this study, saliva was collected from 50 paan users and 50 nonusers referred to the Zahedan Dental School in Zahedan, Iran. Salivary MDA was assessed based on standard biochemical methods, and the data were analyzed using a t-test and analysis of variance. Results: In the paan users and the controls, the mean MDA was 2.19 ± 1.05 and 1.24 ± 0.62 (nmol/mL), respectively, and both groups showed significant differences (P < 0.001). The daily consumption and duration were significantly correlated with the MDA concentration, respectively (r = 0.722, P < 0.001), (r = 0.764, P < 0.001). Conclusions: In paan users, salivary MDA concentrations were higher. The concentration of salivary MDA increased with the consumption of paan in more significant quantities and for a more extended time.","PeriodicalId":53452,"journal":{"name":"International Journal of High Risk Behaviors and Addiction","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2022-07-19","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"83680139","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"The First 1000 Days of Life and the Risk of Future Drug Consumption","authors":"S. Mirzaei, N. Oroomiei, N. Nakhaee","doi":"10.5812/ijhrba-123294","DOIUrl":"https://doi.org/10.5812/ijhrba-123294","url":null,"abstract":"Context: The first 1000 days of life last from the beginning of pregnancy to the age of two, a unique step that shapes the basis for a person’s health over their lifetime. Numerous studies have indicated the relationship between one’s first 1000 days of life and the consequent adverse outcomes in adulthood. However, to the extent that we have reviewed it, not a single study has shown the relationship between various aspects of an individual’s first 1000 days of life and the probability of drug consumption in adult life. Hence, the primary purpose of this narrative review was to understand the role of the first 1000 days of life on vulnerability to drug abuse later in life. Methods: This article is a narrative review that has identified the role of the first 1000 days of life on susceptibility to substance abuse later in life. The articles were extracted from valid databases, including PubMed, Scopus, Science Direct, Web of Science, and Embase. Results: Various significant research has pointed to the mother’s distress and anxiety during pregnancy through embryonic planning, influencing the planning of the hypothalamic-pituitary-adrenal (HPA) axis and epigenetic changes. The intestinal microbiota is a part of a complex link named the microbiota-gut-brain axis that can affect drug abuse through the variety and number of intestinal microbiota. On the other hand, a mother’s drug consumption during pregnancy can function as chronic stress by affecting the enteric nervous system (ENS), which activates the concurrent axis of HPA and dopamine pathways by changing the reward circuit and the subsequent increase in drug abuse. The results indicated that various factors, such as exposure to adverse childhood experiences (ACEs), parental separation, and attachment insecurity, increase the probability of drug abuse in adulthood. Nevertheless, the quality of nurturing care during the first 1000 days of life and the mother’s warm relationship with children may hinder the increase in addiction in society. Conclusions: The first 1000 days of one's life are a crucial and delicate stage. If these days are tainted with unpleasant events, the various mechanisms can reduce a person's resilience to drug abuse in later life. How the first 1000 days of an infant’s life and the quality of this period, such as prenatal stress, substance use during pregnancy, ACEs, maternal-infant bonding, maternal separation (MS), and intestinal microbiota, can affect drug abuse in the future. As a result, focusing on the first 1000 days of life is critical to adapting prevention strategies. Health policymakers can design suitable entries during pregnancy and early childhood to reduce the probability of drug abuse.","PeriodicalId":53452,"journal":{"name":"International Journal of High Risk Behaviors and Addiction","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2022-07-11","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"89833907","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Evaluation of Matrix Metalloproteinases 2 and 9 in Oral Squamous Cell Carcinoma and Verrucous Carcinoma","authors":"M. Shahsavari, Siavash Azizi Mazreah, Azadeh Shoghi, Razieh Gheysari","doi":"10.5812/ijhrba-109491","DOIUrl":"https://doi.org/10.5812/ijhrba-109491","url":null,"abstract":"Background: Squamous cell carcinoma (SCC) is the most common malignancy of the oral cavity with a highly aggressive nature. Verrucous carcinoma (VC) is a low-grade SCC with mild clinical and pathological characteristics. Extracellular matrix degradation (ECM) by several proteolytic enzymes, especially matrix metalloproteinases (MMPs), is an important factor in tumor growth, invasion, and metastasis. Objectives: The aim of this study was to evaluate the expression level of immunohistochemistry of MMPs 2 and 9 in SCC and VC of oral cavity. Methods: The present study was conducted on the data of 20 SCC and 18 VC samples obtained from the pathology department archives. Microscopic examination was performed after immunohistochemical staining of the samples for MMP-2 and MMP-9. Data analysis was performed in SPSS 20 software. Kruskal-Wallis test was used to compare variables between groups. Results: All SCC and VC samples were positive for MMP-2 and MMP-9. The mean expression level of MMP-9 was 24.41 ± 20.68 in VC and 48.27 ± 12.11 in SCC. The mean expression level of MMP-9 in SCC was higher than VC. In addition, the expression level of MMP-9 varied in different histopathological grades of SCC. Matrix metalloproteinase expression levels were different in SCC grades and was especially higher in grade III. The mean expression level of MMP-2 in VC was 35.28 ± 30.63 and in SCC was 23.50 ± 12.68. The mean expression level of MMP-2 in VC was higher than SCC. Conclusions: Our findings showed that the expression levels of MMPs 2 and 9 in SCC and VC are higher than healthy tissue.","PeriodicalId":53452,"journal":{"name":"International Journal of High Risk Behaviors and Addiction","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2022-07-02","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"74804666","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Psychological Factors Associated With Sexual Dysfunction in Men on Methadone Maintenance Treatment","authors":"N. Bakhshani, Z. Karimi, A. Mojahed, Mohammad Javad Lavvaf Arani, Erfan Ayubi Amirabad","doi":"10.5812/ijhrba-118838","DOIUrl":"https://doi.org/10.5812/ijhrba-118838","url":null,"abstract":"Background: Methadone maintenance treatment (MMT) is an evidence-based effective treatment for drug addiction. Psychological problems are common among drug users. However, a few studies have investigated the role of psychological factors, including depression, anxiety, and childhood trauma, on sexual dysfunction in MMT patients. Objectives: This study aimed to determine the prevalence of sexual dysfunction and the role of psychological factors, including anxiety, depression, and childhood trauma, on the sexual function of patients on MMT. Patients and Methods: In this cross-sectional study, 100 MMT patients were selected by convenience sampling among patients referring to Baharan Psychiatric Hospital, Zahedan, Iran. All participants completed self-report questionnaires, including the Beck Anxiety Inventory (BAI), Beck Depression Inventory-II (BDI-II), Childhood Trauma Questionnaire (CTQ), and International Index of Erectile Function (IIEF-15). Statistical analysis was done with Pearson correlation coefficients, and stepwise linear regression models determined the predictors of sexual function. Results: Seventeen percent of participants reported various degrees of sexual dysfunction. Child sexual abuse and depression were significant predictors of sexual dysfunction. The regression analysis showed that 12% of the variance of sexual dysfunction (R2 = 0.12; F = 6.61; P < 0.002) was predicted by an experience of childhood sexual abuse and depression. Conclusions: People on MMT suffer from psychological problems as the risk factors for sexual dysfunction. Thus, mental health care staff should consider psychological factors to prevent and treat sexual dysfunction.","PeriodicalId":53452,"journal":{"name":"International Journal of High Risk Behaviors and Addiction","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2022-06-19","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"82564252","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Prevalence of Domestic Violence Among Pregnant Women in Chabahar","authors":"M. Jadgal, M. Zareipour, Ehsan Movahed, I. Zareban","doi":"10.5812/ijhrba-120410","DOIUrl":"https://doi.org/10.5812/ijhrba-120410","url":null,"abstract":"Background: Pregnancy can affect the prevalence of domestic violence during this period for various reasons, such as decreased sexual intercourse, misconceptions, and abnormal feelings about pregnancy. Objectives: This study aimed to determine the severity and frequency of domestic violence among pregnant women in Chabahar. Methods: This cross-sectional study was performed in a random cluster sample of 400 pregnant women referred to health centers in Chabahar, southeast Iran. The Dispute Resolution Measures Questionnaire collected the data. Data were entered into the computer using SPSS version 16 software and analyzed by descriptive and analytical tests. Results: Overall, 3.5% of women experienced very mild violence, 13.5% mild violence, and 83% moderate violence during pregnancy by their husbands. There was a significant relationship between total violence and pregnant women's and husbands' education (P < 0.05). Also, elementary literacy of pregnant women (OR = 4.7, P = 0.001) and husbands (OR = 6.2, P = 0.001) increased the likelihood of domestic violence among pregnant women. Conclusions: Due to the relatively high rate of moderate domestic violence, health promotion interventions, such as educating men about various dimensions of violence and its negative impact on the family, creating a culture to strengthen the status and human values of women, and holding training sessions for married men, can help reduce violence during pregnancy.","PeriodicalId":53452,"journal":{"name":"International Journal of High Risk Behaviors and Addiction","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2022-06-18","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"79581061","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"The Effect of Perphenazine Add-On Therapy to Matrix Intervention on Control of Craving and Relapse in Methamphetamine Users: A Randomized Controlled Trial","authors":"Valli Alla Nasr, M. Salehi, G. Kheirabadi","doi":"10.5812/ijhrba-115760","DOIUrl":"https://doi.org/10.5812/ijhrba-115760","url":null,"abstract":"Background: Compulsive behaviors, loss of control, and social and occupational dysfunctions are complications of methamphetamine dependence. Objectives: This study aimed to investigate the effectiveness of perphenazine on control of craving and relapse in methamphetamine users. Methods: This double-blind randomized controlled trial was performed in 2017 - 2018 in Isfahan, Iran. The samples included 40 methamphetamine-dependent subjects referred to drug rehab centers in Isfahan. While the intervention group received perphenazine for eight weeks, the control group received placebo tablets. Also, both groups were followed up for four months. Cocaine Craving Questionnaire-Brief (CCQ-Brief) was filled for each patient before and after the intervention. Results: CCQ-Brief scores were significantly lower in the intervention group compared to the control group (P < 0.0001). The changes in CCQ-Brief scores were also significant among both groups. Conclusions: Adding perphenazine to the matrix program in the treatment of methamphetamine use disorder showed significant effect on the reduction of the craving to methamphetamine.","PeriodicalId":53452,"journal":{"name":"International Journal of High Risk Behaviors and Addiction","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2022-06-15","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"91102305","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Gender Differences in the Effect of Resilience Training on Emotional Intelligence in At-Risk Students in Shiraz, Iran","authors":"H. Joulaei, Faranak Fathi, T. Rakhshani, M. Nazari, Z. Hosseinkhani, M. Fatemi, Z. Foroozanfar","doi":"10.5812/ijhrba-121942","DOIUrl":"https://doi.org/10.5812/ijhrba-121942","url":null,"abstract":"Background: Adolescence is one of the most important and challenging stages in life. psychological, cognitive and emotional changes during this period can expose adolescents to high risk behaviors. Objectives: The current study examined the effectiveness of resilience training on emotional intelligence (EI) and assessed gender differences in this regard among adolescents living in the outskirts of Shiraz, Iran. Methods: This pre-post study included 191 students and used an intervention consisting of nine resilience-training sessions. The evaluated outcomes were EI and its 15 components. The paired-samples and independent-samples t-tests were used to analyze the data. Results: Out of 191 students, 88 (46.1%) were boys. Before and after the intervention, the mean EI score for boys was 312.52 ± 37.79 and 327.31 ± 37.75, while for girls, it was 310.74 ± 30.05 and 312.20 ± 29.51, respectively. Following the intervention, the scores of boys in problem-solving (P = 0.007), happiness (P = 0.001), emotional self-awareness (P = 0.044), optimism (P = 0.029), self-regard (P = 0.046), impulse control (P = 0.013), and social responsibility (P = 0.042), as well as the total score of EI (P = 0.005), increased significantly. However, only the optimism score (P = 0.004) rose significantly in girls post-intervention. In addition, there were significant differences in the mean of problem-solving (P = 0.006), happiness (P = 0.001), impulse control (P = 0.042), and the total score (P = 0.035) between boys and girls, before and after the intervention. Conclusions: Resilience training may help moderate high-risk behaviors among adolescents living on the outskirts of Iran’s major cities, particularly boys. Based on the gender differences in EI components, it was suggested that female adolescents required significantly more attention. Nonetheless, gender differences in EI components were contentious, and it was concluded that a variety of factors, including the socio-cultural context, may be involved.","PeriodicalId":53452,"journal":{"name":"International Journal of High Risk Behaviors and Addiction","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2022-06-11","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"80271598","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Pediatric Poisonings Due to Chemical Substances and Related Factors","authors":"N. Noori, T. Boryri, Alireza Teimouri, Sahar Safapour","doi":"10.5812/ijhrba-119930","DOIUrl":"https://doi.org/10.5812/ijhrba-119930","url":null,"abstract":"Background: Pediatric poisoning is a serious issue worldwide and a common cause of children's morbidity and mortality. Objectives: This work aimed to study pediatric poisonings due to chemical substances and their related factors. Methods: A seven-year retrospective cross-sectional study was performed on the poisoning of children equal to or less than 18 years of age who presented to the emergency ward in 2014. The analyzed data included demographics and socioeconomic features, mode and route of poisoning, causative poisonous substances, clinical presentation, and patients' outcomes. The collected data were analyzed using SPSS 20, considering 0.05 as a significant error when statistical tests were used. Results: Among poisoned children, boys were more in total, as well in all age groups except > 10 years. Age (X2 = 22.494, P = 0.013), intentionally (X2 = 32.176, P < 0.001) had a significant association with chemical substances. Among the demographic and socioeconomic features, none was associated with the type of chemical substances except age. Among the symptoms, all were associated with chemical poisoning substances except seizures. Of 114 with RDS, about 30.7% were poisoned by kerosene. Of 63 with low BP, 66.7%, 31.7%, and 1.6% were due to medicines, bites, and detergents, respectively, and from six children with high BP, all were due to toxins. Of 79 with low consciousness, 69.6% were due to medicines. Seventy children had fever, of which 55.7% were due to bites. Thirty-two had seizures that 46.9% and 18.8% were due to medicines and kerosene. Ninety-seven had vomiting and nausea, of which 32% and 30.9% were due to medicines and kerosene, respectively. Finally, 159 had low SPO2, of which 47.8%, 13.8%, and 20.1% were due to medicines, toxins, and kerosene, respectively. Conclusions: It was concluded that in poisoned children, boys were more but girls in self-poisoning, especially at older ages. Girls were poisoned more by medicinal and kerosene substances, but boys by bites, toxins, and detergents. All the poisoning symptoms were observed in medicinal substances and bites. Poisoning by kerosene more occurred in the cold months, and detergents and bite poisoning were more frequent in summer. There is a need for further, longer prospective studies to lead to preventing measures.","PeriodicalId":53452,"journal":{"name":"International Journal of High Risk Behaviors and Addiction","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2022-04-08","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"89829950","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Effectiveness of Mindfulness-based Relapse Prevention Group Therapy and Treatment as Usual on Shame and Self-criticism in Individuals with Opioid Use Disorder: A Comparative Investigation","authors":"Rezvaneh Asadi Asadabad, Saeed Imani, J. Fathabadi, A. Noroozi, J. Alizadehgoradel","doi":"10.5812/ijhrba.117042","DOIUrl":"https://doi.org/10.5812/ijhrba.117042","url":null,"abstract":"Background: Shame and self-criticism are two variables that refer to negative self-assessment. Such negative self-assessments cause unpleasant emotions, which are among the known factors involved in drug abuse and relapse. Objectives: This study aimed to compare mindfulness-based relapse prevention (MBRP) group therapy and treatment as usual (TAU) in terms of their effect on shame and self-criticism in individuals with opioid use disorder (OUD). Patients and Methods: The current quasi-experimental study with a pretest-posttest and follow-up design was conducted on 36 patients who met the diagnostic and statistical manual of mental disorders (DSM-5) criteria for OUD. The participants were randomly assigned to two groups. One group received a combination of MBRP group therapy and TAU, and the other group was treated only by TAU. The participants filled out the Other as Shamer Scale and the Forms of Self-Criticizing/Attacking and Self-Reassuring Scale in the pretest, posttest, and follow-up stages. The data were statistically analyzed using a mixed-design analysis of variance. Results: Our results indicated that the mean score of shame significantly decreased in the follow-up compared to pretest and posttest. Moreover, the combination of MBRP group therapy and TAU was significantly more effective than TAU alone. The posttest and follow-up mean scores of the participants who received a combination of MBRP group therapy and TAU were significantly lower than those treated only with TAU. Conclusions: The study results showed that MBRP could be considered an effective therapeutic approach for reducing shame and self-criticism in individuals with OUD.","PeriodicalId":53452,"journal":{"name":"International Journal of High Risk Behaviors and Addiction","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2022-03-13","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"84846075","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Cultural Capital and Tobacco-related Health Literacy in Pregnant Women and the Relationship with Fetal Smoke Exposure","authors":"Afsaneh Tavassoli, Maliheh Abedi, Sara Modares Gharejedaghi","doi":"10.5812/ijhrba.118294","DOIUrl":"https://doi.org/10.5812/ijhrba.118294","url":null,"abstract":"Background: Tobacco-related health literacy is a skill for pregnant women that leads to a correct understanding of the information needed to maintain the health of the fetuses and themselves against tobacco smoke. Cultural capital is also associated with the capacity and ability to acquire skills. Objectives: This study aimed to investigate pregnant women's cultural capital and tobacco-related health literacy and the relationship with fetal smoke exposure. Methods: This cross-sectional study recruited a sample of 500 pregnant women referred to hospitals affiliated with Tehran University of Medical Sciences. The data were gathered using a researcher-made questionnaire. Results: Tobacco-related health literacy was 60.8% more common at the high level. The cultural capital of pregnant women was 81.4% higher in the medium level. Logistic regression showed that cultural capital (OR = 0.47 and B = -0.737) and tobacco-related health literacy (OR = 0.77 and B = -0.0257) reversely affected the fetal tobacco smoke exposure (P < 0.05). As women's tobacco-related health literacy and cultural capital increased, the rate of fetal smoke exposure decreased. Conclusions: According to the results, as pregnant women’s health literacy concerning tobacco smoke and their cultural capital increased, the tobacco smoke exposure of pregnant women and their fetuses decreased.","PeriodicalId":53452,"journal":{"name":"International Journal of High Risk Behaviors and Addiction","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2022-03-11","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"84635067","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}