Evaluation of Salivary Lipid Peroxidation in Paan Users

Q4 Medicine

International Journal of High Risk Behaviors and Addiction Pub Date : 2022-07-19 DOI:10.5812/ijhrba-123907

L. Farhad-Mollashahi, Z. Dalirsani, A. Nakhaee, Vahid Sahraie

{"title":"Evaluation of Salivary Lipid Peroxidation in Paan Users","authors":"L. Farhad-Mollashahi, Z. Dalirsani, A. Nakhaee, Vahid Sahraie","doi":"10.5812/ijhrba-123907","DOIUrl":null,"url":null,"abstract":"Background: One known risk factor for oral cancer is chewing smokeless tobacco, which is common in southeastern Iran. Smokeless tobacco-related oral complications can be evaluated by assessing parameters of oxidative stress. Objectives: This study evaluated salivary malondialdehyde (MDA) levels in paan users and compared them with nonusers. Patients and Methods: In this study, saliva was collected from 50 paan users and 50 nonusers referred to the Zahedan Dental School in Zahedan, Iran. Salivary MDA was assessed based on standard biochemical methods, and the data were analyzed using a t-test and analysis of variance. Results: In the paan users and the controls, the mean MDA was 2.19 ± 1.05 and 1.24 ± 0.62 (nmol/mL), respectively, and both groups showed significant differences (P < 0.001). The daily consumption and duration were significantly correlated with the MDA concentration, respectively (r = 0.722, P < 0.001), (r = 0.764, P < 0.001). Conclusions: In paan users, salivary MDA concentrations were higher. The concentration of salivary MDA increased with the consumption of paan in more significant quantities and for a more extended time.","PeriodicalId":53452,"journal":{"name":"International Journal of High Risk Behaviors and Addiction","volume":"22 1","pages":""},"PeriodicalIF":0.0000,"publicationDate":"2022-07-19","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"0","resultStr":null,"platform":"Semanticscholar","paperid":null,"PeriodicalName":"International Journal of High Risk Behaviors and Addiction","FirstCategoryId":"1085","ListUrlMain":"https://doi.org/10.5812/ijhrba-123907","RegionNum":0,"RegionCategory":null,"ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"Q4","JCRName":"Medicine","Score":null,"Total":0}

引用次数: 0

Abstract

Background: One known risk factor for oral cancer is chewing smokeless tobacco, which is common in southeastern Iran. Smokeless tobacco-related oral complications can be evaluated by assessing parameters of oxidative stress. Objectives: This study evaluated salivary malondialdehyde (MDA) levels in paan users and compared them with nonusers. Patients and Methods: In this study, saliva was collected from 50 paan users and 50 nonusers referred to the Zahedan Dental School in Zahedan, Iran. Salivary MDA was assessed based on standard biochemical methods, and the data were analyzed using a t-test and analysis of variance. Results: In the paan users and the controls, the mean MDA was 2.19 ± 1.05 and 1.24 ± 0.62 (nmol/mL), respectively, and both groups showed significant differences (P < 0.001). The daily consumption and duration were significantly correlated with the MDA concentration, respectively (r = 0.722, P < 0.001), (r = 0.764, P < 0.001). Conclusions: In paan users, salivary MDA concentrations were higher. The concentration of salivary MDA increased with the consumption of paan in more significant quantities and for a more extended time.

查看原文本刊更多论文

Paan使用者唾液脂质过氧化的评价

背景:口腔癌的一个已知危险因素是咀嚼无烟烟草，这在伊朗东南部很常见。无烟烟草相关的口腔并发症可通过评估氧化应激参数来评估。目的:本研究评估paan使用者唾液丙二醛(MDA)水平，并将其与非使用者进行比较。患者和方法:在这项研究中，收集了来自伊朗扎黑丹扎黑丹牙科学校的50名paan使用者和50名非使用者的唾液。唾液MDA测定采用标准生化方法，数据采用t检验和方差分析。结果:paan使用者和对照组的MDA均值分别为2.19±1.05和1.24±0.62 (nmol/mL)，两组差异有统计学意义(P < 0.001)。日摄取量和持续时间与MDA浓度分别呈显著相关(r = 0.722, P < 0.001)和显著相关(r = 0.764, P < 0.001)。结论:paan使用者唾液丙二醛浓度较高。唾液丙二醛的浓度随着paan的摄入而增加，且增加的量更显著，持续的时间更长。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

求助全文

约1分钟内获得全文求助全文

来源期刊

International Journal of High Risk Behaviors and Addiction Psychology-Clinical Psychology

CiteScore

0.70

自引率

0.00%

发文量

期刊介绍： International Journal of High Risk Behaviors and Addiction is a clinical journal which is informative to all fields related to the high risk behaviors, addiction, including smoking, alcohol consumption and substance abuse, unsafe sexual behavior, obesity and unhealthy eating habits, physical inactivity, and violence, suicidal behavior, and self-injurious behaviors. International Journal of High Risk Behaviors and Addiction is an authentic clinical journal which its content is devoted to the particular compilation of the latest worldwide and interdisciplinary approach and findings including original manuscripts, meta-analyses and reviews, health economic papers, debates, and consensus statements of the clinical relevance of Risky behaviors and addiction. In addition, consensus evidential reports not only highlight the new observations, original research and results accompanied by innovative treatments and all the other relevant topics but also include highlighting disease mechanisms or important clinical observations and letters on articles published in this journal.