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Beyond weight: Exploring the nexus between obesity and osteoarthritis 超越体重：探索肥胖和骨关节炎之间的关系
IF 0.9
Medicina de Familia-SEMERGEN Pub Date : 2025-05-30 DOI: 10.1016/j.semerg.2025.102526
M.C. Ningtyas , B.A. Ansharullah , H. Sutanto , J.H. Prajitno
{"title":"Beyond weight: Exploring the nexus between obesity and osteoarthritis","authors":"M.C. Ningtyas ,&nbsp;B.A. Ansharullah ,&nbsp;H. Sutanto ,&nbsp;J.H. Prajitno","doi":"10.1016/j.semerg.2025.102526","DOIUrl":"10.1016/j.semerg.2025.102526","url":null,"abstract":"<div><div>Obesity is a well-established risk factor for osteoarthritis (OA), traditionally attributed to increased mechanical stress on weight-bearing joints. However, recent research suggests a more complex interplay, involving metabolic, biomechanical, and inflammatory pathways. This review delves into these multifaceted connections between obesity and osteoarthritis, extending beyond the conventional understanding of weight-bearing stress. It explores the role of adipokines such as leptin, visfatin, adiponectin, and resistin in OA pathogenesis and progression, highlighting their potential as targets for novel therapeutics. The review also examines how obesity alters the biomechanics of lower extremities, contributing to changes in joint load and movement patterns. Systemic effects, including inflammation and metabolic factors, are discussed to elucidate their roles in exacerbating OA beyond joint loading. Furthermore, the impact of bariatric surgery and weight loss strategies on OA symptoms and progression is evaluated. This comprehensive review aims to provide new insights into obesity-induced OA, paving the way for more targeted and effective treatment strategies.</div></div>","PeriodicalId":53212,"journal":{"name":"Medicina de Familia-SEMERGEN","volume":"51 6","pages":"Article 102526"},"PeriodicalIF":0.9,"publicationDate":"2025-05-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144170688","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Riesgo de enfermedad del hígado graso asociada a la disfunción metabólica en 44.939 trabajadores sanitarios españoles: variables asociadas 44 939名西班牙卫生工作者患与代谢功能障碍有关的脂肪肝风险：相关变量
IF 0.9
Medicina de Familia-SEMERGEN Pub Date : 2025-05-30 DOI: 10.1016/j.semerg.2025.102514
P.J. Tárraga Marcos , Á.A. López-González , E. Martínez-Almoyna Rifá , H. Paublini Oliveira , C. Martorell Sánchez , P.J. Tárraga López , J.I. Ramírez-Manent
{"title":"Riesgo de enfermedad del hígado graso asociada a la disfunción metabólica en 44.939 trabajadores sanitarios españoles: variables asociadas","authors":"P.J. Tárraga Marcos ,&nbsp;Á.A. López-González ,&nbsp;E. Martínez-Almoyna Rifá ,&nbsp;H. Paublini Oliveira ,&nbsp;C. Martorell Sánchez ,&nbsp;P.J. Tárraga López ,&nbsp;J.I. Ramírez-Manent","doi":"10.1016/j.semerg.2025.102514","DOIUrl":"10.1016/j.semerg.2025.102514","url":null,"abstract":"<div><h3>Objective</h3><div>To assess the association between sociodemographic variables and lifestyle habits with the risk of metabolic dysfunction-associated fatty liver disease (MASLD) in Spanish healthcare workers.</div></div><div><h3>Methods</h3><div>A cross-sectional study including 44,939 healthcare workers. Sociodemographic variables (age, sex, occupation) and lifestyle habits (smoking, physical activity, adherence to the Mediterranean diet) were analyzed in relation to MASLD risk scores (FLI, HSI, LAP, ZJU, and FLD). Multinomial logistic regression models were used to identify significant associations.</div></div><div><h3>Results</h3><div>Higher risk score values were more prevalent in men and increased with age. Nursing assistants and orderlies had a higher risk compared to physicians. Physical inactivity (OR<!--> <!-->=<!--> <!-->2.65; 95% CI: 2.47-2.84) and low adherence to the Mediterranean diet (OR<!--> <!-->=<!--> <!-->1.89; 95% CI: 1.69-2.10) were associated with an increased risk of MASLD. Smoking was significantly related to higher risk scores (OR<!--> <!-->=<!--> <!-->1.17; 95% CI: 1.13-1.21).</div></div><div><h3>Conclusions</h3><div>Age, sex, occupation, smoking, physical activity, and adherence to the Mediterranean diet influence MASLD risk. Preventive strategies should focus on promoting physical activity, improving dietary habits, and reducing smoking among healthcare workers.</div></div>","PeriodicalId":53212,"journal":{"name":"Medicina de Familia-SEMERGEN","volume":"51 7","pages":"Article 102514"},"PeriodicalIF":0.9,"publicationDate":"2025-05-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144177551","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Identificación y abordaje de las necesidades paliativas en la consulta de atención primaria. Una propuesta práctica 确定和解决初级保健咨询中的姑息治疗需求。实用的建议
IF 0.9
Medicina de Familia-SEMERGEN Pub Date : 2025-05-30 DOI: 10.1016/j.semerg.2025.102528
F.J. Resa López
{"title":"Identificación y abordaje de las necesidades paliativas en la consulta de atención primaria. Una propuesta práctica","authors":"F.J. Resa López","doi":"10.1016/j.semerg.2025.102528","DOIUrl":"10.1016/j.semerg.2025.102528","url":null,"abstract":"<div><div>The heterogeneous and unique characteristics of advanced disease frequently compromise the emotional adjustment of patients and families, generating a high demand for care.</div><div>These conditions often exceed approaches based on protocols and clinical guidelines, making an adequate, individualized and precise situational diagnosis essential, which facilitates an efficient shared decision-making and a quality patient-centered care.</div><div>Palliative care, therefore, should be based on the degree of care complexity, determined by the needs of the patient-family unit and the problem-solving capacity of healthcare resources, with the community being an environment of specific complexity.</div><div>Identifying these needs early allows for a more humane, personalized and effective care, improving the experience of the disease process.</div><div>Due to their position in the healthcare system as well as their comprehensive and continuous knowledge of their patients, family doctors can and should play a crucial role in this process.</div></div>","PeriodicalId":53212,"journal":{"name":"Medicina de Familia-SEMERGEN","volume":"51 7","pages":"Article 102528"},"PeriodicalIF":0.9,"publicationDate":"2025-05-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144169611","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Del metabolismo a la piel: GLP-1 y su potencial en hidradenitis supurativa 从新陈代谢到皮肤：GLP-1及其在化脓性水腺炎中的潜力
IF 0.9
Medicina de Familia-SEMERGEN Pub Date : 2025-05-27 DOI: 10.1016/j.semerg.2025.102524
D. García Elices , M.L. García Martínez , M. Romero Sanabria , L. Fernández Matas
{"title":"Del metabolismo a la piel: GLP-1 y su potencial en hidradenitis supurativa","authors":"D. García Elices ,&nbsp;M.L. García Martínez ,&nbsp;M. Romero Sanabria ,&nbsp;L. Fernández Matas","doi":"10.1016/j.semerg.2025.102524","DOIUrl":"10.1016/j.semerg.2025.102524","url":null,"abstract":"","PeriodicalId":53212,"journal":{"name":"Medicina de Familia-SEMERGEN","volume":"51 7","pages":"Article 102524"},"PeriodicalIF":0.9,"publicationDate":"2025-05-27","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144139337","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Factores que favorecen la cicatrización en la medicina actual 现代医学中促进愈合的因素
IF 0.9
Medicina de Familia-SEMERGEN Pub Date : 2025-05-27 DOI: 10.1016/j.semerg.2025.102513
D. García Elices , M.L. García Martínez , P. Arbués Espinosa
{"title":"Factores que favorecen la cicatrización en la medicina actual","authors":"D. García Elices ,&nbsp;M.L. García Martínez ,&nbsp;P. Arbués Espinosa","doi":"10.1016/j.semerg.2025.102513","DOIUrl":"10.1016/j.semerg.2025.102513","url":null,"abstract":"<div><div>Medicine offers a wide range of possibilities that can help the physician to improve the wound healing process and obtain satisfactory aesthetic results for the patient.</div><div>Healing is a complex process that is influenced by both exogenous and endogenous factors, ranging from the patient's nutritional status to the length of time the wound has been healing. These factors can act both to the benefit and detriment of proper healing.</div><div>Hyaluronic acid, carboxytherapy, light-based therapies such as laser and proper nutrition are some of the most widely described elements that allow us to influence these factors in favour of better healing.</div><div>.</div></div>","PeriodicalId":53212,"journal":{"name":"Medicina de Familia-SEMERGEN","volume":"51 7","pages":"Article 102513"},"PeriodicalIF":0.9,"publicationDate":"2025-05-27","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144139338","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
«La medicina del asterisco»: de la alarma infundada al sobrediagnóstico evitable “星药”：从毫无根据的恐慌到可以避免的过度诊断
IF 0.9
Medicina de Familia-SEMERGEN Pub Date : 2025-05-27 DOI: 10.1016/j.semerg.2025.102523
J.C. Romero Vigara , E. Trillo Calvo , J. Romero Berto
{"title":"«La medicina del asterisco»: de la alarma infundada al sobrediagnóstico evitable","authors":"J.C. Romero Vigara ,&nbsp;E. Trillo Calvo ,&nbsp;J. Romero Berto","doi":"10.1016/j.semerg.2025.102523","DOIUrl":"10.1016/j.semerg.2025.102523","url":null,"abstract":"","PeriodicalId":53212,"journal":{"name":"Medicina de Familia-SEMERGEN","volume":"51 7","pages":"Article 102523"},"PeriodicalIF":0.9,"publicationDate":"2025-05-27","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144139336","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Ideación suicida por pregabalina. Caso clínico en atención primaria 自杀的想法，普瑞巴林。初级保健中的临床病例
IF 0.9
Medicina de Familia-SEMERGEN Pub Date : 2025-05-22 DOI: 10.1016/j.semerg.2025.102505
A.M. López Carabaño , M. Escudero Araus , J.J. Docavo Barrenechea-Moxo , J. Bengoechea Aldaz
{"title":"Ideación suicida por pregabalina. Caso clínico en atención primaria","authors":"A.M. López Carabaño ,&nbsp;M. Escudero Araus ,&nbsp;J.J. Docavo Barrenechea-Moxo ,&nbsp;J. Bengoechea Aldaz","doi":"10.1016/j.semerg.2025.102505","DOIUrl":"10.1016/j.semerg.2025.102505","url":null,"abstract":"","PeriodicalId":53212,"journal":{"name":"Medicina de Familia-SEMERGEN","volume":"51 5","pages":"Article 102505"},"PeriodicalIF":0.9,"publicationDate":"2025-05-22","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144115145","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Dermatología en medicina paliativa: más allá de las úlceras 缓和医学中的皮肤学：超越溃疡
IF 0.9
Medicina de Familia-SEMERGEN Pub Date : 2025-05-22 DOI: 10.1016/j.semerg.2025.102511
V. de la Cuesta Esteban , A. Medina Cobos , F.J. Resa López
{"title":"Dermatología en medicina paliativa: más allá de las úlceras","authors":"V. de la Cuesta Esteban ,&nbsp;A. Medina Cobos ,&nbsp;F.J. Resa López","doi":"10.1016/j.semerg.2025.102511","DOIUrl":"10.1016/j.semerg.2025.102511","url":null,"abstract":"","PeriodicalId":53212,"journal":{"name":"Medicina de Familia-SEMERGEN","volume":"51 8","pages":"Article 102511"},"PeriodicalIF":0.9,"publicationDate":"2025-05-22","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144115535","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Linfoma post-COVID en la infancia: ¿casualidad o causalidad? 2019冠状病毒病后的儿童淋巴瘤：是偶然还是因果关系？
IF 0.9
Medicina de Familia-SEMERGEN Pub Date : 2025-05-22 DOI: 10.1016/j.semerg.2025.102522
C. Carrasco Noguero, A. Wandosell Álvarez, B. Sancho Sanroma, R. de la Fuente Cañíbano, J. Crespo del Hierro
{"title":"Linfoma post-COVID en la infancia: ¿casualidad o causalidad?","authors":"C. Carrasco Noguero,&nbsp;A. Wandosell Álvarez,&nbsp;B. Sancho Sanroma,&nbsp;R. de la Fuente Cañíbano,&nbsp;J. Crespo del Hierro","doi":"10.1016/j.semerg.2025.102522","DOIUrl":"10.1016/j.semerg.2025.102522","url":null,"abstract":"","PeriodicalId":53212,"journal":{"name":"Medicina de Familia-SEMERGEN","volume":"51 8","pages":"Article 102522"},"PeriodicalIF":0.9,"publicationDate":"2025-05-22","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144105128","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Disnea en el anciano, más allá de lo típico 在老人的Disnia，超越了典型的
IF 0.9
Medicina de Familia-SEMERGEN Pub Date : 2025-05-22 DOI: 10.1016/j.semerg.2025.102520
L. Hernández-Camacho , M.E. Charte Alegre , M. Lalueza Cosculluela , A. Fournier Bedoya , A.B. Solano Checa
{"title":"Disnea en el anciano, más allá de lo típico","authors":"L. Hernández-Camacho ,&nbsp;M.E. Charte Alegre ,&nbsp;M. Lalueza Cosculluela ,&nbsp;A. Fournier Bedoya ,&nbsp;A.B. Solano Checa","doi":"10.1016/j.semerg.2025.102520","DOIUrl":"10.1016/j.semerg.2025.102520","url":null,"abstract":"","PeriodicalId":53212,"journal":{"name":"Medicina de Familia-SEMERGEN","volume":"51 8","pages":"Article 102520"},"PeriodicalIF":0.9,"publicationDate":"2025-05-22","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144115533","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
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