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COVID-19 infection in pregnant women with preeclampsia and HELLP syndrome, with possible vertical transmission to the fetus: a case report 患有子痫前期和HELLP综合征的孕妇感染COVID-19,可能垂直传播给胎儿:1例报告
Medisains Pub Date : 2022-09-15 DOI: 10.30595/medisains.v20i2.14036
Sulistiari Retnowati, Alfaina Wahyuni, Nabila A Pramono
{"title":"COVID-19 infection in pregnant women with preeclampsia and HELLP syndrome, with possible vertical transmission to the fetus: a case report","authors":"Sulistiari Retnowati, Alfaina Wahyuni, Nabila A Pramono","doi":"10.30595/medisains.v20i2.14036","DOIUrl":"https://doi.org/10.30595/medisains.v20i2.14036","url":null,"abstract":"Background: During pregnancy, a woman's immune cells undergo cellular and functional alterations, rendering them more vulnerable to illness. Preeclampsia and HELLP syndromes are pregnancy problems and one of Indonesia's leading causes of maternal mortality; COVID-19 infection would exacerbate the situation. The evidence for COVID-19 vertical transmission is not well established, and the report on the incidence of vertical transmission, especially in Indonesia, is still limited.Case presentation: We discuss the case of a 26-year-old, 36 weeks of gestation, with preeclampsia and HELLP syndrome, who was infected with COVID-19 and got severe pneumonia and ARDS. The infant was born by cesarean section, and there was no contact between the infant and mother following delivery. Based on the results of the PCR examination, the baby was also confirmed to have COVID-19 without any symptoms.Conclusion: Vertical transmission during pregnancy is possible in women with a severe type of COVID-19 with preeclampsia and HELLP syndrome.","PeriodicalId":52913,"journal":{"name":"Medisains","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2022-09-15","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"45872586","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Depression and prevention during the COVID-19 pandemic COVID-19大流行期间的抑郁与预防
Medisains Pub Date : 2022-09-15 DOI: 10.30595/medisains.v20i2.15066
Juli Widiyanto, Silvia Elki Putri
{"title":"Depression and prevention during the COVID-19 pandemic","authors":"Juli Widiyanto, Silvia Elki Putri","doi":"10.30595/medisains.v20i2.15066","DOIUrl":"https://doi.org/10.30595/medisains.v20i2.15066","url":null,"abstract":"The impact of the COVID-19 pandemic affects all aspects, namely aspects of health, economy, education, and social life. Depression is a problem that everyone is at risk of experiencing during the COVID-19 pandemic. The condition of depression dramatically affects quality and productivity, primarily if it occurs at a productive age. Depression requires primary, secondary, and tertiary prevention at individual, family, group, and community levels.","PeriodicalId":52913,"journal":{"name":"Medisains","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2022-09-15","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"44079001","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Drink combination made from Fenugreek seeds and Phoenix dac-tylifera to increase prolactin hormone levels in postpartum mothers and its impact on baby weight 由胡芦巴籽和凤凰花混合制成的饮料,可以提高产后母亲的催乳激素水平,并对婴儿体重产生影响
Medisains Pub Date : 2022-09-15 DOI: 10.30595/medisains.v20i2.14240
S. Halimah, Krisdiana Wijayanti, Taadi Taadi
{"title":"Drink combination made from Fenugreek seeds and Phoenix dac-tylifera to increase prolactin hormone levels in postpartum mothers and its impact on baby weight","authors":"S. Halimah, Krisdiana Wijayanti, Taadi Taadi","doi":"10.30595/medisains.v20i2.14240","DOIUrl":"https://doi.org/10.30595/medisains.v20i2.14240","url":null,"abstract":"Background: Breast milk is the best leading food for the growth and development of the baby; however, the production of breast milk produced by breastfeeding mothers is still lacking and impacts the baby's weight. One of the efforts is consuming a combination drink of Fenugreek seeds and Phoenix dactylifera containing galactagogue, which has never been done in this study before, to see an increase in breast milk production from indicators of prolactin hormone levels and its impact on baby weight.Purpose: Knowing the effect of giving drinks a combination of Fenugreek seeds and Phoenix dactylifera on the hormone prolactin and its impact on baby weight.Methods: This is an experimental study with a combination design, pretest-posttest, and posttest-only design. Respondents totaled 32 breastfeeding mothers, 16 were given drinks combination of Fenugreek seeds and Phoenix dactylifera, and 16 were given Phoenix dactylifera drinks. The intervention was given for 14 days, and the Mann-Whitney test analyzed prolactin hormone and baby weight using the Independent T-test.Results: Mean levels of the hormone prolactin in the intervention group were higher (279.52 ng/ml) than in the control group (263.31 ng/ml) with p>0.05. The average increase in body weight of infants of the intervention group (606.25 g) was higher than the control group (381.25 g) with a p<0.05.Conclusion: A drink combination made from Fenugreek seeds and Phoenix dactylifera can increase hormone prolactin. However, it is not statistically meaningful, and mothers who consume drinks have babies weighing higher than mothers who only give Phoenix dactylifera drinks.","PeriodicalId":52913,"journal":{"name":"Medisains","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2022-09-15","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"46755844","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Progressive muscle relaxation application (PURE App) for dysmenorrhea 渐进式肌肉放松应用(PURE App)治疗痛经
Medisains Pub Date : 2022-09-15 DOI: 10.30595/medisains.v20i2.14351
Tharra Widadari Aldinda, S. Sumarni, D. K. Mulyantoro, M. Azam, S. Sudiyono
{"title":"Progressive muscle relaxation application (PURE App) for dysmenorrhea","authors":"Tharra Widadari Aldinda, S. Sumarni, D. K. Mulyantoro, M. Azam, S. Sudiyono","doi":"10.30595/medisains.v20i2.14351","DOIUrl":"https://doi.org/10.30595/medisains.v20i2.14351","url":null,"abstract":"Background: The prevalence of primary dysmenorrhea in Indonesia is 54.89%. Progressive Muscle Relaxation (PMR) exercises have proven to decrease the symptoms of dysmenorrhea. Nowadays, the android application can be widely accessed anywhere and anytime, thus saving time and costs. There has never been a study that applies PMR, especially android-based dysmenorrhoea.Objective: The current study aimed to develop the PURE App, a PMR exercise android-based application, and to test the effectiveness of reducing the menstrual pain score of adolescents with primary dysmenorrhea.Method: This study conducted Research and Development (R&D), which consists of 4 stages, namely information collection, application design, expert validation and revision, and trial.Result: The PURE App has five features, ranging from pain screening to exercise. The trial results showed that the PURE App application effectively reduced menstrual pain in adolescents with dysmenorrhea. The treatment decreased pain score from 4.48±0.71 to 1.98±1.49 in the treatment group (p<0.001). The treatment group's post-measurement pain score was also significantly different compared to the control group, 1.98±1.49 and 4.90±1.10, respectively.Conclusion: The PURE App benefits teenagers, especially those with primary dysmenorrhea. This application will make it easier for teenagers to overcome pain because the exercises on the application can be accessed anytime and anywhere.","PeriodicalId":52913,"journal":{"name":"Medisains","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2022-09-15","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"48028781","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Models of antenatal classes for pregnant mothers 孕妇产前培训班模式
Medisains Pub Date : 2022-04-30 DOI: 10.30595/medisains.v20i1.12820
A. Sriatmi, S. Suwitri, Z. Shaluhiyah, S. Nugraheni
{"title":"Models of antenatal classes for pregnant mothers","authors":"A. Sriatmi, S. Suwitri, Z. Shaluhiyah, S. Nugraheni","doi":"10.30595/medisains.v20i1.12820","DOIUrl":"https://doi.org/10.30595/medisains.v20i1.12820","url":null,"abstract":"Introduction: Although it has proven to be helpful, the attendance of pregnant mothers in Antenatal Classes (AC) was still low, so an ineffective breakthrough application of AC was needed according to the mother's wishes and interests.Objective: The study aimed to compare various models of practical AC for pregnant mothers to improve behavior prevention of high-risk pregnancies.Method: This study is quasi-experimental with a nonequivalent control group and pre-posttest design. The population of all pregnant mothers in Semarang City, with 181 samples, was divided into three groups (Extended, Virtual and Conventional). Measurements were carried out four times to see the mean score increasing, and the results of the last measurement were analyzed using the One Way ANOVA test to compare the effectiveness of these three groups.Results: There was an increase in the mean value of all dimensions of the behavior of high-risk prevention based on its measurement stages. The extended model has the highest improvement, followed by the Virtual model. Statistically, there was a better chance in all behavioral dimensions after the intervention. There were differences in all dimensions of maternal behavior between the extended and the conventional model. In contrast, only knowledge and practice differed in the virtual model but not in attitudes, beliefs, and intentions.Conclusion: Extended and virtual models of AC effectively improved high-risk prevention behaviors better than conventional models. Although the increase was not as high as the extended model, the virtual model has an excellent opportunity to be developed as a strategy to overcome time constraints for mothers and health providers.","PeriodicalId":52913,"journal":{"name":"Medisains","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2022-04-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"49006673","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Calcium supplementation from chicken eggshells to increase nitric oxide levels and control blood pressure in gestational hypertension 从鸡蛋壳中补充钙以增加一氧化氮水平和控制妊娠期高血压的血压
Medisains Pub Date : 2022-04-30 DOI: 10.30595/medisains.v20i1.13378
Aulia Agyanti Rahmah, S. Hadisaputro, EnyRetna Ambarwati
{"title":"Calcium supplementation from chicken eggshells to increase nitric oxide levels and control blood pressure in gestational hypertension","authors":"Aulia Agyanti Rahmah, S. Hadisaputro, EnyRetna Ambarwati","doi":"10.30595/medisains.v20i1.13378","DOIUrl":"https://doi.org/10.30595/medisains.v20i1.13378","url":null,"abstract":"Background: Hypertension is one of the highest causes of death in pregnant women. Calcium deficiency can lead to hypertension. Chicken eggshell can be used as a natural calcium supplementation therapy in hypertension.Purpose: Analyze the effect of chicken eggshell on blood pressure through the increased nitric oxide level in gestational hypertension.Methods: This is Quasy experiment research with pretest and posttest with control group design. Respondents were ≥20 weeks pregnant women with gestational hypertension. Determination of respondents by purposive sampling obtained experimental group (n=12) and control group (n=12). 1.1 g/day of eggshell flour was given for 14 days.Result: Mean of systolic and diastolic blood pressure in experimental group decreased 14.25 mmHg or 9.5% (p=0.000) and 12.84 mmHg or 13.04% (p=0.000) after received chicken eggshell flour for 14 days compared to control group mean of systolic and diastolic blood pressure increased 1.92 mmHg or 1.35% (p=0.000) and 0.33 mmHg or 0,34% (p=0.121). Nitrit oxide level of experimental group increased 8.250 μmol/L or 20.93% (p=0.020) and control group decreased 3.083 μmol/L or 7.20% (p=0.488).Conclusion: Chicken eggshell flour affects increasing nitric oxide levels and controls systolic and diastolic blood pressure in gestational hypertension.","PeriodicalId":52913,"journal":{"name":"Medisains","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2022-04-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"42831002","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
In vivo study of cardioprotective effect of bay leaf (Syzygium polyanthum) extract 月桂叶提取物心脏保护作用的体内研究
Medisains Pub Date : 2022-04-30 DOI: 10.30595/medisains.v20i1.12502
Refi Ikhtiari, Laura Kartika Sari, A. N. Nasution, C. Ginting, Erwin Handoko, I. Lister
{"title":"In vivo study of cardioprotective effect of bay leaf (Syzygium polyanthum) extract","authors":"Refi Ikhtiari, Laura Kartika Sari, A. N. Nasution, C. Ginting, Erwin Handoko, I. Lister","doi":"10.30595/medisains.v20i1.12502","DOIUrl":"https://doi.org/10.30595/medisains.v20i1.12502","url":null,"abstract":"Background: The excessive use of chemotherapy drugs such as doxorubicin might induce cardiovascular diseases. Heart-specific biomarker enzymes such as LDH and BNP indicated the early signs of cardiotoxicity. However, there is no report on the effect of bay leaf on LDH and BNP nor its bioactive compounds and histopathology analysis.Objective: This study aims to determine the cardioprotective effect of Ethanol Extract of Bay Leaf (EEBL) based on phytochemical analysis, LDH and BNP levels, and cardiac histology of rats administered with doxorubicin.Methods: About 24 Wistar rats were divided into six groups treated with 100 mg/kg BW, 300 mg/kg BW, and 500 mg/kg BW of EEBL with CMC-Na 0.5 %, vitamin E, and doxorubicin. Preconditioning was 14 days, followed by 21 days of intraperitoneal administration. LDH and BNP parameters were measured on days 1st, 7th, 14th, and 20th. Histology analysis was conducted on day 21st.Results: Dark green EEBL showed sufficient physical quality and properties for practical application in pharmacy. EEBL has significantly affected LDH, BNP, and cardio recovery dose-dependent. The most effective doses were observed at 500 mg/kg BW, and its performance is not statistically different from those of the commercial vitamin E. The histopathological images revealed significant improvements in interstitial edema, wavy fibers, hemorrhage, intracellular vacuole, and inflammatory cell infiltration. Here we report six bioactive compounds obtained from EEBL have cardioprotective effects; Neophytadiene, squalane, phytol, methyl palmitate, stigmasterol, and  9,12-Octadecanoic acid methyl ester.Conclusion: This study has shown the promising potential of bay leaf extract as a cardioprotector with sufficient quality pharmacological standards.","PeriodicalId":52913,"journal":{"name":"Medisains","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2022-04-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"46876692","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Development of an electronic measuring device for body weight and nutritional status for children under two years old 研制两岁以下儿童体重和营养状况电子测量装置
Medisains Pub Date : 2022-04-30 DOI: 10.30595/medisains.v20i1.13143
Naimah Nasution, M. Widyawati, D. Ramlan
{"title":"Development of an electronic measuring device for body weight and nutritional status for children under two years old","authors":"Naimah Nasution, M. Widyawati, D. Ramlan","doi":"10.30595/medisains.v20i1.13143","DOIUrl":"https://doi.org/10.30595/medisains.v20i1.13143","url":null,"abstract":"Background: Measurement of body weight and nutritional status in children under two years are still used manuals. Besides that, there is no tool to measure nutritional status, so it is necessary to develop a tool to make it easier.Purpose: The study aims to develop and test a measuring device for weight and nutritional status in children under two years.Methods: This study is Research and Development (R&D). It consisted of 5 stages, stage I (literature study), stage II (product development), stage III (expert validity and phase I trials), stage IV (product revision and final product), and stage V (phase II trials).Result: The electronic measuring device for weight and nutritional status has been created. The result is that the tool effectively determines the weight and nutritional status. The average value of tool testing is below 5%, which means the calibration value of the tool's sensitivity is valid in determining body weight. In addition, it can also determine nutritional status with a p=0,65, which means that there is no difference between measuring nutritional status using the tool and manually.Conclusion: The electronic measuring device effectively determines the weight and nutritional status.","PeriodicalId":52913,"journal":{"name":"Medisains","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2022-04-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"45764429","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
From global to local action: rise from the pandemic, an efforts to increase routine immunization coverage 从全球行动到地方行动:从大流行中崛起,努力提高常规免疫覆盖率
Medisains Pub Date : 2022-04-30 DOI: 10.30595/medisains.v20i1.13586
D. Purwito
{"title":"From global to local action: rise from the pandemic, an efforts to increase routine immunization coverage","authors":"D. Purwito","doi":"10.30595/medisains.v20i1.13586","DOIUrl":"https://doi.org/10.30595/medisains.v20i1.13586","url":null,"abstract":"Since the first vaccine was developed (1796; smallpox vaccine), the world has seen its impact on health and well-being. Vaccines are one of the most influential scientific innovations of all time, helping to protect generations of people from infectious diseases throughout their lives. Parents need not worry too much about their children suffering from a deadly disease that has plagued previous generations because of vaccines. However, a top-down approach is needed so that vaccination becomes necessary for every people worldwide.","PeriodicalId":52913,"journal":{"name":"Medisains","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2022-04-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"47577413","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 1
Frailty among hemodialysis patients 血液透析患者的虚弱
Medisains Pub Date : 2022-04-30 DOI: 10.30595/medisains.v20i1.12374
G. S. Adi, Eri Purba Utomo
{"title":"Frailty among hemodialysis patients","authors":"G. S. Adi, Eri Purba Utomo","doi":"10.30595/medisains.v20i1.12374","DOIUrl":"https://doi.org/10.30595/medisains.v20i1.12374","url":null,"abstract":"Introduction: Hemodialysis patients have physical vulnerability due to the progressive decline of the body's systems. The physical changes in the patients can lead to haemostatics failure, known as frailty syndrome. The frail condition can cause maladaptive psychological responses due to changes that can cause anxiety in patients.Objective: This study aims to determine the prevalence of frailty in hemodialysis patients and to find out the different factor that correlates in frailty patients undergoing hemodialysis therapy.Method: This is a cross-sectional study involving 55 respondents who underwent hemodialysis therapy at the Jember Klinik Hospital. The instruments used in this study were the Edmonton Frail Scale (EFS) and the Hamilton Anxiety Rating Scale. Results: Moderate frailty was found in 23 patients (41.8%), followed by mild frailty in 18 patients (32.7%) and severe frailty in 14 patients (25.5%). In terms of anxiety, 18 patients (32.7%) had severe anxiety, 20 had moderate anxiety (36.4%), 12 (21.8%) had mild anxiety, and the other 7 (12.7%) were not anxious. The statistical analysis shows a significant difference in the average level of anxiety and the frailty status (p<0.001) among the patients. Conclusion: Frailty was highly prevalent in hemodialysis patients and had relations with anxiety and different sociodemographic characteristics of patients. The assessment of frailty should be considered when clinicians intervene and prevent worsening in patients.","PeriodicalId":52913,"journal":{"name":"Medisains","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2022-04-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"42695083","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
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