Current Pollution Reports最新文献

{"title":"An Overview of the Potential for Municipal Wastewater Treatment Plants to Be Integrated into Urban Biorefineries for the Production of Sustainable Bio-Based Fuels and Other Chemicals","authors":"Bimi Shrestha,&nbsp;Blake Foret,&nbsp;Wayne Sharp,&nbsp;Daniel Gang,&nbsp;Rafael Hernandez,&nbsp;Emmanuel Revellame,&nbsp;Dhan Lord B. Fortela,&nbsp;William E. Holmes,&nbsp;Mark E. Zappi","doi":"10.1007/s40726-024-00318-6","DOIUrl":"10.1007/s40726-024-00318-6","url":null,"abstract":"<div><h3>Purpose of Review</h3><p>An increase in the generation of waste within cities is unavoidable due to the increasing global population growth, particularly in urban areas. Municipal wastewater treatment plants (WWTPs) in these urban areas are being pushed to their design limits resulting in issues with WWTP residual management. This paper reviews potential applications of transitioning a municipal WWTP into an urban biorefinery for converting wastes into various value-added chemicals and energy. </p><h3>Recent Findings</h3><p>Primary WWTP-based residuals produced are waste-activated sludge, biosolids, grit, and effluent. These components are becoming viable feedstocks for producing many potential products and can be recovered for commercial purposes as opposed to simple disposal. Example products include chemicals, energy, and transportable biofuels. An advantage to biorefinery operations composed of WWTPs is that they provide greener solutions while posing little to no threat to the environment. There has also been an increasing interest in co-feedstocks to WWTPs, such as municipal solids, food wastes, agriculture wastes, and lignocellulosic biomass, which can enhance product yields while providing sustainable management solutions to these additional waste streams.</p><h3>Summary</h3><p>Municipal wastewater influents generated within the USA have a chemical energy potential of 1.3 MJ/person/day which represents about 4% of the total daily electricity consumed globally. The cost of waste management is expected to rise by 5.5% by 2027 which can be significantly lowered by having WWTPs integrated into biorefineries. This review found that there is great potential for converting WWTPs into true biorefineries that can effectively produce numerous value-added chemicals. Often, minor process changes can be applied which will yield the envisoned products. This paper provides the framework towards both commercialization opportunities and needed research.</p></div>","PeriodicalId":528,"journal":{"name":"Current Pollution Reports","volume":"10 3","pages":"548 - 564"},"PeriodicalIF":6.4,"publicationDate":"2024-07-20","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141745156","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"环境科学与生态学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Cyanobacterial Blooms in Environmental Water: Causes and Solutions","authors":"Manogaran Lakshmikandan,&nbsp;Ming Li,&nbsp;Baozhu Pan","doi":"10.1007/s40726-024-00322-w","DOIUrl":"10.1007/s40726-024-00322-w","url":null,"abstract":"<div><h3>Purpose of Review</h3><p>The increasing frequency, magnitude, and duration of cyanobacterial blooms (CyBs) in coastal and inland waters globally are causing serious concern because of the infiltration of cyanotoxins into water reservoirs and their negative effects on aquatic ecosystems and human health. This worrying trend is further exacerbated by the elevated levels of nutrient release in aquatic ecosystems, rising atmospheric carbon dioxide (CO₂) concentrations, and increasing temperature associated with climate change, which have significantly exacerbated the issue of CyBs.</p><h3>Recent Findings</h3><p>Recent advancements in targeting key cyanobacterial traits have resulted in the development and implementation of next-generation physical methods that combine biological and chemical methodologies to effectively control CyBs. This comprehensive strategy successfully reduces the impact of secondary pollutants on aquatic ecosystems. Furthermore, by controlling nutrient concentrations and the composition of phytoplankton communities, this tailored approach provides an avenue for addressing CyBs’ negative impacts on water quality.</p><h3>Summary</h3><p>Extensive researches were conducted recently on cyanobacterial succession in eutrophic aquatic ecosystems to investigate the factors influencing bloom formation and to establish mitigation strategies for controlling and preventing CyBs in water bodies. Despite these advancements, there remain substantial challenges in comprehensively understanding the complex interplay between hydrological patterns, biological diversity, and chemical compositions within aquatic environments. To ensure the long-term sustainability of water resources, it is essential to implement a comprehensive management plan that addresses all aspects of CyB prevention. The review will assess recent advancements in strategies for preventing, controlling, and mitigating CyBs and evaluate their effectiveness and importance in the field, while also providing recommendations for future research in CyB control to further enhance our understanding and management of CyBs.</p></div>","PeriodicalId":528,"journal":{"name":"Current Pollution Reports","volume":"10 4","pages":"606 - 627"},"PeriodicalIF":6.4,"publicationDate":"2024-07-19","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141745159","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"环境科学与生态学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Measurements of the Optical Scattering Properties of Single Suspended Particles and Implications for Atmospheric Studies: A Review","authors":"Weijie Yao,&nbsp;Xiaole Pan,&nbsp;Yuting Zhang,&nbsp;Hang Liu,&nbsp;Jing Ye,&nbsp;Song Lü,&nbsp;Sinan Li,&nbsp;Yele Sun,&nbsp;Hang Su,&nbsp;Zifa Wang","doi":"10.1007/s40726-024-00323-9","DOIUrl":"10.1007/s40726-024-00323-9","url":null,"abstract":"<div><h3>Purpose of Review</h3><p>This review provides a comprehensive overview of the technological developments in polarized laser single particle measurement technology (PLSMT), as well as the results and findings obtained by PLSMT in field observations and laboratory studies. This overview of the measurement methods, theoretical simulations, and data mining emphasizes the importance of exploring future prospects for the application of PLSMT in atmospheric research.</p><h3>Recent Findings</h3><p>In recent years, the advancement of theoretical simulation methods and instrument measurement techniques has led to the application of PLSMT in the study of dust aerosols, anthropogenic pollution aerosols, atmospheric ice crystals, and bioaerosols. Moreover, researchers have achieved promising results in areas such as air quality modeling and forecasting, large-scale dust transport processes, cloud microphysical processes, and fine aerosol identification using observation data obtained from PLSMT. PLSMT enhances our understanding of the physical and chemical characteristics of atmospheric aerosols.</p><h3>Summary</h3><p>Atmospheric aerosols play a crucial role in various physical and chemical processes, and their properties are influenced by their morphology and chemical composition. The optical scattering method is a classical approach for determining the size of atmospheric aerosols, and the morphology of particulate matter can be determined based on the polarization distribution of backscattered light (90–180°). PLSMT, which was developed based on the optical scattering method, is an efficient in situ detection technique for determining the particle size and mixing state of aerosols.</p></div>","PeriodicalId":528,"journal":{"name":"Current Pollution Reports","volume":"10 4","pages":"648 - 661"},"PeriodicalIF":6.4,"publicationDate":"2024-07-18","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141745157","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"环境科学与生态学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"New Insights into Removing Antibiotic Resistance Genes: Environmental Factors, Technical Means, and Molecular Mechanisms","authors":"Li Pan,&nbsp;Ziye Yang,&nbsp;Liming Liu,&nbsp;Liqun Chen,&nbsp;Can Wang","doi":"10.1007/s40726-024-00320-y","DOIUrl":"10.1007/s40726-024-00320-y","url":null,"abstract":"<div><h3>Purpose of Review</h3><p>Antibiotic resistance has become a significant challenge around the world, and antibiotic resistance genes (ARGs) have also been recognized as emerging pollutants because of their wide distribution and adverse impacts on human health. Several approaches have been proposed to alleviate ARGs. However, limited knowledge exists on the summary of various strategies and their differences. To resolve these issues, we reviewed the elimination effects of ARGs in different ways and clarified the main molecular mechanisms.</p><h3>Recent Findings</h3><p>ARGs resistant to tetracyclines (<i>tet</i>) and sulfonamides (<i>sul</i>) have been found in many locations. In addition, various environmental factors, such as temperature, pH, and salinity may influence the removal of ARGs. Various traditional, emerging, and combined approaches have been used to eliminate ARGs, mainly associated with DNA damage, decrease in reactive oxygen species levels, and downregulated expression of ARGs-related function genes.</p><h3>Summary</h3><p>Collectively, this review systematically summarizes the environmental factors and strategies for ARGs removal. A comparison among these methods is made with a focus on performance and efficiency. Furthermore, we elucidate the main molecular mechanisms to eliminate ARGs. Ultimately, in terms of current studies, several advisable suggestions are proposed for further work.</p><h3>Graphical Abstract</h3>\u0000<div><figure><div><div><picture><source><img></source></picture></div></div></figure></div></div>","PeriodicalId":528,"journal":{"name":"Current Pollution Reports","volume":"10 4","pages":"722 - 743"},"PeriodicalIF":6.4,"publicationDate":"2024-07-18","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141745158","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"环境科学与生态学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Sustainable Organic Waste Management and Future Directions for Environmental Protection and Techno-Economic Perspectives","authors":"Pooja Sharma,&nbsp;Ambreen Bano,&nbsp;Surendra Pratap Singh,&nbsp;Sunita Varjani,&nbsp;Yen Wah Tong","doi":"10.1007/s40726-024-00317-7","DOIUrl":"10.1007/s40726-024-00317-7","url":null,"abstract":"<div><h3>Purpose of Review</h3><p>This review aims to critically assess contemporary challenges and prospective avenues in the sustainable handling and management of organic waste (OW), elucidating its environmental ramifications and exploring techno-economic perspectives. Reviewing current knowledge is synthesized to provide insights that will help develop innovative strategies and policies. These strategies and policies foster a holistic approach to mitigating the environmental impacts associated with OW while also addressing economic issues.</p><h3>Recent Findings</h3><p>The imperative of integrating advanced technologies and holistic environmental considerations into OW management is underscored by recent findings. Environmental footprints can be minimized through innovations such as decentralized processing systems. Further, understanding techno-economic dynamics reveals the potential for sustainable practices, indicating a shift towards circular economies. By integrating environmental and economic aspects of OW management, we can enhance waste management strategies.</p><h3>Summary</h3><p>The focus of this review is the significance of OW generation and management, including agricultural, municipal, and green sources, as well as microbial treatment platforms as a critical factor. The report discusses the benefits of anaerobic digestion and composting in OW treatment and the advantages of biotransformation in sustainable waste management through biofuel and biofertilizer (BioF) production. To maximize OW potential as a valuable resource for sustainable development, the review integrates environmental concerns with techno-economic perspectives. To unlock the full potential of OW as a valuable resource in sustainable development, this review addresses barriers. It advances future directions in OW handling and management by integrating environmental considerations with techno-economic perspectives.</p><h3>Graphical Abstract</h3>\u0000<div><figure><div><div><picture><source><img></source></picture></div></div></figure></div></div>","PeriodicalId":528,"journal":{"name":"Current Pollution Reports","volume":"10 3","pages":"459 - 477"},"PeriodicalIF":6.4,"publicationDate":"2024-07-05","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141551598","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"环境科学与生态学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"A Review of Atmospheric Microplastics: Sources, Characteristics, and Detection Method","authors":"Ning Zhang,&nbsp;Chongchong Zhang,&nbsp;Yiming Qin,&nbsp;Junfeng Wang,&nbsp;Xinlei Ge,&nbsp;Haiwei Li,&nbsp;Yuan Dai,&nbsp;Eleonora Aruffo","doi":"10.1007/s40726-024-00316-8","DOIUrl":"10.1007/s40726-024-00316-8","url":null,"abstract":"<div><p>Microplastics (MPs) are ubiquitous in the atmosphere, with an average lifetime of 1 week to several weeks. They originate from various sources, including direct emissions from industrial activities, fragmentation of larger plastic debris, and transport from terrestrial and aquatic environments. Atmospheric MPs (AMPs) have been reported to play vital impacts on human health, climate forcing, and air quality. It could absorb and release harmful chemicals, potentially affecting human health through ingestion or inhalation. Additionally, it could contribute to the absorption and scattering of solar radiation, potentially altering the Earth’s radiation balance. However, there is great uncertainty about their health and climate effects, mainly due to MPs undergoing complex physical, chemical, or biological aging in the atmosphere, which results in great changes in their chemical composition and morphonology. Therefore, the transformation mechanisms of AMPs are still poorly understood, hampering our ability to model responses to changes in AMPs.</p><p>This review summarizes the current knowledge on AMPs, focusing on their sources, characteristics, and detection methods. The variety of the detection techniques used to measure and characterize the AMPs present in literature makes it complex to compare the results. In addition, previous studies were mainly focused on fiber plastics in atmospheric deposition samples, whereas only few studies have been found in the literature about the identification of other types of plastics. We highlight the challenges associated with assessing the distribution, abundance, and composition of AMPs and discuss the need for standardized sampling and analytical protocols.</p></div>","PeriodicalId":528,"journal":{"name":"Current Pollution Reports","volume":"10 3","pages":"412 - 429"},"PeriodicalIF":6.4,"publicationDate":"2024-06-22","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141501523","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"环境科学与生态学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Acute and Chronic Health Impact of Fine Particulate Matter Constituents","authors":"Fuchao Wang,&nbsp;Cong Liu","doi":"10.1007/s40726-024-00315-9","DOIUrl":"10.1007/s40726-024-00315-9","url":null,"abstract":"<div><h3>Purpose of Review</h3><p>Ambient fine particulate matter (PM_2.5) is a complex mixture of various toxic constituents. Compared with abundance of studies on PM_2.5 total mass, limited evidence is available on the health effects of PM_2.5 constituents on human health outcomes. The purpose of this review is to summarize recent publications over five years on the short-term and long-term health effects of PM_2.5 constituents on human mortality, morbidity, and subclinical biomarkers.</p><h3>Recent Findings</h3><p>PM_2.5 constituents mainly include organic carbon (OC), black carbon (BC), sulfate (SO₄²⁻), nitrate (NO₃⁻), ammonia (NH₄⁺), and heavy metals, all of which were significantly associated with various mortality and morbidity. Exposure to BC, OC, NO₃⁻, SO₄²⁻, and NH₄⁺ mainly affected mortality and morbidity from cardiovascular diseases and respiratory diseases and might influence subclinical markers such as blood pressure and serum cytokines. NO₃⁻, OC, and BC were reported to be associated with increased risk of diabetes, cancer, and infant mortality.</p><h3>Summary</h3><p>This review systematically summarized the study evidence on the effects of the constituents of PM_2.5 on population health in recent years. BC, OC, soil dust, NO₃⁻, SO₄²⁻, and NH₄⁺ were significantly associated with multisystem health outcomes. We found that the majority of studies were investigating the short-term effects, and mainly focusing on mortality and morbidity endpoints, while there were relatively few literatures on subclinical indicators and other endpoints like adverse birth outcomes. Future studies should be supplemented in this area.</p></div>","PeriodicalId":528,"journal":{"name":"Current Pollution Reports","volume":"10 3","pages":"401 - 411"},"PeriodicalIF":6.4,"publicationDate":"2024-06-21","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141501531","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"环境科学与生态学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"A Review on Analytical Approaches for Ambient Ozone Open Data in Taiwan","authors":"Duy-Hieu Nguyen,&nbsp;Chih-Hsiang Liao,&nbsp;Xuan-Thanh Bui,&nbsp;Chung-Shin Yuan,&nbsp;Chitsan Lin","doi":"10.1007/s40726-024-00314-w","DOIUrl":"10.1007/s40726-024-00314-w","url":null,"abstract":"<div><h3>Purpose of Review</h3><p>The air quality in Taiwan is significantly impacted by ambient ozone (O₃) pollution, which poses a challenge in terms of control due to the involvement of precursors and influencing factors in its photochemical process. This review investigates the measures that have been implemented in Taiwan over the past two decades to address this issue and evaluate their effectiveness in reducing O₃ concentrations. Furthermore, it highlights relevant studies that have employed advanced methods to examine the O₃ problem.</p><h3>Recent Findings</h3><p>Comprehending the complex formation of O₃ and its driving factors is crucial in efficiently managing O₃ pollution. Nevertheless, accurately quantifying the impacts of these factors can be challenging due to their interconnections. To bridge this gap in knowledge, conducting a robust causality analysis becomes imperative to accurately quantify the causal influence of major factors. Furthermore, eliminating seasonal variations can improve the precision and accuracy of trend analyses concerning long-term changes in O₃ concentrations. Deep learning, in particular, holds significant advantages in predicting O₃ concentrations as it can capture non-linear and long-term memory characteristics effectively.</p><h3>Summary</h3><p>In summary, attaining acceptable O₃ levels in Taiwan is challenging due to its geographical location, which makes it susceptible to air pollution from both local sources as well as distant upwind areas. The utilization of advanced methods is essential for comprehensively studying the evolution of O₃ and formulating effective mitigation measures. While there is a necessity to develop new analytical methods, implementing existing robust methodologies can also provide valuable insights into the dynamics and impacts of O₃. By leveraging these approaches, we can enhance our comprehension of O₃ pollution in Taiwan and develop effective strategies to mitigate its harmful effects on air quality.</p></div>","PeriodicalId":528,"journal":{"name":"Current Pollution Reports","volume":"10 3","pages":"374 - 386"},"PeriodicalIF":6.4,"publicationDate":"2024-06-18","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141501525","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"环境科学与生态学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Wastewater-Based Surveillance of Mpox (Monkeypox): An Early Surveillance Tool for Detecting Hotspots","authors":"Md. Aminul Islam,&nbsp;Rakesh Kumar,&nbsp;Prabhakar Sharma,&nbsp;Shuxin Zhang,&nbsp;Prosun Bhattacharya,&nbsp;Ananda Tiwari","doi":"10.1007/s40726-024-00299-6","DOIUrl":"10.1007/s40726-024-00299-6","url":null,"abstract":"<div><h3>Purpose of Review</h3><p>This study aims to review recent literature reporting wastewater-based surveillance (WBS) of the monkeypox virus (MPXV) with a major focus on sample collection, processing, and public health safety issues.</p><h3>Recent Findings</h3><p>Various studies revealed the presence of MPXV genetic markers in sewage, wastewater treatment plants, and drainage systems of hospitals in multiple countries.</p><h3>Summary</h3><p>Mpox (formally monkeypox) has been identified in more than a hundred countries, confirming at least 93,937 cases from 06 May 2022 to 03 February 2024. The MPXV, the causative agent for mpox, is a zoonotic virus having genome DNA. Major symptoms of the disease are rash, fever, headache, and chills with lymph pain. It has about a 10% case fatality rate, without any approved vaccine, but researchers are investigating the development of therapeutic vaccines. The virus DNA signature has been long reported in urine, stool, saliva, semen, and spit samples of clinical patients, make feasible for tracking the virus in wastewater. Furthermore, recent studies have reported MPXV DNA from environmental samples. As MPXV is a zoonotic virus with possible multiple hosts (e.g., small mammals and rodents), their detection in environmental samples might indicate the possible circulation of the virus including non-human hosts. The persistence of the infective virus particles in the ambient environment has not been fully investigated. Also, their possible risks of transmission through the contaminated milieu are unknown. The WBS can be an effective tool for identifying their hotspots and trends in communities.</p><h3>Graphical Abstract</h3>\u0000<div><figure><div><div><picture><source><img></source></picture></div></div></figure></div></div>","PeriodicalId":528,"journal":{"name":"Current Pollution Reports","volume":"10 2","pages":"312 - 325"},"PeriodicalIF":6.4,"publicationDate":"2024-05-21","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://link.springer.com/content/pdf/10.1007/s40726-024-00299-6.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141115216","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"环境科学与生态学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Toxicity Research Progress of Nickel Oxide Nanoparticles Exposure in the Environment","authors":"Caixia Bai,&nbsp;Zhihao Zhang,&nbsp;Donggang Guo,&nbsp;Quanxi Zhang","doi":"10.1007/s40726-024-00306-w","DOIUrl":"10.1007/s40726-024-00306-w","url":null,"abstract":"<div><h3>Purpose of Review</h3><p>Nickel oxide nanoparticles (NiO NPs) have attracted considerable interest in multiple industries because of their distinct properties and wide range of potential applications. However, concerns regarding their potential adverse health effects have prompted extensive research efforts to understand their toxicity and develop appropriate safety guidelines.</p><h3>Recent Findings</h3><p>Recent studies have demonstrated that exposure to NiO NPs can induce harm in a variety of animal models, plants, ecological systems, and in vitro cell models. Research on the mechanism of signaling pathways implicated in respiratory system toxicity and hepatotoxicity has shown that NiO NPs can lead to organ damage by triggering downstream signaling through the nuclear factor kappa-B (NF-κB), mitogen-activated protein kinase (MAPK)/Smad, phosphoinositide 3-kinase (PI3K/AKT), and hedgehog signaling pathways. High-throughput RNA sequencing has been used in toxicity studies to detect important changes in the transcriptome at the mRNA and pathway levels. Additionally, NiO NPs have been found to cause NiO NPs induce neurotoxicity, genotoxicity, and ecotoxicity in plants and earthworms, potentially through mechanisms involving oxidative stress and inflammatory factors.</p><h3>Summary</h3><p>This review provides a comprehensive summary of current research progress on the health effects of NiO NPs, focusing on their application, routes of exposure, and potential toxicity mechanisms. The study also evaluates evidence on the impact of NiO NPs on organ systems, including the respiratory, liver, nervous, genotoxic, reproductive and developmental effects. Lastly, the review suggests further research directions to improve understanding of the toxic effects and mechanisms of NiO NPs for safer application.</p></div>","PeriodicalId":528,"journal":{"name":"Current Pollution Reports","volume":"10 3","pages":"498 - 512"},"PeriodicalIF":6.4,"publicationDate":"2024-05-18","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141062600","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"环境科学与生态学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}