Colloid and Polymer Science最新文献

{"title":"Natural surfactant extract from Juglans regia: extraction, evaluation of surface-activity and interfacial properties and preliminary characterization","authors":"Ambika Pradhan,&nbsp;Amitabha Bhattacharyya","doi":"10.1007/s00396-025-05396-6","DOIUrl":"10.1007/s00396-025-05396-6","url":null,"abstract":"<div><p>This study investigates extraction of natural surfactant, saponin from <i>Juglans regia</i> and evaluates its surface-activity and interfacial properties. The surfactant demonstrated effective surface activity, reducing surface tension to 44.95 mN/m, exhibited moderate foaming, emulsification and cleaning abilities. Foam stability indicated by an R5 value of 48.65% was moderate, and pH measurements revealed the extract as weakly acidic. Critical micelle concentration obtained from surface tension was consistent with values obtained from conductivity and dirt dispersion tests. The extracted surfactant was analysed using Thin-layer chromatography (TLC), Fourier-transform infrared spectroscopy (FTIR) and UV–visible spectroscopy (UV–Vis). TLC indicated the presence of various polar and non-polar compounds, while FTIR and UV–Vis confirmed the presence of saponin along with minor traces of flavonoids. Specifically, FTIR identified triterpenoid saponin in the extract. FTIR and UV–Vis analysis also indicated that <i>Juglans regia</i> extract could be used as a dye. The results indicated that natural surfactant extracted from <i>Juglans regia</i> possesses significant amphiphilic and surface-active properties. This identifies a new eco-friendly source of natural surfactant with potential applications in detergency, bioremediation, oil recovery and food and cosmetic industries.</p><h3>Graphical Abstract</h3>\u0000<div><figure><div><div><picture><source><img></source></picture></div></div></figure></div></div>","PeriodicalId":520,"journal":{"name":"Colloid and Polymer Science","volume":"303 6","pages":"1003 - 1014"},"PeriodicalIF":2.2,"publicationDate":"2025-03-04","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144100200","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"化学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Phase separation, binding nature, and physico-chemical variables of TX-100 + crystal violet mixture: effects of the electrolytes and hydrotropes","authors":"Howa Akter,&nbsp;Md. Rafikul Islam,&nbsp;Tajmul Hasan,&nbsp;Md. Zulhash Uddin,&nbsp;Javed Masood Khan,&nbsp;Priyankar Sen,&nbsp;Md. Anamul Hoque,&nbsp;Md Abdul Goni","doi":"10.1007/s00396-025-05394-8","DOIUrl":"10.1007/s00396-025-05394-8","url":null,"abstract":"<div><p>This study has explored the potential interactions between Triton X-100 (TX-100) and crystal violet dye (CV) in the presence of different electrolytes and hydrotrope (HDT) solutions by using cloud point (CP) measurement and UV–visible spectroscopic techniques. The studied electrolytes are sodium chloride (NaCl), sodium acetate (NaOAc), and sodium sulfate (Na₂SO₄), whereas the HDTs are sodium salicylate (NaSal), sodium benzoate (NaBenz), and 4-amino benzoic acid (4-ABA). There was a sharp increase in the CP values of the system studied in NaSal and NaBenz media due to “salting-in” effect, whereas the lowering in the magnitudes of CP was recorded in aqueous solutions of NaCl, NaOAc, Na₂SO₄, and 4-ABA as a result of “salting-out” effect. The extents of CP in the experimental system were varied with the enhancement of different electrolytes and HDTs concentration which followed the trend as <span>(normalsize {text{CP}}_{text{aq. NaSal}}&gt;{text{CP}}_{text{aq. NaBenz}}&gt;{text{CP}}_{text{aq. NaOAc}}&gt;{text{CP}}_{text{aq. NaCl}}&gt;{text{CP}}_{{text{aq. Na}}_{2}{text{SO}}_{4}}&gt;{text{CP}}_{aq.4-text{ABA}})</span>. The binding constant (<span>({K}_{b})</span>) for the complexation of CV and TX-100 was determined by using the Benesi–Hildebrand equation with the help of UV–Vis spectroscopic method. The degree of <span>({K}_{b})</span> was found to be dependent on the presence of salts and variation in temperatures. The recorded <span>({Delta G}_{c}^{0})</span> and <span>({Delta G}_{b}^{0})</span> values for the phase segregation and binding were found as positive and negative, respectively, in all experimental cases. The positive magnitudes of <span>({Delta G}_{c}^{0})</span> showed a decreasing trend by the boost of electrolytes and HDT concentrations. The appearances of <span>(-{Delta H}_{c}^{0})</span> and <span>({-Delta S}_{c}^{0})</span> values in the solutions of different electrolytes confirmed the H-bonding and dipole–dipole interactions being in function amid the surfactant/dye mixtures in the aqueous media, whereas <span>(+{Delta H}_{c}^{0})</span> and <span>(+{Delta S}_{c}^{0})</span> values found in aq. NaSal and aq. NaBenz media were indicative of hydrophobic interactions to be have occurred between TX-100 and CV dye species. Both <span>({Delta H}_{b}^{0})</span> and <span>({Delta S}_{b}^{0})</span> values of binding were found to be positive revealing the presence of ion–dipole and hydrophobic interactions which were responsible for the binding of the respective components within the experimental surfactant–dye system. These significant results will be of great resource of knowledge to the researchers in the respective fields as well as highly useful for the formulations of quality products in various textiles and pharmaceutical industries.</p><h3>Graphical Abstract</h3><div><figure><div><div><picture><source><img></source></picture></div></div></figure></div></div>","PeriodicalId":520,"journal":{"name":"Colloid and Polymer Science","volume":"303 6","pages":"1015 - 1030"},"PeriodicalIF":2.2,"publicationDate":"2025-03-04","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144100199","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"化学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Application of polydopamine and graphene oxide combination in poly (N-isopropylacrylamide)/poly (acrylamide-co-acrylic acid) bilayer hydrogels","authors":"Chengao Li,&nbsp;Sirui Chen,&nbsp;Xuanxuan Ding,&nbsp;Minying Wang,&nbsp;Fei Yu,&nbsp;Mingqing Yuan,&nbsp;Cuixia Lu,&nbsp;Hua Yang","doi":"10.1007/s00396-025-05389-5","DOIUrl":"10.1007/s00396-025-05389-5","url":null,"abstract":"<div><p>In recent years, polydopamine (PDA) and graphene oxide (GO) have garnered considerable attention as promising photothermal materials. However, research on the combined application of PDA and GO as photothermal agents, as well as their integration into poly(N-isopropylacrylamide) (PNIPAm) hydrogels, remains sparse. To address this knowledge gap, our study presents a novel, multifunctional bilayer hydrogel that exhibits simultaneous photoresponsiveness, thermoresponsiveness, and pH responsivity. By incorporating PDA@GO into a thermally and pH-sensitive poly(N-isopropylacrylamide)/poly(acrylamide-co-acrylic acid) bilayer hydrogel, the resultant hydrogel demonstrates enhanced performance in converting light energy to heat energy. Upon exposure to 808 nm laser irradiation, the thermal performance of PDA@GO with varying synthesis ratios was evaluated, revealing that a dopamine to graphene oxide synthesis ratio of 2:1 yields the most effective heat generation. The incorporation of PDA@GO significantly enhances the hydrogel's capacity to convert light energy into heat energy. The developed hydrogel exhibits excellent multiple responsiveness, indicating its potential for a wide range of applications. This research leverages the synergistic effects of PDA and GO in constructing hydrogels, thereby fostering advancements in the realm of multifunctional reactive materials.</p><h3>Graphical Abstract</h3>\u0000<div><figure><div><div><picture><source><img></source></picture></div></div></figure></div></div>","PeriodicalId":520,"journal":{"name":"Colloid and Polymer Science","volume":"303 5","pages":"971 - 983"},"PeriodicalIF":2.2,"publicationDate":"2025-03-03","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143883599","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"化学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Crystallization kinetics of poly(ε-caprolactone) and chlorinated polyethylene binary blends","authors":"Al Mamun","doi":"10.1007/s00396-025-05398-4","DOIUrl":"10.1007/s00396-025-05398-4","url":null,"abstract":"<div><p>The crystallization kinetics of poly(ε-caprolactone) (PCL) and chlorinated polyethylene (CPE) binary blends were investigated, focusing on the effects of varying CPE content and chlorine concentration. Differential scanning calorimetry (DSC) and polarized optical microscopy were used to study the non-isothermal and isothermal crystallization kinetics. The results show that addition of CPE significantly influenced the crystallization behavior of PCL, and the extent of this effect was strongly dependent on the chlorine content of the CPE. Blends with a higher chlorine content (48%) in CPE exhibited enhanced interactions and higher miscibility with PCL, whereas the lower chlorine content (25%) indicated the immiscible nature of the blends. The interaction energy density calculations supported the presence of stronger PCL-CPE interactions at higher chlorine concentrations. Owing to the higher miscibility, increasing the CPE content in the PCL/CPE blend decreased the relative crystallinity, lowered the melting peak, reduced the crystal growth rate, and slowed the overall crystallization process. These effects were more pronounced at higher chlorine levels, whereas lower chlorine levels were not significantly affected by the immiscible nature of the blend. The blend composition and crystallization temperature influenced the crystallization kinetics and melting behavior. Higher CPE concentrations resulted in less perfect and heterogeneous crystalline structures. These findings contribute to a better understanding of the crystallization kinetics of PCL/CPE blends and provide valuable insights for specific applications.</p><h3>Graphical abstract</h3><p>Crystallization kinetics of poly(ε-caprolactone) and chlorinated polyethylene binary blends</p>\u0000<div><figure><div><div><picture><source><img></source></picture></div></div></figure></div></div>","PeriodicalId":520,"journal":{"name":"Colloid and Polymer Science","volume":"303 5","pages":"959 - 970"},"PeriodicalIF":2.2,"publicationDate":"2025-03-03","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143883601","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"化学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Study of poly (butylene adipate-co-terephthalate)/beta-cyclodextrin/polyvinyl alcohol, doped Mg2+, coated recycled Fe3O4 particle carriers for enhancing immobilization penicillin G acylase performance","authors":"Monier Alhadi Abdelrahman Mohammed,&nbsp;Zhenbin Chen,&nbsp;Xueyan Du,&nbsp;Bin Li,&nbsp;Jinhan Zhang,&nbsp;Tai Kang","doi":"10.1007/s00396-025-05391-x","DOIUrl":"10.1007/s00396-025-05391-x","url":null,"abstract":"<div><p>In this study, Fe₃O₄ magnetic particles (MPs) were produced from nickel slag using molten oxidation and magnetic separation methods. After that, Fe₃O₄ MPs were coated with a blend of poly (butylene adipate-co-terephthalate)/beta-cyclodextrin/polyvinyl alcohol (PBAT/B-CD/PVA), and Mg²⁺ was doped during this process. Mg²⁺-Fe₃O₄@PBAT/B-CD/PVA MPs were then modified using γ-glycidoxypropyltrimethoxysilane (KH560) to produce Mg²⁺-Fe₃O₄@PBAT/B-CD/PVA-g-KH560 MPs. The immobilized PGA (Mg²⁺-Fe₃O₄@PBAT/B-CD/PVA-g-KH560-PGA MPs) was obtained through covalently bonding PGA under mild circumstances by a click reaction between the amino group of PGA and the epoxy group of KH560. Furthermore, a vibrating sample magnetometer (VSM), Fourier transform infrared spectroscopy (FTIR), X-ray diffraction (XRD), scanning electron microscopy-energy spectroscopy of dispersive x-rays (SEM–EDS), X-ray photoelectron spectrophotometry (XPS), and inductively coupled plasma mass spectrometry (ICP-MS) were used to characterize the magnetic composite structures. The results showed that the immobilized PGA had values of 31,574 U/g, 94.2%, and 113 mg/g for enzyme activity recovery (<i>EAR</i>), enzyme loading capacity (<i>ELC</i>), and enzyme activity (<i>EA</i>), respectively. Its enzyme activity was maintained at 74% after 12 cycles of usage. The Fe₃O₄@PBAT/B-CD/PVA MPs were prepared similarly to the preparation of Mg²⁺-Fe₃O₄@PBAT/b-CD/PVA MPs except that Mg²⁺ was not doped to it to adopt as control, and after 6 cycles of usage, the immobilized PGA (Fe₃O₄@PBAT/B-CD/PVA-g-KH560-PGA MPs) retained 50% of its original enzyme activity, with <i>EA</i>, <i>EAR</i>, and <i>ELC</i> values of 28,513 U/g, 85.2%, and 107 mg/g, respectively, which were lower than Mg²⁺-Fe₃O₄@PBAT/B-CD/PVA-g-KH560 MPs; this indicate that doped Mg²⁺ had positive impact on immobilized PGA.</p><h3>Graphical Abstract</h3><p>Preparation scheme of immobilized PGA (Mg⁺²-Fe₃O₄@PBAT/B-CD/PVA-g-KH560-PGA MPs)</p><div><figure><div><div><picture><source><img></source></picture></div></div></figure></div></div>","PeriodicalId":520,"journal":{"name":"Colloid and Polymer Science","volume":"303 5","pages":"937 - 957"},"PeriodicalIF":2.2,"publicationDate":"2025-02-25","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143883548","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"化学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Mechanical and temperature dependence of dielectric properties for Mg1−xCuxO/PMMA nanocomposites used in energy storage applications","authors":"Ayshah S. Alatawi,&nbsp;Dalia E. Abulyazied,&nbsp;Asma M. Alturki,&nbsp;H. M. Abomostafa","doi":"10.1007/s00396-025-05395-7","DOIUrl":"10.1007/s00396-025-05395-7","url":null,"abstract":"<div><p>This study presents an innovative approach to enhancing the mechanical and dielectric properties of poly(methyl methacrylate) (PMMA) films by embedding Mg₁₋ₓCuₓO nanoparticles with varying copper content (<i>x</i> = 0.05 to 0.2). The nanocomposite films, fabricated via a casting technique, exhibit a remarkable improvement in dielectric performance across a wide temperature range (30–180 °C) and frequency spectrum (0.1 Hz to 1 MHz). The incorporation of Mg₁₋ₓCuₓO nanoparticles significantly boosts the dielectric constant (<i>ε</i>′), with values increasing at elevated temperatures, indicating superior charge storage capability-critical for next-generation electronic applications. The electric odulus analysis reveals a temperature-dependent relaxation process, with interfacial polarization effects driving the observed peaks in dielectric loss (<i>ε</i>″) and imaginary modulus (<i>M</i>″). These peaks shift to higher frequencies with rising temperatures, highlighting enhanced charge carrier mobility. Furthermore, mechanical analysis demonstrates a substantial increase in longitudinal (<i>L</i>), shear (<i>G</i>), Young’s (<i>E</i>), and bulk (<i>B</i>) moduli with higher copper concentrations, offering superior mechanical strength alongside enhanced dielectric efficiency. This research paves the way for high-performance nanocomposite materials that meet the evolving demands of flexible electronics, capacitors, and sensors, offering a unique blend of mechanical robustness and dielectric excellence.</p><h3>Graphical abstract</h3>\u0000<div><figure><div><div><picture><source><img></source></picture></div></div></figure></div></div>","PeriodicalId":520,"journal":{"name":"Colloid and Polymer Science","volume":"303 5","pages":"923 - 936"},"PeriodicalIF":2.2,"publicationDate":"2025-02-25","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143883727","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"化学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Enhanced rheological performance of shear thickening fluids: effects of graphene oxide nanoplatelets and clay nanoparticles","authors":"Sajjad Astaraki,&nbsp;Hanieh Easavinejad,&nbsp;Hosein Hasannezhad,&nbsp;Seyed Reza Payami,&nbsp;Yaser Bagheri,&nbsp;Sayed Hassan Nourbakhsh,&nbsp;Ata Khabaz-Aghdam","doi":"10.1007/s00396-025-05392-w","DOIUrl":"10.1007/s00396-025-05392-w","url":null,"abstract":"<div><p>This study investigates the effects of graphene oxide nanoplatelets (GNPs) and bentonite clay nanoparticles on the rheological behavior of shear thickening fluids (STFs). STFs, which exhibit rapid viscosity increases under shear stress, were formulated using a base suspension of 35% silica nanoparticles in polyethylene glycol (PEG) and reinforced with either 2.5% or 5% GNPs or 2.5% clay. Rheological tests, including shear rate, frequency, and temperature sweeps, were conducted to analyze peak viscosity, critical viscosity, and the crossover points of storage modulus (G') and loss modulus (G''). Results reveal that GNPs significantly enhance the STF’s viscosity and shear sensitivity, with the 5% GNP-reinforced STF demonstrating the highest peak viscosity and lowest shear rates required for thickening, along with superior rigidity. Temperature-dependent testing highlights a marked decrease in viscosity with rising temperatures, attributable to increased molecular mobility. Frequency and strain-dependent analyses show that GNP-reinforced STFs offer greater structural integrity under dynamic loads, with the 5% GNP STF showing a quick transition to fluid-like behavior at higher moduli. This study underscores the value of GNPs, especially at higher concentrations, in tailoring STF properties for applications in impact resistance and adaptive damping.</p><h3>Graphical Abstract</h3><div><figure><div><div><picture><source><img></source></picture></div></div></figure></div></div>","PeriodicalId":520,"journal":{"name":"Colloid and Polymer Science","volume":"303 5","pages":"907 - 921"},"PeriodicalIF":2.2,"publicationDate":"2025-02-24","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143883726","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"化学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Kosmotropic salting-out validation using physicochemical and photophysical studies on Pluronic F98 micelles","authors":"Nitumani Tripathi,&nbsp;Sapana Sinha,&nbsp;Debabrata Seth,&nbsp;Ketan Kuperkar,&nbsp;Pratap Bahadur","doi":"10.1007/s00396-025-05393-9","DOIUrl":"10.1007/s00396-025-05393-9","url":null,"abstract":"&lt;div&gt;&lt;p&gt;Kosmotropic salts lower the cloud point (CP) in triblock copolymers (BCPs) and exhibit micellization at lower concentrations and temperatures. Our investigation utilizes various physiochemical techniques, including tensiometry, calorimetry, viscosity, spectroscopy, and scattering, to understand the self-assembly phenomenon. Furthermore, by employing photophysical methods, using Coumarin 151 (C-151) dye as a probe, the self-assembly mechanism in the highly hydrophilic F98 in water and NaCl solutions with temperature is reported. Adding NaCl decreases the CP of 10% w/v F98, inducing a significant influence on the micellization behavior. Such an effect is attributed to the dehydration of the PEO blocks of F98. The surface tension (γ) measurements provided an insight into the intermolecular hydrophobic interactions at the air–water interface, indicating the enhanced surface activity in the presence of NaCl as a function of temperature. As the temperature or NaCl concentration increases, the solution flow behavior in terms of relative viscosity &lt;span&gt;(left({eta }_{rel}right))&lt;/span&gt; notably rises due to the enhanced intermicellar interactions with the continued dehydration of the PEO shell of F98. The salting-out effect of the PEO and PPO blocks of F98 in the presence of NaCl was evaluated by observing changes in bond stretching through Fourier-transform infrared (FT-IR) spectroscopy. Two-dimensional nuclear Overhauser effect spectroscopy (2D-NOESY) revealed insights into the spatial arrangement and dynamic interactions of NaCl binding with the PEO corona (~ 3.0–4.0 ppm) of F98. This binding reduced hydration and significantly altered the micellar dynamics. Additionally, minor shifts observed in the PPO signals (~ 1.0–1.5 ppm) suggested indirect interactions, pointing to changes in the internal environment and segmental dynamics of the micellar core. The spectral behavior is further validated by evaluating optimum descriptors using computational simulations performed with the DFT/B3LYP method within the 3-21G basis set framework, utilizing the Gaussian 5.0.9 software. The absorption spectra under increased NaCl concentration and higher temperatures render the microenvironment around the probe C-151 more hydrophobic, suggesting the formation of H-type aggregation. Additionally, fluorescence excitation spectra indicated a blue shift with increasing NaCl concentration, further supporting H-type aggregation. Here, the average fluorescence lifetime remained constant at ~ 5.4 to ~ 5.7 ns, as observed from fluorescence emission decays. Such consistency in fluorescence lifetime, despite forming H-type and J-type aggregations, indicates that the structural changes around the probe do not significantly affect its excited-state dynamics. It has been observed that the addition of NaCl influences the spectral behavior of F98 due to the dehydration of thermosensitive regions as a function of temperature, likely due to the salting-out effect. Dynamic light s","PeriodicalId":520,"journal":{"name":"Colloid and Polymer Science","volume":"303 5","pages":"885 - 906"},"PeriodicalIF":2.2,"publicationDate":"2025-02-22","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143883722","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"化学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Synthesis and characterizations of amla-based novel hydrogel matrix for the targeted and controlled release of the anticancer 5-fluorouracil drug","authors":"Kibrya Farooq,&nbsp;Priyanka Mankotia,&nbsp;Kashma Sharma,&nbsp;Vishal Sharma,&nbsp;Vaneet Kumar,&nbsp;Vijay Kumar","doi":"10.1007/s00396-025-05388-6","DOIUrl":"10.1007/s00396-025-05388-6","url":null,"abstract":"<div><p>The primary objective of this study is to synthesize, optimize, and analyze a hydrogel derived from amla, designed for use as a pharmaceutical excipient to inhibit tumor cell growth. The hydrogel was characterized using FTIR, XRD, and TGA to confirm the formation of a crosslinked network. The physicochemical properties, including swelling capacity, water retention, porosity, density, gel fraction, in vitro degradation, pH of the aqueous extract, and drug activity, were comprehensively evaluated. The hydrogel achieved a maximum swelling capacity of 300%. The hydrogel demonstrated a porosity of 0.998 and a density of 2.5 g/cm³. Swelling percentages in various biological fluids were observed in the following order: 280% (urea) &gt; 245% (glucose) &gt; 205% (saline solution). The synthesized hydrogel exhibited a gel fraction of 83.5%. In vitro degradation studies revealed that the hydrogel degraded by 95.6% over 25 days, with an average daily degradation rate of 3.824%, making it suitable for long-term drug delivery applications. Drug release studies confirmed that the hydrogel is pH-responsive, with significantly higher swelling at pH 4 and maximum drug release observed at pH 4.5. Furthermore, the hydrogel exhibited prolonged drug release under acidic, basic, and neutral pH conditions for up to 70 h, with sustained release behavior across all pH environments. The optimal release rate was achieved under acidic or tumor-like pH conditions. Therefore, the hydrogel-based drug delivery system developed using amla as a novel matrix demonstrates promising potential for pharmaceutical applications, especially in tumor-targeted therapies.</p><h3>Graphical Abstract</h3>\u0000<div><figure><div><div><picture><source><img></source></picture></div></div></figure></div></div>","PeriodicalId":520,"journal":{"name":"Colloid and Polymer Science","volume":"303 5","pages":"867 - 883"},"PeriodicalIF":2.2,"publicationDate":"2025-02-20","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143883719","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"化学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Silver nanoparticles as antifungal agents in acrylic latexes: influence of initiator on nanoparticle encapsulation efficiency and leaching","authors":"Gabrielle Boivin,&nbsp;Jingjjing Wang,&nbsp;Mohammed Baalousha,&nbsp;Julien Gigault,&nbsp;Véronic Landry,&nbsp;Anna M. Ritcey","doi":"10.1007/s00396-025-05390-y","DOIUrl":"10.1007/s00396-025-05390-y","url":null,"abstract":"<div><p>Nanoparticles present undeniable benefits in the formulation of cosmetics, construction materials, and coatings due to their optical, mechanical, and antimicrobial properties. However, a major limitation of application of nanoparticles in composite materials is nanoparticle leaching, which could have potential negative impacts on ecosystems and living organisms. This study investigates the influence of using an organic vs. water-soluble initiators (azobisisobutyronitrile and potassium persulfate, respectively) on the encapsulation and subsequent leaching of silver nanoparticles (AgNPs) from acrylic latexes prepared by miniemulsion polymerization. For comparison purposes, a reference latex was also prepared by the simple post-addition of hydrophilic AgNPs. AgNP encapsulation efficiencies were determined from density gradient column separations and latex particle size analysis was performed by dynamic light scattering. The spatial distribution of AgNPs in dry films was determined by scanning electron microscopy coupled with energy-dispersive spectroscopy and by mapping Ag signal using laser ablation inductively coupled plasma-time of flight-mass spectrometry. AgNP leaching was determined by measuring the acrylic film silver content before and after exposure to conditions designed to simulate rainfall (water leaching). The encapsulation of AgNPs using miniemulsion polymerization decreases particle leaching with respect to films prepared from the post-addition technique. The use of the organic-soluble initiator results in a better encapsulation of AgNPs and better NP retention during water leaching. Therefore, nanoparticle encapsulation using miniemulsion polymerization and an organic-soluble initiator minimizes the release of AgNPs from dry films and thus could mitigate the negative environmental impact of AgNPs.</p><h3>Graphical Abstract</h3>\u0000<div><figure><div><div><picture><source><img></source></picture></div></div></figure></div></div>","PeriodicalId":520,"journal":{"name":"Colloid and Polymer Science","volume":"303 5","pages":"857 - 865"},"PeriodicalIF":2.2,"publicationDate":"2025-02-18","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143883690","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"化学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}